Details of the Drug

General Information of Drug (ID: DM3827C)

Drug Name
AZD4547
Synonyms
AZD4547; 1035270-39-3; AZD-4547; AZD 4547; UNII-2167OG1EKJ; 2167OG1EKJ; CHEBI:63453; KB-74810; N-(5-(3,5-Dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3R,5S)-rel-3,5-dimethylpiperazin-1-yl)benzamide; N-{5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl}-4-(cis-3,5-dimethylpiperazin-1-yl)benzamide; rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide; N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2/3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 463.6
Logarithm of the Partition Coefficient (xlogp) 3.9
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C26H33N5O3
IUPAC Name
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3S,5R)-3,5-dimethylpiperazin-1-yl]benzamide
Canonical SMILES
C[C@@H]1CN(C[C@@H](N1)C)C2=CC=C(C=C2)C(=O)NC3=NNC(=C3)CCC4=CC(=CC(=C4)OC)OC
InChI
InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21(29-30-25)8-5-19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,(H2,28,29,30,32)/t17-,18+
InChIKey
VRQMAABPASPXMW-HDICACEKSA-N
Cross-matching ID
PubChem CID
51039095
ChEBI ID
CHEBI:63453
CAS Number
1035270-39-3
UNII
2167OG1EKJ
DrugBank ID
DB12247
TTD ID
D0NU0U
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fibroblast growth factor receptor (FGFR) TT0LF7H NOUNIPROTAC Inhibitor [2]
Fibroblast growth factor receptor 1 (FGFR1) TTRLW2X FGFR1_HUMAN Modulator [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Fibroblast growth factor receptor substrate 2 (FRS2) OTDMD800 FRS2_HUMAN Post-Translational Modifications [4]
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) OTUYHB84 MLP3B_HUMAN Gene/Protein Processing [4]
Proline-rich AKT1 substrate 1 (AKT1S1) OT4JHN4Y AKTS1_HUMAN Post-Translational Modifications [4]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [4]
Small ribosomal subunit protein eS6 (RPS6) OTT4D1LN RS6_HUMAN Post-Translational Modifications [4]
Sterol regulatory element-binding protein 1 (SREBF1) OTWBRPAI SRBP1_HUMAN Gene/Protein Processing [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fibroblast growth factor receptor 1 (FGFR1) DTT FGFR1 4.79E-02 -0.03 -0.15
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 3.5039 4.8473 2.7051 2.5556
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 -1.8308 3.0222 -1.9523 49.233
H-EMC-SS GDSC1; GDSC2 -1.2634 6.2619 -2.7072 38.5561
CAL-78 GDSC1; GDSC2; CTRP2 -0.6206 4.1697 -0.8166 42.0713
CHSA0011 GDSC1; GDSC2 -0.1026 5.4142 -1.1395 34.3609
CAL-72 GDSC1; GDSC2 0.5878 6.8238 -1.0218 26.9697
HuO9 GDSC1; GDSC2 1.3539 4.1758 0.8927 16.7008
NY GDSC1; GDSC2 1.3937 7.3089 -0.4414 22.2766
NOS-1 [Human HNSCC] GDSC1; GDSC2 1.4831 3.3801 1.299 14.569
SK-ES-1 GDSC1; GDSC2; CTRP2 1.5608 4.6574 1.4484 28.3615
SK-PN-DW GDSC1; GDSC2 1.711 4.7515 -1.1468 3.5373
EW-3 GDSC1; GDSC2 1.7422 4.2804 1.2666 13.8618
ES5 GDSC1; GDSC2 1.7976 4.2924 1.3204 15.7891
EW-18 GDSC1; GDSC2 1.8674 3.7293 1.6073 12.0007
EW-11 GDSC1; GDSC2 1.9195 5.7519 0.8045 15.3957
ES8 GDSC1; GDSC2 1.9292 4.6279 1.319 13.06
HuO-3N1 GDSC1; GDSC2 1.9543 5.7933 0.8198 15.2291
SK-N-MC CTRP2 2.0277 3.1232 2.0274 26.7605
CHSA8926 GDSC1; GDSC2 2.044 4.6932 1.4092 12.3169
ES1 GDSC1; GDSC2 2.1075 3.9762 1.7743 10.5158
EW-16 GDSC1; GDSC2 2.2967 4.382 1.8049 9.8036
EW-12 GDSC2 2.312 3.7621 2.0745 11.433
Hs 822.T CTRP2 2.3918 7.1512 1.7093 26.7098
Hs 888.T CTRP2 2.4623 4.5329 2.4211 24.0033
EW-7 GDSC1; GDSC2 2.565 4.2105 2.1555 7.4459
MHH-ES-1 GDSC1; GDSC2; CTRP2 2.6079 5.4728 2.4332 22.0287
EW-1 GDSC1; GDSC2 2.6217 4.8014 1.9404 8.2659
U2OS GDSC1; GDSC2; CTRP2 2.6795 6.455 2.2523 22.4283
ES7 GDSC1; GDSC2 2.7457 4.3778 2.2609 6.4536
ES6 GDSC1; GDSC2 2.8075 6.3504 1.3601 10.4971
CHSA0108 GDSC1; GDSC2 2.9184 10.2762 -0.4969 21.223
SaOS-2 GDSC1; GDSC2; CTRP2 2.9292 4.565 2.9069 19.5288
TC-71 GDSC1; GDSC2 3.1003 4.5528 2.5133 4.352
HOS GDSC1; GDSC2; CTRP2 3.1493 5.106 3.0828 18.2954
ES4 GDSC1; GDSC2 3.1592 8.5423 0.5749 13.3168
EW-22 GDSC1; GDSC2 3.2216 4.5987 2.5981 3.6624
A-673 GDSC1; GDSC2 3.2878 6.1579 1.8754 6.9431
SW1353 CTRP2 3.3851 7.6734 2.5783 20.6568
EW-13 GDSC1; GDSC2 3.4781 6.4033 1.9094 6.374
SJSA-1 GDSC1; GDSC2; CTRP2 3.7255 5.8877 3.5547 15.041
MG-63 GDSC1; GDSC2; CTRP2 3.7984 11.5066 1.2726 22.8787
U-CH2 GDSC2 4.0346 6.043 2.4997 3.4621
EW-24 GDSC1; GDSC2 4.2101 5.6261 2.7987 1.0903
CADO-ES1 GDSC1; GDSC2 5.5681 7.1163 2.8191 0.2144
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.2456 5.1046 2.1122 25.7622
TE15 CTRP2 2.9889 6.9948 2.4093 22.4222
TE-15 GDSC1 2.706 5.1953 1.8329 10.0205
TE-8 GDSC1; GDSC2 2.7901 12.1498 -1.5427 22.7196
T.T GDSC1; GDSC2 2.7987 4.4338 2.2866 6.1899
TE-11 GDSC1; GDSC2 3.0462 7.2365 1.1304 12.8856
EC-GI-10 GDSC1; GDSC2 3.5297 5.0438 2.6274 2.8716
OE21 GDSC1; GDSC2 3.5978 5.569 2.4192 3.7212
KYSE-270 GDSC1; GDSC2 3.6168 5.8076 2.3155 4.1735
OE33 GDSC1; GDSC2 3.8242 5.6407 2.5497 2.7056
TE-1 GDSC1; GDSC2; CTRP2 3.9442 7.7504 3.1355 15.9329
TE-6 GDSC1; GDSC2; CTRP2 4.0846 6.8693 2.1366 4.1669
TE-4 GDSC1; GDSC2; CTRP2 4.1642 6.0029 4.0037 12.2695
KYSE-510 GDSC1; GDSC2; CTRP2 4.2891 9.0773 2.8975 17.0242
KYSE-410 GDSC1; GDSC2; CTRP2 4.3644 6.6708 4.0085 11.6993
KYSE-30 CTRP2 4.488 5.776 4.4109 10.6342
TE-10 GDSC1; GDSC2; CTRP2 4.513 6.8655 4.0943 11.7325
OE19 GDSC1; GDSC2; CTRP2 4.6484 5.9263 4.5515 9.0352
TE-9 GDSC1; GDSC2; CTRP2 4.7059 6.1164 4.5634 8.8304
TE-5 GDSC1; GDSC2 4.9647 6.8152 2.6803 0.8426
COLO 680N GDSC1; GDSC2; CTRP2 4.9794 7.4285 4.3434 8.9184
TE-14 CTRP2 4.9889 7.7816 4.1922 10.0948
KYSE-180 GDSC1; GDSC2; CTRP2 5.0381 6.1447 4.9172 6.6857
KYSE-140 GDSC1; GDSC2; CTRP2 5.0469 6.5956 4.7678 7.188
KYSE-70 GDSC1; GDSC2; CTRP2 5.1853 8.4515 4.0669 9.5009
KYSE-520 GDSC1; GDSC2; CTRP2 5.4411 9.5739 3.7547 10.1748
KYSE-450 GDSC1; GDSC2; CTRP2 5.5004 5.9923 5.4641 3.5162
KYSE-150 GDSC1; GDSC2; CTRP2 5.9615 15.7411 1.1268 18.7652
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.7863 7.9424 3.9159 11.7128
QGP-1 GDSC1; GDSC2; CTRP2 2.5029 6.6842 1.9876 25.3958
PSN1 GDSC1; GDSC2; CTRP2 3.4895 5.8043 3.3178 16.5168
PaTu 8988s CTRP2 3.6334 6.1196 3.3923 16.9082
AsPC-1 GDSC1; GDSC2; CTRP2 3.7601 6.1031 3.5352 15.0078
BxPC-3 GDSC1; GDSC2; CTRP2 3.8012 6.4585 3.4719 15.1096
MZ-PC-1 GDSC1; GDSC2 3.8632 6.5837 2.1172 5.4484
Panc 08.13 GDSC1; GDSC2; CTRP2 3.9722 6.7759 3.5481 14.3777
KP-1N GDSC1; GDSC2 4.0256 6.4256 2.3102 3.4692
HPAC GDSC1; GDSC2; CTRP2 4.0731 5.5215 4.0099 12.5155
YAPC GDSC1; GDSC2; CTRP2 4.0754 5.6994 3.979 12.61
MIA PaCa-2 GDSC1; GDSC2; CTRP2 4.1428 6.8443 3.7066 13.3606
HuP-T4 GDSC1; GDSC2; CTRP2 4.1434 5.9098 4.0049 12.3256
KP-3 GDSC1; GDSC2; CTRP2 4.1676 6.8139 3.7444 13.1603
SW1990 GDSC1; GDSC2 4.2143 6.1886 2.5464 2.131
TCC-Pan2 CTRP2 4.2529 6.8406 3.826 13.4856
PK-59 CTRP2 4.3096 6.1494 4.1214 12.2195
Panc 10.05 GDSC1; GDSC2; CTRP2 4.3414 6.4689 4.0548 11.5986
Hs 766T GDSC1; GDSC2; CTRP2 4.3706 5.7674 4.2852 10.7307
SNU-213 CTRP2 4.4321 5.3392 4.4158 10.7964
KP-4 GDSC1; GDSC2; CTRP2 4.6277 7.2791 4.0469 10.8794
Panc 05.04 CTRP2 4.6912 7.451 4.0389 11.467
HuP-T3 GDSC1; GDSC2; CTRP2 4.7208 7.3465 4.1146 10.3984
PK-45H CTRP2 4.7647 7.3778 4.1464 10.8499
Capan-2 GDSC1; GDSC2; CTRP2 4.9762 6.7808 4.6191 7.9079
SUIT-2 GDSC1; GDSC2; CTRP2 4.9774 6.8843 4.5777 8.0556
PaTu 8902 GDSC1; GDSC2; CTRP2 5.024 7.3235 4.4357 8.466
CFPAC-1 GDSC1; GDSC2; CTRP2 5.0692 6.6853 4.7558 7.1736
Panc 03.27 GDSC1; GDSC2; CTRP2 5.0846 7.0214 4.6309 7.5926
HPAF-II GDSC1; GDSC2; CTRP2 5.0875 7.3906 4.4698 8.1864
PL4 GDSC1; GDSC2 5.0904 7.1893 2.5876 1.0486
DAN-G GDSC1; GDSC2; CTRP2 5.1013 7.2694 4.5384 7.8961
Capan-1 GDSC1; GDSC2; CTRP2 5.1458 6.7294 4.8185 6.7501
SU.86.86 GDSC1; GDSC2; CTRP2 5.1838 6.184 5.0636 5.7755
PaTu 8988t GDSC1; GDSC2; CTRP2 5.2759 8.5852 4.0879 9.2237
Panc 02.03 GDSC1; GDSC2; CTRP2 5.287 6.092 5.2043 5.0038
KP-2 GDSC1; GDSC2; CTRP2 5.307 6.4601 5.0975 5.3251
L3.3 CTRP2 5.3678 5.8582 5.3472 4.5777
Panc 04.03 GDSC1; GDSC2; CTRP2 5.3787 12.3613 2.3153 15.7889
SNU-410 CTRP2 6.0433 9.7489 4.1913 7.7898
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 73 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 1.4638 8.658 0.15 34.4451
Hs 688(A).T CTRP2 1.6462 6.9305 0.9763 31.4948
G-mel GDSC1; GDSC2 2.4402 4.0077 2.1133 9.3954
IGR-1 GDSC1; GDSC2; CTRP2 2.5921 3.4633 2.592 21.5646
Hs 895.T CTRP2 2.6277 5.9885 2.3308 23.7944
UACC-257 GDSC1; GDSC2; CTRP2 2.7849 3.5885 2.7848 20.3602
G-361 GDSC1; GDSC2; CTRP2 2.8511 3.5058 2.8511 19.9465
LOX-IMVI GDSC1; GDSC2; CTRP2 2.8561 4.9437 2.792 20.1186
Hs 934.T CTRP2 2.9494 8.257 1.8824 24.4474
Hs 938.T GDSC1; GDSC2 3.0073 4.1611 2.6181 4.8093
COLO 800 GDSC1; GDSC2 3.042 5.3397 2.0712 7.7206
VMRC-MELG GDSC1; GDSC2 3.0463 3.7048 2.8706 3.7753
SK-MEL-3 GDSC1; GDSC2 3.0476 4.2202 2.6278 4.6323
MZ-MEL-7 GDSC1; GDSC2 3.0957 4.5311 2.5198 5.0843
IPC-298 GDSC1; GDSC2; CTRP2 3.0964 4.9494 3.0468 19.8075
WM278 GDSC1; GDSC2 3.0982 5.8021 1.8908 7.2995
Hs 940.T GDSC1; GDSC2; CTRP2 3.1891 4.7408 3.1648 19.1042
IST-MEL1 GDSC1; GDSC2 3.2687 5.0546 2.4108 4.4438
Mel JuSo GDSC1; GDSC2; CTRP2 3.3167 5.4675 3.2029 17.4036
CHL-1 GDSC1; GDSC2 3.3448 4.4641 2.7697 2.5728
MeWo GDSC1; GDSC2 3.3503 4.8377 2.5876 3.4257
COLO 792 GDSC1; GDSC2; CTRP2 3.4259 7.5952 2.6524 19.006
Mel Ho GDSC1; GDSC2; CTRP2 3.4495 4.6921 3.4381 17.3256
COLO 783 GDSC1; GDSC2 3.4523 5.0793 2.5494 3.9828
CP50-MEL-B GDSC1; GDSC2 3.6043 5.011 2.6996 2.8088
MZ-MEL-2 GDSC1; GDSC2 3.6963 6.2197 2.172 5.5114
M14 GDSC1; GDSC2 3.7447 6.5046 2.0677 5.0947
RPMI-7951 GDSC1; GDSC2; CTRP2 3.7475 4.8832 3.7355 14.3848
WM1552C GDSC1; GDSC2 3.7833 5.4955 2.5915 2.5822
HMV-II GDSC1; GDSC2 3.8225 5.7282 2.5062 2.9087
A-375 GDSC1; GDSC2; CTRP2 3.8421 6.3452 3.5526 14.7176
SH-4 GDSC1; GDSC2 3.8668 5.6075 2.5952 2.4283
451Lu GDSC1; GDSC2 3.8886 6.225 2.3112 4.337
COLO 679 GDSC1; GDSC2 3.9127 5.3522 2.7468 1.6796
Hs 839.T CTRP2 4.0055 13.4894 0.511 26.1282
GAK GDSC1; GDSC2 4.0278 5.6657 2.673 1.8394
IGR-39 CTRP2 4.038 6.4213 3.7414 14.4223
LB373-MEL-D GDSC1; GDSC2 4.0553 5.4632 2.7831 1.5643
CP66-MEL GDSC1; GDSC2 4.0609 6.0591 2.5094 2.9495
Hs 936.T CTRP2 4.1146 5.3277 4.0821 12.9661
A101D GDSC1; GDSC2; CTRP2 4.1664 5.8498 4.0446 12.1262
A-431 GDSC1; GDSC2 4.1816 6.6054 2.3295 3.6785
MMAc-SF GDSC1; GDSC2 4.2008 6.8148 2.2425 4.1026
SK-MEL-24 GDSC1; GDSC2; CTRP2 4.2863 6.1699 4.09 11.6298
MDA-MB-435S CTRP2 4.295 5.9829 4.1517 12.1544
WM1799 CTRP2 4.3024 6.7066 3.9287 12.956
A2058 GDSC1; GDSC2; CTRP2 4.324 5.3806 4.2979 10.8288
Hs 294T CTRP2 4.3548 6.2131 4.1518 11.9732
WM115 GDSC1; GDSC2; CTRP2 4.3599 5.421 4.3312 10.6128
WM983B CTRP2 4.3962 7.9674 3.5096 14.329
SK-MEL-5 GDSC1; GDSC2; CTRP2 4.4125 5.4259 4.3864 10.9599
HMCB CTRP2 4.4789 12.6487 1.3614 22.2725
SK-MEL-1 GDSC1; GDSC2; CTRP2 4.484 5.8415 4.3923 10.0439
IGR-37 GDSC1; GDSC2; CTRP2 4.5206 4.9948 4.5203 9.5191
Hs 852.T CTRP2 4.6072 6.3814 4.3725 10.413
COLO 829 GDSC1; GDSC2; CTRP2 4.7056 7.3698 4.0889 10.5306
K029AX CTRP2 4.7794 7.4045 4.1499 10.7975
WM35 GDSC1; GDSC2 4.868 6.9312 2.5847 1.2455
A-388 GDSC1; GDSC2 4.9911 7.5832 2.369 2.2658
WM266-4 CTRP2 4.9989 5.7028 4.9752 7.0456
SK-MEL-30 GDSC1; GDSC2; CTRP2 5.0656 5.8818 5.0158 6.6926
HT-144 GDSC1; GDSC2; CTRP2 5.1131 6.998 4.6704 7.3763
RVH-421 GDSC1; GDSC2; CTRP2 5.1632 8.0691 4.2286 9.5227
WM793 GDSC1; GDSC2; CTRP2 5.2142 6.6326 4.9302 6.1694
Hs 944.T CTRP2 5.232 6.8429 4.8602 6.8061
WT2-iPS GDSC1; GDSC2; CTRP2 5.2605 6.4285 5.0601 5.5811
DJM-1 GDSC1; GDSC2 5.31 6.8742 2.807 0.3738
SK-MEL-28 GDSC1; GDSC2; CTRP2 5.44 5.8091 5.4311 4.0566
UACC-62 GDSC1; GDSC2; CTRP2 5.4807 5.9371 5.4549 3.6042
SK-MEL-2 GDSC1; GDSC2; CTRP2 5.4972 6.9162 5.0974 4.8571
LB2518-MEL GDSC1; GDSC2 5.5154 6.5937 2.979 0.0494
SK-MEL-31 GDSC1; GDSC2; CTRP2 5.5652 6.154 5.4878 3.4688
EquiPSC Line K2 GDSC1; GDSC2 4.6393 6.9448 2.4549 2.3234
⏷ Show the Full List of 73 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 205 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 3.9343 5.6394 2.6252 2.5669
KG-1 GDSC1; GDSC2 -2.7828 6.6005 -4.4537 47.3606
OPM-2 GDSC1; GDSC2; CTRP2 -1.1056 1.6297 -1.1136 44.6799
Kasumi-1 GDSC1; GDSC2; CTRP2 -1.0166 2.2243 -1.041 47.0782
MOLM-13 GDSC1; GDSC2; CTRP2 -0.9801 1.3029 -0.9825 43.8838
MV4-11 GDSC1; GDSC2 -0.6506 1.1085 -0.6617 29.9398
EoL-1 GDSC1; GDSC2; CTRP2 0.0147 1.4422 0.0146 37.6638
697 GDSC1; GDSC2; CTRP2 0.2298 1.9679 0.2288 36.3232
KMS-11 GDSC1; GDSC2; CTRP2 0.4555 5.3437 0.1211 38.1767
A4/Fukuda GDSC1; GDSC2 0.5152 3.3725 0.2449 22.191
OCI-Ly7 GDSC1; GDSC2 0.6524 1.5486 0.6512 26.7947
KMS-12-BM GDSC1; GDSC2; CTRP2 0.8663 2.1401 0.8661 32.3446
BV-173 GDSC1; GDSC2; CTRP2 0.9532 2.2043 0.953 31.802
MEG-01 GDSC1; GDSC2 0.9675 2.2117 0.95 17.7861
SCC-3 GDSC2 0.9912 3.7353 -1.1202 4.6738
SEM CTRP2 1.0108 3.471 0.9861 33.6162
Karpas-45 GDSC1; GDSC2 1.0115 1.965 1.0073 17.4048
GR-ST GDSC1; GDSC2 1.0117 2.2096 0.9962 17.4461
CTV-1 GDSC1; GDSC2 1.0427 2.2566 1.0252 17.2203
ALL-PO GDSC1; GDSC2 1.0876 2.1252 1.0794 16.847
Hs 445 GDSC1; GDSC2 1.1081 2.8117 -0.6251 1.6708
JeKo-1 GDSC1; GDSC2 1.1137 2.9793 0.9962 20.0409
DG-75 GDSC1; GDSC2 1.2225 2.8234 1.145 16.1001
NKM-1 GDSC1; GDSC2 1.2634 2.6953 1.2103 15.6969
LAMA-84 GDSC1; GDSC2; CTRP2 1.2918 2.4209 1.2917 29.6865
KE-37 GDSC1; GDSC2; CTRP2 1.2994 2.7041 1.2987 29.6411
KOPN-8 GDSC1; GDSC2 1.4307 4.0688 -1.002 3.1948
CTB-1 GDSC1; GDSC2 1.4333 3.4286 1.2307 17.6254
NCI-H929 GDSC1; GDSC2; CTRP2 1.4748 3.0373 1.4725 28.5505
L-363 GDSC1; GDSC2; CTRP2 1.481 2.918 1.4798 28.508
Ku812 GDSC1; GDSC2 1.4891 2.803 1.4357 13.9998
Pfeiffer CTRP2 1.6463 2.4767 1.6463 29.301
RPMI-8866 GDSC1 1.7144 2.9343 1.6562 20.4668
KHM-1B CTRP2 1.7266 3.4992 1.719 28.7909
Ramos.2G6.4C10 GDSC1; GDSC2 1.7343 3.0889 1.6469 12.2892
Reh GDSC1; GDSC2; CTRP2 1.7373 3.312 1.7338 26.9147
CCRF-CEM GDSC1; GDSC2 1.7616 2.7084 1.7392 11.8286
KY821 GDSC1; GDSC2 1.7655 3.8479 1.4554 12.9757
KMOE-2 GDSC1; GDSC2 1.7706 2.8699 1.7275 11.8412
U-698-M GDSC1; GDSC2 1.7789 2.9374 1.7253 11.82
HL-60 GDSC1; GDSC2 1.7943 3.096 1.7105 11.8236
HAL-01 GDSC1; GDSC2 1.8414 3.3198 1.7067 11.675
BE-13 GDSC1; GDSC2 1.8545 3.3106 1.7235 11.5613
ATN-1 GDSC1; GDSC2 1.896 3.3609 1.7549 11.291
P30/OHK GDSC1; GDSC2 1.8984 4.2102 1.46 12.5338
SR GDSC1; GDSC2; CTRP2 1.928 3.8875 1.9105 25.7675
EB1 CTRP2 1.9423 4.0809 1.9139 27.4239
NOMO-1 GDSC1; GDSC2 1.9429 3.2418 1.8381 10.7906
WSU-NHL GDSC1; GDSC2 1.9738 3.8243 1.6883 11.3115
Loucy GDSC1; GDSC2 2.0013 3.7892 1.7306 11.0423
MOLM-16 GDSC1; GDSC2; CTRP2 2.0628 3.209 2.0623 26.5275
MOLT-3 CTRP2 2.0815 4.1162 2.0562 26.4861
OCI-AML-2 GDSC1; GDSC2; CTRP2 2.087 3.7695 2.0554 19.81
RS4;11 GDSC1; GDSC2; CTRP2 2.0886 4.4331 2.0375 24.8705
MM1.S GDSC1; GDSC2; CTRP2 2.1047 3.372 2.1034 24.6128
SU-DHL-5 GDSC1; GDSC2 2.115 3.2374 2.0268 9.4299
SKM-1 GDSC1; GDSC2; CTRP2 2.2383 3.4717 2.237 25.361
DEL GDSC1; GDSC2; CTRP2 2.239 2.8177 2.239 23.7699
Karpas-231 GDSC1; GDSC2 2.2431 3.4473 2.108 8.659
L-540 GDSC1; GDSC2; CTRP2 2.2709 3.2415 2.2708 23.5707
ST486 GDSC1; GDSC2 2.2778 3.4366 2.1492 8.3718
MHH-PREB-1 GDSC1; GDSC2 2.2829 4.6705 1.6632 10.4798
Farage GDSC1; GDSC2 2.2876 3.5569 2.1212 9.9229
MOLT-16 GDSC1; GDSC2; CTRP2 2.3032 3.3851 2.3027 23.3702
Mono-Mac-1 CTRP2 2.3061 6.4174 1.857 26.4603
SUP-B8 GDSC1; GDSC2 2.3366 3.9298 2.036 10.1669
EM-2 GDSC1; GDSC2; CTRP2 2.3503 3.7537 2.3464 23.0867
SU-DHL-1 GDSC2; CTRP2 2.3751 3.5536 2.3739 24.4495
TUR GDSC1; GDSC2 2.3806 3.6356 2.1946 7.8414
GA-10 GDSC1; GDSC2; CTRP2 2.3832 4.1085 2.3686 22.9148
Karpas-299 GDSC1; GDSC2; CTRP2 2.3872 3.2927 2.3871 22.8443
ALL-SIL GDSC1; GDSC2 2.3911 4.3888 1.8988 9.1059
CML-T1 GDSC1; GDSC2; CTRP2 2.3917 4.194 2.3728 22.8753
PL21 CTRP2 2.4579 4.8334 2.3823 24.1499
RPMI-8402 GDSC1; GDSC2; CTRP2 2.4652 3.9445 2.4586 22.3773
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 2.4721 4.1359 2.4587 23.8441
MOLT-4 GDSC1; GDSC2 2.4726 3.9487 2.1717 7.6503
Peer CTRP2 2.4844 3.6133 2.4834 23.7203
Daudi GDSC1; GDSC2 2.4875 3.5524 2.3393 6.8802
HDLM-2 GDSC1; GDSC2; CTRP2 2.492 5.5629 2.2876 22.85
BALL-1 GDSC1; GDSC2 2.5006 3.9563 2.198 7.4488
DoHH2 GDSC2 2.5373 3.2796 2.4768 8.1905
NB4 GDSC1; GDSC2; CTRP2 2.5454 3.8056 2.5428 23.3196
CRO-AP2 GDSC1; GDSC2 2.5555 3.7747 2.3296 7.8677
Sc-1 GDSC1 2.5615 3.2093 2.5199 6.9067
MOLP-8 GDSC1; GDSC2; CTRP2 2.5763 4.7676 2.5165 21.8521
SU-DHL-16 GDSC1; GDSC2 2.6428 3.357 2.5709 6.3332
HH [Human lymphoma] GDSC1; GDSC2 2.6629 3.6938 2.4755 5.7351
SU-DHL-10 GDSC1; GDSC2; CTRP2 2.6737 3.5095 2.6736 21.0545
JVM-3 GDSC1; GDSC2; CTRP2 2.6804 5.3882 2.5293 21.4988
SUP-M2 GDSC1; GDSC2; CTRP2 2.6981 3.5196 2.698 20.9026
MOLT-13 GDSC1; GDSC2; CTRP2 2.7044 4.9974 2.5034 16.2918
KMS-34 CTRP2 2.7158 5.4803 2.5489 22.7492
H9 GDSC1; GDSC2 2.7363 3.3806 2.6659 4.6883
SUP-T1 GDSC1; GDSC2; CTRP2 2.7467 3.9404 2.7442 20.6063
K-562 GDSC1; GDSC2 2.7525 3.3295 2.6984 4.4994
NALM-6 GDSC1; GDSC2; CTRP2 2.7624 4.0802 2.7574 20.5162
HC-1 GDSC1; GDSC2 2.7661 4.9256 2.0201 7.5106
Hs 611.T CTRP2 2.7704 5.9525 2.4961 22.7659
Namalwa GDSC1; GDSC2; CTRP2 2.7821 4.1672 2.775 20.3998
KMS-20 CTRP2 2.7899 3.9231 2.788 21.6883
OCI-AML-5 GDSC1; CTRP2 2.7971 4.1589 2.7905 21.656
JURL-MK1 GDSC1; CTRP2 2.7974 4.2329 2.7884 21.6622
EB2 GDSC1; GDSC2 2.8203 3.4684 2.7284 4.1479
BC-3 GDSC2 2.8355 3.8385 2.5962 6.2379
AML-193 CTRP2 2.8396 4.1803 2.8332 21.3721
OCI-Ly19 GDSC1; GDSC2; CTRP2 2.8517 5.7981 2.6241 22.0593
KYO-1 CTRP2 2.8909 4.4749 2.873 21.0692
RPMI-8226 GDSC1; GDSC2; CTRP2 2.9357 5.1557 2.8466 19.7024
YT GDSC1; GDSC2 2.9494 3.5613 2.8319 3.292
SU-DHL-6 GDSC1; GDSC2; CTRP2 2.9736 4.7332 2.9397 19.288
BONNA-12 GDSC2 2.9829 4.3481 2.5047 6.2525
Karpas-1106P GDSC1; GDSC2 2.9856 4.1756 2.5903 4.2848
Ri-1 CTRP2 2.9871 5.3853 2.8619 20.7971
GDM-1 GDSC1; GDSC2; CTRP2 3.0026 7.2882 1.9652 17.4965
Ki-JK CTRP2 3.0073 4.425 2.9957 20.2723
P32/ISH GDSC1; GDSC2 3.0082 3.7331 2.8193 3.1727
KMS-26 CTRP2 3.0091 4.3088 3.0022 20.2447
Karpas-422 GDSC1; GDSC2; CTRP2 3.0092 4.691 2.9807 19.0488
QIMR-WIL GDSC1; GDSC2 3.044 4.5944 2.4414 5.6677
KMS-21-BM CTRP2 3.0565 4.3216 3.0501 19.9273
NU-DUL-1 GDSC1; GDSC2; CTRP2 3.0608 4.7506 3.0297 19.9817
Kasumi-2 CTRP2 3.1051 5.0729 3.0403 19.8018
SUP-B15 GDSC1; GDSC2 3.1065 4.3914 2.5986 3.9353
HuT 78 CTRP2 3.1398 5.3846 3.0273 19.7358
KM-H2 GDSC1; GDSC2; CTRP2 3.142 6.0358 2.8793 18.9903
PF-382 GDSC1; GDSC2; CTRP2 3.1525 4.4736 3.1428 18.094
AMO1 GDSC1; GDSC2; CTRP2 3.1533 4.8903 3.1135 18.1846
LC4-1 GDSC1; GDSC2 3.1892 4.943 2.3983 4.6838
JJN-3 GDSC1; GDSC2; CTRP2 3.2217 4.4571 3.2143 17.6545
ML-2 GDSC1; GDSC2 3.2238 4.5627 2.618 3.5628
JSC-1 GDSC1; GDSC2 3.2364 5.1443 2.3386 4.8593
KE-97 CTRP2 3.2418 5.2924 3.1535 18.9726
A3/Kawakami GDSC1; GDSC2; CTRP2 3.2497 5.0648 3.1955 17.6286
MY-M12 GDSC1; GDSC2 3.2657 5.3059 2.2827 6.7446
VAL GDSC1; GDSC2 3.2754 4.7596 2.564 3.702
MLMA GDSC1; GDSC2 3.2886 4.8049 2.5525 3.7269
CA46 GDSC1; GDSC2; CTRP2 3.3407 5.5676 3.209 17.3129
RL GDSC1; GDSC2 3.4783 5.0068 2.606 3.6071
MHH-CALL-2 GDSC1; GDSC2 3.4881 5.3742 2.4308 3.8828
TK [Human B-cell lymphoma] GDSC1; GDSC2 3.5106 5.1005 2.5846 3.1109
PL-21 GDSC1; GDSC2 3.5138 6.6454 1.8173 7.9028
Jurkat GDSC1; GDSC2; CTRP2 3.5426 4.749 3.5312 15.6626
KMS-18 CTRP2 3.5734 14.4766 -0.3741 29.6189
DB GDSC1; GDSC2 3.5797 5.602 2.3889 3.8992
RCH-ACV GDSC1; GDSC2; CTRP2 3.5906 7.259 2.9588 18.6439
F-36P CTRP2 3.5964 5.7316 3.4513 16.8101
P31/FUJ GDSC1; GDSC2; CTRP2 3.6317 5.6412 3.5095 15.4647
P12-Ichikawa GDSC1; GDSC2; CTRP2 3.6683 5.004 3.6443 14.9176
KMS-27 CTRP2 3.7134 5.8511 3.5506 16.0942
U266B1 GDSC1; GDSC2; CTRP2 3.7136 5.3646 3.6489 14.7655
SIG-M5 GDSC2 3.7207 8.5583 1.0282 13.2053
L-428 GDSC1; GDSC2; CTRP2 3.7729 5.2332 3.7307 14.3222
HPB-ALL CTRP2 3.7772 5.3982 3.7119 15.3266
SU-DHL-4 GDSC1; GDSC2; CTRP2 3.7866 5.0625 3.7633 15.12
OCI-AML-3 GDSC1; GDSC2 3.7917 5.9755 2.3634 3.624
KO52 CTRP2 3.8124 6.1196 3.5877 15.6583
M-07e CTRP2 3.8237 5.2237 3.7858 14.9224
HEL GDSC1; GDSC2; CTRP2 3.8543 5.2716 3.8124 14.7325
LP-1 GDSC1; GDSC2; CTRP2 3.874 5.2771 3.8327 14.599
KCL-22 GDSC1; GDSC2; CTRP2 3.91 5.0528 3.8931 13.3855
WSU-DLCL2 GDSC1; GDSC2; CTRP2 3.918 5.4687 3.8519 13.4934
OCI-M1 GDSC1; GDSC2 3.9413 5.5399 2.6769 1.9465
SUP-T11 CTRP2 3.9427 5.8251 3.8067 14.4728
Granta-519 GDSC1; GDSC2; CTRP2 3.9453 6.2053 3.7078 13.8961
RPMI-6666 GDSC1; GDSC2; CTRP2 4.0076 5.6933 3.9067 13.0478
OCI-Ly3 CTRP2 4.1205 7.1807 3.5534 14.8965
WIL2 NS GDSC1; GDSC2 4.1234 5.8439 2.6498 1.8093
MHH-CALL-4 GDSC2; CTRP2 4.1443 6.4434 3.8495 13.7095
EHEB GDSC1; CTRP2 4.1868 6.6249 3.8334 13.646
EJM GDSC1; GDSC2; CTRP2 4.1873 6.6355 3.8302 12.8041
HD-MY-Z CTRP2 4.2438 5.8876 4.1198 12.426
CMK GDSC1; CTRP2 4.2536 5.9655 4.111 12.4273
HT GDSC1; GDSC2; CTRP2 4.3195 5.2832 4.3026 11.5484
JVM-2 GDSC1; GDSC2; CTRP2 4.3464 7.922 3.4786 13.6723
BC-1 GDSC1; GDSC2 4.3874 6.6002 2.4627 2.2587
DND-41 GDSC1; GDSC2; CTRP2 4.4004 6.2203 4.1994 10.9348
ROS-50 GDSC1; GDSC2 4.4052 6.148 2.6769 1.5922
L-1236 GDSC1; GDSC2 4.4233 6.6116 2.4791 2.1429
U-937 CTRP2 4.4737 6.2385 4.2736 11.1722
OCI-Ly10 CTRP2 4.4918 9.9186 2.6989 17.3064
Mono-Mac-6 GDSC1; GDSC2; CTRP2 4.5044 11.653 1.8721 19.2234
THP-1 GDSC1; GDSC2; CTRP2 4.6271 6.2794 4.4276 10.1509
SU-DHL-8 GDSC1; GDSC2; CTRP2 4.6343 5.9629 4.527 9.158
MN-60 GDSC1; GDSC2 4.6353 6.2987 2.7332 0.9258
ME1 GDSC1; GDSC2 4.716 6.0322 2.8782 0.4198
SK-MM-2 GDSC1; GDSC2; CTRP2 4.7318 6.6347 4.4165 9.2728
Raji GDSC1; GDSC2; CTRP2 4.7571 5.3399 4.753 8.0536
CESS GDSC1; GDSC2 4.8084 6.7606 2.6264 1.15
SUP-HD1 GDSC1; GDSC2; CTRP2 4.8214 6.8208 4.4395 8.9562
NK-92MI GDSC2 4.9734 7.0719 2.5787 1.5655
MOLP-2 CTRP2 5.0156 6.5176 4.7644 7.767
MC116 GDSC1; GDSC2; CTRP2 5.065 5.9196 5.0069 6.7257
P3HR-1 CTRP2 5.148 6.4814 4.9198 6.8034
ARH-77 GDSC1; GDSC2 5.2376 6.7841 2.8113 0.3373
MHH-CALL-3 CTRP2 5.2621 8.4188 4.1555 9.5904
IM-9 GDSC1; GDSC2 5.282 6.3959 2.9653 0.079
ME1 CTRP2 5.2862 7.2079 4.7527 7.0954
VL51 GDSC1; GDSC2 5.3679 7.6761 2.5214 1.0541
Jiyoye GDSC1; GDSC2 5.5387 7.5193 2.6594 0.5566
Toledo CTRP2 5.5801 9.8666 3.7338 10.6396
RC-K8 GDSC1; GDSC2 5.7252 7.0862 2.8862 0.0953
Karpas-620 GDSC1; GDSC2; CTRP2 6.3748 7.6653 5.4901 1.6543
REC-1 CTRP2 6.9042 10.087 4.6871 4.2437
BL-41 GDSC1; GDSC2; CTRP2 7.1766 8.1985 5.7021 0.2441
⏷ Show the Full List of 205 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC1; GDSC2 2.634 4.7683 1.968 8.1054
OACP4 C GDSC1; GDSC2 2.675 4.6143 2.0806 7.4754
TE-12 GDSC1; GDSC2 2.7524 5.0862 1.9295 9.3508
ESO-51 GDSC1; GDSC2 2.9243 3.9673 2.6283 4.2773
KYAE-1 GDSC1; GDSC2 3.0014 3.7296 2.814 3.2162
ESO-26 GDSC1; GDSC2 3.1171 4.1001 2.7513 3.192
SK-GT-4 GDSC1; GDSC2 3.1579 4.8078 2.4383 4.5679
OACM5.1 C GDSC1; GDSC2 3.2836 4.587 2.6572 3.241
KYSE-50 GDSC1; GDSC2 3.4804 5.0626 2.5799 3.1928
FLO-1 GDSC1; GDSC2 3.5428 5.7642 2.2796 4.4881
HCE-4 GDSC1; GDSC2 3.7424 7.8399 1.4031 9.6338
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 2.7864 3.6319 2.6311 4.6734
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-ME-N GDSC1; GDSC2 -0.2412 6.4295 -1.703 32.0629
SK-N-BE(2) CTRP2 1.4148 7.3204 0.5938 33.4136
TGW GDSC1; GDSC2 1.6026 3.0147 1.5197 13.262
NB69 GDSC1; GDSC2 1.9044 4.6462 1.2854 13.2835
CHP-134 GDSC2 1.9137 3.3665 -0.4763 0.3573
KP-N-SI9s CTRP2 2.2678 3.4737 2.2667 25.1639
SJNB-14 GDSC1; GDSC2 2.404 4.2583 1.9692 8.7529
SiMa GDSC1; GDSC2; CTRP2 2.5049 6.1209 2.1605 23.2354
SJNB-7 GDSC1; GDSC2 2.5243 7.4883 0.5417 14.9833
MHH-NB-11 GDSC2; CTRP2 2.6552 4.942 2.5779 22.8416
Kelly GDSC1; GDSC2; CTRP2 2.6736 5.0875 2.5759 21.3666
CHP-212 GDSC1; GDSC2 2.7938 4.7953 2.1093 7.0236
SK-N-SH GDSC1; GDSC2; CTRP2 3.0844 5.0435 3.0222 18.6869
KP-N-YS GDSC2 3.2047 6.6519 1.5582 11.4829
SJNB-13 GDSC1; GDSC2 3.229 5.5329 2.1381 5.8273
CHP-126 GDSC1; GDSC2; CTRP2 3.2463 5.704 3.0765 19.2285
NB1 GDSC1; GDSC2; CTRP2 3.3357 5.1202 3.2799 17.0967
NH-12 GDSC1; GDSC2 3.3385 6.4484 1.7724 7.3209
NB(TU)1 GDSC1; GDSC2 3.3392 4.4227 2.7859 2.5081
SJNB-10 GDSC1; GDSC2 3.4846 5.1011 2.564 3.2598
SK-N-MC-IXC GDSC1; GDSC2 3.5723 5.0153 2.6738 3.0195
SK-N-BE(2)-M17 GDSC1; GDSC2 3.5854 6.6646 1.8648 6.3652
SJNB-6 GDSC1; GDSC2 3.6116 6.3571 2.0385 6.4435
SJNB-12 GDSC1; GDSC2 3.6187 7.1435 1.6525 7.301
SK-N-AS GDSC1; GDSC2; CTRP2 3.751 6.0959 3.5273 15.0606
KP-N-RT-BM-1 GDSC2 3.7847 6.0968 2.2987 5.2506
GOTO GDSC1; GDSC2 3.8593 10.0416 0.3988 12.5975
SK-N-DZ GDSC1; GDSC2 4.0533 13.4604 -1.1514 18.5028
SK-N-FI GDSC1; GDSC2 4.061 6.0879 2.4957 2.574
SJNB-17 GDSC1; GDSC2 4.2247 6.8197 2.2561 4.5295
SJNB-5 GDSC1; GDSC2 4.2381 6.9016 2.226 4.1219
LA-N-6 GDSC1; GDSC2 4.2699 10.4821 0.4979 13.1487
IMR-5 GDSC1; GDSC2 5.6537 7.075 2.8648 0.1306
KP-N-YN GDSC1; GDSC2; CTRP2 7.5998 19.8692 0.3816 18.1862
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-28 CTRP2 1.4988 7.7596 0.5284 33.3134
SNU-478 CTRP2 4.2629 5.7155 4.1791 12.1567
SNU-1196 CTRP2 4.59 6.6284 4.2666 11.6646
HuCC-T1 GDSC1; GDSC2; CTRP2 5.1421 6.2513 4.9963 6.124
SNU-869 CTRP2 5.3013 6.1897 5.1896 5.3482
SNU-308 CTRP2 5.3284 6.864 4.9502 6.1981
SNU-245 CTRP2 5.5292 7.8822 4.6674 6.8657
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 88 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFM-223 GDSC1; GDSC2 0.7004 23.2996 -8.9277 40.6576
Hs 578T GDSC1; GDSC2; CTRP2 1.0683 8.9798 -0.3968 35.094
MDA-MB-415 GDSC1; GDSC2 1.5879 7.7731 -2.6558 12.2595
UACC-812 GDSC2 2.2313 3.7929 -0.5078 0.3023
DU4475 GDSC1; GDSC2; CTRP2 2.3293 3.2665 2.3292 23.2059
HCC2157 GDSC1; GDSC2 2.482 3.7169 2.2737 7.1777
Evsa-T GDSC1; GDSC2 2.7279 5.1886 1.8568 8.3709
CAL-120 GDSC1; GDSC2; CTRP2 2.9677 8.746 1.6978 23.5386
CAL-51 GDSC1; GDSC2; CTRP2 3.2027 5.4184 3.0889 18.1154
HCC1569 GDSC1; GDSC2 3.2796 5.2167 2.339 5.5869
HCC1599 GDSC2 3.3358 4.9457 2.5215 5.0276
HCC1187 GDSC1; GDSC2 3.3951 5.8807 2.103 5.6304
COLO 824 GDSC1; GDSC2 3.4017 6.0463 2.0256 5.9839
Hs 578Bst CTRP2 3.4291 6.426 3.0776 39.3276
KPL-1 CTRP2 3.4963 5.6759 3.3549 17.4634
MCF-7 GDSC1; GDSC2; CTRP2 3.6634 6.9393 3.1564 16.5889
MDA-MB-453 GDSC1; GDSC2; CTRP2 3.9661 9.8156 2.2347 19.1644
HMC-1-8 CTRP2 4.0916 5.4744 4.0375 13.194
HCC1954 GDSC1; GDSC2; CTRP2 4.1102 5.2479 4.0861 12.1578
OCUB-M GDSC1; GDSC2 4.1652 6.4186 2.4074 2.8114
CAL-85-1 GDSC1; GDSC2; CTRP2 4.1665 6.8967 3.7124 13.2769
MDA-MB-468 GDSC1; GDSC2; CTRP2 4.2048 5.4105 4.1676 11.6088
HCC1428 GDSC1; GDSC2 4.2325 6.0428 2.6246 1.7737
HCC202 GDSC1 4.4442 6.5996 2.497 2.3959
MDA-MB-175-VII GDSC1; GDSC2 4.5304 6.0623 2.7797 0.8537
HCC1500 GDSC1; GDSC2; CTRP2 4.5636 6.0313 4.4319 9.6813
MDA-MB-436 GDSC1; GDSC2 4.5868 6.2668 2.7221 1.007
AU565 GDSC1; GDSC2; CTRP2 4.6708 6.004 4.5561 8.955
CAL-148 GDSC2; CTRP2 4.7985 6.0864 4.673 8.195
BT-474 GDSC1; GDSC2; CTRP2 4.8015 5.7454 4.7564 7.908
YMB-1-E GDSC2 4.8713 6.6982 2.6835 1.2034
HCC1806 GDSC1; GDSC2; CTRP2 4.939 6.142 4.81 7.3311
MDA-MB-231 GDSC1; GDSC2; CTRP2 4.9657 6.5139 4.7123 7.6
BT-549 GDSC1; GDSC2; CTRP2 4.9787 10.127 3.0588 13.8234
HCC70 GDSC1; GDSC2 5.1285 7.2212 2.5928 1.0022
T-47D GDSC1; GDSC2; CTRP2 5.1695 7.25 4.6162 7.442
HCC1419 GDSC1; GDSC2 5.2297 6.55 2.893 0.1852
EFM-192A GDSC1; GDSC2 5.2972 7.0856 2.7226 0.5184
HDQ-P1 GDSC1; GDSC2; CTRP2 5.3053 7.088 4.8265 6.3297
ZR-75-30 GDSC1; GDSC2; CTRP2 5.3189 6.6911 5.0153 5.5941
BT-20 GDSC1; GDSC2; CTRP2 5.3197 8.4164 4.2111 8.6527
HCC1143 GDSC1; GDSC2; CTRP2 5.353 7.2218 4.8129 6.2691
HCC2218 GDSC1; GDSC2; CTRP2 5.3543 7.0067 4.9127 6.2812
ZR-75-1 CTRP2 5.3582 6.0075 5.3053 4.7555
CAMA-1 GDSC1; GDSC2; CTRP2 5.3729 6.1597 5.2771 4.5138
MDA-MB-361 GDSC1; GDSC2; CTRP2 5.3861 6.6837 5.0882 5.1584
JIMT-1 GDSC1; GDSC2; CTRP2 5.4015 6.1459 5.3127 4.3112
HCC1937 GDSC1; GDSC2; CTRP2 5.483 6.7981 5.1369 4.7415
MRK-nu-1 GDSC1; GDSC2 5.5491 7.0355 2.8406 0.1858
BT-483 GDSC1; GDSC2 5.554 7.0866 2.8244 0.2097
MDA-MB-157 GDSC1; GDSC2; CTRP2 5.9969 8.4064 4.8236 4.8978
HCC1395 GDSC1; GDSC2; CTRP2 6.1945 17.2133 0.5846 20.0226
UACC-893 GDSC1; GDSC2 6.2694 8.1935 2.6999 0.2626
MDA-MB-330 GDSC1; GDSC2 6.4026 9.3144 2.3401 1.092
HCC38 GDSC1; GDSC2; CTRP2 6.8618 14.4412 2.5063 12.3696
EFM-19 GDSC1; GDSC2 6.9886 16.6836 -0.606 11.3035
BT 440 CTRP2 -2.6657 2.4765 -2.7763 57.3787
BT 482 CTRP2 -0.9842 4.9213 -1.3512 47.1934
BT 504 CTRP2 2.5073 8.6661 1.2497 27.9107
BT 131 CTRP2 2.9518 4.3227 2.9431 20.6322
BT 286 CTRP2 3.0513 4.8649 3.0084 20.0852
BT 416 CTRP2 3.0649 4.534 3.0496 19.9012
BT 444 CTRP2 3.0953 7.5675 2.3116 22.4717
BT 139 CTRP2 3.0959 5.6237 2.9309 20.2125
BT 239 CTRP2 3.0994 5.3625 2.9876 20.0025
BT 330 CTRP2 3.1672 5.7698 2.975 19.8343
BT 231 CTRP2 3.7431 5.7758 3.6009 15.8236
BT 248 CTRP2 3.9709 12.8652 0.7823 25.3931
BT147 CTRP2 3.9799 5.9062 3.8275 14.2837
BT 245 CTRP2 4.1872 6.2797 3.9488 13.2165
BT164 CTRP2 4.19 10.5249 2.1186 20.2686
BT 359 CTRP2 4.4333 5.6327 4.379 10.9186
BT 340 CTRP2 4.464 5.9711 4.3391 10.9638
BT 333 CTRP2 4.5138 6.0489 4.3728 10.6903
BT 428 CTRP2 4.5378 5.2362 4.5323 10.0554
BT 216 CTRP2 4.5608 5.9108 4.4597 10.2346
BT 232 CTRP2 4.7609 5.9187 4.6759 8.8452
BT 172 CTRP2 4.8081 5.6635 4.7769 8.3425
BT 187 CTRP2 4.8169 6.7563 4.4603 9.4849
BT 159 CTRP2 4.9078 13.576 1.294 21.5065
BT 320 CTRP2 5.0478 6.1958 4.912 7.1211
BT 422 CTRP2 5.0534 6.0314 4.9664 6.906
BT 112 CTRP2 5.0725 8.5312 3.9207 10.9969
BT 328 CTRP2 5.1613 6.4403 4.9496 6.6521
BT 498 CTRP2 5.179 6.2059 5.0514 6.2196
BT 224 CTRP2 5.3536 13.3632 1.7945 18.77
BT 228 CTRP2 5.6869 17.4828 0.0246 23.7407
BT 179 CTRP2 8.2536 20.2531 0.6866 17.0771
⏷ Show the Full List of 88 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.2572 5.2879 4.2369 11.9751
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-172 GDSC1; GDSC2; CTRP2 -1.1239 7.3726 -2.1778 45.9527
D-263MG GDSC1; GDSC2 -0.7057 8.9802 -3.3019 37.6697
SNU-466 CTRP2 0.0089 4.1811 -0.143 40.6138
SNU-201 CTRP2 0.6027 6.0134 0.1142 40.2318
SNU-1105 CTRP2 0.7417 4.1664 0.6412 35.6471
D-245MG GDSC2 1.0799 6.9417 -0.5801 30.662
M059K CTRP2 1.595 8.8179 0.2258 33.8105
LNZTA3WT4 GDSC1 1.6242 9.6418 -1.3445 28.4745
SF539 GDSC1; GDSC2; CTRP2 1.7479 5.6344 1.4608 27.7556
42-MG-BA GDSC1; GDSC2; CTRP2 1.8113 4.7255 1.7065 26.774
D-392MG GDSC1; GDSC2 2.2849 4.3214 1.8189 9.7769
YH-13 GDSC1; GDSC2; CTRP2 2.4831 5.0507 2.3772 22.583
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 2.5549 8.8872 -0.1232 17.8325
KNS-60 CTRP2 2.5919 6.7845 2.0513 24.8989
SF126 GDSC1; GDSC2; CTRP2 2.7081 7.5881 1.8901 25.1245
H4 GDSC1; GDSC2 2.7952 4.8232 2.0972 7.0758
DK-MG GDSC1; GDSC2; CTRP2 2.7969 5.3169 2.6692 20.6948
D-336MG GDSC1; GDSC2 2.8644 5.2171 1.9704 8.7898
SNU-738 CTRP2 2.8709 7.0866 2.2494 25.0627
SW1088 GDSC1; GDSC2; CTRP2 3.0297 4.9716 2.9732 19.01
CAS-1 GDSC1; GDSC2; CTRP2 3.0907 7.9563 2.1534 21.6464
KINGS-1 GDSC1; GDSC2 3.1051 5.2944 2.1496 6.058
PFSK-1 GDSC1; GDSC2 3.1951 4.5479 2.6003 3.7136
CCF-STTG1 CTRP2 3.1994 7.195 2.5638 21.2401
SK-MG-1 GDSC1; GDSC2 3.2205 4.8365 2.4785 4.2319
MOG-G-UVW GDSC1; GDSC2 3.2326 5.9071 1.9542 6.6919
GaMG GDSC1; GDSC2; CTRP2 3.286 12.0465 0.5198 26.457
LN-18 GDSC1; GDSC2; CTRP2 3.3149 4.1544 3.3142 17.0515
SNU-489 CTRP2 3.3564 5.0925 3.3055 19.4199
KG-1-C CTRP2 3.3698 5.7582 3.1984 18.4121
GI-1 GDSC1; GDSC2 3.3895 7.0122 1.5328 8.3454
SF268 GDSC1; GDSC2; CTRP2 3.4374 9.2416 1.966 21.4084
D283 Med GDSC1; GDSC2; CTRP2 3.5086 6.4965 3.1415 17.0627
D-566MG GDSC1; GDSC2 3.5659 5.2231 2.5662 4.121
D-247MG GDSC1; GDSC2 3.6783 5.5361 2.4959 3.7676
D-542MG GDSC1; GDSC2 3.7539 5.3082 2.6617 2.7101
GB-1 GDSC1; GDSC2; CTRP2 3.8067 6.6303 3.4205 15.2734
LN-229 GDSC1; GDSC2; CTRP2 3.8599 5.071 3.8393 13.7101
AM-38 GDSC1; GDSC2; CTRP2 3.8934 5.5113 3.818 13.6772
TM-31 CTRP2 3.9595 7.2638 3.3498 16.1232
SNB-75 GDSC1; GDSC2; CTRP2 4.1032 5.8174 3.9833 13.3472
LN-405 GDSC1; GDSC2 4.1481 7.5214 1.8646 5.3121
NMC-G1 GDSC1; GDSC2; CTRP2 4.1728 5.2506 4.1517 12.5398
D-502MG GDSC1; GDSC2 4.1984 7.9772 1.6781 7.1338
KNS-81 CTRP2 4.2109 6.4181 3.9302 13.2148
T98G GDSC1; GDSC2; CTRP2 4.2167 5.8997 4.0874 11.8373
GOS-3 CTRP2 4.2972 7.6395 3.5502 14.4292
U-251MG GDSC1; GDSC2; CTRP2 4.4124 10.6556 2.2691 18.0091
D-423MG GDSC1; GDSC2 4.4372 9.9976 0.8618 10.9427
YKG-1 GDSC1; GDSC2; CTRP2 4.5115 5.684 4.4544 10.4076
M059J GDSC1; GDSC2 4.5221 9.781 1.0298 8.4877
U-118MG GDSC1; GDSC2; CTRP2 4.6443 6.4089 4.4033 9.5542
KNS-81-FD GDSC1; GDSC2 4.7149 10.0269 1.0475 9.4126
Daoy GDSC1; GDSC2; CTRP2 4.7171 6.6725 4.3863 9.4194
ONS-76 GDSC1; GDSC2; CTRP2 4.7337 5.7749 4.6776 8.3675
GMS-10 CTRP2 4.9231 8.1147 3.9724 11.1457
Becker GDSC1; GDSC2; CTRP2 4.9398 7.1919 4.4075 8.7755
KALS-1 GDSC1; GDSC2; CTRP2 4.9454 6.669 4.6311 7.9439
KNS-42 GDSC1; GDSC2; CTRP2 4.9722 5.9487 4.899 7.397
SF295 GDSC1; GDSC2; CTRP2 5.055 6.2509 4.9019 7.1371
U-87MG ATCC GDSC1; GDSC2; CTRP2 5.0554 6.2232 4.9115 6.6573
SNU-626 CTRP2 5.1393 6.2693 4.9872 6.5739
DBTRG-05MG GDSC1; GDSC2; CTRP2 5.4408 8.5589 4.2544 8.228
SW1783 GDSC1; GDSC2; CTRP2 5.5553 11.399 2.9493 13.0643
8-MG-BA GDSC1; GDSC2; CTRP2 5.5987 8.2197 4.5662 6.6857
Onda 11 GDSC1; GDSC2 5.6121 7.3721 2.7441 0.3944
Hs 683 GDSC1; GDSC2 5.6313 12.9254 0.2818 11.385
Onda 10 GDSC1; GDSC2 5.7911 7.3273 2.8271 0.1781
MOG-G-CCM GDSC1; GDSC2 5.9137 12.9551 0.4563 8.7157
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 2.9755 4.8027 2.2762 5.7768
ETK-1 GDSC1; GDSC2 3.3505 5.3805 2.3163 4.7131
TGBC1TKB GDSC1; GDSC2 5.3274 7.002 2.7667 0.3987
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 -3.3721 4.392 -3.8327 59.9212
AN3-CA GDSC1; GDSC2; CTRP2 -0.749 6.62 -1.5343 43.7288
MFE-296 GDSC1; GDSC2; CTRP2 2.7083 9.9275 0.9178 26.7538
JHUEM-3 CTRP2 3.0163 5.7726 2.8099 20.8888
HEC-1-A CTRP2 3.8043 5.7188 3.6804 15.3513
EN GDSC1; GDSC2; CTRP2 3.8602 5.7487 3.7345 14.0499
RL95-2 GDSC1; GDSC2; CTRP2 3.8977 5.3075 3.854 13.5476
HEC-151 CTRP2 4.5192 6.8748 4.0973 11.7039
HEC-50B CTRP2 4.6149 6.4434 4.3596 10.4389
HEC-59 CTRP2 4.7537 6.1759 4.5978 9.1491
HEC-6 CTRP2 4.8555 5.8214 4.8003 8.1105
HEC-1-B CTRP2 5.0402 6.5624 4.7736 7.6632
HEC-108 CTRP2 5.2642 5.8467 5.2376 5.2886
HEC-251 CTRP2 5.2864 6.5419 5.0431 5.946
KLE GDSC1; GDSC2; CTRP2 5.3589 7.1473 4.8532 6.1028
MFE-319 GDSC1; GDSC2; CTRP2 5.4884 5.978 5.4543 3.5836
EFE-184 CTRP2 5.504 6.1996 5.406 3.9518
HEC-265 CTRP2 5.7267 6.2813 5.6131 2.5371
MFE-280 GDSC1; GDSC2 6.4096 12.19 1.1202 5.2957
ESS-1 GDSC1; GDSC2; CTRP2 6.5574 17.8105 0.5832 19.3662
Ishikawa (Heraklio) 02 ER- CTRP2 6.0303 7.4397 5.335 3.0093
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-704 GDSC1; GDSC2 0.1469 7.1135 -3.4351 20.0412
LB1047-RCC GDSC1; GDSC2 1.7086 4.2824 1.2301 16.5746
NCC010 GDSC1; GDSC2 2.8859 4.4322 2.3718 6.5275
KTCTL-13 GDSC1; GDSC2 3.0614 4.1843 2.6581 4.4246
UO-31 GDSC1; GDSC2; CTRP2 3.2605 5.7219 3.0879 19.1436
KMRC-3 CTRP2 3.3164 5.9032 3.1046 18.9111
HA7-RCC GDSC1; GDSC2 3.3399 4.6539 2.6709 3.5822
SN12C GDSC1; GDSC2 3.3644 7.7189 1.1587 10.1619
LB2241-RCC GDSC1; GDSC2 3.3702 6.0049 2.0204 7.1293
RXF 393L GDSC1; GDSC2 3.383 9.1878 0.4397 15.5939
KTCTL-140 GDSC1; GDSC2 3.5991 5.1418 2.6314 3.1945
BB65-RCC GDSC1; GDSC2 3.6121 5.2261 2.5995 3.3414
ACHN GDSC1; GDSC2; CTRP2 3.6784 6.2209 3.412 15.6584
TK-10 GDSC1; GDSC2 3.8052 5.7083 2.5036 2.9501
KTCTL-26A GDSC1; GDSC2 3.8717 5.5835 2.61 2.7614
BFTC-909 GDSC1; GDSC2; CTRP2 3.9628 5.3553 3.917 13.1478
SW13 GDSC1; GDSC2 3.9994 7.0545 1.9857 5.0113
CAL-54 GDSC1; GDSC2; CTRP2 4.1353 6.5177 3.8148 12.9994
KMRC-20 GDSC1; GDSC2; CTRP2 4.1902 5.7046 4.1025 11.8647
LB996-RCC GDSC1; GDSC2 4.466 6.483 2.5623 1.7462
OS-RC-2 GDSC1; GDSC2; CTRP2 4.4865 6.9235 4.0435 11.2521
VMRC-RCW GDSC2; CTRP2 4.5516 6.079 4.4057 10.4568
TUHR4TKB CTRP2 4.6962 6.1878 4.5315 9.5636
786-O GDSC1; GDSC2; CTRP2 4.7243 6.5666 4.4336 9.2319
KMRC-2 CTRP2 4.7398 13.4849 1.1879 22.2458
NCC021 GDSC1; GDSC2 4.8165 12.8294 -0.251 15.4531
SW156 GDSC1; GDSC2 4.9027 7.0119 2.5682 1.494
SNU-1272 CTRP2 4.9147 6.4287 4.6887 8.3407
TUHR10TKB CTRP2 5.0377 6.3422 4.8521 7.3732
KMRC-1 GDSC1; GDSC2; CTRP2 5.109 11.5376 2.484 15.7158
769-P GDSC1; GDSC2; CTRP2 5.1729 6.3229 5.005 6.0098
A-498 GDSC1; GDSC2; CTRP2 5.2611 7.4458 4.6179 7.221
KTCTL-195 GDSC1; GDSC2 5.3359 7.1347 2.7202 0.5052
Caki-2 CTRP2 5.5296 9.4589 3.8912 10.0922
KTCTL-21 GDSC1; GDSC2 5.932 8.535 2.4371 1.0961
RCC10RGB GDSC1; GDSC2; CTRP2 5.9764 11.8923 3.0636 11.8257
TUHR14TKB CTRP2 6.0664 24.6022 -3.2162 30.14
KTCTL-1M GDSC1; GDSC2 6.8916 8.8362 2.7006 0.1373
Caki-1 GDSC1; GDSC2; CTRP2 9.597 21.3203 1.1261 13.6596
VMRC-RCZ GDSC1; GDSC2; CTRP2 10.6464 23.8619 0.6174 13.1519
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H716 GDSC1; GDSC2; CTRP2 -10.2225 -1.5126 -10.3513 84.0338
KM12 GDSC1; GDSC2; CTRP2 -0.0209 5.0815 -0.339 38.7142
COLO 320HSR GDSC1; GDSC2 2.3135 3.7258 2.0897 8.5046
HT-55 GDSC1; GDSC2; CTRP2 2.9151 4.9048 2.8597 19.7222
SW48 GDSC1; GDSC2; CTRP2 2.9462 4.6742 2.9161 19.4472
HCT 15 GDSC1; GDSC2 3.0633 5.2721 2.1237 6.2798
LoVo GDSC1; GDSC2; CTRP2 3.2306 5.0144 3.1814 17.7316
SNU-C1 GDSC1; GDSC2 3.246 5.0108 2.4134 4.4825
SNU-175 GDSC2; CTRP2 3.4037 7.1278 2.808 18.5139
SNU-C2B GDSC1; GDSC2 3.5224 6.3696 1.9617 6.0345
SK-CO-1 GDSC1; GDSC2; CTRP2 3.5985 5.1737 3.5527 15.4233
SW626 GDSC1; GDSC2 3.6662 5.6165 2.4474 3.4599
DiFi GDSC1; GDSC2 3.7022 5.8188 2.3745 3.7348
SNU-1040 GDSC1; GDSC2 3.7139 5.2485 2.6625 2.7848
HT115 GDSC1; GDSC2; CTRP2 3.7604 4.4979 3.7596 15.2188
OUMS-23 CTRP2 3.9111 5.0738 3.8926 15.3324
SW837 GDSC1; GDSC2 3.9326 6.0538 2.4254 3.0956
CaR-1 GDSC1; GDSC2 3.9384 6.5952 2.1663 4.2804
SNU-283 GDSC2 3.9712 5.9873 2.4838 3.6894
COLO 320 CTRP2 4.0581 6.2874 3.8058 14.1256
C2BBe1 GDSC1; GDSC2; CTRP2 4.0824 6.01 3.9125 12.8113
SW948 GDSC1; GDSC2; CTRP2 4.1066 5.9337 2.5977 2.0573
SNU-1033 CTRP2 4.158 6.468 3.8563 13.6443
LS513 GDSC1; GDSC2; CTRP2 4.1588 5.0025 4.1532 12.5806
SNU-C2A CTRP2 4.1631 6.0528 3.989 13.1425
T84 GDSC1; GDSC2; CTRP2 4.1637 5.4968 4.1114 11.9143
NCI-H747 GDSC1; GDSC2; CTRP2 4.1687 5.6427 4.0914 11.9643
SNU-61 GDSC1; GDSC2; CTRP2 4.2302 5.8013 4.1252 11.6718
LS1034 GDSC1; GDSC2; CTRP2 4.331 6.4329 4.0556 11.6242
GP5d GDSC1; GDSC2 4.3563 6.0368 2.6988 1.3238
LS180 GDSC1; GDSC2; CTRP2 4.3607 5.4649 4.3267 10.6249
COLO201 CTRP2 4.4094 6.055 4.2571 11.4256
HT-29 GDSC1; GDSC2; CTRP2 4.4263 5.317 4.4116 10.1537
SNU-503 CTRP2 4.4314 8.118 3.4784 14.3617
COLO 678 GDSC1; GDSC2 4.4708 7.9108 1.8999 4.6187
SNU-81 GDSC1; GDSC2 4.4929 7.3109 2.1984 3.8214
SNU-407 GDSC1; GDSC2; CTRP2 4.5114 6.4674 4.2394 10.4896
CL-11 GDSC1; GDSC2; CTRP2 4.5811 6.5703 4.2783 10.1645
COLO205 GDSC1; GDSC2; CTRP2 4.6521 5.3865 4.6419 8.7287
SW1417 GDSC1; GDSC2 4.6556 6.5857 2.6217 1.3098
CCK-81 GDSC1; GDSC2; CTRP2 4.7271 7.2575 3.6634 6.4479
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2 4.8206 6.739 4.4711 8.8444
LS411N GDSC1; GDSC2; CTRP2 4.8882 5.7685 4.8458 7.3577
SW1116 GDSC1; GDSC2; CTRP2 4.9246 6.2084 4.7738 7.4958
SW620 GDSC1; GDSC2; CTRP2 4.9681 7.4968 4.3012 9.1032
NCI-H508 GDSC1; GDSC2; CTRP2 5.0725 6.7 4.7534 7.6513
SNU-C5 GDSC1; GDSC2; CTRP2 5.1487 6.9785 4.7156 7.1214
HCT 116 GDSC1; GDSC2; CTRP2 5.2571 5.9403 5.2112 5.0662
SW1463 GDSC1; GDSC2 5.2761 7.0179 2.7395 0.4867
RKO GDSC1; GDSC2; CTRP2 5.426 6.4046 5.2457 4.4826
MDST8 GDSC1; GDSC2; CTRP2 5.4473 6.0071 5.4026 3.8754
HCC2998 GDSC1; GDSC2 5.4913 13.3184 -0.0042 11.2964
HCT 8 CTRP2 5.5191 6.246 5.4057 3.9097
DLD-1 CTRP2 5.5643 6.228 5.4609 3.5724
LS123 GDSC1; GDSC2; CTRP2 5.6174 6.2866 5.4955 3.0856
SNU-C4 CTRP2 5.6644 6.1396 5.6003 2.7611
CW-2 GDSC1; GDSC2; CTRP2 5.6786 6.8706 5.2974 3.6804
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 2.4396 3.3958 2.3379 7.0455
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-886 CTRP2 -1.6724 11.5757 -4.3387 50.7795
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 -1.2711 3.7494 -1.4499 48.8281
Li-7 CTRP2 -1.1092 6.3918 -1.8601 48.1266
Huh-7 GDSC1; GDSC2 0.1617 6.0265 -1.113 28.7016
JHH-7 GDSC1; GDSC2 0.3938 5.1221 -0.4972 25.6044
HuH-6 CTRP2 1.5274 5.4606 1.2611 30.9792
SNU-182 CTRP2 2.1913 4.4332 2.1456 25.8237
SNU-423 GDSC1; GDSC2 2.2521 3.4363 2.1212 8.5741
Hep-G2 CTRP2 2.779 5.399 2.6339 22.2521
SNU-761 CTRP2 3.0166 4.6929 2.2026 4.9832
HuH-1 GDSC1; GDSC2; CTRP2 3.2498 5.4305 3.1375 17.8166
SK-HEP-1 GDSC1; GDSC2; CTRP2 3.5215 5.2531 3.4599 15.9549
Hep-G2/C3A GDSC1; GDSC2 3.6028 9.4868 0.4703 12.8142
SNU-387 GDSC1; GDSC2; CTRP2 4.0117 7.0727 3.4798 14.515
HLF CTRP2 4.0202 9.1252 2.6074 18.8386
JHH-1 GDSC1; GDSC2; CTRP2 4.2393 5.1484 4.2289 11.3081
SNU-475 CTRP2 4.3227 12.4607 1.3086 22.8256
HLE GDSC1; GDSC2 4.7215 9.6421 1.2386 7.2019
SNU-878 CTRP2 4.7411 5.8594 4.668 8.9353
JHH-5 CTRP2 4.8179 7.4761 4.1578 10.666
JHH-2 GDSC1; GDSC2; CTRP2 5.057 8.7573 3.7973 10.8196
SNU-398 GDSC1; GDSC2; CTRP2 5.1979 11.4453 2.6097 15.0645
PLC/PRF/5 CTRP2 5.3851 5.9493 5.3485 4.5185
JHH-6 GDSC1; GDSC2; CTRP2 5.6377 5.925 5.6265 2.5761
JHH-4 GDSC1; GDSC2; CTRP2 6.1224 19.9609 -0.8489 24.0802
SNU-449 GDSC1; GDSC2; CTRP2 6.567 11.6152 3.6817 8.3969
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LC-1F CTRP2 -2.8639 19.0575 -13.2205 43.6092
NCI-H2795 GDSC1; GDSC2 -2.249 4.5586 -3.1354 43.6446
NCI-H2810 GDSC1; GDSC2 -0.8006 6.1467 -2.172 44.3481
SBC-3 GDSC1; GDSC2 -0.6629 6.7836 -2.2919 35.2615
NCI-H1581 GDSC1; GDSC2; CTRP2 0.7259 13.4296 -2.6632 40.0569
NCI-H2227 GDSC1; GDSC2 0.797 7.4307 -1.0873 30.4911
NCI-H1876 GDSC1; GDSC2 0.8148 2.6015 0.7435 19.1434
Lu-135 GDSC1; GDSC2 1.4726 2.8981 1.4016 14.1927
NCI-H82 GDSC1; GDSC2 1.4793 2.6318 1.4489 13.9839
COR-L51 CTRP2 1.4939 6.4665 0.9569 32.0631
COR-L311 GDSC2 1.6806 4.7138 -1.1474 3.5889
CPC-N GDSC1; GDSC2 1.7932 3.168 1.693 11.8976
NCI-H446 GDSC1; GDSC2; CTRP2 1.8707 8.725 0.5547 30.177
NCI-H520 GDSC1; GDSC2; CTRP2 1.9393 10.2983 -0.034 31.5774
NCI-H524 GDSC1; GDSC2 2.093 3.1348 2.0269 9.5066
NCI-H838 GDSC1; GDSC2; CTRP2 2.1766 5.9428 1.8507 26.8879
LXF 289 GDSC1; GDSC2; CTRP2 2.226 4.7377 2.1477 24.0996
NCI-H1341 GDSC1; GDSC2; CTRP2 2.3 6.6507 1.7777 25.1019
NCI-H1184 CTRP2 2.3585 4.7848 2.2827 24.8125
NCI-H209 GDSC1; GDSC2 2.383 3.9086 2.0935 8.2685
Ms-1 GDSC1; GDSC2 2.4161 3.6206 2.2383 7.5403
DMS 114 GDSC1; GDSC2; CTRP2 2.4489 11.9768 -0.2719 30.7634
LK-2 GDSC1; GDSC2 2.5779 12.4733 -1.8877 24.3792
NCI-H2731 GDSC1; GDSC2 2.6027 5.6277 1.5259 10.237
Lu-134-A GDSC1; GDSC2 2.6432 4.7767 1.9729 9.4557
Lu-99A GDSC1; GDSC2 2.7879 5.3774 1.8211 8.3831
SK-LU-1 GDSC1; GDSC2; CTRP2 2.8003 5.2392 2.6869 20.6266
NCI-H211 GDSC1; GDSC2; CTRP2 2.8391 4.4576 2.8204 20.0802
A-549 GDSC1; GDSC2; CTRP2 2.8867 4.4333 2.871 19.7731
NCI-H720 GDSC1; GDSC2 2.8963 3.3829 2.8395 3.4308
LC-2/ad GDSC1; GDSC2 2.9291 5.4458 1.9171 8.8946
A-427 GDSC1; GDSC2 2.9462 13.8744 -2.2706 27.5278
NCI-H2171 GDSC2 2.9585 3.8689 2.7077 5.093
NCI-H1048 GDSC1; GDSC2 2.9654 8.3715 0.4942 14.1295
NCI-H1792 GDSC1; GDSC2; CTRP2 2.977 4.1048 2.9744 19.1683
NCI-H835 GDSC1; GDSC2 3.0275 4.3986 2.5221 4.4928
NCI-H2141 GDSC1; GDSC2 3.0523 3.9913 2.7426 3.4017
COR-L23 GDSC1; GDSC2 3.0737 5.5266 2.0065 6.8096
NCI-H1693 GDSC1; GDSC2 3.116 6.4607 1.5778 8.7403
NCI-H187 GDSC1 3.1192 4.3129 2.6488 4.3043
NCI-H1304 GDSC1 3.1224 5.2751 2.1744 6.9244
Lu-99 CTRP2 3.1296 5.5142 2.9909 19.8954
NCI-H23 GDSC1; GDSC2; CTRP2 3.2018 5.6692 3.036 18.2925
COR-L32 GDSC1; GDSC2 3.22 9.818 -0.0114 15.7738
NCI-H2803 GDSC1; GDSC2 3.2354 11.7655 -0.9722 24.4961
COR-L88 GDSC1; GDSC2 3.255 4.4215 2.7154 3.0293
NCI-H2347 GDSC1; GDSC2 3.3245 5.2645 2.3528 4.5966
IST-SL2 GDSC1; GDSC2 3.3257 6.4753 1.7484 7.4628
SK-MES-1 GDSC1; GDSC2; CTRP2 3.3268 4.9103 3.2944 17.0774
NCI-H290 GDSC1; GDSC2 3.3454 5.3661 2.3194 5.527
NCI-H1993 GDSC1; GDSC2 3.369 7.3613 1.3413 9.2939
IST-SL1 GDSC1; GDSC2 3.3709 4.6045 2.721 3.2256
SBC-1 GDSC1; GDSC2 3.4105 4.4024 2.8536 2.3921
NCI-H2110 GDSC1; GDSC2; CTRP2 3.4208 5.585 3.2922 17.9211
NCI-H2373 GDSC1; GDSC2 3.4442 8.4873 0.8404 11.4695
NCI-H1666 GDSC1; GDSC2; CTRP2 3.4676 5.5623 3.3477 16.4816
NCI-H1963 GDSC1; GDSC2 3.4851 5.4173 2.4069 4.002
NCI-H2009 GDSC1; GDSC2; CTRP2 3.4926 6.3425 3.1728 16.9993
CAL-12T GDSC1; GDSC2; CTRP2 3.4943 5.545 3.3801 17.3812
NCI-H1694 GDSC1; GDSC2; CTRP2 3.5049 5.0543 3.4675 15.9809
HCC44 GDSC1; GDSC2; CTRP2 3.562 5.3904 3.4818 15.7624
NCI-H2722 GDSC1; GDSC2 3.5755 6.6674 1.8555 6.429
RERF-LC-MS GDSC1; GDSC2; CTRP2 3.6031 5.8474 3.4312 16.8611
NCI-H3122 GDSC1; GDSC2 3.6154 5.4778 2.4778 3.4123
LCLC-97TM1 GDSC1; GDSC2; CTRP2 3.6277 6.2826 3.3383 16.0533
HCC33 GDSC2 3.64 7.9593 1.2627 12.0369
SW1271 GDSC1; GDSC2; CTRP2 3.6518 5.5325 3.5531 15.2622
NCI-H1703 GDSC1; GDSC2; CTRP2 3.6681 6.0622 3.4462 15.5714
COR-L321 GDSC1; GDSC2 3.6695 4.9214 2.7901 2.1837
NCI-H1563 GDSC1; GDSC2; CTRP2 3.6716 5.8808 3.4977 15.388
HCC15 GDSC1; GDSC2; CTRP2 3.6986 5.6338 3.5837 15.023
NCI-H1770 GDSC1; GDSC2 3.7105 5.7306 2.4241 4.0923
NCI-H345 GDSC1; GDSC2 3.7294 4.9895 2.7984 2.0245
NCI-H1437 GDSC1; GDSC2 3.7394 5.5559 2.5308 3.9176
NCI-H2023 GDSC1; GDSC2; CTRP2 3.7451 5.762 3.6062 14.8125
NCI-H2106 CTRP2 3.7542 5.4624 3.6765 15.5231
NCI-H2461 GDSC1; GDSC2 3.7584 6.4951 2.0828 4.9981
NCI-H292 GDSC1; GDSC2; CTRP2 3.7617 5.5555 3.6677 15.5296
EBC-1 GDSC1; GDSC2; CTRP2 3.7632 5.217 3.7224 14.3783
NCI-H2405 GDSC1; GDSC2; CTRP2 3.8125 5.7631 3.6793 14.373
DMS 454 CTRP2 3.8134 8.8798 2.5099 19.7509
PC-14 GDSC1; GDSC2; CTRP2 3.8289 6.0402 3.6277 14.4983
NCI-H64 GDSC1; GDSC2 3.8502 5.7486 2.5156 2.8188
LB647-SCLC GDSC1; GDSC2 3.8638 5.9589 2.4232 4.2946
NCI-H2081 GDSC1; GDSC2; CTRP2 3.8652 5.7072 3.749 14.9185
NCI-H1155 GDSC1; GDSC2; CTRP2 3.8679 5.6764 3.7586 13.9478
NCI-H526 GDSC1; GDSC2; CTRP2 3.8717 5.723 3.7527 13.956
NCI-H1568 GDSC1; GDSC2 3.8825 6.9226 1.9648 5.3201
NCI-H847 GDSC1; GDSC2 3.9047 5.586 2.631 2.2067
RERF-LC-KJ GDSC1; GDSC2 3.9051 7.0198 1.9336 5.424
NCI-H1755 GDSC1; GDSC2; CTRP2 3.9285 9.2625 2.4527 18.4661
NCI-H522 GDSC1; GDSC2; CTRP2 3.9622 10.9338 1.7039 21.0442
NCI-H146 GDSC1; GDSC2 3.9643 5.4901 2.715 2.0484
COR-L303 GDSC2 3.9655 6.6914 2.1387 5.8124
NCI-H2087 GDSC1; GDSC2; CTRP2 4.005 6.1765 3.7813 13.477
DMS 79 GDSC1; GDSC2; CTRP2 4.0201 5.4876 3.9585 13.696
ABC-1 GDSC1; GDSC2 4.0202 6.0856 2.4697 3.2314
EPLC-272H GDSC1; GDSC2; CTRP2 4.0293 7.6759 3.2556 15.2801
EMC-BAC-2 GDSC1; GDSC2 4.0335 5.9782 2.5297 2.4637
HOP-62 GDSC1; GDSC2; CTRP2 4.041 6.1172 3.8378 13.1826
NCI-H69 GDSC1; GDSC2; CTRP2 4.0451 5.4806 3.9865 12.6754
NCI-H727 GDSC1; GDSC2; CTRP2 4.0456 5.8382 3.9157 12.907
NCI-H358 GDSC1; GDSC2; CTRP2 4.0481 6.8725 3.5944 14.0107
NCI-H647 GDSC1; GDSC2; CTRP2 4.0549 6.9407 3.5762 14.9931
NCI-H1734 GDSC1; GDSC2; CTRP2 4.0558 5.6853 3.9606 13.5757
NCI-H1944 GDSC1; GDSC2; CTRP2 4.0617 6.1715 3.8446 13.1007
NCI-H2122 GDSC1; GDSC2; CTRP2 4.0664 5.8195 3.9428 12.7561
NCI-H250 GDSC2 4.0938 6.9211 2.1179 5.647
NCI-H1092 GDSC1; GDSC2 4.125 6.5022 2.341 3.1704
HCC95 CTRP2 4.1292 6.0173 3.9617 14.3334
NCI-H1373 CTRP2 4.1606 6.0517 3.9866 13.1589
RERF-LC-Sq1 GDSC1; GDSC2 4.1679 7.1451 2.0612 4.3737
NCI-H1623 GDSC1; GDSC2 4.172 6.382 2.4291 2.7048
HCC1588 CTRP2 4.1973 5.1423 4.1857 12.3444
NCI-H661 GDSC1; GDSC2; CTRP2 4.2075 6.8359 3.7791 12.9311
ChaGo-K-1 GDSC1; GDSC2 4.2352 6.1197 2.591 2.244
NCI-H650 GDSC1; GDSC2; CTRP2 4.3068 6.5811 3.9785 11.9598
COLO 699 CTRP2 4.3228 5.8219 4.2213 11.8203
NCI-H510A GDSC1; GDSC2 4.3664 7.8848 1.8414 6.721
HCC2279 CTRP2 4.3929 5.6612 4.3304 11.2163
RERF-LC-A1 CTRP2 4.3943 6.8522 3.9729 12.5281
IA-LM GDSC1; GDSC2; CTRP2 4.4141 6.744 4.0349 11.4729
Calu-3 GDSC1; GDSC2; CTRP2 4.4273 5.3053 4.4135 10.1443
EMC-BAC-1 GDSC1; GDSC2 4.4359 7.012 2.302 3.3852
LOU-NH91 GDSC1; GDSC2; CTRP2 4.4398 6.4573 4.1653 10.944
MOR/CPR CTRP2 4.4446 5.2412 4.4359 10.6873
NCI-H2170 GDSC1; GDSC2; CTRP2 4.4466 8.82 3.173 14.575
Calu-6 GDSC1; GDSC2; CTRP2 4.449 5.8113 4.3609 10.2501
NCI-H1355 GDSC1; GDSC2; CTRP2 4.459 6.8454 4.0445 11.3201
NCI-H2126 CTRP2 4.4861 6.242 4.286 11.0898
HCC1833 CTRP2 4.5007 6.6026 4.18 11.4417
NCI-H1435 GDSC1; GDSC2; CTRP2 4.5068 6.6285 4.1772 10.7212
RERF-LC-Ad2 CTRP2 4.5186 7.2549 3.9432 12.3012
NCI-H1573 GDSC1; GDSC2; CTRP2 4.534 6.6098 4.2132 10.5212
HCC2108 CTRP2 4.5386 7.2841 3.9519 12.2134
NCI-H1915 GDSC1; GDSC2; CTRP2 4.5461 6.2619 4.3451 10.027
NCI-H2085 GDSC1; GDSC2; CTRP2 4.5477 7.5628 3.8424 11.8311
NCI-H841 GDSC1; GDSC2; CTRP2 4.5569 6.3407 4.3315 10.0442
NCI-H1838 GDSC1; GDSC2; CTRP2 4.5591 5.9273 4.4538 9.6203
LC-1/sq GDSC1; GDSC2 4.5681 6.8995 2.434 2.1503
Lu-65 GDSC1; GDSC2; CTRP2 4.5889 5.7913 4.5172 9.3226
NCI-H2804 GDSC1; GDSC2 4.6171 13.3498 -0.6578 19.3939
VMRC-LCD GDSC1; GDSC2; CTRP2 4.6224 6.1072 4.4749 9.3679
NCI-H810 GDSC1; GDSC2 4.6348 6.2628 2.7479 0.8754
NCI-H1385 CTRP2 4.6364 5.5894 4.6039 9.4906
NCI-H1975 GDSC1; GDSC2; CTRP2 4.6432 8.0938 3.7033 12.1198
NCI-H1869 GDSC1; GDSC2; CTRP2 4.6601 7.458 4.0038 10.9575
NCI-H740 GDSC2 4.6841 7.0176 2.4479 2.6084
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 4.7072 6.3218 4.5008 9.0422
Lu-139 GDSC1 4.7115 7.6373 2.183 3.5479
NCI-H2172 GDSC1; GDSC2; CTRP2 4.7294 6.0688 4.6026 9.2052
HCC827 GDSC1; GDSC2; CTRP2 4.7309 7.0406 4.2545 9.8597
NCI-H748 GDSC2 4.7663 7.3462 2.3479 3.0202
LCLC-103H GDSC1; GDSC2; CTRP2 4.7807 5.595 4.757 7.9689
NCI-H1650 GDSC1; GDSC2; CTRP2 4.7862 6.4687 4.5359 8.7044
NCI-H1781 GDSC1; GDSC2 4.794 6.3496 2.7882 0.6278
HCC366 GDSC1; GDSC2; CTRP2 4.7992 6.6231 4.4929 9.4097
NCI-H2444 GDSC1; GDSC2; CTRP2 4.8052 5.8161 2.994 0.1586
NCI-H2286 CTRP2 4.8334 5.9255 4.7533 8.3456
NCI-H1436 GDSC1; GDSC2 4.834 6.8111 2.6181 1.3576
HOP-92 GDSC1; GDSC2; CTRP2 4.8375 7.0863 4.3469 9.2526
DMS 53 GDSC1; GDSC2; CTRP2 4.8565 5.7242 4.8193 7.5388
NCI-H2228 GDSC1; GDSC2; CTRP2 4.8802 6.3936 4.6639 8.0002
HCC1195 CTRP2 4.9109 8.7093 3.68 12.3629
NCI-H1105 GDSC1; GDSC2; CTRP2 4.9379 6.2243 4.7833 7.9206
SHP-77 GDSC1; GDSC2; CTRP2 4.9386 5.7824 4.8977 7.0382
HCC2935 CTRP2 4.9995 6.0002 4.9158 7.2531
Calu-1 CTRP2 5.0033 6.8862 4.6041 8.4192
DMS 273 GDSC1; GDSC2; CTRP2 5.0047 6.9808 4.5655 8.0317
NCI-H1836 GDSC1; GDSC2 5.0064 6.6988 2.7459 0.7239
RERF-LC-Ad1 CTRP2 5.0246 6.3431 4.8377 7.4649
NCI-H2369 GDSC1; GDSC2 5.0613 13.8442 -0.5694 14.321
BEN GDSC1; GDSC2; CTRP2 5.0635 5.7942 5.0304 6.6478
NCI-H2029 GDSC1; GDSC2; CTRP2 5.073 6.267 4.9161 7.0316
COR-L105 GDSC1; GDSC2; CTRP2 5.1578 7.4614 4.5079 7.8773
NCI-H2591 GDSC1; GDSC2 5.1723 16.7574 -1.923 18.9643
LC-1/sq-SF CTRP2 5.1776 6.5664 4.9182 6.7268
NCI-H226 GDSC1; GDSC2; CTRP2 5.1961 12.1667 2.2504 16.3957
T3M-10 CTRP2 5.2088 7.6808 4.4565 8.4839
NCI-H889 CTRP2 5.2114 6.1275 5.1114 5.9025
NCI-H1688 GDSC1; GDSC2 5.2272 7.2548 2.6255 0.8296
NCI-H1299 GDSC1; GDSC2; CTRP2 5.2379 7.1458 4.7323 6.8435
HCC78 GDSC1; GDSC2; CTRP2 5.2473 6.4715 5.0296 5.7248
Sq-1 CTRP2 5.2763 6.583 5.0158 6.0793
NCI-H196 GDSC1; GDSC2; CTRP2 5.2888 6.6849 4.9866 5.7749
COR-L95 GDSC1 5.2971 6.7717 2.8393 0.3044
NCI-H2342 GDSC1; GDSC2; CTRP2 5.3122 6.6384 5.0306 5.5546
NCI-H1651 GDSC1; GDSC2; CTRP2 5.3146 6.3881 5.1334 5.1766
NCI-H1339 CTRP2 5.3188 9.9792 3.4438 12.4008
NCI-H2291 GDSC1; GDSC2; CTRP2 5.3392 6.6949 5.0348 5.8357
COR-L279 GDSC1; GDSC2 5.3468 6.7399 2.8696 0.1918
NCI-H441 GDSC1; GDSC2; CTRP2 5.3595 9.8821 2.8829 8.4878
NCI-H2066 GDSC1; GDSC2 5.363 7.387 2.6345 0.7178
PaCa-3 GDSC1; GDSC2 5.3791 7.4868 2.6025 0.7995
NCI-H2196 GDSC2 5.38 8.3584 2.2414 2.6928
HCC1171 CTRP2 5.3834 9.796 3.5928 11.6455
UMC-11 GDSC1; GDSC2 5.3836 7.0117 2.7857 0.3349
EKVX GDSC1; GDSC2; CTRP2 5.4136 7.5347 4.7251 6.8964
NCI-H322M GDSC1; GDSC2 5.4342 7.5872 2.5876 0.8082
NCI-H1395 CTRP2 5.4511 6.8476 5.0824 5.3564
NCI-H2030 GDSC1; GDSC2; CTRP2 5.4826 7.0921 5.0013 5.6047
Lu-165 GDSC1; GDSC2 5.4853 6.866 2.8764 0.1489
SBC-5 GDSC1; GDSC2; CTRP2 5.4925 5.9432 5.4664 3.5317
NCI-H322 CTRP2 5.5027 9.0964 4.0464 9.5044
NCI-H2818 GDSC1; GDSC2 5.5359 15.2638 -0.9195 14.8056
NCI-H2135 GDSC1; GDSC2 5.6562 7.1169 2.8513 0.1727
NCI-H1648 GDSC1; GDSC2 5.6616 7.8872 2.5708 0.7216
KNS-62 GDSC1; GDSC2; CTRP2 5.695 6.9476 5.2765 3.7242
NCI-H460 GDSC1; GDSC2; CTRP2 5.7308 6.4127 5.561 2.7313
NCI-H3255 GDSC1; GDSC2 5.8475 7.3167 2.8508 0.1337
HCC1438 CTRP2 6.0171 14.7194 1.6841 17.7867
NCI-H2595 GDSC1; GDSC2 6.0691 7.9719 2.7037 0.2676
NCI-H2869 GDSC1; GDSC2 6.2257 15.3528 -0.4793 13.6284
NCI-H513 GDSC1; GDSC2 6.2332 8.0207 2.7467 0.1686
COLO 668 GDSC1; GDSC2 6.5608 8.1809 2.8063 0.0682
SW1573 GDSC1; GDSC2; CTRP2 6.6614 9.1001 4.9953 3.1427
NCI-H596 GDSC1; GDSC2 8.1424 20.345 -1.5857 13.0768
NCI-H1793 GDSC1; GDSC2; CTRP2 11.4419 26.5194 -0.1197 14.2327
Hs 888.Lu CTRP2 2.8659 7.3808 2.1369 23.775
⏷ Show the Full List of 219 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 4.7383 6.5496 2.6797 1.0238
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -0.3797 5.4743 -0.8193 43.6294
A2780 GDSC1; GDSC2; CTRP2 -1.2724 5.9867 -1.9249 46.4068
COV434 CTRP2 1.5437 5.1608 1.3426 30.6561
OVCAR-5 GDSC1; GDSC2; CTRP2 3.0677 5.3494 2.9558 18.9521
ES-2 GDSC1; GDSC2 3.1536 4.642 2.5168 4.2068
IGROV-1 GDSC1; GDSC2; CTRP2 3.3898 8.7015 2.1543 20.8676
SNU-840 CTRP2 3.6391 5.8508 3.4696 16.6127
SK-OV-3 GDSC1; GDSC2; CTRP2 3.6482 5.8305 3.4845 15.4998
JHOS-4 GDSC1; GDSC2 3.6788 5.231 2.646 2.946
OVCAR-8 GDSC1; GDSC2; CTRP2 3.9601 6.1868 3.7293 13.7808
COV362 CTRP2 4.0255 8.6652 2.8212 17.9961
OV7 CTRP2 4.0416 7.0572 3.5177 15.2527
SNU-119 CTRP2 4.0568 5.7319 3.9519 13.6032
COV644 CTRP2 4.1002 7.8307 3.264 16.0725
JHOS-2 GDSC1; GDSC2; CTRP2 4.1322 6.6897 3.7516 14.1102
OVK18 GDSC1; GDSC2; CTRP2 4.1411 5.5891 4.0715 12.9178
FU-OV-1 GDSC1; GDSC2; CTRP2 4.1757 10.1283 2.2933 18.4613
OAW28 GDSC1; GDSC2; CTRP2 4.2708 6.5467 3.9517 12.1516
EFO-27 GDSC1; GDSC2; CTRP2 4.4671 6.7897 4.0745 11.9369
TYK-nu GDSC1; GDSC2; CTRP2 4.501 6.6169 4.1752 10.7438
OVTOKO GDSC1; GDSC2; CTRP2 4.6129 7.3995 3.9802 11.1615
DOV13 GDSC1; GDSC2; CTRP2 4.6809 5.9623 4.578 8.8525
OVCAR-4 GDSC1; GDSC2; CTRP2 4.8494 16.4675 -0.1937 24.8897
RMG-I GDSC1; GDSC2; CTRP2 4.9055 6.7102 4.5726 8.2583
MCAS CTRP2 5.068 6.6009 4.7882 7.5297
OVISE GDSC1; GDSC2; CTRP2 5.073 5.9299 5.0133 6.2612
SNU-8 CTRP2 5.0892 6.3256 4.9136 6.9941
JHOC-5 CTRP2 5.1047 6.2011 4.9722 6.7311
OVSAHO CTRP2 5.1256 5.846 5.0881 6.2497
OC 314 GDSC1; GDSC2; CTRP2 5.1634 8.5828 3.9827 9.8731
Caov-3 GDSC2; CTRP2 5.2026 6.9796 4.7705 7.2376
Kuramochi GDSC1; GDSC2; CTRP2 5.2264 6.178 5.112 5.4904
TOV-21G GDSC1; GDSC2; CTRP2 5.3045 6.2163 5.1841 5.0248
ES2 CTRP2 5.3333 6.2128 5.2166 5.1543
HEY A8 CTRP2 5.355 6.4696 5.1447 5.3655
OVCAR-3 GDSC1; GDSC2 5.3715 6.8298 2.8469 0.2227
EFO-21 GDSC1; GDSC2; CTRP2 5.3786 9.3269 3.8199 10.0489
ONCO-DG-1 CTRP2 5.3953 6.6151 5.127 5.325
OAW42 GDSC1; GDSC2; CTRP2 5.4023 10.364 3.3286 11.9088
OV56 GDSC1; GDSC2; CTRP2 5.4628 5.9517 5.4323 3.7313
OV-90 GDSC1; GDSC2; CTRP2 5.6089 6.1575 5.534 2.9716
Caov-4 GDSC1; GDSC2 6.0067 7.8382 2.7277 0.2456
OVKATE GDSC1; GDSC2 6.0345 7.5 2.8539 0.0853
JHOM-1 CTRP2 6.2034 18.5366 -0.0697 22.9679
TOV-112D GDSC1; GDSC2; CTRP2 8.7767 20.11 1.1382 14.0755
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 2.8563 5.8708 2.6109 22.0918
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 5.2516 6.1147 5.1591 5.6079
Yamato-SS CTRP2 5.6302 6.1187 5.5701 2.9728
STS-0421 GDSC1; GDSC2 -4.1356 17.317 -10.5642 54.4639
TTC-709 CTRP2 -0.7808 8.2204 -2.0943 46.7243
A-204 GDSC1; GDSC2; CTRP2 0.1804 8.6248 -1.2073 39.6965
G-401 GDSC1; GDSC2 0.3854 7.4592 -1.5129 29.3285
Rh18 GDSC1; CTRP2 0.6769 4.6354 0.5025 36.2975
G-402 GDSC1; GDSC2; CTRP2 0.9547 6.7762 0.274 33.7876
Rh41 GDSC1; GDSC2; CTRP2 0.9572 4.0832 0.8797 32.0177
Hs 729.T CTRP2 1.6849 7.3308 0.8824 31.6557
Tm87-16 CTRP2 2.0313 4.4566 1.9746 26.9266
Rh30 GDSC1; GDSC2 2.2129 6.0699 0.9414 13.9668
TE 441.T GDSC2; CTRP2 2.27 3.9824 2.2578 25.1862
EW-8 GDSC1; GDSC2 2.2903 4.6759 1.6684 10.4352
Hs 633.T GDSC1; GDSC2 2.4388 4.0043 2.1133 8.0101
BT-16 CTRP2 2.8755 4.4612 2.8579 21.1707
SW982 GDSC1; GDSC2; CTRP2 3.0476 5.5313 2.8984 19.2003
MES-SA GDSC1; GDSC2; CTRP2 3.0614 6.7782 2.5626 20.3001
GCT GDSC1; GDSC2; CTRP2 3.4047 5.5337 3.2853 16.8728
RD GDSC1; GDSC2; CTRP2 3.4485 6.474 3.0834 17.43
SK-LMS-1 GDSC1; GDSC2; CTRP2 3.5422 8.0516 2.5893 18.9301
HT-1080 GDSC1; GDSC2; CTRP2 3.7626 6.5224 3.409 15.4346
VA-ES-BJ GDSC1; GDSC2 4.1119 7.0118 2.0866 4.3506
BT-12 CTRP2 4.272 5.0548 4.2671 11.8245
KYM-1 GDSC1; GDSC2; CTRP2 4.4196 12.3507 1.4524 20.8538
SW684 GDSC1; GDSC2 4.6852 5.8659 2.9286 0.3079
MFH-ino GDSC1; GDSC2 4.7035 7.1114 2.417 2.0584
SW872 GDSC1; GDSC2 4.7211 6.4816 2.6996 0.9694
RKN GDSC1; GDSC2; CTRP2 5.4625 6.0022 5.4204 3.7719
SK-UT-1 GDSC1; GDSC2; CTRP2 6.1808 13.9844 2.1875 14.721
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2 1.7138 6.6158 1.1507 28.8456
MPP 89 GDSC1; GDSC2; CTRP2 1.9376 8.235 0.8194 29.204
NCI-H28 GDSC1; GDSC2; CTRP2 3.3179 5.2074 3.2486 17.2513
IST-Mes1 GDSC1; GDSC2; CTRP2 3.4239 4.6837 3.4122 16.4053
ACC-MESO-1 CTRP2 3.4818 7.4755 2.7589 19.7054
NCI-H2452 GDSC1; GDSC2; CTRP2 4.4724 11.1547 2.0845 18.5406
NCI-H2052 GDSC1; GDSC2; CTRP2 5.1325 8.0796 4.1939 9.1301
JL-1 CTRP2 5.4571 9.4344 3.8381 10.4694
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2 4.2478 6.144 2.5875 1.9109
22Rv1 GDSC1; GDSC2; CTRP2 4.6098 6.9484 4.1644 10.4967
PC-3 GDSC1; GDSC2 4.7313 9.2728 1.4233 6.3536
DU145 GDSC1; GDSC2; CTRP2 4.7636 7.9828 3.8747 11.1911
LNCaP clone FGC GDSC1; GDSC2 4.9014 6.9459 2.5954 1.1777
NCI-H660 GDSC2 5.0099 6.4476 2.8441 0.4796
PaCa-3 CTRP2 5.6395 6.4485 5.4516 3.4022
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 3.0578 4.7959 3.0224 20.0163
A-253 GDSC1; GDSC2; CTRP2 5.3544 7.0857 4.8769 6.024
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 2.9835 8.4985 0.4465 16.6341
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 GDSC1; GDSC2; CTRP2 -7.0605 9.4853 -9.3256 65.0603
KATO III GDSC1; GDSC2; CTRP2 -6.7034 16.1992 -11.5285 60.6886
HSC-39 GDSC1; GDSC2 -6.4901 -4.4096 -6.4902 73.6683
ECC10 GDSC1; GDSC2; CTRP2 -0.9814 3.995 -1.1764 44.2419
Fu97 GDSC1; GDSC2; CTRP2 1.6523 7.5592 0.7663 30.2071
GSS CTRP2 1.7544 6.0831 1.3519 29.933
HGC-27 GDSC1; GDSC2; CTRP2 2.4886 4.6737 2.4344 22.3823
SCH GDSC1; GDSC2 3.0308 5.67 1.8972 8.7163
OCUM-1 GDSC1; GDSC2; CTRP2 3.1916 5.1078 3.1278 18.0224
TMK-1 GDSC1; GDSC2 3.3079 5.0783 2.432 5.6752
MKN28 GDSC1; GDSC2 3.3155 5.3998 2.2777 4.9727
RF-48 GDSC1; GDSC2 3.6608 5.2856 2.6062 2.7271
TGBC11TKB GDSC1; GDSC2 3.766 5.4991 2.5775 2.676
SNU-620 CTRP2 3.8423 4.5759 3.8414 14.6739
KE-39 CTRP2 3.9867 6.3851 3.6973 14.7361
GSU CTRP2 4.0479 4.6029 4.0477 13.3015
IM95 GDSC1; GDSC2; CTRP2 4.0925 6.402 3.8068 13.1449
23132/87 GDSC1; GDSC2; CTRP2 4.0937 6.4517 3.7918 13.1936
SNU-5 GDSC1; GDSC2; CTRP2 4.2383 5.4181 4.2023 11.3958
SNU-216 CTRP2 4.2885 6.7083 3.9132 13.0544
SNU-719 CTRP2 4.3707 6.328 4.1332 11.9942
ECC12 GDSC2; CTRP2 4.3921 6.187 4.2004 12.5497
NCI-N87 GDSC1; GDSC2; CTRP2 4.5373 5.8939 4.4382 9.7355
SNU-601 CTRP2 4.6047 5.9664 4.4938 9.9776
Hs 746.T GDSC1; GDSC2; CTRP2 4.6253 5.8957 4.5337 9.1615
SNU-668 CTRP2 4.6549 6.1356 4.5021 9.7947
NUGC-4 GDSC1; GDSC2; CTRP2 4.7544 5.8721 4.6796 8.2996
NUGC-3 GDSC1; GDSC2; CTRP2 4.7676 8.2396 3.7604 11.6129
MKN1 GDSC1; GDSC2; CTRP2 4.8841 6.6734 4.5643 8.3438
GCIY GDSC1; GDSC2 4.8938 7.0698 2.5391 1.3868
MKN74 CTRP2 5.0581 6.8184 4.6896 7.9383
SH-10-TC CTRP2 5.2556 8.4992 4.1105 9.7908
RERF-GC-1B GDSC1; GDSC2 5.3293 20.5941 -3.7036 23.7454
AGS GDSC1; GDSC2; CTRP2 5.5017 6.4383 5.3122 4.047
MKN7 GDSC1; GDSC2; CTRP2 5.5521 6.6164 5.2883 4.0099
MKN45 GDSC1; GDSC2; CTRP2 5.6512 6.0263 5.6201 2.5577
SNU-1 GDSC1; GDSC2 5.7952 7.5618 2.7463 0.273
SK-GT-2 GDSC1; GDSC2 6.2376 8.1212 2.7135 0.2116
SNU-1077 CTRP2 2.9712 8.4599 1.8216 24.601
SNU-685 CTRP2 4.1594 6.5638 3.8252 13.7559
SNG-M GDSC1; GDSC2; CTRP2 5.1335 6.6364 4.8435 6.691
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -0.5996 3.2142 -0.6735 44.4191
CGTH-W-1 GDSC1; GDSC2; CTRP2 1.5707 3.5432 1.5585 27.9824
WRO GDSC1; GDSC2 1.943 9.0885 -0.7781 22.0794
TT GDSC1; GDSC2; CTRP2 2.3549 5.1374 2.2243 23.4638
K5 GDSC1; GDSC2 2.7427 3.8311 2.5034 5.3677
B-CPAP GDSC1; GDSC2; CTRP2 2.7484 4.2838 2.736 20.6266
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 2.7949 10.5925 0.7079 28.7635
8305C GDSC1; GDSC2; CTRP2 2.9218 5.3368 2.8004 19.8943
IHH-4 GDSC1; GDSC2 3.2245 4.0839 2.857 2.4299
KMH-2 GDSC1; GDSC2 3.3962 4.5176 2.7848 2.8083
HTC-C3 GDSC1; GDSC2 3.4829 7.5285 1.3512 9.0036
BHT-101 GDSC1; GDSC2; CTRP2 3.658 5.7958 3.5035 15.408
ASH-3 GDSC1; GDSC2 4.131 6.1554 2.5094 2.4097
8505C GDSC1; GDSC2; CTRP2 4.3464 5.7341 4.2658 10.866
CAL-62 GDSC1; GDSC2; CTRP2 4.7855 6.6773 4.4576 8.9843
FTC-238 CTRP2 5.0233 6.3084 4.8482 7.4295
TT2609-C02 GDSC1; GDSC2; CTRP2 5.0311 7.3098 4.449 8.3992
FTC-133 GDSC1; GDSC2; CTRP2 6.057 7.1821 5.4861 2.1776
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-8 CTRP2 -1.0308 4.8429 -1.3853 47.4634
PCI-06A GDSC1; GDSC2 1.6667 3.6599 1.4131 15.8178
PCI-38 GDSC1 1.7153 4.0455 1.3289 16.0507
PCI-04B GDSC1; GDSC2 1.9638 4.4065 1.4486 14.5309
KON GDSC1; GDSC2 2.0315 4.3241 1.5537 13.7464
YD-10B CTRP2 2.4121 5.1161 2.2898 24.6154
KOSC-2 GDSC1; GDSC2 2.594 4.3433 2.1253 8.7996
Ca9-22 GDSC1; GDSC2 2.6098 5.7232 1.4862 10.4037
DOK GDSC1; GDSC2 2.8023 4.5542 2.2329 6.4281
BB49-HNC GDSC1; GDSC2 2.8482 10.3839 -0.6112 19.1275
SNU-46 CTRP2 2.9409 5.7932 2.7226 21.4325
JHU-011 GDSC1; GDSC2 2.9883 4.7703 2.3039 6.5891
NCI-H3118 GDSC1; GDSC2 3.0318 4.5514 2.4514 4.8132
BB30-HNC GDSC1; GDSC2 3.0869 4.6335 2.4612 5.4337
CAL-33 GDSC1; GDSC2; CTRP2 3.1275 5.2431 3.0386 18.5037
LB771-HNC GDSC1; GDSC2 3.1359 4.5216 2.5608 4.0416
OSC-20 GDSC1; GDSC2 3.146 5.8862 1.8904 7.1911
BICR 78 GDSC1; GDSC2 3.2118 5.5811 2.0993 6.0505
HO-1-N-1 GDSC1; GDSC2 3.252 5.4473 2.2004 5.48
PCI-15A GDSC1; GDSC2 3.3134 4.4779 2.7368 3.2823
SKN-3 GDSC1; GDSC2 3.3202 6.8085 1.5772 8.2856
JHU-022 GDSC1; GDSC2 3.3222 4.9085 2.5288 3.7655
SAT [Human HNSCC] GDSC1; GDSC2 3.3351 5.6242 2.1818 5.3854
BICR 22 GDSC1; GDSC2 3.3882 4.6114 2.7316 2.6622
HO-1-u-1 GDSC1; GDSC2 3.4241 4.8275 2.6525 2.9629
SAS GDSC1; GDSC2 3.4478 5.8909 2.1408 5.3402
BICR 31 GDSC2; CTRP2 3.4533 6.03 3.2206 18.0755
SNU-1214 CTRP2 3.4943 5.6744 3.353 17.4763
HSC-2 GDSC1; GDSC2; CTRP2 3.603 7.5453 2.8601 17.8025
SCC-9 GDSC1; GDSC2; CTRP2 3.6787 5.8872 3.5038 15.3467
SNU-1076 CTRP2 3.7019 5.498 3.6137 17.0869
SCC-25 GDSC1; GDSC2; CTRP2 3.7551 4.9087 3.7419 15.2957
OSC-19 GDSC1; GDSC2 3.8938 5.7341 2.5527 3.0252
BHY GDSC1; GDSC2; CTRP2 3.9309 5.0391 3.9159 15.1023
Detroit 562 GDSC1; GDSC2; CTRP2 3.9858 5.4581 3.9264 13.0484
JHU-029 GDSC1; GDSC2 4.0103 5.8916 2.5555 2.7971
BICR 10 GDSC1; GDSC2 4.0604 14.515 -1.6717 20.3196
HSC-3 GDSC1; GDSC2; CTRP2 4.3096 5.7083 4.2312 11.0884
SNU-899 CTRP2 4.346 5.6222 4.2867 11.5177
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 4.4242 7.2098 3.8627 12.8698
CAL-27 GDSC1; GDSC2; CTRP2 4.5992 7.3254 3.9976 11.1313
PCI-30 GDSC1; GDSC2 4.6593 11.7199 0.1787 11.9967
BICR 6 CTRP2 4.8408 9.4793 3.2437 14.3016
UPCI-SCC-090 GDSC1; GDSC2 4.9485 6.7352 2.7051 0.7766
BICR 16 CTRP2 4.9604 13.6004 1.3289 21.2693
HSC-4 GDSC1; GDSC2; CTRP2 5.2511 9.9741 3.3847 12.0003
SNU-1041 CTRP2 5.3988 7.4889 4.7326 6.9009
SCC-4 GDSC1; GDSC2; CTRP2 5.426 7.044 4.9676 5.5138
PE/CA-PJ41 (clone D2) CTRP2 5.4397 6.7979 5.0931 5.3429
SNU-1066 CTRP2 5.5998 7.4127 4.9617 5.4885
BICR 56 CTRP2 7.4296 9.0986 5.4589 0.7573
SCC-15 GDSC1; GDSC2 7.5177 18.4245 -1.0844 12.2605
FaDu GDSC1; GDSC2; CTRP2 8.3865 18.1228 1.8284 12.3894
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-1 CTRP2 -6.7233 6.687 -8.07 68.3966
JMSU-1 CTRP2 -5.0051 2.6261 -5.2822 71.1772
RT-112 GDSC1; GDSC2; CTRP2 -1.1342 9.2443 -2.8485 46.446
SW780 GDSC1; GDSC2 3.2302 8.8778 0.4672 13.6433
BC-3C CTRP2 3.7237 6.6263 3.3319 16.8618
TCCSUP GDSC1; GDSC2; CTRP2 3.806 5.4135 3.7404 14.1909
5637 GDSC1; GDSC2; CTRP2 3.8064 7.0475 3.2699 15.8054
647V GDSC1; GDSC2; CTRP2 4.0086 7.3498 3.3675 14.9271
253J CTRP2 4.0998 5.2687 4.0729 13.0459
U-BLC1 CTRP2 4.1009 5.4717 4.0479 13.1283
BFTC-905 GDSC1; GDSC2; CTRP2 4.2091 5.5076 4.1584 11.6258
CAL-29 GDSC1; GDSC2; CTRP2 4.3797 5.9203 4.26 10.7882
VM-CUB-1 CTRP2 4.4061 5.9877 4.2717 11.3832
639V GDSC1; GDSC2; CTRP2 4.4191 5.2588 4.4083 10.1861
HT-1376 GDSC1; GDSC2; CTRP2 4.577 8.0747 3.6452 12.4948
SCaBER CTRP2 4.5864 6.642 4.2577 10.9039
KU-19-19 GDSC1; GDSC2; CTRP2 4.6057 7.1576 4.0748 10.8325
J82 GDSC1; GDSC2; CTRP2 4.6655 11.9973 1.853 18.937
HT-1197 GDSC1; GDSC2 4.8562 13.4425 -0.5236 14.5203
253J-BV CTRP2 4.9788 5.7935 4.9391 7.2348
T24 GDSC1; GDSC2; CTRP2 5.1288 7.0483 4.6646 7.8489
KMBC-2 CTRP2 5.2636 8.0252 4.3465 8.802
UM-UC-3 GDSC1; GDSC2; CTRP2 5.7884 6.8728 5.4014 3.0388
SW1710 GDSC1; GDSC2; CTRP2 6.0658 12.8008 2.684 13.1026
RT-4 GDSC1; GDSC2; CTRP2 7.4103 23.8686 -1.7565 23.9719
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW962 GDSC1; GDSC2 -1.1297 6.0885 -2.4963 42.5972
NEC8 GDSC1; GDSC2 -0.2839 5.66 -1.4298 31.3429
NCC-IT GDSC2 0.0186 3.2369 -1.6029 10.0788
NT2-D1 GDSC1; GDSC2 0.5826 6.0508 -0.6866 25.7268
SKN GDSC1; GDSC2 1.6448 4.7539 0.9698 15.4595
HeLa GDSC1; GDSC2; CTRP2 1.7171 4.9079 1.5766 27.476
PA-1 GDSC1; GDSC2 1.7642 2.9942 1.6989 11.9769
BPH-1 GDSC1; GDSC2 2.0337 6.0805 0.7628 15.2667
DSH1 GDSC1; GDSC2 2.5349 4.5386 1.977 8.339
SiSo GDSC1; GDSC2 2.6305 3.699 2.439 5.9949
MS751 GDSC1; GDSC2 2.6795 3.9433 2.3898 6.0611
C-4-I GDSC1; GDSC2 2.7791 3.6794 2.6044 4.8123
PWR-1E GDSC1; GDSC2 2.9058 13.3738 -2.0548 24.125
HEY GDSC1; GDSC2 2.9905 4.3562 2.508 4.6539
Ca Ski GDSC1; GDSC2 3.001 5.191 2.1081 6.5042
ME-180 GDSC1; GDSC2 3.0448 5.1968 2.1446 6.2257
SW954 GDSC1; GDSC2 3.0613 7.8977 0.8134 14.5332
TC-YIK GDSC1; GDSC2 3.0725 4.875 2.3289 5.289
CAL-39 GDSC1; GDSC2 3.1475 5.8208 1.9243 7.0269
HT-3 GDSC1; GDSC2 3.2052 4.6272 2.5697 3.835
JAR GDSC1; GDSC2 3.2321 4.3482 2.7322 3.5238
HEC-1 GDSC1; GDSC2 3.3892 4.913 2.5818 3.3707
SKG-IIIa GDSC1; GDSC2 3.4929 5.6739 2.2852 4.5624
OVCA433 GDSC1; GDSC2 3.5089 6.4495 1.9111 7.3944
C-33 A GDSC1; GDSC2 3.5162 5.2991 2.4902 3.5456
SiHa GDSC1; GDSC2 3.5347 5.0024 2.6518 2.7474
KGN GDSC1; GDSC2 3.5708 11.0284 -0.3259 16.3176
OVMIU GDSC1; GDSC2 3.9232 6.2274 2.3347 3.5277
LB831-BLC GDSC1; GDSC2 3.9907 9.2199 0.91 10.0245
ACC-OV7 GDSC1; GDSC2 4.0887 6.6259 2.257 4.2353
DoTc2 4510 GDSC1; GDSC2 4.1172 6.015 2.5664 2.1792
JHOS-3 GDSC1; GDSC2 4.1176 7.088 2.0537 5.2707
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 4.1453 6.1496 2.5213 2.7424
OV17R GDSC1; GDSC2 4.1982 8.8817 1.2342 9.5136
PEO1 GDSC1; GDSC2 4.4858 6.6798 2.4852 2.0392
OVCA420 GDSC1; GDSC2 5.1274 7.1438 2.6238 0.9038
UWB1.289 GDSC1; GDSC2 5.7152 7.9088 2.5855 0.7677
SW756 GDSC1; GDSC2 5.7179 7.2563 2.8253 0.1693
JEG-3 GDSC1; GDSC2 5.9481 12.0204 0.9179 7.8227
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7707).
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Cancer Res. 2012 Apr 15;72(8):2045-56.
4 Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells. Oncogene. 2016 Aug 25;35(34):4518-28. doi: 10.1038/onc.2015.511. Epub 2016 Feb 8.