Details of the Drug

General Information of Drug (ID: DM3PC0J)

Drug Name

N-8295

Synonyms

Universal flu vaccine; M2e-ISS; NP-ISS; ISS vaccine (influenza), Dynavax; M2e/NP-ISS; Influenza vaccine (immunostimulatory sequence-based), Dynavax; Influenza vaccine (ND-ISS-based), Dynavax

Indication

Disease Entry	ICD 11	Status	REF
Influenza virus infection	1E30-1E32	Phase 1	[1]
------------------------------------------------------------------------------------

Drug Type

Vaccine

Cross-matching ID

TTD ID: D00CQL

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Toll-like receptor 9 (TLR9)	TTSHG0T	TLR9_HUMAN	Not Available	[2]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Influenza virus infection

ICD Disease Classification

1E30-1E32

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Toll-like receptor 9 (TLR9)	DTT	TLR9	2.58E-01	-0.06	-0.17

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Clinical pipeline report, company report or official report of Dynavax Technologies Corp.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019871)