Details of the Drug

General Information of Drug (ID: DM2Y4FG)

Drug Name
PHA-793887
Synonyms Cyclin-dependent kinase inhibitor (cancer), Nerviano
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 361.5
Logarithm of the Partition Coefficient (xlogp) 1
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C19H31N5O2
IUPAC Name
N-[6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-methylbutanamide
Canonical SMILES
CC(C)CC(=O)NC1=NNC2=C1CN(C2(C)C)C(=O)C3CCN(CC3)C
InChI
InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)
InChIKey
HUXYBQXJVXOMKX-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
46191454
ChEBI ID
CHEBI:91371
CAS Number
718630-59-2
UNII
MKS45S912B
DrugBank ID
DB12686
TTD ID
D0P1CV
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cyclin-dependent kinase 1 (CDK1) TTH6V3D CDK1_HUMAN Inhibitor [1]
Cyclin-dependent kinase 2 (CDK2) TT7HF4W CDK2_HUMAN Inhibitor [1]
Cyclin-dependent kinase 4 (CDK4) TT0PG8F CDK4_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cyclin-dependent kinase 1 (CDK1) DTT CDK1 5.27E-108 1.97 3.12
Cyclin-dependent kinase 2 (CDK2) DTT CDK2 2.28E-06 0.12 0.19
Cyclin-dependent kinase 4 (CDK4) DTT CDK4 3.30E-72 0.65 2.39
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 2.1599 7.7713 0.0866 28.3217
ES8 GDSC1 -3.4736 6.8769 -5.286 63.8277
ES7 GDSC1 -2.209 5.1416 -3.284 60.3424
EW-1 GDSC1 -1.9711 3.6536 -2.5415 60.703
ES1 GDSC1 -1.6126 4.494 -2.4148 57.4206
MHH-ES-1 GDSC1; CTRP2 -0.5025 4.6247 -0.7689 44.1208
TC71 CTRP2 0.084 2.7804 0.0651 39.7672
U2OS GDSC1; CTRP2 0.1478 4.4342 -0.0334 39.7805
EW-18 GDSC1 0.2244 8.8355 -2.29 44.9131
SK-ES-1 GDSC1; CTRP2 0.3917 4.5177 0.2152 38.1756
TC-71 GDSC1 0.8982 6.3822 -0.4943 37.4109
EW-7 GDSC1 0.9824 4.4205 0.4132 33.0215
A-673 GDSC1; CTRP2 1.3426 3.3452 1.3322 31.3589
EW-13 GDSC1 1.4497 7.9825 -0.6894 35.0513
EW-11 GDSC1 1.5505 7.6695 -0.4429 33.6378
SK-N-MC CTRP2 1.6643 3.7451 1.6459 29.2422
SK-PN-DW GDSC1 1.9324 7.1833 0.1567 29.0625
NOS-1 [Human HNSCC] GDSC1 1.9449 11.0799 -1.7368 35.8962
SW1353 CTRP2 2.0104 5.2263 1.8353 27.4706
ES4 GDSC1 2.2107 14.4506 -3.1723 37.9445
EW-16 GDSC1 2.3003 8.0699 0.0703 27.7568
HuO9 GDSC1 2.3067 6.5475 0.8193 23.5132
ES5 GDSC1 2.4925 12.6418 -2.0247 34.5071
CHSA0108 GDSC1 2.5131 4.2635 2.0932 13.503
EW-3 GDSC1 3.3211 10.86 -0.4251 25.9331
CHSA0011 GDSC1 3.4418 5.1296 2.5397 6.1349
CADO-ES1 GDSC1 3.6606 6.3828 2.0885 8.9292
CAL-78 GDSC1; CTRP2 3.6808 5.5209 3.5867 16.0688
SJSA-1 GDSC1; CTRP2 3.923 9.5892 2.297 20.2737
H-EMC-SS GDSC1 3.9836 8.5046 1.2843 13.818
ES6 GDSC1 3.9937 5.7747 2.628 3.8021
HuO-3N1 GDSC1 4.1575 6.0182 2.619 3.4716
SaOS-2 GDSC1; CTRP2 4.4747 8.3069 3.4369 14.4162
EW-24 GDSC1 4.9961 6.3687 2.9009 0.546
NY GDSC1 5.0143 7.4875 2.4538 2.901
CHSA8926 GDSC1 5.3167 7.1252 2.7485 0.9089
CAL-72 GDSC1 5.4646 7.0356 2.842 0.4565
G-292 clone A141B1 GDSC1; CTRP2 5.9243 13.3059 2.3131 15.6528
HOS GDSC1; CTRP2 6.1458 8.1357 5.082 3.8539
Hs 822.T CTRP2 7.2723 8.5298 5.6152 0.4219
MG-63 GDSC1; CTRP2 7.5754 12.9531 3.7678 6.9683
Hs 888.T CTRP2 8.3598 13.7142 3.9245 5.2942
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 211 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.3516 4.2442 0.2146 38.3301
JK1 CTRP2 0.5335 5.247 0.2276 37.6002
JM1 GDSC1; CTRP2 -1.0044 6.3133 -1.7232 47.5393
BL-41 GDSC1 -5.7103 0.6756 -5.9564 82.4461
SU-DHL-16 GDSC1 -4.86 -0.5186 -4.9208 84.5777
WIL2 NS GDSC1 -4.6283 2.9006 -5.2374 74.1901
SIG-M5 GDSC1; CTRP2 -3.9924 -2.4497 -3.9924 66.8628
KMS-21-BM CTRP2 -3.969 0.4822 -3.9977 65.707
697 GDSC1; CTRP2 -3.9224 -1.1111 -3.9235 66.2399
NKM-1 GDSC1 -3.6587 1.0245 -3.8117 75.6434
MOLM-13 GDSC1; CTRP2 -3.5192 0.0203 -3.5277 63.3837
SUP-M2 GDSC1; CTRP2 -3.4815 1.7435 -3.5666 62.2444
NALM-6 GDSC1; CTRP2 -3.3275 0.5633 -3.3452 62.0174
MOLP-8 GDSC1; CTRP2 -3.3193 1.6662 -3.3914 61.4186
ST486 GDSC1; CTRP2 -3.1792 0.271 -3.188 61.2188
NU-DUL-1 GDSC1; CTRP2 -3.1594 0.3551 -3.1935 55.3283
Karpas-231 GDSC1 -3.1404 0.346 -3.1925 75.0363
EoL-1 GDSC1; CTRP2 -3.1023 1.1718 -3.1373 60.433
Pfeiffer CTRP2 -2.9226 4.5341 -3.3745 57.7736
JSC-1 GDSC1 -2.8811 15.8224 -8.6146 56.4174
NB4 GDSC1; CTRP2 -2.8225 0.2034 -2.8269 58.9816
SU-DHL-5 GDSC1 -2.7929 -0.6458 -2.7965 75.174
KMS-26 CTRP2 -2.7688 0.0506 -2.7714 58.6554
SU-DHL-6 GDSC1; CTRP2 -2.7067 0.8715 -2.7217 58.1211
SU-DHL-10 GDSC1; CTRP2 -2.6774 -0.4115 -2.6779 58.0922
MV4-11 GDSC1; CTRP2 -2.6749 0.3005 -2.6792 58.0174
P30/OHK GDSC1 -2.5939 2.5261 -2.9309 66.4494
GA-10 CTRP2 -2.5139 1.6871 -2.5569 56.732
KOPN-8 GDSC1 -2.4787 0.4108 -2.5094 70.2313
LC4-1 GDSC1 -2.1582 2.8919 -2.5418 63.0372
Sc-1 GDSC1 -2.1103 3.0294 -2.5236 62.5017
BC-1 GDSC1 -2.0656 1.2357 -2.1448 65.1684
SKM-1 CTRP2 -2.0345 0.6447 -2.0378 53.8062
SCC-3 GDSC1 -2.0172 0.783 -2.0543 65.4913
MLMA GDSC1 -2 4.6177 -2.8766 59.7406
MOLT-13 GDSC1; CTRP2 -1.9219 3.1721 -2.0666 52.8391
QIMR-WIL GDSC1 -1.9023 3.4946 -2.421 60.4444
SU-DHL-8 GDSC1; CTRP2 -1.8639 3.1241 -1.9992 52.4955
NCO2 CTRP2 -1.8423 3.0137 -1.9635 52.3766
NCI-H929 CTRP2 -1.8154 2.5838 -1.8929 52.2538
OCI-AML-3 GDSC1; CTRP2 -1.8088 1.4618 -1.824 52.2892
EB2 GDSC1 -1.737 5.6521 -2.9629 57.2413
ML-2 GDSC1 -1.7253 2.3741 -1.9554 60.5702
HC-1 GDSC1 -1.7164 2.7096 -2.0175 60.0687
Karpas-299 GDSC1; CTRP2 -1.7018 1.1041 -1.7077 51.5974
CESS GDSC1 -1.6406 2.3955 -1.8679 59.834
CML-T1 CTRP2 -1.634 1.9214 -1.6619 51.1325
ALL-PO GDSC1 -1.534 7.9006 -3.6592 54.8239
RPMI-8866 GDSC1 -1.5244 2.4885 -1.7608 58.73
JJN-3 GDSC1; CTRP2 -1.5024 3.1409 -1.618 50.2622
RPMI-8226 GDSC1; CTRP2 -1.4208 3.2974 -1.5496 49.7498
TUR GDSC1 -1.3973 1.6162 -1.4805 58.4094
DEL GDSC1; CTRP2 -1.3707 0.24 -1.3707 49.4004
KMS-34 CTRP2 -1.2534 3.526 -1.4002 48.7038
KHM-1B CTRP2 -1.242 3.854 -1.4343 48.6537
L-363 GDSC1; CTRP2 -1.2297 1.9778 -1.2496 48.4791
KMS-27 CTRP2 -1.2294 1.8814 -1.246 48.4747
VL51 GDSC1 -1.2061 8.685 -3.6629 52.9289
CA46 GDSC1; CTRP2 -1.1655 5.6364 -1.7164 48.3534
MOLT-16 GDSC1; CTRP2 -1.1343 1.8787 -1.1488 47.8438
RS4;11 GDSC1; CTRP2 -1.095 0.5726 -1.0951 47.5638
OCI-AML-5 GDSC1; CTRP2 -1.0946 2.3538 -1.1275 47.602
KMS-12-BM GDSC1; CTRP2 -1.0913 3.0878 -1.1786 47.6331
OCI-Ly3 CTRP2 -1.0623 5.082 -1.4713 47.6859
CTB-1 GDSC1 -1.029 3.3438 -1.4261 53.6715
PL-21 GDSC1 -1.015 2.766 -1.267 53.8076
GR-ST GDSC1 -0.9897 4.7496 -1.8288 52.7833
A3/Kawakami GDSC1; CTRP2 -0.9625 1.2781 -0.9646 46.6856
Karpas-422 GDSC1; CTRP2 -0.9558 5.3673 -1.4214 47.0998
Reh GDSC1; CTRP2 -0.9492 2.2117 -0.9713 46.6298
A4/Fukuda GDSC1; CTRP2 -0.9207 1.9895 -0.9344 46.4281
RPMI-8402 GDSC1; CTRP2 -0.9155 2.7077 -0.9632 46.4449
SU-DHL-1 GDSC1; CTRP2 -0.8961 2.0322 -0.9107 46.2665
Hs 611.T CTRP2 -0.8715 3.4518 -0.9852 46.2462
Kasumi-1 GDSC1; CTRP2 -0.8547 3.7003 -0.9983 46.1761
SR GDSC1; CTRP2 -0.8471 3.1728 -0.9298 46.0474
Farage GDSC1 -0.8445 2.0325 -0.9463 52.2812
SUP-T1 GDSC1; CTRP2 -0.8239 5.2835 -1.258 46.2959
NU-DHL-1 CTRP2 -0.8224 3.5041 -0.9393 45.9349
MHH-CALL-4 CTRP2 -0.813 3.4645 -0.9247 45.8668
Ramos.2G6.4C10 GDSC1 -0.8066 0.0071 -0.8066 52.0342
Loucy GDSC1 -0.7958 2.3199 -0.94 51.6856
KMS-11 GDSC1; CTRP2 -0.7925 6.098 -1.4316 46.2977
KE-97 CTRP2 -0.7717 3.3021 -0.8633 45.5707
OCI-Ly10 CTRP2 -0.7594 6.0853 -1.392 46.1033
CCRF-CEM GDSC1 -0.7288 2.7938 -0.9619 50.9001
HH [Human lymphoma] GDSC1 -0.7213 6.2007 -2.0983 50.5435
WSU-DLCL2 GDSC1; CTRP2 -0.7148 1.484 -0.7171 45.0366
CTV-1 GDSC1 -0.6503 4.6576 -1.4298 50.0544
MM1.S CTRP2 -0.6266 4.6623 -0.9105 44.9226
RPMI-6666 GDSC1; CTRP2 -0.6248 3.6471 -0.7468 44.6678
KE-37 GDSC1; CTRP2 -0.6191 2.5216 -0.6459 44.4554
U266B1 GDSC1; CTRP2 -0.6045 5.6645 -1.1116 45.0718
MN-60 GDSC1 -0.6023 11.6123 -4.4032 49.8208
OCI-Ly19 GDSC1; CTRP2 -0.5273 4.493 -0.7713 44.2416
BV-173 GDSC1; CTRP2 -0.518 2.7322 -0.5526 43.8028
DND-41 GDSC1; CTRP2 -0.4622 4.1466 -0.6428 43.7223
Namalwa GDSC1; CTRP2 -0.4621 4.6263 -0.7255 43.862
THP-1 GDSC1; CTRP2 -0.3933 3.8623 -0.528 43.192
ARH-77 GDSC1 -0.393 6.1946 -1.7506 48.1727
DoHH2 CTRP2 -0.3 5.77 -0.8065 43.2494
Ku812 GDSC1; CTRP2 -0.284 2.5407 -0.3025 42.2125
LP-1 GDSC1; CTRP2 -0.257 4.8963 -0.5565 42.6335
MOLM-16 CTRP2 -0.2553 3.5642 -0.3456 42.1974
SUP-HD1 GDSC1; CTRP2 -0.2431 3.2376 -0.3019 42.043
AMO1 GDSC1; CTRP2 -0.2325 3.5896 -0.3243 42.0515
M-07e CTRP2 -0.2117 4.8092 -0.4898 42.3068
DB GDSC1; CTRP2 -0.1945 5.0221 -0.5149 42.2794
P32/ISH GDSC1 -0.0578 3.0863 -0.2995 43.5372
MOTN-1 CTRP2 -0.0437 5.5849 -0.4801 41.5589
Daudi GDSC1; CTRP2 -0.0401 3.6648 -0.129 40.7795
RCH-ACV CTRP2 -0.0204 4.8959 -0.2998 41.0932
BC-3 GDSC1 -0.0066 2.9712 -0.2162 42.8501
Ri-1 CTRP2 0.0097 4.8246 -0.253 40.8645
KCL-22 GDSC1; CTRP2 0.0183 3.6466 -0.0654 40.3813
MOLT-3 CTRP2 0.0326 3.87 -0.0758 40.351
Ki-JK CTRP2 0.0447 2.9044 0.0191 40.048
EB1 CTRP2 0.0516 6.0676 -0.5021 41.1975
OCI-AML-2 GDSC1; CTRP2 0.0891 2.7497 0.0716 39.7289
MY-M12 GDSC1 0.0931 11.511 -3.6811 46.6248
KMS-20 CTRP2 0.1012 5.1667 -0.2247 40.4206
VAL GDSC1 0.1328 4.847 -0.6573 42.9333
SEM CTRP2 0.1349 3.7108 0.0509 39.6132
U-937 CTRP2 0.182 2.3933 0.1761 39.075
P12-Ichikawa GDSC1; CTRP2 0.1826 3.6725 0.1053 39.2795
Mono-Mac-1 CTRP2 0.2112 6.6109 -0.4848 40.5045
NOMO-1 GDSC1; CTRP2 0.369 3.8008 0.2886 38.055
PL21 CTRP2 0.3747 2.4452 0.3701 37.7876
PF-382 GDSC1; CTRP2 0.4224 4.4641 0.2569 37.9438
OPM-2 GDSC1; CTRP2 0.4482 5.0664 0.1736 38.0693
EM-2 GDSC1; CTRP2 0.5461 3.6496 0.4896 36.8093
Kasumi-2 CTRP2 0.6451 2.9427 0.6332 36.0102
Peer CTRP2 0.666 3.5531 0.6228 35.971
SU-DHL-4 GDSC1; CTRP2 0.6672 2.9952 0.6541 35.8667
H9 GDSC1 0.6725 11.1054 -2.9322 43.4873
MOLT-4 GDSC1 0.7029 5.1069 -0.1525 37.3963
MHH-PREB-1 GDSC1 0.7034 3.3593 0.4603 34.5752
Hs 445 GDSC1 0.7177 7.3214 -1.1007 40.2059
EJM GDSC1; CTRP2 0.7512 6.181 0.2299 36.7721
BE-13 GDSC1 0.7605 3.7838 0.3961 34.5378
KMS-28BM CTRP2 0.8536 5.9713 0.3993 35.9415
MOLP-2 CTRP2 0.8619 4.0241 0.7854 34.7746
ALL-SIL GDSC1; CTRP2 0.9197 3.7975 0.8683 34.3097
HuT 78 CTRP2 0.9234 4.514 0.7869 34.5557
JURL-MK1 GDSC1; CTRP2 0.9734 4.6882 0.8128 34.3001
HL-60 GDSC1; CTRP2 0.9919 4.3504 0.8837 34.0119
F-36P CTRP2 0.9984 5.9319 0.5679 34.9438
KMS-18 CTRP2 1.0002 5.8119 0.6012 34.8416
Raji GDSC1; CTRP2 1.0202 3.8954 0.9651 33.6529
BL-70 CTRP2 1.0512 4.2283 0.9624 33.5564
Karpas-45 GDSC1 1.132 4.7394 0.4488 31.9132
KYO-1 CTRP2 1.1431 4.9874 0.9426 33.304
L-540 GDSC1; CTRP2 1.1574 4.2168 1.0766 32.8245
KMOE-2 GDSC1 1.1765 5.4345 0.2066 32.8851
SUP-B15 GDSC1; CTRP2 1.1771 4.1298 1.1071 32.6578
RL GDSC1; CTRP2 1.196 6.9889 0.4681 34.5239
Jurkat CTRP2 1.2073 4.447 1.1004 32.5781
EHEB CTRP2 1.3046 6.3963 0.7715 33.2721
P31/FUJ GDSC1; CTRP2 1.4352 4.2632 1.3655 30.9397
JVM-3 GDSC1; CTRP2 1.5202 4.4851 1.4289 30.4465
HT GDSC1; CTRP2 1.5698 3.3061 1.5643 29.8287
Mono-Mac-6 GDSC1; CTRP2 1.5863 14.5518 -2.3227 38.7601
Jiyoye GDSC1 1.6017 5.0682 0.8043 27.1645
ATN-1 GDSC1 1.6028 5.3007 0.7042 27.7659
KM-H2 GDSC1; CTRP2 1.6474 5.2023 1.4468 29.9671
U-698-M GDSC1 1.6576 4.3896 1.145 24.6664
L-1236 GDSC1 1.6979 4.2483 1.2435 23.7829
SUP-T11 CTRP2 1.7092 5.5677 1.4344 29.8058
JeKo-1 CTRP2 1.7418 3.7015 1.7276 28.7121
KY821 GDSC1 1.7625 7.2229 -0.0253 30.7886
AML-193 CTRP2 1.7737 4.035 1.7418 28.5589
JVM-2 GDSC1; CTRP2 1.8499 5.8672 1.514 29.0817
HPB-ALL CTRP2 1.9988 3.9366 1.981 27.0121
MOLM-6 CTRP2 2.0307 5.6385 1.7679 27.6365
Granta-519 GDSC1; CTRP2 2.048 7.4623 1.2275 29.3973
DG-75 GDSC1 2.118 7.647 0.1081 28.4118
LAMA-84 GDSC1; CTRP2 2.2772 6.7353 1.7256 27.0065
BALL-1 GDSC1 2.2937 6.8537 0.6587 24.5611
GDM-1 GDSC1; CTRP2 2.373 6.3229 1.9583 25.8981
TALL-1 [Human adult T-ALL] CTRP2 2.5173 10.2021 0.6012 29.8863
HD-MY-Z CTRP2 2.5434 6.612 2.0548 25.034
HEL GDSC1; CTRP2 2.5897 6.9617 1.989 25.1274
HDLM-2 GDSC1; CTRP2 2.6747 4.3359 2.6574 22.5073
KO52 CTRP2 2.7141 3.1396 2.7141 22.1867
TF-1 CTRP2 2.8227 4.7714 2.777 21.6177
Mino CTRP2 2.8722 4.6561 2.8402 21.2412
Ci-1 CTRP2 2.8902 4.9627 2.8258 21.2318
K-562 GDSC1; CTRP2 2.9226 6.4587 2.516 22.2311
MEG-01 GDSC1 2.9353 8.7997 0.2761 23.9645
HAL-01 GDSC1 2.9942 5.5455 1.9469 12.4778
MHH-CALL-3 CTRP2 3.0122 9.9785 1.2045 26.592
RC-K8 GDSC1 3.5755 4.7325 2.8411 3.3332
HEL 92.1.7 CTRP2 3.6066 7.7571 2.7785 19.283
WSU-NHL GDSC1 3.6361 9.4623 0.5331 19.8423
L-428 GDSC1; CTRP2 3.6588 6.5541 3.2858 17.2227
SET-2 CTRP2 3.8077 7.896 2.9319 18.146
YT GDSC1 3.819 11.3804 -0.2771 23.4922
CMK CTRP2 4.0357 8.2964 2.9956 17.2902
KG-1 GDSC1 4.211 9.8521 0.7902 16.3404
ROS-50 GDSC1 4.3384 8.682 1.4608 11.4827
OCI-M1 GDSC1; CTRP2 4.3467 9.8416 2.5954 18.0642
TK [Human B-cell lymphoma] GDSC1 4.7063 10.8385 0.6718 15.5511
ME1 GDSC1 4.7724 6.2821 2.8375 1.0291
P3HR-1 CTRP2 5.2058 13.6279 1.533 20.0208
ME1 CTRP2 5.562 6.872 5.1823 4.6764
SK-MM-2 GDSC1; CTRP2 6.4117 14.5118 2.1127 15.4547
MC116 GDSC1; CTRP2 7.4881 8.7066 5.6399 0.2638
KMM-1 CTRP2 7.8663 11.5487 4.6216 3.2438
Karpas-620 GDSC1; CTRP2 7.9324 9.2905 5.6016 0.1897
REC-1 CTRP2 8.669 10.3171 5.5132 0.1488
Toledo CTRP2 9.1716 19.2724 1.8202 11.9634
⏷ Show the Full List of 211 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 0.5048 2.8289 0.4936 36.9419
TE15 CTRP2 3.1411 6.3863 2.7764 20.6289
KYSE-270 GDSC1 0.9042 2.2482 0.8824 30.7862
KYSE-140 GDSC1; CTRP2 1.8564 6.8559 1.2291 30.0044
KYSE-180 GDSC1; CTRP2 1.9214 4.7312 1.8234 27.799
TE-11 GDSC1; CTRP2 2.4231 3.8172 2.4189 24.1395
TE-15 GDSC1 2.4521 10.1997 -0.8454 31.0329
TE-4 GDSC1; CTRP2 2.6149 5.3911 2.4577 23.3869
OE21 GDSC1; CTRP2 2.6507 5.2166 2.5295 23.0231
TE-6 GDSC1; CTRP2 2.6591 4.7753 2.6034 22.7416
TE-9 GDSC1; CTRP2 2.7189 4.1903 2.7096 22.1858
TE-5 GDSC1; CTRP2 2.7823 7.5905 1.9686 24.6256
TE-10 GDSC1; CTRP2 3.1214 7.4908 2.369 22.1853
T.T GDSC1 3.1949 4.3987 2.695 5.8291
TE-14 CTRP2 3.2415 7.1864 2.6122 20.9392
KYSE-70 GDSC1; CTRP2 3.2978 6.7522 2.8277 19.9764
KYSE-510 GDSC1; CTRP2 3.4465 5.1502 3.394 17.4853
EC-GI-10 GDSC1; CTRP2 3.815 5.6349 3.7097 15.2146
COLO 680N GDSC1; CTRP2 3.8718 7.7756 3.0492 17.5202
KYSE-410 GDSC1; CTRP2 4.1967 10.3299 2.218 19.8794
KYSE-450 GDSC1; CTRP2 4.2317 7.2817 3.6306 14.2931
KYSE-520 GDSC1; CTRP2 4.2723 7.106 3.7441 13.7438
KYSE-150 GDSC1; CTRP2 5.0318 10.7283 2.813 15.5943
TE-1 GDSC1; CTRP2 5.2743 8.525 4.1156 9.7267
OE33 GDSC1; CTRP2 5.515 10.2728 3.4742 11.8526
TE-8 GDSC1 5.6777 8.1573 2.504 1.6953
OE19 GDSC1; CTRP2 6.508 8.9283 4.9682 3.7038
KYSE-30 CTRP2 6.6954 13.2029 2.9922 11.5275
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.4847 6.974 2.9514 18.9738
MZ-PC-1 GDSC1 -1.5009 6.8381 -3.1793 55.1581
Panc 08.13 GDSC1; CTRP2 0.4135 4.6349 0.2187 38.0824
HuP-T4 GDSC1; CTRP2 0.5092 5.6096 0.1166 37.9805
BxPC-3 GDSC1; CTRP2 1.5128 5.0174 1.3368 30.7777
QGP-1 GDSC1; CTRP2 1.6241 9.2966 0.0624 34.1327
L3.3 CTRP2 1.6885 3.5511 1.6786 29.0525
Panc 03.27 GDSC1; CTRP2 1.9778 5.7448 1.6844 28.092
SU.86.86 GDSC1; CTRP2 2.0476 6.0714 1.6751 27.9013
HPAC GDSC1; CTRP2 2.187 6.4507 1.7171 27.3171
KP-4 GDSC1; CTRP2 2.2619 6.576 1.76 26.935
DAN-G GDSC1; CTRP2 2.7491 3.57 2.749 21.9542
KP-3 GDSC1; CTRP2 2.7957 8.3906 1.666 25.6538
PSN1 GDSC1; CTRP2 3.0517 8.902 1.7184 24.736
Panc 10.05 GDSC1; CTRP2 3.2727 10.3337 1.3058 25.5351
PANC-1 CTRP2 3.5014 7.2622 2.8623 19.2604
SNU-213 CTRP2 3.5353 5.284 3.47 16.9377
HuP-T3 GDSC1; CTRP2 3.6664 7.6305 2.8929 18.6824
PK-59 CTRP2 3.77 8.6571 2.5646 19.6566
YAPC GDSC1; CTRP2 3.7934 7.6194 3.0313 17.8029
MIA PaCa-2 GDSC1; CTRP2 3.8244 6.5826 3.4559 16.1068
Hs 766T GDSC1; CTRP2 3.9061 7.7147 3.1105 17.1906
KP-2 GDSC1; CTRP2 4.0605 9.0228 2.6946 18.3975
CFPAC-1 GDSC1; CTRP2 4.2075 8.2838 3.1766 16.1326
Panc 05.04 CTRP2 4.3902 10.2885 2.4243 18.6191
PaTu 8988t GDSC1; CTRP2 4.4616 11.0678 2.1166 19.6134
Capan-1 GDSC1; CTRP2 4.5979 9.7444 2.8842 16.3195
Panc 04.03 GDSC1; CTRP2 4.9563 7.1498 4.4429 9.1766
SW1990 GDSC1; CTRP2 4.9585 9.8344 3.1827 14.2751
TCC-Pan2 CTRP2 4.9737 9.7003 3.2622 14.9345
HPAF-II GDSC1; CTRP2 4.9749 10.2285 3.0056 14.9524
Capan-2 GDSC1; CTRP2 4.9797 10.1791 3.0342 14.8263
PL4 GDSC1 5.0919 8.9831 1.8241 6.9633
PaTu 8902 GDSC1; CTRP2 5.2468 11.2066 2.7718 15.2812
PaTu 8988s CTRP2 5.8144 12.2099 2.7679 14.1022
Panc 02.03 GDSC1; CTRP2 5.8572 10.4527 3.6824 10.2841
AsPC-1 GDSC1; CTRP2 6.172 10.8656 3.7392 9.4341
PK-45H CTRP2 6.3688 10.1897 4.2355 6.9984
SUIT-2 GDSC1; CTRP2 6.7669 10.0914 4.5869 4.8644
SNU-410 CTRP2 7.286 12.52 3.774 7.3801
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 0.7872 7.4108 -0.1168 37.4852
RPMI-7951 GDSC1; CTRP2 0.8632 5.2909 0.5765 35.4049
MZ-MEL-2 GDSC1 0.9349 8.7639 -1.5592 40.0764
G-361 GDSC1; CTRP2 0.951 4.7175 0.7837 34.4689
Hs 852.T CTRP2 1.1922 6.4231 0.641 34.0472
Hs 944.T CTRP2 1.2472 5.6656 0.9074 33.0561
Hs 936.T CTRP2 1.4552 5.738 1.1163 31.6898
Mel Ho GDSC1; CTRP2 1.7305 4.8044 1.6079 29.1524
COLO 679 GDSC1 1.7392 8.8807 -0.8472 34.1763
WM35 GDSC1 1.8427 9.3214 -0.9657 34.0942
Mel JuSo GDSC1; CTRP2 1.9012 6.4444 1.4075 29.2735
WM793 GDSC1; CTRP2 1.9137 6.329 1.4556 29.0727
WM115 GDSC1; CTRP2 2.3015 5.8857 2.0019 25.9684
Hs 294T CTRP2 2.3247 4.6666 2.2615 24.9946
A-375 GDSC1; CTRP2 2.5162 4.324 2.4939 23.5804
WM88 CTRP2 2.6032 6.0042 2.2998 23.9798
MDA-MB-435S CTRP2 2.6618 6.1702 2.3178 23.7355
LOX-IMVI GDSC1; CTRP2 2.6977 7.1614 2.0359 24.6358
CJM [Human melanoma] CTRP2 2.7029 3.1244 2.7029 22.2617
HMCB CTRP2 2.8218 4.191 2.8148 21.493
WM266-4 CTRP2 2.8736 5.8626 2.632 21.9633
WM1799 CTRP2 2.9267 5.8139 2.7021 21.5497
SK-MEL-2 GDSC1; CTRP2 3.1497 6.6842 2.6901 20.9191
A-388 GDSC1 3.1744 4.4856 2.6336 6.3926
CHL-1 GDSC1 3.3172 12.9859 -1.4913 30.0276
COLO 829 GDSC1; CTRP2 3.4067 7.8798 2.5178 20.8232
WM1552C GDSC1 3.4117 7.1313 1.5147 14.1422
IGR-1 GDSC1; CTRP2 3.432 7.2035 2.8102 19.6535
IST-MEL1 GDSC1 3.5039 4.9177 2.6948 4.7043
HT-144 GDSC1; CTRP2 3.5707 5.0105 3.5413 16.5794
DJM-1 GDSC1 3.6153 4.9472 2.7649 3.8043
A2058 GDSC1; CTRP2 3.6218 4.924 3.6022 16.2056
SK-MEL-5 GDSC1; CTRP2 3.6586 6.0719 3.4331 16.6841
IGR-37 GDSC1; CTRP2 3.7626 4.5167 3.7617 15.2047
451Lu GDSC1 3.7919 5.7133 2.518 5.1884
A101D GDSC1; CTRP2 3.8612 4.5376 3.8606 14.5468
RVH-421 GDSC1; CTRP2 3.8902 4.7812 3.8862 14.365
SK-MEL-30 GDSC1; CTRP2 3.8942 7.4105 3.2223 16.7929
COLO 800 GDSC1; CTRP2 3.8951 7.8762 3.0314 17.5257
UACC-62 GDSC1; CTRP2 3.9519 5.2165 3.9223 14.0406
G-mel GDSC1 3.9929 8.6867 1.2012 14.3601
CP66-MEL GDSC1 4.1062 5.7844 2.6956 3.0372
LB373-MEL-D GDSC1 4.2308 6.4287 2.4733 4.3575
HMV-II GDSC1 4.5316 10.7571 0.5837 16.5966
K029AX CTRP2 4.5549 8.4182 3.4663 14.0967
SH-4 GDSC1 4.6612 6.7906 2.5659 2.8001
MeWo GDSC1; CTRP2 4.667 6.2831 4.4698 9.877
COLO 741 CTRP2 4.6886 19.6845 -1.9361 30.489
SK-MEL-3 GDSC1; CTRP2 4.7658 9.8013 3.017 15.3906
SK-MEL-31 CTRP2 4.835 11.8125 2.0994 18.8016
IPC-298 GDSC1; CTRP2 4.8724 10.4228 2.8154 15.9478
Hs 839.T CTRP2 4.9202 7.1117 4.4219 9.3545
WM983B CTRP2 4.9832 8.3047 3.9421 11.1227
LB2518-MEL GDSC1 5.0142 6.4173 2.8901 0.5739
SK-MEL-1 GDSC1; CTRP2 5.0931 7.3283 4.5036 8.582
COLO 783 GDSC1 5.153 6.2953 2.9876 0.2019
Hs 938.T GDSC1 5.195 6.8617 2.7975 0.8045
IGR-39 CTRP2 5.2346 8.372 4.152 9.6684
CP50-MEL-B GDSC1 5.236 7.0012 2.7615 0.9236
UACC-257 GDSC1; CTRP2 5.2382 12.0978 2.3221 17.0565
VMRC-MELG GDSC1 5.3236 6.7085 2.9055 0.3399
Hs 940.T GDSC1; CTRP2 5.3341 11.5481 2.6802 15.4547
SK-MEL-28 GDSC1; CTRP2 5.3555 7.8857 4.5013 7.9507
A-431 GDSC1 5.3754 15.7925 -1.27 23.0309
GAK GDSC1 5.4566 6.7233 2.9491 0.1861
M14 GDSC1 5.4609 6.9142 2.8841 0.3362
MMAc-SF GDSC1 5.5606 7.1356 2.8429 0.4044
MZ-MEL-7 GDSC1 5.7414 7.4815 2.788 0.4754
Hs 895.T CTRP2 5.9756 8.8212 4.5982 6.2129
COLO 792 GDSC1; CTRP2 6.2337 8.0247 5.2072 3.1702
WM278 GDSC1 6.307 7.8565 2.862 0.1332
SK-MEL-24 GDSC1; CTRP2 6.5859 8.5948 5.1874 2.6816
WT2-iPS GDSC1; CTRP2 6.6951 9.3763 4.8847 3.7531
Hs 934.T CTRP2 7.1304 11.7912 4.0181 6.6288
Hs 688(A).T CTRP2 12.292 28.6544 -0.5742 15.0424
EquiPSC Line K2 GDSC1 4.8127 9.0516 1.6117 9.1121
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 -2.3224 5.7755 -3.6366 60.2522
OACM5.1 C GDSC1 0.8694 7.9229 -1.2276 39.6685
KYSE-220 GDSC1 2.2367 11.5663 -1.7155 34.6658
KYAE-1 GDSC1 2.8169 7.1069 1.0144 19.9904
KYSE-50 GDSC1 2.8252 11.4091 -1.1209 30.5483
OACP4 C GDSC1 2.8347 3.838 2.6092 8.0996
FLO-1 GDSC1 2.9321 5.4236 1.9508 12.7032
ESO-51 GDSC1 2.9739 7.2558 1.0793 18.9072
SK-GT-4 GDSC1 3.6107 8.1118 1.187 15.7561
TE-12 GDSC1 4.5629 11.2899 0.3446 17.8761
HCE-4 GDSC1 5.9028 7.7014 2.7707 0.446
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 2.4256 12.1024 -0.3532 32.6721
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -0.6003 13.6237 -4.0981 47.0085
SJNB-7 GDSC1 0.0639 9.2517 -2.6423 46.0719
IMR-5 GDSC1 0.371 4.6106 -0.3134 40.2395
GI-ME-N GDSC1 0.6769 5.78 -0.4593 38.654
KP-N-YS GDSC1 0.7562 5.6935 -0.3401 37.7467
CHP-134 GDSC1 1.0461 6.5336 -0.4123 36.2574
KP-N-SI9s CTRP2 1.2534 5.7579 0.8912 33.0852
Kelly GDSC1; CTRP2 1.4538 4.6352 1.337 30.9728
NB1 GDSC1; CTRP2 1.4717 3.82 1.4425 30.5615
SJNB-17 GDSC1 1.5876 6.9534 -0.0675 31.8802
MHH-NB-11 GDSC1; CTRP2 1.9018 5.4848 1.663 28.4093
CHP-126 GDSC1; CTRP2 1.9521 6.0615 1.5736 28.5518
SK-N-MC-IXC GDSC1 2.6033 4.0899 2.2615 11.8137
SK-N-AS GDSC1; CTRP2 3.1387 8.1662 2.1187 23.0546
SK-N-BE(2) CTRP2 3.1734 10.7305 1.0242 26.7244
NH-6 CTRP2 3.2659 10.0964 1.4074 25.2125
NB69 GDSC1 3.3302 5.32 2.3525 8.0077
SJNB-14 GDSC1 3.6347 4.9806 2.7628 3.7622
SJNB-13 GDSC1 3.6503 8.3223 1.1138 16.1155
SK-N-DZ GDSC1; CTRP2 3.6954 6.3295 3.3977 16.7021
CHP-212 GDSC1; CTRP2 3.7512 7.982 2.8368 18.6644
TGW GDSC1 3.8249 6.4189 2.1957 7.5769
SK-N-BE(2)-M17 GDSC1 3.8998 7.0942 1.9186 9.4635
GOTO GDSC1 4.0066 11.9266 -0.3998 23.4357
SJNB-12 GDSC1 4.0812 6.4275 2.3746 5.4718
SJNB-6 GDSC1 4.1094 10.4001 0.4405 18.7634
NB(TU)1 GDSC1 4.3124 6.6515 2.4209 4.5433
SJNB-5 GDSC1 4.3329 7.7841 1.8939 8.374
SiMa GDSC1 4.4142 7.6589 2.0099 7.3018
SK-N-FI GDSC1; CTRP2 4.4495 7.5504 3.7462 13.2562
SJNB-10 GDSC1 4.5043 8.6502 1.5942 10.0632
LA-N-6 GDSC1 4.9011 7.1007 2.5606 2.4227
NH-12 GDSC1 5.1475 7.2508 2.6216 1.7127
SK-N-SH GDSC1; CTRP2 5.4846 8.2891 4.4271 7.9615
KP-N-YN GDSC1; CTRP2 6.944 11.3981 4.0753 6.6887
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 -0.1849 6.1998 -0.7969 42.7256
SNU-1079 CTRP2 1.7095 5.3077 1.4925 29.6104
HuCC-T1 GDSC1; CTRP2 2.3649 7.6157 1.512 27.468
HuH-28 CTRP2 3.521 6.2616 3.2282 17.8432
SNU-869 CTRP2 4.3675 10.3591 2.3686 18.8879
SNU-1196 CTRP2 4.6385 8.5817 3.4737 13.8593
SNU-308 CTRP2 5.515 7.2439 4.9616 5.6881
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC70 GDSC1 -1.5107 0.5208 -1.5203 60.5121
HCC1806 GDSC1; CTRP2 -0.3546 2.5781 -0.3765 42.6904
DU4475 GDSC1; CTRP2 -0.0063 6.0827 -0.5694 41.5671
HCC1599 GDSC1 0.0047 3.6264 -0.3786 43.2349
HCC1187 GDSC1 0.0502 2.8728 -0.1322 42.0941
HMC-1-8 CTRP2 0.208 2.8061 0.1911 38.9361
MDA-MB-468 GDSC1; CTRP2 0.2182 3.5059 0.1585 38.9943
OCUB-M GDSC1 0.7196 3.2747 0.5007 34.2455
CAL-51 GDSC1; CTRP2 0.8502 4.4577 0.717 35.0294
HCC2157 GDSC1 1.0307 10.998 -2.5415 41.4069
HCC1954 GDSC1; CTRP2 1.3277 5.404 1.0566 32.3115
SK-BR-3 CTRP2 1.7773 4.4669 1.7046 28.6724
HCC2218 GDSC1; CTRP2 1.9353 9.6148 0.2552 32.6312
AU565 GDSC1; CTRP2 2.172 4.4038 2.1281 25.946
Hs 578T GDSC1; CTRP2 2.1728 3.5333 2.1704 25.8013
HCC1143 CTRP2 2.2508 4.1758 2.2281 25.3496
CAL-85-1 GDSC1; CTRP2 2.789 7.5772 1.9807 24.563
BT-549 GDSC1; CTRP2 2.81 7.1367 2.1658 23.8357
HCC38 GDSC1; CTRP2 2.8519 4.8313 2.8012 21.4401
Evsa-T GDSC1 2.8672 4.5913 2.2954 10.3218
MRK-nu-1 GDSC1 3.3025 4.1115 2.9329 3.5369
UACC-893 GDSC1 3.3055 5.0742 2.4546 7.2953
HCC1569 GDSC1 3.3269 6.2198 1.8999 11.5526
MDA-MB-330 GDSC1 3.3669 4.948 2.5691 6.1682
MDA-MB-453 GDSC1; CTRP2 3.3695 9.6176 1.7287 23.8181
YMB-1-E GDSC1 3.4732 7.5383 1.3618 15.0241
EFM-192A GDSC1; CTRP2 3.4911 5.2236 3.4316 17.2124
MCF-7 GDSC1; CTRP2 3.5768 8.1531 2.5828 20.1082
COLO 824 GDSC1 3.6376 5.4506 2.5332 5.539
BT-20 GDSC1; CTRP2 3.7272 5.927 3.5466 16.066
BT-483 GDSC1 3.7966 7.376 1.7004 11.4335
MDA-MB-175-VII GDSC1 3.8093 5.9258 2.4266 5.8422
CAL-148 GDSC1; CTRP2 3.9124 8.6152 2.7285 18.651
MFM-223 GDSC1 4.1512 6.1233 2.5658 3.8727
MDA-MB-231 GDSC1; CTRP2 4.2639 7.2231 3.6883 13.9822
CAL-120 GDSC1 4.3019 8.7865 1.3832 12.1352
MDA-MB-157 GDSC1 4.3632 6.2673 2.6296 2.9479
MDA-MB-436 GDSC1 4.399 6.6061 2.4962 3.8044
EFM-19 GDSC1 4.4278 6.3785 2.6171 2.9032
ZR-75-30 GDSC1; CTRP2 4.57 10.9851 2.2587 18.8198
HCC1395 GDSC1; CTRP2 4.646 6.5759 4.3461 10.4001
HCC1500 GDSC1; CTRP2 4.6565 8.2714 3.6352 13.1653
HCC1428 GDSC1; CTRP2 4.6714 7.392 4.0439 11.499
HDQ-P1 GDSC1; CTRP2 4.7062 8.5611 3.5501 13.3847
HCC202 CTRP2 4.9925 8.3913 3.9102 11.2302
T-47D GDSC1; CTRP2 5.1637 11.9943 2.307 17.2776
UACC-812 GDSC1 5.2211 6.99 2.7594 0.9463
CAMA-1 GDSC1; CTRP2 5.6059 10.6087 3.3873 12.0196
MDA-MB-415 GDSC1 5.8377 7.6048 2.7805 0.4492
JIMT-1 GDSC1; CTRP2 5.9303 9.6803 4.1305 8.2658
HCC1937 GDSC1; CTRP2 6.3232 11.2435 3.6734 9.4249
HCC1419 GDSC1; CTRP2 6.4193 10.0672 4.3363 6.4871
MDA-MB-361 GDSC1; CTRP2 6.7616 12.8463 3.2211 10.4906
BT-474 GDSC1; CTRP2 6.8749 12.6774 3.392 9.6017
KPL-1 CTRP2 6.9413 7.5982 5.8298 0.0968
Hs 578Bst CTRP2 7.1157 13.2906 3.2708 9.6858
BT 239 CTRP2 1.1553 5.5811 0.8278 33.6189
BT 416 CTRP2 1.4133 4.2235 1.3467 31.0752
BT 428 CTRP2 2.3264 4.2625 2.3008 24.8558
BT 228 CTRP2 2.542 4.4617 2.5108 23.4385
BT 145 CTRP2 2.6737 4.3554 2.6552 22.5178
BT164 CTRP2 2.7605 4.648 2.7238 22.0013
BT 482 CTRP2 2.8622 4.5137 2.8407 21.2726
BT 245 CTRP2 2.9334 4.887 2.8812 20.9024
BT 231 CTRP2 3.1349 6.6859 2.6734 21.0239
BT 440 CTRP2 3.1568 6.3399 2.8076 20.4685
BT 159 CTRP2 4.203 5.6091 4.1348 12.501
BT 179 CTRP2 4.3536 6.6336 4.0104 12.5016
BT 498 CTRP2 4.4902 6.5485 4.188 11.4417
BT 422 CTRP2 4.4995 8.7507 3.2576 15.0695
BT 359 CTRP2 4.7998 8.9517 3.4571 13.5338
BT 328 CTRP2 5.304 9.4521 3.69 11.418
BT 112 CTRP2 5.5254 11.7603 2.7432 14.7972
BT 139 CTRP2 5.5576 9.549 3.8715 10.1146
BT 187 CTRP2 5.6104 8.9899 4.196 8.6493
BT 131 CTRP2 5.6173 8.9391 4.2273 8.5034
BT 224 CTRP2 5.7959 8.9466 4.3814 7.4849
BT 333 CTRP2 5.818 13.3076 2.2225 16.2123
BT 330 CTRP2 6.2147 12.5886 2.9131 12.7339
BT 248 CTRP2 6.5232 14.4645 2.2264 14.8188
BT 444 CTRP2 6.8213 8.2043 5.5226 1.0713
BT 216 CTRP2 7.07 11.5564 4.0893 6.432
BT 286 CTRP2 7.1448 15.6162 2.1418 14.0086
BT 271 CTRP2 7.5346 9.1236 5.4984 0.5777
BT147 CTRP2 7.5729 14.5654 2.9809 10.0927
BT 320 CTRP2 7.692 8.7055 5.7182 0.0852
BT 340 CTRP2 7.8189 8.7776 5.7382 0.0494
BT 172 CTRP2 8.0357 15.2178 2.9925 9.3368
BT 232 CTRP2 8.3878 18.4412 1.6739 13.6323
BT 504 CTRP2 8.4589 16.2007 2.8103 9.4132
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 0.9739 3.8973 0.9163 33.9694
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PFSK-1 GDSC1 0.6236 3.2236 0.4091 35.3865
Onda 10 GDSC1 1.0703 4.1489 0.6076 31.408
ONS-76 GDSC1; CTRP2 1.7197 7.6692 0.7991 31.7922
SF539 GDSC1; CTRP2 1.8068 3.7939 1.7902 28.2869
KNS-60 CTRP2 2.0021 4.491 1.94 27.1396
SF268 GDSC1; CTRP2 2.0999 5.9953 1.753 27.4679
D283 Med GDSC1; CTRP2 2.2347 3.2232 2.2346 25.3811
LN-229 GDSC1; CTRP2 2.3238 5.5392 2.11 25.521
SNU-466 CTRP2 2.4156 3.9059 2.4092 24.1971
KS-1 [Human Krukenberg tumour] GDSC1 2.4687 4.9068 1.7571 16.2189
M059J GDSC1 2.5598 7.5647 0.5563 23.9654
D-336MG GDSC1 2.6005 4.3321 2.152 12.6414
M059K CTRP2 2.6785 3.2036 2.6785 22.4243
AM-38 GDSC1; CTRP2 2.9364 6.6508 2.4695 22.3582
GI-1 GDSC1 2.9669 4.9122 2.2339 10.3671
SNU-626 CTRP2 3.1203 8.0963 2.1279 23.0734
SNB-75 GDSC1; CTRP2 3.2331 5.0925 3.1741 18.9291
MOG-G-CCM GDSC1 3.2687 7.3665 1.2777 16.3789
GaMG GDSC1; CTRP2 3.2699 9.6135 1.6296 24.4382
SK-MG-1 GDSC1 3.2959 10.6689 -0.3506 25.69
Onda 11 GDSC1 3.306 6.0851 1.9496 11.2461
LN-405 GDSC1 3.3422 4.2832 2.8809 3.7991
LN-18 GDSC1; CTRP2 3.3719 5.8725 3.1729 18.4962
D-566MG GDSC1 3.4315 4.9537 2.6192 5.5443
MOG-G-UVW GDSC1 3.536 5.1032 2.6276 5.1266
D-423MG GDSC1 3.5829 5.3697 2.5316 5.7265
SNU-738 CTRP2 3.5946 5.611 3.4755 16.7305
D-392MG GDSC1 3.6381 6.0926 2.2152 8.0194
SNU-489 CTRP2 3.6482 4.1786 3.6482 15.964
KNS-81-FD GDSC1 3.6624 5.2636 2.644 4.5998
DK-MG GDSC1; CTRP2 3.7556 5.4987 3.6715 15.5358
Daoy GDSC1; CTRP2 3.7841 8.1524 2.7986 18.7222
YH-13 GDSC1; CTRP2 3.8574 5.0334 3.8397 14.6298
42-MG-BA GDSC1; CTRP2 3.8753 6.6592 3.4848 15.851
KINGS-1 GDSC1 3.95 6.9359 2.0339 8.4344
CAS-1 GDSC1; CTRP2 4.0673 10.3583 2.079 20.7224
D-502MG GDSC1 4.2983 6.6016 2.4353 4.4723
H4 GDSC1 4.4181 10.0847 0.8307 15.4403
KALS-1 GDSC1; CTRP2 4.667 9.5257 3.0552 15.472
Hs 683 GDSC1; CTRP2 4.6686 8.0467 3.7502 12.6739
SNU-1105 CTRP2 4.7205 6.5948 4.4191 9.9121
D-542MG GDSC1 4.9933 6.6354 2.7975 0.9903
SW1088 GDSC1; CTRP2 5.0316 7.9137 4.1732 10.0661
D-247MG GDSC1 5.1226 7.27 2.6016 1.8556
Becker GDSC1; CTRP2 5.2227 11.4496 2.6297 15.8961
CCF-STTG1 CTRP2 5.2719 8.3379 4.2039 9.3685
SF126 GDSC1; CTRP2 5.3261 7.5458 4.6348 7.4745
D-263MG GDSC1 5.3882 6.9001 2.8615 0.4375
SW1783 GDSC1; CTRP2 5.5882 8.4379 4.449 7.6415
U-118MG GDSC1; CTRP2 5.6027 7.9746 4.6903 6.6059
LNZTA3WT4 GDSC1 5.6613 7.2529 2.8392 0.3681
GOS-3 CTRP2 5.7915 11.0434 3.3311 11.8695
KNS-42 GDSC1; CTRP2 5.8245 8.3104 4.7233 5.9924
GMS-10 CTRP2 5.8415 10.2042 3.7931 9.8543
YKG-1 GDSC1; CTRP2 6.0535 10.8101 3.6691 9.9528
A-172 GDSC1; CTRP2 6.1285 12.841 2.7159 13.6842
DBTRG-05MG GDSC1; CTRP2 6.1984 10.6946 3.8463 8.9379
8-MG-BA GDSC1; CTRP2 6.2544 11.1246 3.6771 9.5371
TM-31 CTRP2 6.257 8.0633 5.2062 3.1337
T98G GDSC1; CTRP2 6.351 11.3858 3.6246 9.5756
SF295 GDSC1; CTRP2 6.4958 13.7164 2.5778 13.5258
GB-1 GDSC1; CTRP2 6.7281 10.0279 4.5897 4.9144
U-251MG GDSC1; CTRP2 7.2242 20.3595 -0.1553 21.2997
SNU-201 CTRP2 7.3242 11.3272 4.3784 4.882
KNS-81 CTRP2 7.3916 14.9817 2.6427 11.6981
U-87MG ATCC GDSC1; CTRP2 7.5394 12.4842 3.9692 6.2149
KG-1-C CTRP2 7.9945 8.9254 5.7486 0.0282
NMC-G1 GDSC1; CTRP2 8.2726 13.4724 3.9824 5.1813
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 1.6885 11.4203 -2.138 37.8919
TGBC1TKB GDSC1 5.4295 7.1124 2.8001 0.6185
TGBC24TKB GDSC1 5.8178 7.5328 2.7986 0.4078
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 -1.4177 2.0603 -1.4458 49.7184
HEC-151 CTRP2 -0.1787 1.433 -0.179 41.4601
JHUEM-1 CTRP2 0.4978 3.6973 0.4346 37.1503
JHUEM-7 CTRP2 0.5469 5.067 0.2806 37.4069
HEC-108 CTRP2 1.4382 3.6378 1.4183 30.7534
RL95-2 GDSC1; CTRP2 1.5098 3.1934 1.5057 30.2235
HEC-59 CTRP2 1.6075 5.9002 1.2409 30.7796
HEC-265 CTRP2 1.8198 3.4404 1.815 28.1609
HEC-1-B CTRP2 2.2264 7.8551 1.2735 28.689
AN3-CA GDSC1; CTRP2 2.5359 3.2167 2.5358 23.3744
HEC-6 CTRP2 3.0414 6.6721 2.5765 21.6558
EN GDSC1; CTRP2 3.0528 4.3889 3.044 19.9601
HEC-1-A CTRP2 3.5893 9.3501 2.0715 21.989
MFE-296 GDSC1; CTRP2 3.7138 10.4306 1.6989 23.0057
ESS-1 GDSC1; CTRP2 3.7365 7.2697 3.1103 17.659
HEC-251 CTRP2 3.7845 9.3448 2.2707 20.7325
MFE-319 GDSC1; CTRP2 3.8501 5.8407 3.7021 15.1319
KLE GDSC1; CTRP2 4.5359 10.3034 2.5564 17.7569
JHUEM-3 CTRP2 5.3609 8.555 4.1821 9.2547
HEC-50B CTRP2 5.6051 9.2529 4.0608 9.2246
MFE-280 GDSC1 5.6838 15.7928 -1.0452 21.3441
EFE-184 CTRP2 7.9858 10.8291 5.0106 1.736
Ishikawa (Heraklio) 02 ER- CTRP2 3.7539 5.8182 3.6026 15.7838
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RXF 393L GDSC1 1.8643 4.9462 1.128 23.6788
KTCTL-195 GDSC1 1.8925 7.431 -0.0004 30.0247
KTCTL-140 GDSC1 2.3607 6.0906 1.0911 21.4887
CAL-54 GDSC1; CTRP2 2.3905 5.2449 2.2431 24.8462
769-P GDSC1; CTRP2 2.5398 7.2873 1.8205 25.8728
TUHR10TKB CTRP2 2.9036 5.9759 2.6353 21.8591
TUHR4TKB CTRP2 3.6147 5.8545 3.4422 16.7857
KMRC-3 CTRP2 3.6491 6.6435 3.2452 17.4017
KMRC-1 GDSC1; CTRP2 3.879 4.8822 3.8711 14.4528
A-498 GDSC1 4.0564 6.0943 2.5175 4.4658
KTCTL-1M GDSC1 4.1355 9.8214 0.7479 16.8458
TK-10 GDSC1 4.1825 7.6302 1.8625 9.0327
UO-31 GDSC1; CTRP2 4.352 7.9459 3.4738 14.5851
KTCTL-21 GDSC1 4.3782 10.7136 0.4906 17.6137
LB1047-RCC GDSC1 4.3962 7.976 1.845 8.5571
HA7-RCC GDSC1 4.5766 8.295 1.8148 8.291
BFTC-909 GDSC1; CTRP2 5.2534 8.4494 4.1326 9.7048
BB65-RCC GDSC1 5.3254 7.2436 2.7065 1.0873
SN12C GDSC1 5.4618 7.0769 2.826 0.5094
KTCTL-13 GDSC1 5.4719 7.4577 2.6872 1.0378
786-O GDSC1; CTRP2 5.5284 7.9389 4.639 6.9851
SW13 GDSC1 5.6758 7.269 2.8389 0.3624
SW156 GDSC1 5.7862 7.5654 2.775 0.4912
LB2241-RCC GDSC1 5.8303 7.6442 2.7636 0.5027
KTCTL-26A GDSC1 5.8991 7.8548 2.714 0.6214
A-704 GDSC1 5.9204 7.5323 2.8366 0.2741
ACHN GDSC1; CTRP2 6.0138 9.1245 4.4788 6.6398
Caki-1 GDSC1; CTRP2 6.1148 10.2985 3.9757 8.5559
LB996-RCC GDSC1 6.2407 8.0431 2.7754 0.3002
VMRC-RCZ GDSC1; CTRP2 6.2913 10.6658 3.9361 8.3906
RCC10RGB GDSC1; CTRP2 6.3171 8.7301 4.9215 4.2192
OS-RC-2 GDSC1; CTRP2 6.3574 11.1081 3.7684 8.9675
NCC021 GDSC1 6.4217 8.1011 2.8195 0.1716
KMRC-20 GDSC1; CTRP2 6.4551 8.1335 5.3192 2.3412
Caki-2 CTRP2 6.5982 8.4778 5.2526 2.3989
VMRC-RCW GDSC1; CTRP2 6.6204 9.1881 4.9229 3.7121
KMRC-2 CTRP2 6.6927 13.3511 2.9163 11.8346
SNU-1272 CTRP2 6.8655 11.0894 4.1692 6.4285
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC1; CTRP2 -0.9831 3.5649 -1.1174 46.9844
SNU-175 GDSC1 -0.8699 2.9473 -1.1509 52.3102
HCT 116 GDSC1; CTRP2 0.2481 1.8121 0.2477 38.6172
RKO GDSC1; CTRP2 1.4853 4.3643 1.4069 30.6353
SW48 GDSC1; CTRP2 1.5595 8.1144 0.4618 33.2951
SNU-1040 GDSC1 1.7017 8.5766 -0.7348 33.9658
SNU-C2B GDSC1 1.7244 7.2836 -0.0911 31.2822
MDST8 GDSC1; CTRP2 1.7464 4.725 1.6371 29.0021
SW620 GDSC1; CTRP2 1.9989 7.1237 1.2938 29.3367
COLO205 GDSC1; CTRP2 2.0014 6.0252 1.6374 28.1773
SNU-61 GDSC1; CTRP2 2.0498 8.539 0.8187 30.6713
SNU-C2A CTRP2 2.0555 6.9952 1.3989 28.8103
SNU-1033 CTRP2 2.1427 9.0718 0.6994 30.7352
SW626 GDSC1 2.1921 9.8091 -0.8853 32.2723
SNU-C1 GDSC1; CTRP2 2.2022 3.7385 2.1965 25.6164
COLO201 CTRP2 2.2953 5.9077 1.9894 26.0316
NCI-H747 GDSC1; CTRP2 2.538 7.5418 1.7252 26.2111
SK-CO-1 CTRP2 2.5718 4.8866 2.4966 23.3897
LS180 GDSC1; CTRP2 2.623 6.4477 2.1931 24.2993
OUMS-23 CTRP2 2.6986 5.0747 2.6047 22.6096
LS123 GDSC1; CTRP2 2.7607 6.8099 2.2259 23.7656
SNU-407 GDSC1; CTRP2 2.7706 7.4413 2.0121 24.5047
LS411N GDSC1; CTRP2 2.9365 6.8538 2.4016 22.605
KM12 GDSC1; CTRP2 3.1608 6.5803 2.7363 20.7168
HCC2998 GDSC1 3.2368 7.2434 1.3122 16.2565
NCI-H508 CTRP2 3.2409 6.4859 2.8538 20.0487
SNU-C5 GDSC1; CTRP2 3.3566 7.4302 2.6433 20.4937
CCK-81 GDSC1; CTRP2 3.509 6.1037 3.2611 17.76
CaR-1 GDSC1 3.5803 6.3401 2.0466 9.5218
LS513 GDSC1; CTRP2 3.6523 5.564 3.5476 16.2958
LoVo GDSC1; CTRP2 3.7015 6.3937 3.3843 16.7334
T84 GDSC1; CTRP2 3.8038 6.8486 3.3404 16.5983
GP5d GDSC1 3.9239 10.2567 0.3668 19.8007
HT115 GDSC1; CTRP2 4.141 5.3685 4.1052 12.8018
SW837 GDSC1 4.3654 9.1507 1.2508 12.8553
GP2d CTRP2 4.8374 7.2815 4.2631 10.1984
COLO 678 GDSC1; CTRP2 4.8633 10.0412 2.9929 15.2601
COLO 320 CTRP2 5.0102 10.9796 2.6696 16.2112
COLO 320HSR GDSC1 5.0201 6.9203 2.6957 1.4733
RCM-1 [Human ESC] GDSC1; CTRP2 5.0895 7.3847 4.4746 8.7072
DLD-1 CTRP2 5.1617 7.5356 4.4777 8.514
C2BBe1 GDSC1; CTRP2 5.1653 12.8487 1.8844 18.8541
SNU-503 CTRP2 5.2172 9.3333 3.6682 11.7017
HT-55 GDSC1; CTRP2 5.3349 7.3836 4.7197 7.1081
SW1417 GDSC1; CTRP2 5.3688 8.1964 4.364 8.4852
NCI-H716 GDSC1; CTRP2 5.3911 9.2503 3.869 10.4848
CL-11 GDSC1; CTRP2 5.4402 9.5547 3.7634 10.8158
LS1034 GDSC1; CTRP2 5.4637 9.1391 3.99 9.8237
SNU-C4 CTRP2 5.5244 7.9827 4.6139 7.0981
SW1116 GDSC1 5.696 7.3617 2.8136 0.423
SW1463 GDSC1 5.7428 7.2594 2.8669 0.2676
HCT 15 GDSC1; CTRP2 5.8083 7.3457 5.1878 4.0837
SW948 GDSC1; CTRP2 5.885 8.4389 4.7118 5.9167
CW-2 GDSC1; CTRP2 6.1011 9.5643 4.3315 7.0905
HCC-56 CTRP2 6.3019 7.3215 5.6056 1.4029
HT-29 GDSC1; CTRP2 6.612 13.175 2.9404 11.8843
HCT 8 CTRP2 7.6387 9.7307 5.2992 1.0895
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -2.0389 3.7987 -2.6582 60.9549
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 GDSC1; CTRP2 -13.5649 -1.3993 -13.8767 87.7113
HuH-6 CTRP2 0.4551 4.4282 0.2977 46.7815
SNU-182 CTRP2 1.6712 3.23 1.6683 29.1445
Hep-G2 CTRP2 1.8176 8.1993 0.7052 31.751
JHH-1 GDSC1; CTRP2 2.3828 4.9675 2.2826 24.7344
SNU-423 GDSC1; CTRP2 2.8289 4.6945 2.7913 21.5486
SNU-387 GDSC1; CTRP2 3.1281 4.8132 3.0947 19.5412
SK-HEP-1 GDSC1; CTRP2 3.8673 4.7635 3.8634 14.5169
JHH-6 GDSC1; CTRP2 3.9232 5.9442 3.7561 14.7134
HLF CTRP2 4.1953 7.5871 3.4663 15.0294
SNU-886 CTRP2 4.385 5.7436 4.3058 11.3275
PLC/PRF/5 CTRP2 4.6875 7.206 4.14 11.0794
SNU-878 CTRP2 4.8657 6.2696 4.6901 8.4776
Hep-G2/C3A GDSC1 4.9524 6.2441 2.9295 0.4709
SNU-475 GDSC1; CTRP2 5.0054 8.745 3.7539 11.8373
JHH-7 GDSC1 5.023 9.4905 1.5421 9.0586
Hep 3B2.1-7 GDSC1; CTRP2 5.0924 7.7277 4.3198 9.3233
Huh-7 GDSC1 5.6433 7.0784 2.8936 0.2425
HuH-1 GDSC1; CTRP2 5.6609 7.9114 4.7747 6.1263
SNU-761 CTRP2 5.6786 9.3484 4.0785 8.9958
JHH-4 GDSC1; CTRP2 5.8847 7.9101 4.9753 4.8118
Li-7 CTRP2 5.9053 21.7074 -1.9033 27.9704
HLE GDSC1 6.2793 8.199 2.7353 0.3781
JHH-2 GDSC1; CTRP2 6.2987 10.1523 4.1983 7.2809
SNU-449 GDSC1; CTRP2 7.662 10.4027 5.02 2.0085
JHH-5 CTRP2 9.2036 18.4099 2.2549 10.4006
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 213 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H510A GDSC1; CTRP2 -3.8854 11.6055 -6.6924 57.81
SBC-3 GDSC1 -2.7729 1.8273 -2.9859 69.0016
NCI-H847 GDSC1 -2.0011 4.1252 -2.7172 60.3113
HCC33 GDSC1 -1.5567 1.5792 -1.6452 60.0309
DV-90 CTRP2 -1.2599 4.9199 -1.6505 48.8356
COR-L311 GDSC1 -0.8986 2.2027 -1.0308 52.8295
NCI-H526 GDSC1; CTRP2 -0.4644 3.288 -0.5383 43.5333
NCI-H1694 GDSC1; CTRP2 -0.4192 3.7536 -0.5414 43.3353
LCLC-97TM1 GDSC1; CTRP2 -0.3205 5.6846 -0.8069 43.3421
COR-L23 GDSC1 -0.2856 5.2581 -1.2615 47.0474
NCI-H358 GDSC1; CTRP2 -0.2182 3.3406 -0.2846 41.8971
NCI-H810 GDSC1; CTRP2 -0.2165 4.3465 -0.4109 42.1704
SBC-1 GDSC1 -0.1493 8.3885 -2.4579 47.0756
IST-SL2 GDSC1 -0.0681 4.7983 -0.8544 44.8485
Lu-139 GDSC1 0.0583 5.7255 -1.0835 44.3148
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 0.1074 4.2994 -0.0553 39.998
EMC-BAC-2 GDSC1 0.1495 3.612 -0.2165 41.5842
HCC44 GDSC1; CTRP2 0.1896 5.254 -0.148 39.8847
CPC-N GDSC1 0.1916 4.9974 -0.652 42.4908
NCI-H64 GDSC1 0.2007 1.6292 0.1906 39.5016
LC-2/ad GDSC1 0.2253 6.1614 -1.0908 43.198
EPLC-272H GDSC1; CTRP2 0.3229 3.1689 0.292 38.2142
IST-SL1 GDSC1 0.3395 5.3232 -0.6236 41.3739
DMS 273 GDSC1; CTRP2 0.3509 6.1156 -0.1886 39.3259
NCI-H1437 GDSC1 0.3514 4.6823 -0.3612 40.5325
NCI-H209 GDSC1 0.3648 3.6623 0.0032 39.1326
NCI-H1975 GDSC1; CTRP2 0.3986 4.3019 0.2564 38.0354
MOR/CPR CTRP2 0.4481 2.5765 0.4421 37.3032
NCI-H211 GDSC1; CTRP2 0.6143 3.315 0.585 36.2707
NCI-H748 GDSC1 0.6531 4.2739 0.113 36.6277
NCI-H520 GDSC1; CTRP2 0.7266 4.9271 0.5034 36.1134
COR-L51 CTRP2 0.8635 4.9917 0.639 35.2192
NCI-H1836 GDSC1 0.9038 5.368 -0.0489 35.6962
COR-L303 GDSC1 0.9114 7.3006 -0.8974 38.5779
NCI-H446 GDSC1; CTRP2 0.958 4.1922 0.8679 34.1794
NCI-H1876 GDSC1 1.2008 5.6048 0.1581 32.9753
NCI-H1648 GDSC1 1.2063 10.3885 -2.0804 39.8389
RERF-LC-KJ GDSC1 1.2153 3.4878 0.9825 28.2529
NCI-H2141 GDSC1; CTRP2 1.3029 7.6793 0.3466 34.4816
LCLC-103H GDSC1; CTRP2 1.3135 5.1753 1.0902 32.2517
NCI-H2171 GDSC1; CTRP2 1.4222 6.9135 0.7386 32.9673
DMS 114 GDSC1; CTRP2 1.4965 5.8619 1.1297 31.5087
CAL-12T GDSC1; CTRP2 1.5727 6.7245 0.963 31.7801
NCI-H1734 GDSC1; CTRP2 1.6236 5.8883 1.2615 30.6592
Lu-99 CTRP2 1.6648 6.4002 1.1631 30.8426
NCI-H3122 GDSC1 1.7224 10.4744 -1.6419 36.5918
NCI-H2110 GDSC1; CTRP2 1.7849 3.7232 1.7709 28.4239
Ms-1 GDSC1 1.821 6.0717 0.5747 27.3712
NCI-H2135 GDSC1 1.8215 6.1392 0.5438 27.5462
NCI-H2030 GDSC1; CTRP2 1.8373 5.1296 1.6665 28.6059
NCI-H2227 GDSC1 1.9681 13.6656 -2.9966 38.4817
NCI-H1666 GDSC1; CTRP2 1.9776 6.3633 1.5151 28.6679
HCC2108 CTRP2 2.0032 5.9824 1.651 28.125
NCI-H187 GDSC1 2.0078 7.3558 0.1454 28.7514
NCI-H1581 GDSC1; CTRP2 2.019 5.0221 1.8823 27.2815
HCC78 GDSC1; CTRP2 2.068 6.661 1.5221 28.3573
NCI-H2087 GDSC1; CTRP2 2.0907 6.6373 1.5542 28.1768
NCI-H82 GDSC1 2.1188 4.9037 1.407 20.4555
NCI-H1184 CTRP2 2.1383 6.5257 1.641 27.7311
NCI-H2869 GDSC1 2.2428 7.8049 0.1472 27.6328
NCI-H647 GDSC1; CTRP2 2.2444 6.686 1.706 27.1762
HCC827 GDSC1; CTRP2 2.2611 5.2319 2.1057 25.735
NCI-H2373 GDSC1 2.4001 6.7494 0.8092 23.1453
NCI-H838 GDSC1; CTRP2 2.5053 3.7566 2.503 23.5858
ABC-1 GDSC1 2.5183 11.3139 -1.3409 32.462
SK-MES-1 GDSC1; CTRP2 2.5188 6.2954 2.1254 24.8589
VMRC-LCD CTRP2 2.5209 8.5619 1.3068 27.6826
PC-14 GDSC1; CTRP2 2.5475 5.7075 2.3146 24.101
NCI-H1105 CTRP2 2.6092 3.2158 2.6092 22.8858
NCI-H1703 GDSC1; CTRP2 2.6263 6.6131 2.1446 24.4624
NCI-H1385 CTRP2 2.6412 11.6254 0.0816 30.9629
LK2 CTRP2 2.6703 4.9809 2.5886 22.7559
Calu-6 GDSC1; CTRP2 2.7326 7.3663 1.9992 24.6634
NCI-H2595 GDSC1 2.7747 5.7865 1.6279 15.817
NCI-H1048 GDSC1 2.7772 7.359 0.8539 21.2046
NCI-H1869 GDSC1; CTRP2 2.8198 5.499 2.6578 22.0397
NCI-H661 GDSC1; CTRP2 2.8728 5.477 2.72 21.6546
PaCa-3 GDSC1 2.8885 8.9802 0.1455 24.8495
NCI-H292 GDSC1; CTRP2 2.8894 5.6877 2.6917 21.7025
LC-1F CTRP2 2.9456 7.7101 2.0969 23.6873
NCI-H1915 GDSC1; CTRP2 2.949 8.7998 1.6554 25.2482
NCI-H1341 CTRP2 2.967 6.2449 2.6292 21.6876
NCI-H1436 GDSC1 2.9698 5.5938 1.901 12.9307
NCI-H2286 CTRP2 2.994 8.7016 1.7439 24.8104
NCI-H650 GDSC1; CTRP2 3.0013 5.1181 2.9227 20.5408
NCI-H2795 GDSC1 3.0178 3.7743 2.8254 5.5974
HCC1833 CTRP2 3.0285 12.2713 0.1624 29.6611
NCI-H2126 CTRP2 3.0456 4.1511 3.043 19.9873
HCC95 CTRP2 3.0781 5.735 2.8861 20.4264
NCI-H2106 CTRP2 3.0989 8.1888 2.0676 23.3537
NCI-H1304 GDSC1 3.1036 8.6176 0.5121 21.9622
NCI-H1944 GDSC1; CTRP2 3.1476 10.9941 0.8768 27.2587
NCI-H1568 GDSC1; CTRP2 3.148 3.8373 3.1479 19.2964
NCI-H226 GDSC1; CTRP2 3.1696 7.853 2.2783 22.3815
NCI-H1563 GDSC1; CTRP2 3.1738 4.9222 3.1318 19.2662
ChaGo-K-1 GDSC1; CTRP2 3.1936 4.5593 3.181 19.0345
LK-2 GDSC1 3.2119 5.7667 2.0286 10.9869
SK-LU-1 GDSC1; CTRP2 3.2129 6.3603 2.8626 20.0998
NCI-H2029 GDSC1; CTRP2 3.218 5.0192 3.1675 19.0007
COR-L88 GDSC1 3.2852 5.2743 2.3373 8.2942
NCI-H1092 GDSC1; CTRP2 3.2889 8.1607 2.2787 22.0439
NCI-H2009 GDSC1; CTRP2 3.332 4.8592 3.3045 18.1629
NCI-H290 GDSC1 3.3344 4.3267 2.8526 4.051
LXF 289 GDSC1; CTRP2 3.3597 7.0485 2.7899 19.9369
NCI-H1993 GDSC1 3.3608 4.7734 2.6514 5.5414
NCI-H345 GDSC1 3.4236 6.2031 1.9885 10.5176
NCI-H2081 GDSC1; CTRP2 3.4333 7.6267 2.6478 20.2602
NCI-H2369 GDSC1 3.438 4.3735 2.914 3.202
NCI-H2347 GDSC1 3.4495 6.1 2.0612 9.8615
LUDLU-1 CTRP2 3.4567 6.9796 2.9192 19.1747
HCC2279 CTRP2 3.4615 4.8682 3.4392 17.2826
HCC1438 CTRP2 3.4672 8.5438 2.3024 21.4627
Lu-135 GDSC1 3.4903 10.6884 -0.1988 24.2707
SW1573 GDSC1 3.5089 4.8445 2.7351 4.372
NCI-H2461 GDSC1 3.5211 4.7701 2.7815 3.9686
SW1271 GDSC1; CTRP2 3.5622 10.1183 1.6938 23.4231
EMC-BAC-1 GDSC1 3.5797 8.4713 0.9824 17.2436
RERF-LC-A1 CTRP2 3.6047 5.6801 3.4718 16.712
NCI-H23 GDSC1; CTRP2 3.6082 5.3805 3.5331 16.4861
HCC1195 CTRP2 3.6169 6.6236 3.2171 17.6004
NCI-H841 GDSC1; CTRP2 3.634 5.624 3.5156 16.4655
NCI-H1339 CTRP2 3.6568 5.3586 3.5888 16.1378
Lu-165 GDSC1 3.6597 4.8976 2.8214 3.2368
NCI-H2122 GDSC1; CTRP2 3.6753 8.1561 2.6841 19.4546
Sq-1 CTRP2 3.6797 7.1457 3.0971 17.8693
NCI-H522 GDSC1; CTRP2 3.6847 5.9069 3.5054 16.344
NCI-H1395 CTRP2 3.6944 9.1664 2.2606 21.0079
NCI-H2228 GDSC1; CTRP2 3.7072 7.0805 3.1512 17.587
NCI-H1299 GDSC1; CTRP2 3.7079 5.7521 3.568 16.0493
COR-L95 GDSC1; CTRP2 3.7303 9.1751 2.293 20.7915
HCC1588 CTRP2 3.7727 7.1185 3.2069 17.1907
NCI-H322 CTRP2 3.7809 5.9586 3.5971 15.7202
NCI-H1623 GDSC1; CTRP2 3.781 6.4565 3.4505 16.2542
COR-L321 GDSC1 3.7994 11.9316 -0.568 24.8801
NCI-H727 GDSC1; CTRP2 3.8259 8.2292 2.8089 18.5705
UMC-11 GDSC1 3.8388 9.2504 0.801 17.503
HCC4006 CTRP2 3.8519 6.476 3.5212 15.7842
EBC-1 GDSC1; CTRP2 3.87 9.2094 2.4183 19.9515
A-427 GDSC1 3.8842 6.0614 2.4144 5.7174
NCI-H2804 GDSC1 3.8895 6.0203 2.4381 5.52
NCI-H1651 GDSC1; CTRP2 3.9287 7.268 3.3154 16.3407
NCI-H69 GDSC1; CTRP2 3.9727 12.8152 0.8083 25.3082
HCC366 CTRP2 3.9927 9.1686 2.56 19.0919
RERF-LC-MS GDSC1; CTRP2 4.039 5.3063 4.0044 13.4769
Lu-65 GDSC1; CTRP2 4.0408 9.8717 2.2822 20.0285
COLO 699 CTRP2 4.1585 10.5103 2.0952 20.4341
NCI-H2405 GDSC1; CTRP2 4.1845 8.3211 3.1367 16.3491
NCI-H524 GDSC1 4.1889 14.8013 -1.6881 27.8746
COLO 668 GDSC1; CTRP2 4.2054 8.2063 3.2089 16.0109
HOP-62 GDSC1; CTRP2 4.2616 12.8429 1.0651 23.78
SBC-5 GDSC1; CTRP2 4.2768 5.2532 4.2605 11.8306
NCI-H2196 GDSC1; CTRP2 4.3036 7.9258 3.433 14.8727
NCI-H1688 GDSC1 4.3261 8.2672 1.6545 10.1379
LC-1/sq GDSC1 4.3465 10.0068 0.8158 15.7542
NCI-H2591 GDSC1 4.3705 7.1622 2.2176 5.8888
NCI-H2170 GDSC1; CTRP2 4.4157 6.6814 4.0598 12.1377
Calu-3 GDSC1; CTRP2 4.4289 7.1629 3.8868 12.7635
DMS 79 GDSC1; CTRP2 4.4328 10.8957 2.1726 19.4727
NCI-H1573 GDSC1 4.4486 6.4466 2.5985 2.9883
NCI-H1770 GDSC1 4.4502 6.0898 2.7574 1.9368
NCI-H2023 GDSC1; CTRP2 4.4776 8.2568 3.4625 14.3067
NCI-H1838 GDSC1; CTRP2 4.4788 7.6908 3.7158 13.2988
Lu-134-A GDSC1 4.4812 12.3309 -0.2315 21.1294
NCI-H513 GDSC1 4.5057 7.8391 1.9851 7.244
NCI-H596 GDSC1 4.5123 12.5053 -0.2943 21.3356
NCI-H3255 GDSC1 4.5944 9.1892 1.396 11.1956
NCI-H1155 GDSC1; CTRP2 4.6322 7.0242 4.1575 11.1606
NCI-H1650 GDSC1; CTRP2 4.6521 7.3853 4.0269 11.6172
NCI-H460 GDSC1; CTRP2 4.7474 7.9074 3.8928 11.9034
NCI-H2722 GDSC1 4.7539 6.4327 2.7675 1.4219
NCI-H1435 GDSC1; CTRP2 4.7621 9.9734 2.9303 15.7463
NCI-H1373 CTRP2 4.7709 10.5004 2.6828 16.7073
NCI-H720 GDSC1 4.8049 6.1879 2.8891 0.7505
A-549 GDSC1; CTRP2 4.8342 7.4632 4.1802 10.5349
RERF-LC-Ad2 CTRP2 4.8635 8.9263 3.5307 13.0831
COR-L105 GDSC1; CTRP2 4.9256 10.9541 2.6045 16.6588
NCI-H2342 GDSC1; CTRP2 5.0431 7.975 4.1559 10.1083
Lu-99A GDSC1 5.1065 7.3795 2.548 2.1847
NCI-H1693 GDSC1; CTRP2 5.123 8.7898 3.8444 11.1916
NCI-H2803 GDSC1 5.1281 6.619 2.8613 0.6011
RERF-LC-Sq1 GDSC1 5.1523 12.8317 0.019 17.9113
NCI-H441 GDSC1; CTRP2 5.2214 8.0277 4.3046 9.0733
NCI-H322M GDSC1 5.2706 9.3631 1.7586 7.0074
EKVX GDSC1; CTRP2 5.2797 9.4874 3.6504 11.6354
NCI-H1792 GDSC1; CTRP2 5.4305 8.5715 4.2387 8.8639
HCC15 GDSC1; CTRP2 5.5001 9.5455 3.8218 10.4442
NCI-H1755 GDSC1; CTRP2 5.5258 7.5872 4.8074 6.2954
NCI-H1781 GDSC1 5.5428 7.1012 2.8485 0.3972
LOU-NH91 GDSC1; CTRP2 5.5897 8.0354 4.6485 6.8081
SHP-77 GDSC1; CTRP2 5.6246 8.4557 4.4732 7.4618
LC-1/sq-SF CTRP2 5.6704 9.0116 4.2387 8.3433
NCI-H1355 GDSC1; CTRP2 5.6725 8.0979 4.6933 6.4401
NCI-H2818 GDSC1 5.6773 7.6614 2.6963 0.8319
NCI-H2444 GDSC1; CTRP2 5.6906 8.9218 4.3011 8.04
RERF-LC-Ad1 CTRP2 5.732 8.9286 4.3344 7.814
NCI-H889 CTRP2 5.7905 7.6959 4.9986 4.912
NCI-H196 GDSC1; CTRP2 5.7989 10.9038 3.4071 11.5416
DMS 53 GDSC1; CTRP2 5.819 9.0895 4.3301 7.6524
NCI-H2085 GDSC1; CTRP2 5.8371 11.0075 3.388 11.5432
NCI-H1793 GDSC1; CTRP2 5.8575 8.0624 4.8757 5.2857
NCI-H2731 GDSC1 6.1703 8.0167 2.7591 0.3625
NCI-H2172 GDSC1; CTRP2 6.1726 7.3653 5.4875 2.1046
BEN GDSC1; CTRP2 6.2471 8.1238 5.1684 3.3091
KNS-62 CTRP2 6.3183 11.0935 3.7443 9.1394
T3M-10 CTRP2 6.4997 8.303 5.2684 2.4809
HCC2935 CTRP2 6.6515 11.8657 3.6229 9.0434
Calu-1 CTRP2 7.3169 11.7219 4.1834 5.6768
NCI-H2291 GDSC1; CTRP2 7.4875 10.4582 4.8927 2.6623
HOP-92 GDSC1; CTRP2 7.5721 14.5425 2.9915 10.0526
IA-LM GDSC1; CTRP2 7.5897 9.4407 5.3957 0.8316
HCC1171 CTRP2 7.6964 11.5606 4.5115 3.8647
DMS 454 CTRP2 8.113 10.6908 5.1347 1.237
Hs 888.Lu CTRP2 5.2781 11.0695 2.8678 14.8303
⏷ Show the Full List of 213 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 0.8162 7.7975 -1.2218 39.9435
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.5648 7.0081 -0.2241 38.5667
A2780 GDSC1; CTRP2 -2.2544 4.9617 -2.7413 54.3039
COV434 CTRP2 -0.7856 2.9065 -0.8423 45.6072
MCAS CTRP2 -0.5025 2.9775 -0.5524 43.7336
OC 314 GDSC1; CTRP2 -0.2457 3.8175 -0.365 42.1993
ONCO-DG-1 CTRP2 0.1544 7.0796 -0.6933 41.1214
COV644 CTRP2 0.9171 4.3229 0.8076 34.5125
OVK18 GDSC1; CTRP2 1.0443 4.1848 0.9604 33.5862
Caov-3 GDSC1; CTRP2 1.4271 7.0648 0.6939 33.0822
JHOC-5 CTRP2 1.5603 4.4516 1.4759 30.1566
IGROV-1 GDSC1; CTRP2 1.5846 7.8863 0.5741 32.8961
HEY A8 CTRP2 1.6781 5.2463 1.4711 29.7852
SNU-8 CTRP2 1.9107 4.4798 1.8445 27.7623
OVCAR-4 GDSC1; CTRP2 2.1099 6.8965 1.491 28.3301
SNU-119 CTRP2 2.1473 5.4043 1.9475 26.6455
TOV-112D GDSC1; CTRP2 2.4014 7.9223 1.4347 27.6176
EFO-27 GDSC1; CTRP2 2.9705 8.2363 1.9131 24.2769
ES-2 GDSC1 3.3336 4.4176 2.8065 4.4167
DOV13 GDSC1; CTRP2 3.5124 6.2644 3.2181 17.906
OAW28 GDSC1; CTRP2 3.6234 5.6041 3.5082 16.5252
OVTOKO GDSC1; CTRP2 3.6603 5.8286 3.4982 16.4454
OVSAHO CTRP2 3.769 8.9989 2.4114 20.2426
SNU-840 CTRP2 3.9695 8.3712 2.8949 17.8564
OV7 CTRP2 4.1807 12.5404 1.1371 23.7422
OVKATE GDSC1 4.2069 8.6868 1.3623 12.5692
OVCAR-8 GDSC1; CTRP2 4.2359 8.7761 2.9831 16.8216
OVISE GDSC1; CTRP2 4.3814 10.72 2.2085 19.4618
COV362 CTRP2 4.4717 7.4639 3.8062 12.9621
ES2 CTRP2 4.5895 7.0968 4.0829 11.5659
OVCAR-5 GDSC1; CTRP2 4.7517 12.3161 1.7753 20.1833
TYK-nu GDSC1; CTRP2 4.8151 7.3395 4.215 10.4467
Kuramochi GDSC1; CTRP2 4.8239 11.3763 2.3036 18.0559
TOV-21G GDSC1; CTRP2 4.8247 7.2483 4.2644 10.2264
Caov-4 GDSC1 4.8489 8.8201 1.7456 8.0857
OAW42 GDSC1; CTRP2 5.2014 8.2412 4.1833 9.6175
OVCAR-3 GDSC1 5.4376 7.2749 2.7425 0.8332
JHOM-1 CTRP2 5.4589 8.9954 4.0564 9.5582
RMG-I GDSC1; CTRP2 5.5191 19.34 -1.0461 26.8402
SK-OV-3 GDSC1; CTRP2 5.6403 11.364 3.0407 13.3641
JHOS-2 GDSC1; CTRP2 6.1036 9.9149 4.1583 7.8125
OV56 GDSC1; CTRP2 6.2009 7.1657 5.6082 1.5526
EFO-21 GDSC1; CTRP2 6.7133 14.0328 2.593 13.0673
OV-90 GDSC1; CTRP2 7.0812 17.5407 1.1358 17.6453
FU-OV-1 GDSC1; CTRP2 8.1401 23.1982 -0.8547 21.5821
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 2.5004 4.8189 2.4294 23.8512
H-STS CTRP2 2.8355 3.3173 2.8355 21.3785
SYO-1 CTRP2 7.0675 20.6861 -0.4423 22.358
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 2.7266 4.2093 2.7167 22.1368
Aska-SS CTRP2 2.8575 6.2329 2.5131 22.4382
TE 617.T CTRP2 -0.0515 4.4939 -0.2581 41.1331
KYM-1 GDSC1; CTRP2 0.0018 2.1378 -0.0021 40.2689
EW-8 GDSC1 0.0135 2.735 -0.1429 42.4354
A-204 GDSC1; CTRP2 0.1438 10.7477 -2.0909 43.075
TTC-709 CTRP2 0.1885 8.1126 -1.0102 41.5094
BT-12 CTRP2 0.6411 0.9178 0.6411 35.9972
G-401 GDSC1; CTRP2 0.6871 5.5663 0.3211 36.77
Tm87-16 CTRP2 0.8011 6.2854 0.2546 36.5224
G-402 GDSC1; CTRP2 1.1285 6.748 0.4721 34.7507
SW982 GDSC1; CTRP2 1.3478 5.7732 0.9903 32.4531
Rh41 GDSC1; CTRP2 1.5486 3.5219 1.5366 29.9916
TE 441.T GDSC1; CTRP2 1.9576 3.6989 1.9485 27.2573
Rh30 GDSC1 2.265 7.0054 0.558 25.2909
Hs 633.T GDSC1 2.7389 4.5238 2.2025 11.6106
MES-SA GDSC1; CTRP2 3.0498 4.3911 3.0409 19.9801
RD GDSC1; CTRP2 3.2234 7.1218 2.6165 20.9753
VA-ES-BJ GDSC1 3.253 5.2691 2.3124 8.6111
MFH-ino GDSC1 3.4484 4.65 2.7844 4.1856
RKN GDSC1; CTRP2 3.4988 6.6243 3.0888 18.4212
HT-1080 GDSC1; CTRP2 3.6243 8.9663 2.2788 21.1262
GCT GDSC1; CTRP2 3.7553 6.743 3.3258 16.7925
Hs 729.T CTRP2 3.9468 6.853 3.4928 15.6152
BT-16 CTRP2 4.0011 8.0802 3.0542 17.1534
SW872 GDSC1 4.3724 6.0506 2.7319 2.2394
SW684 GDSC1 4.6097 6.5336 2.6504 2.3446
SK-UT-1 GDSC1; CTRP2 5.2027 9.8514 3.4008 12.8336
SK-LMS-1 GDSC1; CTRP2 6.7887 12.4055 3.4608 9.4694
Rh18 CTRP2 8.221 9.5062 5.6319 0.0932
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 8.0177 9.5753 5.5314 0.3273
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1; CTRP2 1.8506 4.1852 1.8104 28.0745
MSTO-211H GDSC1; CTRP2 2.2546 4.0347 2.2396 25.2983
NCI-H2452 GDSC1; CTRP2 4.0093 6.1486 3.7942 14.3141
JL-1 CTRP2 4.2687 6.434 3.9877 12.8322
MPP 89 GDSC1; CTRP2 5.0299 6.9718 4.5956 8.3813
NCI-H2052 GDSC1; CTRP2 5.3342 7.4807 4.6734 7.2981
ACC-MESO-1 CTRP2 6.4422 9.1172 4.8256 4.4046
IST-Mes1 GDSC1; CTRP2 8.1268 16.7755 2.2997 11.8084
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; CTRP2 1.9238 7.4564 1.0958 30.215
PC-3 GDSC1 2.7501 6.8646 1.0744 19.8705
VCaP GDSC1; CTRP2 3.0486 5.9086 2.811 20.7849
22Rv1 GDSC1; CTRP2 3.1613 8.7656 1.8904 23.8175
DU145 GDSC1; CTRP2 4.9657 7.0006 4.5166 8.8619
PaCa-3 CTRP2 6.5036 9.7735 4.5473 5.4599
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 1.427 3.0089 1.4246 30.7697
A-253 GDSC1; CTRP2 4.8901 9.2451 3.4034 13.5379
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 0.2192 7.1565 -1.5306 43.9801
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GSS CTRP2 0.5049 5.5118 0.1356 37.9487
SNU-1 GDSC1; CTRP2 0.6103 6.3801 0.0191 37.8324
RF-48 GDSC1 0.6914 6.0099 -0.5429 38.8296
HGC-27 GDSC1; CTRP2 0.8124 4.0171 0.7338 35.1098
ECC10 GDSC1; CTRP2 1.1463 5.0911 0.9258 33.3459
IM95 GDSC1; CTRP2 1.4069 7.2027 0.6256 33.3493
SNU-620 CTRP2 1.4806 4.2673 1.413 30.6305
Fu97 GDSC1; CTRP2 1.5087 3.4493 1.4983 30.2521
SNU-5 GDSC1; CTRP2 1.7618 4.8906 1.6276 28.9839
SNU-719 CTRP2 1.9551 7.9297 0.9551 30.5556
SNU-216 CTRP2 2.0395 7.3587 1.2555 29.3329
SNU-16 GDSC1; CTRP2 2.105 3.1121 2.1048 26.2454
23132/87 GDSC1; CTRP2 2.3944 4.8231 2.3159 24.5828
SNU-668 CTRP2 2.5018 4.0139 2.4938 23.6281
NUGC-3 GDSC1; CTRP2 2.5559 6.8812 1.9798 25.2621
AGS GDSC1; CTRP2 2.6214 4.3859 2.5991 22.8791
SH-10-TC CTRP2 2.702 3.1291 2.702 22.2673
HuG1-N CTRP2 2.7736 8.5053 1.5956 25.9619
SCH GDSC1 2.9309 3.6222 2.7996 6.2211
NUGC-4 GDSC1; CTRP2 2.9552 8.722 1.6949 25.093
TMK-1 GDSC1 3.0701 6.172 1.7032 14.0358
HSC-39 GDSC1 3.1856 9.6297 0.0761 24.037
OCUM-1 GDSC1; CTRP2 3.2727 8.5719 2.0888 22.7881
RERF-GC-1B GDSC1 3.4183 6.6852 1.7431 12.4159
NCI-N87 GDSC1; CTRP2 3.6038 7.5148 2.8731 18.9314
ECC12 CTRP2 3.6164 5.0714 3.5834 16.2872
MKN74 CTRP2 3.7629 9.9855 1.9546 21.9593
SNU-601 CTRP2 3.9978 9.1957 2.5527 19.1069
GCIY GDSC1 4.1849 6.6412 2.3424 5.4394
Hs 746.T GDSC1; CTRP2 4.3684 7.9873 3.4723 14.5483
LMSU CTRP2 4.5184 6.6421 4.1846 11.3736
MKN28 GDSC1 4.5737 9.6593 1.1527 12.8991
MKN7 GDSC1; CTRP2 4.9332 6.8352 4.5516 8.813
TGBC11TKB GDSC1 5.8496 7.7542 2.7312 0.5936
KATO III CTRP2 6.8687 10.0812 4.6648 4.3878
MKN45 GDSC1; CTRP2 7.2192 8.544 5.585 0.5351
MKN1 GDSC1; CTRP2 8.8281 17.8251 2.2815 10.8309
KE-39 CTRP2 10.49 21.7241 1.5276 11.1746
SNG-M GDSC1; CTRP2 1.0446 3.6107 1.0127 33.4147
SNU-685 CTRP2 4.8311 7.4516 4.1821 10.5355
SNU-1077 CTRP2 6.3199 11.1636 3.7106 9.2766
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 -1.0036 0.8274 -1.0124 54.4207
TT GDSC1; CTRP2 0.7652 3.0875 0.751 35.2177
8305C GDSC1; CTRP2 1.7563 3.0532 1.7555 28.5704
SW579 CTRP2 2.3209 5.7777 2.0504 25.7382
8505C GDSC1; CTRP2 2.5325 5.9162 2.246 24.3893
B-CPAP GDSC1; CTRP2 2.7001 3.9669 2.6966 22.2917
FTC-238 CTRP2 2.7019 7.2659 2.0028 24.7418
KMH-2 GDSC1 3.1113 5.0634 2.2908 9.3311
CAL-62 GDSC1; CTRP2 3.4433 6.971 2.908 19.2554
CGTH-W-1 GDSC1; CTRP2 3.5189 6.9413 3.0001 18.6929
BHT-101 GDSC1; CTRP2 3.9955 5.4767 3.9339 13.8597
ML-1 [Human leukemia] GDSC1; CTRP2 4.2239 7.3267 3.6042 14.4165
ASH-3 GDSC1 5.4661 6.8231 2.918 0.2494
HTC-C3 GDSC1 5.4859 7.3318 2.7412 0.8009
WRO GDSC1 5.7077 7.2185 2.8684 0.2766
K5 GDSC1 5.7223 7.6436 2.7213 0.7068
FTC-133 GDSC1; CTRP2 6.0642 8.1143 5.0259 4.2431
TT2609-C02 GDSC1; CTRP2 6.7759 13.0847 3.1137 10.8978
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 0.0636 3.0917 0.0281 39.9511
JHU-011 GDSC1 0.4449 5.2861 -0.4973 40.2964
PCI-04B GDSC1 0.5547 6.3717 -0.841 40.5317
SAS GDSC1 1.0634 7.9553 -1.052 38.179
SNU-899 CTRP2 1.3077 5.0276 1.1129 32.198
BICR 16 CTRP2 1.4053 5.131 1.1986 31.5909
BHY GDSC1; CTRP2 1.6198 4.5827 1.522 29.8054
SCC-4 GDSC1; CTRP2 1.7715 5.8884 1.423 29.6411
PCI-06A GDSC1 1.8919 7.6742 -0.1182 30.5728
SCC-25 GDSC1; CTRP2 2.0263 4.1445 1.9969 26.8675
CAL-27 GDSC1; CTRP2 2.1105 4.7213 2.0268 26.4914
Detroit 562 GDSC1; CTRP2 2.2076 4.3242 2.1724 25.6796
SNU-1214 CTRP2 2.3276 4.4821 2.2842 24.9079
HO-1-u-1 GDSC1 2.3974 5.6029 1.3597 19.4541
PE/CA-PJ49 CTRP2 2.4372 4.3192 2.4122 24.1154
PCI-38 GDSC1 2.459 4.726 1.8309 15.7153
BICR 56 CTRP2 2.4797 4.1837 2.4642 23.8006
PE/CA-PJ34 (clone C12) CTRP2 2.5983 3.0404 2.5983 22.9582
PCI-15A GDSC1 2.6296 8.2311 0.2895 25.1653
HSC-3 GDSC1; CTRP2 2.6315 3.9892 2.6266 22.7533
HO-1-N-1 GDSC1 2.6493 5.4017 1.6977 15.8398
BICR 22 GDSC1; CTRP2 2.8799 4.3911 2.8662 21.1282
BB30-HNC GDSC1 2.963 5.8759 1.7553 14.0716
CAL-33 GDSC1; CTRP2 2.989 6.6719 2.5197 22.0187
NCI-H3118 GDSC1 3.1213 19.912 -5.1183 38.179
SCC-9 GDSC1; CTRP2 3.1921 10.395 1.1971 26.1149
OSC-19 GDSC1 3.2404 4.3109 2.7792 4.9878
YD-8 CTRP2 3.2451 7.7805 2.3872 21.7648
SNU-1076 CTRP2 3.2753 5.8159 3.0815 19.1205
SCC-15 GDSC1 3.4059 5.4053 2.3727 7.5763
DOK GDSC1 3.4511 5.8912 2.1669 9.0312
BICR 6 CTRP2 3.4621 5.8466 3.2777 17.8439
SKN-3 GDSC1 3.5174 6.0294 2.1514 8.9218
KOSC-2 GDSC1 3.5471 5.2653 2.5556 5.6545
OSC-20 GDSC1 3.5961 10.7642 -0.1499 23.6558
HSC-2 GDSC1; CTRP2 3.6273 4.0789 3.6273 16.103
SAT [Human HNSCC] GDSC1 3.7604 5.782 2.4614 5.7195
PE/CA-PJ15 GDSC1; CTRP2 3.981 7.6739 3.2059 16.6184
Ca9-22 GDSC1 4.0549 9.5247 0.8331 16.5765
HSC-4 GDSC1; CTRP2 4.0775 6.7586 3.6678 14.5825
LB771-HNC GDSC1 4.1466 7.8217 1.7429 10.0215
BICR 31 GDSC1; CTRP2 4.1568 6.6607 3.7884 13.9016
BICR 78 GDSC1 4.2212 6.772 2.3042 5.6296
FaDu GDSC1; CTRP2 4.3977 7.5757 3.6816 13.6472
SNU-1041 CTRP2 4.4992 9.3688 2.9676 16.2268
BICR 18 CTRP2 4.5892 8.6378 3.3989 14.2814
PCI-30 GDSC1 4.6555 8.118 1.9515 7.1077
SNU-1066 CTRP2 4.9245 8.2274 3.921 11.3506
KON GDSC1 4.9964 6.4699 2.8629 0.6966
PE/CA-PJ41 (clone D2) CTRP2 5.0412 11.5531 2.415 17.1352
BB49-HNC GDSC1 5.5399 7.9052 2.5414 1.6615
BICR 10 GDSC1 5.676 7.4481 2.7747 0.5525
JHU-022 GDSC1 6.2924 13.4348 0.5033 12.4418
SNU-46 CTRP2 7.1193 10.8567 4.4645 4.8298
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 GDSC1; CTRP2 0.3548 5.9014 -0.1263 39.1699
BFTC-905 GDSC1 0.7957 3.765 0.4404 34.0723
RT-112 GDSC1; CTRP2 1.0255 3.0386 1.0179 33.4618
253J CTRP2 1.0732 4.343 0.9714 33.452
JMSU-1 CTRP2 1.2385 3.3506 1.2257 32.0602
U-BLC1 CTRP2 1.5291 6.9942 0.8281 32.3385
VM-CUB-1 CTRP2 1.9757 6.9081 1.3414 29.2541
KU-19-19 GDSC1; CTRP2 2.4727 4.2816 2.4515 23.8662
UM-UC-1 CTRP2 2.5137 7.6263 1.6675 26.4843
647V GDSC1; CTRP2 2.583 6.3737 2.172 24.4965
SCaBER CTRP2 2.6426 5.0319 2.5513 22.9737
UM-UC-3 GDSC1; CTRP2 3.0494 6.987 2.4773 21.9956
RT-4 GDSC1; CTRP2 3.3174 4.5617 3.3083 18.1983
BC-3C CTRP2 3.4302 7.4346 2.72 19.9973
KMBC-2 CTRP2 3.4887 6.0624 3.2503 17.8606
CAL-29 GDSC1; CTRP2 3.5802 6.2262 3.3034 17.3912
HT-1197 GDSC1; CTRP2 3.8717 6.194 3.6308 15.3227
SW780 GDSC1 4.1259 5.9163 2.6466 3.3454
639V GDSC1; CTRP2 4.6271 8.2789 3.6024 13.3704
SW1710 GDSC1; CTRP2 4.6864 6.5307 4.406 10.0591
TCCSUP GDSC1; CTRP2 5.0317 7.7864 4.2324 9.8263
T24 GDSC1; CTRP2 5.2568 10.3483 3.2053 13.513
253J-BV CTRP2 6.0138 17.8912 0.0954 22.8782
J82 GDSC1; CTRP2 6.1627 9.1009 4.6136 5.7897
HT-1376 GDSC1; CTRP2 6.3161 8.9202 4.8262 4.6194
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BPH-1 GDSC1 -5.2145 3.5051 -6.0384 74.4704
PA-1 GDSC1 -3.8235 -1.5635 -3.8254 84.9765
Ca Ski GDSC1 -0.6511 5.9807 -1.935 50.0526
HEY GDSC1 -0.4391 2.1436 -0.5287 47.6062
JAR GDSC1 -0.1913 4.2743 -0.7999 45.7379
NEC8 GDSC1 0.0527 2.4603 -0.0498 41.7618
ME-180 GDSC1 0.876 7.2975 -0.9313 38.8711
HT-3 GDSC1 1.9897 4.3517 1.511 20.3747
SW954 GDSC1 2.0924 4.6449 1.494 19.9693
NCC-IT GDSC1 2.6409 16.6244 -3.8831 37.7514
ACC-OV7 GDSC1 2.8188 5.1938 1.9584 13.1236
MS751 GDSC1 2.9682 3.9805 2.6819 6.9118
OVMIU GDSC1 2.9761 9.2267 0.0985 24.741
NT2-D1 GDSC1 3.029 3.7667 2.8402 5.4327
LB831-BLC GDSC1 3.109 4.0648 2.7794 5.5306
C-33 A GDSC1 3.1359 4.5929 2.5458 7.2355
KGN GDSC1 3.2304 4.4544 2.699 5.657
SW962 GDSC1 3.3106 4.713 2.6394 5.8194
JEG-3 GDSC1 3.335 4.2362 2.8984 3.6879
DSH1 GDSC1 3.3499 5.1177 2.4702 7.0095
OMC-1 [Human cervical carcinoma] GDSC1 3.4033 5.0201 2.5631 6.0851
SiSo GDSC1 3.4396 5.4594 2.3733 7.4528
SKN GDSC1 3.4796 5.923 2.174 8.8761
DoTc2 4510 GDSC1 3.6087 4.8987 2.7839 3.677
HeLa GDSC1; CTRP2 3.6943 4.1059 3.6943 15.6568
JHOS-3 GDSC1 3.9039 5.755 2.5768 4.4223
UWB1.289 GDSC1 4.0083 6.8852 2.1012 7.7488
C-4-I GDSC1 4.0175 5.5657 2.7419 2.9079
CAL-39 GDSC1 4.1014 6.0114 2.5864 3.8424
OVCA433 GDSC1 4.1932 6.9815 2.1847 6.5959
SW756 GDSC1 4.5076 6.1144 2.7772 1.7205
SiHa GDSC1 4.553 5.8224 2.9204 0.8569
HEC-1 GDSC1 5.1865 6.6668 2.8673 0.5389
OVCA420 GDSC1 5.4468 7.3375 2.7226 0.9077
SKG-IIIa GDSC1 5.9118 7.232 2.9354 0.106
PEO1 GDSC1 5.9541 7.8356 2.7422 0.5031
OV17R GDSC1 6.4792 8.6089 2.6652 0.4736
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 A first in man, phase I dose-escalation study of PHA-793887, an inhibitor of multiple cyclin-dependent kinases (CDK2, 1 and 4) reveals unexpected h... Cell Cycle. 2011 Mar 15;10(6):963-70.
2 Liposarcoma: molecular genetics and therapeutics. Sarcoma. 2011;2011:483154.