Details of the Drug

General Information of Drug (ID: DM3H0IX)

Drug Name
AMG 890
Synonyms Olpasiran
Indication
Disease Entry ICD 11 Status REF
Cardiac fibrosis DB98.8 Phase 2 [1]
Drug Type
Small interfering RNA
Sequence
>Subunit 1
UCGUAUAACAAUAAGGGGCUG
>Subunit 2
CAGCCCCUUAUUGUUAUACGA
Cross-matching ID
TTD ID
D81AQG

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Apolipoprotein A messenger RNA (LPA mRNA) TTU9LGY APOA_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04270760) Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction - DOSE Finding Study. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Amgen.