Details of the Drug

General Information of Drug (ID: DM4XPYJ)

Drug Name

Avicin D

Synonyms

Avicin D (cancer)

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]
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Structure

3D MOL is unavailable

2D MOL

Chemical Identifiers

Formula: C98H155NO46
Canonical SMILES: CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3CCC4(C(C3(C)C)CCC5(C4CC=C6C5(CC(C7(C6CC(C(C7)OC(=O)C(=CCCC(C)(C=C)OC8C(C(C(C(O8)C)OC(=O)C(=CCCC(C)(C=C)O)CO)O)O)CO)(C)C)C(=O)OC9C(C(C(C(O9)CO)O)O)OC1C(C(C(C(O1)C)OC1C(C(C(O1)CO)O)O)OC1C(C(C(C(O1)CO)O)O)O)O)O)C)C)C)NC(=O)C)O)O)OC1C(C(C(CO1)O)O)O)O)O
InChI: 1S/C98H155NO46/c1-16-93(11,127)26-18-20-45(34-101)81(125)139-75-41(4)132-87(73(122)69(75)118)145-94(12,17-2)27-19-21-44(33-100)80(124)137-57-32-98(90(126)144-89-79(68(117)62(111)50(36-103)135-89)143-86-74(123)77(141-85-72(121)66(115)61(110)49(35-102)133-85)76(42(5)131-86)140-84-71(120)63(112)51(37-104)134-84)47(30-91(57,7)8)46-22-23-54-95(13)28-25-56(92(9,10)53(95)24-29-96(54,14)97(46,15)31-55(98)107)138-82-58(99-43(6)105)65(114)64(113)52(136-82)39-129-88-78(67(116)59(108)40(3)130-88)142-83-70(119)60(109)48(106)38-128-83/h16-17,20-22,40-42,47-79,82-89,100-104,106-123,127H,1-2,18-19,23-39H2,3-15H3,(H,99,105)/b44-21+,45-20+/t40-,41-,42+,47+,48-,49-,50-,51+,52-,53+,54-,55-,56+,57+,58-,59+,60+,61-,62-,63+,64-,65-,66+,67+,68+,69-,70-,71-,72-,73-,74-,75-,76+,77+,78-,79-,82+,83+,84+,85+,86+,87+,88-,89+,93+,94+,95+,96-,97-,98-/m1/s1
InChIKey: HKEDBKXRDHFCFB-LUAQNYIXSA-N

Cross-matching ID

PubChem CID: 44566777
CAS Number: 197787-20-5
UNII: 69451KN1RO
DrugBank ID: DB17240
TTD ID: D0R5VO

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MEC1	CTRP2	0.6804	4.015	0.5944	36.0088
JM1	CTRP2	-0.2334	1.2637	-0.2335	41.8239
M-07e	CTRP2	-2.2859	-0.7426	-2.2859	55.4973
Daudi	CTRP2	-2.0031	-1.048	-2.0031	53.6135
Mino	CTRP2	-1.8341	-1.2382	-1.8341	52.4878
JeKo-1	CTRP2	-1.736	-0.8316	-1.736	51.8343
ST486	CTRP2	-1.6782	-0.9455	-1.6782	51.4488
CMK	CTRP2	-1.5745	-1.086	-1.5745	50.7583
U266B1	CTRP2	-1.5536	-0.0241	-1.5536	50.619
RL	CTRP2	-1.5183	-0.9557	-1.5183	50.3839
SET-2	CTRP2	-1.4568	-0.7936	-1.4568	49.9743
OPM-2	CTRP2	-1.4212	-0.8126	-1.4212	49.7367
EB1	CTRP2	-1.4037	-0.3666	-1.4037	49.6203
CA46	CTRP2	-1.3909	-0.099	-1.391	49.5353
TF-1	CTRP2	-1.3752	0.6771	-1.3758	49.4305
MOLT-3	CTRP2	-1.3661	-0.9636	-1.3661	49.3698
GA-10	CTRP2	-1.3586	-0.6149	-1.3586	49.3198
Pfeiffer	CTRP2	-1.3554	-0.6818	-1.3554	49.2987
Karpas-422	CTRP2	-1.3089	0.1657	-1.3089	48.9886
HH [Human lymphoma]	CTRP2	-0.7274	2.5989	-0.7616	45.1856
SEM	CTRP2	-0.7115	3.5706	-0.8296	45.2215
A3/Kawakami	CTRP2	-0.5698	2.6042	-0.5991	44.1342
DND-41	CTRP2	-0.5236	1.2213	-0.524	43.7582
F-36P	CTRP2	-0.5229	2.8053	-0.562	43.8451
SUP-HD1	CTRP2	-0.498	1.701	-0.5009	43.5949
OCI-Ly19	CTRP2	-0.4486	1.385	-0.4493	43.2594
EoL-1	CTRP2	-0.3423	1.1398	-0.3424	42.5493
Kasumi-1	CTRP2	-0.3092	2.4452	-0.3248	42.3723
Namalwa	CTRP2	-0.0896	2.5342	-0.1036	40.9078
EJM	CTRP2	-0.0811	1.9393	-0.0834	40.8163
OCI-AML-3	CTRP2	0.0524	1.5562	0.0521	39.9205
HuNS1	CTRP2	0.061	2.8213	0.0398	39.9268
RPMI-6666	CTRP2	0.0936	3.4393	0.0336	39.8206
DB	CTRP2	0.1145	4.1522	-0.0258	39.895
MOTN-1	CTRP2	0.2798	2.911	0.2605	38.4655
L-428	CTRP2	0.2802	2.5296	0.2729	38.4255
HD-MY-Z	CTRP2	0.2858	2.9547	0.2648	38.4308
KMS-20	CTRP2	0.5043	3.0956	0.483	36.9775
KO52	CTRP2	0.506	2.7651	0.4966	36.9285
OCI-AML-5	CTRP2	0.5483	3.3163	0.5166	36.7175
697	CTRP2	0.5897	3.5128	0.5463	36.479
SIG-M5	CTRP2	0.5971	2.3475	0.5954	36.296
Hs 611.T	CTRP2	0.7464	2.9623	0.7359	35.3309
MOLP-8	CTRP2	0.9305	2.7684	0.9268	34.0817
JJN-3	CTRP2	1.0507	2.2138	1.0507	33.2687
HEL 92.1.7	CTRP2	1.2368	3.8592	1.195	32.1679
NU-DHL-1	CTRP2	1.2486	5.2612	1.0018	32.7549
LP-1	CTRP2	1.2691	5.5109	0.9683	32.7906
AML-193	CTRP2	1.7144	5.4704	1.4624	29.6954
HuT 78	CTRP2	1.8052	3.1426	1.804	28.246
Kasumi-2	CTRP2	1.8847	5.1866	1.7069	28.315
K-562	CTRP2	1.9042	3.7411	1.8924	27.622
Granta-519	CTRP2	2.0179	4.4678	1.9592	27.023
SUP-B15	CTRP2	2.1774	4.8418	2.0814	26.0879
BL-70	CTRP2	2.1951	5.5575	1.9658	26.4303
Ci-1	CTRP2	3.1989	6.5347	2.7925	20.398
HL-60	CTRP2	4.1839	7.3287	3.5612	14.6922
OCI-M1	CTRP2	4.7266	8.8258	3.4457	13.7562
OCI-Ly10	CTRP2	5.3881	8.2732	4.3449	8.5201
BL-41	CTRP2	5.4829	24.3493	-3.5801	31.8001
OCI-Ly3	CTRP2	5.856	6.5949	5.5998	2.2672
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⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug

Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE15	CTRP2	0.0497	2.5867	0.0369	39.9773
TE-5	CTRP2	-0.3058	1.8793	-0.3091	42.3159
EC-GI-10	CTRP2	0.034	3.0264	0.0014	40.139
TE-11	CTRP2	0.1354	1.7634	0.1349	39.368
OE21	CTRP2	0.1468	2.5315	0.1374	39.3204
KYSE-520	CTRP2	0.4686	2.5673	0.463	37.1653
KYSE-150	CTRP2	0.6803	2.8811	0.6709	35.7673
KYSE-450	CTRP2	0.7459	2.4504	0.7442	35.3049
OE33	CTRP2	0.8048	3.8674	0.7413	35.1125
KYSE-30	CTRP2	1.3863	2.8895	1.3848	31.0379
OE19	CTRP2	1.4553	3.0021	1.4533	30.5798
TE-14	CTRP2	1.7045	3.1544	1.7026	28.9192
KYSE-510	CTRP2	6.403	13.6052	2.5585	13.7748
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⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug

Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
N2a-PK1	CTRP2	0.4541	2.1605	0.453	37.2471
DAN-G	CTRP2	-0.4565	1.8443	-0.4607	43.322
PK-45H	CTRP2	-0.2994	1.9044	-0.303	42.2741
Hs 766T	CTRP2	-0.2098	3.6058	-0.302	41.903
PaTu 8988t	CTRP2	-0.092	2.3054	-0.0998	40.9053
SW1990	CTRP2	-0.0303	1.8284	-0.0316	40.4747
Panc 04.03	CTRP2	0.5202	2.2743	0.5186	36.8081
AsPC-1	CTRP2	1.1131	2.6085	1.1121	32.8564
Panc 03.27	CTRP2	1.3655	2.4943	1.3654	31.1718
KP-2	CTRP2	1.3664	2.3723	1.3664	31.1655
MIA PaCa-2	CTRP2	1.489	3.6503	1.47	30.4124
Panc 10.05	CTRP2	1.5275	2.7304	1.5273	30.0928
PSN1	CTRP2	1.6512	4.8052	1.5226	29.7003
Panc 08.13	CTRP2	1.6608	4.4749	1.5799	29.4757
HuP-T3	CTRP2	2.4762	5.2706	2.331	24.2681
Panc 02.03	CTRP2	2.6638	5.7647	2.4275	23.3398
PaTu 8988s	CTRP2	2.6799	7.8257	1.7689	25.6348
Capan-2	CTRP2	4.5664	10.2835	2.595	17.5336
Capan-1	CTRP2	5.4208	9.6842	3.6819	11.1958
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⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug

Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SH4	CTRP2	5.3157	7.9312	4.4414	9.5775
Hs 688(A).T	CTRP2	-1.3502	5.8442	-1.9717	49.3989
COLO 829	CTRP2	-0.7161	1.662	-0.7203	45.0498
Hs 895.T	CTRP2	-0.4199	2.5595	-0.4427	43.1258
MeWo	CTRP2	-0.2594	1.6492	-0.2607	42.0008
CJM [Human melanoma]	CTRP2	-0.0911	1.4517	-0.0913	40.8762
LOX-IMVI	CTRP2	0.1066	2.5867	0.0949	39.5952
RVH-421	CTRP2	0.4935	1.8126	0.4933	36.9815
WM266-4	CTRP2	0.5211	2.0247	0.5207	36.7983
WM88	CTRP2	0.5839	2.5251	0.5803	36.3906
K029AX	CTRP2	0.811	3.2175	0.7927	34.926
COLO 792	CTRP2	0.8324	2.3455	0.8316	34.7257
HT-144	CTRP2	0.9189	2.5032	0.9177	34.1506
IGR-39	CTRP2	1.0459	5.97	0.6095	34.6545
WM983B	CTRP2	1.0747	3.2929	1.0601	33.157
Hs 839.T	CTRP2	1.1121	3.3296	1.097	32.9097
UACC-62	CTRP2	1.2497	2.3338	1.2496	31.9431
UACC-257	CTRP2	1.4095	2.8207	1.4085	30.8817
Hs 294T	CTRP2	1.5507	3.7432	1.5289	30.0105
SK-MEL-2	CTRP2	1.6941	2.0445	1.6941	28.9822
A101D	CTRP2	2.0379	5.3114	1.8481	27.3379
WM115	CTRP2	2.0927	4.5871	2.0249	26.5557
Hs 940.T	CTRP2	2.1863	4.786	2.0988	25.9992
A2058	CTRP2	2.3779	4.8132	2.2997	24.6916
HMCB	CTRP2	2.447	6.7306	1.9117	25.8343
SK-MEL-24	CTRP2	2.461	4.6335	2.4096	24.0466
IGR-37	CTRP2	2.7909	7.5492	1.9934	24.5116
IGR-1	CTRP2	5.2901	6.4642	5.078	5.8014
COLO 800	CTRP2	5.367	11.6131	2.6771	15.3959
WT2-iPS	CTRP2	5.402	8.6645	4.1668	9.2259
SK-MEL-3	CTRP2	5.4321	5.9071	5.4081	4.1613
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⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	CTRP2	1.7224	3.4572	1.7158	28.8158
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Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CHP-212	CTRP2	-0.0395	2.0288	-0.0425	40.5414
SK-N-SH	CTRP2	-0.029	1.9061	-0.0308	40.4677
SK-N-AS	CTRP2	0.8824	3.4069	0.8569	34.4738
SK-N-BE(2)	CTRP2	1.6442	5.116	1.4602	29.9328
NH-6	CTRP2	1.939	5.5853	1.6806	28.2294
SK-N-DZ	CTRP2	2.9914	6.115	2.6931	21.3832
KP-N-YN	CTRP2	4.9373	8.8677	3.6297	12.5051
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⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-869	CTRP2	2.4442	6.7911	1.8887	25.9238
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Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Hs 888.T	CTRP2	-1.5718	2.7387	-1.651	50.7086
Hs 822.T	CTRP2	-0.6769	4.1087	-0.8673	45.1071
MG-63	CTRP2	-0.0302	2.219	-0.0356	40.4864
A-673	CTRP2	0.0087	2.6865	-0.0084	40.2625
SK-N-MC	CTRP2	0.7602	2.4129	0.7588	35.2086
TC71	CTRP2	0.8873	3.6479	0.8465	34.4908
G-292 clone A141B1	CTRP2	1.3869	2.6134	1.3867	31.0296
SaOS-2	CTRP2	1.5042	3.3599	1.4964	30.2736
SK-ES-1	CTRP2	1.7402	3.4849	1.7332	28.6988
HOS	CTRP2	2.4265	6.0008	2.1079	25.2063
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⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug

Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Hs 578Bst	CTRP2	-3.5835	1.1515	-3.6324	63.1708
MDA-MB-157	CTRP2	-0.9965	2.8318	-1.0567	46.9904
MDA-MB-453	CTRP2	-0.1945	3.2681	-0.2535	41.7227
HCC2218	CTRP2	-0.0377	5.4059	-0.4303	41.4359
HCC1500	CTRP2	-0.0358	3.5364	-0.1112	40.7167
HCC38	CTRP2	0.6826	2.6577	0.678	35.7362
SK-BR-3	CTRP2	0.8166	4.598	0.659	35.3267
BT-20	CTRP2	1.044	4.7656	0.8757	33.8573
EFM-192A	CTRP2	1.129	4.0676	1.0629	32.9652
T-47D	CTRP2	1.3502	4.8002	1.1997	31.7722
HCC202	CTRP2	1.4996	4.8623	1.3501	30.7774
CAL-85-1	CTRP2	1.502	3.2666	1.4964	30.2807
BT-549	CTRP2	1.6158	5.4259	1.3651	30.3432
BT-474	CTRP2	1.7982	2.719	1.7981	28.2891
MDA-MB-468	CTRP2	1.8088	5.0318	1.6538	28.7419
HCC1419	CTRP2	1.8233	5.5572	1.5611	29.0091
HCC1428	CTRP2	2.2295	5.9262	1.9128	26.5055
AU565	CTRP2	2.3197	6.3946	1.8787	26.3425
MDA-MB-361	CTRP2	2.3744	8.3999	1.2179	28.4158
Hs 578T	CTRP2	2.4655	5.1808	2.336	24.2849
ZR-75-30	CTRP2	4.6046	10.124	2.7082	16.9988
MDA-MB-415	CTRP2	6.3239	14.0524	2.2708	15.0289
BT 239	CTRP2	-2.8519	0.9567	-2.8722	59.0019
BT 228	CTRP2	-2.175	1.9716	-2.2229	54.5799
BT 216	CTRP2	-2.125	1.3472	-2.1428	54.3474
BT 286	CTRP2	-1.9195	1.7515	-1.9477	52.9881
BT 440	CTRP2	-1.8238	2.2524	-1.8764	52.3353
BT 159	CTRP2	-1.3575	2.6067	-1.4162	49.3336
BT 248	CTRP2	-1.0487	2.3763	-1.0813	47.3001
BT 504	CTRP2	-0.9632	2.0904	-0.981	46.7158
BT 333	CTRP2	-0.6971	3.0368	-0.7602	45.0379
BT 340	CTRP2	-0.1696	2.6831	-0.1911	41.4603
BT 498	CTRP2	0.0145	2.6621	-0.0016	40.2213
BT 224	CTRP2	0.21	3.2946	0.1666	39.0018
BT 232	CTRP2	0.2547	2.2381	0.2517	38.5817
BT 444	CTRP2	0.2625	3.3172	0.2197	38.6514
BT164	CTRP2	0.2938	2.7385	0.2812	38.3516
BT 112	CTRP2	0.4428	2.6124	0.4361	37.3406
BT 328	CTRP2	0.725	4.1615	0.6241	35.7588
BT 330	CTRP2	0.8044	3.0289	0.793	34.947
BT 172	CTRP2	0.9884	3.4361	0.9648	33.762
BT 482	CTRP2	1.0934	3.0479	1.0866	33.0069
BT 131	CTRP2	1.1032	2.3537	1.103	32.9194
BT147	CTRP2	1.1675	2.6053	1.1668	32.493
BT 271	CTRP2	1.2402	2.0837	1.2402	32.0063
BT 422	CTRP2	1.2683	2.7335	1.2673	31.8222
BT 416	CTRP2	1.4788	2.1433	1.4788	30.4164
BT 359	CTRP2	1.9429	3.4222	1.9398	27.3351
BT 245	CTRP2	1.9433	3.7326	1.9328	27.3571
BT 179	CTRP2	1.9678	4.4627	1.9068	27.3645
BT 139	CTRP2	2.0175	3.5349	2.0135	26.8412
BT 145	CTRP2	2.0353	4.7026	1.9492	27.0001
BT 320	CTRP2	2.218	3.9232	2.2068	25.5294
BT 231	CTRP2	2.2353	3.2742	2.235	25.3777
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⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug

Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KG-1-C	CTRP2	-4.511	-0.8412	-4.517	69.5945
U-251MG	CTRP2	-0.9331	1.9166	-0.945	46.5072
Becker	CTRP2	-0.5776	1.1503	-0.578	44.118
T98G	CTRP2	-0.4232	1.7237	-0.4258	43.0959
SF268	CTRP2	0.0032	1.8238	0.0021	40.2509
TM-31	CTRP2	0.0379	2.5821	0.025	40.0562
A-172	CTRP2	0.3381	2.4793	0.3326	38.0341
42-MG-BA	CTRP2	0.3616	2.3812	0.3579	37.8717
YKG-1	CTRP2	0.4841	3.2808	0.4522	37.1455
YH-13	CTRP2	0.7058	2.7349	0.7002	35.585
GMS-10	CTRP2	0.7581	2.3305	0.7572	35.221
DK-MG	CTRP2	0.7789	3.3329	0.7541	35.1605
SNB-75	CTRP2	0.8391	2.3477	0.8384	34.6806
KNS-42	CTRP2	1.4053	2.8155	1.4044	30.9092
D283 Med	CTRP2	1.4208	3.529	1.4054	30.8545
M059K	CTRP2	1.6212	2.9394	1.6204	29.4705
8-MG-BA	CTRP2	1.7223	2.5785	1.7222	28.7948
U-118MG	CTRP2	1.7399	4.6873	1.6356	29.0282
CCF-STTG1	CTRP2	1.7503	4.9352	1.6077	29.0888
GOS-3	CTRP2	2.0115	3.5769	2.0065	26.8844
SF539	CTRP2	2.2209	3.7624	2.2149	25.493
Hs 683	CTRP2	2.2651	4.382	2.2277	25.3042
SW1783	CTRP2	3.171	10.315	1.2125	26.1227
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⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug

Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
AN3-CA	CTRP2	-1.4625	-0.268	-1.4625	50.0123
JHUEM-1	CTRP2	-0.4695	2.4083	-0.4875	43.4431
JHUEM-7	CTRP2	-0.434	2.5169	-0.4554	43.2159
MFE-296	CTRP2	-0.1761	2.071	-0.1808	41.4561
HEC-1-A	CTRP2	0.6487	3.2272	0.6253	36.023
JHUEM-3	CTRP2	0.9277	3.4854	0.8994	34.1815
EN	CTRP2	1.0137	3.5278	0.9859	33.6071
ESS-1	CTRP2	1.0894	2.6842	1.0879	33.0159
MFE-319	CTRP2	1.6284	4.5713	1.5327	29.7412
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Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
UO-31	CTRP2	-1.6648	0.3293	-1.6652	51.3591
KMRC-1	CTRP2	0.0231	1.8	0.0221	40.118
786-O	CTRP2	0.3494	2.1201	0.348	37.9454
ACHN	CTRP2	0.3676	2.0009	0.3669	37.822
Caki-1	CTRP2	1.2138	2.5452	1.2133	32.1838
TUHR14TKB	CTRP2	1.3664	7.2636	0.5609	59.5928
RCC10RGB	CTRP2	1.5698	3.2509	1.5654	29.8252
CAL-54	CTRP2	1.8054	4.0236	1.7755	28.3409
VMRC-RCZ	CTRP2	1.8383	2.8463	1.8382	28.022
Caki-2	CTRP2	3.1942	5.9125	2.9689	19.7724
KMRC-2	CTRP2	4.8616	5.9418	4.78	8.1631
KMRC-3	CTRP2	7.535	20.783	-0.1225	20.6623
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Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SW948	CTRP2	-0.2504	3.2689	-0.3121	42.0983
COLO 678	CTRP2	0.0902	2.8922	0.0664	39.7404
HCT 8	CTRP2	0.3173	2.0419	0.3162	38.1582
GP2d	CTRP2	0.4446	2.5834	0.4384	37.3271
SW1417	CTRP2	1.1228	3.349	1.1072	32.84
T84	CTRP2	1.5075	3.8764	1.4759	30.3309
NCI-H716	CTRP2	1.6719	4.6033	1.5748	29.4565
SNU-503	CTRP2	1.8583	5.2034	1.6751	28.5088
NCI-H747	CTRP2	1.8795	4.1539	1.8431	27.869
SNU-C4	CTRP2	1.9699	2.7903	1.9699	27.1449
SNU-1033	CTRP2	2.112	10.9766	-0.1563	33.1302
HCC-56	CTRP2	2.1503	3.147	2.1501	25.9436
SNU-C1	CTRP2	2.3667	6.9929	1.7368	26.6915
C2BBe1	CTRP2	2.8637	9.6009	1.2209	26.9603
RCM-1 [Human ESC]	CTRP2	2.9854	6.9543	2.4197	22.3947
COLO 320	CTRP2	3.2257	7.4896	2.4808	21.4724
HCT 15	CTRP2	4.2828	6.4778	3.9883	12.7891
LS1034	CTRP2	4.6353	11.6622	1.9893	19.6742
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Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHH-2	CTRP2	-1.4491	-0.1077	-1.4491	49.9225
SNU-423	CTRP2	-1.2039	0.1524	-1.204	48.2895
SNU-387	CTRP2	-0.0929	2.4657	-0.1048	40.9235
SK-HEP-1	CTRP2	0.2947	1.5765	0.2946	38.3058
JHH-5	CTRP2	1.0786	3.9224	1.024	33.2629
SNU-449	CTRP2	1.2864	2.8594	1.2845	31.7047
HuH-1	CTRP2	1.37	4.8131	1.2188	31.6433
PLC/PRF/5	CTRP2	1.6354	3.3441	1.6301	29.391
JHH-6	CTRP2	1.6904	2.3775	1.6904	29.0071
JHH-4	CTRP2	1.7129	4.3982	1.6442	29.0878
HLF	CTRP2	1.7591	2.8448	1.7589	28.5499
JHH-1	CTRP2	5.2373	9.6855	3.5141	12.2912
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Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HCC4006	CTRP2	-1.7675	-0.3765	-1.7675	52.0441
NCI-H1703	CTRP2	-1.1935	0.1661	-1.1936	48.2202
HCC2935	CTRP2	-0.8979	1.5688	-0.9025	46.2604
NCI-H841	CTRP2	-0.6328	1.8378	-0.6387	44.4999
HOP-62	CTRP2	-0.6272	2.1692	-0.6406	44.48
NCI-H522	CTRP2	-0.6077	0.741	-0.6077	44.3172
HOP-92	CTRP2	-0.4314	2.4648	-0.4506	43.1934
NCI-H1693	CTRP2	-0.2493	1.6227	-0.2504	41.9331
NCI-H1915	CTRP2	-0.2284	1.7674	-0.2302	41.7957
NCI-H647	CTRP2	-0.2066	2.6121	-0.2261	41.7012
NCI-H838	CTRP2	-0.1255	1.716	-0.1266	41.1081
NCI-H520	CTRP2	-0.0805	2.0302	-0.0838	40.8155
NCI-H2196	CTRP2	-0.0062	2.6156	-0.0211	40.3555
NCI-H1651	CTRP2	0.004	12.1721	-2.8424	44.2649
Lu-65	CTRP2	0.4473	1.8062	0.4472	37.2891
NCI-H1793	CTRP2	0.4704	3.0731	0.4492	37.2029
Calu-1	CTRP2	0.5853	2.0427	0.585	36.3703
RERF-LC-MS	CTRP2	0.6589	2.2115	0.6582	35.8815
LC-1/sq-SF	CTRP2	0.6604	2.8297	0.652	35.8965
NCI-H2110	CTRP2	0.7562	3.5995	0.7134	35.3699
RERF-LC-Ad2	CTRP2	0.7568	3.3205	0.732	35.3078
COR-L51	CTRP2	0.8422	3.1388	0.8279	34.705
HCC1438	CTRP2	0.9694	2.7546	0.9663	33.8207
NCI-H1341	CTRP2	0.9799	3.1387	0.9686	33.7781
NCI-H2342	CTRP2	1.0653	3.787	1.0216	33.3156
NCI-H1339	CTRP2	1.0672	3.6388	1.0343	33.2676
NCI-H1563	CTRP2	1.2043	4.1199	1.1369	32.4689
NCI-H322	CTRP2	1.282	2.3314	1.2819	31.728
SK-MES-1	CTRP2	1.3552	3.9785	1.3091	31.3939
COR-L105	CTRP2	1.3768	3.1743	1.3714	31.1143
NCI-H2081	CTRP2	1.409	3.1483	1.4045	30.8967
NCI-H1694	CTRP2	1.4119	4.0453	1.3627	31.0263
T3M-10	CTRP2	1.4705	4.2965	1.3991	30.7107
NCI-H1395	CTRP2	1.6318	5.6373	1.3336	30.3951
NCI-H1105	CTRP2	1.7884	3.4587	1.7828	28.3729
COLO 668	CTRP2	1.8093	4.2165	1.7643	28.3656
DMS 114	CTRP2	1.8186	5.2494	1.6229	28.8148
DMS 273	CTRP2	1.8394	3.2234	1.8378	28.0194
EKVX	CTRP2	2.0134	4.3137	1.9698	27.0014
DV-90	CTRP2	2.0363	5.559	1.7926	27.5338
NCI-H23	CTRP2	2.0722	5.3319	1.8811	27.1145
NCI-H810	CTRP2	2.2391	5.0825	2.1091	25.7937
KNS-62	CTRP2	2.2615	3.6068	2.2589	25.2108
ChaGo-K-1	CTRP2	2.3037	5.6975	2.0513	25.7891
COR-L95	CTRP2	2.5467	4.5251	2.5104	23.4243
VMRC-LCD	CTRP2	2.6188	7.2797	1.9083	25.3259
NCI-H1568	CTRP2	2.6831	5.4976	2.5097	22.9895
NCI-H1869	CTRP2	2.939	8.1324	1.9221	24.3355
NCI-H2170	CTRP2	2.9425	7.7056	2.0953	23.702
LUDLU-1	CTRP2	2.9967	6.5372	2.5718	21.8062
DMS 454	CTRP2	3.1445	5.3172	3.0444	19.6616
DMS 53	CTRP2	3.7285	6.6574	3.3265	16.8679
NCI-H2029	CTRP2	4.1436	11.0027	1.8455	21.3869
LK2	CTRP2	4.2264	8.934	2.9013	17.1675
NCI-H1944	CTRP2	5.8263	12.2555	2.7553	14.128
NCI-H1623	CTRP2	6.1034	13.2332	2.499	14.5819
Hs 888.Lu	CTRP2	-2.7225	0.6706	-2.733	58.2624
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Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	-2.2754	-0.1748	-2.2757	55.4227
JHOM-1	CTRP2	-2.0008	-1.0971	-2.0008	53.5984
TOV-112D	CTRP2	-0.8818	1.3545	-0.8841	46.1487
OV7	CTRP2	-0.4157	2.5145	-0.4365	43.0931
OV-90	CTRP2	0.0172	1.6294	0.0168	40.1551
TOV-21G	CTRP2	0.6252	2.5355	0.6218	36.1146
COV362	CTRP2	0.711	3.7081	0.6574	35.7044
EFO-27	CTRP2	0.7459	4.1813	0.6438	35.624
OC 314	CTRP2	0.8711	2.6405	0.8685	34.4739
EFO-21	CTRP2	1.2935	3.5046	1.2758	31.7101
OVCAR-5	CTRP2	1.613	4.2554	1.5541	29.7202
COV434	CTRP2	1.6723	3.6557	1.6582	29.1747
OAW42	CTRP2	1.9603	2.6364	1.9603	27.2087
JHOS-2	CTRP2	2.9648	6.46	2.5616	21.9389
COV644	CTRP2	3.3573	7.9661	2.4306	21.2875
OAW28	CTRP2	3.635	7.5428	2.895	18.7614
OV56	CTRP2	3.7905	7.5435	3.0591	17.7042
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Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Yamato-SS	CTRP2	-0.7885	3.9612	-0.9645	45.7958
Aska-SS	CTRP2	0.934	4.0506	0.8587	34.2914
TE 441.T	CTRP2	-1.7291	-0.9812	-1.7291	51.788
G-401	CTRP2	-1.3583	-0.3167	-1.3583	49.3177
G-402	CTRP2	-1.0037	0.6591	-1.0039	46.9559
A-204	CTRP2	-0.7304	1.4387	-0.7325	45.1402
HT-1080	CTRP2	-0.2972	2.4228	-0.3119	42.2902
TTC-709	CTRP2	-0.1779	2.5771	-0.1953	41.5042
BT-12	CTRP2	-0.1246	1.5	-0.1249	41.0997
TE 617.T	CTRP2	0.2776	2.2763	0.2744	38.4294
SK-LMS-1	CTRP2	0.5585	1.9994	0.5582	36.549
SK-UT-1	CTRP2	0.8165	4.405	0.6886	35.2362
GCT	CTRP2	1.0965	2.3087	1.0964	32.9638
MES-SA	CTRP2	1.099	2.4019	1.0987	32.9481
SW982	CTRP2	1.5355	4.9019	1.3819	30.5525
KYM-1	CTRP2	1.6265	2.497	1.6265	29.4329
Hs 729.T	CTRP2	1.7588	4.9054	1.6219	29.0128
BT-16	CTRP2	1.7871	2.9511	1.7868	28.3638
Tm87-16	CTRP2	1.8005	4.526	1.722	28.5374
RD	CTRP2	1.9755	5.3333	1.7759	27.7864
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Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-CH1	CTRP2	1.0089	4.2764	0.9115	33.8647
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Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
H-STS	CTRP2	1.5597	3.519	1.5481	29.9164
SYO-1	CTRP2	1.8276	4.984	1.6826	28.5829
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Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JL-1	CTRP2	0.7897	2.6832	0.7858	35.0206
MPP 89	CTRP2	2.0235	3.1594	2.023	26.7894
IST-Mes1	CTRP2	2.21	4.6626	2.1403	25.7809
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Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H660	CTRP2	-1.7862	4.2426	-2.0855	51.9038
LNCaP clone FGC	CTRP2	0.0627	2.5454	0.0514	39.8861
PaCa-3	CTRP2	0.3694	2.4357	0.3649	37.8222
DU145	CTRP2	0.4584	2.6579	0.4509	37.2393
VCaP	CTRP2	2.6872	5.8403	2.4342	23.2432
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Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
A-253	CTRP2	0.965	2.6507	0.9629	33.8466
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Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KE-39	CTRP2	-1.2256	2.4971	-1.2714	48.4707
NCC-StC-K140	CTRP2	-0.5522	2.5117	-0.5766	44.007
SNU-1	CTRP2	-0.085	1.931	-0.0873	40.8422
Hs 746.T	CTRP2	0.0245	1.6894	0.024	40.1069
SNU-216	CTRP2	0.3542	2.6128	0.3461	37.9352
HGC-27	CTRP2	0.3642	3.1532	0.3356	37.9326
SH-10-TC	CTRP2	0.6033	1.8609	0.6032	36.2495
LMSU	CTRP2	0.7794	2.6472	0.7759	35.0879
MKN74	CTRP2	1.4805	5.3954	1.2247	31.2542
HuG1-N	CTRP2	2.1205	6.2207	1.7128	27.5411
MKN7	CTRP2	2.3764	5.8463	2.0938	25.4122
KATO III	CTRP2	3.0918	5.0921	3.0233	19.9031
SNU-601	CTRP2	3.2215	8.926	1.8835	44.3853
SNU-16	CTRP2	4.4377	8.8302	3.1594	15.6153
IM95	CTRP2	5.334	6.8123	4.9787	6.0707
SNU-685	CTRP2	1.5702	4.077	1.5259	29.9559
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Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
FTC-133	CTRP2	-0.7816	1.9463	-0.7918	45.4985
SW579	CTRP2	0.0934	2.7953	0.074	39.7061
TT2609-C02	CTRP2	0.6347	2.6335	0.63	36.0556
FTC-238	CTRP2	1.371	2.6823	1.3705	31.1366
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Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SCC-4	CTRP2	-0.5397	2.1117	-0.5499	43.8908
PE/CA-PJ15	CTRP2	0.1714	2.2942	0.167	39.141
BICR 22	CTRP2	0.4159	2.3273	0.4132	37.5065
PE/CA-PJ49	CTRP2	0.5399	2.4813	0.5365	36.683
SCC-9	CTRP2	0.7205	2.8776	0.7118	35.4973
BICR 6	CTRP2	0.9016	4.1231	0.8162	34.5389
HSC-2	CTRP2	1.194	2.7074	1.1928	32.3182
PE/CA-PJ34 (clone C12)	CTRP2	1.5265	3.21	1.5223	30.113
FaDu	CTRP2	1.6522	3.169	1.6498	29.2694
PE/CA-PJ41 (clone D2)	CTRP2	1.9591	5.1799	1.7887	27.7952
BICR 31	CTRP2	2.1589	4.7487	2.0747	26.1705
CAL-33	CTRP2	2.194	3.3315	2.1934	25.6538
BICR 56	CTRP2	2.2213	4.8001	2.1342	25.7649
CAL-27	CTRP2	2.5581	4.8805	2.4827	23.4816
BICR 16	CTRP2	2.8206	5.8717	2.5718	22.3413
BICR 18	CTRP2	4.2119	7.929	3.3372	15.4899
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Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KMBC-2	CTRP2	-2.2015	2.1222	-2.2602	54.7173
U-BLC1	CTRP2	-0.3118	3.4895	-0.3975	42.5576
T24	CTRP2	0.7747	2.6155	0.7716	35.1177
BC-3C	CTRP2	1.1948	3.7116	1.1621	32.4172
SCaBER	CTRP2	1.1983	2.8922	1.1954	32.295
HT-1197	CTRP2	1.7329	6.8913	1.0833	30.8736
647V	CTRP2	1.7695	4.0718	1.7347	28.5966
UM-UC-1	CTRP2	1.7816	4.2111	1.7357	28.5534
J82	CTRP2	5.5307	6.1614	5.448	3.7176
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References

1	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.