Details of the Drug

General Information of Drug (ID: DM4JG0B)

Drug Name
DA-3607
Synonyms Ad-stTRAIL; TRAIL adenoviral gene therapy (cancer), Dong-A
Indication
Disease Entry ICD 11 Status REF
Brain cancer 2A00 Phase 1 [1]
Cross-matching ID
TTD ID
D0V3ZX

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TNF related apoptosis inducing ligand (TNFSF10) TTA5MS9 TNF10_HUMAN Binder [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Brain cancer
ICD Disease Classification 2A00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
TNF related apoptosis inducing ligand (TNFSF10) DTT TNFSF10 4.40E-01 -0.16 -0.18
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026657)
2 Cancer gene therapy using a novel secretable trimeric TRAIL. Gene Ther. 2006 Feb;13(4):330-8.