Details of the Drug

General Information of Drug (ID: DM51JW4)

Drug Name
Aducanumab
Synonyms BIIB037
Indication
Disease Entry ICD 11 Status REF
Alzheimer disease 8A20 Approved [1]
ATC Code
N06DX03: Aducanumab
N06DX: Other anti-dementia drugs
N06D: ANTI-DEMENTIA DRUGS
N06: PSYCHOANALEPTICS
N: NERVOUS SYSTEM
Cross-matching ID
UNII
105J35OE21
DrugBank ID
DB12274
TTD ID
D00RRU

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Amyloid beta A4 protein (APP) TTE4KHA A4_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Alzheimer disease
ICD Disease Classification 8A20
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Amyloid beta A4 protein (APP) DTT APP 1.60E-02 -0.07 -0.31
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 761178.
2 Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets . Immun Ageing. 2013; 10: 18.