Drug Name |
M2698
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Synonyms |
HXAUJHZZPCBFPN-QGZVFWFLSA-N; 1379545-95-5; SCHEMBL15262358; EX-A1187; AKOS030627134; M2698(MSC-2363318A) |
Indication |
Disease Entry |
ICD 11 |
Status |
REF |
Solid tumour/cancer |
2A00-2F9Z
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Phase 1 |
[1] |
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Structure |
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3D MOL
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2D MOL
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#Ro5 Violations (Lipinski): 0 |
Molecular Weight (mw) |
449.9 |
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Logarithm of the Partition Coefficient (xlogp) |
3.9 |
Rotatable Bond Count (rotbonds) |
6 |
Hydrogen Bond Donor Count (hbonddonor) |
2 |
Hydrogen Bond Acceptor Count (hbondacc) |
8 |
Chemical Identifiers |
- Formula
- C21H19ClF3N5O
- IUPAC Name
4-[[(1S)-2-(azetidin-1-yl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl]amino]quinazoline-8-carboxamide
- Canonical SMILES
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C1CN(C1)C[C@H](C2=CC(=C(C=C2)Cl)C(F)(F)F)NC3=NC=NC4=C3C=CC=C4C(=O)N
- InChI
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InChI=1S/C21H19ClF3N5O/c22-16-6-5-12(9-15(16)21(23,24)25)17(10-30-7-2-8-30)29-20-14-4-1-3-13(19(26)31)18(14)27-11-28-20/h1,3-6,9,11,17H,2,7-8,10H2,(H2,26,31)(H,27,28,29)/t17-/m1/s1
- InChIKey
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HXAUJHZZPCBFPN-QGZVFWFLSA-N
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Cross-matching ID |
- PubChem CID
- 89808643
- CAS Number
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- UNII
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- DrugBank ID
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- TTD ID
- D06HYF
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Combinatorial Drugs (CBD) |
Click to Jump to the Detailed CBD Information of This Drug
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