Details of the Drug

General Information of Drug (ID: DM3PZXN)

Drug Name
Taliglucerase alfa
Synonyms Elelyso (TN)
Indication
Disease Entry ICD 11 Status REF
Metabolic disorder 5C50-5D2Z Approved [1]
Affected Organisms
Humans and other mammals
ATC Code
A16AB11: Taliglucerase alfa
A16AB: Enzymes
A16A: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A: ALIMENTARY TRACT AND METABOLISM
ADMET Property
Clearance
The sytemic clearance of drug is 30 L/h []
Half-life
The concentration or amount of drug in body reduced by one-half in 18.9 - 28.7 minutes [2]
Vd
The volume of distribution (Vd) of drug is 7.30-11.7 L []
Cross-matching ID
UNII
N69L6LM4QU
DrugBank ID
DB08876
TTD ID
D0G6HA

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucosylceramidase (GBA) TT1B5PU GLCM_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7444).
2 Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
3 Nat Rev Drug Discov. 2013 Feb;12(2):87-90.