Details of the Drug

General Information of Drug (ID: DM45JMT)

Drug Name
Peptide analog 61
Synonyms PMID26118988-Compound-16
Drug Type
Peptide
Sequence
AlaChaCysCysGlnGlnOctGProPro4NHCOPheSerThr
Cross-matching ID
TTD ID
D09ZUJ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cathepsin G (CTSG) TTQAJF1 CATG_HUMAN Inhibitor [1]
Neutrophil elastase (NE) TTPLTSQ ELNE_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cathepsin G (CTSG) DTT CTSG 8.23E-01 0.23 0.26
Cathepsin G (CTSG) DTT CTSG 5.14E-01 0.05 0.19
Neutrophil elastase (NE) DTT ELANE 9.42E-01 0.02 0.07
Neutrophil elastase (NE) DTT ELANE 1.43E-02 0.05 0.2
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Neutrophil elastase inhibitors: a patent review and potential applications for inflammatory lung diseases (2010 - 2014).Expert Opin Ther Pat. 2015;25(10):1145-58.