Details of the Drug

General Information of Drug (ID: DM4HYMS)

Drug Name
ABT-888
Synonyms
Veliparib; 912444-00-9; ABT-888; ABT 888; ABT-888 (Veliparib); Veliparib (ABT-888); ABT888; UNII-01O4K0631N; 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide; CHEBI:62880; 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide; (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide; 01O4K0631N; 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-; (2r)-2-(7-Carbamoyl-1h-Benzimidazol-2-Yl)-2-Methylpyrrolidinium; Veliparib dihydrochloride
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Phase 3 [1]
Epithelial ovarian cancer 2B5D Phase 3 [2]
Non-small-cell lung cancer 2C25.Y Phase 3 [3]
Ovarian cancer 2C73 Phase 3 [3]
Melanoma 2C30 Phase 2 [2]
ATC Code
L01XK05: ABT-888
L01XK: Poly (ADP-ribose) polymerase (PARP) inhibitors
L01X: OTHER ANTINEOPLASTIC AGENTS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 317.21
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 2
Hydrogen Bond Donor Count 5
Hydrogen Bond Acceptor Count 3
Chemical Identifiers
Formula
C13H18Cl2N4O
IUPAC Name
2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide;dihydrochloride
Canonical SMILES
C[C@@]1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N.Cl.Cl
InChI
InChI=1S/C13H16N4O.2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12;;/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17);2*1H/t13-;;/m1../s1
InChIKey
DSBSVDCHFMEYBX-FFXKMJQXSA-N
Cross-matching ID
PubChem CID
45480520
CAS Number
912445-05-7
UNII
01O4K0631N
DrugBank ID
DB07232
TTD ID
D0Q7UD
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Poly [ADP-ribose] polymerase (PARP) TTEBCY8 NOUNIPROTAC Modulator [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 4.4646 6.5602 2.5269 2.5237
EW-22 GDSC1; GDSC2 3.8064 5.5517 2.5804 3.4597
MHH-ES-1 GDSC1; GDSC2; CTRP2 4.1992 6.2051 3.6665 7.6607
ES7 GDSC1; GDSC2 4.3949 6.5546 2.4881 2.8547
ES1 GDSC1; GDSC2 4.4731 6.5649 2.5296 2.4951
CHSA8926 GDSC1; GDSC2 4.6087 6.6538 2.5668 2.0911
A-673 GDSC1; GDSC2; CTRP2 4.6798 7.0465 3.7253 6.2909
CADO-ES1 GDSC1; GDSC2; CTRP2 4.8956 6.67 4.1044 4.248
EW-3 GDSC1; GDSC2 4.9865 11.235 0.6521 12.1601
ES5 GDSC1; GDSC2 4.998 7.917 2.2252 3.3222
U2OS GDSC1; GDSC2; CTRP2 5.0259 6.5701 4.2661 3.3075
EW-24 GDSC1; GDSC2 5.0433 6.8616 2.6982 0.9776
EW-12 GDSC2 5.1091 7.2961 2.5526 1.5344
HuO-3N1 GDSC1; GDSC2 5.2449 7.886 2.3731 2.2183
EW-13 GDSC1; GDSC2 5.278 7.5268 2.5395 1.4167
SK-N-MC CTRP2 5.288 6.3434 4.585 1.5083
TC-71 GDSC1; GDSC2 5.5185 7.1282 2.7961 0.3578
ES8 GDSC1; GDSC2 5.5542 8.2634 2.3704 1.8739
ES4 GDSC1; GDSC2 5.572 7.5941 2.6449 0.7682
EW-16 GDSC1; GDSC2 5.6179 7.6529 2.642 0.7481
ES6 GDSC1; GDSC2 5.7194 7.7311 2.6545 0.6465
NOS-1 [Human HNSCC] GDSC1; GDSC2 5.802 7.8037 2.661 0.5819
TC71 CTRP2 5.8144 7.5088 4.3794 1.6117
SK-PN-DW GDSC1; GDSC2 5.8431 7.39 2.8242 0.1941
EW-1 GDSC1; GDSC2 5.8562 7.6203 2.7485 0.3359
EW-7 GDSC1; GDSC2 5.8757 11.8911 0.9326 8.8326
U-CH2 GDSC2 5.931 7.6108 2.7795 0.2487
CAL-72 GDSC1; GDSC2 5.9876 7.8029 2.733 0.3228
HuO9 GDSC1; GDSC2 6.0173 8.1619 2.615 0.6002
EW-18 GDSC1; GDSC2 6.0206 8.0301 2.6644 0.4678
NY GDSC1; GDSC2 6.1778 8.5314 2.5429 0.7224
CHSA0108 GDSC1; GDSC2 6.2965 8.325 2.6638 0.3622
Hs 822.T CTRP2 6.4263 7.2416 4.7827 0.059
SW1353 CTRP2 6.5125 10.4826 3.4299 4.4195
SK-ES-1 GDSC1; GDSC2; CTRP2 6.6043 9.0302 4.1523 1.6027
EW-11 GDSC1; GDSC2 6.6641 9.4445 2.4005 0.8739
H-EMC-SS GDSC1; GDSC2 6.8343 9.0732 2.5995 0.3205
CHSA0011 GDSC1; GDSC2 6.9703 8.913 2.702 0.1421
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 7.0754 10.2931 3.8569 2.176
CAL-78 GDSC1; GDSC2; CTRP2 7.2431 8.5697 4.618 0.1041
HOS GDSC1; GDSC2; CTRP2 7.286 8.6212 4.6156 0.1
SaOS-2 GDSC1; GDSC2; CTRP2 7.3157 8.8088 4.5615 0.1573
SJSA-1 GDSC1; GDSC2; CTRP2 7.3725 9.2216 4.435 0.3419
MG-63 GDSC1; GDSC2; CTRP2 7.3799 11.2129 3.6204 2.7052
Hs 888.T CTRP2 7.3988 9.0909 4.4927 0.2357
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 220 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 5.4664 7.8794 3.9613 3.8
MEC1 CTRP2 6.2531 7.6715 4.5491 0.6151
JM1 GDSC1; GDSC2; CTRP2 5.4664 7.555 4.121 3.1388
U-698-M GDSC1; GDSC2 3.5373 5.2235 2.5441 4.3332
MY-M12 GDSC1; GDSC2 3.5466 5.4586 2.4346 4.9976
DoHH2 GDSC1; GDSC2 3.683 5.4883 2.523 4.1007
NKM-1 GDSC1; GDSC2 3.743 10.3013 0.1767 17.8141
MHH-CALL-2 GDSC1 3.8493 5.6573 1.6896 1.4935
Farage GDSC1; GDSC2 3.8787 5.9076 2.4586 4.0439
697 GDSC1; GDSC2; CTRP2 3.9646 6.4196 3.3324 9.5938
SUP-B15 GDSC1; GDSC2; CTRP2 4.0693 6.5699 3.3697 9.1792
RC-K8 GDSC1 4.0714 5.4978 1.8504 0.5305
GR-ST GDSC1; GDSC2 4.2627 8.3795 1.5279 8.8429
Loucy GDSC1; GDSC2 4.2827 6.2602 2.5553 2.6695
Karpas-1106P GDSC1; GDSC2 4.2991 6.2188 2.5841 2.4791
KOPN-8 GDSC1; GDSC2 4.311 5.9081 2.7304 1.6655
MOLT-4 GDSC1; GDSC2 4.3197 6.3479 2.5375 2.7058
MHH-CALL-3 CTRP2 4.3393 9.218 2.3443 12.7643
EB2 GDSC1; GDSC2 4.3461 5.9205 2.7442 1.5437
SU-DHL-16 GDSC1; GDSC2 4.3738 8.5331 1.5324 8.5574
YT GDSC1; GDSC2 4.3888 8.3989 1.6082 8.0699
SUP-B8 GDSC1; GDSC2 4.4561 6.2862 2.6442 1.9065
Sc-1 GDSC1 4.4856 5.833 1.8879 0.2218
Kasumi-2 CTRP2 4.5003 6.2891 3.9258 5.8692
CCRF-CEM GDSC1; GDSC2 4.5207 7.6335 2.0646 5.0702
WSU-NHL GDSC1 4.5369 6.1436 1.7976 0.4316
HC-1 GDSC1; GDSC2 4.5369 6.1429 2.7491 1.2741
SU-DHL-5 GDSC1; GDSC2; CTRP1 4.5478 6.8779 3.6948 8.7258
VAL GDSC1; GDSC2 4.5708 6.7358 2.5092 2.4527
KMOE-2 GDSC1; GDSC2 4.5782 6.9875 2.4001 3.0379
Granta-519 GDSC1; GDSC2; CTRP2 4.6268 6.5536 3.9187 5.6044
CTB-1 GDSC1; GDSC2 4.6513 7.8253 2.0582 4.8552
SUP-M2 GDSC1; GDSC2; CTRP2 4.6872 6.4998 4.0011 5.127
CTV-1 GDSC1; GDSC2 4.6895 8.5484 1.7417 6.6301
P30/OHK GDSC1; GDSC2 4.7956 6.537 2.7131 1.1515
ME1 GDSC1; GDSC2 4.821 6.0643 2.9101 0.3879
OCI-Ly7 GDSC1; GDSC2 4.8225 6.1658 2.8725 0.5055
BC-1 GDSC1; GDSC2 4.8281 6.9996 2.5347 1.9546
SCC-3 GDSC2 4.8362 6.2768 2.8357 0.6228
WIL2 NS GDSC1; GDSC2 4.8443 6.9267 2.5744 1.739
OCI-AML-2 GDSC1; GDSC2; CTRP2 4.8757 7.5069 3.6699 6.1117
P32/ISH GDSC1; GDSC2 4.8856 6.0543 2.9394 0.275
ARH-77 GDSC1; GDSC2 4.9223 7.0797 2.5496 1.7631
Ramos.2G6.4C10 GDSC1; GDSC2 4.9385 8.7379 1.8134 5.7258
TK [Human B-cell lymphoma] GDSC1; GDSC2 4.946 6.5406 2.7812 0.7382
QIMR-WIL GDSC1; GDSC2 4.9484 8.0104 2.1544 3.7864
CRO-AP2 GDSC1; GDSC2 4.9541 6.662 2.7369 0.9012
Jiyoye GDSC1; GDSC2 4.9723 8.6753 1.8638 5.3754
NU-DHL-1 CTRP2 5.0079 9.0313 3.0205 8.5744
Karpas-45 GDSC1; GDSC2 5.0091 7.8844 2.246 3.1935
HAL-01 GDSC1; GDSC2 5.0402 8.4849 1.993 4.5272
ML-2 GDSC1; GDSC2 5.095 10.4197 1.1198 9.3612
BE-13 GDSC1; GDSC2 5.1247 7.7871 2.3524 2.4754
TUR GDSC1; GDSC2 5.1302 6.6727 2.8091 0.5166
BC-3 GDSC2 5.1315 6.47 2.8842 0.3058
Karpas-231 GDSC1; GDSC2 5.1681 6.259 2.9718 0.1195
MHH-PREB-1 GDSC1; GDSC2 5.1945 7.3441 2.5742 1.3504
NK-92MI GDSC2 5.2108 7.0454 2.7008 0.8299
MN-60 GDSC1; GDSC2 5.2116 8.8381 1.9342 4.5636
GA-10 GDSC1; GDSC2; CTRP2 5.2141 6.4922 4.4566 2.1618
EoL-1 GDSC1; GDSC2; CTRP2 5.2252 6.551 4.4359 2.2291
MOLT-16 GDSC1; GDSC2; CTRP2 5.2271 7.801 3.8152 4.8246
IM-9 GDSC1; GDSC2 5.2299 6.6972 2.8401 0.3743
MOLT-13 GDSC1; GDSC2; CTRP2 5.2794 9.4534 3.0326 8.0095
MV4-11 GDSC1; GDSC2; CTRP2 5.2863 10.5314 2.4998 10.2112
OCI-Ly19 GDSC1; GDSC2; CTRP2 5.3027 8.1217 3.7154 5.1072
Hs 611.T CTRP2 5.3124 10.0799 2.7463 9.142
NALM-6 GDSC1; GDSC2; CTRP2 5.3149 9.8596 2.8583 8.6714
Daudi GDSC1; GDSC2; CTRP2 5.3434 6.983 4.3116 2.549
KG-1 GDSC1; GDSC2 5.3452 9.088 1.8995 4.5343
DG-75 GDSC1; GDSC2 5.4425 7.5136 2.6201 0.9481
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 5.4541 7.9037 3.9509 3.9438
Hs 445 GDSC2 5.4771 7.0827 2.7965 0.3744
SUP-HD1 GDSC1; GDSC2; CTRP2 5.4774 8.0737 3.8737 4.1459
KY821 GDSC1; GDSC2 5.4997 13.6732 -0.1702 15.1243
PL-21 GDSC1; GDSC2 5.5013 7.7718 2.5448 1.1876
MOLT-3 CTRP2 5.5026 9.0313 3.4187 5.9977
MHH-CALL-4 GDSC2; CTRP2 5.5096 7.7168 4.0733 3.2671
ATN-1 GDSC1; GDSC2 5.5615 7.4923 2.6792 0.6638
VL51 GDSC1; GDSC2 5.5689 7.4297 2.7056 0.5784
BL-41 GDSC1; GDSC2; CTRP2 5.5845 7.6277 4.1705 2.7527
CESS GDSC1; GDSC2 5.6153 7.1851 2.8125 0.2836
RS4;11 GDSC1; GDSC2; CTRP2 5.619 9.1111 3.4678 5.5964
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 5.6268 7.3644 4.3382 2.0907
BONNA-12 GDSC2 5.6503 8.341 2.3849 1.7102
L-1236 GDSC1; GDSC2 5.6614 7.6209 2.672 0.6269
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 5.6763 8.3529 3.8938 3.8227
SIG-M5 GDSC2; CTRP2 5.6781 6.7275 4.6539 0.7487
RPMI-8402 GDSC1; GDSC2; CTRP2 5.6937 8.0627 4.0361 3.137
ALL-SIL GDSC1; GDSC2; CTRP2 5.714 8.2005 3.9836 3.3204
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 5.7144 6.9877 4.5705 1.0785
ALL-PO GDSC1; GDSC2 5.7171 8.4636 2.3668 1.7215
BL-70 CTRP2 5.7256 9.9049 3.1559 6.7131
JSC-1 GDSC1; GDSC2 5.7271 8.098 2.5174 1.1068
MLMA GDSC1; GDSC2 5.7354 9.2586 2.0417 3.2189
KO52 CTRP2 5.7507 7.1364 4.512 1.1863
JVM-3 GDSC1; GDSC2; CTRP2 5.7858 10.9324 2.6931 8.5226
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 5.8101 8.8057 3.7686 4.13
RCH-ACV GDSC1; GDSC2; CTRP2 5.8192 7.7364 4.2763 2.0035
JVM-2 GDSC1; GDSC2; CTRP2 5.8205 9.8746 3.2417 6.2024
SET-2 CTRP2 5.8624 7.5211 4.4031 1.4658
BV-173 GDSC1; GDSC2; CTRP2 5.9065 9.5618 3.4577 5.1775
KMS-34 CTRP2 5.9087 10.7902 2.8562 7.6468
SU-DHL-8 GDSC2; CTRP2 5.9113 8.8884 3.7881 3.8235
NCI-H929 GDSC1; GDSC2; CTRP2 5.9127 8.0262 4.2001 2.1811
ST486 GDSC1; CTRP2 5.9233 7.8531 4.2874 1.8319
EB1 CTRP2 5.9464 9.2689 3.6285 4.4192
Pfeiffer CTRP2 5.9494 10.0745 3.2379 6.0121
BALL-1 GDSC1; GDSC2 5.9517 7.61 2.7873 0.2288
RPMI-8866 GDSC1; GDSC2 5.9992 12.2902 0.8242 9.169
NB4 GDSC1; GDSC2; CTRP2 6.0003 8.6108 3.9811 2.9262
CML-T1 GDSC1; GDSC2; CTRP2 6.0375 8.3476 4.1288 2.3008
MOLP-8 GDSC1; GDSC2; CTRP2 6.0379 9.4638 3.5979 4.4089
OCI-AML-5 GDSC1; GDSC2; CTRP2 6.0677 8.4496 4.1003 2.3734
ROS-50 GDSC1; GDSC2 6.0703 8.1761 2.6308 0.5316
M-07e CTRP2 6.0724 9.4109 3.6471 4.1602
HT GDSC1; GDSC2; CTRP2 6.0813 8.21 4.2195 1.9031
JeKo-1 GDSC1; GDSC2; CTRP2 6.0998 9.0227 3.8511 3.3071
KMS-12-BM GDSC1; GDSC2; CTRP2 6.1391 9.739 3.5349 4.5165
JJN-3 GDSC1; GDSC2; CTRP2 6.1504 8.9304 3.9277 2.9389
OCI-Ly3 CTRP2 6.1532 8.2553 4.2418 1.7394
AML-193 CTRP2 6.165 7.8336 4.4358 1.0418
P31/FUJ GDSC1; GDSC2; CTRP2 6.1717 8.7859 4.0089 2.5971
Ci-1 CTRP2 6.2021 6.9742 4.7944 0.0853
EHEB GDSC1; CTRP2 6.2077 10.2743 3.324 5.2689
KMS-21-BM CTRP2 6.2144 13.1691 1.9111 10.9507
PL21 CTRP2; CTRP1 6.219 8.6667 4.1057 2.2412
HEL GDSC1; GDSC2; CTRP2 6.2566 8.9218 3.9987 2.5328
HEL 92.1.7 CTRP2 6.288 7.6619 4.5696 0.5344
HL-60 GDSC1; GDSC2; CTRP2 6.3074 7.869 4.494 0.74
MC116 GDSC1; GDSC2; CTRP2 6.3184 7.2977 4.7228 0.1657
CMK GDSC1; CTRP2 6.3185 7.698 4.5693 0.5164
MEG-01 GDSC1; GDSC2 6.3232 8.3055 2.6805 0.3194
DND-41 GDSC1; GDSC2; CTRP2 6.3237 9.9987 3.5352 4.2572
Raji GDSC1; GDSC2; CTRP2 6.3275 7.7429 4.5554 0.5489
SEM CTRP2 6.332 7.457 4.6692 0.2653
DB GDSC1; GDSC2; CTRP2 6.3338 10.0255 3.5292 4.2673
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 6.3416 7.8632 4.5265 0.6718
SK-MM-2 GDSC1; GDSC2; CTRP2 6.3515 8.0841 4.4261 0.9164
Kasumi-1 GDSC1; GDSC2; CTRP2 6.3841 8.9756 4.0513 2.1882
CA46 GDSC1; GDSC2; CTRP2 6.4274 9.1836 3.9822 2.396
LC4-1 GDSC1; GDSC2 6.4294 8.6194 2.6092 0.4332
Karpas-422 GDSC1; GDSC2; CTRP2 6.4554 9.9976 3.6218 3.7413
Peer CTRP2 6.4806 8.0122 4.5181 0.557
SU-DHL-10 GDSC2; CTRP2 6.4842 7.4592 4.7283 0.113
Mino CTRP2 6.5105 7.4877 4.7279 0.1077
A3/Kawakami GDSC1; GDSC2; CTRP2 6.5172 7.5939 4.6928 0.1577
MOLM-6 CTRP2 6.522 12.4011 2.5129 8.0676
SUP-T11 CTRP2 6.5261 14.0822 1.693 11.2838
EM-2 GDSC1; GDSC2; CTRP2 6.5458 8.3694 4.4038 0.8387
KE-37 GDSC1; GDSC2; CTRP2 6.5478 7.6142 4.6971 0.1428
LP-1 GDSC1; GDSC2; CTRP2 6.5727 8.1754 4.4953 0.5639
KM-H2 GDSC1; GDSC2; CTRP2 6.6147 11.8039 2.8669 6.5152
U266B1 GDSC1; GDSC2; CTRP2 6.6201 9.3514 4.0191 2.054
H9 GDSC1; GDSC2 6.6348 12.7861 0.9825 7.2618
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 6.6883 11.832 2.9152 6.2899
EJM GDSC1; GDSC2; CTRP2 6.6952 8.4825 4.4288 0.669
SU-DHL-1 GDSC2; CTRP2 6.7066 7.9419 4.6403 0.1899
KCL-22 GDSC1; GDSC2; CTRP2 6.7138 9.6603 3.9345 2.2608
Toledo CTRP2 6.7211 15.1595 1.3071 12.4246
KMS-26 CTRP2 6.7317 8.0208 4.6214 0.2143
Ki-JK CTRP2 6.7454 8.4895 4.449 0.5865
DEL GDSC1; GDSC2; CTRP2 6.7459 7.9942 4.6366 0.1848
HPB-ALL CTRP2 6.7492 12.6245 2.5639 7.5247
KMS-27 CTRP2 6.7646 8.4269 4.482 0.4938
P12-Ichikawa GDSC1; CTRP2 6.8325 8.0352 4.6546 0.1365
U-937 CTRP2; CTRP1 6.8381 8.1417 4.633 0.1921
ME1 CTRP2 6.8518 13.5821 2.1719 8.9158
Karpas-620 GDSC1; GDSC2; CTRP2 6.8605 8.6909 4.4212 0.5944
Mono-Mac-1 CTRP2 6.8614 13.8523 2.0475 9.3858
MOTN-1 CTRP2 6.8632 8.6359 4.4439 0.5363
Namalwa GDSC1; GDSC2; CTRP2 6.865 10.5883 3.6027 3.3163
BDCM CTRP2 6.8726 8.5234 4.4914 0.421
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 6.8794 13.5783 2.2045 8.8174
L-428 GDSC1; GDSC2; CTRP2 6.8941 9.7883 3.9788 1.9269
RL GDSC1; GDSC2; CTRP2 6.9033 8.3441 4.5709 0.2493
TF-1 CTRP2 6.909 8.3065 4.5868 0.2201
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 6.9315 14.4801 1.803 10.2897
KMS-20 CTRP2 6.9315 8.5375 4.5106 0.3551
HD-MY-Z CTRP2 6.9757 8.4638 4.5557 0.2533
KE-97 CTRP2 6.9765 13.5432 2.2775 8.3189
OCI-M1 GDSC1; GDSC2; CTRP2 6.9858 8.2867 4.623 0.1458
MOLM-13 GDSC1; GDSC2; CTRP2 6.9964 12.6654 2.7122 6.5897
AMO1 GDSC1; GDSC2; CTRP2 7.0104 8.0773 4.7036 0.0559
PF-382 GDSC1; GDSC2; CTRP2 7.0171 12.1653 2.9632 5.5816
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 7.0322 9.2949 4.2584 0.9297
A4/Fukuda GDSC1; GDSC2; CTRP2 7.0435 8.5714 4.5431 0.2543
Reh GDSC1; GDSC2; CTRP2 7.0568 8.3288 4.6342 0.1175
MOLP-2 CTRP2 7.0822 9.1699 4.3317 0.701
SR GDSC1; GDSC2; CTRP2 7.0853 8.5161 4.579 0.1849
NCO2 CTRP2 7.094 8.9405 4.426 0.4684
RPMI-6666 GDSC1; GDSC2; CTRP2 7.0973 8.6084 4.5505 0.2259
KMS-11 GDSC1; GDSC2; CTRP2 7.1053 9.195 4.3322 0.687
F-36P CTRP2 7.1159 9.5273 4.2036 1.031
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 7.1306 8.7709 4.5185 0.3005
KHM-1B CTRP2 7.1378 8.8826 4.466 0.366
OCI-Ly10 CTRP2 7.1868 13.1891 2.5893 6.809
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 7.215 17.7205 0.4117 14.7981
JURL-MK1 GDSC1; GDSC2; CTRP2 7.2282 8.8566 4.5115 0.2527
MM1.S GDSC1; GDSC2; CTRP2 7.2534 8.9997 4.4692 0.3189
OPM-2 GDSC1; GDSC2; CTRP2 7.2538 8.3983 4.6796 0.0495
Jurkat GDSC1; GDSC2; CTRP2 7.2598 11.7167 3.3239 3.9065
HDLM-2 GDSC1; GDSC2; CTRP2 7.2757 10.0852 4.0511 1.371
L-540 GDSC1; GDSC2; CTRP2 7.3112 10.4222 3.9269 1.7331
SU-DHL-6 GDSC1; GDSC2; CTRP2 7.3882 8.9997 4.5212 0.196
KMM-1 CTRP2 7.4109 10.4923 3.9483 1.5858
P3HR-1 CTRP2 7.4124 8.9256 4.5561 0.145
REC-1 CTRP2 7.4211 9.8103 4.2312 0.7717
L-363 GDSC1; GDSC2; CTRP2 7.4481 8.7344 4.6338 0.0637
K-562 GDSC1; GDSC2; CTRP2 7.4931 8.7072 4.6581 0.0435
KMS-28BM CTRP2 7.5278 10.8022 3.877 1.7178
Mono-Mac-6 GDSC1; GDSC2; CTRP2 7.5485 10.6833 3.9372 1.5157
HuT 78 CTRP2 7.901 10.0826 4.3286 0.3624
Ri-1 CTRP2 8.2479 10.7731 4.2129 0.4575
Ku812 GDSC1; GDSC2; CTRP2 8.3348 17.2375 1.4237 9.6233
Karpas-299 GDSC1; GDSC2; CTRP2 8.7075 15.5482 2.44 5.5228
SUP-T1 GDSC1; GDSC2; CTRP2 9.2858 23.586 -0.974 15.9933
LAMA-84 GDSC1; GDSC2; CTRP2 9.9744 20.8081 0.7941 9.7207
KMS-18 CTRP2 10.8681 26.3086 -1.2142 14.6066
KYO-1 CTRP2 11.7179 24.5428 0.1354 9.8235
⏷ Show the Full List of 220 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 6.2615 9.011 3.9604 2.6735
TE15 CTRP2 7.6258 9.3302 4.4929 0.1822
T.T GDSC1; GDSC2 4.454 6.207 2.6778 1.7351
TE-15 GDSC1; GDSC2 5.7652 7.6845 2.6902 0.5189
TE-5 GDSC1; GDSC2; CTRP2 6.1454 10.2424 3.2959 5.4747
OE19 GDSC1; GDSC2; CTRP2 6.2283 8.9058 3.9885 2.6059
TE-8 GDSC1; GDSC2 6.3988 8.3825 2.6813 0.295
KYSE-270 GDSC1; GDSC2 6.4109 8.8922 2.5031 0.7122
TE-9 GDSC1; GDSC2; CTRP2 6.6057 7.9544 4.5953 0.3094
EC-GI-10 GDSC1; GDSC2; CTRP2 6.6528 9.0064 4.1888 1.4353
KYSE-450 GDSC1; GDSC2; CTRP2 6.7326 8.1779 4.5637 0.3242
TE-6 GDSC1; GDSC2; CTRP2 6.7519 8.5139 3.5173 0.2364
KYSE-30 CTRP2 6.9192 9.5376 4.1008 1.4961
KYSE-150 GDSC1; GDSC2; CTRP2 6.9418 11.1496 3.3909 4.0264
TE-4 GDSC1; GDSC2; CTRP2 6.9645 8.9168 4.3787 0.6455
TE-10 GDSC1; GDSC2; CTRP2 6.9742 9.2684 4.2415 1.0174
OE21 GDSC1; GDSC2; CTRP2 6.977 13.6088 2.2462 8.4404
KYSE-520 GDSC1; GDSC2; CTRP2 7.031 9.7037 4.0879 1.4457
KYSE-180 GDSC1; GDSC2; CTRP2 7.0727 10.9414 3.5657 3.2202
KYSE-140 GDSC1; GDSC2; CTRP2 7.2652 10.5273 3.8577 1.9996
KYSE-70 GDSC1; GDSC2; CTRP2 7.4247 9.3533 4.4073 0.3761
COLO 680N GDSC1; GDSC2; CTRP2 7.43 9.2258 4.4561 0.2863
OE33 GDSC1; GDSC2; CTRP2 7.468 9.5365 4.3566 0.4606
TE-11 GDSC1; GDSC2; CTRP2 7.5211 9.3658 4.4408 0.2853
TE-1 GDSC1; GDSC2; CTRP2 7.7348 9.3339 4.531 0.1188
TE-14 CTRP2 7.7854 9.5508 4.4743 0.1738
KYSE-410 GDSC1; GDSC2; CTRP2 7.8952 9.6882 4.4664 0.1628
KYSE-510 GDSC1; GDSC2; CTRP2 12.4232 22.8733 1.2687 5.8059
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.1765 8.5849 4.5887 0.1507
PL4 GDSC1; GDSC2 5.1137 7.2245 2.5844 1.3881
Capan-1 GDSC1; GDSC2; CTRP2 5.7115 8.4775 3.847 3.8821
Hs 766T GDSC1; GDSC2; CTRP2 5.8384 10.3584 3.0166 7.1022
KP-1N GDSC1; GDSC2 5.8822 7.9685 2.6323 0.6219
MIA PaCa-2 GDSC1; GDSC2; CTRP2 5.9322 7.3142 4.5361 0.9141
PaTu 8988s CTRP2 5.9324 8.3028 4.0825 2.6161
SW1990 GDSC1; GDSC2; CTRP2 6.1187 8.4914 4.1127 2.2637
SNU-213 CTRP2 6.2787 12.0529 2.5081 8.4659
MZ-PC-1 GDSC1; GDSC2 6.4368 8.6893 2.5871 0.4814
PK-45H CTRP2 6.4549 8.9269 4.1144 1.8823
Panc 03.27 GDSC1; GDSC2; CTRP2 6.466 8.6461 4.2448 1.4149
HuP-T4 GDSC1; GDSC2; CTRP2 6.4908 8.3619 4.3796 0.9532
KP-2 GDSC1; GDSC2; CTRP2 6.5013 8.2797 4.4191 0.8248
PaTu 8988t GDSC1; GDSC2; CTRP2 6.5122 7.6359 4.6756 0.1879
SU.86.86 GDSC1; GDSC2; CTRP2 6.5375 8.0939 4.5116 0.5411
Panc 08.13 GDSC1; GDSC2; CTRP2 6.5722 8.9337 4.177 1.5481
KP-3 GDSC1; GDSC2; CTRP2 6.8048 9.946 3.8587 2.439
SUIT-2 GDSC1; GDSC2; CTRP2 6.8238 11.2232 3.2822 4.5915
KP-4 GDSC1; GDSC2; CTRP2 6.8503 10.5173 3.6264 3.2443
Panc 05.04 CTRP2 6.8804 8.9859 4.3121 0.8767
BxPC-3 GDSC1; GDSC2; CTRP2 6.8823 11.0197 3.4142 4.0098
L3.3 CTRP2 7.029 8.193 4.671 0.0824
AsPC-1 GDSC1; GDSC2; CTRP2 7.0454 8.8272 4.4486 0.4396
TCC-Pan2 CTRP2 7.058 8.4634 4.5875 0.1791
YAPC GDSC1; GDSC2; CTRP2 7.0918 8.1874 4.6947 0.0543
PSN1 GDSC1; GDSC2; CTRP2 7.0922 9.0254 4.3927 0.5455
CFPAC-1 GDSC1; GDSC2; CTRP2 7.1171 8.5443 4.581 0.1744
Panc 10.05 GDSC1; GDSC2; CTRP2 7.12 9.379 4.2656 0.8543
QGP-1 GDSC1; GDSC2; CTRP2 7.2604 8.7466 4.5629 0.167
HPAC GDSC1; GDSC2; CTRP2 7.2864 8.7814 4.5603 0.165
PaTu 8902 GDSC1; GDSC2; CTRP2 7.3509 8.5877 4.6496 0.0618
HPAF-II GDSC1; CTRP2 7.3564 9.0735 4.4827 0.2634
SNU-410 CTRP2 7.3713 9.1836 4.4485 0.3178
Panc 02.03 GDSC1; GDSC2; CTRP2 7.3774 8.9316 4.5411 0.171
DAN-G GDSC1; GDSC2; CTRP2 7.3837 8.7683 4.5999 0.1013
HuP-T3 GDSC1; GDSC2; CTRP2 7.5846 9.1707 4.5334 0.1404
Panc 04.03 GDSC1; GDSC2; CTRP2 7.6034 9.157 4.5449 0.1246
Capan-2 GDSC1; CTRP2 7.6161 9.6712 4.3666 0.3863
PK-59 CTRP2 7.8347 9.333 4.5661 0.0753
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.4893 24.7542 -2.1078 20.1152
GAK GDSC1; GDSC2 3.9934 5.4788 2.7385 2.1373
M14 GDSC1 4.1431 5.7009 1.8038 0.6544
COLO 783 GDSC1; GDSC2 4.7874 6.3014 2.8044 0.7788
WM1552C GDSC1; GDSC2 4.7898 6.6361 2.6693 1.355
MZ-MEL-2 GDSC1; GDSC2 4.9691 7.3274 2.4681 2.102
COLO 679 GDSC1; GDSC2 4.9805 6.6651 2.7477 0.837
Hs 938.T GDSC1; GDSC2 5.0165 7.3371 2.4887 1.9409
MMAc-SF GDSC1; GDSC2 5.0269 10.43 1.0688 9.7902
CP66-MEL GDSC1; GDSC2 5.1746 6.2955 2.9616 0.1338
VMRC-MELG GDSC1; GDSC2 5.2144 6.7463 2.816 0.4487
LB2518-MEL GDSC1; GDSC2 5.2425 6.6568 2.8597 0.3189
A-431 GDSC1; GDSC2 5.3311 6.9407 2.7909 0.4588
LB373-MEL-D GDSC1; GDSC2 5.3416 6.6165 2.9109 0.1766
SH-4 GDSC1; GDSC2 5.3753 6.9887 2.7909 0.4365
G-mel GDSC1; GDSC2 5.3766 7.8826 2.4409 1.7482
CHL-1 GDSC1; GDSC2 5.4062 6.9291 2.8246 0.3356
451Lu GDSC1; GDSC2 5.4067 7.3733 2.659 0.8345
A-388 GDSC1; GDSC2 5.4324 8.315 2.2874 2.4008
WM278 GDSC1; GDSC2 5.5693 7.7639 2.5783 1.0043
MZ-MEL-7 GDSC1; GDSC2 5.6775 7.1004 2.8646 0.1688
RVH-421 GDSC1; GDSC2; CTRP2 5.6844 8.093 4.0149 3.237
WM88 CTRP2 5.8841 7.9004 4.2408 2.0593
IST-MEL1 GDSC1; GDSC2 5.9562 7.8423 2.7072 0.3913
DJM-1 GDSC1; GDSC2 5.969 7.8681 2.7029 0.3963
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 6.0476 7.2883 4.6205 0.6015
HMV-II GDSC1; GDSC2 6.0806 7.9497 2.7159 0.3269
CP50-MEL-B GDSC1; GDSC2 6.0879 7.672 2.8145 0.1544
WM35 GDSC1; GDSC2 6.1187 8.0707 2.6873 0.3748
MDA-MB-435S CTRP2 6.1379 8.7351 4.0113 2.63
Hs 940.T GDSC1; GDSC2; CTRP2 6.1489 7.8999 4.3981 1.1852
Hs 934.T CTRP2 6.1973 7.4616 4.608 0.4849
Hs 852.T CTRP2 6.2663 15.5191 0.7873 15.0823
SK-MEL-2 GDSC1; GDSC2; CTRP2 6.2814 7.173 4.7536 0.1253
CJM [Human melanoma] CTRP2 6.3354 10.552 3.2781 5.2689
COLO 829 GDSC1; GDSC2; CTRP2 6.3671 10.3267 3.4076 4.7054
WT2-iPS GDSC1; GDSC2; CTRP2 6.4082 7.6889 4.613 0.3571
COLO 792 GDSC1; GDSC2; CTRP2 6.438 10.5303 3.3579 4.8055
A101D GDSC1; GDSC2; CTRP2 6.4716 7.7789 4.6056 0.3446
Hs 294T CTRP2 6.504 8.1662 4.467 0.6834
IGR-39 CTRP2 6.5627 8.2892 4.4448 0.7079
WM1799 CTRP2 6.5764 10.3167 3.5494 3.8684
Hs 839.T CTRP2 6.6608 7.7469 4.6924 0.1229
UACC-257 GDSC1; GDSC2; CTRP2 6.7186 8.3523 4.4909 0.4956
K029AX CTRP2 6.7242 8.3715 4.4859 0.5049
COLO 800 GDSC1; GDSC2; CTRP2 6.7245 8.4843 4.4415 0.6178
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 6.7287 7.933 4.6661 0.1694
WM266-4 CTRP2 6.7301 7.6416 4.7533 0.0471
A2058 GDSC1; GDSC2; CTRP2 6.7662 7.7438 4.7314 0.0612
HMCB CTRP2 6.771 7.7883 4.7179 0.0732
Hs 936.T CTRP2 6.7884 7.9062 4.6836 0.1082
UACC-62 GDSC1; GDSC2; CTRP2 6.7931 7.9038 4.6861 0.1043
WM793 GDSC1; GDSC2; CTRP2 6.8059 8.3176 4.5414 0.3412
IPC-298 GDSC1; GDSC2; CTRP2 6.8078 8.0038 4.6565 0.1393
LOX-IMVI GDSC1; GDSC2; CTRP2 6.8271 8.6592 4.4187 0.619
WM115 GDSC1; GDSC2; CTRP2 6.8554 8.0795 4.6475 0.1411
SK-MEL-3 GDSC1; GDSC2; CTRP2 6.899 8.1645 4.6338 0.1503
IGR-37 GDSC1; GDSC2; CTRP2 6.939 7.9805 4.7115 0.0575
G-361 GDSC1; GDSC2; CTRP2 7.041 8.415 4.5983 0.1676
SK-MEL-31 GDSC1; GDSC2; CTRP2 7.0799 8.3663 4.6296 0.1188
SK-MEL-30 GDSC1; GDSC2; CTRP2 7.098 8.2816 4.6651 0.0784
HT-144 GDSC1; GDSC2; CTRP2 7.1026 8.9135 4.4399 0.4343
Mel Ho GDSC1; GDSC2; CTRP2 7.105 8.6866 4.5252 0.2664
WM983B CTRP2 7.1131 10.867 3.6229 2.9677
IGR-1 GDSC1; GDSC2; CTRP2 7.1172 9.1162 4.3683 0.5912
Hs 944.T CTRP2 7.1547 9.7547 4.1287 1.2248
Hs 895.T CTRP2 7.2213 8.3767 4.6758 0.0553
COLO 741 CTRP2 7.25 9.0672 4.4429 0.3701
Mel JuSo GDSC1; GDSC2; CTRP2 7.3105 8.7317 4.5864 0.1277
MeWo GDSC1; GDSC2; CTRP2 7.4321 8.7962 4.6075 0.0874
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 7.4576 8.6414 4.6823 0.0416
RPMI-7951 GDSC1; GDSC2; CTRP2 7.5257 8.901 4.6046 0.0784
SK-MEL-24 GDSC1; GDSC2; CTRP2 7.5274 9.671 4.3306 0.491
A-375 GDSC1; GDSC2; CTRP2; CTRP1 7.5463 13.9333 2.4839 6.8053
Hs 688(A).T CTRP2 11.6848 31.0855 -2.9445 17.8591
EquiPSC Line K2 GDSC1; GDSC2 5.7373 8.7741 2.2485 2.2251
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC1; GDSC2 5.4316 8.1013 2.3772 1.9779
KYSE-50 GDSC1; GDSC2 5.6184 7.5348 2.6866 0.6073
KYAE-1 GDSC1; GDSC2 5.8916 7.5585 2.7834 0.2531
ESO-26 GDSC1; GDSC2 6.0129 7.521 2.8394 0.1352
ESO-51 GDSC1; GDSC2 6.0315 7.8544 2.7312 0.3117
HCE-4 GDSC1; GDSC2 6.1584 16.2786 -0.9719 17.1794
OACM5.1 C GDSC1; GDSC2 6.2865 8.5384 2.5835 0.5548
KYSE-220 GDSC1; GDSC2 6.3866 8.1454 2.7584 0.1728
SK-GT-4 GDSC1; GDSC2 6.4283 8.871 2.5179 0.6621
TE-12 GDSC1; GDSC2 6.8128 10.2286 2.1642 1.5673
FLO-1 GDSC1; GDSC2 6.8482 9.0162 2.6243 0.2739
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 7.2923 9.8763 4.1454 1.0804
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-17 GDSC1; GDSC2 3.6716 5.5108 2.5034 4.25
SK-N-BE(2)-M17 GDSC1; GDSC2 3.9604 6.1424 2.4018 4.2099
SJNB-13 GDSC1; GDSC2 3.9762 5.4352 2.7481 2.1136
GOTO GDSC1; GDSC2 4.0414 5.9356 2.555 3.119
IMR-32 CTRP2 4.6309 5.6908 4.3345 3.8917
IMR-5 GDSC1; GDSC2 4.7263 8.0006 2.0237 4.9138
SJNB-14 GDSC1; GDSC2 4.9355 7.8528 2.218 3.4589
SK-N-MC-IXC GDSC1; GDSC2 4.9478 6.0212 2.9746 0.1727
SJNB-10 GDSC1; GDSC2 4.9503 8.8618 1.763 5.9924
NB(TU)1 GDSC1; GDSC2 5.1533 10.0312 1.3433 7.9871
KP-N-YN GDSC1; GDSC2; CTRP2 5.1581 7.7406 3.7898 5.0581
NH-12 GDSC1; GDSC2 5.1613 7.3005 2.5761 1.3755
SJNB-7 GDSC1; GDSC2 5.2615 7.0053 2.7381 0.663
SJNB-6 GDSC1; GDSC2 5.4141 6.9118 2.8338 0.3105
TGW GDSC1; GDSC2 5.4193 6.9508 2.8218 0.3368
KP-N-RT-BM-1 GDSC2 5.5314 7.4557 2.6804 0.6782
SJNB-5 GDSC1; GDSC2 5.5524 7.2898 2.7506 0.4591
NH-6 CTRP2 5.6167 9.5514 3.2482 6.513
NB69 GDSC1; GDSC2 5.6764 7.7415 2.6329 0.7404
LA-N-6 GDSC1; GDSC2 5.6975 7.6692 2.6687 0.6163
Kelly GDSC1; GDSC2; CTRP2 5.8784 9.1069 3.6592 4.396
KP-N-YS GDSC1; GDSC2 6.1487 8.1032 2.687 0.3644
GI-ME-N GDSC1; GDSC2 6.1678 8.5496 2.532 0.7606
SJNB-12 GDSC1; GDSC2 6.2601 8.3081 2.6561 0.3916
SK-N-DZ GDSC1; GDSC2; CTRP2 6.2976 8.1909 4.352 1.2049
CHP-126 GDSC1; GDSC2; CTRP2 6.4628 8.2231 4.4236 0.8392
SK-N-AS GDSC1; GDSC2; CTRP2 6.5075 8.5133 4.3241 1.1157
SK-N-BE(2) CTRP2 6.747 9.0748 4.2088 1.2897
SK-N-FI GDSC1; GDSC2; CTRP2 7.2522 8.7402 4.5621 0.1699
MHH-NB-11 GDSC1; GDSC2; CTRP2 7.3621 8.862 4.5599 0.15
NB1 GDSC1; GDSC2; CTRP2 7.4386 9.0704 4.515 0.1931
SiMa GDSC1; GDSC2; CTRP2 7.4536 9.4197 4.3943 0.3907
SK-N-SH GDSC1; GDSC2; CTRP2 8.0403 15.2992 2.1469 7.371
KP-N-SI9s CTRP2 8.0699 14.5256 2.5251 5.9348
CHP-212 GDSC1; GDSC2; CTRP2 9.4836 20.1803 0.7788 10.3625
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 5.3405 10.0117 2.803 8.8548
SNU-1196 CTRP2 6.894 8.8378 4.3781 0.6868
SNU-869 CTRP2 6.8997 8.9016 4.3553 0.7445
SNU-478 CTRP2 7.0545 9.5645 4.1583 1.2085
SNU-308 CTRP2 7.1629 8.9235 4.461 0.3666
HuH-28 CTRP2 7.2077 8.9004 4.4875 0.3007
HuCC-T1 GDSC1; GDSC2; CTRP2 7.2731 8.9947 4.4788 0.2951
SNU-245 CTRP2 7.5138 10.1589 4.135 0.9699
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BT-483 GDSC1; GDSC2 3.8717 5.3248 2.7333 2.3989
Evsa-T GDSC1; GDSC2 4.1353 5.9801 2.5941 2.7108
UACC-893 GDSC1; GDSC2 4.5954 8.7861 1.5645 7.8713
UACC-812 GDSC2 4.7515 11.1987 0.5021 13.5024
HCC1569 GDSC1; GDSC2 4.7556 7.0965 2.4531 2.4737
MDA-MB-415 GDSC1; GDSC2 4.7759 6.4558 2.7369 1.0677
MDA-MB-157 GDSC1; GDSC2; CTRP2 5.0731 7.4796 3.8506 5.3171
EFM-19 GDSC1; GDSC2 5.1363 7.4882 2.486 1.8105
EFM-192A GDSC1; GDSC2 5.1979 7.3417 2.5768 1.336
HCC1187 GDSC1; GDSC2 5.2743 6.8743 2.7927 0.4841
DU4475 GDSC1; GDSC2; CTRP2 5.3425 7.6674 3.9723 3.9631
MRK-nu-1 GDSC1; GDSC2 5.417 6.7676 2.8858 0.2008
Hs 578T GDSC1; GDSC2; CTRP2 5.4659 8.4606 3.6735 4.9981
COLO 824 GDSC1; GDSC2 5.5189 7.4861 2.6637 0.7409
MFM-223 GDSC1; GDSC2 5.6095 7.1658 2.8171 0.2758
MDA-MB-436 GDSC1; GDSC2 5.6813 7.4114 2.7567 0.3852
HCC1599 GDSC2 5.7007 7.8125 2.6161 0.7793
HCC2157 GDSC1; GDSC2 5.7479 7.1665 2.8669 0.1495
MDA-MB-175-VII GDSC1; GDSC2 5.759 7.2913 2.828 0.2093
HCC70 GDSC1; GDSC2 5.7911 11.1406 1.2286 7.4133
OCUB-M GDSC1; GDSC2 5.9069 7.4885 2.8131 0.1964
AU565 GDSC1; GDSC2; CTRP2 5.917 8.4498 4.0025 2.9537
CAL-51 GDSC1; GDSC2; CTRP2 5.9187 8.0184 4.2076 2.1445
YMB-1-E GDSC2 6.0022 7.976 2.6768 0.445
MDA-MB-330 GDSC1; GDSC2 6.0951 8.0652 2.6803 0.3993
KPL-1 CTRP2 6.1214 7.0135 4.7489 0.1841
MDA-MB-468 GDSC1; GDSC2; CTRP2 6.1627 8.126 4.3056 1.4977
BT-549 GDSC1; GDSC2; CTRP2 6.3743 9.0267 4.0221 2.3074
CAL-148 GDSC2; CTRP2 6.4064 8.1335 4.433 0.8526
HCC202 GDSC1; CTRP2 6.4567 8.724 4.2056 1.5585
MCF-7 GDSC1; GDSC2; CTRP2 6.5209 8.5241 4.3264 1.0974
HMC-1-8 CTRP2 6.5396 7.9893 4.5537 0.4337
BT-20 GDSC1; GDSC2; CTRP2 6.6582 8.1488 4.5434 0.4006
HCC1954 GDSC1; GDSC2; CTRP2 6.713 8.6766 4.3584 0.8557
HCC1937 GDSC1; GDSC2; CTRP2 6.7534 11.7735 2.9754 5.8885
HCC1500 GDSC1; GDSC2; CTRP2 6.7843 8.7009 4.3824 0.7413
ZR-75-30 GDSC1; GDSC2; CTRP2 6.7947 8.7305 4.3753 0.7545
HCC1419 GDSC1; GDSC2; CTRP2 6.8404 8.2478 4.5813 0.2509
MDA-MB-231 GDSC1; GDSC2; CTRP2 6.9262 9.338 4.1889 1.2109
SK-BR-3 CTRP2 6.9966 9.0532 4.3392 0.7301
BT-474 GDSC1; GDSC2; CTRP2 7.014 8.2814 4.6352 0.1243
ZR-75-1 CTRP2 7.039 8.3848 4.6081 0.1543
HCC2218 GDSC1; GDSC2; CTRP2 7.0517 14.1527 2.0352 9.1484
CAL-85-1 GDSC1; GDSC2; CTRP2 7.0591 9.6353 4.131 1.2887
CAL-120 GDSC1; GDSC2; CTRP2 7.0664 8.1741 4.6904 0.0603
HCC38 GDSC1; GDSC2; CTRP2 7.1044 9.1959 4.3315 0.6894
CAMA-1 GDSC1; GDSC2; CTRP2 7.1553 8.9121 4.4622 0.3671
MDA-MB-453 GDSC1; GDSC2; CTRP2 7.1969 8.8572 4.4991 0.2835
JIMT-1 GDSC1; GDSC2; CTRP2 7.2038 10.4372 3.8639 2.0335
T-47D GDSC1; GDSC2; CTRP2 7.2924 9.3103 4.369 0.5075
HCC1806 GDSC1; GDSC2; CTRP2 7.3309 9.0764 4.4717 0.2895
MDA-MB-361 GDSC1; GDSC2; CTRP2 7.381 9.0606 4.4968 0.2341
HCC1143 GDSC1; GDSC2; CTRP2 7.4262 9.6136 4.3098 0.5801
HCC1428 GDSC1; GDSC2; CTRP2 7.4655 12.071 3.2849 3.8209
HDQ-P1 GDSC1; GDSC2; CTRP2 7.533 9.2459 4.4882 0.2091
HCC1395 GDSC1; GDSC2; CTRP2 7.9754 14.4823 2.4869 6.189
Hs 578Bst CTRP2 9.9708 26.5817 -1.9465 17.6465
BT 416 CTRP2 3.2641 12.641 -0.3234 24.999
BT 328 CTRP2 5.6584 7.4362 4.3134 2.0699
BT 482 CTRP2 5.7421 8.2125 3.9974 3.2229
BT 422 CTRP2 5.9072 8.1457 4.1404 2.4216
BT 112 CTRP2 5.9982 8.3622 4.0971 2.4732
BT 228 CTRP2 6.0764 9.7049 3.5081 4.7161
BT 239 CTRP2 6.095 11.0447 2.8684 7.2956
BT 248 CTRP2 6.1082 8.1614 4.2579 1.7298
BT164 CTRP2 6.1357 7.8466 4.4143 1.1418
BT 504 CTRP2 6.1913 11.9402 2.4994 8.641
BT 428 CTRP2 6.2151 8.1085 4.3429 1.3132
BT 145 CTRP2 6.2168 8.1924 4.3067 1.4387
BT 286 CTRP2 6.2779 9.1272 3.9166 2.8216
BT 245 CTRP2 6.3564 9.0637 3.9944 2.4317
BT 179 CTRP2 6.4671 8.8287 4.1651 1.6899
BT 216 CTRP2 6.5113 7.9208 4.568 0.4135
BT 172 CTRP2 6.5629 8.1067 4.5181 0.5102
BT 232 CTRP2 6.596 9.164 4.0888 1.8311
BT 131 CTRP2 6.7091 9.3665 4.0623 1.8139
BT 330 CTRP2 6.7164 11.1406 3.2517 4.8496
BT 440 CTRP2 6.7192 8.0898 4.5911 0.2742
BT 139 CTRP2 6.7524 7.963 4.6502 0.1617
BT 320 CTRP2 6.8036 7.8786 4.6986 0.0882
BT 444 CTRP2 6.8082 8.0005 4.6578 0.1375
BT147 CTRP2 6.8989 8.5061 4.5089 0.3716
BT 159 CTRP2 6.9509 8.29 4.6088 0.174
BT 224 CTRP2 6.9704 8.5305 4.5291 0.3039
BT 340 CTRP2 6.9749 10.3925 3.7563 2.631
BT 498 CTRP2 7.1095 15.0251 1.6528 10.5206
BT 271 CTRP2 7.1147 8.2932 4.667 0.0745
BT 333 CTRP2 7.1416 11.0882 3.5397 3.2407
BT 359 CTRP2 7.2807 8.669 4.5974 0.1204
BT 231 CTRP2 7.3275 9.4688 4.3232 0.5955
BT 187 CTRP2 7.4735 9.7447 4.2798 0.6272
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.0346 8.0317 4.727 0.0374
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PFSK-1 GDSC1 3.2414 6.9783 0.7084 9.6443
M059J GDSC1; GDSC2 3.9034 5.6784 2.586 3.2157
LNZTA3WT4 GDSC1; GDSC2 4.1546 6.0569 2.5704 2.8124
AM-38 GDSC1; GDSC2 4.5148 7.0312 2.342 3.4732
D-247MG GDSC1; GDSC2 4.5413 6.881 2.4266 2.952
D-263MG GDSC1; GDSC2 4.6489 6.2963 2.7409 1.1837
D-542MG GDSC1; GDSC2 5.0112 6.581 2.7939 0.6442
D-423MG GDSC1; GDSC2 5.1018 7.5942 2.4233 2.153
LN-405 GDSC1; GDSC2 5.1175 6.8188 2.748 0.7292
H4 GDSC1; GDSC2 5.2936 11.0994 0.9282 10.0032
SK-MG-1 GDSC1; GDSC2 5.3557 7.0513 2.7598 0.5362
D-502MG GDSC1; GDSC2 5.5225 7.6755 2.5922 0.9893
KINGS-1 GDSC1; GDSC2 5.5237 7.8451 2.5259 1.2432
D-566MG GDSC1; GDSC2 5.5561 7.6927 2.6002 0.9346
MOG-G-CCM GDSC1; GDSC2 5.6041 7.9262 2.5301 1.158
MOG-G-UVW GDSC1; GDSC2 5.6341 7.6621 2.6452 0.7271
Onda 11 GDSC1; GDSC2 5.652 7.5797 2.6835 0.5977
Hs 683 GDSC1; GDSC2; CTRP2 5.8103 7.26 4.491 1.1979
GI-1 GDSC1; GDSC2 6.0544 7.7231 2.7852 0.2059
D283 Med GDSC1; GDSC2; CTRP2 6.0789 7.9104 4.3541 1.4101
KNS-81-FD GDSC1; GDSC2 6.0834 7.6974 2.8043 0.1698
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 6.115 8.7485 2.4342 1.1162
NMC-G1 GDSC1; GDSC2; CTRP2 6.1805 7.9129 4.4097 1.116
GOS-3 CTRP2 6.2169 8.6029 4.1214 2.1155
KNS-81 CTRP2 6.276 7.8827 4.4726 0.8293
Onda 10 GDSC1; GDSC2 6.282 7.9011 2.8046 0.132
U-118MG GDSC1; GDSC2; CTRP2 6.2885 8.7498 4.0972 2.1247
SNU-489 CTRP2 6.2967 7.8503 4.4966 0.7401
KNS-42 GDSC1; GDSC2; CTRP2 6.3196 7.7189 4.5614 0.5373
CCF-STTG1 CTRP2 6.3439 7.8441 4.522 0.6321
D-336MG GDSC1; GDSC2 6.3918 8.4998 2.6376 0.3846
SNU-1105 CTRP2 6.4119 8.3704 4.3353 1.1596
DK-MG GDSC1; GDSC2; CTRP2 6.4306 7.8302 4.5677 0.4561
SNU-738 CTRP2 6.469 8.1202 4.4691 0.7007
D-392MG GDSC1; GDSC2 6.4874 8.6497 2.6203 0.3882
KNS-60 CTRP2 6.4985 7.5099 4.7156 0.1276
SNU-626 CTRP2 6.5023 8.1236 4.4835 0.6382
42-MG-BA GDSC1; GDSC2; CTRP2 6.5241 8.336 4.407 0.8448
SNU-466 CTRP2 6.6389 13.5728 2.025 9.8165
SW1783 GDSC1; GDSC2; CTRP2 6.6401 9.062 4.1579 1.5505
LN-18 GDSC1; GDSC2; CTRP2 6.6613 7.9101 4.6341 0.214
YH-13 GDSC1; GDSC2; CTRP2 6.7004 10.4553 3.563 3.6618
KG-1-C CTRP2 6.7392 7.9943 4.6339 0.191
GMS-10 CTRP2 6.7785 9.6371 3.9815 2.0286
SF295 GDSC1; GDSC2; CTRP2 6.8216 8.9002 4.319 0.8962
A-172 GDSC1; GDSC2; CTRP2 6.9135 13.5885 2.212 8.6674
D-245MG GDSC2 6.9299 9.6002 2.4487 0.6108
CAS-1 GDSC1; GDSC2; CTRP2 6.9425 8.4681 4.5409 0.2912
U-87MG ATCC GDSC1; CTRP2 6.9918 8.0907 4.6926 0.0672
SNU-201 CTRP2 7.0154 17.1171 0.5615 14.6107
Becker GDSC1; GDSC2; CTRP2 7.027 8.7057 4.4868 0.3665
8-MG-BA GDSC1; GDSC2; CTRP2 7.0926 9.3052 4.2826 0.8248
YKG-1 GDSC1; GDSC2; CTRP2 7.1237 8.3751 4.6423 0.0973
Daoy GDSC1; GDSC2; CTRP2 7.1451 8.5494 4.5896 0.1562
SF539 GDSC1; GDSC2; CTRP2 7.1663 9.0658 4.4088 0.4746
TM-31 CTRP2 7.2807 8.6241 4.6128 0.1037
SF268 GDSC1; GDSC2; CTRP2 7.2945 9.037 4.4718 0.3008
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 7.2956 11.2415 3.5727 3.0224
M059K CTRP2 7.3016 11.2016 3.5813 2.9215
U-251MG GDSC1; GDSC2; CTRP2 7.3435 8.6846 4.6143 0.0929
GB-1 GDSC1; GDSC2; CTRP2 7.4478 9.1364 4.495 0.2196
SNB-75 GDSC1; GDSC2; CTRP2 7.4551 9.1723 4.485 0.2329
ONS-76 GDSC1; GDSC2; CTRP2 7.501 9.154 4.5087 0.1878
SF126 GDSC1; GDSC2; CTRP2 7.506 8.8929 4.6005 0.0843
DBTRG-05MG GDSC1; GDSC2; CTRP2 7.5712 9.4054 4.4458 0.2632
SW1088 GDSC1; GDSC2; CTRP2 7.6606 9.4227 4.4733 0.2008
GaMG GDSC1; GDSC2; CTRP2 7.7024 9.3209 4.5239 0.1312
T98G GDSC1; GDSC2; CTRP2 7.7703 9.4576 4.5011 0.145
KALS-1 GDSC1; GDSC2; CTRP2 8.7093 10.6478 4.426 0.0916
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1; GDSC2 4.9715 6.3217 2.8754 0.4072
ETK-1 GDSC1; GDSC2 5.8399 9.027 2.194 2.3599
TGBC24TKB GDSC1; GDSC2 6.1487 7.9483 2.7413 0.2566
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 3.0246 10.0386 0.7215 22.1977
MFE-280 GDSC1; GDSC2 4.8777 7.2712 2.4435 2.3489
JHUEM-7 CTRP2 5.3452 9.998 2.8136 8.802
JHUEM-1 CTRP2 5.479 6.8516 4.4723 1.6841
KLE GDSC1; GDSC2; CTRP2 6.1211 8.2643 4.2187 1.8609
HEC-1-B CTRP2 6.2932 8.5329 4.1981 1.7489
RL95-2 GDSC1; GDSC2; CTRP2 6.4768 8.0017 4.5206 0.5526
AN3-CA GDSC1; GDSC2; CTRP2 6.5612 9.1096 4.0934 1.8494
HEC-251 CTRP2 6.7943 8.1987 4.581 0.267
HEC-108 CTRP2 6.9039 8.0733 4.6675 0.1061
MFE-296 GDSC1; GDSC2; CTRP2 6.9218 8.9881 4.3307 0.798
HEC-6 CTRP2 7.0227 8.513 4.5561 0.2382
EN GDSC1; GDSC2; CTRP2 7.0454 8.631 4.522 0.2913
ESS-1 GDSC1; GDSC2; CTRP2 7.119 8.8922 4.4547 0.3962
HEC-265 CTRP2 7.1429 8.1733 4.7167 0.0354
MFE-319 GDSC1; GDSC2; CTRP2 7.1916 8.4881 4.6277 0.102
HEC-151 CTRP2 7.2788 8.4842 4.6595 0.0617
HEC-1-A CTRP2 7.3085 9.6672 4.2371 0.8191
EFE-184 CTRP2 7.3821 8.9221 4.5462 0.1634
JHUEM-3 CTRP2 7.4736 9.7198 4.2894 0.605
HEC-59 CTRP2 7.4873 8.6089 4.6884 0.0283
HEC-50B CTRP2 7.8838 9.5095 4.5236 0.1051
Ishikawa (Heraklio) 02 ER- CTRP2 6.5825 7.7223 4.6716 0.1738
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC1; GDSC2 4.2106 7.6976 1.8232 7.1794
SW13 GDSC1; GDSC2 4.5053 7.0085 2.3466 3.4637
BB65-RCC GDSC1; GDSC2 4.5926 7.8167 2.0247 5.1631
SW156 GDSC1; GDSC2 5.1569 7.5539 2.4687 1.8673
SN12C GDSC1; GDSC2 5.1574 8.5932 2.0133 4.2192
LB996-RCC GDSC2 5.3234 7.1515 2.7085 0.7211
A-704 GDSC1; GDSC2 5.3787 7.4062 2.634 0.9465
HA7-RCC GDSC1; GDSC2 5.4581 7.6127 2.5882 1.0555
KTCTL-26A GDSC1; GDSC2 5.5496 7.7058 2.5923 0.9681
KTCTL-1M GDSC1; GDSC2 5.7403 7.8177 2.6307 0.7079
KTCTL-195 GDSC1; GDSC2 5.8406 7.3101 2.8507 0.1536
NCC010 GDSC1; GDSC2 5.8548 8.1792 2.5415 0.9269
KTCTL-13 GDSC1; GDSC2 5.8654 7.6815 2.7302 0.3738
NCC021 GDSC1; GDSC2 6.0311 7.5851 2.824 0.1524
KTCTL-21 GDSC1; GDSC2 6.0743 8.1661 2.636 0.5161
CAL-54 GDSC1; GDSC2; CTRP2 6.2451 9.2041 3.8598 3.0828
RXF 393L GDSC1; GDSC2 6.3572 8.7713 2.5262 0.6748
KMRC-2 CTRP2 6.4697 9.0271 4.078 1.998
TUHR10TKB CTRP2 6.4897 7.5326 4.7043 0.147
LB2241-RCC GDSC1; GDSC2 6.5138 8.4257 2.7078 0.2201
KMRC-1 GDSC1; GDSC2; CTRP2 6.6677 8.6677 4.34 0.9421
A-498 GDSC1; GDSC2; CTRP2 6.7129 8.0212 4.6139 0.2337
VMRC-RCW GDSC1; GDSC2; CTRP2 6.8699 8.5029 4.4981 0.4073
TUHR14TKB CTRP2 6.9316 15.5224 1.2829 21.3917
TK-10 GDSC1; GDSC2 6.9481 9.0075 2.6625 0.1944
LB1047-RCC GDSC1; GDSC2 6.9505 9.2802 2.5698 0.3417
769-P GDSC1; GDSC2; CTRP2 7.0177 8.468 4.5705 0.2159
RCC10RGB GDSC1; GDSC2; CTRP2 7.0467 8.344 4.6253 0.1303
TUHR4TKB CTRP2 7.0843 8.6393 4.5343 0.2569
BFTC-909 GDSC1; GDSC2; CTRP2 7.1485 8.7553 4.5172 0.2668
OS-RC-2 GDSC1; GDSC2; CTRP2 7.2089 8.8384 4.5106 0.2599
UO-31 GDSC1; GDSC2; CTRP2 7.2595 9.2767 4.3678 0.5247
KMRC-20 GDSC1; GDSC2; CTRP2 7.2965 8.9439 4.5064 0.2418
Caki-2 CTRP2 7.3184 8.9745 4.5037 0.2399
VMRC-RCZ GDSC1; GDSC2; CTRP2 7.411 8.8488 4.5821 0.1156
786-O GDSC1; GDSC2; CTRP2 7.4416 9.162 4.4835 0.2387
KMRC-3 CTRP2 7.6908 9.707 4.383 0.3326
SNU-1272 CTRP2 7.6968 9.3379 4.5161 0.1407
Caki-1 GDSC1; GDSC2; CTRP2 7.7143 10.0216 4.276 0.5298
ACHN GDSC1; GDSC2; CTRP2 7.736 9.4154 4.5034 0.1483
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC1; GDSC2; CTRP2 4.2134 15.257 -0.77 24.1559
GP5d GDSC1; GDSC2 4.2986 7.2143 2.1172 5.2083
SW1116 GDSC1; GDSC2 4.8003 10.9703 0.6489 12.6052
HCC2998 GDSC1; GDSC2 5.1869 6.9145 2.7411 0.7037
SW837 GDSC1; GDSC2 5.2618 7.0145 2.7347 0.6742
SW948 GDSC1; GDSC2; CTRP2 5.3194 8.7893 3.3959 6.4157
SNU-283 GDSC2 5.3215 6.884 2.808 0.4165
SNU-C2B GDSC1; GDSC2 5.3523 8.3004 2.2518 2.6779
SNU-175 GDSC2; CTRP2 5.5327 7.6852 4.1055 3.098
SK-CO-1 GDSC1; GDSC2; CTRP2 5.6393 7.8928 4.0804 3.0377
CL-40 CTRP1 5.6503 8.023 4.0361 7.0261
COLO 320HSR GDSC1; GDSC2 5.6942 7.6907 2.6593 0.6465
CL-34 CTRP1 5.8091 10.3819 2.9938 15.0205
HT115 GDSC1; GDSC2; CTRP2; CTRP1 5.8095 7.3097 4.4804 1.3066
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 5.8454 8.5472 3.9187 3.4669
C2BBe1 GDSC1; GDSC2; CTRP2 5.8751 8.8595 3.7769 3.9218
SNU-503 CTRP2 6.2157 8.3455 4.2376 1.6878
LS180 GDSC1; GDSC2; CTRP2 6.2685 8.6451 4.133 2.0142
SNU-1040 CTRP1 6.2696 7.8508 4.4961 1.7533
CCK-81 GDSC1; GDSC2; CTRP2 6.3328 8.9368 4.0383 2.294
HCC-56 CTRP2 6.3477 7.4502 4.6783 0.2401
CaR-1 GDSC1; GDSC2 6.3831 8.1763 2.7467 0.1903
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 6.4079 7.9664 4.5162 0.6569
SW626 GDSC1; GDSC2 6.4338 8.3628 2.7008 0.2508
GP2d CTRP2 6.485 10.74 3.2892 5.0138
SNU-C4 CTRP2 6.4993 7.6415 4.6685 0.2047
CL-11 GDSC1; GDSC2; CTRP2 6.5139 9.0392 4.0979 1.8808
HCT 8 CTRP2; CTRP1 6.5445 8.4109 4.3992 0.9068
DLD-1 CTRP2 6.5928 7.9952 4.5744 0.3602
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 6.6559 8.8094 4.2879 1.1679
CW-2 GDSC1; GDSC2; CTRP2 6.6666 9.2511 4.0896 1.7598
DiFi GDSC1; GDSC2 6.6731 9.0243 2.5571 0.4587
OUMS-23 CTRP2 6.6997 7.7164 4.7172 0.085
LS411N GDSC1; GDSC2; CTRP2 6.7069 8.0387 4.6051 0.252
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 6.7102 7.977 4.643 0.2128
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 6.714 8.4829 4.4509 0.6453
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 6.7515 7.983 4.6569 0.1778
LS123 GDSC1; GDSC2; CTRP2; CTRP1 6.7613 8.4861 4.4711 0.5655
COLO205 GDSC1; GDSC2; CTRP2 6.8158 8.3837 4.5206 0.3815
COLO 320 CTRP2 6.8188 10.3573 3.6806 3.0777
SNU-C5 GDSC1; GDSC2; CTRP2 6.9158 9.7781 3.9951 1.8512
SNU-407 GDSC1; GDSC2; CTRP2 6.9674 9.0872 4.3121 0.821
SNU-C1 GDSC1; GDSC2; CTRP2 6.9923 8.745 4.4575 0.4433
NCI-H508 GDSC1; GDSC2; CTRP2; CTRP1 6.9986 8.4964 4.5669 0.2562
LS513 GDSC1; GDSC2; CTRP2 7.0336 8.5384 4.5512 0.2433
SW480 CTRP1 7.0566 11.0918 3.5 7.4237
SNU-1033 CTRP2 7.0854 9.3007 4.2811 0.8332
SW620 GDSC1; GDSC2; CTRP2; CTRP1 7.1459 8.6137 4.5813 0.1913
SW1417 GDSC1; GDSC2; CTRP2 7.1547 8.9583 4.4446 0.4029
LS1034 GDSC1; GDSC2; CTRP2 7.1792 8.5174 4.6132 0.1201
HCT 15 GDSC1; GDSC2; CTRP2 7.2327 8.745 4.5532 0.1869
SW48 GDSC1; GDSC2; CTRP2 7.2807 9.3283 4.3571 0.5392
SNU-61 GDSC1; GDSC2; CTRP2 7.3871 9.1024 4.4841 0.2525
NCI-H716 GDSC1; GDSC2; CTRP2 7.4055 9.2641 4.4325 0.3355
KM12 GDSC1; GDSC2; CTRP2 7.4786 8.7877 4.6264 0.0662
RKO GDSC1; GDSC2; CTRP2; CTRP1 7.5064 9.3031 4.4719 0.2662
NCI-H747 GDSC1; GDSC2; CTRP2 7.529 9.4067 4.429 0.3027
LoVo GDSC1; GDSC2; CTRP2; CTRP1 7.544 10.0192 4.2176 0.7834
SW1463 GDSC1; GDSC2; CTRP2 7.5638 19.2418 -0.0798 15.8516
T84 GDSC1; GDSC2; CTRP2 7.5658 9.6214 4.3649 0.4073
COLO201 CTRP2 11.8348 23.0992 0.8508 7.5713
SNU-C2A CTRP2 12.2148 29.1356 -1.6787 14.2454
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 5.7114 7.6667 2.6753 0.5892
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Huh-7 GDSC1; GDSC2 4.7751 6.3489 2.7799 0.8879
HLE GDSC1; GDSC2 4.8788 8.0357 2.1015 4.1975
JHH-7 GDSC1; GDSC2 5.2243 6.822 2.7918 0.5147
Hep-G2/C3A GDSC1; GDSC2 5.2951 6.4659 2.9461 0.1302
Hep-G2 CTRP2 5.9821 7.7153 4.3858 1.3974
SNU-761 CTRP2 6.1319 8.1599 3.3986 0.7957
SNU-398 GDSC1; GDSC2; CTRP2 6.1398 8.5031 4.1203 2.2097
SNU-387 GDSC1; GDSC2; CTRP2 6.2726 8.865 4.0347 2.3772
JHH-6 GDSC1; GDSC2; CTRP2 6.3528 7.0883 4.809 0.0443
SNU-182 CTRP2 6.4158 12.3745 2.4499 8.4835
HuH-1 GDSC1; GDSC2; CTRP2 6.78 8.2979 4.5381 0.3588
SK-HEP-1 GDSC1; GDSC2; CTRP2 6.8046 7.9515 4.6737 0.1174
PLC/PRF/5 CTRP2 6.8664 8.3526 4.553 0.2949
SNU-423 GDSC1; GDSC2; CTRP2 6.9014 8.859 4.3731 0.6958
SNU-878 CTRP2 6.9538 8.6371 4.4823 0.4056
SNU-449 GDSC1; GDSC2; CTRP2 6.9825 9.1634 4.2884 0.8775
JHH-1 GDSC1; GDSC2; CTRP2 7.0217 8.2443 4.6508 0.1046
JHH-5 CTRP2 7.1037 8.9931 4.4101 0.4998
JHH-4 GDSC1; GDSC2; CTRP2 7.1611 8.5545 4.5936 0.1475
SNU-475 CTRP2 7.2085 8.39 4.6669 0.0635
HLF CTRP2 7.2557 8.6399 4.5984 0.1236
JHH-2 GDSC1; GDSC2; CTRP2 7.3537 9.2585 4.4138 0.389
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 7.4931 9.2193 4.4826 0.2269
HuH-6 CTRP2 7.6629 10.3607 4.1226 0.9163
Li-7 CTRP2 8.3092 10.1754 4.4466 0.1199
SNU-886 CTRP2 9.8099 31.1077 -4.2606 22.926
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 222 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H209 GDSC1; GDSC2 3.3361 6.0921 1.9486 8.6494
NCI-H2803 GDSC1; GDSC2 3.3898 8.6064 0.7361 15.8303
NCI-H64 GDSC1; GDSC2 3.7492 4.9202 2.8447 1.9819
NCI-H1304 GDSC1 4.1143 5.8903 1.7188 1.0442
NCI-H847 GDSC1; GDSC2 4.1412 5.6664 2.7416 1.866
NCI-H187 GDSC1 4.1643 5.309 1.9533 0.1869
NCI-H1876 GDSC1; GDSC2 4.1746 6.2839 2.4769 3.3194
NCI-H2347 GDSC1; GDSC2 4.249 6.1284 2.5954 2.5013
NCI-H345 GDSC1; GDSC2 4.2549 5.1393 3.0236 0.3794
NCI-H2804 GDSC1; GDSC2 4.3088 6.7563 2.341 3.8584
Lu-139 GDSC1; GDSC2 4.4646 6.9263 2.3596 3.4616
NCI-H2373 GDSC1; GDSC2 4.4715 6.3601 2.6202 2.0105
COR-L279 GDSC1; GDSC2 4.6037 6.1212 2.7912 1.0065
NCI-H1963 GDSC1; GDSC2 4.6331 6.6024 2.6025 1.8731
SBC-1 GDSC1; GDSC2 4.7073 7.0208 2.4596 2.5108
COR-L23 GDSC1; GDSC2 4.7235 6.4571 2.7109 1.238
NCI-H1993 GDSC1; GDSC2 4.7526 6.7421 2.6056 1.7016
NCI-H2369 GDSC1; GDSC2 4.7962 6.1064 2.884 0.4847
NCI-H720 GDSC1; GDSC2 4.8083 6.5247 2.7243 1.0897
Lu-165 GDSC1; GDSC2 4.8155 6.1199 2.8869 0.4629
NCI-H2461 GDSC1; GDSC2 4.8457 7.1288 2.4882 2.1649
Lu-135 GDSC1; GDSC2 4.8692 7.2453 2.4502 2.3266
NCI-H835 GDSC1; GDSC2 4.8998 7.148 2.5087 1.9904
Lu-99A GDSC1; GDSC2 4.9332 8.4894 1.9256 5.0949
NCI-H290 GDSC1; GDSC2 4.945 6.7384 2.7022 1.0508
NCI-H1648 GDSC1; GDSC2 5.0263 7.143 2.5753 1.5218
NCI-H1105 GDSC1; GDSC2; CTRP2 5.0885 7.0367 4.0848 3.9492
NCI-H510A GDSC1; GDSC2 5.1008 9.3437 1.6329 6.449
RERF-LC-KJ GDSC1; GDSC2 5.1223 6.821 2.7493 0.7212
NCI-H1436 GDSC1; GDSC2 5.1473 7.025 2.6805 0.9575
SBC-3 GDSC1; GDSC2 5.1541 6.9245 2.723 0.792
NCI-H322M GDSC1; GDSC2 5.1968 11.7413 0.5538 12.2114
LK-2 GDSC1; GDSC2 5.2083 7.1902 2.6427 1.0543
COR-L311 GDSC2 5.225 7.6293 2.4713 1.7768
DV-90 CTRP2 5.2464 8.9402 3.2622 7.109
NCI-H2722 GDSC1; GDSC2 5.2695 7.0263 2.7335 0.6731
LC-1/sq GDSC1; GDSC2 5.2759 8.6844 2.0408 3.8816
NCI-H1836 GDSC1; GDSC2 5.2852 6.7857 2.8296 0.3761
HCC33 GDSC2 5.3042 6.701 2.8674 0.2761
NCI-H2066 GDSC1; GDSC2 5.3235 7.0484 2.7477 0.5925
NCI-H82 GDSC1; GDSC2 5.3332 6.8304 2.832 0.3483
COR-L321 GDSC1; GDSC2 5.3834 7.0623 2.767 0.4997
EMC-BAC-2 GDSC1; GDSC2 5.3846 7.4907 2.6034 1.0578
NCI-H250 GDSC2 5.4324 7.144 2.7565 0.5039
NCI-H146 GDSC1; GDSC2; CTRP2 5.4516 7.3882 4.1921 2.869
IST-SL2 GDSC1; GDSC2 5.4623 7.5568 2.612 0.9627
NCI-H2444 GDSC1; GDSC2; CTRP2 5.4885 6.4729 3.7672 0.16
NCI-H1770 GDSC1; GDSC2 5.4947 6.927 2.8586 0.2293
NCI-H596 GDSC1; GDSC2; CTRP1 5.5001 7.0879 4.3844 2.6788
NCI-H2141 GDSC1; GDSC2; CTRP2 5.5138 7.8049 4.0331 3.4263
COR-L303 GDSC2 5.5208 6.8913 2.8804 0.1817
NCI-H3255 GDSC1; GDSC2 5.5451 7.1572 2.7958 0.3474
LB647-SCLC GDSC1; GDSC2 5.5696 7.2195 2.7829 0.3685
NCI-H2081 GDSC1; GDSC2; CTRP2 5.5716 8.44 3.7634 4.4482
NCI-H1573 GDSC1; GDSC2; CTRP2 5.5733 7.7828 4.087 3.1109
NCI-H2795 GDSC1; GDSC2 5.6026 8.2609 2.3948 1.7156
COLO 668 GDSC1; GDSC2; CTRP2 5.6077 7.9516 4.0293 3.2947
NCI-H211 GDSC1; GDSC2; CTRP2 5.6266 8.4078 3.8197 4.127
NCI-H1184 CTRP2 5.6496 9.1014 3.4955 5.4311
NCI-H810 GDSC1; GDSC2; CTRP2 5.6506 7.2814 4.3818 1.8093
Ms-1 GDSC1; GDSC2 5.7012 7.4403 2.754 0.3836
EMC-BAC-1 GDSC1; GDSC2 5.7328 8.6481 2.2986 2.0037
LC-2/ad GDSC1; GDSC2 5.7514 7.548 2.7345 0.4101
A-427 GDSC1; GDSC2 5.7584 10.9658 1.2892 7.146
NCI-H1734 GDSC1; GDSC2; CTRP2 5.7602 8.0306 4.0976 2.7919
NCI-H2591 GDSC1; GDSC2 5.7848 9.9137 1.7817 4.4767
NCI-H1688 GDSC1; GDSC2 5.8 7.6761 2.7069 0.458
COR-L32 GDSC2 5.8054 7.8542 2.6437 0.6305
NCI-H2171 GDSC2; CTRP2 5.8226 7.7355 4.2789 1.9891
NCI-H2087 GDSC1; GDSC2; CTRP2 5.8234 8.9132 3.7145 4.2535
CPC-N GDSC1; GDSC2 5.8253 7.7201 2.7008 0.4622
NCI-H2227 GDSC1; GDSC2 5.8416 7.5274 2.7758 0.2833
NCI-H1651 GDSC1; GDSC2 5.8458 8.6799 2.3398 1.7101
NCI-H1092 GDSC1; GDSC2; CTRP2 5.8592 8.6773 3.854 3.6325
UMC-11 GDSC1; GDSC2 5.8602 7.5073 2.7897 0.2504
NCI-H1048 GDSC1; GDSC2 5.8631 7.529 2.7832 0.2619
NCI-H2135 GDSC1; GDSC2 5.8725 7.2321 2.888 0.0999
Lu-134-A GDSC1; GDSC2 5.8746 8.3623 2.4793 1.1333
NCI-H2869 GDSC1; GDSC2 5.8792 8.0987 2.5824 0.7757
DMS 273 GDSC1; GDSC2; CTRP2 5.8855 8.395 4.0076 2.9771
DMS 79 GDSC1; GDSC2; CTRP2 5.9481 8.5806 3.9609 3.0772
IST-SL1 GDSC1; GDSC2 5.9494 7.7346 2.7429 0.3151
NCI-H1869 GDSC1; CTRP2 5.9513 8.132 4.1751 2.2294
EPLC-272H GDSC1; GDSC2; CTRP2 5.9811 8.3655 4.0845 2.5445
NCI-H524 GDSC1; GDSC2; CTRP2 6.0176 8.852 3.8778 3.3127
PaCa-3 GDSC1; GDSC2 6.0203 7.9753 2.684 0.4202
NCI-H1341 GDSC1; GDSC2; CTRP2 6.0398 8.3605 4.1243 2.3155
NCI-H1781 GDSC1; GDSC2; CTRP1 6.0656 8.1021 4.2719 2.3032
NCI-H1975 GDSC1; GDSC2; CTRP2 6.0879 8.5105 4.0846 2.4088
SW1573 GDSC1; GDSC2 6.1094 8.6179 2.482 0.9558
ABC-1 GDSC1; GDSC2 6.1095 8.5507 2.5075 0.872
NCI-H2810 GDSC1; GDSC2 6.1183 8.1949 2.6426 0.4797
NCI-H2106 CTRP2 6.1228 7.9707 4.3522 1.3718
NCI-H2405 GDSC1; GDSC2; CTRP2 6.1238 8.7785 3.982 2.7614
NCI-H513 GDSC1; GDSC2 6.1348 8.003 2.7172 0.3065
NCI-H3122 GDSC1; GDSC2 6.1388 9.3375 2.2113 1.9687
RERF-LC-Sq1 GDSC1; GDSC2 6.1529 8.9863 2.3583 1.3652
NCI-H1437 GDSC1; GDSC2 6.163 7.7735 2.8063 0.1509
MOR/CPR CTRP2 6.2036 7.1845 4.7186 0.2137
SK-MES-1 GDSC1; GDSC2; CTRP2 6.2194 8.4083 4.2114 1.7793
NCI-H889 CTRP2 6.2285 8.1947 4.3123 1.4075
NCI-H2731 GDSC1; GDSC2 6.236 8.1632 2.6983 0.3118
SHP-77 GDSC1; GDSC2; CTRP2 6.2371 8.3625 4.2423 1.648
COR-L95 GDSC1; GDSC2; CTRP2 6.3152 7.9917 4.4466 0.8804
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 6.3423 8.7108 4.1592 1.9045
NCI-H2085 GDSC1; GDSC2; CTRP2 6.3499 13.9318 1.6362 11.7924
NCI-H748 GDSC2 6.3604 8.2231 2.7226 0.233
NCI-H446 GDSC1; GDSC2; CTRP2 6.3785 8.8382 4.1102 1.9778
T3M-10 CTRP2; CTRP1 6.3918 8.4922 4.2845 1.4094
Sq-1 CTRP2 6.4008 8.697 4.1863 1.681
SW1271 GDSC1; GDSC2; CTRP2 6.4033 9.0392 4.0337 2.2318
NCI-H2126 CTRP2 6.4085 7.6404 4.6317 0.3142
NCI-H2595 GDSC1; GDSC2 6.4167 9.1406 2.4126 0.9846
Lu-99 CTRP2 6.4619 8.7705 4.1879 1.6148
NCI-H196 GDSC1; GDSC2; CTRP2 6.4941 11.3595 2.9981 6.1645
NCI-H740 GDSC2 6.4972 9.0723 2.4712 0.7578
IA-LM GDSC1; GDSC2; CTRP2 6.5032 7.9821 4.5404 0.4859
NCI-H1944 GDSC1; GDSC2; CTRP2 6.5094 8.9447 4.1374 1.7456
NCI-H1563 GDSC1; GDSC2; CTRP2 6.5497 9.7331 3.8042 2.9238
HCC1195 CTRP2 6.5565 8.8785 4.1925 1.5094
SBC-5 GDSC1; GDSC2; CTRP2 6.5568 7.4289 4.7649 0.0579
LUDLU-1 CTRP2 6.562 8.2756 4.45 0.6939
NCI-H358 GDSC1; GDSC2; CTRP2 6.5641 9.7431 3.8083 2.8912
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 6.5855 8.2222 4.4961 0.6007
NCI-H727 GDSC1; GDSC2; CTRP2 6.5895 9.1225 4.1036 1.7856
HCC2108 CTRP2 6.5901 9.1991 4.0699 1.9035
BEN GDSC1; GDSC2; CTRP2 6.5937 7.7174 4.6777 0.1608
RERF-LC-Ad1 CTRP2 6.5951 7.4023 4.787 0.0357
NCI-H1793 GDSC1; GDSC2; CTRP2 6.6096 15.8582 0.8801 14.1643
Lu-65 GDSC1; GDSC2; CTRP2 6.6153 10.3571 3.5553 3.7968
LK2 CTRP2 6.6206 7.9793 4.5921 0.3101
NCI-H226 GDSC1; GDSC2; CTRP2 6.6775 7.9396 4.6298 0.2166
DMS 53 GDSC1; GDSC2; CTRP2 6.6808 8.8407 4.2742 1.135
NCI-H1666 GDSC1; GDSC2; CTRP2 6.6954 8.8648 4.2714 1.1323
NCI-H69 GDSC1; GDSC2; CTRP2 6.6963 11.6523 2.9951 5.8896
HCC366 GDSC1; GDSC2; CTRP2 6.6977 8.908 4.2543 1.1843
NCI-H1155 GDSC1; GDSC2; CTRP2 6.7024 8.5862 4.3903 0.7713
COR-L51 CTRP2 6.7249 8.8569 4.2896 1.0532
ChaGo-K-1 GDSC1; GDSC2; CTRP2 6.7389 8.993 4.2394 1.1988
RERF-LC-Ad2 CTRP2 6.7551 9.6971 3.9416 2.1928
NCI-H1792 GDSC1; GDSC2; CTRP2 6.7769 8.9748 4.2662 1.0857
NCI-H841 GDSC1; GDSC2; CTRP2 6.8009 8.7058 4.3881 0.7154
NCI-H2172 GDSC1; GDSC2; CTRP2 6.8071 8.6425 4.4162 0.6367
SK-LU-1 GDSC1; CTRP2; CTRP1 6.8211 8.541 4.4762 0.5214
NCI-H1650 GDSC1; GDSC2; CTRP2 6.8212 9.3848 4.1149 1.5335
NCI-H1915 GDSC1; GDSC2; CTRP2 6.83 8.981 4.2899 0.9758
NCI-H2029 GDSC1; GDSC2; CTRP2 6.8401 8.2181 4.592 0.232
VMRC-LCD GDSC1; GDSC2; CTRP2 6.8529 8.6838 4.4206 0.6
NCI-H1694 GDSC1; GDSC2; CTRP2 6.8534 8.2726 4.5774 0.2538
NCI-H1581 GDSC1; GDSC2; CTRP2 6.8553 8.2979 4.5688 0.2688
HCC4006 CTRP2 6.8725 9.6216 4.0398 1.7391
NCI-H647 GDSC1; GDSC2; CTRP2 6.8769 9.8382 3.9474 2.052
NCI-H838 GDSC1; GDSC2; CTRP2 6.8844 8.2494 4.5979 0.2087
NCI-H2291 GDSC1; GDSC2; CTRP2 6.8851 9.1954 4.228 1.1217
NCI-H1623 GDSC1; GDSC2; CTRP2 6.8907 9.0279 4.2999 0.9047
NCI-H1435 GDSC1; GDSC2; CTRP2 6.8966 9.3009 4.1896 1.2314
NCI-H2818 GDSC1; GDSC2 6.8998 14.1797 0.5057 9.1686
HCC44 GDSC1; GDSC2; CTRP2 6.9226 11.7503 3.0978 5.1812
NCI-H2228 GDSC1; GDSC2; CTRP2 6.9586 13.8168 2.1329 8.9085
EBC-1 GDSC1; GDSC2; CTRP2 6.9645 8.871 4.3967 0.6001
Calu-1 CTRP2 6.9737 10.3569 3.7716 2.5773
NCI-H1299 GDSC1; GDSC2; CTRP2 7.0017 9.4006 4.2003 1.1202
LC-1/sq-SF CTRP2 7.0056 8.2578 4.6403 0.1197
HCC1438 CTRP2 7.0196 8.7759 4.4573 0.4319
NCI-H526 GDSC1; GDSC2; CTRP2 7.0252 10.2086 3.8664 2.191
COR-L88 GDSC1; GDSC2; CTRP2 7.0535 8.7655 4.4753 0.3797
NCI-H322 CTRP2 7.0647 8.5378 4.5634 0.2142
NCI-H2030 GDSC1; GDSC2; CTRP2 7.0663 9.1961 4.3141 0.756
NCI-H1395 CTRP2 7.0714 10.9091 3.5796 3.1706
NCI-H1568 GDSC1; GDSC2; CTRP2 7.1046 18.2587 0.0657 16.1192
HOP-62 GDSC1; GDSC2; CTRP2 7.1229 8.9044 4.4517 0.4009
NCI-H1703 GDSC1; GDSC2; CTRP2 7.1277 14.8881 1.7321 10.1938
LCLC-103H GDSC1; GDSC2; CTRP2 7.1458 8.1229 4.7342 0.0262
HCC1588 CTRP2 7.1505 12.869 2.7174 6.3608
HCC1171 CTRP2 7.1566 9.2344 4.3396 0.6412
NCI-H650 GDSC1; GDSC2; CTRP2 7.1617 9.8098 4.1093 1.2783
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 7.1933 9.3741 4.3011 0.7183
HCC95 CTRP2 7.1935 8.5989 4.59 0.1455
NCI-H1373 CTRP2 7.196 9.1042 4.4067 0.4664
NCI-H2170 GDSC1; GDSC2; CTRP2 7.2002 8.7244 4.5482 0.2021
Calu-3 GDSC1; GDSC2; CTRP2 7.2107 9.276 4.3471 0.5957
NCI-H1693 GDSC1; GDSC2; CTRP2 7.2141 9.0456 4.4363 0.3967
NCI-H2286 CTRP2 7.2317 19.5134 -0.458 17.5555
COLO 699 CTRP2 7.2394 18.9411 -0.1703 16.654
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 7.2534 8.1952 4.7605 0.017
NCI-H2009 GDSC1; GDSC2; CTRP2 7.2566 13.4338 2.5191 6.9864
HCC78 GDSC1; GDSC2; CTRP2 7.2711 9.0101 4.4724 0.3072
Calu-6 GDSC1; GDSC2; CTRP2 7.2849 8.8681 4.5291 0.2095
COR-L105 GDSC1; GDSC2; CTRP2 7.293 10.3769 3.9368 1.7162
NCI-H292 GDSC1; GDSC2; CTRP2 7.2955 8.7715 4.5671 0.1542
NCI-H2196 GDSC2; CTRP2 7.3714 8.8207 4.5776 0.1272
NCI-H2110 GDSC1; GDSC2; CTRP2 7.3966 9.6387 4.2874 0.6465
NCI-H522 GDSC2; CTRP2 7.4056 9.2411 4.441 0.3202
CAL-12T GDSC1; GDSC2; CTRP2 7.43 9.3606 4.4067 0.3752
NCI-H1339 CTRP2 7.4316 8.8814 4.5782 0.1164
PC-14 GDSC1; GDSC2; CTRP2 7.4319 9.003 4.5362 0.1661
HCC2935 CTRP2 7.4433 9.457 4.3763 0.4301
DMS 114 GDSC1; GDSC2; CTRP2 7.4753 9.2451 4.4666 0.2562
NCI-H2342 GDSC1; GDSC2; CTRP2 7.48 12.2929 3.1926 4.1446
NCI-H520 GDSC1; GDSC2; CTRP2 7.4802 9.3971 4.4134 0.3457
LCLC-97TM1 GDSC1; GDSC2; CTRP2 7.5047 9.5168 4.3789 0.4021
NCI-H23 GDSC1; GDSC2; CTRP2 7.5187 10.873 3.8423 1.8349
NCI-H1838 GDSC1; GDSC2; CTRP2 7.6234 9.5971 4.3967 0.3297
NCI-H1355 GDSC1; GDSC2; CTRP2 7.6847 9.4895 4.4587 0.2156
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 7.6938 13.5246 2.7685 5.5439
EKVX GDSC1; GDSC2; CTRP2 7.7805 9.8737 4.3575 0.3493
RERF-LC-A1 CTRP2 7.8157 9.1944 4.6057 0.0502
RERF-LC-MS GDSC1; GDSC2; CTRP2 7.8571 9.5028 4.5165 0.1154
DMS 454 CTRP2 7.8636 9.8226 4.4077 0.2463
NCI-H661 GDSC1; GDSC2; CTRP2 7.8674 9.7033 4.4511 0.1866
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 7.8775 10.813 4.0542 1.0178
HOP-92 GDSC1; GDSC2; CTRP2 7.9777 9.8317 4.4466 0.1712
NCI-H1385 CTRP2 8.0729 25.209 -2.6387 21.9963
A-549 GDSC1; GDSC2; CTRP2 8.0738 14.2506 2.654 5.4564
HCC827 GDSC1; GDSC2; CTRP2 8.442 17.0538 1.5802 8.9237
HCC2279 CTRP2 8.533 20.4415 0.0236 14.0753
LXF 289 GDSC1; GDSC2; CTRP2 8.5702 17.231 1.5791 8.7634
NCI-H2023 GDSC1; GDSC2; CTRP2 9.5854 18.6505 1.5499 7.6535
LOU-NH91 GDSC1; GDSC2; CTRP2 10.2312 22.3466 0.2393 11.1759
HCC1833 CTRP2 10.8419 26.6544 -1.395 15.1194
KNS-62 GDSC1; GDSC2; CTRP2 11.1075 19.2268 2.1412 4.2795
Hs 888.Lu CTRP2 6.295 11.0693 2.9998 6.4513
⏷ Show the Full List of 222 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 5.7026 7.5019 2.7323 0.437
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 5.9324 12.9073 1.8263 11.7663
H-STS CTRP2 6.1954 7.0036 4.7815 0.1049
P-STS CTRP2 6.5644 8.4679 4.372 0.9208
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 6.9375 8.4013 4.5635 0.2516
Aska-SS CTRP2 7.7733 19.3029 0.0416 15.1402
STS-0421 GDSC1; GDSC2 4.231 6.6602 2.336 4.0409
SW684 GDSC1; GDSC2 4.4351 5.6373 2.908 0.6746
VA-ES-BJ GDSC1; GDSC2 4.8238 9.5275 1.3639 8.5495
Hs 633.T GDSC1; GDSC2 5.162 6.6361 2.8356 0.4202
TE 441.T GDSC2; CTRP2 5.1729 6.1264 4.6064 1.6075
MFH-ino GDSC1; GDSC2 5.1794 7.9194 2.3244 2.5435
TE 617.T CTRP2 5.4781 8.1088 3.8569 4.2145
EW-8 GDSC1; GDSC2 5.5588 6.9242 2.8828 0.1681
G-401 GDSC1; GDSC2; CTRP2 5.5912 8.1035 3.9432 3.6743
SW872 GDSC1; GDSC2 5.6286 7.098 2.8479 0.2099
BT-12 CTRP2 5.8749 6.5756 4.8118 0.1516
Rh30 GDSC1; GDSC2 6.1211 7.6648 2.8284 0.13
SW982 GDSC1; GDSC2; CTRP2 6.376 11.8642 2.6704 7.6592
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 6.4786 8.4459 4.351 1.1103
Tm87-16 CTRP2 6.5053 9.9507 3.6756 3.4691
MES-SA GDSC1; GDSC2; CTRP2 6.51 7.7656 4.6267 0.2822
A-204 GDSC1; GDSC2; CTRP2 6.6945 10.4948 3.5409 3.7535
KYM-1 GDSC1; GDSC2; CTRP2 6.8348 10.659 3.5517 3.5433
RKN GDSC1; GDSC2; CTRP2 6.87 7.8705 4.7246 0.0546
GCT GDSC1; GDSC2; CTRP2 7.022 12.5645 2.7773 6.3004
BT-16 CTRP2 7.0815 8.3964 4.6197 0.1304
Hs 729.T CTRP2 7.1678 9.1109 4.3923 0.511
Rh18 GDSC1; CTRP2 7.2431 8.821 4.53 0.2189
G-402 GDSC1; GDSC2; CTRP2 7.3174 12.3604 3.0625 4.8215
SK-LMS-1 GDSC1; GDSC2; CTRP2 7.3337 9.476 4.3231 0.5928
Rh41 GDSC1; GDSC2; CTRP2 7.3338 10.0416 4.0976 1.1904
TTC-709 CTRP2 9.747 23.5852 -0.6604 14.4818
SK-UT-1 GDSC1; GDSC2; CTRP2 9.9713 19.2534 1.5047 7.3825
RD GDSC1; GDSC2; CTRP2 12.7683 23.8006 1.052 6.1478
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.5765 20.6516 -0.7626 17.9088
OVCAR-3 GDSC1; GDSC2 5.3291 7.1822 2.6992 0.7491
ES-2 GDSC1; GDSC2 5.3509 6.6906 2.8885 0.2156
JHOS-4 GDSC1; GDSC2 5.5322 7.1462 2.7949 0.355
A2780 GDSC1; GDSC2; CTRP2 5.5446 8.7121 3.6089 5.1343
COV434 CTRP2 5.5742 7.875 4.0426 3.2918
OVKATE GDSC1; GDSC2 5.8731 7.4564 2.8121 0.2067
COV644 CTRP2; CTRP1 5.8868 9.3637 3.5513 4.9012
Caov-3 GDSC2; CTRP2; CTRP1 6.0241 13.8734 1.4279 13.2158
ONCO-DG-1 CTRP2 6.0561 9.1038 3.7834 3.6364
DOV13 GDSC1; GDSC2; CTRP2 6.1396 7.9488 4.3714 1.2871
JHOM-1 CTRP2 6.298 9.1941 3.898 2.8683
Caov-4 GDSC1; GDSC2 6.3038 8.2891 2.6791 0.3283
SK-OV-3 GDSC1; GDSC2; CTRP2 6.3803 8.6369 4.2014 1.648
OVK18 GDSC1; GDSC2; CTRP2 6.4427 10.8052 3.2296 5.3108
OAW42 GDSC1; CTRP2 6.4667 7.4003 4.7424 0.0979
COV362 CTRP2 6.4802 11.2527 3.04 6.0163
JHOS-2 GDSC1; GDSC2; CTRP2 6.5604 8.5773 4.3241 1.0727
OV56 GDSC1; GDSC2; CTRP2 6.689 7.5588 4.7669 0.0411
OVCAR-4 GDSC1; GDSC2; CTRP2 6.7161 13.0556 2.332 8.4915
OVCAR-5 GDSC1; GDSC2; CTRP2 6.7164 9.2345 4.124 1.5959
SNU-119 CTRP2 6.8432 9.4979 4.0778 1.6376
SNU-8 CTRP2 6.8859 7.9422 4.706 0.0687
EFO-21 GDSC1; GDSC2; CTRP2 6.9853 8.724 4.4625 0.4352
OAW28 GDSC1; GDSC2; CTRP2 6.9902 10.1991 3.8511 2.2784
TOV-112D GDSC1; GDSC2; CTRP2 7.0563 10.1838 3.8944 2.065
OVISE GDSC1; GDSC2; CTRP2 7.0787 8.3572 4.6323 0.1158
Kuramochi GDSC1; GDSC2; CTRP2 7.1236 10.7654 3.6746 2.7705
EFO-27 GDSC1; GDSC2; CTRP2 7.1257 8.6139 4.5594 0.2041
FU-OV-1 GDSC1; GDSC2; CTRP2 7.1381 8.898 4.4604 0.3772
OV7 CTRP2; CTRP1 7.1937 9.9572 4.0769 1.4079
TOV-21G GDSC1; GDSC2; CTRP2 7.2034 8.4313 4.6512 0.0773
ES2 CTRP2 7.2734 8.4296 4.6759 0.0503
OVSAHO CTRP2 7.3573 11.0532 3.6782 2.5256
HEY A8 CTRP2 7.391 9.6102 4.2961 0.6286
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 7.394 8.8884 4.5766 0.1438
RMG-I GDSC1; GDSC2; CTRP2 7.4046 9.9294 4.1765 0.9236
RMUG-S CTRP1 7.5403 14.5678 2.1795 15.0024
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 7.5456 11.4564 3.6176 2.6173
OVTOKO GDSC1; GDSC2; CTRP2 7.6236 12.8207 3.0375 4.5565
JHOC-5 CTRP2 7.6777 8.945 4.6416 0.0398
MCAS CTRP2 7.7954 9.4692 4.5062 0.1353
IGROV-1 GDSC1; GDSC2; CTRP2 7.8658 9.8387 4.4028 0.2529
OVCAR-8 GDSC1; GDSC2; CTRP2 8.1601 9.724 4.5466 0.0592
SNU-840 CTRP2; CTRP1 12.766 22.6694 1.5445 4.7946
OC 314 GDSC1; GDSC2; CTRP2 14.2367 26.1271 0.8198 5.6472
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2 6.1763 9.3809 3.7314 3.6784
NCI-H2452 GDSC1; GDSC2; CTRP2 6.2863 10.0191 3.5004 4.4474
ACC-MESO-1 CTRP2 6.7776 8.0742 4.6199 0.2032
JL-1 CTRP2 7.2074 8.6577 4.5745 0.1629
IST-Mes1 GDSC1; GDSC2; CTRP2 7.6758 15.1601 1.9757 8.4889
MPP 89 GDSC1; GDSC2; CTRP2 7.7157 9.2192 4.5632 0.091
NCI-H2052 GDSC1; GDSC2; CTRP2 7.8494 15.7883 1.7918 8.9378
NCI-H28 GDSC1; GDSC2; CTRP2 7.8614 9.5048 4.5174 0.114
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 GDSC2; CTRP2 5.745 12.8556 1.7062 12.5691
PC-3 GDSC1; GDSC2 6.1751 8.3388 2.6126 0.5306
VCaP GDSC1; GDSC2; CTRP2 6.5382 8.0009 4.5486 0.447
LNCaP clone FGC GDSC1; GDSC2; CTRP2 6.6941 10.1453 3.7025 3.1388
PaCa-3 CTRP2 6.7919 8.2755 4.5515 0.326
22Rv1 GDSC1; GDSC2; CTRP2 6.8206 10.0984 3.7993 2.6381
DU145 GDSC1; GDSC2; CTRP2 7.0278 9.134 4.3212 0.7596
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 6.5565 9.3645 3.9765 2.275
A-253 GDSC1; GDSC2; CTRP2 7.7771 9.402 4.5227 0.1209
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 4.4705 6.2308 2.6764 1.7192
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC1; GDSC2 4.588 6.6378 2.5624 2.144
TMK-1 GDSC1; GDSC2 5.0221 6.9736 2.6431 1.2259
TGBC11TKB GDSC1; GDSC2 5.1588 8.5755 2.0221 4.1688
RF-48 GDSC1; GDSC2 5.258 7.5325 2.5276 1.4887
SCH GDSC1; GDSC2 5.349 6.7991 2.8494 0.3001
Fu97 GDSC1; GDSC2; CTRP2 5.3894 7.1666 4.2553 2.7076
GSU CTRP2 5.6517 6.497 4.74 0.4806
Hs 746.T GDSC1; GDSC2; CTRP2 5.8318 7.9595 4.1793 2.3679
SNU-620 CTRP2 5.9599 14.0489 1.2805 13.8177
IM95 GDSC1; GDSC2; CTRP2 6.0096 8.2456 4.1588 2.2197
GCIY GDSC1; GDSC2 6.0472 7.616 2.8192 0.1559
MKN28 GDSC1; GDSC2 6.2151 8.6556 2.5117 0.7948
SNU-668 CTRP2 6.3412 7.8202 4.5305 0.6098
SNU-16 GDSC1; GDSC2; CTRP2 6.3499 7.8879 4.507 0.6715
HGC-27 GDSC1; GDSC2; CTRP2 6.3631 12.3246 2.4363 8.6208
MKN45 GDSC1; GDSC2; CTRP2 6.4397 7.5598 4.6748 0.2132
SNU-601 CTRP2 6.4774 11.9996 2.6766 7.4797
SK-GT-2 GDSC1; GDSC2 6.4923 9.5832 2.2749 1.4084
GSS CTRP2 6.5075 10.0046 3.6518 3.5586
ECC12 GDSC2; CTRP2 6.5742 7.918 4.5959 0.321
NUGC-4 GDSC1; GDSC2; CTRP2 6.5912 9.6333 3.8749 2.6109
RERF-GC-1B GDSC1; GDSC2 6.5933 8.881 2.578 0.4418
SNU-1 GDSC1; GDSC2; CTRP2 6.6299 10.5139 3.4911 4.0271
KATO III GDSC1; GDSC2; CTRP2 6.7038 8.9149 4.2545 1.179
HuG1-N CTRP2 6.7252 10.1046 3.7399 2.9625
23132/87 GDSC1; GDSC2; CTRP2 6.7413 8.9806 4.2459 1.1765
MKN7 GDSC1; GDSC2; CTRP2 6.759 10.1794 3.726 2.9761
OCUM-1 GDSC1; GDSC2; CTRP2 6.7638 10.0341 3.7951 2.715
NCI-N87 GDSC1; CTRP2 6.9676 9.5362 4.1264 1.3742
ECC10 GDSC1; GDSC2; CTRP2 6.9907 10.3747 3.7733 2.5535
SNU-5 GDSC1; GDSC2; CTRP2 7.0541 12.9141 2.6321 6.8236
MKN74 CTRP2 7.0787 9.7278 4.102 1.3635
SH-10-TC CTRP2 7.0976 8.4265 4.6151 0.133
SNU-216 CTRP2 7.2389 9.0042 4.4618 0.3376
LMSU CTRP2 7.2527 8.8372 4.5279 0.2196
AGS GDSC1; GDSC2; CTRP2 7.3602 8.5554 4.6635 0.0509
NUGC-3 GDSC1; GDSC2; CTRP2 7.4068 13.255 2.7013 6.0874
MKN1 GDSC1; GDSC2; CTRP2 7.4703 9.0044 4.5497 0.1419
SNU-719 CTRP2 8.1663 17.7808 1.0526 11.1652
KE-39 CTRP2 8.1833 11.8435 3.7678 1.5695
SNU-685 CTRP2 6.3103 8.5087 4.2188 1.6568
SNU-1077 CTRP2 7.028 8.7228 4.4808 0.3784
SNG-M GDSC1; GDSC2; CTRP2 7.4183 9.023 4.5242 0.185
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1; GDSC2 5.1032 6.5398 2.8477 0.4167
KMH-2 GDSC1; GDSC2 5.1905 7.1345 2.6567 1.014
ASH-3 GDSC1; GDSC2 5.2521 6.5365 2.9061 0.212
K5 GDSC1; GDSC2 5.4448 7.1946 2.7427 0.5374
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 5.8295 8.8133 3.7674 4.0286
WRO GDSC1; GDSC2 5.8725 7.1749 2.9071 0.0799
HTC-C3 GDSC1; GDSC2 5.8736 7.7674 2.7025 0.4367
SW579 CTRP2 6.1158 8.8814 3.9284 2.981
8305C GDSC1; GDSC2; CTRP2 6.7467 8.7854 4.33 0.9157
TT GDSC1; GDSC2; CTRP2 6.7549 8.6927 4.3719 0.7892
FTC-133 GDSC1; GDSC2; CTRP2 6.7688 8.2917 4.5358 0.3685
CAL-62 GDSC1; GDSC2; CTRP2 6.8372 8.0191 4.662 0.1257
BHT-101 GDSC1; GDSC2; CTRP2 6.8414 8.3004 4.5623 0.286
B-CPAP GDSC1; GDSC2; CTRP2 6.9863 8.451 4.5645 0.2348
CGTH-W-1 GDSC1; GDSC2; CTRP2 7.1134 8.809 4.4835 0.3406
TT2609-C02 GDSC1; GDSC2; CTRP2 7.4835 9.1748 4.4948 0.2113
8505C GDSC1; GDSC2; CTRP2 7.5415 9.3861 4.4413 0.2786
FTC-238 CTRP2 7.5648 13.7267 2.581 6.3448
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-15A GDSC1; GDSC2 3.438 9.1651 0.4965 17.0134
BICR 10 GDSC1 3.9988 5.8886 1.6667 1.4303
KOSC-2 GDSC1; GDSC2 4.3965 7.3635 2.1113 5.0424
PCI-38 GDSC1 4.8648 14.0542 -1.5839 18.6808
HO-1-u-1 GDSC1; GDSC2 4.9162 7.5149 2.3577 2.7405
SAT [Human HNSCC] GDSC1; GDSC2 4.9479 12.1243 0.1912 14.6362
JHU-022 GDSC1; GDSC2 5.2533 7.5939 2.5001 1.6153
PCI-30 GDSC1; GDSC2 5.2534 10.4718 1.2001 8.5886
LB771-HNC GDSC1; GDSC2 5.2604 9.1491 1.8215 5.1026
KON GDSC1; GDSC2 5.3985 7.0192 2.7889 0.4306
PCI-06A GDSC1; GDSC2 5.4011 10.653 1.2105 8.2395
BB49-HNC GDSC1 5.4416 7.5623 1.6341 0.4669
JHU-011 GDSC1; GDSC2 5.4614 12.2361 0.4972 11.9334
UPCI-SCC-090 GDSC1; GDSC2 5.5979 7.443 2.7124 0.5427
HO-1-N-1 GDSC1; GDSC2 5.6694 7.3603 2.7705 0.3572
PCI-04B GDSC1; GDSC2 5.6937 8.9233 2.1635 2.6759
BICR 78 GDSC1; GDSC2 5.7514 9.4576 1.964 3.5873
BB30-HNC GDSC1; GDSC2 5.8006 8.0018 2.5862 0.8129
JHU-029 GDSC1; GDSC2 5.8059 8.7014 2.3121 1.8682
NCI-H3118 GDSC1; GDSC2 5.8323 8.7229 2.3159 1.8252
BICR 31 GDSC2; CTRP2 5.8572 10.0903 3.1626 6.469
SCC-15 GDSC1; GDSC2 5.9529 8.1666 2.5873 0.7163
SAS GDSC1; GDSC2 5.9628 11.2253 1.294 6.7659
BICR 22 GDSC1; GDSC2; CTRP2 6.0416 9.7614 3.4564 4.9773
OSC-20 GDSC1; GDSC2 6.0614 8.2366 2.6051 0.6054
BHY GDSC1; GDSC2; CTRP2 6.2146 8.044 4.3709 1.2168
DOK GDSC1; GDSC2 6.2315 8.5705 2.55 0.6728
SKN-3 GDSC1; GDSC2 6.3124 10.8148 1.6764 4.2595
SCC-9 GDSC1; GDSC2; CTRP2 6.408 9.0675 4.0236 2.2641
Ca9-22 GDSC1; GDSC2 6.4416 8.0227 2.8185 0.0939
OSC-19 GDSC1; GDSC2 6.4749 7.97 2.847 0.0661
BICR 56 CTRP2 6.4908 8.2533 4.4249 0.8151
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 6.5015 8.1574 4.4694 0.6784
BICR 6 CTRP2 6.5041 8.3727 4.3818 0.9363
BICR 18 CTRP2 6.5603 8.2833 4.4461 0.706
PE/CA-PJ34 (clone C12) CTRP2 6.6355 8.5888 4.3569 0.9147
CAL-27 GDSC1; GDSC2; CTRP2 6.8319 8.3911 4.5245 0.3662
SNU-1076 CTRP2 6.8442 9.2659 4.1778 1.3101
HSC-4 GDSC1; GDSC2; CTRP2 6.8535 8.4212 4.5221 0.3623
YD-10B CTRP2 6.9306 8.4426 4.5456 0.2866
PE/CA-PJ49 CTRP2 6.9843 8.3706 4.5926 0.1899
SNU-46 CTRP2 7.0826 13.3786 2.4291 7.576
SNU-899 CTRP2 7.0888 9.0491 4.382 0.5725
HSC-3 GDSC1; GDSC2; CTRP2 7.1204 8.3575 4.6471 0.0928
SCC-4 GDSC1; GDSC2; CTRP2 7.1598 11.2249 3.4884 3.409
SNU-1214 CTRP2 7.2811 10.4306 3.9077 1.8207
FaDu GDSC1; GDSC2; CTRP2 7.2983 8.8815 4.5294 0.2057
SNU-1066 CTRP2 7.2996 9.097 4.4518 0.3355
HSC-2 GDSC1; GDSC2; CTRP2 7.4946 8.8501 4.611 0.0767
PE/CA-PJ41 (clone D2) CTRP2 7.5276 9.2668 4.4787 0.2241
BICR 16 CTRP2 7.5346 9.0708 4.5499 0.1304
SNU-1041 CTRP2 7.546 9.2168 4.5033 0.1854
CAL-33 GDSC1; GDSC2; CTRP2 7.5909 9.3919 4.4581 0.2391
Detroit 562 GDSC1; GDSC2; CTRP2 7.6037 9.391 4.4633 0.2282
SCC-25 GDSC1; GDSC2; CTRP2 7.7298 9.5952 4.4381 0.2343
YD-8 CTRP2 7.9095 19.755 -0.0814 15.3239
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 GDSC1; GDSC2; CTRP2 5.1131 6.507 2.8637 0.2754
SW780 GDSC1; GDSC2 5.3307 7.2549 2.6718 0.8447
JMSU-1 CTRP2 6.2609 8.084 4.3787 1.1479
5637 GDSC1; GDSC2; CTRP2 6.325 10.9045 3.1008 5.9985
639V GDSC1; GDSC2; CTRP2 6.3862 7.3395 4.7339 0.1283
647V GDSC1; GDSC2; CTRP2 6.4479 8.8677 4.1369 1.809
RT-112 GDSC1; GDSC2; CTRP2 6.4664 8.1757 4.445 0.7725
KU-19-19 GDSC1; GDSC2; CTRP2 6.8058 7.8519 4.7085 0.0775
BC-3C CTRP2 6.8625 9.2145 4.2087 1.1982
U-BLC1 CTRP2 6.8761 9.7204 3.9987 1.8755
SCaBER CTRP2 6.9017 8.3616 4.5638 0.2625
CAL-29 GDSC1; GDSC2; CTRP2 6.9729 8.5712 4.5149 0.3305
BFTC-905 GDSC1; GDSC2; CTRP2 7.0984 8.5738 4.5634 0.2052
UM-UC-3 GDSC1; GDSC2; CTRP2 7.1068 12.1432 3.0313 5.2019
253J-BV CTRP2 7.1698 8.639 4.5671 0.1817
TCCSUP GDSC1; GDSC2; CTRP2 7.1827 8.6023 4.5849 0.1544
RT-4 GDSC1; GDSC2; CTRP2 7.1874 11.963 3.1661 4.5854
SW1710 GDSC1; GDSC2; CTRP2 7.3293 8.9064 4.5322 0.1942
UM-UC-1 CTRP2 7.3517 12.1093 3.1994 4.2657
KMBC-2 CTRP2 7.4524 9.9792 4.1785 0.8901
J82 GDSC1; GDSC2; CTRP2 7.4546 13.2939 2.7136 5.9796
T24 GDSC1; GDSC2; CTRP2 7.5026 10.0447 4.1753 0.8699
VM-CUB-1 CTRP2 7.621 9.5145 4.4256 0.2818
HT-1376 GDSC1; GDSC2; CTRP2 7.8225 9.6099 4.4673 0.1753
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SiHa GDSC1; GDSC2 4.4179 5.69 2.8786 0.8151
OVCA420 GDSC1; GDSC2 4.5013 6.3244 2.6523 1.8003
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 5.0288 6.6501 2.7748 0.6986
DoTc2 4510 GDSC1; GDSC2 5.1416 6.7155 2.7977 0.5455
CAL-39 GDSC1; GDSC2 5.1758 7.0843 2.6699 0.9747
ME-180 GDSC1; GDSC2 5.1929 7.533 2.4956 1.7015
NEC8 GDSC1; GDSC2 5.2474 9.2316 1.7758 5.3786
JEG-3 GDSC1; GDSC2 5.2493 7.2173 2.6505 0.9887
KGN GDSC1; GDSC2 5.257 7.6947 2.4599 1.7933
NT2-D1 GDSC1; GDSC2 5.4225 7.0983 2.7694 0.4724
PA-1 GDSC1; GDSC2 5.4766 7.1211 2.7824 0.4106
C-4-I GDSC1; GDSC2 5.4954 7.1663 2.7733 0.4258
NCC-IT GDSC2 5.535 7.1926 2.7792 0.3925
OVCA433 GDSC1; GDSC2 5.5896 7.292 2.7644 0.4057
DSH1 GDSC1; GDSC2 5.5934 7.5288 2.6786 0.6463
PWR-1E GDSC1; GDSC2 5.5938 7.5444 2.6729 0.664
SW962 GDSC1; GDSC2 5.5995 7.5544 2.6715 0.665
JAR GDSC1; GDSC2 5.6734 7.1397 2.8496 0.1947
TC-YIK GDSC1; GDSC2 5.6758 7.4401 2.7442 0.4185
BPH-1 GDSC1; GDSC2 5.6798 8.3658 2.3889 1.6638
Ca Ski GDSC1; GDSC2 5.7 8.2569 2.4423 1.4224
HEC-1 GDSC1; GDSC2 5.7093 7.5055 2.7335 0.4308
HEY GDSC1; GDSC2 5.7179 7.7297 2.6544 0.6477
HT-3 GDSC1; GDSC2 5.7422 7.4725 2.7581 0.3573
LB831-BLC GDSC1; GDSC2 5.7611 7.5749 2.7285 0.4206
SKG-IIIa GDSC1; GDSC2 5.8111 7.316 2.8382 0.1791
SW756 GDSC1; GDSC2 5.8355 7.3756 2.8264 0.1922
SKN GDSC1; GDSC2 5.8525 8.7307 2.3224 1.7775
OVMIU GDSC1; GDSC2 5.8564 8.131 2.5606 0.8612
SW954 GDSC1; GDSC2 5.8756 7.4564 2.813 0.2046
PEO1 GDSC1; GDSC2 5.9067 8.086 2.5985 0.709
MS751 GDSC1; GDSC2 6.0195 7.5582 2.8291 0.1476
ACC-OV7 GDSC1; GDSC2 6.1375 13.8795 0.1649 12.204
SiSo GDSC1; GDSC2 6.1498 7.7588 2.8067 0.153
C-33 A GDSC1; GDSC2 6.2502 8.2186 2.6841 0.3358
JHOS-3 GDSC1; GDSC2 6.3233 7.9055 2.8172 0.1111
UWB1.289 GDSC1; GDSC2 6.7273 9.0385 2.5724 0.4064
HeLa GDSC1; GDSC2; CTRP2 6.8359 7.7125 4.7656 0.0296
OV17R GDSC1; GDSC2 6.8536 8.8389 2.6866 0.1801
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7417).
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.