Details of the Drug

General Information of Drug (ID: DM3JBLK)

Drug Name
PIK-93
Synonyms PIK93; PIK 93
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 389.9
Logarithm of the Partition Coefficient (xlogp) 1.4
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C14H16ClN3O4S2
IUPAC Name
N-[5-[4-chloro-3-(2-hydroxyethylsulfamoyl)phenyl]-4-methyl-1,3-thiazol-2-yl]acetamide
Canonical SMILES
CC1=C(SC(=N1)NC(=O)C)C2=CC(=C(C=C2)Cl)S(=O)(=O)NCCO
InChI
InChI=1S/C14H16ClN3O4S2/c1-8-13(23-14(17-8)18-9(2)20)10-3-4-11(15)12(7-10)24(21,22)16-5-6-19/h3-4,7,16,19H,5-6H2,1-2H3,(H,17,18,20)
InChIKey
JFVNFXCESCXMBC-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
6852167
CAS Number
593960-11-3
UNII
QS3XFL5JRX
DrugBank ID
DB06836
TTD ID
D0S5YV

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphatidylinositol-4-kinase beta (PI4KB) TTNPL3B PI4KB_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 2.3387 10.9387 -0.7562 38.3346
EW-7 GDSC1 -1.803 2.3 -1.9385 70.1378
ES5 GDSC1 -1.1854 5.897 -2.1819 60.2602
EW-18 GDSC1 -0.9621 6.0575 -1.997 58.8304
ES7 GDSC1 -0.6471 5.2798 -1.3898 57.582
TC-71 GDSC1 -0.4017 2.7713 -0.5073 57.9408
EW-16 GDSC1 0.1452 6.8707 -1.1182 51.2675
EW-3 GDSC1 0.3147 8.8563 -1.7787 50.0426
EW-1 GDSC1 0.4101 6.1931 -0.5722 49.2932
EW-13 GDSC1 0.5799 9.6469 -1.8631 48.5493
CADO-ES1 GDSC1 0.9851 6.0012 0.1154 44.1809
H-EMC-SS GDSC1 0.9944 4.9601 0.4981 43.2745
ES1 GDSC1 1.3226 8.0789 -0.4053 42.8877
MHH-ES-1 GDSC1; CTRP2 1.4538 6.2674 0.9719 32.1514
ES4 GDSC1 1.4767 10.1083 -1.1856 43.2643
EW-11 GDSC1 1.5081 9.1915 -0.7262 42.3913
ES8 GDSC1 1.5257 10.2834 -1.2204 43.0669
SK-ES-1 GDSC1; CTRP2 1.7351 5.7951 1.4072 29.8121
G-292 clone A141B1 GDSC1; CTRP2 2.0398 6.8417 1.433 28.7461
ES6 GDSC1 2.233 9.3283 -0.0808 37.1074
SK-N-MC CTRP2 2.4042 5.0904 2.2856 24.6554
MG-63 GDSC1; CTRP2 2.4648 6.53 1.9952 25.4856
SK-PN-DW GDSC1 3.0101 7.52 1.5312 26.3032
NOS-1 [Human HNSCC] GDSC1 3.0975 9.1719 0.8138 29.588
Hs 888.T CTRP2 3.2924 8.8241 2.0008 23.0538
SaOS-2 GDSC1; CTRP2 3.3895 5.2423 3.3201 17.9231
A-673 GDSC1; CTRP2 3.6989 7.0689 3.1466 17.6278
SW1353 CTRP2 3.7982 9.5116 2.2083 20.9306
CAL-78 GDSC1; CTRP2 4.117 8.6296 2.9299 17.3352
TC71 CTRP2 4.1642 6.2979 3.9181 13.3978
HuO9 GDSC1 4.3406 9.3297 1.8336 18.7387
CHSA8926 GDSC1 4.4652 19.9532 -3.3746 36.0564
HuO-3N1 GDSC1 4.5555 10.5862 1.3822 20.6852
SJSA-1 GDSC1; CTRP2 4.9461 11.3039 2.4513 17.2091
CHSA0108 GDSC1 5.2678 11.5332 1.4711 17.7679
EW-24 GDSC1 5.631 7.0539 3.8315 1.0068
NY GDSC1 6.0077 10.6755 2.4163 9.6313
HOS GDSC1; CTRP2 6.0322 11.3947 3.3591 11.276
CHSA0011 GDSC1 6.0371 11.2667 2.154 11.2954
Hs 822.T CTRP2 6.2883 8.3667 5.0798 3.6075
U2OS GDSC1 6.737 10.6625 2.8662 5.0742
CAL-72 GDSC1 7.0061 8.4175 3.8718 0.1221
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 206 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 2.7407 5.729 2.5199 22.7734
JM1 GDSC1; CTRP2 1.9081 5.2093 1.7278 28.168
SU-DHL-16 GDSC1 -3.6312 -1.6389 -3.6314 91.8486
CCRF-CEM GDSC1 -3.5346 -0.0499 -3.5568 85.4811
CESS GDSC1 -3.271 0.37 -3.3046 83.1532
HAL-01 GDSC1 -2.831 3.5004 -3.2763 72.2419
P30/OHK GDSC1 -2.5128 1.0923 -2.5629 77.55
MLMA GDSC1 -2.4993 1.7549 -2.6103 75.4565
SU-DHL-5 GDSC1 -2.4067 0.738 -2.4325 78.1057
NU-DUL-1 GDSC1; CTRP2 -2.2048 -0.6266 -2.2048 54.9568
Karpas-45 GDSC1 -2.0979 2.0505 -2.2199 72.5315
SU-DHL-6 GDSC1; CTRP2 -1.7888 1.5718 -1.807 52.1536
NKM-1 GDSC1 -1.5285 3.9953 -1.9766 64.9202
PL-21 GDSC1 -1.5142 4.7214 -2.1606 63.6389
VL51 GDSC1 -1.5087 5.2302 -2.3105 62.8569
KOPN-8 GDSC1 -1.2667 3.3172 -1.5351 64.4524
OCI-Ly19 GDSC1; CTRP2 -1.2516 4.2112 -1.5028 48.7369
HH [Human lymphoma] GDSC1 -1.25 8.5355 -3.2657 58.2051
MOLP-8 GDSC1; CTRP2 -1.2398 4.8122 -1.6057 48.7096
ML-2 GDSC1 -1.2054 4.1484 -1.6637 62.6698
ALL-PO GDSC1 -1.2038 2.1904 -1.2879 66.0589
MY-M12 GDSC1 -1.1563 7.537 -2.7627 58.5407
QIMR-WIL GDSC1 -1.1486 5.0376 -1.8579 61.0713
H9 GDSC1 -1.089 3.712 -1.4285 62.554
LC4-1 GDSC1 -0.9674 6.5466 -2.1808 58.4081
Loucy GDSC1 -0.9287 3.3218 -1.1694 61.9546
EB2 GDSC1 -0.8705 3.417 -1.1258 61.3609
SU-DHL-10 GDSC1; CTRP2 -0.8346 0.4672 -0.8346 45.829
SIG-M5 GDSC1; CTRP2 -0.7967 1.1202 -0.7974 45.5784
MHH-PREB-1 GDSC1 -0.7698 2.8266 -0.9096 61.3409
BL-70 CTRP2 -0.7656 2.3946 -0.7906 45.4208
697 GDSC1 -0.7373 6.4349 -1.8924 57.1854
RPMI-8866 GDSC1 -0.6246 4.7856 -1.2098 57.8836
OCI-AML-2 GDSC1; CTRP2 -0.6186 3.8601 -0.7681 44.6725
KMS-26 CTRP2 -0.5336 1.7729 -0.5376 43.8344
KE-37 GDSC1; CTRP2 -0.5312 3.7756 -0.6635 44.0804
LP-1 GDSC1; CTRP2 -0.4799 4.1187 -0.6574 43.8299
Ri-1 CTRP2 -0.408 5.2421 -0.7956 43.723
NALM-6 GDSC1; CTRP2 -0.3877 2.9576 -0.4316 42.9629
HC-1 GDSC1 -0.3825 12.052 -3.9278 52.9853
ROS-50 GDSC1 -0.2469 10.158 -2.9296 52.8334
GR-ST GDSC1 -0.1981 5.4945 -0.9745 54.2046
Pfeiffer CTRP2 -0.1406 3.6099 -0.2294 41.4406
BL-41 GDSC1 -0.1395 2.3606 -0.1837 55.4264
MOLM-13 GDSC1; CTRP2 -0.0992 4.3691 -0.2884 41.4022
JSC-1 GDSC1 -0.0764 6.4824 -1.2025 52.9102
RPMI-6666 GDSC1; CTRP2 0.0602 5.8158 -0.4253 41.012
NOMO-1 GDSC1; CTRP2 0.0744 5.5551 -0.344 40.7877
EoL-1 GDSC1; CTRP2 0.1285 2.8063 0.1096 39.4713
KMS-34 CTRP2 0.1521 2.0369 0.1503 39.2613
NB4 GDSC1; CTRP2 0.1686 0.9058 0.1686 39.1453
OCI-AML-5 GDSC1; CTRP2 0.2105 5.1466 -0.1016 39.6921
YT GDSC1 0.2217 5.024 -0.3624 50.906
HuT 78 CTRP2 0.3331 5.3593 -0.0157 38.9962
MC116 GDSC1; CTRP2 0.4393 2.0152 0.4387 37.344
NCI-H929 CTRP2 0.4406 2.8656 0.4269 37.3777
Farage GDSC1 0.5288 3.8297 0.3057 47.7521
TUR GDSC1 0.5374 4.7223 0.0759 47.8949
SU-DHL-4 GDSC1; CTRP2 0.6101 3.5778 0.5626 36.3564
MOLT-16 GDSC1; CTRP2 0.6185 4.3532 0.4843 36.564
WSU-DLCL2 GDSC1; CTRP2 0.6549 2.9813 0.6419 35.9483
Ramos.2G6.4C10 GDSC1 0.6748 3.6124 0.5106 46.0151
OCI-Ly3 CTRP2 0.6766 12.9003 -2.475 41.6953
ARH-77 GDSC1 0.682 8.3501 -1.1796 47.6715
P32/ISH GDSC1 0.7112 2.9777 0.6508 45.3354
KMS-21-BM CTRP2 0.7297 3.4651 0.6953 35.5192
Mono-Mac-1 CTRP2 0.8335 13.0085 -2.3645 41.07
OPM-2 GDSC1; CTRP2 0.8572 3.7915 0.8033 34.7335
BC-3 GDSC1 0.8653 4.155 0.5939 44.1015
HT GDSC1; CTRP2 0.8701 4.269 0.7647 34.8113
SU-DHL-8 GDSC1; CTRP2 0.9172 7.2467 0.0799 36.5377
ATN-1 GDSC1 0.9412 7.0624 -0.3582 45.247
Namalwa GDSC1 0.9495 3.1997 0.8762 42.4829
A4/Fukuda GDSC1; CTRP2 0.9818 5.6226 0.6286 34.8272
Karpas-422 GDSC1; CTRP2 1.0298 6.8374 0.3364 35.4721
RS4;11 GDSC1; CTRP2 1.037 7.1858 0.2302 35.7251
RPMI-8402 GDSC1; CTRP2 1.0468 3.363 1.0286 33.3549
MV4-11 GDSC1; CTRP2 1.0778 3.5408 1.0514 33.1758
MOLM-16 CTRP2 1.094 4.2958 0.9995 33.2904
Hs 611.T CTRP2 1.0963 5.4815 0.787 33.9493
Mono-Mac-6 GDSC1; CTRP2 1.1102 13.7896 -2.4414 40.3132
Kasumi-2 CTRP2 1.1495 6.3057 0.6288 34.2323
Daudi GDSC1; CTRP2 1.1892 5.3494 0.9181 33.2225
PL21 CTRP2 1.2156 6.1188 0.7541 33.6323
BE-13 GDSC1 1.2528 5.6604 0.531 41.2194
ST486 GDSC1; CTRP2 1.3601 3.7817 1.3291 31.3108
Kasumi-1 CTRP2 1.3615 4.3895 1.2722 31.4953
JJN-3 GDSC1; CTRP2 1.3852 5.7314 1.0416 32.1642
CA46 GDSC1 1.3927 5.5172 0.7343 39.5651
KMS-11 GDSC1; CTRP2 1.4056 6.3605 0.8922 32.5614
GA-10 CTRP2 1.4082 4.0519 1.3582 31.0536
BALL-1 GDSC1 1.421 7.0801 0.1337 41.1377
KMS-20 CTRP2 1.4381 5.1314 1.234 31.3653
CTV-1 GDSC1 1.4456 6.0564 0.5838 39.7007
OCI-AML-3 GDSC1; CTRP2 1.449 4.3018 1.3757 30.8598
HL-60 GDSC1; CTRP2 1.4558 5.3192 1.2144 31.3703
KMS-18 CTRP2 1.471 5.3794 1.2179 31.3079
CML-T1 CTRP2 1.5056 3.8522 1.4755 30.3388
Sc-1 GDSC1 1.5092 6.7685 0.3581 39.9669
VAL GDSC1 1.5194 6.2522 0.5831 39.2051
P12-Ichikawa GDSC1; CTRP2 1.5625 4.8238 1.4243 30.3219
U-698-M GDSC1 1.5691 6.1209 0.6887 38.5138
EJM GDSC1; CTRP2 1.5698 7.8564 0.5693 32.9593
SUP-T1 GDSC1; CTRP2 1.6359 6.2073 1.1879 30.8579
THP-1 GDSC1; CTRP2 1.661 5.6866 1.3534 30.2335
WSU-NHL GDSC1 1.6645 15.0649 -3.3982 44.705
SUP-HD1 GDSC1; CTRP2 1.7272 6.4707 1.2099 30.4868
EM-2 GDSC1; CTRP2 1.7848 4.2838 1.7323 28.5542
DB GDSC1; CTRP2 1.7897 5.2931 1.5825 29.0456
HuNS1 CTRP2 1.7984 6.6394 1.2354 30.1718
EB1 CTRP2 1.7994 7.211 1.0478 30.7684
WIL2 NS GDSC1 1.8001 8.0846 0.0745 38.9975
SEM CTRP2 1.8369 4.6264 1.7478 28.3314
KMS-12-BM GDSC1; CTRP2 1.8382 4.7597 1.7303 28.3862
Jiyoye GDSC1 1.8723 9.4765 -0.5013 40.0223
MOTN-1 CTRP2 1.877 5.9129 1.5316 28.9352
KMOE-2 GDSC1 1.8823 6.2774 0.9538 35.4603
Mino CTRP2 1.8827 3.082 1.8821 27.7278
A3/Kawakami GDSC1 1.9011 7.3916 0.4898 37.1287
BV-173 GDSC1; CTRP2 1.9191 5.9207 1.5755 28.6508
RCH-ACV CTRP2 1.9437 5.57 1.6892 28.185
PF-382 GDSC1; CTRP2 1.9618 5.3226 1.7632 27.8739
AML-193 CTRP2 1.9948 5.5397 1.7518 27.8069
ALL-SIL GDSC1; CTRP2 2.0187 5.2844 1.8327 27.4526
L-363 GDSC1; CTRP2 2.0298 5.4583 1.8082 27.5012
MOLT-13 GDSC1; CTRP2 2.0381 6.3464 1.5862 28.2348
SUP-T11 CTRP2 2.0455 5.2331 1.872 27.2314
MOLT-4 GDSC1 2.0511 6.0935 1.2071 33.2602
AMO1 GDSC1; CTRP2 2.1165 6.2031 1.7134 27.5514
MM1.S CTRP2 2.1278 4.3013 2.0908 26.2171
KMS-27 CTRP2 2.1385 5.1556 1.9874 26.536
GDM-1 GDSC1; CTRP2 2.1827 5.2886 2.0098 26.3172
Ki-JK CTRP2 2.2151 4.1875 2.1903 25.5944
KG-1 GDSC1 2.2216 7.9853 0.5406 35.1265
DND-41 GDSC1; CTRP2 2.2393 6.9271 1.6211 27.4839
SK-MM-2 GDSC1; CTRP2 2.2516 7.9965 1.2464 28.6995
SKM-1 CTRP2 2.2993 4.539 2.2489 25.1203
RPMI-8226 GDSC1; CTRP2 2.3192 5.1912 2.1761 25.306
U-937 CTRP2 2.3321 3.0667 2.3321 24.7316
JeKo-1 CTRP2 2.4201 5.8977 2.1282 25.1546
MHH-CALL-4 CTRP2 2.462 6.4642 2.0126 25.4327
Jurkat CTRP2 2.4629 4.6485 2.41 24.0389
Peer CTRP2 2.4954 4.256 2.4765 23.7072
TALL-1 [Human adult T-ALL] CTRP2 2.5488 6.3608 2.1387 24.7197
KE-97 CTRP2 2.6035 6.0731 2.2814 24.0441
JVM-3 GDSC1; CTRP2 2.6327 9.0195 0.4505 22.0294
EHEB CTRP2 2.6423 7.2384 1.9486 25.1125
L-540 GDSC1; CTRP2 2.649 6.2029 2.2944 23.8585
RL GDSC1; CTRP2 2.6771 4.2576 2.6639 22.4778
TK [Human B-cell lymphoma] GDSC1 2.7564 10.5005 -0.1526 34.8188
NU-DHL-1 CTRP2 2.76 6.2815 2.3926 23.1679
SUP-B15 GDSC1; CTRP2 2.8735 8.0281 1.8949 24.6222
JVM-2 GDSC1; CTRP2 2.9105 10.1354 1.031 27.4383
SR GDSC1; CTRP2 2.9731 6.1113 2.6741 21.507
F-36P CTRP2 3.033 4.9962 2.9736 20.2638
KMS-28BM CTRP2 3.0381 6.1288 2.7401 21.0717
M-07e CTRP2 3.0997 8.1566 2.0816 23.3007
BC-1 GDSC1 3.1529 7.3944 1.7285 24.4307
L-1236 GDSC1; CTRP2 3.1844 9.1717 1.7382 24.294
SET-2 CTRP2 3.2091 6.2301 2.8975 19.9846
KCL-22 GDSC1; CTRP2 3.3651 6.7587 2.8983 19.5185
LAMA-84 GDSC1; CTRP2 3.3837 6.2681 3.0767 18.8076
DoHH2 CTRP2 3.389 4.9304 3.3578 17.7957
HDLM-2 GDSC1; CTRP2 3.4031 6.967 2.866 19.5279
KO52 CTRP2 3.4116 7.5312 2.6625 20.2658
SUP-M2 GDSC1 3.444 4.635 3.2632 12.1984
Ku812 GDSC1; CTRP2 3.4479 5.9172 3.2445 18.0064
MOLP-2 CTRP2 3.4784 9.0354 2.0993 22.1852
JURL-MK1 GDSC1; CTRP2 3.481 6.8044 3.0079 18.7737
HEL 92.1.7 CTRP2 3.5193 5.7655 3.3595 17.3754
MN-60 GDSC1 3.5244 9.0411 1.2687 25.3995
MEG-01 GDSC1 3.5611 4.8952 3.2868 11.4169
SU-DHL-1 GDSC1; CTRP2 3.577 4.8492 3.5609 16.4923
Hs 445 GDSC1 3.5791 8.1384 1.7641 22.2607
L-428 GDSC1; CTRP2 3.7778 6.8087 3.3268 16.7241
CMK CTRP2 3.7806 5.7286 3.6524 15.5241
U266B1 GDSC1; CTRP2 3.7908 6.5239 3.4392 16.2672
HEL GDSC1; CTRP2 3.8108 5.5287 3.7258 15.1715
RC-K8 GDSC1 3.8653 7.513 2.3316 17.2135
MOLM-6 CTRP2 3.8753 7.0429 3.3454 16.3762
DG-75 GDSC1 3.8886 7.404 2.4064 16.5777
KM-H2 GDSC1; CTRP2 3.9617 7.7409 3.1578 16.8569
Karpas-299 GDSC1; CTRP2 3.9909 6.9147 3.5174 15.397
Granta-519 GDSC1; CTRP2 4.0768 8.9332 2.7518 18.1338
DEL GDSC1; CTRP2 4.1573 5.79 4.0485 12.9478
CTB-1 GDSC1 4.1996 13.8885 -0.5637 30.4378
SCC-3 GDSC1 4.2812 5.0523 3.9223 3.3029
P31/FUJ GDSC1; CTRP2 4.3699 5.1619 4.363 11.1787
KY821 GDSC1 4.3728 5.4244 3.8125 3.8372
MHH-CALL-3 CTRP2 4.4498 10.6759 2.2949 18.9693
NCO2 CTRP2 4.4824 6.2739 4.2719 11.1525
K-562 GDSC1; CTRP2 4.4867 7.7022 3.719 13.2655
HPB-ALL CTRP2 4.5262 8.2019 3.5364 13.8891
TF-1 CTRP2 5.0249 8.3275 3.9719 10.901
KYO-1 CTRP2 5.3177 7.6934 4.5568 7.8127
ME1 GDSC1 5.4201 14.1017 0.3144 23.139
HD-MY-Z CTRP2 5.5368 9.696 3.78 10.5393
Ci-1 CTRP2 5.5927 7.7835 4.7747 6.2782
OCI-M1 GDSC1; CTRP2 5.7605 6.3095 5.6366 2.3544
REC-1 CTRP2 5.9281 9.5058 4.2158 7.9122
KMM-1 CTRP2 6.1512 12.527 2.8917 12.9419
P3HR-1 CTRP2 6.6024 12.5603 3.239 10.7003
ME1 CTRP2 6.8081 9.9142 4.7031 4.3233
Raji GDSC1; CTRP2 7.8322 14.0572 3.4124 8.0016
Reh GDSC1; CTRP2 8.1112 9.4231 5.6213 0.1229
Karpas-620 GDSC1; CTRP2 8.2277 9.7182 5.5607 0.1773
⏷ Show the Full List of 206 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 3.71 7.819 2.8617 18.6815
TE8 CTRP2 3.9733 8.2969 2.9314 17.7045
KYSE-270 GDSC1 2.3053 4.921 1.9326 27.6212
TE-15 GDSC1 2.8727 7.8091 1.2608 28.4784
TE-5 GDSC1; CTRP2 2.9509 5.659 2.7653 21.2504
KYSE-410 GDSC1; CTRP2 3.1115 7.752 2.2568 22.6264
T.T GDSC1 3.4447 5.6385 2.8409 15.2907
OE21 GDSC1; CTRP2 3.4571 6.4628 3.0964 18.5164
OE33 GDSC1; CTRP2 3.5025 8.5524 2.3352 21.2439
TE-14 CTRP2 3.7031 6.7974 3.2503 17.2259
TE-6 GDSC1; CTRP2 3.7476 7.4523 3.0503 17.8571
KYSE-70 GDSC1; CTRP2 3.9968 7.3477 3.3559 15.9971
KYSE-180 GDSC1; CTRP2 4.0615 8.9115 2.7463 18.1943
KYSE-140 GDSC1; CTRP2 4.1032 8.7685 2.8532 17.6705
TE-10 GDSC1; CTRP2 4.2047 7.5082 3.5091 14.8375
KYSE-510 GDSC1; CTRP2 4.2839 6.2132 4.0745 12.4676
EC-GI-10 GDSC1; CTRP2 4.303 8.5685 3.1452 16.0111
TE-11 GDSC1; CTRP2 4.3477 6.5294 4.0408 12.4047
KYSE-520 GDSC1; CTRP2 4.4801 8.287 3.4513 14.3452
TE-9 GDSC1; CTRP2 4.7462 5.9312 4.6569 8.9585
TE-4 GDSC1; CTRP2 4.7505 7.0239 4.282 10.3561
KYSE-30 CTRP2 4.954 5.9377 4.8817 7.5149
TE-8 GDSC1 4.98 12.6512 0.6922 22.8206
TE-1 GDSC1; CTRP2 5.6398 8.0001 4.7118 6.4345
OE19 GDSC1; CTRP2 5.68 6.2596 5.5726 2.8218
COLO 680N GDSC1; CTRP2 5.7017 8.3216 4.6089 6.7296
KYSE-150 GDSC1; CTRP2 6.0272 11.127 3.4888 10.751
KYSE-450 GDSC1; CTRP2 7.8093 15.988 2.4558 11.7281
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.5864 9.2596 3.1041 15.4702
MZ-PC-1 GDSC1 0.1411 6.7809 -1.087 51.31
HuP-T4 GDSC1; CTRP2 1.2216 7.4613 0.3359 34.7932
Panc 03.27 GDSC1; CTRP2 2.9422 9.1374 1.5037 25.7905
BxPC-3 GDSC1; CTRP2 3.138 8.4278 2.0094 23.4541
SNU-213 CTRP2 3.3463 8.8896 2.0279 22.807
Panc 08.13 GDSC1; CTRP2 3.4992 7.0075 2.9549 18.9191
PK-59 CTRP2 4.0265 6.6043 3.6674 14.7309
Panc 05.04 CTRP2 4.0785 7.4318 3.4081 15.5716
HPAC GDSC1; CTRP2 4.1058 7.123 3.5606 14.9098
KP-2 GDSC1; CTRP2 4.1627 8.7477 2.9226 17.2459
HPAF-II GDSC1 4.2301 9.0808 1.8656 18.9504
Panc 10.05 GDSC1 4.3587 7.4198 2.8036 11.788
PK-45H CTRP2 4.4296 12.1231 1.5729 21.66
PaTu 8988s CTRP2 4.4509 8.2553 3.4362 14.4793
L3.3 CTRP2 4.5756 7.2933 3.9866 11.9788
SW1990 GDSC1; CTRP2 4.675 8.4442 3.5738 13.3661
KP-4 GDSC1; CTRP2 4.6768 7.6912 3.9184 11.9818
PL4 GDSC1 4.7222 6.8637 3.3672 6.1957
Hs 766T GDSC1; CTRP2 4.7509 8.1405 3.7896 12.3092
TCC-Pan2 CTRP2 4.7706 8.6546 3.5694 13.1494
DAN-G GDSC1; CTRP2 4.8868 7.4053 4.2595 10.0841
Capan-1 GDSC1 5.0278 8.1668 2.9513 8.4653
KP-3 GDSC1; CTRP2 5.0665 11.2873 2.5692 16.4793
AsPC-1 GDSC1; CTRP2 5.1746 11.3491 2.6364 15.9757
MIA PaCa-2 GDSC1; CTRP2 5.2213 7.99 4.3224 9.0006
Panc 04.03 GDSC1; CTRP2 5.2993 7.3013 4.7227 7.1835
Panc 02.03 GDSC1; CTRP2 5.3052 10.2547 3.2954 13.039
SU.86.86 GDSC1; CTRP2 5.4668 8.1903 4.4589 7.8696
YAPC GDSC1; CTRP2 5.6487 10.4531 3.5022 11.4568
SUIT-2 GDSC1; CTRP2 5.7492 9.9176 3.8566 9.7766
CFPAC-1 GDSC1; CTRP2 5.7977 9.6289 4.0426 8.9005
QGP-1 GDSC1; CTRP2 5.9362 12.7748 2.5886 14.5643
PaTu 8902 GDSC1; CTRP2 5.984 8.2496 4.8911 4.9654
PaTu 8988t GDSC1; CTRP2 5.9952 9.8337 4.1086 8.2301
HuP-T3 GDSC1; CTRP2 6.0031 14.4674 1.7984 17.4053
Capan-2 GDSC1; CTRP2 6.241 10.0433 4.2063 7.3531
PSN1 GDSC1; CTRP2 8.0363 17.5262 1.8671 13.5116
SNU-410 CTRP2 8.1494 10.2736 5.321 0.6915
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.4095 12.3415 1.6954 14.1083
COLO 792 GDSC1; CTRP2 1.1439 5.8306 0.7532 33.8848
WM35 GDSC1 1.283 7.5403 -0.208 42.7657
CHL-1 GDSC1 1.5434 5.1507 1.0288 37.3628
WM88 CTRP2 2.5205 5.6177 2.3062 24.215
Hs 852.T CTRP2 2.6576 6.1287 2.325 23.7227
A-431 GDSC1 2.7299 5.763 2.0544 24.4678
RPMI-7951 GDSC1; CTRP2 2.7623 6.2486 2.4047 23.1175
WM115 GDSC1; CTRP2 2.7661 7.7914 1.8741 25.0096
MZ-MEL-2 GDSC1 2.8455 6.5583 1.82 25.3825
Hs 294T CTRP2 2.8551 6.0837 2.553 22.3021
CP50-MEL-B GDSC1 2.8978 6.4557 1.9192 24.4822
Hs 895.T CTRP2 3.0116 9.5119 1.4115 25.9062
Mel Ho GDSC1; CTRP2 3.0524 7.2762 2.3759 22.3593
MZ-MEL-7 GDSC1 3.1542 9.0165 0.9423 28.7263
WM278 GDSC1 3.2075 9.5095 0.7495 29.3773
A101D GDSC1; CTRP2 3.3478 6.3135 3.0238 19.1079
G-361 GDSC1; CTRP2 3.3851 6.5606 2.9864 19.1342
Mel JuSo GDSC1; CTRP2 3.41 9.5073 1.8192 23.3865
A-388 GDSC1 3.4521 5.4384 2.9389 14.5251
Hs 944.T CTRP2 3.564 8.6078 2.3747 20.9288
M14 GDSC1 3.635 12.5908 -0.3981 31.9536
IGR-1 GDSC1; CTRP2 3.6577 7.8735 2.7843 19.1202
SK-MEL-24 GDSC1 3.7483 10.3727 0.8062 26.7972
IST-MEL1 GDSC1 3.8757 10.6403 0.7836 26.39
WM793 GDSC1; CTRP2 3.8779 8.4994 2.7446 18.6798
WM266-4 CTRP2 4.0572 7.9578 3.165 16.573
COLO 679 GDSC1 4.0819 8.5907 1.9843 18.7459
SK-MEL-3 GDSC1; CTRP2 4.0884 6.5876 3.7401 14.2795
LOX-IMVI GDSC1; CTRP2 4.2271 7.3496 3.5981 14.4314
SK-MEL-2 GDSC1; CTRP2 4.2776 6.0584 4.1124 12.3491
451Lu GDSC1 4.2902 7.2486 2.8321 11.82
CJM [Human melanoma] CTRP2 4.3151 7.2396 3.7357 13.6587
G-mel GDSC1 4.3277 8.2508 2.3623 15.1835
RVH-421 GDSC1; CTRP2 4.331 8.9813 2.9836 16.5795
LB2518-MEL GDSC1 4.3446 5.5817 3.7108 4.7381
LB373-MEL-D GDSC1 4.49 10.8973 1.1732 22.0812
Hs 940.T GDSC1; CTRP2 4.5483 6.5216 4.2603 11.0032
SK-MEL-5 GDSC1; CTRP2 4.6197 9.4209 3.0597 15.5674
HMV-II GDSC1 4.63 10.0027 1.734 18.3162
IGR-39 CTRP2 4.6528 10.5669 2.5396 17.5441
IPC-298 GDSC1; CTRP2 4.7576 9.4458 3.1804 14.7532
DJM-1 GDSC1 4.7979 7.7137 3.0045 8.7606
GAK GDSC1 4.7983 9.1876 2.2737 14.1525
WM983B CTRP2 4.8996 10.7014 2.7044 16.3251
MDA-MB-435S CTRP2 4.9304 9.754 3.1954 14.2882
WM1799 CTRP2 4.9433 8.0518 4.0216 10.897
MeWo GDSC1; CTRP2 4.9531 7.8018 4.1472 10.3652
SH-4 GDSC1 4.9698 17.4824 -1.7265 31.3087
COLO 783 GDSC1 4.9893 8.6715 2.6751 10.6432
SK-MEL-1 GDSC1; CTRP2 5.0595 8.0661 4.1291 10.1774
MMAc-SF GDSC1 5.0783 10.0147 2.0787 14.5702
A-375 GDSC1; CTRP2 5.1739 9.3127 3.6382 11.9229
A2058 GDSC1; CTRP2 5.2671 6.4306 5.0664 5.9098
CP66-MEL GDSC1 5.3102 8.0459 3.2052 5.7942
HT-144 GDSC1; CTRP2 5.5134 11.9897 2.6184 15.3156
COLO 741 CTRP2 5.7831 21.1625 -1.7334 27.8502
UACC-257 GDSC1; CTRP2 5.795 11.6954 3.0085 13.1774
Hs 938.T GDSC1 5.8345 9.7427 2.7447 7.8039
WT2-iPS GDSC1; CTRP2 5.9133 8.1505 4.8802 5.1527
COLO 800 GDSC1; CTRP2 5.9335 13.8672 2.0402 16.661
SK-MEL-30 GDSC1; CTRP2 5.9801 11.7837 3.121 12.3513
Malme-3M CTRP2 6.0106 16.5886 0.7441 20.946
IGR-37 GDSC1; CTRP2 6.0766 15.2052 1.4908 18.3474
COLO 829 GDSC1; CTRP2 6.1482 10.7633 3.7708 9.3476
HMCB CTRP2 6.2255 10.0324 4.1992 7.4117
UACC-62 GDSC1; CTRP2 6.3538 11.4959 3.572 9.7879
WM1552C GDSC1 6.4928 8.5037 3.6458 1.0204
VMRC-MELG GDSC1 6.55 8.4765 3.6803 0.831
Hs 688(A).T CTRP2 6.5702 11.3816 3.8003 8.4533
Hs 839.T CTRP2 6.6997 15.5035 1.8493 15.8791
Hs 936.T CTRP2 6.9305 10.9682 4.2763 5.8843
K029AX CTRP2 7.0283 16.8902 1.418 16.7928
Hs 934.T CTRP2 7.0731 11.7157 4.0137 6.7364
SK-MEL-31 CTRP2 7.4205 12.2242 4.0126 6.2135
SK-MEL-28 GDSC1; CTRP2 8.1086 14.9211 3.1862 8.4821
EquiPSC Line K2 GDSC1 4.3466 7.5902 2.7083 12.5572
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC1 -1.7568 3.663 -2.1443 66.8557
OACM5.1 C GDSC1 -0.9076 5.2026 -1.6479 59.379
KYAE-1 GDSC1 0.3571 4.6851 -0.1094 49.6624
FLO-1 GDSC1 2.2844 9.6203 -0.171 37.1072
SK-GT-4 GDSC1 3.076 8.6972 1.0254 28.688
ESO-26 GDSC1 3.5138 6.9486 2.2865 19.0453
ESO-51 GDSC1 3.9508 8.0471 2.1417 18.2012
KYSE-50 GDSC1 4.0853 6.2785 3.1401 10.2097
KYSE-220 GDSC1 4.7149 11.1526 1.2283 20.9817
TE-12 GDSC1 5.5367 11.9867 1.4488 17.066
HCE-4 GDSC1 6.8063 8.499 3.7728 0.3754
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 2.8204 8.2683 1.742 25.3167
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-ME-N GDSC1 1.0565 9.674 -1.3981 45.6953
KP-N-YS GDSC1 1.4891 7.7335 -0.082 41.2263
SJNB-14 GDSC1 1.6387 4.5746 1.321 35.3344
NB(TU)1 GDSC1 2.2937 6.6124 1.2361 31.6913
SJNB-13 GDSC1 2.303 5.2998 1.7913 28.5216
IMR-5 GDSC1 2.5823 7.4591 1.1421 30.5764
SK-N-MC-IXC GDSC1 2.6156 4.652 2.3602 23.0221
IMR-32 CTRP2 2.8202 5.5063 2.6567 22.0422
TGW GDSC1 3.1263 6.1472 2.2893 20.8398
NH-12 GDSC1 3.1772 8.8785 1.0312 28.1881
SK-N-SH GDSC1; CTRP2 3.2985 10.6131 1.203 25.8043
Kelly GDSC1; CTRP2 3.3127 5.8997 3.1015 18.9337
MHH-NB-11 GDSC1; CTRP2 3.3778 6.8335 2.8861 19.5264
NB1 GDSC1; CTRP2 3.5536 6.4043 3.22 17.776
SiMa GDSC1; CTRP2 3.6109 7.0735 3.0506 18.2401
SJNB-5 GDSC1 3.6589 9.4465 1.1881 25.2545
NH-6 CTRP2 3.7309 8.7542 2.4818 20.0762
SK-N-AS GDSC1 3.7392 7.5482 2.2007 18.6679
GOTO GDSC1 3.8786 5.9512 3.1136 11.2629
SJNB-10 GDSC1 3.9474 5.19 3.5466 7.6211
KP-N-SI9s CTRP2 3.9553 8.6848 2.7412 18.4894
SK-N-BE(2) CTRP2 3.9759 7.7037 3.1882 16.701
SJNB-7 GDSC1 4.1227 6.2347 3.1948 9.6346
CHP-126 GDSC1; CTRP2 4.2289 9.7261 2.535 18.5896
NB69 GDSC1 4.2471 6.3104 3.2647 8.6108
SJNB-12 GDSC1 4.2703 9.06 1.9097 18.5103
CHP-134 GDSC1 4.2976 9.3797 1.7727 19.2882
SK-N-DZ GDSC1; CTRP2 4.3882 6.0453 4.2367 11.5637
LA-N-6 GDSC1 4.392 10.3665 1.3579 21.4199
SJNB-6 GDSC1 4.5116 7.0896 3.0928 9.0148
KP-N-YN GDSC1; CTRP2 4.9086 6.788 4.5448 8.9068
SK-N-BE(2)-M17 GDSC1 5.262 8.547 2.9323 7.9394
SJNB-17 GDSC1 5.2816 11.1703 1.661 16.5936
SK-N-FI GDSC1 5.6314 7.5875 3.6081 2.3007
CHP-212 GDSC1 5.9055 8.0035 3.5732 2.0801
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 3.1605 6.4919 2.7644 20.6149
SNU-478 CTRP2 3.1941 6.4718 2.8074 20.3575
HuH-28 CTRP2 3.6601 7.6838 2.8647 18.807
HuCC-T1 GDSC1; CTRP2 3.8416 6.5278 3.4929 15.919
SNU-245 CTRP2 4.4503 8.8682 3.1543 15.6044
SNU-308 CTRP2 4.926 8.0809 3.991 11.0629
SNU-1196 CTRP2 5.7972 8.9438 4.3838 7.472
SNU-869 CTRP2 6.7857 30.0575 -5.3502 32.1058
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1599 GDSC1 -0.7516 4.8496 -1.3675 58.7196
OCUB-M GDSC1 0.68 5.1303 0.1005 46.6191
MDA-MB-453 GDSC1; CTRP2 1.2764 5.698 0.9313 32.8813
Hs 578T GDSC1; CTRP2 1.6463 5.6309 1.3509 30.2901
Evsa-T GDSC1 1.7167 5.6951 1.0138 36.2605
HCC1187 GDSC1 2.1905 5.2753 1.6803 29.8536
MDA-MB-361 GDSC1; CTRP2 2.2375 4.5695 2.1804 25.5547
EFM-192A GDSC1; CTRP2 2.297 5.9661 1.9759 26.0738
HCC1419 GDSC1; CTRP2 2.3054 6.862 1.7146 26.9573
EFM-19 GDSC1 2.6273 11.092 -0.5617 36.5625
HCC70 GDSC1 2.6469 5.1772 2.2055 23.9002
CAL-120 GDSC1 2.6478 7.8109 1.0416 30.723
CAL-148 GDSC1; CTRP2 2.6768 5.5196 2.498 23.0505
SK-BR-3 CTRP2 2.8565 5.9101 2.601 22.1265
ZR-75-30 GDSC1; CTRP2 2.8723 7.6115 2.0567 24.046
HCC202 GDSC1; CTRP2 3.0123 8.6627 1.7794 24.6331
ZR-75-1 CTRP2 3.0225 6.6491 2.5635 21.7595
AU565 GDSC1; CTRP2 3.0367 7.6729 2.2083 23.0185
BT-549 GDSC1; CTRP2 3.1816 8.2218 2.1408 22.853
DU4475 GDSC1; CTRP2 3.3327 6.1877 3.0447 19.0774
HMC-1-8 CTRP2 3.417 5.9923 3.1911 18.2926
CAL-85-1 GDSC1; CTRP2 3.4784 8.5309 2.3196 21.3682
BT-474 GDSC1; CTRP2 3.4941 6.922 2.9803 18.8388
BT-20 GDSC1; CTRP2 3.7306 6.2395 3.4634 16.3569
HCC2218 GDSC1; CTRP2 3.752 7.1315 3.1799 17.3517
MDA-MB-468 GDSC1; CTRP2 3.7538 6.3499 3.4549 16.3187
UACC-893 GDSC1 3.7728 10.0715 0.9776 25.8648
MDA-MB-175-VII GDSC1 3.808 6.2243 2.9145 13.0974
MDA-MB-330 GDSC1 3.8631 7.9655 2.105 18.8127
HCC38 GDSC1; CTRP2 3.9453 7.3196 3.3126 16.3055
COLO 824 GDSC1 3.9544 11.191 0.5765 27.0288
HCC1143 CTRP2 3.9923 6.9937 3.4892 15.5002
T-47D GDSC1; CTRP2 4.0072 10.8159 1.8034 21.8803
MRK-nu-1 GDSC1 4.0503 7.3022 2.5998 14.4991
MFM-223 GDSC1 4.1939 6.5544 3.0973 10.1233
YMB-1-E GDSC1 4.2845 9.7697 1.5667 20.6056
HCC1569 GDSC1 4.3191 10.1944 1.3834 21.5468
MDA-MB-415 GDSC1 4.3251 6.3222 3.3245 7.8531
MDA-MB-436 GDSC1 4.463 10.802 1.1987 22.0416
HCC1954 GDSC1 4.5873 7.477 2.9597 9.7897
CAL-51 GDSC1; CTRP2 4.7024 5.7161 4.6546 9.1037
HCC2157 GDSC1 4.7697 6.628 3.5174 4.8949
HCC1806 GDSC1 4.787 11.0584 1.333 20.1495
HCC1937 GDSC1; CTRP2 4.8626 9.6844 3.1653 14.5675
HDQ-P1 GDSC1; CTRP2 4.9945 9.166 3.5408 12.7338
UACC-812 GDSC1 4.999 7.543 3.2348 6.4023
HCC1500 GDSC1; CTRP2 5.173 9.0672 3.757 11.436
CAMA-1 GDSC1; CTRP2 5.3311 9.0518 3.9115 10.4419
MDA-MB-231 GDSC1; CTRP2 5.3942 9.2959 3.8494 10.5595
HCC1395 GDSC1; CTRP2 5.4036 9.0045 4.0014 9.9082
BT-483 GDSC1 5.4218 13.3181 0.7044 21.3512
HCC1428 GDSC1; CTRP2 5.5531 8.4979 4.3875 7.9747
MDA-MB-157 GDSC1; CTRP2 5.6329 7.3891 5.0044 5.2365
MCF-7 GDSC1; CTRP2 5.824 9.4802 4.1396 8.4409
JIMT-1 GDSC1; CTRP2 5.9336 10.1109 3.9181 9.1486
Hs 578Bst CTRP2 6.563 12.752 3.1124 11.2835
KPL-1 CTRP2 7.4003 19.6328 0.3445 19.5551
BT 416 CTRP2 0.4217 4.0253 0.3186 37.7724
BT 239 CTRP2 3.0575 7.8669 2.154 23.1571
BT 231 CTRP2 3.5514 8.6309 2.3517 21.0494
BT 139 CTRP2 3.7267 7.9991 2.804 18.8566
BT 248 CTRP2 4.0149 8.5163 2.877 17.8066
BT 112 CTRP2 4.1273 8.4998 2.9987 17.0389
BT 482 CTRP2 4.1384 9.6572 2.4785 19.034
BT 428 CTRP2 4.2731 7.5004 3.5839 14.3621
BT 245 CTRP2 4.4997 6.1728 4.3219 10.9178
BT 145 CTRP2 4.593 8.114 3.6435 13.2916
BT 286 CTRP2 4.915 9.1933 3.4521 13.2815
BT 330 CTRP2 4.9731 10.1859 3.0248 14.8793
BT147 CTRP2 4.9994 7.4509 4.3536 9.42
BT164 CTRP2 5.1379 9.631 3.4491 12.781
BT 271 CTRP2 5.1982 10.1214 3.2639 13.4035
BT 159 CTRP2 5.3163 11.9102 2.4846 16.26
BT 172 CTRP2 5.3241 6.6516 5.0375 5.8658
BT 333 CTRP2 5.4989 9.5835 3.802 10.529
BT 228 CTRP2 5.701 13.4701 2.0416 17.1307
BT 359 CTRP2 5.7708 11.2453 3.2125 12.3975
BT 187 CTRP2 5.7785 11.9153 2.8845 13.7097
BT 444 CTRP2 5.8374 10.9638 3.4102 11.4515
BT 422 CTRP2 5.8459 10.1862 3.8059 9.7923
BT 216 CTRP2 5.8692 12.7607 2.5392 14.8917
BT 224 CTRP2 5.8778 11.1244 3.3642 11.5597
BT 131 CTRP2 5.9081 10.1655 3.8693 9.4033
BT 232 CTRP2 6.1807 9.0514 4.6529 5.5909
BT 320 CTRP2 6.3161 10.9608 3.8088 8.8751
BT 179 CTRP2 6.3565 12.0011 3.322 10.8111
BT 340 CTRP2 6.5816 11.0796 3.9593 7.7739
BT 504 CTRP2 6.6377 13.3992 2.849 12.201
BT 328 CTRP2 6.7302 11.4989 3.8655 7.9068
BT 440 CTRP2 6.8469 14.3825 2.5238 13.0941
BT 498 CTRP2 7.3407 17.2371 1.4883 15.9976
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.7471 5.6511 3.6327 15.6988
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-423MG GDSC1 0.5832 8.5318 -1.3608 48.3588
D-247MG GDSC1 0.9893 8.0605 -0.7374 45.4052
D283 Med GDSC1; CTRP2 2.3199 3.4698 2.319 24.8162
YH-13 GDSC1; CTRP2 2.4155 8.8933 1.0594 28.7991
D-542MG GDSC1 2.6282 5.5725 2.028 25.1886
GaMG GDSC1; CTRP2 2.8824 7.702 2.0327 24.1027
D-566MG GDSC1 2.908 8.7733 0.8306 30.4058
AM-38 GDSC1 3.1481 4.8011 2.8842 16.4654
KINGS-1 GDSC1 3.2219 13.312 -1.1198 35.539
KS-1 [Human Krukenberg tumour] GDSC1 3.294 7.9246 1.6057 24.5139
MOG-G-CCM GDSC1 3.3121 8.8056 1.1915 26.7542
M059J GDSC1 3.3474 7.2092 2.003 21.7531
SF539 GDSC1; CTRP2 3.4481 6.9317 2.9272 19.1698
T98G GDSC1; CTRP2 3.4616 6.3612 3.1333 18.3676
Hs 683 GDSC1; CTRP2 3.5828 6.0682 3.3515 17.2092
GMS-10 CTRP2 3.655 10.5752 1.5733 23.6001
D-502MG GDSC1 3.6799 12.069 -0.0988 30.7761
42-MG-BA GDSC1; CTRP2 3.737 8.9889 2.3835 20.4325
KNS-81-FD GDSC1 3.7529 9.6323 1.1788 24.9106
PFSK-1 GDSC1 3.7706 10.5753 0.7247 27.0867
MOG-G-UVW GDSC1 3.7913 5.9905 3.0127 12.4156
GI-1 GDSC1 3.8233 12.2738 -0.0768 30.1479
Becker GDSC1; CTRP2 3.8679 8.0968 2.9093 18.0707
DK-MG GDSC1; CTRP2 3.8898 10.4848 1.8461 22.025
SF126 GDSC1; CTRP2 3.9562 8.4907 2.8284 18.1493
KNS-60 CTRP2 3.9636 7.6533 3.1962 16.7031
D-336MG GDSC1 4.0264 6.5911 2.9325 12.0577
LNZTA3WT4 GDSC1 4.0611 6.4612 3.0279 11.1796
CAS-1 GDSC1; CTRP2 4.0823 9.5325 2.4813 19.1651
Daoy GDSC1; CTRP2 4.182 8.7132 2.9577 17.0592
SF268 GDSC1; CTRP2 4.192 8.103 3.2408 15.9202
YKG-1 GDSC1 4.2021 8.5024 2.131 17.2852
SNU-201 CTRP2 4.4606 8.2969 3.4272 14.4909
M059K CTRP2 4.4708 9.2621 2.9902 16.2065
SF295 GDSC1; CTRP2 4.4929 8.5699 3.3347 14.7782
GB-1 GDSC1; CTRP2 4.4936 11.1509 2.1063 19.5753
U-118MG GDSC1; CTRP2 4.5609 9.7474 2.8471 16.5552
SNU-1105 CTRP2 4.6126 13.0947 -0.7347 15.4873
A-172 GDSC1; CTRP2 4.6355 9.158 3.1999 14.9671
LN-405 GDSC1 4.6606 9.4761 2.0213 16.3512
KG-1-C CTRP2 4.7252 10.1398 2.815 16.2916
LN-18 GDSC1; CTRP2 4.7303 6.1044 4.5934 9.2357
SW1783 GDSC1 4.7338 7.2586 3.1811 7.6018
Onda 11 GDSC1 4.7899 8.2897 2.7133 10.9921
KALS-1 GDSC1; CTRP2 4.8533 11.6135 2.2141 18.3284
NMC-G1 GDSC1; CTRP2 4.9815 9.8932 3.1755 14.2513
SK-MG-1 GDSC1 4.9956 9.9229 2.0611 14.9546
SW1088 GDSC1; CTRP2 5.002 9.9733 3.1556 14.2853
SNU-626 CTRP2 5.0034 8.8484 3.7023 12.0529
ONS-76 GDSC1; CTRP2 5.0334 7.4145 4.4044 9.1304
D-263MG GDSC1 5.0532 7.723 3.1856 6.6231
U-251MG GDSC1; CTRP2 5.0643 8.5676 3.8954 11.1199
LN-229 GDSC1; CTRP2 5.0925 8.6912 3.863 11.1864
DBTRG-05MG GDSC1; CTRP2 5.2223 11.7561 2.4775 16.4921
SNB-75 GDSC1; CTRP2 5.2696 8.6357 4.0575 9.9773
D-392MG GDSC1 5.3397 11.4806 1.5514 17.0703
8-MG-BA GDSC1; CTRP2 5.463 9.4796 3.8211 10.5271
H4 GDSC1 5.5318 9.849 2.4902 10.3833
SNU-466 CTRP2 5.6119 8.7583 4.3121 8.1614
GOS-3 CTRP2 5.6944 12.7487 2.3963 15.8023
SNU-489 CTRP2 5.7225 8.0357 4.7692 6.0158
Onda 10 GDSC1 5.807 10.7056 2.2669 11.1601
KNS-42 GDSC1 5.8208 17.0814 -0.8558 26.3935
CCF-STTG1 CTRP2 5.9018 12.069 2.9125 13.349
KNS-81 CTRP2 6.0342 10.7385 3.6888 9.9079
U-87MG ATCC GDSC1; CTRP2 6.1522 14.6631 1.8246 17.0149
TM-31 CTRP2 6.3492 12.9851 2.8247 12.8309
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 4.1683 6.0198 3.3418 8.3035
ETK-1 GDSC1 4.2028 8.066 2.3497 15.7441
TGBC1TKB GDSC1 4.7708 6.6393 3.5127 4.9282
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-265 CTRP2 -2.345 2.2401 -2.4186 55.5684
JHUEM-1 CTRP2 -0.4689 6.006 -1.0533 44.3671
JHUEM-2 CTRP2 1.6622 5.6814 1.356 30.2208
JHUEM-7 CTRP2 1.7776 5.2989 1.5683 29.1328
AN3-CA GDSC1; CTRP2 2.8875 5.4096 2.7494 21.5055
JHUEM-3 CTRP2 2.9712 15.9596 -1.6604 33.9416
HEC-1-B CTRP2 3.565 8.2896 2.5127 20.4059
HEC-59 CTRP2 3.7825 6.8083 3.332 16.6909
MFE-280 GDSC1 3.8083 13.3789 -0.6414 32.0654
RL95-2 GDSC1; CTRP2 4.0643 6.7655 3.6511 14.6829
HEC-6 CTRP2 4.0673 7.0765 3.5377 15.1045
KLE GDSC1; CTRP2 4.3422 8.3244 3.2953 15.3165
HEC-1-A CTRP2 4.3551 7.2582 3.7702 13.416
HEC-151 CTRP2 4.6051 6.1425 4.4458 10.1497
ESS-1 GDSC1; CTRP2 4.9091 8.4078 3.8211 11.7931
HEC-251 CTRP2 5.2797 7.9619 4.3922 8.5768
EN GDSC1; CTRP2 5.2856 9.6555 3.5731 11.941
MFE-296 GDSC1; CTRP2 5.62 9.0056 4.1968 8.6254
HEC-108 CTRP2 5.6265 7.0365 5.1681 4.578
MFE-319 GDSC1; CTRP2 5.8133 11.079 3.332 11.8216
EFE-184 CTRP2 6.0162 9.4724 4.3069 7.3571
HEC-50B CTRP2 6.1512 10.465 3.9225 8.7091
Ishikawa (Heraklio) 02 ER- CTRP2 5.7117 6.9536 5.2896 3.879
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-1M GDSC1 1.2818 6.8336 0.0935 42.143
KMRC-2 CTRP2 2.6613 6.6225 2.1797 24.2306
RXF 393L GDSC1 2.9457 9.1282 0.6937 30.8306
HA7-RCC GDSC1 3.036 5.8781 2.3196 21.0741
LB1047-RCC GDSC1 3.2502 6.2809 2.3508 19.8052
KTCTL-140 GDSC1 3.5554 7.5232 2.0449 20.5339
KTCTL-21 GDSC1 3.6325 7.4337 2.1598 19.4111
OS-RC-2 GDSC1; CTRP2 3.8066 9.9092 2.0334 21.557
KMRC-3 CTRP2 4.0166 9.9915 2.2022 20.391
KTCTL-26A GDSC1 4.0311 6.0139 3.2228 9.7806
SNU-1272 CTRP2 4.2454 8.9275 2.9233 17.0328
LB996-RCC GDSC1 4.2467 6.2812 3.2789 8.5007
TK-10 GDSC1 4.2939 8.7121 2.1034 17.1259
UO-31 GDSC1; CTRP2 4.3234 7.8452 3.4885 14.602
KTCTL-195 GDSC1 4.434 12.8179 0.167 26.9891
NCC021 GDSC1 4.533 10.8898 1.2122 21.7142
KMRC-1 GDSC1; CTRP2 4.5509 7.9177 3.6894 13.2163
BB65-RCC GDSC1 4.6144 6.8685 3.2834 7.1865
BFTC-909 GDSC1; CTRP2 4.6197 7.9296 3.7538 12.7834
SW156 GDSC1 4.9322 12.8531 0.5536 23.6254
A-704 GDSC1 5.0165 9.9615 2.058 14.9073
TUHR4TKB CTRP2 5.0472 8.8307 3.7526 11.7445
TUHR14TKB CTRP2 5.1053 10.516 2.9847 14.7422
TUHR10TKB CTRP2 5.2054 8.2439 4.1858 9.5979
Caki-2 CTRP2 5.219 11.2579 2.7214 15.5424
786-O GDSC1; CTRP2 5.342 9.9754 3.4667 12.2556
VMRC-RCW GDSC1; CTRP2 5.3532 10.4094 3.2621 13.0706
A-498 GDSC1 5.3913 7.3949 3.5587 3.073
SN12C GDSC1 5.3983 7.5577 3.4887 3.5434
KMRC-20 GDSC1; CTRP2 5.854 9.1599 4.3253 7.6016
Caki-1 GDSC1; CTRP2 6.266 12.9043 2.7973 13.0973
LB2241-RCC GDSC1 6.3731 9.5384 3.1596 3.8683
VMRC-RCZ GDSC1; CTRP2 6.4099 15.5321 1.6016 17.3079
ACHN GDSC1; CTRP2 6.4949 12.4868 3.1905 11.0917
SW13 GDSC1 7.1311 8.604 3.8522 0.1259
KTCTL-13 GDSC1 7.4044 9.3507 3.6944 0.336
769-P GDSC1 7.4782 17.2564 0.2585 17.8988
CAL-54 GDSC1 7.723 17.7115 0.2054 17.5688
RCC10RGB GDSC1; CTRP2 10.1018 21.2738 1.4877 11.8046
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C1 GDSC1; CTRP2 1.0542 4.7686 0.8862 33.7889
GP2d CTRP2 1.1824 4.7281 1.031 32.8875
MDST8 GDSC1; CTRP2 2.164 6.1846 1.7705 27.2052
SK-CO-1 CTRP2 2.9344 5.4956 2.7829 21.24
SNU-407 GDSC1; CTRP2 3.0902 7.8721 2.1866 22.9445
HCT 116 GDSC1; CTRP2 3.1804 6.4241 2.8074 20.3986
NCI-H747 GDSC1; CTRP2 3.2499 5.9446 3.0213 19.4138
COLO 320HSR GDSC1 3.4017 10.2799 0.5451 29.4175
LS513 GDSC1; CTRP2 3.4458 6.8586 2.9508 19.0886
SNU-175 GDSC1 3.457 9.6782 0.8928 27.61
GP5d GDSC1 3.4844 11.4367 0.0445 31.0387
LS180 GDSC1; CTRP2 3.5063 6.3505 3.1852 18.0446
NCI-H716 GDSC1; CTRP2 3.5329 7.8599 2.6589 19.9408
T84 GDSC1; CTRP2 3.651 7.0757 3.0928 17.9668
SW48 GDSC1; CTRP2 3.7843 6.517 3.4343 16.3043
SNU-C5 GDSC1; CTRP2 3.8201 7.2634 3.2018 17.0771
CCK-81 GDSC1; CTRP2 4.0058 6.391 3.7161 14.6104
SW948 GDSC1; CTRP2 4.055 6.5189 3.7274 14.4241
SNU-1040 GDSC1 4.103 7.5139 2.5401 14.7375
LS1034 GDSC1; CTRP2 4.1499 9.5029 2.5619 18.6838
RKO GDSC1; CTRP2 4.227 9.9789 2.4139 19.0604
SNU-C2B GDSC1 4.2936 9.1896 1.8645 18.7162
SNU-1033 CTRP2 4.3185 7.7161 3.5394 14.4148
LoVo GDSC1; CTRP2 4.3193 7.5556 3.6088 14.1411
C2BBe1 GDSC1; CTRP2 4.3554 7.8283 3.5289 14.359
NCI-H508 CTRP2 4.3627 6.7663 3.9715 12.6224
SNU-503 CTRP2 4.3882 9.2548 2.9127 16.7173
LS411N GDSC1; CTRP2 4.4046 7.2012 3.8456 12.9895
COLO 678 GDSC1; CTRP2 4.4848 9.481 2.9004 16.5287
SW837 GDSC1 4.5182 7.9184 2.6845 12.1236
COLO205 GDSC1; CTRP2 4.6009 6.5956 4.2904 10.7391
HCT 15 GDSC1; CTRP2 4.6122 11.8068 1.8971 20.0665
SW626 GDSC1 4.6496 10.2261 1.6383 18.8376
HCC2998 GDSC1 4.7024 8.3747 2.6033 12.0994
LS123 GDSC1; CTRP2 4.7211 6.8442 4.3239 10.2741
HT115 GDSC1; CTRP2 4.7572 5.2993 4.7546 8.5842
HT-55 GDSC1; CTRP2 4.8804 6.4085 4.6589 8.5512
CaR-1 GDSC1 4.8875 7.6955 3.0801 7.9064
SNU-C4 CTRP2 4.9759 6.1142 4.8585 7.5319
SW620 GDSC1; CTRP2 5.0446 8.1506 4.0747 10.4349
SW1417 GDSC1; CTRP2 5.062 8.461 3.9441 10.9262
CL-11 GDSC1; CTRP2 5.1522 7.5798 4.4478 8.6583
KM12 GDSC1; CTRP2 5.1749 7.6638 4.4312 8.6696
CW-2 GDSC1; CTRP2 5.2916 9.2469 3.7794 11.0763
COLO201 CTRP2 5.3099 7.7079 4.5423 7.8907
DLD-1 CTRP2 5.3492 6.6865 5.0487 5.7547
OUMS-23 CTRP2 5.4779 7.5611 4.7743 6.5432
SNU-81 GDSC1 5.5776 8.1427 3.3289 4.2776
HCC-56 CTRP2 5.614 6.5461 5.3827 3.7415
SNU-61 GDSC1; CTRP2 5.7346 12.4733 2.5682 15.0522
RCM-1 [Human ESC] GDSC1; CTRP2 5.7794 8.4987 4.5899 6.6451
SW1116 GDSC1; CTRP2 5.8296 6.8728 5.4399 2.9885
HCT 8 CTRP2 5.8587 6.4213 5.6853 1.9107
HT-29 GDSC1; CTRP2 5.9252 11.9941 2.9696 13.0725
SW1463 GDSC1 6.3078 8.1645 3.6969 0.962
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 4.1176 14.5867 -0.9817 31.9767
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Li-7 CTRP2 1.28 5.5653 0.9675 32.7558
SNU-182 CTRP2 1.7411 7.6779 0.8189 31.6628
SNU-387 GDSC1; CTRP2 2.1737 7.4525 1.3665 28.5462
SNU-878 CTRP2 2.2736 4.2359 2.2478 25.2081
SNU-398 GDSC1; CTRP2 2.306 5.778 2.0341 25.8419
JHH-4 GDSC1; CTRP2 2.9657 5.5115 2.8136 21.0339
JHH-1 GDSC1; CTRP2 3.0407 5.0676 2.9722 20.2432
HLE GDSC1 3.1396 7.1812 1.8177 23.9366
SNU-886 CTRP2 3.4891 7.1792 2.8805 19.2272
Hep 3B2.1-7 GDSC1; CTRP2 3.517 6.4892 3.153 18.1306
SNU-449 GDSC1; CTRP2 3.5281 7.7952 2.6802 19.8734
SNU-423 GDSC1; CTRP2 3.5292 8.6506 2.3202 21.2276
JHH-2 GDSC1; CTRP2 3.692 7.3667 3.0252 18.1074
SNU-475 GDSC1; CTRP2 3.7013 8.9081 2.3832 20.5282
HuH-6 CTRP2 3.8978 8.9194 2.5776 19.2705
SNU-761 CTRP2 4.4197 7.7305 3.6376 13.762
Hep-G2 CTRP2 4.7117 8.4938 3.587 13.2225
JHH-5 CTRP2 4.8767 6.2725 4.7012 8.404
Huh-7 GDSC1 5.1824 7.8157 3.2297 5.9415
HuH-1 GDSC1; CTRP2 5.2958 7.5082 4.6229 7.5968
JHH-6 GDSC1; CTRP2 5.3043 10.3627 3.2412 13.2623
JHH-7 GDSC1 5.3177 7.9798 3.2414 5.5093
HLF CTRP2 5.5464 10.6072 3.3358 12.3561
Hep-G2/C3A GDSC1 6.2265 7.7497 3.8195 0.5384
SK-HEP-1 GDSC1; CTRP2 7.2607 11.6013 4.2027 5.6813
PLC/PRF/5 CTRP2 14.7591 54.5019 -11.3611 29.2175
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 208 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1048 GDSC1 -2.302 0.7159 -2.3239 77.5671
NCI-H1341 CTRP2 -0.6181 3.749 -0.7526 44.645
NCI-H64 GDSC1 -0.542 1.9982 -0.576 60.0846
NCI-H446 GDSC1; CTRP2 0.4134 4.0733 0.3037 37.8461
NCI-H847 GDSC1 0.6796 4.5715 0.2761 46.3792
NCI-H2171 GDSC1 1.1425 3.7815 0.9834 40.5014
DMS 273 GDSC1; CTRP2 1.2126 7.7383 0.2281 35.1077
HCC44 GDSC1; CTRP2 1.2986 4.8773 1.1307 32.171
COR-L311 GDSC1 1.3202 5.397 0.7003 40.2005
DV-90 CTRP2 1.3987 4.3006 1.3225 31.2042
NCI-H211 GDSC1; CTRP2 1.6087 8.4847 0.372 33.3765
EMC-BAC-2 GDSC1 1.6829 6.6334 0.596 38.0978
NCI-H520 GDSC1; CTRP2 1.8429 7.3982 1.0293 30.6855
NCI-H2795 GDSC1 1.9028 7.1102 0.6166 36.6697
NCI-H209 GDSC1 1.9401 10.082 -0.7229 40.1509
SBC-3 GDSC1 2.0357 6.7915 0.8929 34.7866
EMC-BAC-1 GDSC1 2.0769 10.0662 -0.5838 39.1771
NCI-H1648 GDSC1 2.1346 7.3795 0.7316 34.8756
Lu-139 GDSC1 2.1517 7.4393 0.7217 34.8175
NCI-H1975 GDSC1; CTRP2 2.1585 5.0585 2.0264 26.3375
NCI-H2110 GDSC1; CTRP2 2.1644 4.9482 2.0511 26.2335
EPLC-272H GDSC1; CTRP2 2.3373 6.2233 1.9486 26.0433
Lu-135 GDSC1 2.3628 4.8591 2.0163 26.7498
LCLC-97TM1 GDSC1; CTRP2 2.4726 8.3021 1.3609 27.6485
NCI-H2135 GDSC1 2.4966 6.4788 1.5026 29.1317
NCI-H1563 GDSC1; CTRP2 2.532 6.0922 2.198 24.5609
IST-SL1 GDSC1 2.5523 4.3965 2.3698 23.3165
LC-2/ad GDSC1 2.6111 9.3208 0.2848 34.0483
NCI-H596 GDSC1 2.6247 8.6772 0.6072 32.7558
NCI-H1184 CTRP2 2.6309 5.3856 2.4762 23.2715
NCI-H1688 GDSC1 2.6494 6.8613 1.4849 28.4064
NCI-H1734 GDSC1; CTRP2 2.7048 5.8571 2.4491 23.1357
NCI-H2227 GDSC1 2.728 11.5803 -0.7084 36.5027
CPC-N GDSC1 2.7402 11.3264 -0.5723 36.0965
NCI-H647 GDSC1; CTRP2 2.7408 9.0191 1.3458 26.9035
COR-L303 GDSC1 2.8065 8.8055 0.719 31.3896
NCI-H23 GDSC1; CTRP2 2.81 6.9133 2.2442 23.5524
NCI-H187 GDSC1 2.856 10.0201 0.1748 33.2798
RERF-LC-MS GDSC1; CTRP2 2.8663 6.8991 2.31 23.1466
NCI-H69 GDSC1; CTRP2 2.9501 6.8085 2.4317 22.4551
COR-L23 GDSC1 3.0522 9.1878 0.7639 30.0229
HCC1588 CTRP2 3.0878 7.5936 2.2936 22.5592
COR-L105 GDSC1; CTRP2 3.097 8.9521 1.7437 24.5192
Lu-65 GDSC1; CTRP2 3.1046 10.6045 1.0135 26.9488
NCI-H810 GDSC1; CTRP2 3.1574 5.5453 3.0146 19.7249
NCI-H1944 GDSC1; CTRP2 3.1848 8.5273 2.0163 23.2977
NCI-H510A GDSC1 3.1942 4.457 3.0518 15.0419
Calu-3 GDSC1; CTRP2 3.2818 7.88 2.3861 21.6655
NCI-H1703 GDSC1; CTRP2 3.3054 7.9516 2.3819 21.6147
CAL-12T GDSC1; CTRP2 3.3086 6.1966 3.0158 19.2551
HCC33 GDSC1 3.3131 12.4518 -0.6116 33.8456
NCI-H82 GDSC1 3.3803 8.0255 1.6368 23.9311
NCI-H1694 GDSC1; CTRP2 3.4128 7.0175 2.8583 19.5288
NCI-H2009 GDSC1; CTRP2 3.4139 6.5417 3.0239 18.9109
NCI-H1876 GDSC1 3.4541 8.1341 1.6518 23.5075
NCI-H358 GDSC1; CTRP2 3.4601 6.9039 2.9502 19.0494
DMS 114 GDSC1; CTRP2 3.4805 9.7544 1.7787 23.3406
NCI-H1623 GDSC1; CTRP2 3.4823 6.2779 3.1812 18.1308
SBC-1 GDSC1 3.5125 5.6597 2.8989 14.5375
NCI-H292 GDSC1; CTRP2 3.523 8.3213 2.4556 20.7361
ChaGo-K-1 GDSC1; CTRP2 3.5292 7.4088 2.8355 19.2831
Lu-99 CTRP2 3.5427 6.8478 3.0592 18.4037
HCC95 CTRP2 3.6288 9.7114 1.9472 22.3384
NCI-H526 GDSC1; CTRP2 3.6416 7.5163 2.9125 18.6766
Lu-134-A GDSC1 3.6435 10.4615 0.6699 27.8561
HCC4006 CTRP2 3.6798 7.4901 2.9634 18.3765
HCC827 GDSC1; CTRP2 3.8098 6.4954 3.4692 16.1001
LUDLU-1 CTRP2 3.8292 7.5177 3.1104 17.4014
SK-MES-1 GDSC1; CTRP2 3.8772 6.7862 3.442 16.0057
NCI-H1581 GDSC1; CTRP2 3.8809 5.5642 3.7949 14.7081
NCI-H2196 GDSC1; CTRP2 3.9492 9.1863 2.5083 19.4025
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 3.9874 7.4603 3.3005 16.2359
NCI-H1304 GDSC1 4.0194 5.1929 3.6143 6.7829
NCI-H3122 GDSC1 4.0246 8.6296 1.9155 19.4277
RERF-LC-Ad2 CTRP2 4.0461 11.0276 1.74 22.0093
DMS 53 GDSC1; CTRP2 4.0527 6.0379 3.8725 13.8991
NCI-H1666 GDSC1; CTRP2 4.064 9.3109 2.5658 18.8868
NCI-H1339 CTRP2 4.0677 8.9985 2.7129 18.3079
NCI-H1435 GDSC1; CTRP2 4.0685 6.1517 3.8578 13.9043
NCI-H1568 GDSC1; CTRP2 4.0882 7.4054 3.4291 15.4639
NCI-H2085 GDSC1; CTRP2 4.0966 8.1646 3.1159 16.6601
NCI-H1770 GDSC1 4.1015 5.128 3.7231 5.5868
NCI-H522 GDSC1; CTRP2 4.1104 9.442 2.5512 18.8249
PC-14 GDSC1 4.1313 6.6275 3.0066 11.0704
NCI-H2731 GDSC1 4.1507 10.5325 1.0728 23.8798
ABC-1 GDSC1 4.1705 9.5857 1.5628 21.0655
NCI-H2081 GDSC1; CTRP2 4.1814 6.393 3.9064 13.39
EBC-1 GDSC1; CTRP2 4.1925 7.4489 3.5208 14.825
LK-2 GDSC1 4.2014 6.576 3.0929 10.1289
HCC78 GDSC1; CTRP2 4.2028 6.9265 3.7398 13.9542
T3M-10 CTRP2 4.2087 11.5123 1.6623 21.8813
HCC2935 CTRP2 4.2088 6.4158 3.9287 13.2271
NCI-H841 GDSC1; CTRP2 4.2129 8.0414 3.2892 15.6755
A-427 GDSC1 4.2148 5.9591 3.4125 7.5695
NCI-H1781 GDSC1 4.2253 5.1638 3.818 4.339
Sq-1 CTRP2 4.2482 10.3427 2.2617 19.587
NCI-H524 GDSC1; CTRP2 4.2558 7.2925 3.6517 14.1457
COLO 668 GDSC1; CTRP2 4.2651 9.7621 2.5535 18.4282
NCI-H2591 GDSC1 4.3061 9.4952 1.7221 19.5739
SW1271 GDSC1; CTRP2 4.3682 10.8568 2.1301 19.7882
NCI-H2347 GDSC1 4.3733 10.4269 1.3122 21.7464
NCI-H2170 GDSC1; CTRP2 4.387 6.619 4.0516 12.2506
HCC2279 CTRP2 4.4116 10.6142 2.2884 19.0864
NCI-H2030 GDSC1; CTRP2 4.4167 10.4015 2.3955 18.6652
COR-L95 GDSC1; CTRP2 4.4208 8.9224 3.0999 15.894
UMC-11 GDSC1 4.4328 6.1863 3.4804 6.2456
NCI-H661 GDSC1; CTRP2 4.4428 9.4058 2.895 16.6528
NCI-H1436 GDSC1 4.4733 7.9246 2.6451 12.577
HOP-62 GDSC1; CTRP2 4.4798 8.6359 3.2912 14.9846
NCI-H1838 GDSC1; CTRP2 4.4861 6.6216 4.1574 11.5685
COR-L88 GDSC1 4.4977 6.3916 3.4297 6.4246
Lu-165 GDSC1 4.5027 9.3492 1.9573 17.3375
HCC1833 CTRP2 4.5057 12.1591 1.626 21.2917
NCI-H720 GDSC1 4.5176 6.1561 3.5624 5.3176
LXF 289 GDSC1; CTRP2 4.5309 7.3836 3.9019 12.4294
Lu-99A GDSC1 4.5407 9.8829 1.7216 18.7121
NCI-H1915 GDSC1; CTRP2 4.544 8.8519 3.2545 14.9719
NCI-H2122 GDSC1; CTRP2 4.5679 6.329 4.3472 10.6223
NCI-H196 GDSC1; CTRP2 4.59 9.8041 2.848 16.4818
A-549 GDSC1; CTRP2 4.5994 7.0212 4.1241 11.3794
NCI-H3255 GDSC1 4.6129 8.3942 2.5229 12.9963
NCI-H2373 GDSC1 4.6925 10.6941 1.4391 19.8715
NCI-H2405 GDSC1; CTRP2 4.7528 8.3964 3.6729 12.775
PaCa-3 GDSC1 4.7671 9.5282 2.0798 15.591
NCI-H2869 GDSC1 4.7681 11.2016 1.2465 20.6967
NCI-H1793 GDSC1; CTRP2 4.8058 9.8397 3.0364 15.2193
MOR/CPR CTRP2 4.8411 6.1495 4.701 8.5106
VMRC-LCD CTRP2 4.8461 8.8297 3.56 13.0058
Ms-1 GDSC1 4.849 14.2257 -0.1978 26.9997
NCI-H2029 GDSC1; CTRP2 4.8555 6.7891 4.4882 9.271
NCI-H1836 GDSC1 4.8657 6.3515 3.7166 3.1265
NCI-H1155 GDSC1; CTRP2 4.8845 7.4633 4.2315 10.2014
NCI-H838 GDSC1; CTRP2 4.9007 9.0303 3.5168 13.0516
NCI-H2141 GDSC1; CTRP2 4.9131 6.695 3.5846 2.4026
LK2 CTRP2 4.9291 8.9441 3.5853 12.7058
NCI-H1355 GDSC1; CTRP2 4.9713 6.7939 4.6086 8.4883
NCI-H1693 GDSC1 4.993 13.5645 0.2472 24.7717
NCI-H748 GDSC1 4.9946 9.8105 2.1162 14.5882
EKVX GDSC1; CTRP2 5.0197 7.2199 4.4774 8.8749
NCI-H727 GDSC1; CTRP2 5.0258 7.6467 4.291 9.6046
NCI-H1105 CTRP2 5.0295 11.1822 2.5874 16.4905
NCI-H322M GDSC1 5.0371 11.4661 1.3269 19.34
NCI-H2444 GDSC1; CTRP2 5.0393 7.9861 4.1469 10.1543
RERF-LC-A1 CTRP2 5.0417 9.0283 3.6521 12.1689
NCI-H2228 GDSC1; CTRP2 5.0778 10.3663 3.0331 14.6088
NCI-H1573 GDSC1; CTRP2 5.105 8.4291 4.0008 10.5922
NCI-H2126 CTRP2 5.1063 9.5908 3.4394 12.8922
NCI-H1299 GDSC1; CTRP2 5.1106 10.1839 3.1529 14.0506
NCI-H2023 GDSC1; CTRP2 5.1296 8.1337 4.1654 9.861
NCI-H1755 GDSC1; CTRP2 5.1374 14.8148 0.8822 22.3453
HCC15 GDSC1; CTRP2 5.1701 9.0963 3.7401 11.5122
NCI-H1395 CTRP2 5.1949 8.0049 4.2898 9.197
NCI-H1650 GDSC1; CTRP2 5.1977 9.6819 3.4795 12.522
LOU-NH91 GDSC1; CTRP2 5.212 8.9988 3.8268 11.06
LC-1/sq GDSC1 5.2246 10.6305 1.8847 15.3764
NCI-H2342 GDSC1; CTRP2 5.257 7.0666 4.7874 7.0301
HCC2108 CTRP2 5.2627 11.5474 2.6171 15.8583
NCI-H1963 GDSC1 5.2678 7.5872 3.3942 4.5137
SHP-77 GDSC1; CTRP2 5.2967 6.7458 4.969 6.2069
HOP-92 GDSC1; CTRP2 5.3001 7.6448 4.5628 7.8308
HCC1438 CTRP2 5.3076 8.0878 4.3585 8.6495
NCI-H1993 GDSC1 5.3193 11.0005 1.773 15.7857
NCI-H345 GDSC1 5.3237 6.2599 4.0067 0.4848
NCI-H1869 GDSC1; CTRP2 5.3299 8.5821 4.14 9.499
NCI-H1373 CTRP2 5.4922 9.8144 3.6815 11.0437
NCI-H1792 GDSC1; CTRP2 5.496 11.9043 2.6458 15.2446
Calu-6 GDSC1; CTRP2 5.5323 9.654 3.7969 10.4789
DMS 454 CTRP2 5.5353 9.5191 3.8665 10.1831
COR-L321 GDSC1 5.5842 14.8897 0.0496 23.7591
NCI-H2722 GDSC1 5.5843 11.8968 1.5281 16.461
NCI-H2291 GDSC1; CTRP2 5.5862 9.6502 3.8467 10.1573
NCI-H2369 GDSC1 5.5889 9.7831 2.5615 9.7255
NCI-H2087 GDSC1; CTRP2 5.6287 9.8646 3.7777 10.3549
SBC-5 GDSC1; CTRP2 5.6692 7.8708 4.8023 5.9934
NCI-H1651 GDSC1 5.6705 7.4288 3.6963 1.701
NCI-H1437 GDSC1 5.6773 12.4559 1.3218 17.3667
NCI-H2595 GDSC1 5.7172 11.0013 2.0615 12.7653
NCI-H2804 GDSC1 5.7299 11.6255 1.7667 14.5979
HCC1171 CTRP2 5.7356 14.6756 1.4689 19.1158
BEN GDSC1; CTRP2 5.7421 7.3014 5.1491 4.3907
NCI-H2106 CTRP2 5.7579 10.4657 3.5906 10.8658
LCLC-103H GDSC1; CTRP2 5.7599 8.8244 4.4108 7.436
NCI-H513 GDSC1 5.8779 11.2833 2.0372 12.4771
NCI-H1092 GDSC1; CTRP2 5.9099 10.3739 3.7665 9.8286
RERF-LC-Ad1 CTRP2 5.9606 10.4442 3.7743 9.6961
HCC1195 CTRP2 5.9608 14.5649 1.7142 17.7926
NCI-H2803 GDSC1 5.9621 12.7003 1.4085 16.0555
HCC366 CTRP2 6.0376 10.2579 3.932 8.8873
NCI-H889 CTRP2 6.1153 7.8414 5.2043 3.3968
NCI-H441 GDSC1; CTRP2 6.1301 10.8059 3.7347 9.5323
NCI-H650 GDSC1; CTRP2 6.1833 10.8086 3.7771 9.2552
NCI-H322 CTRP2 6.1954 8.0869 5.146 3.4947
SK-LU-1 GDSC1; CTRP2 6.2879 12.6917 2.9214 12.5614
NCI-H2461 GDSC1 6.3619 11.2956 2.3532 9.1875
NCI-H2172 GDSC1; CTRP2 6.4072 11.5995 3.5631 9.7269
KNS-62 CTRP2 6.4413 9.6003 4.5855 5.4076
DMS 79 GDSC1; CTRP2 6.5151 16.1813 1.3627 17.9335
NCI-H460 GDSC1; CTRP2 6.5846 10.0301 4.4819 5.5956
LC-1/sq-SF CTRP2 6.698 14.659 2.2689 14.3343
Calu-1 CTRP2 6.721 9.7924 4.7 4.4711
SW1573 GDSC1 6.7312 9.0407 3.5415 1.2643
RERF-LC-KJ GDSC1 6.7499 15.1993 0.7497 17.4088
NCI-H2818 GDSC1 6.8009 12.0538 2.2746 8.698
RERF-LC-Sq1 GDSC1 7.0538 14.866 1.116 14.8128
NCI-H226 GDSC1; CTRP2 7.7692 13.5375 3.6196 7.2751
IA-LM GDSC1; CTRP2 7.9353 11.538 4.6676 2.996
NCI-H2286 CTRP2 10.0548 19.7808 2.1615 9.6111
Hs 888.Lu CTRP2 3.2451 7.4927 2.5003 21.3445
⏷ Show the Full List of 208 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 1.4641 7.7876 -0.1315 41.4885
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 0.8825 5.4034 0.5722 35.348
Aska-SS CTRP2 1.2238 6.8656 0.5384 34.2302
Rh41 GDSC1; CTRP2 0.5682 2.5847 0.5635 36.4984
EW-8 GDSC1 1.7347 4.2075 1.5288 33.5714
A-204 GDSC1; CTRP2 2.3289 7.4373 1.5391 27.4864
Hs 633.T GDSC1 2.5584 5.3615 2.0394 25.4959
G-401 GDSC1; CTRP2 2.6961 6.6682 2.2028 24.0428
SW982 GDSC1; CTRP2 2.7665 7.3247 2.0509 24.378
Rh18 CTRP2 3.1584 6.9676 2.6019 21.2181
TTC-709 CTRP2 3.205 7.47 2.4662 21.5861
TE 441.T GDSC1; CTRP2 3.2996 7.7096 2.4732 21.2906
Tm87-16 CTRP2 3.4126 7.3647 2.7282 20.0166
RD GDSC1; CTRP2 3.4772 6.4183 3.1324 18.3245
G-402 GDSC1; CTRP2 3.6373 9.8736 1.8814 22.5543
GCT GDSC1; CTRP2 3.8604 7.0852 3.3134 16.5395
VA-ES-BJ GDSC1 4.114 6.1049 3.2517 9.2224
SW872 GDSC1 4.237 7.3969 2.7131 12.9258
Rh30 GDSC1 4.2761 5.9459 3.4715 6.8747
BT-16 CTRP2 4.3412 6.3092 4.1071 12.1776
MFH-ino GDSC1 4.4224 7.2285 2.9515 10.4214
KYM-1 GDSC1; CTRP2 4.4927 5.7039 4.4303 10.5515
Hs 729.T CTRP2 4.6015 11.1031 2.2308 18.851
MES-SA GDSC1; CTRP2 5.1384 7.4197 4.5077 8.4509
TE 617.T CTRP2 5.1584 7.1579 4.6463 7.8454
HT-1080 GDSC1; CTRP2 5.2836 7.7444 4.4995 8.1285
RKN GDSC1; CTRP2 5.8701 12.6221 2.6092 14.6161
BT-12 CTRP2 6.0023 6.8188 5.6216 1.8602
SK-LMS-1 GDSC1; CTRP2 6.1246 16.746 0.7603 20.6671
SK-UT-1 GDSC1; CTRP2 6.2105 11.1461 3.6307 9.8123
SW684 GDSC1 6.2754 7.4857 3.9322 0.1957
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 1.0761 8.3824 -0.1569 36.5298
A2780 GDSC1; CTRP2 2.0274 5.6323 1.7658 27.6547
SNU-840 CTRP2 2.2389 8.2799 1.1221 29.1396
IGROV-1 GDSC1; CTRP2 2.2909 5.861 1.9967 26.0199
OVISE GDSC1 2.8078 9.4996 0.3838 32.7388
SNU-119 CTRP2 2.8665 7.1719 2.2141 23.4935
OVKATE GDSC1 2.9712 10.6321 -0.0191 33.4291
COV434 CTRP2 2.9907 6.8986 2.4448 22.2874
Caov-3 GDSC1; CTRP2 3.0092 8.2201 1.9604 23.9969
COV644 CTRP2 3.1433 6.1972 2.8353 20.4085
OAW28 GDSC1; CTRP2 3.2713 7.8838 2.3734 21.7421
COV362 CTRP2 3.5646 9.1865 2.12 21.8764
OVSAHO CTRP2 3.5679 7.4534 2.8591 19.085
ONCO-DG-1 CTRP2 3.7412 7.283 3.1102 17.6464
FU-OV-1 GDSC1; CTRP2 3.9991 9.9013 2.2273 20.3415
OAW42 GDSC1; CTRP2 4.0229 7.6239 3.2706 16.2548
SK-OV-3 GDSC1; CTRP2 4.0574 9.5792 2.435 19.4056
OVK18 GDSC1; CTRP2 4.1522 7.3515 3.5185 14.9437
ES-2 GDSC1 4.218 5.1077 3.8394 4.1995
OV7 CTRP2 4.2234 13.9688 0.4782 25.693
OVTOKO GDSC1; CTRP2 4.226 10.1153 2.3483 19.3131
JHOM-1 CTRP2 4.2673 8.1434 3.3 15.4911
JHOS-2 GDSC1; CTRP2 4.2858 10.268 2.3336 19.2216
OC 314 GDSC1; CTRP2 4.2907 9.0751 2.9002 17.0095
SNU-8 CTRP2 4.2986 6.4422 4.0174 12.6347
OVCAR-4 GDSC1; CTRP2 4.3624 10.0215 2.525 18.2984
JHOC-5 CTRP2 4.3885 6.8291 3.9754 12.535
MCAS CTRP2 4.4003 6.9408 3.945 12.6182
Kuramochi GDSC1; CTRP2 4.5217 12.7463 1.353 22.1997
Caov-4 GDSC1 4.6971 8.1916 2.6902 11.4704
TOV-112D GDSC1; CTRP2 4.7624 9.5284 3.1453 14.8831
RMG-I GDSC1; CTRP2 4.8979 10.3933 2.8535 15.7376
OVCAR-5 GDSC1; CTRP2 5.2301 10.7099 3.0026 14.3937
TYK-nu GDSC1; CTRP2 5.2335 9.3298 3.6851 11.5953
HEY A8 CTRP2 5.4205 10.2208 3.4159 12.2949
DOV13 GDSC1 5.663 8.7544 3.0987 5.712
OV-90 GDSC1; CTRP2 5.67 9.9959 3.7486 10.3903
TOV-21G GDSC1; CTRP2 5.7495 7.1021 5.2533 3.942
OV56 GDSC1; CTRP2 5.8496 9.2936 4.2547 7.9065
OVCAR-8 GDSC1; CTRP2 5.9016 9.54 4.1762 8.1313
OVCAR-3 GDSC1 5.9646 8.1874 3.5256 2.2745
EFO-27 GDSC1; CTRP2 6.0051 9.2173 4.4251 6.8822
EFO-21 GDSC1; CTRP2 6.048 12.3485 2.8953 13.1284
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 3.6715 5.9596 3.4775 16.4847
H-STS CTRP2 6.0099 8.6059 4.7348 5.5715
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.9216 9.6466 2.2691 20.3826
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 3.1515 8.4626 1.2103 27.3954
NCI-H28 GDSC1; CTRP2 3.4933 6.3376 3.1751 18.1201
NCI-H2452 GDSC1; CTRP2 4.2439 9.6963 2.5637 18.4415
MSTO-211H GDSC1; CTRP2 5.1008 7.8335 4.2788 9.4686
IST-Mes1 GDSC1; CTRP2 5.2561 10.5396 3.1102 13.9012
ACC-MESO-1 CTRP2 5.837 10.0034 3.8895 9.4612
NCI-H2052 GDSC1; CTRP2 6.3014 12.7921 2.8823 12.692
JL-1 CTRP2 7.7428 14.6909 3.0418 9.5894
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 GDSC1 0.2721 8.6478 -1.731 50.3
VCaP GDSC1; CTRP2 2.8282 6.8938 2.2706 23.4026
PC-3 GDSC1 3.2733 8.977 1.0716 27.5466
LNCaP clone FGC GDSC1; CTRP2 4.2719 9.7285 2.5759 18.3245
DU145 GDSC1; CTRP2 5.7682 9.2089 4.2265 8.1908
PaCa-3 CTRP2 6.3273 12.425 3.0867 11.8222
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.2143 5.0207 2.0929 25.9293
A-253 GDSC1; CTRP2 5.7515 8.1772 4.725 6.1384
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.3172 8.8736 1.1628 26.8812
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RF-48 GDSC1 -0.167 6.0867 -1.1512 53.6982
HGC-27 GDSC1; CTRP2 1.4513 3.5693 1.435 30.6543
GSS CTRP2 1.9967 4.1561 1.9653 27.0716
Fu97 GDSC1; CTRP2 2.3474 5.4933 2.1458 25.3216
SNU-1 GDSC1; CTRP2 2.4059 5.8 2.1376 25.1664
IM95 GDSC1; CTRP2 2.5203 6.0991 2.1833 24.6492
23132/87 GDSC1; CTRP2 2.746 5.9046 2.482 22.8915
SNU-668 CTRP2 3.3389 5.656 3.188 18.5449
SNU-620 CTRP2 3.4547 5.3706 3.3695 17.5436
HuG1-N CTRP2 3.4966 9.2755 2.0111 22.4591
NCI-N87 GDSC1; CTRP2 3.5013 6.8041 3.0299 18.6329
TGBC11TKB GDSC1 3.545 5.6482 2.9366 14.1021
NUGC-4 GDSC1; CTRP2 3.548 7.4988 2.8202 19.288
GCIY GDSC1 3.6308 6.8897 2.4247 17.5354
SNU-216 CTRP2 3.8994 6.3125 3.6252 15.2604
ECC10 GDSC1; CTRP2 4.1426 6.9568 3.664 14.4122
LMSU CTRP2 4.1581 10.85 1.9326 21.0343
AGS GDSC1; CTRP2 4.2688 6.7169 3.8889 13.2022
SNU-719 CTRP2 4.3806 10.5059 2.3108 19.0763
KE-39 CTRP2 4.3865 7.3999 3.7444 13.4316
SNU-601 CTRP2 4.6127 7.2236 4.0546 11.6133
RERF-GC-1B GDSC1 4.6375 9.4627 2.0095 16.5107
SH-10-TC CTRP2 4.6398 9.2637 3.1539 15.1414
Hs 746.T GDSC1; CTRP2 4.6866 7.1343 4.1692 10.9676
SNU-5 GDSC1; CTRP2 4.8326 5.9797 4.739 8.3987
SNU-16 GDSC1; CTRP2 4.8816 5.7122 4.8483 7.8601
ECC12 CTRP2 4.9064 8.0134 4.0029 11.0633
MKN28 GDSC1 4.9186 8.342 2.7849 10.0467
MKN74 CTRP2 4.9292 9.5429 3.2967 13.8803
TMK-1 GDSC1 4.9675 10.7874 1.6102 17.9176
MKN1 GDSC1; CTRP2 4.9829 9.1038 3.5598 12.6834
OCUM-1 GDSC1; CTRP2 4.9851 7.9169 4.1257 10.3729
NUGC-3 GDSC1; CTRP2 5.1143 8.4744 3.988 10.6228
SCH GDSC1 5.318 6.529 3.8964 1.047
GSU CTRP2 5.5231 6.1251 5.4515 3.727
HSC-39 GDSC1 6.9545 8.5659 3.8035 0.2497
MKN7 GDSC1; CTRP2 7.2974 14.5009 2.8095 11.2096
MKN45 GDSC1; CTRP2 7.486 8.561 5.6926 0.1668
SNG-M GDSC1; CTRP2 4.2271 7.0991 3.6988 14.0432
SNU-685 CTRP2 4.6983 9.6503 3.0255 15.5162
SNU-1077 CTRP2 4.853 9.9965 3.0049 15.2358
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHT-101 GDSC1; CTRP2 2.5256 6.3509 2.1163 24.8703
B-CPAP GDSC1; CTRP2 2.6565 6.209 2.3008 23.8123
SW579 CTRP2 2.9726 8.5797 1.7729 24.7692
HTC-C3 GDSC1 3.027 8.7584 0.9498 29.2847
8305C GDSC1; CTRP2 3.1295 7.1495 2.5053 21.6586
K5 GDSC1 3.3759 7.4833 1.8972 22.3184
TT GDSC1; CTRP2 3.725 6.331 3.4295 16.4974
CGTH-W-1 GDSC1; CTRP2 3.7775 6.9864 3.2618 16.9695
IHH-4 GDSC1 4.0324 6.8962 2.7862 13.1589
CAL-62 GDSC1; CTRP2 4.1979 7.0544 3.6854 14.1756
ML-1 [Human leukemia] GDSC1; CTRP2 4.5041 11.2975 2.045 19.7782
8505C GDSC1; CTRP2 4.6223 9.2383 3.149 15.2033
KMH-2 GDSC1 4.9841 7.102 3.4375 4.9088
WRO GDSC1 5.1521 8.4412 2.9064 8.4404
FTC-238 CTRP2 5.1818 11.4606 2.5876 16.1514
ASH-3 GDSC1 5.4411 7.1666 3.6884 2.1153
FTC-133 GDSC1; CTRP2 6.5614 9.3927 4.7791 4.3999
TT2609-C02 GDSC1; CTRP2 7.5702 17.0885 1.7366 14.7395
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 1.8519 4.8119 1.737 28.3192
CAL-33 GDSC1; CTRP2 2.2723 5.3804 2.0882 25.7603
SNU-1076 CTRP2 2.5658 5.4221 2.3981 23.7505
PCI-06A GDSC1 2.7297 8.3039 0.8867 31.0288
SNU-1214 CTRP2 2.7351 6.7917 2.2042 23.9204
PE/CA-PJ49 CTRP2 2.8436 6.1706 2.516 22.4704
SCC-25 GDSC1; CTRP2 2.9483 5.646 2.7654 21.2581
SCC-9 GDSC1; CTRP2 3.1124 7.571 2.3285 22.3599
PE/CA-PJ34 (clone C12) CTRP2 3.1952 6.546 2.7849 20.4366
NCI-H3118 GDSC1 3.244 9.1098 0.9795 28.1354
BICR 18 CTRP2 3.2611 7.4931 2.5171 21.2365
Ca9-22 GDSC1 3.423 6.2621 2.529 17.7059
JHU-011 GDSC1 3.4415 7.3504 2.0233 21.1874
CAL-27 GDSC1; CTRP2 3.4999 6.7702 3.0402 18.5983
BICR 56 CTRP2 3.6067 7.1897 3.0024 18.4337
Detroit 562 GDSC1; CTRP2 3.7145 6.3377 3.416 16.5781
BHY GDSC1; CTRP2 3.7225 7.479 3.0131 18.0686
BICR 31 GDSC1; CTRP2 3.7419 7.8148 2.8969 18.4591
BB30-HNC GDSC1 3.7598 6.2262 2.8686 13.6555
HSC-2 GDSC1; CTRP2 3.8342 7.6975 3.0422 17.6495
PCI-04B GDSC1 3.8405 9.175 1.4834 22.852
BICR 78 GDSC1 3.8523 5.7194 3.2015 10.6971
PCI-38 GDSC1 3.9534 7.9942 2.1703 17.9934
LB771-HNC GDSC1 3.9905 7.6587 2.3699 16.4285
YD-8 CTRP2 4.0868 10.7881 1.8935 21.3544
SCC-15 GDSC1 4.1695 7.134 2.787 12.6189
SAT [Human HNSCC] GDSC1 4.1961 8.4193 2.1675 17.0565
KOSC-2 GDSC1 4.2156 9.0255 1.8809 18.9063
BICR 6 CTRP2 4.2604 8.6891 3.0475 16.5052
PE/CA-PJ41 (clone D2) CTRP2 4.3028 7.9504 3.4215 14.9198
OSC-19 GDSC1 4.3405 9.2845 1.8561 18.5943
SAS GDSC1 4.3447 6.9153 3.0442 9.9796
OSC-20 GDSC1 4.4133 10.1578 1.4798 20.6387
BICR 16 CTRP2 4.4449 8.0031 3.5434 14.0689
HO-1-N-1 GDSC1 4.4645 9.1062 2.0475 16.8742
SNU-899 CTRP2 4.5252 7.8911 3.6751 13.3392
HO-1-u-1 GDSC1 4.5398 6.8401 3.2395 7.7743
HSC-4 GDSC1; CTRP2 4.588 6.7642 4.2134 11.0678
PE/CA-PJ15 GDSC1; CTRP2 4.6044 7.4821 3.9358 12.1014
SNU-1041 CTRP2 4.8079 10.4409 2.7464 16.3706
SKN-3 GDSC1 4.8686 8.5906 2.6243 11.3988
BICR 10 GDSC1 4.8924 6.9517 3.4468 5.0878
BICR 22 GDSC1; CTRP2 5.02 6.772 4.6687 8.1226
SCC-4 GDSC1; CTRP2 5.184 10.4997 3.0645 14.2452
HSC-3 GDSC1; CTRP2 5.1929 7.1359 4.6912 7.5778
BB49-HNC GDSC1 5.3675 8.5586 2.9988 7.1646
PCI-15A GDSC1 5.5666 7.5128 3.6055 2.429
SNU-1066 CTRP2 5.5724 9.487 3.9155 9.9001
SNU-46 CTRP2 5.5868 10.9558 3.1976 12.8374
PCI-30 GDSC1 5.9201 10.1995 2.5845 8.705
FaDu GDSC1; CTRP2 6.0358 8.9506 4.5842 6.1542
KON GDSC1 6.0578 7.8615 3.7048 1.1691
JHU-022 GDSC1 6.5135 12.9131 1.6869 12.9719
DOK GDSC1 7.0351 11.7951 2.531 6.6155
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 1.8583 3.7507 1.8451 27.9324
BC-3C CTRP2 2.0924 6.6712 1.5454 28.2014
CAL-29 GDSC1; CTRP2 2.2948 5.7412 2.031 25.8878
JMSU-1 CTRP2 2.2994 4.8834 2.2059 25.2669
U-BLC1 CTRP2 2.3316 4.9238 2.2343 25.0653
RT-4 GDSC1; CTRP2 2.3811 9.2612 0.869 29.4952
UM-UC-3 GDSC1; CTRP2 2.4036 6.6973 1.8754 26.0947
5637 GDSC1; CTRP2 2.7251 7.5459 1.9242 24.9526
SW1710 GDSC1; CTRP2 3.0066 7.185 2.3602 22.5501
253J-BV CTRP2 3.5331 6.1542 3.273 17.6439
SCaBER CTRP2 3.5656 7.5581 2.8153 19.2575
VM-CUB-1 CTRP2 3.5987 5.7547 3.4485 16.8133
RT-112 GDSC1; CTRP2 3.7907 8.6691 2.5805 19.5413
KMBC-2 CTRP2 4.0822 7.3927 3.428 15.4846
UM-UC-1 CTRP2 4.1274 7.3878 3.4775 15.1697
BFTC-905 GDSC1; CTRP2 4.4402 6.1073 4.2762 11.2631
647V GDSC1; CTRP2 4.4885 8.9432 3.1571 15.4985
TCCSUP GDSC1; CTRP2 4.7364 9.0913 3.3294 14.2024
J82 GDSC1; CTRP2 5.1769 6.7527 4.8413 7.0267
HT-1197 GDSC1; CTRP2 5.3257 8.6711 4.0928 9.7039
HT-1376 GDSC1; CTRP2 5.7443 7.507 5.0501 4.7972
SW780 GDSC1 6.132 7.6196 3.8297 0.5646
639V GDSC1; CTRP2 6.1517 8.7285 4.7906 5.0666
KU-19-19 GDSC1; CTRP2 6.3953 7.8581 5.4108 2.0574
T24 GDSC1; CTRP2 7.7109 17.2025 1.786 14.3293
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVMIU GDSC1 0.4615 6.0923 -0.479 48.8607
BPH-1 GDSC1 0.7933 5.9567 -0.0727 45.9319
Ca Ski GDSC1 1.1091 6.7948 -0.071 43.6459
SW954 GDSC1 1.1357 5.1833 0.5765 41.9582
PA-1 GDSC1 1.2039 4.4708 0.8774 40.4437
ACC-OV7 GDSC1 1.5388 7.7095 -0.0206 40.7805
JAR GDSC1 2.2109 6.0578 1.3892 31.3758
NEC8 GDSC1 2.2414 4.4174 2.0246 27.4043
C-33 A GDSC1 2.3547 7.3579 0.9625 32.6566
ME-180 GDSC1 2.7704 6.8108 1.6291 26.9374
SW962 GDSC1 3.0442 6.9961 1.8129 24.4299
HEY GDSC1 3.1648 8.5986 1.1564 27.6135
KGN GDSC1 3.2952 11.7868 -0.2972 32.9665
OMC-1 [Human cervical carcinoma] GDSC1 3.6105 7.7095 2.0039 20.5679
DSH1 GDSC1 3.9228 6.071 3.0959 11.2137
JHOS-3 GDSC1 3.9835 11.82 0.2872 28.1464
CAL-39 GDSC1 3.9978 6.3323 3.0353 11.3762
LB831-BLC GDSC1 4.0334 8.7558 1.8602 19.7527
PEO1 GDSC1 4.2477 14.7116 -0.9349 31.4065
OVCA420 GDSC1 4.3498 5.3803 3.8158 3.8922
OV17R GDSC1 4.3548 17.7642 -2.3718 34.5501
SiSo GDSC1 4.4862 11.7403 0.7487 24.2501
NCC-IT GDSC1 4.6781 5.8609 3.8252 2.7999
HT-3 GDSC1 4.7917 10.1969 1.7662 17.5503
HEC-1 GDSC1 4.8764 6.504 3.6512 3.5865
DoTc2 4510 GDSC1 5.0013 10.9048 1.5781 17.9987
C-4-I GDSC1 5.1621 7.8102 3.2186 6.0784
UWB1.289 GDSC1 5.2927 12.1569 1.1812 19.3192
NT2-D1 GDSC1 5.3361 11.5566 1.5111 17.3192
SW756 GDSC1 5.4563 8.0341 3.3045 4.7197
OVCA433 GDSC1 5.504 14.1779 0.3411 22.7672
HeLa GDSC1; CTRP2 5.5974 5.8988 5.5872 3.0124
MS751 GDSC1 5.6137 9.018 2.9434 6.939
SKG-IIIa GDSC1 5.9737 7.6269 3.7596 0.9927
SiHa GDSC1 6.1825 7.6883 3.8246 0.5491
JEG-3 GDSC1 6.1846 7.7573 3.7998 0.6395
SKN GDSC1 7.2707 9.1841 3.7037 0.3622
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6062).
2 A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 2006 May 19;125(4):733-47.