Details of the Drug

General Information of Drug (ID: DM3ZW6A)

Drug Name
VAN-10-4-eluting stent
Synonyms INC-105-eluting stent, Inncardio/University of Strathclyde; VAN-10-4-eluting stent, University of Strathclyde; Marigold compound (drug-eluting stent, restenosis), Inncardio/University of Strathclyde
Indication
Disease Entry ICD 11 Status REF
Artery stenosis BD52 Phase 1 [1]
Cross-matching ID
TTD ID
D08KNG

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Extracellular signal-regulated kinase 1 (ERK1) TT1MG9E MK03_HUMAN Inhibitor [2]
Extracellular signal-regulated kinase 2 (ERK2) TT4TQBX MK01_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Artery stenosis
ICD Disease Classification BD52
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Extracellular signal-regulated kinase 2 (ERK2) DTT MAPK1 6.78E-05 1.12 2.73
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Drug-Eluting Stent for High Risk Patients. University of Strathclyde Glasgow. 2015
2 WO patent application no. 2013,1850,32, Nanotherapeutics for drug targeting.