Details of the Drug

General Information of Drug (ID: DM3KN2Q)

Drug Name
GI-270384X
Synonyms 270384
Indication
Disease Entry ICD 11 Status REF
Inflammatory bowel disease DD72 Terminated [1]
Cross-matching ID
PubChem CID
168312750
TTD ID
D0RR4T

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
E-selectin (SELE) TTAU4D6 LYAM2_HUMAN Modulator [1]
Intercellular adhesion molecule ICAM-1 (ICAM1) TTCT6F7 ICAM1_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Inflammatory bowel disease
ICD Disease Classification DD72
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Intercellular adhesion molecule ICAM-1 (ICAM1) DTT ICAM1 5.21E-01 0.38 0.32
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Inhibition of endothelial cell adhesion molecule expression improves colonic hyperalgaesia. Neurogastroenterol Motil. 2009 Feb;21(2):189-96.