General Information of Drug (ID: DM36ONA)

Drug Name
Turofexorate isopropyl
Synonyms
629664-81-9; Turofexorate isopropyl; WAY-362450; XL335; isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate; FXR-450; Turofexorate Isopropyl (XL335); UNII-S6KDM312I5; WAY 362450; S6KDM312I5; WAY362450; XL-335; 3-(3,4-difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethyl-Azepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester; 1-methylethyl 3-[(3,4-difluorophenyl)carbonyl]-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate; FXR 450; Turofexorate isopropyl [USAN:I
Indication
Disease Entry ICD 11 Status REF
Hyperlipidaemia 5C80 Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 438.5
Logarithm of the Partition Coefficient (xlogp) 5.1
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C25H24F2N2O3
IUPAC Name
propan-2-yl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Canonical SMILES
CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F
InChI
InChI=1S/C25H24F2N2O3/c1-14(2)32-24(31)17-12-29(23(30)15-9-10-18(26)19(27)11-15)13-25(3,4)21-16-7-5-6-8-20(16)28-22(17)21/h5-12,14,28H,13H2,1-4H3
InChIKey
INASOKQDNHHMRE-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
10026128
CAS Number
629664-81-9
UNII
S6KDM312I5
DrugBank ID
DB12719
TTD ID
D01SYU
VARIDT ID
DR00782

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Farnesoid X-activated receptor (FXR) TTS4UGC NR1H4_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Hyperlipidaemia
ICD Disease Classification 5C80
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Farnesoid X-activated receptor (FXR) DTT NR1H4 5.72E-01 0.39 1.68
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 151 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 8.0445 9.3238 5.6315 0.123
JK1 CTRP2 8.2457 10.8511 5.1333 1.1467
JM1 CTRP2 7.3843 9.2095 5.3897 1.0057
EoL-1 CTRP2 5.1448 9.2182 3.657 11.9117
DoHH2 CTRP2 5.1458 7.304 3.9979 4.507
JVM-2 CTRP2 6.0247 10.3105 3.8949 9.067
EB1 CTRP2 6.6598 11.9199 3.6024 9.1133
KO52 CTRP2 6.8383 8.9363 5.1945 2.2992
MV4-11 CTRP2 6.948 8.5786 5.4276 1.2816
SUP-T1 CTRP2 6.9622 12.3344 3.6277 8.4943
HH [Human lymphoma] CTRP2 7.0275 13.98 2.8631 11.4566
OCI-AML-5 CTRP2 7.0482 9.4957 5.0663 2.5294
Ci-1 CTRP2 7.056 8.0198 5.719 0.2775
MOTN-1 CTRP2 7.0625 8.8445 5.3742 1.355
SET-2 CTRP2 7.063 9.7 4.9798 2.8484
A3/Kawakami CTRP2 7.0677 9.011 5.3022 1.6109
Ki-JK CTRP2 7.1184 8.899 4.4519 0.4311
OPM-2 CTRP2 7.1322 10.7406 4.5294 4.5487
HuT 78 CTRP2 7.1461 9.2966 5.2189 1.8321
Daudi CTRP2 7.1767 11.0835 4.3947 5.0283
HuNS1 CTRP2 7.1931 10 4.9224 2.9053
MC116 CTRP2 7.2185 8.3267 5.6708 0.3126
PF-382 CTRP2 7.2195 9.6104 5.1195 2.1198
SUP-M2 CTRP2 7.2262 11.4668 4.2437 5.5664
SKM-1 CTRP2 7.2392 8.8808 5.4546 0.9161
KHM-1B CTRP2 7.2657 9.7601 5.0788 2.2192
ST486 CTRP2 7.3108 8.9358 5.4678 0.8175
SIG-M5 CTRP2 7.3731 8.3016 5.7425 0.1188
PL21 CTRP2 7.404 8.7918 5.5709 0.4625
DEL CTRP2 7.415 13.5062 3.385 8.7446
MOLT-3 CTRP2 7.4252 8.9677 5.5103 0.6124
Raji CTRP2 7.4525 10.2911 4.9482 2.4947
Reh CTRP2 7.4642 15.8371 2.2751 12.9674
OCI-M1 CTRP2 7.4664 8.576 5.6795 0.1956
TF-1 CTRP2 7.4801 8.6945 5.6411 0.2644
EHEB CTRP2 7.4924 9.6947 4.307 0.5965
NOMO-1 CTRP2 7.5001 12.7041 3.8358 6.8068
MOLT-16 CTRP2 7.5043 9.0057 5.5315 0.5081
SU-DHL-8 CTRP2 7.5291 9.0182 5.5378 0.4786
Karpas-422 CTRP2 7.5334 9.0574 5.5242 0.5108
SUP-B15 CTRP2 7.5534 9.3471 5.4167 0.7953
KMM-1 CTRP2 7.5544 14.5916 2.1657 8.4682
AML-193 CTRP2 7.5673 8.9476 5.5817 0.3552
BL-70 CTRP2 7.5678 8.6408 5.6952 0.1406
Hs 611.T CTRP2 7.5681 9.4722 5.3721 0.918
RPMI-6666 CTRP2 7.5711 9.191 5.4883 0.5833
EJM CTRP2 7.5766 15.3256 2.6106 11.5171
SU-DHL-10 CTRP2 7.594 8.6099 5.7159 0.1061
OCI-Ly3 CTRP2 7.5954 11.852 4.3092 4.7847
SU-DHL-1 CTRP2 7.6006 8.8056 5.6484 0.2079
SU-DHL-4 CTRP2 7.6009 8.851 5.6319 0.2381
CMK CTRP2 7.6041 8.679 5.6953 0.1318
NU-DUL-1 CTRP2 7.6233 10.6004 4.9089 2.45
Peer CTRP2 7.6269 13.7912 3.3975 8.3673
MM1.S CTRP2 7.6291 9.2489 5.4917 0.5413
KE-37 CTRP2 7.6327 8.7806 5.6699 0.1626
GA-10 CTRP2 7.6409 11.2962 4.5998 3.5933
KMS-26 CTRP2 7.6455 8.8797 5.639 0.2104
Kasumi-2 CTRP2 7.6468 14.5201 3.0564 9.6811
HL-60 CTRP2 7.6517 9.0419 5.5813 0.3199
L-363 CTRP2 7.6682 9.085 5.572 0.333
SUP-T11 CTRP2 7.6766 11.2378 4.6491 3.3617
KMS-27 CTRP2 7.7243 9.8069 5.3101 0.9911
MHH-CALL-3 CTRP2 7.7484 10.5141 5.0191 1.9264
Mono-Mac-1 CTRP2 7.7506 11.1805 4.7205 3.0062
L-540 CTRP2 7.753 12.1448 4.2735 4.7166
MOLP-8 CTRP2 7.761 9.5776 5.421 0.6507
Pfeiffer CTRP2 7.7757 9.6399 5.4029 0.6905
JeKo-1 CTRP2 7.7873 9.181 5.5847 0.2625
HD-MY-Z CTRP2 7.7968 9.3361 5.5306 0.3677
RPMI-8226 CTRP2 7.8248 9.8908 5.3244 0.8785
MOLT-13 CTRP2 7.8349 9.7393 5.3904 0.689
WSU-DLCL2 CTRP2 7.8417 8.7765 5.7464 0.0412
P31/FUJ CTRP2 7.8964 9.083 5.6614 0.1147
Granta-519 CTRP2 7.899 15.4425 2.787 10.3328
HT CTRP2 7.9249 9.1364 5.6532 0.1193
P12-Ichikawa CTRP2 7.9322 9.2515 5.6154 0.1689
NCI-H929 CTRP2 7.9398 9.4734 5.5379 0.2979
Jurkat CTRP2 7.9453 9.251 5.6205 0.1584
EM-2 CTRP2 7.9575 9.9154 5.3762 0.6559
MOLM-13 CTRP2 7.9638 9.6589 5.4783 0.4102
697 CTRP2 7.9709 9.5624 5.5175 0.3263
HEL CTRP2 7.9825 9.2881 5.6212 0.1489
Namalwa CTRP2 7.9982 9.6933 5.4796 0.393
SEM CTRP2 8.0111 9.322 5.6199 0.1445
HEL 92.1.7 CTRP2 8.0295 9.0816 5.7087 0.0501
HDLM-2 CTRP2 8.0472 10.5711 5.1519 1.2334
LAMA-84 CTRP2 8.0522 9.7135 5.4942 0.3421
MOLM-6 CTRP2 8.0573 10.4462 5.2086 1.0564
BV-173 CTRP2 8.0809 9.5467 5.5664 0.2051
REC-1 CTRP2 8.0978 10.4173 5.2398 0.9398
KYO-1 CTRP2 8.1111 9.684 5.5285 0.2586
RL CTRP2 8.1129 10.345 5.276 0.8304
OCI-AML-3 CTRP2 8.1264 9.6688 5.54 0.2348
JVM-3 CTRP2 8.1395 9.6549 5.55 0.2152
DB CTRP2 8.1888 9.9992 5.4433 0.3923
KE-97 CTRP2 8.1983 9.91 5.4803 0.317
U266B1 CTRP2 8.2055 9.7021 5.5581 0.1862
SR CTRP2 8.2083 9.797 5.5253 0.2357
MHH-CALL-4 CTRP2 8.2183 9.8814 5.4986 0.2775
MOLM-16 CTRP2 8.2212 10.0659 5.4317 0.4035
SU-DHL-6 CTRP2 8.2217 9.7684 5.5407 0.2081
JURL-MK1 CTRP2 8.2275 9.7461 5.5508 0.1915
Karpas-620 CTRP2 8.2345 9.7495 5.5522 0.1878
Kasumi-1 CTRP2 8.2349 9.861 5.5125 0.2492
KMS-34 CTRP2 8.2563 9.375 5.6882 0.0438
KMS-18 CTRP2 8.2778 16.4565 2.5617 10.6087
RPMI-8402 CTRP2 8.2779 9.6884 5.5896 0.1299
AMO1 CTRP2 8.2934 9.4875 5.6634 0.0573
K-562 CTRP2 8.3016 9.7118 5.5901 0.1251
ME1 CTRP2 8.3406 10.2508 5.4114 0.3987
CA46 CTRP2 8.3531 10.352 5.3785 0.4611
P3HR-1 CTRP2 8.37 9.9566 5.5296 0.1884
MOLP-2 CTRP2 8.3769 10.2664 5.4202 0.3682
A4/Fukuda CTRP2 8.3837 9.7945 5.591 0.1105
ALL-SIL CTRP2 8.3859 10.115 5.4791 0.261
NCO2 CTRP2 8.3961 10.4909 5.3439 0.5173
RCH-ACV CTRP2 8.4042 10.387 5.3865 0.4245
LP-1 CTRP2 8.4743 9.8303 5.6106 0.0794
Toledo CTRP2 8.475 10.1466 5.5016 0.2035
L-428 CTRP2 8.5087 10.0041 5.5636 0.1197
Ri-1 CTRP2 8.5324 11.3045 5.085 1.0952
KMS-20 CTRP2 8.545 9.882 5.6176 0.066
NU-DHL-1 CTRP2 8.5468 10.1284 5.5344 0.146
M-07e CTRP2 8.5545 9.9356 5.6029 0.0765
NALM-6 CTRP2 8.602 11.0145 5.2312 0.6795
GDM-1 CTRP2 8.6067 18.6496 1.7285 13.1079
KCL-22 CTRP2 8.6196 10.0207 5.5968 0.0742
KMS-11 CTRP2 8.6298 10.4343 5.4577 0.23
OCI-Ly10 CTRP2 8.6477 13.1135 4.3713 3.3169
KM-H2 CTRP2 8.7446 10.487 5.4817 0.1726
Ku812 CTRP2 8.7853 10.501 5.4916 0.1532
DND-41 CTRP2 8.8143 10.4078 5.5338 0.1049
KMS-12-BM CTRP2 8.8651 18.4928 1.9853 11.8304
KMS-21-BM CTRP2 8.8752 10.4253 5.549 0.0842
JJN-3 CTRP2 8.8837 10.1953 5.6281 0.034
F-36P CTRP2 8.9809 10.7387 5.4798 0.134
SK-MM-2 CTRP2 9.0302 21.7484 0.5203 16.3679
SUP-HD1 CTRP2 9.101 11.0682 5.4092 0.1931
KMS-28BM CTRP2 9.3727 11.6543 5.3038 0.275
OCI-Ly19 CTRP2 9.8278 22.3077 0.809 14.3281
TALL-1 [Human adult T-ALL] CTRP2 10.344 24.3602 0.1747 15.4932
HPB-ALL CTRP2 10.6168 20.7863 2.0461 9.3149
OCI-AML-2 CTRP2 10.9739 22.5794 1.4351 10.8722
U-937 CTRP2 11.0982 21.5433 1.9921 8.9339
RS4;11 CTRP2 11.2415 24.6764 0.6218 13.0285
THP-1 CTRP2 11.3544 27.7886 -0.7841 16.738
NB4 CTRP2 11.6386 23.8031 1.2811 10.5692
Karpas-299 CTRP2 12.3795 28.3732 -0.3851 14.4477
CML-T1 CTRP2 12.5244 25.6435 0.974 10.5035
Mino CTRP2 12.9373 32.2572 -1.8585 17.3711
⏷ Show the Full List of 151 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 8.5227 10.2847 5.4705 0.2376
TE15 CTRP2 8.6031 10.4191 5.453 0.2436
TE-6 CTRP2 7.1143 8.7823 4.4937 0.3435
TE-5 CTRP2 7.2724 11.4171 4.2998 5.272
KYSE-150 CTRP2 7.5317 9.7468 5.2364 1.3834
OE21 CTRP2 7.7844 9.3459 5.5217 0.3925
KYSE-410 CTRP2 7.8902 10.4362 5.1291 1.4286
KYSE-180 CTRP2 7.9592 9.9578 5.3601 0.6967
KYSE-30 CTRP2 8.0117 9.2924 5.6305 0.1306
COLO 680N CTRP2 8.0368 9.2716 5.6468 0.1065
OE19 CTRP2 8.061 9.3051 5.6439 0.1057
KYSE-450 CTRP2 8.0681 11.1682 4.9076 2.0089
EC-GI-10 CTRP2 8.0911 9.9684 5.4141 0.4964
OE33 CTRP2 8.0952 10.2065 5.3231 0.716
TE-10 CTRP2 8.1038 10.5119 5.2041 1.0378
TE-11 CTRP2 8.1121 9.5952 5.561 0.2053
KYSE-510 CTRP2 8.2279 9.5625 5.6151 0.1097
TE-1 CTRP2 8.3525 10.9185 5.1566 1.0098
TE-9 CTRP2 8.3608 9.7547 5.5965 0.1083
TE-4 CTRP2 8.4232 10.3123 5.4218 0.3492
KYSE-520 CTRP2 8.4535 10.5107 5.3604 0.4587
TE-14 CTRP2 8.7618 10.5304 5.4728 0.1803
KYSE-140 CTRP2 8.9396 10.9034 5.4076 0.2289
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.6524 11.5693 5.0342 1.1606
SNU-213 CTRP2 6.7956 14.607 1.6324 11.8015
QGP-1 CTRP2 6.8867 8.4547 4.5232 0.3715
HuP-T3 CTRP2 7.1736 9.8505 4.98 2.7064
YAPC CTRP2 7.5239 8.7798 5.6271 0.2758
KP-2 CTRP2 7.5588 9.5173 5.3486 0.9972
SUIT-2 CTRP2 7.5686 9.9499 5.1679 1.5825
KP-4 CTRP2 7.6913 10.3054 5.0793 1.772
MIA PaCa-2 CTRP2 7.708 9.8305 5.2921 1.0581
PaTu 8988t CTRP2 7.7377 8.7102 5.7328 0.0636
SU.86.86 CTRP2 7.7905 9.5682 5.4382 0.5893
PaTu 8902 CTRP2 7.8114 8.956 5.6747 0.1148
Panc 02.03 CTRP2 7.8344 9.3225 5.5513 0.666
Capan-1 CTRP2 7.8858 9.8768 5.3588 0.7434
HPAC CTRP2 7.9649 9.902 5.3847 0.6301
Panc 03.27 CTRP2 7.9984 9.8795 5.4084 0.5542
L3.3 CTRP2 8.0591 9.5071 5.5723 0.2018
SNU-410 CTRP2 8.0741 11.3211 4.8439 2.2222
HuP-T4 CTRP2 8.1611 10.0856 5.3991 0.4986
TCC-Pan2 CTRP2 8.2327 9.4996 5.6383 0.0854
Hs 766T CTRP2 8.2503 10.2108 5.389 0.4816
DAN-G CTRP2 8.2873 9.4769 5.6648 0.0568
CFPAC-1 CTRP2 8.3402 9.7898 5.577 0.1334
PK-45H CTRP2 8.3637 14.0884 3.752 5.9486
HPAF-II CTRP2 8.3899 10.8037 5.2198 0.8179
PK-59 CTRP2 8.433 16.6699 2.5665 10.3613
Capan-2 CTRP2 8.4909 10.0551 5.5396 0.1502
PSN1 CTRP2 8.6091 10.5143 5.4211 0.2925
SW1990 CTRP2 8.6284 10.4163 5.4636 0.2218
PaTu 8988s CTRP2 8.6539 16.3107 2.8893 8.8427
AsPC-1 CTRP2 8.6596 12.416 4.6836 2.2327
Panc 10.05 CTRP2 8.6929 10.2524 5.544 0.1119
Panc 04.03 CTRP2 8.9116 10.6105 5.499 0.1248
KP-3 CTRP2 9.0565 11.237 5.3329 0.3104
Panc 08.13 CTRP2 9.1453 10.9324 5.4717 0.1184
BxPC-3 CTRP2 9.2461 24.666 -0.7516 19.5828
Panc 05.04 CTRP2 12.5464 26.5755 0.5586 11.6777
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 12.2423 27.2712 0.0446 13.4586
SK-MEL-24 CTRP2 6.0672 7.3646 5.4033 2.6511
SK-MEL-28 CTRP2 7.0837 7.9113 5.7716 0.1541
SK-MEL-30 CTRP2 7.3022 11.8312 4.1203 5.9531
MDA-MB-435S CTRP2 7.3534 9.1528 5.3979 1.0048
HMCB CTRP2 7.3541 8.5196 5.6547 0.2872
CJM [Human melanoma] CTRP2 7.3926 12.6875 3.7683 7.2393
WM266-4 CTRP2 7.4389 9.5079 5.2903 1.2854
A2058 CTRP2 7.4952 8.9832 5.5364 0.5007
SK-MEL-1 CTRP2 7.5584 8.9262 5.5862 0.3492
SK-MEL-31 CTRP2 7.6113 9.105 5.5401 0.4307
UACC-62 CTRP2 7.6169 12.2381 4.1397 5.4257
SK-MEL-2 CTRP2 7.6559 10.7623 4.8547 2.614
Hs 839.T CTRP2 7.6647 8.6821 5.7165 0.0918
WM115 CTRP2 7.7097 8.9034 5.6553 0.1649
IGR-39 CTRP2 7.7221 9.2808 5.5201 0.4244
Hs 688(A).T CTRP2 7.7362 8.7811 5.7081 0.089
UACC-257 CTRP2 7.7565 11.1519 4.7371 2.9376
WM793 CTRP2 7.7608 9.5166 5.4452 0.5877
K029AX CTRP2 7.7789 10.0626 5.2303 1.1957
Hs 936.T CTRP2 7.8175 8.7505 5.7468 0.0431
G-361 CTRP2 7.821 9.342 5.5385 0.3413
WT2-iPS CTRP2 7.8428 9.1436 5.62 0.1847
A101D CTRP2 7.8439 9.0367 5.6583 0.1291
SK-MEL-3 CTRP2 7.8708 9.7944 5.3848 0.6826
Mel Ho CTRP2 7.8784 9.0513 5.6659 0.1127
IPC-298 CTRP2 7.9048 9.3385 5.5735 0.2442
COLO 829 CTRP2 7.9533 9.9091 5.3768 0.6567
COLO 741 CTRP2 7.9665 9.725 5.4542 0.4623
IGR-37 CTRP2 8 9.2315 5.6474 0.1123
Hs 944.T CTRP2 8.0515 10.7253 5.0893 1.4251
Hs 940.T CTRP2 8.0546 9.7947 5.4648 0.4011
Hs 852.T CTRP2 8.1604 9.6918 5.5447 0.2179
RVH-421 CTRP2 8.1633 9.4914 5.6164 0.1192
SK-MEL-5 CTRP2 8.2207 10.464 5.2778 0.7627
Hs 294T CTRP2 8.2355 9.8216 5.5269 0.2258
HT-144 CTRP2 8.2573 9.5645 5.6249 0.0949
COLO 800 CTRP2 8.265 10.3389 5.3463 0.5713
WM983B CTRP2 8.2667 10.8314 5.1514 1.0801
RPMI-7951 CTRP2 8.2883 9.6079 5.621 0.0943
Mel JuSo CTRP2 8.3095 9.6616 5.6102 0.102
WM88 CTRP2 8.3384 10.2833 5.3983 0.426
LOX-IMVI CTRP2 8.3755 10.8159 5.2085 0.8557
MeWo CTRP2 8.4926 11.0101 5.1845 0.8517
COLO 792 CTRP2 8.4985 10.2824 5.4621 0.257
WM1799 CTRP2 8.9217 17.8817 2.318 10.5671
A-375 CTRP2 9.0594 18.6859 2.0256 11.4102
Hs 895.T CTRP2 10.4786 27.5543 -1.2767 19.1194
IGR-1 CTRP2 10.9319 21.6877 1.8236 9.6747
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-SI9s CTRP2 7.1329 9.1442 5.2802 1.6209
NB1 CTRP2 7.2012 10.2941 4.789 3.4171
NH-6 CTRP2 7.3604 9.0788 5.4328 0.8884
IMR-32 CTRP2 7.5097 8.6971 5.6521 0.2316
SK-N-FI CTRP2 7.6908 9.4657 5.4335 0.6591
CHP-126 CTRP2 7.7013 14.5156 3.0977 9.4351
SK-N-DZ CTRP2 7.7194 9.1536 5.5673 0.3219
MHH-NB-11 CTRP2 7.7519 9.4221 5.4783 0.5093
Kelly CTRP2 7.7765 18.0109 1.4362 15.4319
SK-N-AS CTRP2 7.856 9.2424 5.5894 0.2316
SK-N-BE(2) CTRP2 7.9725 10.3245 5.2175 1.0896
KP-N-YN CTRP2 7.998 10.6802 5.0809 1.495
SK-N-SH CTRP2 8.3524 10.7833 5.2109 0.8627
SiMa CTRP2 8.5451 10.3195 5.4666 0.2378
CHP-212 CTRP2 8.6128 10.2509 5.5158 0.156
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 7.1633 10.999 4.4262 4.9204
SNU-308 CTRP2 7.5533 9.449 5.3744 0.9218
SNU-869 CTRP2 7.635 11.478 4.5112 3.9425
HuCC-T1 CTRP2 8.0208 9.6099 5.52 0.3036
SNU-1196 CTRP2 8.0296 9.7337 5.4774 0.3849
SNU-1079 CTRP2 8.1446 17.0422 2.1824 12.2095
HuH-28 CTRP2 8.2571 9.9326 5.4952 0.2717
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 822.T CTRP2 6.746 7.9506 5.593 0.8963
SK-N-MC CTRP2 7.1698 8.3961 5.6215 0.4648
A-673 CTRP2 7.3301 9.3958 5.2801 1.4212
Hs 888.T CTRP2 7.3689 10.4083 4.8427 2.9939
SW1353 CTRP2 7.4654 20.4341 -0.7378 18.9148
MG-63 CTRP2 7.6336 18.848 0.914 17.3949
SaOS-2 CTRP2 7.6687 10.1727 5.1251 1.636
TC71 CTRP2 7.7573 8.8524 5.6909 0.1052
SK-ES-1 CTRP2 8.025 9.8326 5.4379 0.4725
MHH-ES-1 CTRP2 8.3311 10.3189 5.3819 0.463
HOS CTRP2 8.363 9.5891 5.6532 0.0579
SJSA-1 CTRP2 8.4387 10.6384 5.3057 0.5838
CAL-78 CTRP2 8.4588 9.9338 5.57 0.1209
CADO-ES1 CTRP2 8.5558 9.9798 5.5885 0.0887
G-292 clone A141B1 CTRP2 8.6394 10.6742 5.3748 0.3634
U2OS CTRP2 8.7509 10.6781 5.4166 0.2611
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 71 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MCF-7 CTRP2 6.9549 8.6622 4.4732 0.4553
CAL-148 CTRP2 7.001 9.785 4.8987 3.2522
KPL-1 CTRP2 7.0258 7.7417 5.8106 0.1042
DU4475 CTRP2 7.1445 14.9713 2.4613 12.8103
HCC1419 CTRP2 7.2265 9.4254 5.2078 1.7846
HDQ-P1 CTRP2 7.4866 9.2222 5.4357 0.7858
CAMA-1 CTRP2 7.536 9.0625 4.5533 0.1355
ZR-75-1 CTRP2 7.5902 9.0784 5.5412 0.4385
BT-474 CTRP2 7.5907 8.7731 5.6564 0.197
MDA-MB-453 CTRP2 7.6536 10.6543 4.9023 2.4414
HCC1937 CTRP2 7.7314 11.4025 4.6067 3.4575
Hs 578Bst CTRP2 7.7465 11.8678 4.3995 4.2346
HMC-1-8 CTRP2 7.7654 8.9945 5.6439 0.1681
MDA-MB-468 CTRP2 7.8416 9.8171 5.3622 0.7611
UACC-812 CTRP2 7.8508 9.5287 5.4801 0.4565
HCC38 CTRP2 7.893 11.1238 4.8296 2.4523
HCC1428 CTRP2 7.9935 11.3994 4.7639 2.5843
HCC1395 CTRP2 8.0353 10.2417 5.2815 0.8631
CAL-120 CTRP2 8.0654 9.7485 5.4866 0.3523
MDA-MB-231 CTRP2 8.1064 10.6089 5.1654 1.1495
HCC1954 CTRP2 8.1307 9.907 5.454 0.3931
BT-20 CTRP2 8.1806 12.5214 4.3656 3.8414
SK-BR-3 CTRP2 8.2157 9.8673 5.5027 0.2712
MDA-MB-157 CTRP2 8.2221 10.2522 5.3612 0.557
BT-549 CTRP2 8.2222 10.3236 5.3336 0.6223
HCC202 CTRP2 8.2484 11.329 4.9341 1.762
HCC1569 CTRP2 8.2647 10.8128 5.1581 1.0622
JIMT-1 CTRP2 8.2758 9.5531 5.6352 0.0825
HCC1806 CTRP2 8.3502 10.0864 5.4756 0.2771
HCC1500 CTRP2 8.3799 10.3345 5.3961 0.4143
CAL-51 CTRP2 8.5142 10.1964 5.4987 0.1986
MDA-MB-361 CTRP2 8.6122 11.2844 5.1299 0.926
T-47D CTRP2 8.6195 10.3162 5.4955 0.1801
CAL-85-1 CTRP2 8.6638 11.2763 5.1563 0.83
MDA-MB-415 CTRP2 8.69 10.6331 5.4095 0.2886
HCC1143 CTRP2 8.8595 11.5308 5.1431 0.7625
AU565 CTRP2 9.0509 11.0305 5.404 0.2096
BT164 CTRP2 6.7408 8.6085 5.2859 2.0678
BT 179 CTRP2 7.0848 8.8501 5.3844 1.2957
BT 444 CTRP2 7.2329 8.9776 5.4097 1.0687
BT 482 CTRP2 7.2899 9.7677 5.0899 2.1502
BT 131 CTRP2 7.3629 8.8914 5.5118 0.6487
BT 172 CTRP2 7.3756 12.365 3.913 6.6813
BT 320 CTRP2 7.4049 8.5819 5.6523 0.271
BT 139 CTRP2 7.409 8.5669 5.6597 0.2541
BT 422 CTRP2 7.4326 9.0186 5.4932 0.6559
BT 498 CTRP2 7.5797 9.6159 5.3176 1.0781
BT 271 CTRP2 7.6413 8.8704 5.6408 0.2086
BT 286 CTRP2 7.6426 9.8114 5.267 1.1884
BT 112 CTRP2 7.7275 9.1857 5.5586 0.3369
BT 239 CTRP2 7.7288 8.7634 5.7115 0.0865
BT 228 CTRP2 7.7425 9.7296 5.3509 0.8576
BT 340 CTRP2 7.7537 8.9535 5.6541 0.1557
BT 330 CTRP2 7.7621 8.9012 5.6757 0.1235
BT 232 CTRP2 7.8045 9.06 5.6354 0.171
BT 504 CTRP2 7.8382 9.1289 5.6235 0.1804
BT 416 CTRP2 7.859 9.0801 5.6486 0.1388
BT 440 CTRP2 7.8744 9.1475 5.6306 0.1607
BT 145 CTRP2 7.8961 9.4989 5.5105 0.3694
BT 333 CTRP2 7.9691 9.4434 5.5605 0.2469
BT 159 CTRP2 7.9956 9.2017 5.6561 0.1031
BT 359 CTRP2 8.0712 9.5572 5.5589 0.2196
BT 248 CTRP2 8.0907 13.0634 4.0584 5.1177
BT147 CTRP2 8.1582 10.0113 5.4261 0.4406
BT 224 CTRP2 8.163 9.8997 5.4699 0.3491
BT 187 CTRP2 8.1792 11.1867 4.9589 1.7397
BT 216 CTRP2 8.1946 9.4936 5.6269 0.1023
BT 245 CTRP2 8.2078 9.6147 5.5898 0.143
BT 328 CTRP2 8.2232 9.2205 5.7279 0.0248
BT 428 CTRP2 8.244 9.6012 5.6075 0.1153
BT 231 CTRP2 8.8525 10.5116 5.5119 0.1206
⏷ Show the Full List of 71 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.4175 8.4702 5.6989 0.1767
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-60 CTRP2 6.4112 7.5226 4.6771 0.2343
SNU-1105 CTRP2 6.6648 7.8506 4.6571 0.1867
U-87MG ATCC CTRP2 6.8988 8.1014 4.6559 0.1297
CAS-1 CTRP2 7.0611 8.7497 5.4156 1.2091
KNS-42 CTRP2 7.1468 11.3877 4.2264 5.7553
SNU-466 CTRP2 7.1818 18.2044 0.8844 18.2804
SF295 CTRP2 7.2825 11.1291 4.4452 4.6736
SF268 CTRP2 7.2948 10.6823 4.6664 3.7765
SNU-489 CTRP2 7.323 8.772 5.5415 0.5906
SNU-626 CTRP2 7.3832 8.4985 5.6747 0.2336
LN-18 CTRP2 7.4456 8.5275 5.689 0.1852
NMC-G1 CTRP2 7.49 8.863 5.5811 0.3927
M059K CTRP2 7.5061 9.9326 5.1409 1.7363
SW1783 CTRP2 7.5338 9.8691 5.1843 1.5589
KNS-81 CTRP2 7.5349 8.6307 5.6863 0.1632
CCF-STTG1 CTRP2 7.5593 8.757 5.6499 0.2188
SNU-201 CTRP2 7.5962 10.1699 5.0863 1.8397
Hs 683 CTRP2 7.5982 8.9553 5.5918 0.3198
KG-1-C CTRP2 7.6253 9.0377 5.5719 0.3513
D283 Med CTRP2 7.6774 8.985 5.6131 0.2471
GMS-10 CTRP2 7.7184 9.0379 5.6099 0.2391
A-172 CTRP2 7.7724 11.7555 4.4683 3.9367
DK-MG CTRP2 7.8029 9.6798 5.3994 0.6836
U-251MG CTRP2 7.8538 9.3534 5.5477 0.3101
SNU-738 CTRP2 7.9129 9.2587 5.6055 0.1887
Daoy CTRP2 7.9627 10.3799 5.1896 1.1812
SF539 CTRP2 8.0203 15.4413 2.8734 9.8169
TM-31 CTRP2 8.0352 9.0251 5.7294 0.0359
YKG-1 CTRP2 8.0383 9.6719 5.504 0.3279
GaMG CTRP2 8.0572 9.7077 5.4984 0.332
GB-1 CTRP2 8.1244 10.0639 5.3917 0.5324
42-MG-BA CTRP2 8.1574 9.7028 5.5396 0.2267
SF126 CTRP2 8.1594 9.3626 5.6591 0.0759
8-MG-BA CTRP2 8.1596 9.5402 5.5981 0.142
YH-13 CTRP2 8.2623 10.1875 5.4029 0.4469
U-118MG CTRP2 8.3011 9.9321 5.5123 0.231
DBTRG-05MG CTRP2 8.355 10.7104 5.241 0.7829
Becker CTRP2 8.3568 9.7864 5.5842 0.1223
LN-229 CTRP2 8.437 10.0921 5.5067 0.2052
ONS-76 CTRP2 8.4708 9.8444 5.6046 0.0851
SW1088 CTRP2 8.5085 15.3019 3.273 7.5911
T98G CTRP2 8.5425 17.5051 2.2387 11.4009
KALS-1 CTRP2 8.7069 10.8706 5.3294 0.4252
SNB-75 CTRP2 8.8651 10.6765 5.4596 0.1765
GOS-3 CTRP2 8.9141 10.601 5.5032 0.1203
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-1-B CTRP2 7.2393 8.8516 4.5176 0.2567
KLE CTRP2 7.2596 9.6684 5.117 2.0833
HEC-265 CTRP2 7.5583 8.9887 5.5621 0.4045
EN CTRP2 7.6507 9.0109 5.5926 0.297
RL95-2 CTRP2 7.8045 9.2974 5.5484 0.3273
HEC-108 CTRP2 7.8234 8.9281 5.6886 0.096
AN3-CA CTRP2 7.8714 9.953 5.3213 0.8566
HEC-151 CTRP2 8.0168 9.5188 5.5518 0.2474
ESS-1 CTRP2 8.0647 9.6515 5.5221 0.2847
MFE-319 CTRP2 8.1516 9.8948 5.4671 0.3587
MFE-296 CTRP2 8.1549 10.4281 5.2621 0.8426
JHUEM-7 CTRP2 8.1933 9.7975 5.5193 0.2498
HEC-6 CTRP2 8.3661 10.0383 5.4991 0.2345
HEC-59 CTRP2 8.3706 9.7182 5.6124 0.091
EFE-184 CTRP2 8.3737 9.9056 5.5489 0.1616
JHUEM-3 CTRP2 8.3873 11.1649 5.0728 1.2261
HEC-251 CTRP2 8.4594 9.6705 5.6589 0.0457
JHUEM-2 CTRP2 8.5986 10.5309 5.4111 0.3124
HEC-1-A CTRP2 8.7019 10.6056 5.4239 0.2626
JHUEM-1 CTRP2 8.7284 14.4297 3.8214 5.2385
HEC-50B CTRP2 9.0409 10.8414 5.4659 0.1392
Ishikawa (Heraklio) 02 ER- CTRP2 7.405 8.3938 5.7217 0.1424
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-498 CTRP2 5.9534 6.8798 5.5486 2.2666
SNU-1272 CTRP2 7.5912 9.791 5.249 1.2896
TUHR10TKB CTRP2 7.6262 8.7423 5.6811 0.1471
ACHN CTRP2 7.8418 9.7954 5.3711 0.7367
TUHR4TKB CTRP2 7.8898 9.7585 5.4076 0.6127
KMRC-1 CTRP2 7.9043 9.5428 5.4973 0.3942
CAL-54 CTRP2 7.9349 10.3997 5.1674 1.271
BFTC-909 CTRP2 7.9586 9.2507 5.6255 0.1483
OS-RC-2 CTRP2 7.9766 9.6899 5.4718 0.4186
RCC10RGB CTRP2 8.0301 9.6658 5.503 0.3329
VMRC-RCW CTRP2 8.0334 9.965 5.3904 0.58
TUHR14TKB CTRP2 8.0385 14.0401 3.5614 7.1214
KMRC-20 CTRP2 8.139 9.7632 5.5106 0.2813
786-O CTRP2 8.1698 10.5594 5.2162 0.9598
UO-31 CTRP2 8.4065 10.4419 5.3668 0.464
VMRC-RCZ CTRP2 8.4263 9.9344 5.5581 0.1401
769-P CTRP2 8.9484 10.5051 5.5475 0.0777
Caki-1 CTRP2 11.7884 21.2643 2.5204 6.4982
Caki-2 CTRP2 13.3128 25.0883 1.6803 7.6297
KMRC-2 CTRP2 14.3834 29.6767 0.2418 10.6373
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 CTRP2 -0.87 46.0724 -19.9883 49.3158
DLD-1 CTRP2 7.0419 8.0499 5.701 0.3291
COLO201 CTRP2 7.2435 13.1147 3.4519 8.7483
LS1034 CTRP2 7.3039 9.2766 5.318 1.3149
HT115 CTRP2 7.4574 8.7794 5.5993 0.3657
GP2d CTRP2 7.4815 11.806 4.2554 5.1534
C2BBe1 CTRP2 7.4887 10.6874 4.7877 3.0588
HCC-56 CTRP2 7.5041 8.5595 5.7001 0.1496
SW1417 CTRP2 7.5148 12.5309 3.9298 6.4084
SNU-61 CTRP2 7.5622 10.1153 5.0914 1.8553
MDST8 CTRP2 7.6816 9.1474 5.5539 0.3664
T84 CTRP2 7.739 9.8396 5.3037 0.9996
OUMS-23 CTRP2 7.7671 8.9134 5.6733 0.1256
SNU-C4 CTRP2 7.797 9.2669 5.5568 0.3132
SNU-503 CTRP2 7.8293 13.8843 3.4938 7.6849
RCM-1 [Human ESC] CTRP2 7.8327 9.3873 5.5262 0.3622
HCT 8 CTRP2 7.8685 9.2167 5.6036 0.204
COLO205 CTRP2 7.8913 8.9731 5.6974 0.0761
HT-55 CTRP2 7.8985 9.1555 5.6368 0.1462
CCK-81 CTRP2 7.914 14.9644 3.0302 9.3735
SNU-C1 CTRP2 7.9413 9.6186 5.4841 0.4071
SW948 CTRP2 7.9633 9.5617 5.5146 0.3348
CW-2 CTRP2 7.9673 14.512 3.2863 8.2982
COLO 678 CTRP2 7.973 10.1562 5.2868 0.8879
SNU-407 CTRP2 8.0596 10.5342 5.1734 1.1591
SW620 CTRP2 8.0783 10.219 5.3105 0.7587
LS411N CTRP2 8.0988 9.4353 5.6125 0.136
HT-29 CTRP2 8.1013 9.1637 5.7058 0.0455
HCT 15 CTRP2 8.2217 9.7962 5.5307 0.2235
LS513 CTRP2 8.2351 9.5829 5.6107 0.1133
SK-CO-1 CTRP2 8.3074 9.7665 5.5732 0.1441
RKO CTRP2 8.3095 9.8257 5.5532 0.1694
NCI-H508 CTRP2 8.3625 9.8153 5.5763 0.1303
NCI-H716 CTRP2 8.4388 10.2374 5.4553 0.2851
LS180 CTRP2 8.4558 10.1707 5.4858 0.2315
LS123 CTRP2 8.4638 10.2837 5.4483 0.2895
SW48 CTRP2 8.5539 9.9393 5.6015 0.0778
CL-11 CTRP2 8.5754 10.2564 5.5002 0.1831
KM12 CTRP2 8.5997 10.0933 5.5653 0.1043
HCT 116 CTRP2 8.7251 10.3104 5.5356 0.1156
SNU-C2A CTRP2 8.8662 21.358 0.5929 16.3982
COLO 320 CTRP2 9.1358 11.4333 5.2928 0.3532
SNU-C5 CTRP2 9.5785 20.3986 1.5561 12.2855
SW1116 CTRP2 9.6852 24.5373 -0.3715 17.9344
LoVo CTRP2 11.0883 27.479 -0.8164 17.1646
NCI-H747 CTRP2 11.1701 30.8195 -2.375 20.6753
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 CTRP2 6.9269 8.5764 4.4941 0.4197
SNU-761 CTRP2 7.356 9.0727 4.4828 0.2821
Hep-G2 CTRP2 7.4068 9.084 5.4538 0.7888
JHH-6 CTRP2 7.5439 8.5529 5.7174 0.1146
SK-HEP-1 CTRP2 7.6051 9.1314 5.5271 0.4652
JHH-2 CTRP2 7.6293 11.2945 4.5933 3.6325
JHH-1 CTRP2 7.6821 8.8042 5.6802 0.2901
HuH-1 CTRP2 7.7166 8.9972 5.6241 0.2143
SNU-423 CTRP2 8.1005 9.7682 5.4934 0.326
HLF CTRP2 8.1047 9.9804 5.4153 0.4876
SNU-387 CTRP2 8.1441 14.7943 3.2715 8.1009
JHH-4 CTRP2 8.2511 9.834 5.5284 0.2192
JHH-5 CTRP2 8.2774 12.7348 4.3262 3.878
SNU-878 CTRP2 8.3956 10.3487 5.3973 0.4062
PLC/PRF/5 CTRP2 8.4298 9.9619 5.5498 0.1494
SNU-475 CTRP2 8.4404 9.7046 5.6411 0.0591
SNU-398 CTRP2 8.4561 10.4431 5.3867 0.4046
SNU-449 CTRP2 8.91 14.0418 4.106 3.9933
Li-7 CTRP2 8.9305 10.5899 5.5127 0.109
SNU-182 CTRP2 9.481 24.3912 -0.4465 18.4343
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 141 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1573 CTRP2 6.046 7.8978 5.1191 3.8862
NCI-H1581 CTRP2 6.1514 13.4377 2.4365 14.7296
COR-L88 CTRP2 6.6386 10.149 4.4638 5.5809
LCLC-103H CTRP2 6.6877 7.9513 4.6295 0.2291
NCI-H146 CTRP2 6.7492 34.7536 -7.7272 34.8255
NCI-H2081 CTRP2 6.8281 11.3267 4.0245 7.0865
NCI-H2444 CTRP2 6.9129 7.9714 4.7055 0.0704
NCI-H1573 CTRP2 6.9369 9.1969 5.1354 2.4025
DMS 79 CTRP2 7.1402 9.9518 4.911 3.0176
NCI-H889 CTRP2 7.1777 17.4647 1.249 17.0963
NCI-H1341 CTRP2 7.1783 9.3361 5.2199 1.7926
NCI-H810 CTRP2 7.2065 11.0854 4.4143 4.9058
NCI-H650 CTRP2 7.2226 12.3139 3.0249 5.4382
MOR/CPR CTRP2 7.2444 8.2197 5.7221 0.1918
NCI-H69 CTRP2 7.2503 11.3976 4.2939 5.3281
NCI-H2172 CTRP2 7.3118 9.2867 5.3178 1.3081
BEN CTRP2 7.3545 8.7644 5.5593 0.5217
Sq-1 CTRP2 7.3608 9.8479 5.0954 2.0511
NCI-H2106 CTRP2 7.4146 9.5388 5.2637 1.3978
VMRC-LCD CTRP2 7.421 9.3761 5.3376 1.144
Lu-99 CTRP2 7.4214 9.723 5.1863 1.6601
DV-90 CTRP2 7.4472 14.169 3.0836 9.8902
NCI-H838 CTRP2 7.4549 9.1452 5.452 0.76
NCI-H1838 CTRP2 7.4625 10.8122 4.7133 3.3769
SBC-5 CTRP2 7.519 8.695 5.6566 0.2199
SK-MES-1 CTRP2 7.5204 11.0186 4.6534 3.536
HCC2935 CTRP2 7.5227 9.7102 5.2475 1.3544
NCI-H2342 CTRP2 7.529 9.6012 5.2978 1.1829
LK2 CTRP2 7.5384 8.2972 5.8028 0.0302
NCI-H1184 CTRP2 7.5659 10.1598 5.0737 1.9145
NCI-H1563 CTRP2 7.5678 10.7306 4.8163 2.8568
HCC1195 CTRP2 7.6011 11.5952 4.4344 4.2852
SHP-77 CTRP2 7.6656 9.1123 5.5606 0.3587
COR-L51 CTRP2 7.6853 18.8487 0.953 17.1819
NCI-H1092 CTRP2 7.6949 9.3375 5.4862 0.5195
COLO 668 CTRP2 7.6964 11.3744 4.598 3.5327
NCI-H1793 CTRP2 7.7268 10.3858 5.0636 1.7927
NCI-H2009 CTRP2 7.759 14.7565 3.0215 9.6435
NCI-H520 CTRP2 7.7725 11.0792 4.7797 2.7621
NCI-H23 CTRP2 7.7802 10.9469 4.8441 2.5181
NCI-H2126 CTRP2 7.7876 9.1273 5.6045 0.2264
HCC15 CTRP2 7.7906 13.4069 3.6971 6.9375
HCC366 CTRP2 7.8137 16.0275 2.4396 11.7815
NCI-H446 CTRP2 7.8141 11.7966 4.4753 3.8591
NCI-H460 CTRP2 7.8158 9.0098 5.6574 0.1364
NCI-H2029 CTRP2 7.8271 9.4118 5.5147 0.3894
NCI-H292 CTRP2 7.865 9.7135 5.4143 0.6094
RERF-LC-A1 CTRP2 7.8883 9.7895 5.3947 0.6467
NCI-H226 CTRP2 7.9339 9.2142 5.6292 0.1488
DMS 273 CTRP2 7.9445 9.9895 5.3407 0.7569
T3M-10 CTRP2 7.9451 10.394 5.1749 1.2397
NCI-H1755 CTRP2 7.9659 16.64 2.2501 12.2423
NCI-H1623 CTRP2 7.9672 10.3849 5.1898 1.1774
LUDLU-1 CTRP2 7.9919 12.171 4.4119 3.8868
COR-L95 CTRP2 8.0046 9.4043 5.5883 0.1913
NCI-H2122 CTRP2 8.0057 9.3288 5.6155 0.1515
LXF 289 CTRP2 8.0164 9.8596 5.4239 0.5087
DMS 454 CTRP2 8.0256 14.6635 3.2533 8.3418
KNS-62 CTRP2 8.0281 10.307 5.2516 0.9519
NCI-H1568 CTRP2 8.0378 10.401 5.2178 1.043
ChaGo-K-1 CTRP2 8.038 13.9137 3.6215 6.8873
NCI-H2023 CTRP2 8.0418 9.5636 5.5452 0.2511
NCI-H1155 CTRP2 8.0419 11.6533 4.6779 2.8439
NCI-H2170 CTRP2 8.042 11.403 4.7898 2.4432
IA-LM CTRP2 8.042 9.5765 5.5406 0.259
NCI-H1355 CTRP2 8.0455 10.1799 5.3111 0.7763
HCC827 CTRP2 8.0641 10.9195 5.0131 1.6601
LC-1/sq-SF CTRP2 8.0699 9.9138 5.426 0.4792
NCI-H2405 CTRP2 8.0726 15.4954 2.0755 8.0967
NCI-H1373 CTRP2 8.0995 10.2416 5.3111 0.7447
NCI-H358 CTRP2 8.104 13.2674 3.9712 5.4375
NCI-H1339 CTRP2 8.1119 9.4302 5.619 0.1254
HCC1438 CTRP2 8.1123 9.5678 5.5708 0.1903
LOU-NH91 CTRP2 8.1183 9.6106 5.5578 0.2086
NCI-H1975 CTRP2 8.13 10.2126 5.3363 0.6633
NCI-H1395 CTRP2 8.1507 11.3731 4.863 2.0847
NCI-H1666 CTRP2 8.1535 10.3739 5.2831 0.7872
NCI-H1792 CTRP2 8.1659 10.0749 5.4052 0.4828
Calu-1 CTRP2 8.1682 9.9063 5.4695 0.3479
HCC95 CTRP2 8.1751 9.795 5.5132 0.2656
HCC4006 CTRP2 8.2042 9.8381 5.5089 0.2641
NCI-H1869 CTRP2 8.212 10.5076 5.2566 0.8234
DMS 53 CTRP2 8.2163 9.9776 5.4625 0.3442
Calu-3 CTRP2 8.2291 11.533 4.8358 2.1053
NCI-H1694 CTRP2 8.2371 9.7771 5.5434 0.2001
RERF-LC-Ad2 CTRP2 8.2389 15.3389 3.0744 8.7252
NCI-H1105 CTRP2 8.2398 10.0928 5.4292 0.4013
NCI-H2030 CTRP2 8.2529 9.7273 5.5669 0.1633
HCC78 CTRP2 8.2561 9.8189 5.5357 0.2068
NCI-H522 CTRP2 8.2591 10.1181 5.4276 0.397
Calu-6 CTRP2 8.288 9.9761 5.4914 0.2688
DMS 114 CTRP2 8.3238 9.8228 5.5595 0.1581
RERF-LC-MS CTRP2 8.3351 9.7424 5.5916 0.1177
EPLC-272H CTRP2 8.3546 10.5798 5.292 0.6563
NCI-H1693 CTRP2 8.367 10.0779 5.4852 0.2563
HCC1588 CTRP2 8.3743 9.8108 5.582 0.1217
NCI-H2110 CTRP2 8.3766 11.1875 5.0583 1.2763
NCI-H196 CTRP2 8.4006 9.6744 5.6376 0.0658
CAL-12T CTRP2 8.427 10.0155 5.53 0.1752
NCI-H322 CTRP2 8.4333 9.9373 5.5596 0.137
NCI-H2291 CTRP2 8.4557 10.3118 5.4349 0.3151
NCI-H1915 CTRP2 8.4594 10.3645 5.4171 0.3459
NCI-H1435 CTRP2 8.4699 10.3602 5.4228 0.332
SK-LU-1 CTRP2 8.492 10.3965 5.4182 0.3331
HCC1171 CTRP2 8.5093 10.8967 5.2364 0.7127
HOP-62 CTRP2 8.5432 10.5418 5.3852 0.3765
PC-14 CTRP2 8.5434 10.1459 5.5271 0.1554
HCC2279 CTRP2 8.5825 20.1224 0.9923 15.5931
NCI-H647 CTRP2 8.5896 10.3937 5.457 0.2411
EBC-1 CTRP2 8.5995 10.1313 5.5523 0.1174
NCI-H2087 CTRP2 8.6089 10.9556 5.2568 0.6171
NCI-H661 CTRP2 8.6133 10.5815 5.3984 0.3298
NCI-H841 CTRP2 8.6701 10.0432 5.6066 0.0619
NCI-H1299 CTRP2 8.6988 10.7357 5.3758 0.3428
COLO 699 CTRP2 8.7229 19.9544 1.1756 14.7849
LCLC-97TM1 CTRP2 8.7775 10.6245 5.4456 0.2127
HCC2108 CTRP2 8.7797 18.3202 2.0095 11.8697
NCI-H2228 CTRP2 8.8009 16.6128 2.8432 8.8132
EKVX CTRP2 8.8143 11.1701 5.2615 0.52
NCI-H2196 CTRP2 8.8171 10.2476 5.5885 0.0609
NCI-H1651 CTRP2 8.8322 10.8068 5.4015 0.2633
COR-L105 CTRP2 8.928 10.9405 5.3901 0.2565
HOP-92 CTRP2 8.9555 10.8099 5.4461 0.1759
NCI-H211 CTRP2 8.9802 16.1406 3.1829 7.3133
SW1271 CTRP2 8.9816 10.4351 5.582 0.0517
NCI-H727 CTRP2 8.9864 10.663 5.5075 0.1064
NCI-H1944 CTRP2 9.0045 10.6804 5.5079 0.1038
HCC1833 CTRP2 9.3267 19.3148 1.9051 11.4537
A-549 CTRP2 9.4677 19.4615 1.9296 11.1752
NCI-H1734 CTRP2 9.9724 25.6697 -0.7186 18.436
HARA [Human squamous cell lung carcinoma] CTRP2 10.2543 19.9144 2.2251 9.1473
NCI-H1650 CTRP2 10.3454 19.2847 2.5726 7.8487
RERF-LC-Ad1 CTRP2 10.3902 23.3906 0.6711 13.9786
NCI-H1703 CTRP2 10.5814 20.3183 2.2407 8.7047
NCI-H2085 CTRP2 10.8942 26.9818 -0.7101 17.1487
NCI-H526 CTRP2 11.1435 28.8508 -1.4398 18.6179
Lu-65 CTRP2 11.1896 24.1065 0.8569 12.3939
HCC44 CTRP2 11.362 27.2573 -0.5246 16.0599
NCI-H441 CTRP2 12.2116 24.4175 1.3467 9.7313
NCI-H2286 CTRP2 13.7 31.5146 -1.0164 14.5452
Hs 888.Lu CTRP2 7.8957 10.3147 5.1833 1.2516
⏷ Show the Full List of 141 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 7.0945 7.9811 5.75 0.1922
SYO-1 CTRP2 8.424 9.9759 5.5428 0.1592
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 7.5982 9.1573 5.5139 0.5016
Yamato-SS CTRP2 7.7496 9.2038 5.561 0.3231
TE 441.T CTRP2 7.1267 9.9006 4.9264 2.9748
BT-12 CTRP2 7.2657 8.2497 5.7195 0.1891
TE 617.T CTRP2 7.389 10.7342 4.703 3.5099
Rh41 CTRP2 7.3892 9.557 5.2418 1.4975
Tm87-16 CTRP2 7.4295 24.5935 -2.1026 25.6447
RKN CTRP2 7.701 9.2085 5.5388 0.3914
MES-SA CTRP2 7.7283 8.8201 5.6916 0.1099
HT-1080 CTRP2 7.8083 9.1565 5.602 0.2245
SW982 CTRP2 7.8228 8.9266 5.689 0.0957
BT-16 CTRP2 7.8759 9.18 5.6196 0.1767
KYM-1 CTRP2 7.9108 9.3301 5.579 0.2328
GCT CTRP2 8.1427 9.6376 5.5574 0.2028
A-204 CTRP2 8.2716 12.2896 4.5246 3.1564
Hs 729.T CTRP2 8.3568 11.4963 4.919 1.7213
TTC-709 CTRP2 8.4259 9.9792 5.5423 0.1594
Rh18 CTRP2 8.4678 9.9189 5.5782 0.1108
SK-LMS-1 CTRP2 8.529 11.1447 5.1476 0.9275
G-401 CTRP2 8.5637 11.1308 5.1689 0.8524
G-402 CTRP2 8.7459 11.6041 5.0637 1.0232
RD CTRP2 11.8839 23.392 1.6188 9.2512
SK-UT-1 CTRP2 13.6807 27.193 0.952 9.3792
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.8168 9.3817 5.5217 0.3785
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 8.4331 10.49 5.3597 0.4681
A2780 CTRP2 7.0425 11.1458 4.2701 5.7358
OVSAHO CTRP2 7.112 16.1974 1.0831 13.393
ES2 CTRP2 7.2969 9.3694 5.2732 1.4774
OVCAR-5 CTRP2 7.3851 11.4349 4.368 4.8385
JHOM-1 CTRP2 7.3949 9.4981 5.2707 1.392
OV56 CTRP2 7.4235 8.5262 5.6807 0.2076
OVISE CTRP2 7.6816 8.9963 5.6106 0.2503
OAW42 CTRP2 7.7351 8.6858 5.7402 0.0573
SK-OV-3 CTRP2 7.7788 15.8361 2.508 11.5803
JHOC-5 CTRP2 7.7922 13.5133 3.6471 7.1331
OVK18 CTRP2 7.842 11.1426 4.7918 2.6423
Caov-3 CTRP2 7.8547 16.6923 2.1434 12.8104
OVCAR-4 CTRP2 7.9617 12.9589 4.0247 5.4149
SNU-8 CTRP2 7.9742 9.3506 5.596 0.1874
COV362 CTRP2 8.0458 10.4002 5.2219 1.0254
OC 314 CTRP2 8.0706 10.4272 5.2228 1.0062
JHOS-2 CTRP2 8.0819 9.3889 5.6225 0.1269
EFO-27 CTRP2 8.1007 10.7412 5.1075 1.3297
FU-OV-1 CTRP2 8.1081 9.658 5.5368 0.2455
TYK-nu CTRP2 8.1085 10.5184 5.2037 1.0358
COV434 CTRP2 8.1387 10.6451 5.1662 1.1244
OV-90 CTRP2 8.1414 10.2448 5.3288 0.6762
DOV13 CTRP2 8.1707 9.8169 5.5034 0.284
OV7 CTRP2 8.1767 10.0421 5.4222 0.4413
MCAS CTRP2 8.2396 9.691 5.5748 0.1558
HEY A8 CTRP2 8.3032 10.033 5.4767 0.2895
EFO-21 CTRP2 8.3795 9.7517 5.6041 0.0978
ONCO-DG-1 CTRP2 8.5191 9.9965 5.5699 0.1116
Kuramochi CTRP2 8.5911 10.279 5.4981 0.1826
SNU-119 CTRP2 8.5919 10.2131 5.5214 0.1532
IGROV-1 CTRP2 8.6236 10.3558 5.4831 0.1956
OVCAR-8 CTRP2 8.7016 10.5371 5.4482 0.2265
TOV-112D CTRP2 8.9909 10.581 5.5366 0.0815
OVTOKO CTRP2 9.1547 10.7762 5.5274 0.0721
OAW28 CTRP2 9.3511 11.4704 5.3603 0.2052
RMG-I CTRP2 10.1122 21.6398 1.3206 12.3313
COV644 CTRP2 11.5551 21.1622 2.4339 7.0063
SNU-840 CTRP2 14.4131 30.0791 0.0774 11.0412
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 7.1671 9.8435 4.9791 2.7179
ACC-MESO-1 CTRP2 7.3073 9.0676 5.4103 1.0029
MPP 89 CTRP2 7.8828 9.6287 5.4553 0.4992
IST-Mes1 CTRP2 8.1377 10.2033 5.3434 0.6416
JL-1 CTRP2 8.4531 11.3777 5.0171 1.3445
NCI-H28 CTRP2 8.5307 10.2935 5.4704 0.2358
NCI-H2452 CTRP2 8.8534 10.8009 5.4116 0.2431
NCI-H2052 CTRP2 12.4792 24.5783 1.4321 9.1895
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP CTRP2 7.3929 9.506 5.2662 1.4093
PaCa-3 CTRP2 7.9365 9.0076 5.7015 0.0663
22Rv1 CTRP2 8.3637 11.3966 4.9647 1.5712
LNCaP clone FGC CTRP2 8.4008 10.3879 5.3847 0.4294
DU145 CTRP2 8.514 10.3704 5.4364 0.2948
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 6.9838 8.3618 5.5432 0.8432
A-253 CTRP2 8.3606 10.0549 5.491 0.2487
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 6.9164 9.7937 4.8373 3.6174
GSU CTRP2 6.9974 7.9238 5.7307 0.2788
MKN45 CTRP2 7.1884 8.3759 5.6382 0.4093
ECC10 CTRP2 7.3564 11.3311 4.3984 4.7572
ECC12 CTRP2 7.4236 8.7704 5.588 0.4092
SH-10-TC CTRP2 7.7046 9.7083 5.3413 0.9119
SNU-668 CTRP2 7.782 10.3567 5.1062 1.5968
SNU-1 CTRP2 7.8833 11.3622 4.7167 2.8726
23132/87 CTRP2 7.8884 9.3136 5.5762 0.2447
OCUM-1 CTRP2 7.9782 10.0253 5.3419 1.5752
SNU-620 CTRP2 8.0074 9.1746 5.6696 0.0868
NUGC-4 CTRP2 8.0384 9.6917 5.4967 0.3422
NCI-N87 CTRP2 8.0414 10.4761 5.1885 1.127
SNU-5 CTRP2 8.0783 10.1868 5.3233 0.725
Hs 746.T CTRP2 8.105 10.2729 5.3012 0.7677
HuG1-N CTRP2 8.1359 9.6818 5.5389 0.2339
LMSU CTRP2 8.1553 9.727 5.5302 0.2428
MKN1 CTRP2 8.1836 9.5438 5.6056 0.1282
NUGC-3 CTRP2 8.2274 10.4914 5.27 0.7792
MKN7 CTRP2 8.2436 15.1452 3.1707 8.3488
SNU-216 CTRP2 8.2644 9.7484 5.5638 0.165
Fu97 CTRP2 8.2787 9.8516 5.5326 0.2058
AGS CTRP2 8.4611 9.6135 5.6782 0.0347
KATO III CTRP2 8.4672 10.1498 5.4976 0.2112
SNU-719 CTRP2 8.5007 10.2229 5.4842 0.2226
SNU-601 CTRP2 8.5511 15.6459 3.1377 8.0476
IM95 CTRP2 8.6508 17.7695 2.1862 11.4302
MKN74 CTRP2 8.7632 10.9044 5.3394 0.387
KE-39 CTRP2 9.2925 14.1691 4.263 3.0742
HGC-27 CTRP2 10.8663 18.5321 3.2135 5.1274
GSS CTRP2 11.4913 27.5779 -0.5911 16.0687
SNU-685 CTRP2 7.6472 9.0194 5.588 0.3079
SNG-M CTRP2 8.2528 9.5938 5.6132 0.1076
SNU-1077 CTRP2 8.4043 10.1315 5.4802 0.2539
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-62 CTRP2 6.8304 10.0556 4.6501 4.5064
CGTH-W-1 CTRP2 7.673 9.2252 5.5204 0.4474
FTC-133 CTRP2 7.8677 9.2197 5.6022 0.2065
SW579 CTRP2 7.91 11.0621 4.8668 2.3025
BHT-101 CTRP2 7.954 9.4343 5.5579 0.2563
B-CPAP CTRP2 7.9715 9.5672 5.5159 0.3291
TT CTRP2 8.0521 9.596 5.5375 0.2614
8305C CTRP2 8.1282 9.5817 5.5718 0.1849
ML-1 [Human leukemia] CTRP2 8.1948 10.1254 5.3982 0.4857
FTC-238 CTRP2 8.4221 9.9678 5.5449 0.1569
8505C CTRP2 8.579 11.2371 5.1336 0.9354
TT2609-C02 CTRP2 8.7329 10.5447 5.4572 0.2068
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Detroit 562 CTRP2 7.1598 8.4915 4.6151 0.1299
SNU-46 CTRP2 7.1932 20.9955 -0.4967 22.2766
HSC-3 CTRP2 7.2099 8.5241 4.6218 0.1128
PE/CA-PJ49 CTRP2 7.2492 8.7438 5.5174 0.712
YD-10B CTRP2 7.5032 9.1199 5.4854 0.6325
SNU-1076 CTRP2 7.5712 8.8414 5.6235 0.2652
CAL-27 CTRP2 7.6568 9.501 5.4033 0.7642
BICR 56 CTRP2 7.6727 9.2054 5.5279 0.4298
HSC-4 CTRP2 7.6925 11.2478 4.6543 3.323
HSC-2 CTRP2 7.7058 10.0403 5.2022 1.3456
BHY CTRP2 7.7206 9.845 5.2924 1.0478
BICR 22 CTRP2 7.7635 8.806 5.7092 0.0833
PE/CA-PJ41 (clone D2) CTRP2 7.7663 9.2764 5.5405 0.3594
SNU-1214 CTRP2 7.7891 10.6798 4.9685 2.0638
BICR 16 CTRP2 7.8072 9.3904 5.5144 0.3987
BICR 6 CTRP2 7.8124 9.5826 5.4423 0.5669
SCC-25 CTRP2 7.8677 9.53 5.4868 0.4335
FaDu CTRP2 7.9056 9.9489 5.339 0.7853
PE/CA-PJ15 CTRP2 7.9638 10.4221 5.1726 1.2327
CAL-33 CTRP2 8.163 9.593 5.5808 0.1641
BICR 31 CTRP2 8.1676 9.9022 5.4708 0.3456
SNU-899 CTRP2 8.3303 9.6467 5.6225 0.087
SCC-9 CTRP2 8.4864 9.8177 5.6191 0.0711
SCC-4 CTRP2 8.4971 9.9915 5.5638 0.1214
BICR 18 CTRP2 8.5262 10.2075 5.4992 0.1952
PE/CA-PJ34 (clone C12) CTRP2 8.6702 10.0587 5.6014 0.0655
SNU-1066 CTRP2 8.9442 10.5006 5.5475 0.078
YD-8 CTRP2 12.5305 26.1296 0.7545 11.1348
SNU-1041 CTRP2 13.4701 27.8898 -0.3557 9.9424
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2 1.0194 10.2907 -5.8022 18.7951
CAL-29 CTRP2 7.3635 10.2769 4.9004 2.7794
639V CTRP2 7.4125 8.3192 5.7509 0.0981
647V CTRP2 7.4525 11.2867 4.4834 4.2886
KU-19-19 CTRP2 7.4685 8.647 5.6541 0.2427
253J-BV CTRP2 7.5354 8.9415 5.5704 0.3958
UM-UC-1 CTRP2 7.6821 14.1451 3.2645 8.8093
BC-3C CTRP2 7.6867 9.9467 5.2322 1.2639
JMSU-1 CTRP2 7.7132 9.2979 5.5096 0.4531
253J CTRP2 7.7513 9.7769 5.3357 0.8956
U-BLC1 CTRP2 7.7615 9.7298 5.3599 0.8189
RT-4 CTRP2 7.8332 9.7111 5.4009 0.6621
BFTC-905 CTRP2 7.8683 9.2388 5.5955 0.2174
RT-112 CTRP2 8.1047 9.6339 5.5442 0.2341
J82 CTRP2 8.2122 11.5584 4.8156 2.1896
TCCSUP CTRP2 8.48 10.3835 5.4183 0.3369
SCaBER CTRP2 8.5865 15.1126 3.4135 6.9533
UM-UC-3 CTRP2 8.6097 18.8177 1.6489 13.3772
VM-CUB-1 CTRP2 8.6279 18.7201 1.7092 13.1423
T24 CTRP2 8.6604 10.5337 5.4338 0.2582
HT-1376 CTRP2 8.7906 10.4638 5.5063 0.1359
SW1710 CTRP2 8.9794 10.8505 5.4407 0.1779
KMBC-2 CTRP2 9.1975 11.0342 5.4554 0.1267
5637 CTRP2 13.9313 33.5257 -1.8109 16.146
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.7296 8.6155 5.7618 0.0408

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025892)
2 A synthetic farnesoid X receptor (FXR) agonist promotes cholesterol lowering in models of dyslipidemia. Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G543-52.