Details of the Drug

General Information of Drug (ID: DM3WDZ5)

Drug Name
MK-1775
Synonyms
MK-1775; 955365-80-7; Adavosertib; MK1775; MK 1775; UNII-K2T6HJX3I3; AZD 1775; AZD-1775; AZD1775; 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one; K2T6HJX3I3; 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one; 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one; AK-99219
Indication
Disease Entry ICD 11 Status REF
Ovarian cancer 2C73 Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 500.6
Logarithm of the Partition Coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 9
Chemical Identifiers
Formula
C27H32N8O2
IUPAC Name
1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
Canonical SMILES
CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
InChI
InChI=1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-17H2,2-4H3,(H,28,29,31)
InChIKey
BKWJAKQVGHWELA-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24856436
ChEBI ID
CHEBI:91414
CAS Number
955365-80-7
UNII
K2T6HJX3I3
DrugBank ID
DB11740
TTD ID
D02KKA
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Wee1-like protein kinase (WEE1) TTJFOAL WEE1_HUMAN Inhibitor [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Drug Response [4]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Post-Translational Modifications [4]
Wee1-like protein kinase OTOHEU0N WEE1_HUMAN Post-Translational Modifications [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

ICD Disease Classification 02 Neoplasm
Disease Class ICD-11: 2C82 Prostate cancer
The Studied Tissue Ovarian tissue
The Studied Disease Ovarian cancer [ICD-11:2C82]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Wee1-like protein kinase (WEE1) DTT WEE1 7.06E-07 1.06 4.21
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 1.0573 5.2049 0.1671 27.3964
EW-1 GDSC2 -1.7554 0.8669 -1.7888 50.9226
SK-ES-1 GDSC2; CTRP2 -1.6152 1.4294 -1.6377 44.4204
EW-12 GDSC2 -1.4446 1.7659 -1.5525 47.9721
ES1 GDSC2 -1.2986 2.5488 -1.5325 46.7686
EW-7 GDSC2 -1.0976 4.9522 -2.0275 45.9472
HuO9 GDSC2 -1.067 1.8735 -1.1641 44.3328
ES5 GDSC2 -0.7871 3.3323 -1.1652 42.4172
SK-PN-DW GDSC2 -0.6631 1.6347 -0.7084 40.185
ES8 GDSC2 -0.4913 1.4001 -0.5116 38.3615
A-673 GDSC2; CTRP2 -0.4269 5.2284 -0.9778 37.9675
EW-18 GDSC2 -0.05 5.2245 -1.0087 37.6271
NY GDSC2 -0.0491 4.4195 -0.7059 36.6069
CAL-72 GDSC2 0.0305 3.8634 -0.4313 35.1226
U2OS GDSC2; CTRP2; CTRP1 0.0615 4.7128 -0.3045 34.4088
SK-N-MC CTRP2 0.1717 1.9526 0.1677 32.4759
NOS-1 [Human HNSCC] GDSC2 0.2525 5.9263 -0.9761 35.9585
CAL-78 GDSC2; CTRP2 0.2694 5.2515 -0.2247 33.3824
MHH-ES-1 GDSC2 0.5544 3.4847 0.2556 29.295
SaOS-2 GDSC2; CTRP2 0.6717 3.2104 0.6203 29.3038
TC71 CTRP2 0.7714 2.1753 0.7698 28.4727
ES7 GDSC2 1.0358 4.0743 0.5875 25.3187
HuO-3N1 GDSC2 1.131 4.6958 0.4535 25.6035
EW-22 GDSC2 1.1511 5.9231 -0.047 28.0203
EW-16 GDSC2 1.1531 5.7862 0.0156 27.7141
CADO-ES1 GDSC2 1.4536 3.8298 1.1247 20.5181
TC-71 GDSC2 1.4887 3.8527 1.1548 20.1956
MG-63 GDSC2; CTRP2 1.7223 5.8763 1.1618 24.1111
HOS GDSC2; CTRP2 1.9979 5.1706 1.6843 21.3948
EW-3 GDSC2 2.2127 6.6404 0.667 20.0911
CHSA8926 GDSC2 2.4201 13.3556 -2.465 31.8558
ES6 GDSC2 2.4811 9.6532 -0.5691 25.2518
EW-11 GDSC2 2.6498 12.0088 -1.5936 28.5631
CHSA0108 GDSC2 2.9602 9.1893 0.0816 20.6467
CHSA0011 GDSC2 3.0723 8.8928 0.3259 19.0374
G-292 clone A141B1 GDSC2; CTRP2 3.5894 8.2597 2.1069 15.4519
SW1353 CTRP2 3.7688 9.599 1.6329 16.9083
SJSA-1 GDSC2; CTRP2 3.8019 9.7222 1.6036 16.9462
EW-13 GDSC2 4.2188 6.775 2.2735 4.4375
H-EMC-SS GDSC2 4.5408 10.7347 0.5758 13.6179
U-CH2 GDSC2 4.6274 10.6819 0.6651 12.9261
EW-24 GDSC2 4.9462 11.5028 0.4934 13.0922
ES4 GDSC2 5.5936 15.9068 -1.1924 19.2649
Hs 822.T CTRP2 6.2718 7.3053 4.7014 0.2225
Hs 888.T CTRP2 6.5049 17.7695 -0.1458 17.8072
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -4.3731 2.8952 -4.7363 60.2543
MEC1 CTRP2 -0.7371 1.3625 -0.7416 38.5316
JM1 GDSC2; CTRP2 -3.0196 -1.2204 -3.0197 53.7229
Mino CTRP2 -14.7173 20.1107 -21.9165 68.13
Ri-1 CTRP2 -8.3308 3.7954 -9.2312 71.7881
KE-37 GDSC2; CTRP2 -6.2903 -4.3888 -6.2903 75.4314
EM-2 GDSC2; CTRP2 -5.3476 6.7645 -6.8092 61.2191
ATN-1 GDSC2 -4.086 -2.752 -4.086 74.2494
SEM CTRP2 -3.4894 -1.4616 -3.4896 56.8486
Mono-Mac-1 CTRP2 -3.3639 1.8634 -3.4989 55.5148
JURL-MK1 GDSC2; CTRP2 -3.3511 -1.0125 -3.3519 55.9208
697 GDSC2; CTRP2 -3.2272 -0.8299 -3.2283 55.0951
JVM-2 GDSC2 -3.182 -0.4209 -3.1961 64.5605
JeKo-1 GDSC2; CTRP2 -3.1097 -1.9753 -3.1097 54.3241
NU-DUL-1 GDSC2; CTRP2; CTRP1 -3.0092 -1.4257 -3.0092 53.6985
P31/FUJ GDSC2; CTRP2 -3.0065 -1.012 -3.0068 53.6346
MOLM-16 GDSC2; CTRP1 -3.0035 -1.369 -3.0036 68.8506
A4/Fukuda GDSC2; CTRP2 -2.9608 -0.8452 -2.9613 53.3291
Pfeiffer CTRP2 -2.8827 -1.3993 -2.8827 52.8114
MHH-CALL-4 GDSC2; CTRP2 -2.8013 11.7876 -5.978 51.1612
MOLM-13 GDSC2 -2.7877 -1.558 -2.7877 61.3048
MOLT-16 GDSC2; CTRP2 -2.7046 -0.633 -2.7051 51.6237
SUP-B8 GDSC2 -2.6813 -0.7663 -2.6831 60.1599
EoL-1 GDSC2; CTRP2 -2.6769 -0.2186 -2.6791 51.4366
Hs 611.T CTRP2 -2.6211 -0.6343 -2.6215 51.0682
Kasumi-2 CTRP2 -2.5763 0.8399 -2.5992 50.7577
BALL-1 GDSC2 -2.5608 -1.521 -2.5608 59.033
Karpas-231 GDSC2 -2.5606 -1.2157 -2.5607 59.0248
MOTN-1 CTRP2 -2.5275 -0.7852 -2.5276 50.445
Granta-519 GDSC2; CTRP2 -2.5169 1.5937 -2.5815 50.3613
SU-DHL-5 GDSC2; CTRP1 -2.5002 -0.7885 -2.5003 64.5642
M-07e CTRP2 -2.4917 -0.5618 -2.4921 50.2068
KMS-26 CTRP2 -2.4417 -1.9129 -2.4417 49.8734
KMS-20 CTRP2 -2.432 6.9861 -3.717 49.8655
MOLT-3 CTRP2 -2.4254 -1.8639 -2.4254 49.7648
RPMI-8402 GDSC2; CTRP2 -2.3785 -1.3291 -2.3785 49.4526
EB1 CTRP2 -2.3622 1.2844 -2.4 49.3578
BE-13 GDSC2 -2.3467 -0.4798 -2.3488 56.8418
BC-3 GDSC2 -2.332 -1.1453 -2.332 56.7356
SUP-M2 GDSC2; CTRP2 -2.2538 -0.7524 -2.2539 48.6219
JVM-3 GDSC2; CTRP2 -2.2402 -0.2143 -2.2408 48.5316
EJM GDSC2; CTRP2; CTRP1 -2.2394 1.0924 -2.2638 48.5953
KE-97 CTRP2; CTRP1 -2.212 -0.7669 -2.212 48.3929
L-540 GDSC2; CTRP2 -2.2086 0.3337 -2.213 48.3257
CCRF-CEM GDSC2 -2.2016 -1.2522 -2.2016 55.4286
BONNA-12 GDSC2 -2.1375 0.9662 -2.1955 54.5075
Peer CTRP2 -2.1259 0.2166 -2.1285 47.7737
HC-1 GDSC2 -2.115 -0.0045 -2.1217 54.508
HuNS1 CTRP2 -2.0718 0.8306 -2.0839 47.4272
KY821 GDSC2 -2.0707 0.1456 -2.0802 54.0552
SU-DHL-8 GDSC2; CTRP2 -2.0453 -0.7598 -2.0453 47.2328
CESS GDSC2 -2.0077 1.5051 -2.1179 53.1861
SET-2 CTRP2 -1.9989 1.4684 -2.0349 46.9769
ARH-77 GDSC2 -1.9562 -0.8989 -1.9562 52.9658
BV-173 GDSC2; CTRP2 -1.9331 1.8078 -1.9888 46.5712
PF-382 GDSC2; CTRP2 -1.9314 0.5398 -1.936 46.4832
OCI-Ly3 CTRP2 -1.9209 0.1883 -1.9222 46.4067
OCI-Ly7 GDSC2 -1.9174 -0.8823 -1.9174 52.5767
Hs 445 GDSC2 -1.9156 2.6141 -2.2174 52.1394
P32/ISH GDSC2 -1.9084 -0.8579 -1.9085 52.4872
Loucy GDSC2 -1.8907 -0.1401 -1.893 52.3001
QIMR-WIL GDSC2 -1.8656 -0.1409 -1.8677 52.0502
PL-21 GDSC2 -1.8606 -0.2478 -1.8619 52.0028
PL21 CTRP2; CTRP1 -1.8446 1.3179 -1.8682 45.9928
SKM-1 GDSC2; CTRP2; CTRP1 -1.8438 -0.3779 -1.8438 45.9421
JSC-1 GDSC2 -1.8285 0.5386 -1.8465 51.6526
Farage GDSC2 -1.8074 1.0421 -1.8561 51.4112
Namalwa GDSC2; CTRP2 -1.7946 0.3334 -1.7963 45.5666
DEL GDSC2; CTRP2 -1.7606 -1.4718 -1.7606 45.3356
SU-DHL-4 GDSC2; CTRP2; CTRP1 -1.7363 -0.7563 -1.7363 45.2265
ST486 GDSC2; CTRP2 -1.7349 0.3833 -1.7366 45.1689
SUP-T1 GDSC2; CTRP2 -1.7268 4.0934 -2.1089 45.6596
NOMO-1 GDSC2; CTRP2; CTRP1 -1.7156 -0.6752 -1.7156 45.0893
L-428 GDSC2; CTRP2 -1.7125 1.6471 -1.7489 45.0915
OCI-Ly19 GDSC2; CTRP2 -1.7099 2.4429 -1.8131 45.1879
BC-1 GDSC2 -1.658 0.329 -1.6653 49.9745
RPMI-8866 GDSC2 -1.6576 -0.2497 -1.6581 49.9701
CTB-1 GDSC2 -1.6322 0.6811 -1.6511 49.72
MEG-01 GDSC2 -1.6303 0.2198 -1.635 49.6979
RCH-ACV GDSC2; CTRP2 -1.6194 0.5176 -1.6214 44.4006
Ku812 GDSC2; CTRP2; CTRP1 -1.5839 1.3875 -1.6037 44.2605
Karpas-299 GDSC2; CTRP2 -1.5679 0.3622 -1.5689 44.0549
TK [Human B-cell lymphoma] GDSC2 -1.5632 0.323 -1.569 49.029
ML-2 GDSC2 -1.5524 -0.2621 -1.5527 48.9145
NALM-6 GDSC2; CTRP2 -1.5371 0.9814 -1.5444 43.8664
GA-10 GDSC2; CTRP2 -1.5327 -0.124 -1.5328 43.8178
WIL2 NS GDSC2 -1.5305 0.4742 -1.5394 48.706
IM-9 GDSC2 -1.5248 -0.0253 -1.5259 48.6393
LC4-1 GDSC2 -1.5147 0.7852 -1.5351 48.5612
BL-41 GDSC2 -1.4913 -0.2524 -1.4916 48.3022
MLMA GDSC2 -1.4658 3.5519 -1.9677 48.4423
RPMI-6666 GDSC2; CTRP2 -1.4604 1.3415 -1.4758 43.3766
CRO-AP2 GDSC2 -1.4553 0.8951 -1.4797 47.9794
CTV-1 GDSC2 -1.4486 0.2235 -1.4515 47.8793
P12-Ichikawa GDSC2 -1.3989 -0.0563 -1.3995 47.3758
Karpas-45 GDSC2 -1.3953 0.6419 -1.4067 47.3631
KMS-11 GDSC2; CTRP2; CTRP1 -1.3944 0.7795 -1.3973 42.9597
SU-DHL-16 GDSC2 -1.3908 -0.0758 -1.3912 47.2939
MV4-11 GDSC2; CTRP2 -1.3473 -0.0507 -1.3473 42.5825
DB GDSC2; CTRP2 -1.346 1.3802 -1.3603 42.6135
L-1236 GDSC2 -1.3449 3.1818 -1.7335 47.3513
CML-T1 GDSC2; CTRP2 -1.3392 0.4883 -1.34 42.5307
DND-41 GDSC2 -1.3186 0.6361 -1.3282 46.5942
VAL GDSC2 -1.3112 0.8191 -1.3274 46.5356
WSU-NHL GDSC2 -1.3093 0.2571 -1.3114 46.4814
NK-92MI GDSC2 -1.3031 -0.0073 -1.3036 46.4142
SU-DHL-1 GDSC2; CTRP2 -1.263 1.1032 -1.2691 42.0388
EB2 GDSC2 -1.2507 1.7921 -1.3491 46.1088
WSU-DLCL2 GDSC2; CTRP1 -1.2289 -0.43 -1.2289 53.7328
U-937 CTRP2; CTRP1 -1.2177 0.4764 -1.2181 41.7764
SU-DHL-10 GDSC2 -1.2053 -0.2171 -1.2054 45.4318
OCI-M1 GDSC2; CTRP2 -1.1868 1.5511 -1.2034 41.5614
KMOE-2 GDSC2 -1.1617 0.8374 -1.1748 45.0378
MOLT-13 GDSC2; CTRP2 -1.1433 0.5276 -1.1438 41.2248
KMS-12-BM GDSC2; CTRP2 -1.1319 1.0137 -1.1354 41.1585
Jiyoye GDSC2 -1.1291 0.4196 -1.1317 44.6766
SCC-3 GDSC2 -1.1048 1.5189 -1.162 44.5974
HAL-01 GDSC2 -1.1022 0.5428 -1.1063 44.4127
SUP-HD1 GDSC2; CTRP2 -1.0887 1.4301 -1.0995 40.8924
GDM-1 GDSC2; CTRP2; CTRP1 -1.064 1.4355 -1.0744 40.7838
SIG-M5 GDSC2; CTRP2 -1.0363 0.2588 -1.0363 40.5103
Kasumi-1 GDSC2; CTRP2 -1.0323 1.8942 -1.0598 40.5652
KOPN-8 GDSC2 -1.0315 0.2429 -1.0321 43.6894
LAMA-84 GDSC2; CTRP2 -1.0223 1.6087 -1.0373 40.4627
HPB-ALL CTRP2 -1.0184 1.5338 -1.0309 40.4296
ALL-PO GDSC2 -0.9823 1.3874 -1.0214 43.3345
TUR GDSC2 -0.9702 0.716 -0.9759 43.0956
KMS-28BM CTRP2 -0.9643 7.3471 -2.2599 42.4831
MOLT-4 GDSC2 -0.9637 1.4024 -1.0032 43.1514
HT GDSC2; CTRP2; CTRP1 -0.9568 0.4705 -0.9569 40.0392
H9 GDSC2 -0.9344 0.4765 -0.9361 42.7202
U-698-M GDSC2 -0.9187 0.1803 -0.9189 42.5561
RS4;11 GDSC2; CTRP2 -0.9152 1.4878 -0.9246 39.733
KM-H2 GDSC2; CTRP2 -0.9139 2.2922 -0.9623 39.8379
Jurkat GDSC2; CTRP2 -0.9122 1.7844 -0.9312 39.7419
Ki-JK CTRP2 -0.8942 3.2733 -1.053 39.9986
DG-75 GDSC2 -0.8914 0.653 -0.8949 42.2965
THP-1 GDSC2; CTRP2; CTRP1 -0.8721 0.4589 -0.8722 39.4751
BCP-1 CTRP2 -0.8449 1.7796 -0.8621 39.2889
OPM-2 GDSC2; CTRP2 -0.8432 1.5853 -0.8539 39.2577
MOLP-8 GDSC2; CTRP2 -0.8395 3.6746 -1.0614 39.7984
KMS-34 CTRP2 -0.8215 -0.0398 -0.8215 39.0793
MOLM-6 CTRP2 -0.8173 2.9958 -0.9318 39.3799
KO52 CTRP2 -0.8155 1.3559 -0.8207 39.0563
BL-70 CTRP2; CTRP1 -0.7878 0.0542 -0.7878 38.9138
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -0.7805 3.1061 -0.9072 39.1705
NU-DHL-1 CTRP2 -0.7675 3.9411 -1.0347 39.4433
SU-DHL-6 GDSC2; CTRP2 -0.7633 0.9265 -0.7641 49.692
MY-M12 GDSC2 -0.7558 0.3209 -0.7561 40.9219
OCI-Ly10 CTRP2; CTRP1 -0.7252 3.6672 -0.9353 39.0846
Ramos.2G6.4C10 GDSC2 -0.7146 0.3934 -0.715 40.509
HDLM-2 GDSC2; CTRP2 -0.7067 4.1198 -1.0058 39.13
NKM-1 GDSC2 -0.7067 0.3524 -0.7069 40.4286
NB4 GDSC2; CTRP2 -0.6524 -0.1818 -0.6524 37.9527
CA46 GDSC2; CTRP2 -0.6518 3.8573 -0.8928 38.63
MOLP-2 CTRP2 -0.63 3.6765 -0.8356 38.3955
HD-MY-Z CTRP2 -0.6067 2.708 -0.6764 37.863
OCI-AML-3 GDSC2; CTRP2; CTRP1 -0.6037 0.7838 -0.6039 37.6892
OCI-AML-2 GDSC2; CTRP2 -0.5969 0.5108 -0.5969 37.583
MHH-PREB-1 GDSC2 -0.5945 0.6792 -0.5959 39.3086
ALL-SIL GDSC2 -0.5795 1.3018 -0.5973 39.2336
P3HR-1 CTRP2; CTRP1 -0.5671 1.4175 -0.5706 37.4563
SK-MM-2 GDSC2; CTRP2 -0.5551 2.8226 -0.6336 37.5472
AMO1 GDSC2; CTRP2; CTRP1 -0.5384 2.4093 -0.5791 37.3825
GR-ST GDSC2 -0.5372 3.1371 -0.8406 39.8881
MC116 GDSC2; CTRP2; CTRP1 -0.5252 0.0123 -0.5252 37.1659
NCO2 CTRP2 -0.5085 2.0075 -0.5263 37.0516
L-363 GDSC2; CTRP2 -0.4944 0.6747 -0.4944 36.9001
YT GDSC2 -0.4921 0.6311 -0.4927 38.277
P30/OHK GDSC2 -0.4753 1.6331 -0.5113 38.2722
HuT 78 CTRP2 -0.4642 2.6867 -0.5245 36.8892
VL51 GDSC2 -0.4425 2.2663 -0.5537 38.2667
MHH-CALL-2 GDSC2 -0.3968 1.9126 -0.4562 37.5924
Reh GDSC2; CTRP2 -0.3907 1.1365 -0.3912 36.2111
DoHH2 GDSC2 -0.382 0.505 -0.3821 37.1699
MM1.S GDSC2; CTRP2 -0.3514 1.3465 -0.3529 35.9525
Karpas-1106P GDSC2 -0.3448 2.8366 -0.5584 37.7208
KCL-22 GDSC2; CTRP2 -0.3186 1.6293 -0.3227 35.7426
RC-K8 GDSC2 -0.2774 3.907 -0.7802 38.1443
OCI-AML-5 GDSC2; CTRP2 -0.2553 1.088 -0.2555 35.3079
F-36P CTRP2 -0.2163 1.8624 -0.2235 35.0714
JJN-3 GDSC2; CTRP2 -0.188 1.2887 -0.1886 34.8611
A3/Kawakami GDSC2; CTRP2 -0.1823 1.7694 -0.1873 34.8376
U266B1 GDSC2; CTRP2 -0.156 2.6926 -0.2021 34.7964
K-562 GDSC2; CTRP2 -0.1122 1.3525 -0.1128 34.3558
AML-193 CTRP2 -0.1019 5.4585 -0.6903 36.0204
SUP-B15 GDSC2; CTRP2 -0.0881 1.5508 -0.0896 34.1984
KHM-1B CTRP2 -0.0864 3.5824 -0.2343 34.6559
Mono-Mac-6 GDSC2; CTRP2 -0.0622 12.0852 -3.2936 40.6563
KMS-18 CTRP2 -0.0509 1.5309 -0.0521 33.9493
Daudi GDSC2; CTRP2 -0.0317 1.7069 -0.0343 33.8266
HEL 92.1.7 CTRP2 -0.0238 1.1531 -0.0239 33.7654
KYO-1 CTRP2 0.1228 1.4982 0.1224 32.7897
Karpas-422 GDSC2; CTRP2 0.1798 1.8121 0.1777 32.4157
HEL GDSC2; CTRP2 0.1855 2.4091 0.169 32.4259
KG-1 GDSC2 0.2028 3.2815 -0.0711 32.6359
TF-1 CTRP2 0.2864 1.9216 0.2839 31.7067
LP-1 GDSC2; CTRP2; CTRP1 0.3372 5.6518 -0.2673 33.3374
KMS-27 CTRP2 0.3679 1.9865 0.3653 31.1642
CMK CTRP2 0.4067 1.5726 0.4066 30.8974
SUP-T11 CTRP2 0.5119 4.3598 0.2666 31.0125
RL GDSC2; CTRP2 0.5206 1.3271 0.5206 30.1383
HL-60 GDSC2; CTRP2 0.548 2.1262 0.5453 29.9645
SR GDSC2; CTRP2 0.5546 1.8972 0.5538 29.9143
Ci-1 CTRP2 0.5619 1.3538 0.5619 29.863
EHEB CTRP2 0.6056 5.0689 0.1935 30.9402
Raji GDSC2; CTRP2 0.7015 2.1579 0.6996 28.9394
ME1 GDSC2 0.9139 4.9624 0.1168 28.29
ROS-50 GDSC2 1.0248 5.0544 0.1957 27.3991
RPMI-8226 GDSC2; CTRP2; CTRP1 1.2665 3.8296 1.1795 25.5353
ME1 CTRP2 1.4262 5.8566 0.8475 26.1233
MN-60 GDSC2 1.5357 5.332 0.6075 23.0485
MHH-CALL-3 CTRP2 1.7221 11.0758 -1.0469 31.0664
NCI-H929 GDSC2; CTRP2 1.7718 5.3609 1.3817 23.171
HH [Human lymphoma] GDSC2 3.2971 6.1153 1.9045 9.0415
Toledo CTRP2 5.6086 12.9434 1.5547 13.407
Karpas-620 GDSC2; CTRP2 7.2619 9.1127 4.4308 0.3896
KMM-1 CTRP2 7.3898 13.6486 2.5048 6.8631
REC-1 CTRP2 8.2541 9.9289 4.5104 0.0748
⏷ Show the Full List of 219 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 -0.5448 7.1954 -1.7532 40.04
TE8 CTRP2 -0.3792 1.3356 -0.3807 36.1374
EC-GI-10 GDSC2; CTRP2 -0.9117 2.6792 -0.995 39.9187
TE-8 GDSC2 -0.7935 3.0534 -1.099 42.2869
KYSE-140 GDSC2; CTRP2; CTRP1 -0.5509 1.8244 -0.5629 37.3757
T.T GDSC2 -0.1027 3.451 -0.4515 35.929
TE-11 GDSC2; CTRP2 -0.033 3.6364 -0.1855 34.317
KYSE-270 GDSC2 -0.0298 2.849 -0.2185 34.5314
TE-15 GDSC2 0.1487 5.9382 -1.0894 36.8433
OE21 GDSC2; CTRP2 0.187 4.1779 -0.0477 33.1224
TE-10 GDSC2; CTRP2 0.2513 4.5204 -0.0532 32.9193
TE-14 CTRP2 0.5125 3.1237 0.4612 30.3638
TE-4 GDSC2; CTRP2 0.5414 2.7981 0.5161 30.0841
KYSE-410 GDSC2; CTRP2; CTRP1 0.8423 5.3859 0.3639 29.6745
KYSE-70 GDSC2; CTRP2 1.0382 3.7231 0.9495 26.9897
TE-9 GDSC2; CTRP2 1.2162 5.0666 0.8605 26.7294
KYSE-450 GDSC2; CTRP2; CTRP1 1.2979 3.3835 1.2624 25.1511
OE33 GDSC2; CTRP2 1.3192 6.445 0.5258 27.5616
KYSE-150 GDSC2; CTRP2 1.9049 5.9223 1.3438 22.909
TE-6 GDSC2; CTRP2 1.9475 5.8199 1.4251 22.4871
KYSE-180 GDSC2; CTRP2 1.9952 7.5226 0.8205 24.5364
TE-1 GDSC2; CTRP2 2.2227 6.8172 1.3489 21.9702
OE19 GDSC2; CTRP2 2.49 6.1232 1.9023 19.1426
TE-5 GDSC2; CTRP2 2.671 9.0364 0.8399 22.615
KYSE-520 GDSC2; CTRP2 2.9838 7.8313 1.7043 18.5584
KYSE-510 GDSC2; CTRP2 3.4507 6.6577 2.7012 13.4299
KYSE-30 CTRP2 3.8618 8.0172 2.4856 13.2705
COLO 680N GDSC2; CTRP2 4.6074 9.7115 2.3374 12.2221
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.5644 9.3774 1.5478 17.7221
Panc 03.27 GDSC2; CTRP2; CTRP1 -2.0279 0.7165 -2.0364 47.1815
PaTu 8988s CTRP2 -1.6635 4.8324 -2.2193 45.4738
PaTu 8988t GDSC2; CTRP2 -0.7116 1.5225 -0.7187 38.3702
SUIT-2 GDSC2; CTRP1 -0.1076 5.2457 -0.6315 40.9594
BxPC-3 GDSC2; CTRP2 0.1009 5.1042 -0.367 34.3916
DAN-G GDSC2; CTRP2 0.4772 4.4894 0.1999 31.346
HPAC GDSC2; CTRP2 0.4789 4.2054 0.2634 31.1328
KP-4 GDSC2; CTRP2 0.5864 2.6167 0.5717 29.749
PSN1 GDSC2; CTRP2 0.8682 3.3555 0.813 28.0078
HuP-T4 GDSC2; CTRP2; CTRP1 0.8738 4.9061 0.5324 29.0106
PL4 GDSC2 0.9744 4.9139 0.2003 24.4135
MIA PaCa-2 GDSC2; CTRP2 1.1995 4.1982 1.0454 26.1406
KP-1N GDSC2 1.2328 5.2226 0.3423 22.7629
Panc 02.03 GDSC2; CTRP2 1.2626 5.1791 0.8796 26.5171
Panc 08.13 GDSC2; CTRP2 1.6426 5.7892 1.1048 24.5551
SW1990 GDSC2; CTRP2 2.0084 8.7021 0.3241 26.208
HuP-T3 GDSC2; CTRP2 2.0491 7.4477 0.9082 24.07
Panc 10.05 GDSC2; CTRP2 2.1117 8.797 0.3868 25.708
KP-2 GDSC2; CTRP2 2.1923 6.486 1.4465 21.6952
KP-3 GDSC2; CTRP2; CTRP1 2.2439 9.046 0.4146 25.3145
PANC-1 CTRP2 2.467 6.2945 1.8132 19.543
Hs 766T GDSC2; CTRP2 2.685 9.4525 0.6603 23.2172
Capan-2 GDSC2; CTRP2; CTRP1 2.7522 8.9389 0.9724 21.9924
PK-59 CTRP2 2.7773 10.3169 0.3427 24.0722
YAPC GDSC2; CTRP2 2.8012 7.8789 1.4979 19.8289
PaTu 8902 GDSC2; CTRP2; CTRP1 2.8836 6.8967 2.0162 17.6934
Capan-1 GDSC2; CTRP2 2.8991 8.3873 1.3662 20.074
HPAF-II GDSC2; CTRP2 2.9729 10.7033 0.3459 23.563
MZ-PC-1 GDSC2 3.1509 7.678 0.9997 13.3043
QGP-1 GDSC2; CTRP2; CTRP1 3.2566 7.2753 2.2367 15.8477
SNU-213 CTRP2 3.2808 10.9296 0.5281 22.176
L3.3 CTRP2 3.2998 7.5429 2.1537 15.9855
PK-45H CTRP2 3.3866 10.4348 0.8678 20.7109
SU.86.86 GDSC2; CTRP2 3.4676 10.0525 1.1296 19.5505
TCC-Pan2 CTRP2 3.5289 8.3259 2.0167 15.9589
Panc 04.03 GDSC2; CTRP2 3.7192 9.0304 1.8622 16.1185
CFPAC-1 GDSC2; CTRP2 4.1481 11.7014 0.9423 18.68
AsPC-1 GDSC2; CTRP2 4.221 11.46 1.127 17.8337
Panc 05.04 CTRP2 4.4171 10.7444 1.6561 15.3715
SNU-410 CTRP2 7.3793 16.1177 1.3123 11.377
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 0.2707 10.1034 -2.0729 37.7377
M14 GDSC2 -1.7201 2.675 -2.0184 50.5062
COLO 741 CTRP2 -0.2457 16.8758 -5.7027 43.4318
G-mel GDSC2 -0.2086 2.5546 -0.3519 36.0935
A-388 GDSC2 -0.1824 3.5197 -0.5583 36.7958
DJM-1 GDSC2 0.0205 3.184 -0.2442 34.3788
RPMI-7951 GDSC2; CTRP2 0.031 5.8201 -0.6568 35.4494
CHL-1 GDSC2 0.0928 2.8417 -0.0836 33.2632
A-375 GDSC2; CTRP2; CTRP1 0.2561 3.4846 0.1483 32.3219
WM88 CTRP2 0.6417 5.2742 0.1749 30.8809
GAK GDSC2 0.6702 3.5718 0.3562 28.2274
HMCB CTRP2 0.7134 2.8613 0.6903 28.931
IGR-37 GDSC2; CTRP2 0.7544 3.7257 0.6456 28.9469
A2058 GDSC2; CTRP2 0.7587 1.9312 0.7583 28.5533
Hs 936.T CTRP2; CTRP1 0.8132 6.3602 0.0146 30.8916
IPC-298 GDSC2; CTRP2 0.8657 3.5193 0.7921 28.0869
MDA-MB-435S CTRP2 0.9135 4.1218 0.7505 28.0731
A-431 GDSC2 0.9149 5.0691 0.0742 28.4927
CJM [Human melanoma] CTRP2 1.2717 4.6154 1.0359 25.9439
IST-MEL1 GDSC2 1.321 6.5083 -0.1402 27.7293
WM1552C GDSC2 1.3692 5.4961 0.3647 25.0391
SH-4 GDSC2 1.3897 5.6044 0.3378 25.0925
WM983B CTRP2 1.4245 7.6536 0.1677 28.4261
SK-MEL-2 GDSC2; CTRP2 1.5188 4.1622 1.3968 23.9043
Hs 852.T CTRP2; CTRP1 1.5225 8.8402 -0.2283 29.4274
LOX-IMVI GDSC2; CTRP2 1.6108 5.5078 1.1611 24.4507
451Lu GDSC2 1.6474 4.957 0.8858 21.0423
LB2518-MEL GDSC2 1.6528 4.9693 0.8861 21.0177
CP50-MEL-B GDSC2 1.8096 4.0937 1.4114 17.3615
G-361 GDSC2; CTRP2; CTRP1 1.8688 6.9041 0.944 24.5315
Mel JuSo GDSC2; CTRP2 1.9462 6.8209 1.0542 23.8401
Hs 294T CTRP2 1.9911 8.1829 0.5345 25.5461
Hs 944.T CTRP2; CTRP1 2.0307 9.6988 -0.097 27.5636
SK-MEL-5 GDSC2; CTRP2; CTRP1 2.2476 6.6579 1.4433 21.6239
WM35 GDSC2 2.2502 5.7948 1.1086 17.4102
MZ-MEL-7 GDSC2 2.2842 7.5302 0.3008 21.8127
MeWo GDSC2; CTRP2 2.3923 6.5257 1.6442 20.3892
Hs 940.T GDSC2; CTRP2 2.4145 12.7922 -1.1922 29.5663
K029AX CTRP2 2.5955 8.1827 1.153 21.6718
SK-MEL-1 GDSC2; CTRP2; CTRP1 2.6554 9.81 0.4707 24.0197
HMV-II GDSC2 2.8283 10.0444 -0.459 23.6208
MZ-MEL-2 GDSC2 2.8692 8.1881 0.502 18.7431
WT2-iPS GDSC2; CTRP2 2.8729 9.0645 1.0266 21.4105
IGR-1 GDSC2; CTRP2 3.0307 9.9935 0.7415 22.0428
WM278 GDSC2 3.0503 9.966 -0.2291 21.8661
COLO 783 GDSC2 3.206 8.2031 0.784 16.1105
HT-144 GDSC2; CTRP2 3.7139 10.9775 0.9073 19.7919
SK-MEL-3 GDSC2; CTRP2 3.9655 8.3943 2.403 13.3634
Hs 938.T GDSC2 3.9765 7.7482 1.6278 8.9317
COLO 679 GDSC2 4.1516 9.6394 0.8252 13.2235
WM793 GDSC2; CTRP2 4.3405 10.1003 1.9083 14.5327
VMRC-MELG GDSC2 4.3801 10.3111 0.6652 13.5312
CP66-MEL GDSC2 4.4023 8.0037 1.8088 6.8384
LB373-MEL-D GDSC2 4.4054 8.913 1.3698 9.449
COLO 800 GDSC2; CTRP2 4.5884 14.3123 0.0252 20.9147
IGR-39 CTRP2 4.886 11.0541 1.9065 13.4047
COLO 829 GDSC2; CTRP2 4.9193 13.7767 0.5736 18.3743
MMAc-SF GDSC2 5.206 8.0104 2.2992 2.6348
Hs 688(A).T CTRP2 5.3549 8.273 3.681 5.159
A101D GDSC2; CTRP2 5.6277 11.6777 2.2004 10.8114
SK-MEL-30 GDSC2; CTRP2 5.642 10.2092 2.9415 7.7433
WM115 GDSC2; CTRP2 5.8683 15.0544 0.7083 16.0728
Mel Ho GDSC2; CTRP2 5.936 11.8449 2.3556 9.6452
Hs 839.T CTRP2 5.988 11.4962 2.5672 8.6984
Hs 895.T CTRP2 6.1845 14.7163 1.1227 14.0099
SK-MEL-28 GDSC2; CTRP2; CTRP1 6.5683 10.453 3.4921 4.1733
RVH-421 GDSC2; CTRP2 6.9134 12.7069 2.6366 7.0019
SK-MEL-24 GDSC2; CTRP2 7.0968 15.1012 1.6068 10.7131
UACC-257 GDSC2; CTRP2 7.4094 14.0784 2.3138 7.5694
WM266-4 CTRP2 7.8054 14.8345 2.2147 7.4193
WM1799 CTRP2 8.2401 20.2056 -0.0663 14.7829
SK-MEL-31 GDSC2; CTRP2 8.6335 18.0495 1.2345 9.8973
UACC-62 GDSC2; CTRP2 8.7532 16.9283 1.8353 7.625
COLO 792 GDSC2; CTRP2 9.0035 20.3306 0.3956 12.2341
Malme-3M CTRP2 10.2284 31.2918 -4.05 21.9745
EquiPSC Line K2 GDSC2 0.6323 6.6317 -0.8907 33.84
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC2 -1.0391 2.8665 -1.3213 44.4889
KYSE-220 GDSC2 -0.8705 1.716 -0.9355 42.3145
FLO-1 GDSC2 -0.843 3.2471 -1.2031 42.8792
ESO-51 GDSC2 -0.6037 5.0874 -1.547 42.1463
OACM5.1 C GDSC2 -0.063 3.6482 -0.4661 35.7702
TE-12 GDSC2 0.269 5.3944 -0.7386 35.0549
HCE-4 GDSC2 0.6252 4.5658 -0.0346 30.3652
KYSE-50 GDSC2 0.7658 3.924 0.3475 27.8188
ESO-26 GDSC2 0.8921 4.1487 0.406 26.93
KYAE-1 GDSC2 1.8304 6.3854 0.4206 22.8751
SK-GT-4 GDSC2 2.9431 9.9497 -0.3128 22.5931
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 0.5132 4.4568 -0.1139 31.2746
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-DZ GDSC2; CTRP2 -2.6129 0.1571 -2.6187 51.0088
Kelly GDSC2; CTRP2 -2.4018 -0.4101 -2.4023 49.6076
KP-N-YS GDSC2 -1.8856 -0.0317 -1.8892 52.2461
SJNB-6 GDSC2 -1.8431 1.0826 -1.8971 51.7469
CHP-212 GDSC2; CTRP2 -1.7861 0.5004 -1.789 45.5127
GOTO GDSC2 -1.7305 3.3841 -2.209 50.5537
SJNB-14 GDSC2 -1.3891 0.0078 -1.3899 47.2778
SiMa GDSC2 -1.3514 1.3124 -1.4017 46.9984
SK-N-MC-IXC GDSC2 -1.0609 0.2084 -1.0615 43.9847
IMR-32 CTRP2 -1.0104 0.5391 -1.0107 40.3389
SK-N-AS GDSC2; CTRP2 -1.001 2.1948 -1.0459 40.4055
MHH-NB-11 GDSC2; CTRP2 -0.8419 1.3895 -0.8481 39.2352
NB(TU)1 GDSC2 -0.7489 3.8319 -1.2697 42.4241
NB69 GDSC2 -0.6253 1.0669 -0.6344 39.6536
NH-12 GDSC2 -0.5977 1.6268 -0.639 39.517
CHP-134 GDSC2 -0.5492 0.6998 -0.5504 38.8532
SJNB-17 GDSC2 -0.4605 0.8551 -0.4627 37.9677
CHP-126 GDSC2; CTRP2 -0.4426 2.0535 -0.4606 36.6133
SK-N-FI GDSC2; CTRP2 -0.4243 2.0602 -0.4421 36.4912
IMR-5 GDSC2 -0.4176 1.0174 -0.4219 37.5478
NB1 GDSC2; CTRP2 -0.3654 1.9609 -0.3781 36.0825
SJNB-13 GDSC2 -0.3232 2.1237 -0.4045 36.9561
SJNB-5 GDSC2 -0.2405 2.111 -0.3146 36.1004
TGW GDSC2 -0.2281 1.4768 -0.2439 35.7027
SK-N-BE(2)-M17 GDSC2 0.4071 2.1609 0.3667 29.455
SJNB-10 GDSC2 0.4332 2.4169 0.3624 29.347
NH-6 CTRP2 0.5051 3.4254 0.4205 30.5243
SJNB-7 GDSC2 0.5708 3.3294 0.3175 28.9026
KP-N-SI9s CTRP2 0.6706 6.3439 -0.1377 31.7641
SK-N-SH GDSC2; CTRP2 1.0954 4.8904 0.7758 27.4038
KP-N-RT-BM-1 GDSC2 1.1726 4.583 0.5425 24.9478
SJNB-12 GDSC2 1.2269 8.0851 -0.9711 31.5343
SK-N-BE(2) CTRP2 1.4959 7.8637 0.1558 28.2497
LA-N-6 GDSC2 1.5319 7.0934 -0.2049 27.1585
GI-ME-N GDSC2 1.9003 8.9419 -0.7458 28.047
KP-N-YN GDSC2; CTRP2 6.0419 15.6724 0.5371 16.3584
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -2.7714 2.8163 -2.9964 51.8636
HuCC-T1 GDSC2 -1.2531 2.3082 -1.4352 46.2754
SNU-478 CTRP2 -0.0612 3.3491 -0.1728 34.3754
SNU-1196 CTRP2 2.3919 7.8074 1.1106 22.379
SNU-308 CTRP2 3.3907 11.5098 0.3478 22.5292
SNU-869 CTRP2 4.4519 12.2584 0.9325 18.057
HuH-28 CTRP2 4.536 10.725 1.77 14.6686
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 578T GDSC2; CTRP2 -1.716 8.1876 -3.3793 46.6214
CAL-148 GDSC2; CTRP2 -1.3999 0.0981 -1.4 42.9334
HCC1806 GDSC2; CTRP2 -1.1294 1.6756 -1.1495 41.1895
HCC1599 GDSC2 -0.6873 2.166 -0.8007 40.5432
DU4475 GDSC2; CTRP2 -0.4699 1.177 -0.4709 36.7404
CAL-51 GDSC2; CTRP2 -0.238 2.9543 -0.3127 35.4321
HCC1395 GDSC2; CTRP2 -0.0864 4.9021 -0.5168 35.4902
MDA-MB-157 GDSC2; CTRP2 0.0617 6.0345 -0.6927 35.4351
CAL-85-1 GDSC2; CTRP2 0.1488 4.5245 -0.1659 33.6226
BT-549 GDSC2; CTRP2 0.4277 3.6195 0.3114 31.1446
MDA-MB-468 GDSC2; CTRP2 0.5615 3.4394 0.4787 30.1428
HCC1143 GDSC2; CTRP2 0.7153 4.2466 0.5114 29.5279
HCC1569 GDSC2; CTRP2 0.7659 5.8318 0.1386 30.5895
SK-BR-3 CTRP2 0.8114 5.029 0.429 29.4913
HDQ-P1 GDSC2; CTRP2 0.8924 6.8257 -0.0731 30.8437
MFM-223 GDSC2 1.0068 4.2076 0.5082 25.7819
HCC1954 GDSC2; CTRP2 1.2095 5.6087 0.6926 27.3312
HCC38 GDSC2; CTRP2 1.2225 6.0903 0.5473 27.7876
AU565 GDSC2; CTRP2 1.3528 6.1365 0.6722 26.9577
Evsa-T GDSC2 1.4022 3.7419 1.0988 20.8167
MDA-MB-453 GDSC2; CTRP2 1.5059 4.1445 1.386 23.9829
COLO 824 GDSC2 1.6609 5.0745 0.8488 21.1232
JIMT-1 GDSC2; CTRP2 1.7575 5.8159 1.2205 23.7946
BT-20 GDSC2; CTRP2 1.7947 6.2383 1.1127 24.072
OCUB-M GDSC2 1.9106 4.1452 1.4987 16.3779
CAL-120 GDSC2; CTRP2 2.1071 6.0867 1.5041 21.7283
MRK-nu-1 GDSC2 2.1713 3.8763 1.8808 13.0939
HCC2157 GDSC2 2.2816 6.2311 0.9299 18.2808
MDA-MB-231 GDSC2; CTRP2 2.3133 8.0089 0.9418 23.2103
BT-474 GDSC2; CTRP2 2.5177 6.7144 1.702 19.8196
MDA-MB-175-VII GDSC2 2.6116 7.2626 0.7323 18.259
HCC70 GDSC2 2.7082 7.0736 0.9129 16.9004
HCC1937 GDSC2; CTRP2 2.7965 9.2306 0.8739 22.1649
HCC1187 GDSC2 2.8698 4.1389 2.4947 6.6959
EFM-19 GDSC2 2.9226 6.8382 1.2209 14.3789
MDA-MB-436 GDSC2 3.0216 7.6939 0.8809 16.0729
MDA-MB-330 GDSC2 3.0346 8.1666 0.6562 17.3078
HCC202 CTRP2 3.1013 9.5352 1.028 20.8256
UACC-812 GDSC2 3.2724 6.1908 1.846 9.4493
MCF-7 GDSC2; CTRP2; CTRP1 3.4637 9.9331 1.1916 19.3984
EFM-192A GDSC2; CTRP2 3.594 7.6814 2.3833 14.3322
UACC-893 GDSC2 3.9478 8.9035 1.034 12.5186
HCC2218 GDSC2 4.1572 7.9703 1.6518 8.3163
HCC1428 GDSC2; CTRP2 4.8382 11.2916 1.7474 14.1353
YMB-1-E GDSC2 4.9647 8.6521 1.8698 5.3553
CAMA-1 GDSC2; CTRP2 4.965 9.4612 2.7694 9.7076
KPL-1 CTRP2 5.1864 9.557 2.9054 8.7142
MDA-MB-415 GDSC2; CTRP2 5.395 11.5886 2.0597 11.8045
ZR-75-1 CTRP2 5.4244 10.7061 2.5236 9.8581
HCC1500 GDSC2; CTRP2 5.5907 12.4686 1.7772 12.5702
HCC1419 GDSC2; CTRP2 5.6027 13.3587 1.3429 14.23
MDA-MB-361 GDSC2; CTRP2 5.7361 11.8529 2.198 10.6287
T-47D GDSC2; CTRP2 5.909 14.4124 1.06 14.729
BT-483 GDSC2 6.115 14.6869 -0.2351 14.0816
Hs 578Bst CTRP2 7.145 18.2659 0.0921 15.968
ZR-75-30 GDSC2; CTRP2 7.7529 14.1903 2.4834 6.4759
BT 231 CTRP2 0.6514 2.8173 0.6288 29.3425
BT 271 CTRP2 1.1741 8.463 -0.4319 31.0195
BT 145 CTRP2 1.2525 3.86 1.1591 25.5788
BT 416 CTRP2 1.3031 3.2455 1.2777 25.0102
BT 179 CTRP2 1.7206 4.2738 1.5946 22.5742
BT164 CTRP2 1.9017 5.0238 1.6203 21.9183
BT 428 CTRP2 1.9059 9.7737 -0.2629 28.36
BT 112 CTRP2 2.185 5.4295 1.8108 20.3721
BT 172 CTRP2 2.348 8.4277 0.792 23.6521
BT 131 CTRP2 2.3862 6.6805 1.5766 20.6601
BT 245 CTRP2 2.3976 6.7659 1.5544 20.7113
BT 159 CTRP2 2.4462 7.9215 1.1165 22.2092
BT 187 CTRP2 2.9517 8.1282 1.5373 19.2849
BT 286 CTRP2 3.1357 8.5187 1.5406 18.8021
BT 216 CTRP2 3.3824 8.6749 1.709 17.5331
BT 504 CTRP2 3.7139 9.7146 1.5251 17.4572
BT 239 CTRP2 3.7831 10.3669 1.2707 18.2751
BT147 CTRP2 3.8605 14.1471 -0.5277 24.2254
BT 228 CTRP2 3.9763 8.5168 2.3537 13.5394
BT 440 CTRP2 4.7809 11.3309 1.679 14.5222
BT 359 CTRP2 4.8347 11.6784 1.5511 14.9149
BT 224 CTRP2 5.2227 9.1513 3.1376 7.6751
BT 482 CTRP2 5.4646 13.5715 1.1258 15.3058
BT 248 CTRP2 5.5286 10.0674 2.9241 8.0131
BT 139 CTRP2 5.9314 10.7842 2.876 7.5281
BT 340 CTRP2 6.3241 18.1316 -0.4657 19.1189
BT 498 CTRP2 6.561 7.6726 4.6812 0.1641
BT 320 CTRP2 6.8175 7.942 4.6817 0.105
BT 444 CTRP2 6.8491 8.2704 4.5764 0.257
BT 328 CTRP2 7.2202 16.7474 0.8922 13.1317
BT 330 CTRP2 7.482 19.6325 -0.3313 16.7661
BT 232 CTRP2 8.2059 16.1948 1.8324 8.3163
BT 422 CTRP2 8.3976 19.989 0.1484 13.8718
BT 333 CTRP2 8.7432 19.5399 0.5991 11.9169
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 0.582 4.64 0.2786 30.7405
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AM-38 GDSC2; CTRP2 -10.2282 4.4658 -11.4687 74.3069
SF539 GDSC2; CTRP2 -1.9317 -0.0294 -1.9322 46.4769
H4 GDSC2 -1.3004 2.256 -1.4766 46.7055
Daoy GDSC2 -0.9586 1.2133 -0.9843 43.0535
KNS-60 CTRP2 -0.8238 1.3795 -0.8296 39.1134
GI-1 GDSC2 -0.7295 1.5887 -0.7739 40.8425
MOG-G-UVW GDSC2 -0.6842 1.3908 -0.711 40.3201
LNZTA3WT4 GDSC2 -0.387 2.3238 -0.5034 37.7397
PFSK-1 GDSC2 -0.3314 3.1125 -0.6099 37.8432
D283 Med GDSC2; CTRP2 -0.1526 1.0333 -0.1527 34.6233
D-336MG GDSC2 -0.0391 3.5542 -0.412 35.4188
D-423MG GDSC2 0.0013 3.9697 -0.4975 35.5459
TM-31 CTRP2 0.0256 3.4812 -0.0987 33.8398
Hs 683 GDSC2; CTRP2 0.0687 3.7464 -0.0944 33.6774
SK-MG-1 GDSC2 0.5456 4.6519 -0.1523 31.291
KALS-1 GDSC2; CTRP2 0.5598 4.5144 0.2841 30.7961
D-566MG GDSC2 0.5634 3.2621 0.3276 28.8874
SNU-738 CTRP2 0.8284 3.9047 0.697 28.5314
M059J GDSC2 0.9916 4.6615 0.3193 26.9231
GaMG GDSC2; CTRP2; CTRP1 1.1186 4.7951 0.8278 27.2204
LN-18 GDSC2; CTRP2 1.1554 4.1821 1.0007 26.436
MOG-G-CCM GDSC2 1.2591 4.7391 0.5714 24.415
8-MG-BA GDSC2; CTRP2 1.3297 4.4311 1.14 25.3978
T98G GDSC2; CTRP2 1.3382 6.6922 0.4547 27.7434
D-263MG GDSC2 1.6844 5.1991 0.8182 21.2724
M059K CTRP2 1.7598 4.6961 1.5486 22.6124
SF126 GDSC2; CTRP2 1.8477 3.9605 1.7809 21.523
A-172 GDSC2; CTRP2 2.1751 8.0823 0.7678 24.2153
Becker GDSC2; CTRP2 2.1989 7.1935 1.1706 22.6948
KNS-42 GDSC2; CTRP2 2.2093 6.3689 1.5093 21.4136
D-502MG GDSC2 2.2801 8.2187 -0.041 23.5475
SF268 GDSC2; CTRP2 2.303 7.5843 1.115 22.6082
SNU-626 CTRP2 2.3099 8.0752 0.9093 23.3367
LN-229 GDSC2; CTRP2; CTRP1 2.3695 10.5508 -0.1576 26.8236
SW1088 GDSC2; CTRP2 2.4482 9.5422 0.3845 24.7957
YH-13 GDSC2; CTRP2 2.5552 6.547 1.8087 19.3113
D-542MG GDSC2 2.6891 5.6763 1.5832 12.9837
KS-1 [Human Krukenberg tumour] GDSC2 2.8171 7.8676 0.6158 18.287
YKG-1 GDSC2; CTRP2 2.8235 6.4959 2.1132 17.4062
ONS-76 GDSC2; CTRP2 3.0156 8.0757 1.6254 18.7809
Onda 10 GDSC2 3.0641 6.1888 1.6684 11.2284
D-247MG GDSC2 3.2005 9.6706 0.0458 20.072
D-245MG GDSC2 3.4029 8.6512 0.7244 15.8575
DK-MG GDSC2; CTRP2 3.4523 10.824 0.7401 21.0136
SNB-75 GDSC2; CTRP2 3.5666 8.5611 1.9416 16.1666
SF295 GDSC2; CTRP2; CTRP1 3.8166 11.8173 0.5957 20.7398
KINGS-1 GDSC2 3.8318 8.9916 0.9 13.6438
Onda 11 GDSC2 3.9261 7.6902 1.6186 9.1148
LN-405 GDSC2 4.0073 10.3481 0.3624 16.1243
GMS-10 CTRP2 4.0807 8.4586 2.48 12.7839
CAS-1 GDSC2; CTRP2 4.0899 11.1719 1.1529 18.0257
KG-1-C CTRP2 4.121 16.6692 -1.5543 26.4728
GB-1 GDSC2; CTRP2 4.3402 12.256 0.8362 18.6479
NMC-G1 GDSC2 4.344 8.8777 1.3429 9.7522
CCF-STTG1 CTRP2 4.6105 11.3119 1.5421 15.4107
SNU-1105 CTRP2 4.762 11.8969 1.3801 15.7256
KNS-81-FD GDSC2 5.033 8.4387 2.0098 4.4456
42-MG-BA GDSC2; CTRP2 5.0521 15.3647 -0.1093 20.3984
U-251MG GDSC2; CTRP2 5.1051 11.6475 1.7932 13.4238
SNU-489 CTRP2 5.5259 22.1008 -3.0859 27.1914
SW1783 GDSC2; CTRP2 5.6052 13.4762 1.2863 14.4401
GOS-3 CTRP2 5.7444 13.6565 1.3068 14.1065
DBTRG-05MG GDSC2; CTRP2 5.7639 14.6715 0.8165 15.8784
KNS-81 CTRP2 5.785 10.3229 2.9941 7.2835
D-392MG GDSC2 6.0567 13.6993 0.1972 12.2083
U-118MG GDSC2; CTRP2 6.3498 14.7828 1.2157 13.3811
U-87MG ATCC GDSC2; CTRP2 7.3188 14.8244 1.8955 9.2926
SNU-466 CTRP2 8.0624 18.4602 0.6547 12.6852
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 0.6209 4.8939 -0.166 30.9897
ETK-1 GDSC2 0.8209 5.1691 -0.0657 29.5888
TGBC1TKB GDSC2 3.9012 9.9494 0.4777 15.8005
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-1 CTRP2 -3.5939 2.8519 -3.8875 56.4429
JHUEM-7 CTRP2 -2.5344 -0.4961 -2.5349 50.4907
HEC-6 CTRP1 -2.0188 0.6717 -2.0263 88.4726
JHUEM-3 CTRP2 -1.4716 4.4077 -1.9035 44.1769
HEC-265 CTRP1 -0.406 4.3249 -0.7219 68.1368
ESS-1 GDSC2; CTRP2 -0.3434 2.1142 -0.3614 35.953
JHUEM-2 CTRP2; CTRP1 -0.2444 2.1422 -0.2608 35.3511
RL95-2 GDSC2; CTRP2 -0.2211 2.2196 -0.2404 35.1429
HEC-50B CTRP2 0.171 6.3799 -0.6906 35.0415
HEC-151 CTRP2; CTRP1 0.2313 3.0361 0.1744 32.3197
EN GDSC2; CTRP2 0.3009 4.3903 0.0305 32.4857
HEC-251 CTRP1 0.3012 3.166 0.2351 65.3731
MFE-319 GDSC2; CTRP2; CTRP1 0.4543 3.9964 0.2789 31.2298
AN3-CA GDSC2; CTRP2 0.4854 2.9375 0.4485 30.4962
HEC-108 CTRP1 0.6149 4.5093 0.3473 60.0928
KLE GDSC2; CTRP2; CTRP1 0.8262 6.5879 -0.0526 31.0575
HEC-59 CTRP1 0.9754 3.6023 0.8993 57.4561
MFE-296 GDSC2; CTRP2 1.1255 4.6458 0.8694 26.9848
HEC-1-B CTRP2 1.757 10.4293 -0.7127 30.0788
HEC-1-A CTRP2 2.1547 7.6873 0.917 23.7403
MFE-280 GDSC2 2.3972 7.1119 0.6102 19.7454
EFE-184 CTRP2 4.1277 9.7858 1.8723 15.1432
Ishikawa (Heraklio) 02 ER- CTRP1 -1.8816 0.3192 -1.8835 89.6613
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMRC-3 CTRP2 -1.3953 4.643 -1.8781 43.7888
LB996-RCC GDSC2 -1.1352 3.6385 -1.6322 45.7012
LB2241-RCC GDSC2 -1.1308 1.4135 -1.1793 44.8301
KTCTL-140 GDSC2 -1.0784 1.6138 -1.1442 44.3619
BFTC-909 GDSC2 -0.9247 2.4107 -1.0994 43.169
CAL-54 GDSC2; CTRP2 -0.5526 6.227 -1.4233 39.442
KTCTL-13 GDSC2 -0.5404 2.9889 -0.8071 39.7956
769-P GDSC2; CTRP2 -0.5248 3.0824 -0.6316 37.4296
ACHN GDSC2; CTRP2 -0.2774 3.9334 -0.5022 36.1444
NCC010 GDSC2 -0.1761 1.8177 -0.2138 35.2867
UO-31 GDSC2; CTRP2 0.3134 4.848 -0.0664 32.748
KTCTL-26A GDSC2 0.6618 5.3046 -0.2885 31.3364
BB65-RCC GDSC2 0.7604 5.9802 -0.4726 31.6516
RXF 393L GDSC2 1.087 6.6303 -0.4302 30.0127
A-498 GDSC2 1.0888 8.5644 -1.3327 33.3284
LB1047-RCC GDSC2 1.1045 6.774 -0.4785 30.1392
TUHR4TKB CTRP2 1.5152 13.2092 -2.2544 34.3669
SW13 GDSC2 1.5416 4.8121 0.8376 21.7509
VMRC-RCW GDSC2; CTRP2; CTRP1 1.7913 6.1472 1.146 24.0346
KMRC-20 GDSC2; CTRP2 1.7928 7.5928 0.5794 25.9617
TK-10 GDSC2 1.8636 8.2537 -0.4443 26.9286
SW156 GDSC2 1.9224 6.7722 0.3263 23.0179
A-704 GDSC2 2.0826 9.3544 -0.7806 27.521
786-O GDSC2; CTRP2 2.1304 7.6544 0.9058 23.8486
SNU-1272 CTRP2 2.138 6.289 1.463 21.7903
Caki-1 GDSC2; CTRP2 2.2122 8.4253 0.6548 24.5096
KTCTL-21 GDSC2 2.2478 6.8655 0.591 20.3849
HA7-RCC GDSC2 2.4021 7.4831 0.4326 20.6966
SN12C GDSC2 2.9576 9.3623 -0.007 21.0948
NCC021 GDSC2 3.1383 8.6155 0.5206 17.7881
KMRC-2 CTRP2 3.2457 10.1402 0.877 21.0205
KMRC-1 GDSC2; CTRP2 3.3565 8.739 1.6535 17.8138
KTCTL-1M GDSC2 3.5653 6.5047 1.9285 8.1336
KTCTL-195 GDSC2 3.5661 8.5303 0.9183 14.2772
VMRC-RCZ GDSC2; CTRP2 4.1006 9.977 1.7533 15.6775
TUHR10TKB CTRP2 4.5825 14.4017 -0.0245 21.0884
RCC10RGB GDSC2; CTRP2; CTRP1 5.1383 13.7648 0.7719 17.298
OS-RC-2 GDSC2; CTRP2 5.7416 12.6854 1.7882 12.2536
Caki-2 CTRP2 5.7932 15.9746 0.1901 17.9917
TUHR14TKB CTRP2 6.4272 10.285 3.4676 4.3849
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320HSR GDSC2 -1.7331 1.0499 -1.7791 50.5297
SNU-283 GDSC2 -1.6241 1.3135 -1.6886 49.6509
CL-34 CTRP1 -1.2325 2.3076 -1.2962 78.8917
LoVo GDSC2; CTRP2; CTRP1 -1.1961 2.5663 -1.2826 41.8551
SNU-175 GDSC2; CTRP1 -0.9486 2.5401 -1.0192 51.1271
KM12 GDSC2; CTRP2; CTRP1 -0.8313 2.0166 -0.8586 39.2873
CL-40 CTRP1 -0.7348 12.3367 -4.0818 59.2649
SNU-C5 GDSC2; CTRP2; CTRP1 -0.7073 4.4049 -1.0681 39.3383
SW948 GDSC2; CTRP2; CTRP1 -0.6971 1.8888 -0.7147 38.366
SNU-C4 CTRP2; CTRP1 -0.6891 2.5668 -0.7492 38.4401
CCK-81 GDSC2; CTRP2 -0.5607 2.4776 -0.6079 37.4905
T84 GDSC2; CTRP2 -0.4531 2.2207 -0.4794 36.7101
GP5d GDSC2 -0.3973 1.2529 -0.4078 37.2431
GP2d CTRP2 -0.3712 2.7163 -0.4295 36.2655
HCC2998 GDSC2 -0.2111 2.258 -0.304 35.769
HCT 15 GDSC2; CTRP2 -0.1492 3.0639 -0.2308 34.8642
LS513 GDSC2; CTRP2 -0.1405 2.6767 -0.1847 34.6872
SNU-61 GDSC2; CTRP2; CTRP1 0.0181 5.0474 -0.4392 34.9547
SNU-503 CTRP2 0.1126 5.5924 -0.4969 34.7211
RKO GDSC2; CTRP2; CTRP1 0.1637 3.267 0.0781 32.863
SW48 GDSC2; CTRP2 0.1827 2.7607 0.1461 32.5108
CL-11 GDSC2; CTRP2 0.2462 5.1849 -0.2311 33.4819
NCI-H747 GDSC2; CTRP2 0.2729 4.495 -0.0238 32.753
DiFi GDSC2 0.2737 4.8636 -0.5237 34.1115
SNU-C2B GDSC2 0.2838 5.5099 -0.7701 34.9891
SK-CO-1 GDSC2; CTRP2 0.3657 4.5902 0.0549 32.1879
HT115 GDSC2; CTRP2; CTRP1 0.4453 3.4607 0.3533 31.0135
SW837 GDSC2 0.4528 3.722 0.073 30.5885
LS180 GDSC2; CTRP1 0.5454 3.4797 0.4574 38.7855
CW-2 GDSC2; CTRP2; CTRP1 0.5829 6.661 -0.3411 32.7193
SNU-C2A CTRP2; CTRP1 0.6304 5.1557 0.1991 30.9054
SNU-81 GDSC2; CTRP2; CTRP1 0.7012 5.3197 0.2295 30.5739
COLO 320 CTRP2; CTRP1 0.7125 7.8625 -0.6628 33.1862
SW1463 GDSC2 0.7301 5.0269 -0.1034 30.0888
SNU-407 GDSC2; CTRP2 0.7691 4.5734 0.4983 29.3965
LS123 GDSC2; CTRP2; CTRP1 0.8177 5.5206 0.2965 29.9756
HT-55 GDSC2; CTRP2; CTRP1 0.8571 3.9735 0.7176 28.4369
HCT 116 GDSC2; CTRP2; CTRP1 0.9079 4.2317 0.7249 28.2475
LS1034 GDSC2; CTRP2 1.0751 3.6054 1.004 26.6841
SNU-1040 GDSC2; CTRP1 1.1146 5.3815 0.6622 35.3484
COLO205 GDSC2; CTRP2 1.1397 3.8865 1.0343 26.371
SNU-C1 GDSC2; CTRP2 1.1793 3.8224 1.0862 26.0652
NCI-H508 GDSC2; CTRP2; CTRP1 1.2109 5.8858 0.6077 27.6864
NCI-H716 GDSC2; CTRP2 1.2818 4.5634 1.0588 25.8324
SW620 GDSC2; CTRP2; CTRP1 1.3575 5.8537 0.7775 26.6479
SW1417 GDSC2; CTRP2 1.3967 7.7616 0.0942 28.7456
RCM-1 [Human ESC] GDSC2; CTRP2; CTRP1 1.4232 7.2434 0.337 27.9431
LS411N GDSC2; CTRP2 1.6559 6.2563 0.9567 25.0433
SNU-1033 CTRP2 1.7488 5.5627 1.294 23.5561
CaR-1 GDSC2 1.8933 5.7211 0.7928 20.5172
C2BBe1 GDSC2; CTRP2 1.9834 8.4363 0.4159 25.9713
SW626 GDSC2 2.2084 7.363 0.3121 22.0269
HCT 8 CTRP2; CTRP1 2.272 5.2089 1.9752 19.5899
OUMS-23 CTRP2 2.3265 5.6913 1.8794 19.7012
SW1116 GDSC2; CTRP2 2.918 8.7375 1.2235 20.5631
HCC-56 CTRP2 3.2195 10.0578 0.8917 21.0317
SW403 CTRP1 3.2504 13.5086 -0.7538 41.4243
HT-29 GDSC2; CTRP2; CTRP1 3.3346 9.1319 1.453 18.7182
MDST8 GDSC2; CTRP2; CTRP1 5.0558 12.2591 1.4562 14.9124
COLO201 CTRP2 5.105 14.5261 0.354 18.7613
DLD-1 CTRP2 5.2027 8.679 3.3572 6.7914
COLO 678 GDSC2; CTRP2; CTRP1 6.0425 16.4001 0.1857 17.6101
SW480 CTRP1 7.3792 22.4826 -1.8028 30.3675
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 3.0426 6.8223 1.3338 13.3621
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Li-7 CTRP2 -6.6745 12.1679 -10.2084 61.3663
SNU-182 CTRP2 -2.2339 4.3131 -2.7115 48.7146
HuH-6 CTRP2 -1.8016 4.2135 -2.2175 46.1453
SNU-398 GDSC2; CTRP2; CTRP1 -0.9624 4.3101 -1.3241 40.9544
HLF CTRP2 0.2767 4.6055 -0.0458 32.8088
JHH-1 GDSC2; CTRP2 0.6514 3.9087 0.5056 29.7568
HLE GDSC2 0.734 3.6319 0.4073 27.6615
Hep 3B2.1-7 GDSC2; CTRP2 0.8501 2.2768 0.848 27.95
PLC/PRF/5 CTRP2 1.0778 7.245 -0.0353 30.137
JHH-5 CTRP2 1.3958 7.5483 0.1806 28.4714
SNU-423 GDSC2; CTRP2 1.4244 5.5594 0.942 25.7971
HuH-1 GDSC2; CTRP2 1.5078 6.3853 0.7505 26.2141
JHH-7 GDSC2 1.5633 4.73 0.8947 21.3398
JHH-2 GDSC2; CTRP2 1.6465 7.4353 0.4907 26.6935
Hep-G2/C3A GDSC2 2.0538 8.7622 -0.5159 26.5303
JHH-4 GDSC2; CTRP2 3.2596 9.6193 1.1405 20.0149
SNU-761 CTRP2 3.3128 8.3925 1.774 17.4503
SNU-449 GDSC2; CTRP2; CTRP1 4.6078 10.1138 2.1464 13.0795
Huh-7 GDSC2 4.6347 9.5845 1.2058 9.878
Hep-G2 CTRP2; CTRP1 4.8354 12.5705 1.1153 16.6492
SNU-475 CTRP2 5.4982 15.1745 0.3524 18.0007
JHH-6 GDSC2; CTRP2; CTRP1 5.8822 13.9351 1.2868 14.0011
SNU-387 GDSC2; CTRP2 6.01 14.9639 0.8646 15.2587
SK-HEP-1 GDSC2; CTRP2 7.2294 13.8801 2.2881 7.9163
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 221 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCLC-21H CTRP1 -3.0473 -1.1518 -3.0474 96.9837
COR-L51 CTRP2; CTRP1 -2.3234 0.3615 -2.3292 49.1378
NCI-H322M GDSC2 -2.2426 0.3112 -2.2618 55.6753
NCI-H847 GDSC2 -2.2086 -0.8149 -2.2088 55.4943
NCI-H64 GDSC2 -2.1203 0.7893 -2.163 54.3996
A-427 GDSC2 -1.899 -0.1278 -1.9015 52.3827
NCI-H1703 GDSC2; CTRP2 -1.8055 0.2828 -1.8069 45.6385
NCI-H209 GDSC2 -1.73 1.776 -1.8592 50.6379
IST-SL1 GDSC2 -1.7168 0.5255 -1.7314 50.5558
NCI-H1876 GDSC2; CTRP1 -1.647 0.0252 -1.6472 57.2974
LC-1/sq GDSC2 -1.6184 3.1294 -2.0183 49.6534
LB647-SCLC GDSC2 -1.537 1.6013 -1.6291 48.8334
EPLC-272H GDSC2; CTRP2; CTRP1 -1.4778 8.1903 -3.1211 45.5096
NCI-H2009 GDSC2; CTRP2; CTRP1 -1.4671 2.2087 -1.5334 43.5891
NCI-H1734 GDSC2; CTRP2 -1.4218 1.0242 -1.4284 43.0974
NCI-H23 GDSC2; CTRP1 -1.3209 1.0398 -1.3266 54.4785
COR-L23 GDSC2; CTRP1 -1.2808 4.2852 -1.665 53.4185
LUDLU-1 CTRP2 -1.2573 3.0825 -1.4136 42.3546
LCLC-97TM1 GDSC2; CTRP2; CTRP1 -1.2165 1.809 -1.2451 41.8471
HARA [Human squamous cell lung carcinoma] GDSC2; CTRP2 -1.1809 2.6979 -1.2818 41.7336
DV-90 CTRP2 -1.0045 2.9811 -1.1293 40.6355
NCI-H1568 GDSC2; CTRP2; CTRP1 -1.0021 2.8809 -1.1131 40.6417
IST-SL2 GDSC2 -0.9214 3.9809 -1.5044 44.0379
NCI-H1963 GDSC2; CTRP1 -0.8743 1.0138 -0.876 50.7004
CPC-N GDSC2 -0.8265 1.1441 -0.8439 41.7043
PC-14 GDSC2; CTRP2 -0.7944 1.8358 -0.8124 38.9553
NCI-H2122 GDSC2; CTRP2; CTRP1 -0.775 1.4338 -0.781 38.8479
NCI-H2286 CTRP2; CTRP1 -0.7415 3.9034 -0.9973 39.3049
NCI-H810 GDSC2; CTRP2; CTRP1 -0.6974 1.9266 -0.7165 38.3723
Lu-134-A GDSC2 -0.5885 3.0433 -0.8729 40.3094
NCI-H446 GDSC2; CTRP2 -0.5768 2.9254 -0.6679 37.7276
Lu-65 GDSC2; CTRP2 -0.5451 3.1579 -0.6631 37.596
SBC-1 GDSC2 -0.5092 0.8816 -0.5122 38.4604
NCI-H1792 GDSC2; CTRP2; CTRP1 -0.4402 2.4925 -0.4829 36.7366
COR-L303 GDSC2 -0.4397 1.1108 -0.4465 37.7812
NCI-H1048 GDSC2; CTRP1 -0.4373 1.1086 -0.4379 46.9696
HCC33 GDSC2 -0.4261 0.4229 -0.4262 37.6125
NCI-H510A GDSC2 -0.4075 0.528 -0.4076 37.4256
NCI-H2073 CTRP1 -0.3629 8.6806 -2.1286 60.8519
NCI-H2171 GDSC2; CTRP2 -0.3353 1.4097 -0.3371 35.8463
LK-2 GDSC2 -0.2898 1.9324 -0.3452 36.507
NCI-H524 GDSC2; CTRP2 -0.2894 3.1733 -0.3928 35.8619
Calu-6 GDSC2; CTRP2; CTRP1 -0.279 2.9871 -0.3588 35.7819
NCI-H1648 GDSC2 -0.219 3.4628 -0.5818 37.0924
RERF-LC-Sq1 GDSC2 -0.2058 4.3013 -0.8338 37.9185
COLO 699 CTRP2; CTRP1 -0.1526 2.7918 -0.2063 34.8608
NCI-H2110 GDSC2; CTRP2; CTRP1 -0.1407 3.0529 -0.2198 34.8627
NCI-H1341 GDSC2; CTRP2 -0.1329 2.4071 -0.1588 34.5771
NCI-H838 GDSC2; CTRP2 -0.1234 2.1432 -0.1371 34.4737
HCC44 GDSC2; CTRP2 -0.1166 4.0532 -0.3516 35.1198
NCI-H211 GDSC2; CTRP2 -0.0828 2.8469 -0.1386 34.3405
NCI-H1437 GDSC2; CTRP1 -0.069 3.0827 -0.1473 44.035
NCI-H1694 GDSC2; CTRP2; CTRP1 -0.0606 2.2057 -0.0749 34.1212
HCC4006 CTRP2; CTRP1 -0.0223 3.1057 -0.1004 34.0735
NCI-H1436 GDSC2 0.0385 2.1539 -0.0231 33.2543
NCI-H526 GDSC2; CTRP2 0.0567 1.5475 0.0558 33.2319
EMC-BAC-1 GDSC2 0.0689 3.3978 -0.2493 34.1446
NCI-H1105 GDSC2; CTRP2; CTRP1 0.0756 1.9894 0.0699 33.1862
NCI-H2081 GDSC2; CTRP2; CTRP1 0.0858 4.6899 -0.2723 34.2272
NCI-H1975 GDSC2; CTRP1 0.0953 5.5742 -0.5071 43.7627
Ms-1 GDSC2 0.0971 2.1206 0.0432 32.6301
NCI-H520 GDSC2; CTRP2 0.1077 3.6433 -0.0354 33.3558
COR-L321 GDSC2 0.1233 2.3602 0.039 32.5172
COR-L88 GDSC2; CTRP1 0.131 3.9552 -0.0629 42.663
ChaGo-K-1 GDSC2; CTRP2; CTRP1 0.1605 2.5779 0.1351 32.6866
NCI-H1836 GDSC2; CTRP1 0.183 3.7488 0.0296 42.133
SBC-5 GDSC2; CTRP2 0.2184 1.9478 0.2149 32.1631
NCI-H1299 GDSC2; CTRP2; CTRP1 0.23 4.4999 -0.0696 33.1073
NCI-H3255 GDSC2; CTRP1 0.2326 4.915 -0.1696 42.3339
NCI-H841 GDSC2; CTRP2; CTRP1 0.2481 3.1356 0.1822 32.2379
NCI-H3122 GDSC2 0.2962 3.8502 -0.1381 32.4675
NCI-H1944 GDSC2; CTRP2; CTRP1 0.3257 5.4364 -0.2144 33.22
DMS 273 GDSC2; CTRP2; CTRP1 0.3318 2.5727 0.3122 31.5271
COR-L311 GDSC2 0.3357 2.9155 0.1643 30.8277
NCI-H661 GDSC2; CTRP2 0.3504 5.1864 -0.1178 32.7798
SK-MES-1 GDSC2; CTRP2 0.3573 6.9729 -0.702 34.423
UMC-11 GDSC2 0.3618 3.54 0.0294 31.3549
HCC1438 CTRP2 0.3778 1.2821 0.3778 31.0897
NCI-H82 GDSC2; CTRP1 0.3931 2.476 0.3794 39.9253
VMRC-LCD GDSC2; CTRP2; CTRP1 0.4 3.824 0.2506 31.5041
HCC827 GDSC2; CTRP2; CTRP1 0.4288 4.3504 0.1803 31.6371
SHP-77 GDSC2; CTRP2 0.4385 2.2004 0.4334 30.7019
NCI-H146 GDSC2 0.4652 3.9918 -0.0014 30.9872
LXF 289 GDSC2; CTRP2; CTRP1 0.5343 3.698 0.415 30.5131
RERF-LC-MS GDSC2; CTRP2 0.5373 3.8 0.401 30.483
HCC1588 CTRP2 0.5581 3.0793 0.513 30.0395
NCI-H835 GDSC2 0.5593 5.7166 -0.5678 32.9806
NCI-H2461 GDSC2 0.566 9.502 -2.2847 38.0124
Lu-135 GDSC2 0.5979 4.5756 -0.0674 30.6492
NCI-H647 GDSC2; CTRP2 0.6042 5.62 0.0301 31.4657
NCI-H889 CTRP2 0.6275 3.1189 0.5823 29.5773
NCI-H522 GDSC2; CTRP2 0.6347 4.5643 0.354 30.3181
LK2 CTRP2 0.6436 1.0849 0.6436 29.3188
NCI-H1184 CTRP2 0.6461 5.1713 0.2092 30.7552
NCI-H1993 GDSC2 0.6475 4.0186 0.1871 29.1883
NCI-H720 GDSC2 0.6735 5.0501 -0.1725 30.7682
NCI-H358 GDSC2; CTRP2 0.6999 5.8068 0.0749 31.0086
NCI-H69 GDSC2 0.7646 2.4552 0.7111 25.9354
NCI-H290 GDSC2 0.7857 4.3142 0.2314 28.3147
NCI-H1155 GDSC2; CTRP2 0.8215 2.2946 0.819 28.142
NCI-H1651 GDSC2; CTRP2 0.8402 4.6725 0.5522 28.9844
HCC95 CTRP2 0.8433 4.9969 0.4725 29.2428
NCI-H2810 GDSC2 0.8461 5.1718 -0.0403 29.3535
Lu-99 CTRP2 0.8759 4.9714 0.5149 28.9949
HCC15 GDSC2; CTRP2; CTRP1 0.8778 4.208 0.697 28.4398
NCI-H1915 GDSC2; CTRP2; CTRP1 0.9188 7.6555 -0.3615 31.6796
NCI-H2141 GDSC2; CTRP2; CTRP1 0.9202 9.0225 -0.9287 33.2128
NCI-H1339 CTRP2 0.9563 3.7818 0.8534 27.5834
HCC1833 CTRP2; CTRP1 0.9606 10.412 -1.4988 34.4428
LC-2/ad GDSC2 0.9696 4.9124 0.1958 27.6466
NCI-H1930 CTRP1 0.9924 4.4553 0.77 56.4806
COLO 668 GDSC2; CTRP2; CTRP1 1.0139 4.7079 0.7352 27.8719
NCI-H748 GDSC2 1.1014 4.5577 0.4768 25.612
NCI-H2228 GDSC2; CTRP2 1.1026 7.5306 -0.122 30.3257
COR-L279 GDSC2; CTRP1 1.1037 3.852 1.002 34.2209
NCI-H196 GDSC2; CTRP2 1.1109 6.2064 0.3863 28.6775
Sq-1 CTRP2; CTRP1 1.1132 5.2456 0.7004 27.6758
DMS 454 CTRP2 1.1241 7.5173 -0.094 30.1727
NCI-H250 GDSC2 1.1241 5.8029 -0.0214 28.0175
SBC-3 GDSC2 1.1482 2.8671 1.0566 22.2863
NCI-H1666 GDSC2; CTRP2; CTRP1 1.1487 8.5692 -0.4979 31.3447
NCI-H596 GDSC2; CTRP1 1.2221 4.9375 0.9041 34.0726
NCI-H1688 GDSC2 1.2389 5.2789 0.3246 25.8038
NCI-H1581 GDSC2; CTRP2 1.311 5.1239 0.948 26.1274
NCI-H1355 GDSC2; CTRP2; CTRP1 1.3196 8.3277 -0.2176 30.0056
NCI-H2029 GDSC2; CTRP2; CTRP1 1.3262 4.5166 1.1196 25.5516
NCI-H2731 GDSC2 1.3449 6.4064 -0.0695 27.2995
NCI-H1755 GDSC2; CTRP2; CTRP1 1.3469 8.7584 -0.3736 30.3827
NCI-H2804 GDSC2 1.3609 7.1643 -0.4055 28.7473
LC-1/sq-SF CTRP2 1.3707 6.4599 0.5758 27.2336
LCLC-103H GDSC2; CTRP2 1.3909 4.7193 1.1411 25.2011
COR-L32 GDSC2 1.3961 6.565 -0.0915 27.1892
PaCa-3 GDSC2 1.3984 6.4724 -0.0465 26.9667
RERF-LC-KJ GDSC2; CTRP1 1.4002 5.2145 1.0225 32.8237
NCI-H292 GDSC2; CTRP2 1.4027 7.4999 0.2075 28.3633
NCI-H2172 GDSC2; CTRP2; CTRP1 1.4151 4.618 1.1934 25.0137
A-549 GDSC2; CTRP2; CTRP1 1.4216 4.9181 1.1269 25.2267
Lu-139 GDSC2 1.4643 5.1462 0.615 23.3047
NCI-H2170 GDSC2; CTRP2 1.5336 4.4145 1.3647 23.9689
SK-LU-1 GDSC2; CTRP2; CTRP1 1.5508 8.4825 -0.0438 28.7806
NCI-H2227 GDSC2 1.5741 4.0794 1.1648 19.7679
NCI-H2196 GDSC2; CTRP2 1.5762 6.3914 0.8219 25.7582
HCC2279 CTRP2 1.6766 6.9054 0.7344 25.7653
NCI-H1770 GDSC2 1.7129 3.9795 1.3509 18.1188
HCC2935 CTRP2; CTRP1 1.7318 5.9179 1.1617 24.1555
T3M-10 CTRP2; CTRP1 1.7543 7.1888 0.7094 25.6928
EMC-BAC-2 GDSC2 1.7632 5.5692 0.7323 21.4378
NCI-H740 GDSC2 1.8115 7.4478 -0.1039 25.5856
EBC-1 GDSC2; CTRP2 1.8392 5.0451 1.5463 22.3749
Lu-99A GDSC2 1.8937 6.1893 0.5748 21.7979
NCI-H1623 GDSC2; CTRP2 1.9169 6.3336 1.2092 23.3633
COR-L95 GDSC2; CTRP2 1.9505 6.5471 1.1649 23.4265
CAL-12T GDSC2; CTRP2; CTRP1 1.9825 7.4364 0.8484 24.5434
DMS 53 GDSC2; CTRP2 2.0579 6.7165 1.2139 22.9373
NCI-H2087 GDSC2; CTRP2 2.075 9.5642 0.0024 27.066
NCI-H2795 GDSC2 2.0822 11.6761 -1.9286 31.4619
SW1271 GDSC2; CTRP2 2.1218 8.0593 0.7229 24.5229
NCI-H1650 GDSC2; CTRP2 2.137 7.6097 0.9316 23.7376
RERF-LC-A1 CTRP2 2.1928 5.9662 1.6395 20.9792
NCI-H1435 GDSC2; CTRP2; CTRP1 2.2258 7.6222 1.0243 23.2253
HCC2108 CTRP2; CTRP1 2.2717 9.6118 0.1837 26.0049
DMS 114 GDSC2; CTRP2 2.3374 6.4719 1.6067 20.685
NCI-H2030 GDSC2; CTRP2; CTRP1 2.3453 7.9203 1.0194 22.9119
NCI-H1869 GDSC2; CTRP2 2.3716 8.5731 0.7508 23.7343
NCI-H2405 GDSC2; CTRP2; CTRP1 2.386 8.7768 0.6798 24.0139
NCI-H2066 GDSC2 2.4505 6.5597 0.9298 17.7407
NCI-H1838 GDSC2; CTRP2 2.5282 12.3779 -0.8843 28.4582
NCI-H1573 GDSC2; CTRP2; CTRP1 2.5716 8.7277 0.8889 22.7715
HCC366 GDSC2; CTRP2 2.7325 6.8881 1.8566 18.6393
LOU-NH91 GDSC2; CTRP2 2.7423 10.9537 0.0049 25.2719
COR-L105 GDSC2; CTRP2 2.8308 9.6692 0.7015 22.6935
Calu-3 GDSC2; CTRP2; CTRP1 2.8844 8.4015 1.3516 20.2407
ABC-1 GDSC2 3.0282 5.6918 1.8841 9.991
Lu-165 GDSC2 3.0427 9.8579 -0.1816 21.6664
HOP-62 GDSC2; CTRP2 3.0736 7.0351 2.1486 16.5931
NCI-H513 GDSC2 3.1203 10.3404 -0.3567 22.2361
NCI-H322 CTRP2 3.1463 6.7298 2.3549 15.5947
NCI-H1092 GDSC2; CTRP2 3.186 8.2664 1.7077 18.0272
KNS-62 GDSC2; CTRP2; CTRP1 3.1873 8.1283 1.7796 17.8196
NCI-H727 GDSC2; CTRP2 3.4124 8.1655 1.9782 16.3981
NCI-H1373 CTRP2 3.4201 9.2983 1.4482 18.4546
HCC78 GDSC2; CTRP2 3.4524 7.9645 2.1116 15.7691
NCI-H1793 GDSC2; CTRP2 3.4653 13.9144 -0.7668 25.8287
DMS 79 GDSC2 3.4808 7.6569 1.2854 12.3473
NCI-H2126 CTRP2 3.4962 7.7197 2.2687 15.0336
NCI-H1781 GDSC2; CTRP1 3.5729 10.7427 0.9002 25.2022
NCI-H345 GDSC2 3.589 8.0821 1.1606 12.79
NCI-H1693 GDSC2; CTRP2 3.6566 10.0979 1.2848 18.516
HCC1359 CTRP1 3.6893 7.8942 2.3842 29.0417
NCI-H2023 GDSC2; CTRP2; CTRP1 3.9371 9.5497 1.8216 15.8509
NCI-H2085 GDSC2; CTRP2 3.9594 13.023 0.1183 21.976
HCC1171 CTRP2 4.0568 19.6723 -3.108 30.0592
EKVX GDSC2; CTRP2 4.0789 8.2314 2.5888 12.3426
NCI-H2135 GDSC2 4.2469 7.2219 2.0786 5.5504
NCI-H2869 GDSC2 4.2564 7.353 2.022 5.8713
NCI-H2595 GDSC2 4.3569 8.6371 1.4697 8.97
NCI-H2291 GDSC2; CTRP2 4.4042 12.0891 0.9753 18.0013
NCI-H2803 GDSC2 4.4075 8.7079 1.4712 8.8438
NCI-H650 GDSC2; CTRP2; CTRP1 4.4139 14.7961 -0.3571 22.5534
NCI-H2373 GDSC2 4.4252 15.3935 -1.8209 24.3137
HOP-92 GDSC2; CTRP2 4.549 15.0759 -0.39 22.3105
NCI-H2342 GDSC2; CTRP2; CTRP1 4.8665 11.5887 1.6323 14.6056
RERF-LC-Ad2 CTRP2 4.8924 12.0738 1.4022 15.3755
NCI-H460 GDSC2; CTRP2; CTRP1 5.0111 7.7855 3.6556 5.9856
NCI-H2444 GDSC2; CTRP2 5.0401 9.0272 3.0494 8.3907
NCI-H2347 GDSC2 5.1533 12.3623 0.2221 14.0071
NCI-H2818 GDSC2 5.2224 15.7318 -1.3791 20.8177
NCI-H226 GDSC2; CTRP2 5.4572 10.046 2.8788 8.3282
HCC1195 CTRP2; CTRP1 5.6679 13.2926 1.4379 13.8176
NCI-H2722 GDSC2 5.674 15.4067 -0.8901 17.8842
NCI-H441 GDSC2; CTRP2; CTRP1 5.7205 16.4948 -0.1175 19.1894
NCI-H2369 GDSC2 5.7677 14.1035 -0.1918 14.6433
SW1573 GDSC2; CTRP2 5.8676 21.9321 -2.7237 25.8093
IA-LM GDSC2; CTRP2 5.9596 11.0315 2.7751 7.8956
NCI-H2591 GDSC2 6.0881 14.5471 -0.1863 13.951
BEN GDSC2; CTRP2 6.1258 7.7212 4.4635 0.9837
NCI-H1395 CTRP2 6.6301 12.6369 2.4747 8.0556
NCI-H1563 GDSC2; CTRP2 6.8271 18.2414 -0.1337 17.2183
Calu-1 CTRP2 7.3909 16.5648 1.1033 12.1162
RERF-LC-Ad1 CTRP2 8.601 30.8299 -5.0176 25.9276
Hs 888.Lu CTRP2 4.3351 15.2207 -0.6463 23.5339
⏷ Show the Full List of 221 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 -0.2813 2.6844 -0.4564 36.945
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 -1.6432 2.0631 -1.706 44.6844
H-STS CTRP2 0.7453 1.361 0.7453 28.6414
P-STS CTRP2 1.862 5.1688 1.5366 22.3403
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -0.6679 6.3005 -1.5728 40.1874
JHOC-5 CTRP1 -5.4377 17.9619 -11.3755 65.731
COV362 CTRP2; CTRP1 -3.5241 5.365 -4.3933 76.6841
Caov-4 GDSC2 -1.0563 2.967 -1.3641 44.6956
Caov-3 GDSC2; CTRP2; CTRP1 -0.9758 4.9531 -1.4984 41.3577
RMUG-S CTRP1 -0.8619 4.563 -1.2743 70.0759
COV434 CTRP2; CTRP1 -0.7932 4.8478 -1.2712 40.1414
OVCAR-8 GDSC2; CTRP2; CTRP1 -0.7557 0.7721 -0.756 38.7013
SNU-119 CTRP2 -0.6824 3.7021 -0.8968 38.7598
JHOS-4 GDSC2; CTRP1 -0.5229 2.9136 -0.6087 47.807
A2780 GDSC2; CTRP2; CTRP1 -0.4844 2.9928 -0.5769 37.1807
ONCO-DG-1 CTRP2 -0.3513 2.6635 -0.4041 36.1162
DOV13 GDSC2 -0.3486 2.9652 -0.5924 37.8753
OVCAR-3 GDSC2 -0.1898 3.2199 -0.4831 36.5403
OC 314 GDSC2; CTRP2 0.0501 2.7525 0.0084 33.4104
OVKATE GDSC2; CTRP1 0.0643 4.4369 -0.2355 43.4361
ES-2 GDSC2 0.1383 4.8159 -0.6502 35.4026
IGROV-1 GDSC2; CTRP2; CTRP1 0.1627 5.7938 -0.5018 34.6171
TYK-nu GDSC2; CTRP2; CTRP1 0.2902 4.5863 -0.0243 32.7592
SNU-8 CTRP2 0.4173 2.0918 0.4138 30.838
MCAS CTRP2 0.4686 2.3814 0.4596 30.5145
OVCAR-4 GDSC2; CTRP2; CTRP1 0.568 3.7545 0.4425 30.3099
OV56 GDSC2; CTRP2 1.0006 3.0652 0.9756 27.0242
TOV-112D GDSC2; CTRP2 1.0252 6.2042 0.2944 29.2514
RMG-I GDSC2; CTRP2; CTRP1 1.1387 7.6375 -0.1218 30.2745
OAW28 GDSC2; CTRP2 1.1922 7.0449 0.1642 29.1495
TOV-21G GDSC2; CTRP2 1.2859 6.2487 0.5604 27.5466
OVK18 GDSC2; CTRP2; CTRP1 1.4614 4.66 1.2341 24.726
OVTOKO GDSC2; CTRP2 1.7449 10.6857 -0.8432 30.4674
FU-OV-1 GDSC2; CTRP2 1.8015 6.6208 0.9775 24.5373
JHOM-1 CTRP2; CTRP1 1.8524 6.0306 1.2532 23.4665
OVCAR-5 GDSC2; CTRP2 1.8726 15.6673 -3.0968 34.9693
OV7 CTRP2; CTRP1 1.9362 6.956 0.9949 24.1538
SK-OV-3 GDSC2; CTRP2; CTRP1 1.9506 8.5845 0.3231 26.4409
OVSAHO CTRP2 2.035 7.5905 0.8335 24.3766
HEY A8 CTRP2; CTRP1 2.1855 6.1923 1.5541 21.391
EFO-21 GDSC2; CTRP2; CTRP1 2.2684 7.4295 1.1502 22.6474
COV644 CTRP2; CTRP1 2.6213 9.8309 0.4275 24.2564
OVISE GDSC2; CTRP2 2.8323 5.8045 2.3871 16.341
OAW42 GDSC2; CTRP2; CTRP1 2.8808 9.6145 0.7833 22.3425
EFO-27 GDSC2; CTRP2; CTRP1 2.9932 8.6234 1.3578 19.9367
OV-90 GDSC2; CTRP2; CTRP1 2.9977 8.3573 1.4851 19.4408
ES2 CTRP2 3.3919 8.6228 1.7429 17.377
COV318 CTRP1 3.5164 12.2716 0.0982 38.6396
Kuramochi GDSC2; CTRP2 4.2474 12.9157 0.4263 20.3003
OVMANA CTRP1 5.2909 9.2018 3.1774 15.5877
SNU-840 CTRP2; CTRP1 5.4591 18.076 -1.1192 22.6631
JHOS-2 GDSC2; CTRP2 5.6772 15.0565 0.5554 16.9633
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 -0.4363 8.8541 -2.2816 40.5126
EW-8 GDSC2 -2.7802 -0.8901 -2.7816 61.1461
Tm87-16 CTRP2 -2.5415 22.9297 -10.8037 50.1685
STS-0421 GDSC2 -1.6996 5.4175 -2.8454 50.253
Rh41 GDSC2; CTRP2 -1.4707 1.1867 -1.4817 43.4341
Rh30 GDSC2 -1.0892 0.6658 -1.0956 44.2905
G-401 GDSC2; CTRP2; CTRP1 -0.2999 2.5208 -0.3388 35.7925
GCT GDSC2; CTRP2 -0.116 3.3296 -0.2286 34.7413
Hs 633.T GDSC2 -0.0824 2.9822 -0.3063 35.205
TE 617.T CTRP2 0.0102 3.5389 -0.1238 33.9726
TE 441.T GDSC2; CTRP2 0.02 3.3401 -0.0849 33.8152
SK-UT-1 GDSC2; CTRP2 0.0242 4.1818 -0.2251 34.2389
SW982 GDSC2; CTRP2 0.3305 6.6929 -0.6286 34.3196
RD GDSC2; CTRP2 0.6479 5.8742 -0.0034 31.4257
Hs 729.T CTRP2 0.7111 6.4092 -0.1169 31.5672
HT-1080 GDSC2; CTRP2; CTRP1 0.9214 5.4905 0.4187 29.2383
KYM-1 GDSC2; CTRP2 1.004 7.0954 -0.0559 30.4338
BT-16 CTRP2 1.0826 3.5837 1.0146 26.6235
RKN GDSC2; CTRP2; CTRP1 1.7668 4.5352 1.5944 22.504
TTC-709 CTRP2 1.8003 7.5774 0.5937 25.8907
MES-SA GDSC2; CTRP2 1.8126 7.8291 0.5011 26.1718
G-402 GDSC2; CTRP2 1.8993 6.6014 1.0895 23.8487
VA-ES-BJ GDSC2 1.964 7.2023 0.1596 23.7157
A-204 GDSC2; CTRP2 2.1633 7.3178 1.0818 23.1198
BT-12 CTRP2 2.3822 5.4281 2.0259 18.9974
SW872 GDSC2 2.6932 6.5456 1.1602 15.5465
SK-LMS-1 GDSC2; CTRP2 2.7218 8.1716 1.286 20.8399
Rh18 CTRP2 3.5688 10.5331 0.9906 19.8257
SW684 GDSC2 3.7363 7.8073 1.4145 10.856
MFH-ino GDSC2 4.4512 10.3792 0.6845 13.2493
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 5.1998 10.8165 2.2868 11.2496
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC2; CTRP2; CTRP1 -1.7098 2.0292 -1.7724 45.1724
NCI-H28 GDSC2; CTRP2; CTRP1 0.5641 7.0657 -0.5105 33.2622
MPP 89 GDSC2; CTRP2 1.1349 5.8751 0.5252 28.1363
NCI-H2452 GDSC2; CTRP2 2.6623 8.1359 1.2417 21.1636
NCI-H2052 GDSC2; CTRP2; CTRP1 4.4837 12.7137 0.7422 18.7466
ACC-MESO-1 CTRP2 4.6904 8.277 3.1244 8.7795
IST-Mes1 GDSC2; CTRP2 5.7265 13.8937 1.1745 14.636
JL-1 CTRP2 8.3793 14.8522 2.5622 5.4456
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2; CTRP2 0.4736 4.4817 0.1978 31.3651
VCaP GDSC2; CTRP2 2.521 7.77 1.2597 21.4755
DU145 GDSC2; CTRP2 3.0594 8.1625 1.6296 18.6522
22Rv1 GDSC2; CTRP2 3.146 8.996 1.3268 19.5945
PC-3 GDSC2 3.7218 8.6668 0.9749 13.5128
PaCa-3 CTRP2; CTRP1 3.8823 7.4155 2.7984 12.033
NCI-H660 GDSC2 4.0654 8.0614 1.5396 9.248
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -0.5881 4.2782 -0.9116 38.4292
A-253 GDSC2; CTRP2 4.1065 11.601 0.9551 18.7251
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 -0.9347 0.3579 -0.9356 42.7197
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-StC-K140 CTRP2 -2.3638 4.6995 -2.9488 49.4684
SK-GT-2 GDSC2 -1.7649 1.435 -1.8508 50.9801
TGBC11TKB GDSC2 -1.3909 0.5162 -1.3984 47.3108
HSC-39 GDSC2 -1.2387 0.6874 -1.2483 45.7963
SNU-601 CTRP2 -1.1739 4.0371 -1.4957 42.1522
SCH GDSC2 -1.083 3.3503 -1.4931 45.118
IM95 GDSC2; CTRP2 -1.0826 6.3834 -2.0505 42.6723
GSS CTRP2 -0.9449 0.8071 -0.9457 39.9041
NCI-N87 GDSC2; CTRP2 -0.5774 5.2715 -1.1543 38.9649
AGS GDSC2; CTRP1 -0.5622 2.5486 -0.6147 48.0978
SNU-16 GDSC2; CTRP2 -0.4678 0.9694 -0.4681 36.7238
HGC-27 GDSC2; CTRP2 -0.3117 2.2763 -0.3364 35.7638
ECC10 GDSC2; CTRP2 -0.2978 4.5529 -0.6593 36.6606
RERF-GC-1B GDSC2 -0.2935 3.0299 -0.548 37.3856
SNU-5 GDSC2; CTRP2 -0.094 2.6107 -0.1313 34.3555
HuG1-N CTRP2 0.006 4.8325 -0.3978 34.8179
SNU-1 GDSC2; CTRP2 0.0909 3.4465 -0.0238 33.3762
OCUM-1 GDSC2; CTRP2 0.1504 26.4676 -9.9767 44.7406
TMK-1 GDSC2 0.237 1.5825 0.2291 30.9974
23132/87 GDSC2; CTRP2 0.3635 2.9233 0.3223 31.3222
SNU-216 CTRP2 0.5448 4.3702 0.3002 30.7927
RF-48 GDSC2 0.5479 4.1772 0.0243 30.4601
NUGC-3 GDSC2; CTRP2 0.5892 5.9859 -0.104 31.9315
SH-10-TC CTRP2; CTRP1 0.7817 3.3172 0.7264 28.6531
ECC12 GDSC2; CTRP2 0.8426 2.1767 0.8414 27.9969
MKN1 GDSC2; CTRP2 1.0794 4.7122 0.8033 27.3595
MKN28 GDSC2 1.3705 6.5024 -0.0881 27.2799
SNU-620 CTRP2 1.7844 3.4218 1.7659 21.7808
GCIY GDSC2 1.8037 5.0478 1.0071 19.717
Hs 746.T GDSC2; CTRP2 1.8326 8.1874 0.3689 26.5602
GSU CTRP2 1.9706 4.3706 1.8469 20.9014
Fu97 GDSC2; CTRP2; CTRP1 2.0957 10.4832 -0.395 28.2834
NUGC-4 GDSC2; CTRP2; CTRP1 2.2178 8.3235 0.7116 24.3638
MKN74 CTRP2; CTRP1 2.3461 8.796 0.6309 24.2933
MKN7 GDSC2; CTRP2; CTRP1 3.045 9.2717 1.1054 20.7516
SNU-668 CTRP2 3.0971 11.408 0.123 23.9944
SNU-719 CTRP2 4.123 10.8823 1.326 17.2949
KE-39 CTRP2 4.5366 11.346 1.461 15.8812
KATO III GDSC2; CTRP2 4.5651 9.8732 2.2198 12.7923
MKN45 GDSC2; CTRP2 5.6545 8.6461 3.7232 4.4808
LMSU CTRP2 6.1273 13.0516 1.9036 11.1269
SNG-M GDSC2; CTRP2; CTRP1 1.2024 4.627 0.9597 26.4987
SNU-685 CTRP2 1.8328 7.7102 0.5722 25.8704
SNU-1077 CTRP2 2.3208 7.6164 1.1197 22.5415
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC2 -0.9137 0.3921 -0.9147 42.5093
FTC-238 CTRP2 -0.578 1.6228 -0.5853 37.481
IHH-4 GDSC2 -0.1398 3.6522 -0.5511 36.5299
HTC-C3 GDSC2 0.3569 3.7114 -0.0281 31.6519
ML-1 [Human leukemia] GDSC2; CTRP2 0.6973 8.2554 -0.8438 33.6545
B-CPAP GDSC2; CTRP2 1.1015 4.7165 0.8263 27.2102
BHT-101 GDSC2; CTRP2 2.1131 6.8819 1.207 22.8047
K5 GDSC2 2.1785 7.4624 0.2357 22.5319
TT GDSC2; CTRP2 2.7843 6.7173 1.9817 18.0181
8305C GDSC2; CTRP2 2.8001 10.5291 0.2635 24.2788
ASH-3 GDSC2 2.9435 5.682 1.8134 10.7059
FTC-133 GDSC2; CTRP2 3.3359 10.0197 1.0208 20.2729
8505C GDSC2; CTRP2 3.5287 7.7244 2.2987 14.8328
SW579 CTRP2 3.9299 11.9401 0.6287 20.2989
TT2609-C02 GDSC2; CTRP2 4.1874 13.2016 0.2313 21.0941
WRO GDSC2 4.7738 11.8835 0.1826 15.0935
CGTH-W-1 GDSC2; CTRP2 5.7835 8.8034 3.7396 4.2119
CAL-62 GDSC2; CTRP2 6.4787 7.7122 4.6339 0.2799
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-25 GDSC2; CTRP2 -3.0503 10.8884 -5.8643 52.0846
BICR 10 GDSC2 -1.5045 2.3411 -1.7136 48.6056
PCI-06A GDSC2 -1.178 1.2443 -1.2146 45.265
JHU-011 GDSC2 -1.1643 0.9061 -1.1803 45.0725
PCI-15A GDSC2 -0.883 1.6578 -0.9424 42.4195
BB30-HNC GDSC2 -0.8291 1.0563 -0.8426 41.7143
SNU-1214 CTRP2 -0.8046 4.7148 -1.2519 40.0926
BB49-HNC GDSC2 -0.7993 4.6461 -1.596 43.4264
HO-1-u-1 GDSC2 -0.7515 2.3445 -0.8998 41.4267
KON GDSC2 -0.6926 1.6554 -0.7414 40.493
NCI-H3118 GDSC2 -0.6436 2.3258 -0.7802 40.3383
SAS GDSC2 -0.5346 3.6444 -0.9791 40.3068
Ca9-22 GDSC2 -0.3295 2.1339 -0.4127 37.0276
YD-10B CTRP2 -0.3071 3.6543 -0.4835 36.1979
CAL-33 GDSC2; CTRP2 -0.2637 2.9328 -0.3375 35.6
BICR 6 CTRP2 -0.0657 4.4324 -0.378 35.0161
KOSC-2 GDSC2 -0.0577 3.0707 -0.3009 35.0477
OSC-19 GDSC2 0.1836 2.289 0.1137 31.8429
PCI-04B GDSC2 0.2921 4.4972 -0.3664 33.4856
DOK GDSC2 0.3003 5.6119 -0.7948 35.0989
SNU-1076 CTRP2 0.3771 4.9152 -0.0144 32.3683
BICR 16 CTRP2 0.4102 3.8753 0.2514 31.4013
CAL-27 GDSC2; CTRP2 0.4389 4.2677 0.207 31.451
PE/CA-PJ49 CTRP2 0.571 3.8026 0.4368 30.2522
HO-1-N-1 GDSC2 0.5744 4.6547 -0.1227 31.0172
PE/CA-PJ34 (clone C12) CTRP2 0.6331 5.4096 0.1257 31.067
JHU-029 GDSC2 0.6914 3.259 0.4681 27.5498
SKN-3 GDSC2 0.784 6.5315 -0.6918 32.4126
BICR 22 GDSC2; CTRP2 0.8106 5.1007 0.4085 29.5624
LB771-HNC GDSC2 0.9333 7.3147 -0.8981 32.5136
HSC-2 GDSC2; CTRP2; CTRP1 0.9898 4.0176 0.853 27.5458
UPCI-SCC-090 GDSC2 1.0249 5.3809 0.0589 28.0709
PE/CA-PJ15 GDSC2; CTRP2 1.0635 6.0988 0.3723 28.8731
BICR 56 CTRP2 1.0805 6.6805 0.1828 29.4392
JHU-022 GDSC2 1.1597 7.9052 -0.9512 31.7407
SNU-1066 CTRP2 1.6096 8.9756 -0.2044 29.037
BHY GDSC2; CTRP2 1.7461 9.7311 -0.4041 29.2347
SCC-9 GDSC2; CTRP2; CTRP1 1.854 8.3292 0.3354 26.6761
BICR 18 CTRP2 2.0489 6.8339 1.158 23.1675
SCC-4 GDSC2; CTRP2 2.3362 7.6147 1.1363 22.438
Detroit 562 GDSC2; CTRP2 2.3788 5.8597 1.878 19.554
YD-8 CTRP2 2.3846 9.8921 0.1589 25.7156
BICR 78 GDSC2 2.4174 7.1257 0.6221 19.6082
SNU-46 CTRP2 2.4331 14.1859 -1.8507 31.1034
PCI-30 GDSC2 2.4388 8.9115 -0.2391 23.9281
SCC-15 GDSC2 2.465 6.9892 0.7329 18.8199
SAT [Human HNSCC] GDSC2 2.6039 12.7292 -1.9927 29.9635
PE/CA-PJ41 (clone D2) CTRP2 2.6901 9.3665 0.7054 23.0447
HSC-4 GDSC2; CTRP2 2.788 9.0432 0.9528 21.9006
BICR 31 GDSC2; CTRP2 3.2874 10.8707 0.5629 22.0385
OSC-20 GDSC2 3.4341 9.1365 0.5076 16.9643
HSC-3 GDSC2; CTRP2 3.8782 9.1862 1.9362 15.4526
FaDu GDSC2; CTRP2 4.3593 13.1679 0.3985 20.1531
SNU-1041 CTRP2 4.553 14.7335 -0.2155 21.7599
SNU-899 CTRP2 4.9651 13.7351 0.6327 18.0736
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 -1.9046 1.2648 -1.9278 46.3369
5637 GDSC2; CTRP2; CTRP1 -0.8395 1.3706 -0.8452 39.2763
BC-3C CTRP2 -0.7 4.3438 -1.0482 39.206
BFTC-905 GDSC2 0.0098 1.9675 -0.0325 33.4476
647V GDSC2; CTRP2 0.2584 3.2355 0.1814 32.1404
HT-1376 GDSC2; CTRP2; CTRP1 0.5129 4.9947 0.1151 31.5657
SCaBER CTRP2 0.5848 4.8738 0.223 30.9131
TCCSUP GDSC2; CTRP2 0.6127 4.7657 0.2811 30.6307
UM-UC-1 CTRP2 0.854 5.0682 0.4647 29.2342
RT-112 GDSC2; CTRP2 1.0628 4.4717 0.8411 27.2825
RT-4 GDSC2; CTRP2; CTRP1 1.2006 5.2304 0.8001 27.0574
639V GDSC2; CTRP2 1.2378 3.2835 1.2071 25.4631
VM-CUB-1 CTRP2 1.4851 6.8887 0.5369 27.0187
J82 GDSC2; CTRP2 1.5264 6.9051 0.5746 26.7659
KMBC-2 CTRP2; CTRP1 2.0799 6.774 1.2194 22.9266
SW1710 GDSC2; CTRP2 2.9121 7.2334 1.8961 18.0037
SW780 GDSC2 3.4473 5.7932 2.1892 6.8149
HT-1197 GDSC2; CTRP2 4.1168 12.7878 0.3749 20.7635
UM-UC-3 GDSC2; CTRP2; CTRP1 4.3506 11.1394 1.41 16.5468
T24 GDSC2; CTRP2 4.4486 10.5558 1.7776 14.8231
CAL-29 GDSC2; CTRP2 5.3632 13.6332 1.0127 15.9177
253J-BV CTRP2 6.5507 7.9515 4.5732 0.3822
KU-19-19 GDSC2; CTRP2 6.8079 12.2978 2.7613 6.6593
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
C-33 A GDSC2 -1.3693 0.7832 -1.3855 47.1132
OV17R GDSC2 -1.156 2.3277 -1.3338 45.3614
OVCA433 GDSC2 -1.0967 1.4924 -1.1508 44.5095
C-4-I GDSC2 -1.0956 2.4876 -1.2995 44.8493
NCC-IT GDSC2 -1.0077 0.9613 -1.0219 43.503
UWB1.289 GDSC2 -1.0075 1.8986 -1.104 43.7533
SW954 GDSC2 -1.0073 1.0706 -1.0266 43.517
TC-YIK GDSC2 -0.7456 1.8971 -0.8247 41.1324
Ca Ski GDSC2 -0.6439 2.8542 -0.888 40.7044
NEC8 GDSC2 -0.5225 0.5792 -0.523 38.5818
JAR GDSC2 -0.4983 1.5424 -0.5282 38.4751
HeLa GDSC2; CTRP2 -0.3527 1.0007 -0.3529 35.9566
CAL-39 GDSC2 -0.3326 3.522 -0.7228 38.264
PA-1 GDSC2 -0.2429 2.872 -0.4555 36.7251
OMC-1 [Human cervical carcinoma] GDSC2 0.1459 4.0464 -0.366 34.2401
BPH-1 GDSC2 0.2668 3.235 0.0111 31.9213
ACC-OV7 GDSC2 0.2863 3.3575 -0.0008 31.8788
OVMIU GDSC2 0.2987 4.8117 -0.4772 33.9068
PWR-1E GDSC2 0.3015 2.0187 0.2694 30.4717
ME-180 GDSC2 0.3269 4.8343 -0.4557 33.6774
NT2-D1 GDSC2 0.4015 4.1636 -0.1292 31.8967
MS751 GDSC2 0.5614 2.6187 0.4681 28.1778
JEG-3 GDSC2 0.7377 3.0536 0.5702 26.7972
SiSo GDSC2 0.8122 2.8734 0.6911 25.8092
JHOS-3 GDSC2 0.9296 4.4853 0.3216 27.1931
KGN GDSC2 1.1508 8.7828 -1.3771 33.2161
LB831-BLC GDSC2 1.2223 4.1851 0.748 23.6183
SKG-IIIa GDSC2 1.3454 6.5172 -0.1199 27.5332
HEY GDSC2 1.3913 5.8845 0.2143 25.7183
HT-3 GDSC2 1.4076 4.0865 0.9835 21.5061
OVCA420 GDSC2 1.4343 6.7777 -0.1524 27.3149
PEO1 GDSC2 1.6174 6.7511 0.04 25.657
HEC-1 GDSC2 1.6577 5.465 0.6728 22.192
DSH1 GDSC2 1.8767 7.7138 -0.1701 25.6464
DoTc2 4510 GDSC2 2.4079 5.8824 1.2182 16.1871
SKN GDSC2 2.4481 8.2223 0.1102 22.2098
SW756 GDSC2 2.8784 9.5747 -0.1814 22.1891
SiHa GDSC2 3.2213 8.1839 0.8066 15.9349
SW962 GDSC2 4.1104 7.6393 1.7799 7.6762
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7702).
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 A novel c-Met inhibitor, MK8033, synergizes with carboplatin plus paclitaxel to inhibit ovarian cancer cell growth. Oncol Rep. 2013 May;29(5):2011-8.
4 Functional kinomics identifies candidate therapeutic targets in head and neck cancer. Clin Cancer Res. 2014 Aug 15;20(16):4274-88. doi: 10.1158/1078-0432.CCR-13-2858.