General Information of Drug (ID: DM450XS)

Drug Name
BAY 2253651
Indication
Disease Entry ICD 11 Status REF
Obstructive sleep apnea 7A41 Phase 2 [1]
Drug Type
Small molecular drug
Cross-matching ID
TTD ID
D85NEG

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TWIK-related acid-sensitive potassium channel 1 (TASK1) TTGR91N KCNK3_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03603678) Obstructive Sleep Apnea (OSA) Treated With a Potassium Channel Inhibitor (SANDMAN). U.S. National Institutes of Health.
2 Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.