Details of the Drug

General Information of Drug (ID: DM3EP8N)

Drug Name
Dothiepin
Synonyms
Dothiepin; cis-dothiepin; Dosulepin; Prothiaden; UNII-CZ377VWX9P; Dosulepin [INN]; 113-53-1; CZ377VWX9P; CHEBI:36802; Dosulepin (INN); Dosulepin chloride; 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine; Dosulepine [INN-French]; Dosulepinum [INN-Latin]; Dosulepina [INN-Spanish]; Dothep; HSDB 7181; N,N-dimethyldibenzo[b,e]thiepin-Delta(11(6H),gamma)-propylamine; 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine; Dothiepin;; EINECS 204-031-2; Prothiadiene; Depresym
Indication
Disease Entry ICD 11 Status REF
Major depressive disorder 6A70.3 Approved [1]
ATC Code
N06AA16: Dothiepin
N06AA: Non-selective monoamine reuptake inhibitors
N06A: ANTIDEPRESSANTS
N06: PSYCHOANALEPTICS
N: NERVOUS SYSTEM
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C19H21NS
Canonical SMILES
CN(C)CCC=C1C2=CC=CC=C2CSC3=CC=CC=C31
InChI
InChI=1S/C19H21NS/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3/b17-11-
InChIKey
PHTUQLWOUWZIMZ-BOPFTXTBSA-N
Cross-matching ID
PubChem CID
5282426
ChEBI ID
CHEMBL36802
CAS Number
25627-38-7
UNII
W13O82Z7HL
DrugBank ID
DB09167
TTD ID
D0Q2MN
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Drug Pharmacogenomic Perturbation (DPP)NEW Click to Jump to the Detailed DPP Information of This Drug
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7549).