Details of the Drug

General Information of Drug (ID: DM52NOI)

Drug Name
NSC-656158
Synonyms
CHM-1; NSC-656158; 154554-41-3; CHM 1; CHM-1 hydrate; CHEMBL280099; 6-(2-Fluorophenyl)[1,3]dioxolo[4,5-G]quinolin-8(5h)-One; 1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-; NSC656158; AC1Q4OOR; AC1L8C3G; Neuro_000375; SCHEMBL338729; CTK7C2351; AOB2618; DTXSID80327429; MolPort-009-194-114; HMS3262E04; ZINC5581788; KS-00002WS1; Tox21_500741; BDBM50041119; AKOS015994545; LP00741; CE-0108; NCGC00261426-01; NCGC00186026-01; NCI60_019422; J-009113; 1,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-; BRD-K94145482-001-02-8
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 283.25
Logarithm of the Partition Coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C16H10FNO3
IUPAC Name
6-(2-fluorophenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one
Canonical SMILES
C1OC2=C(O1)C=C3C(=C2)C(=O)C=C(N3)C4=CC=CC=C4F
InChI
InChI=1S/C16H10FNO3/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12/h1-7H,8H2,(H,18,19)
InChIKey
ZMYDAPJHGNEFGQ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
375860
CAS Number
154554-41-3
TTD ID
D0B4CA

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type A (MAO-A) TT3WG5C AOFA_HUMAN Inhibitor [1]
Stress-activated protein kinase JNK3 (JNK3) TT056SO MK10_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type A (MAO-A) DTT MAOA 8.14E-01 0.05 0.1
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 151 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -0.6286 1.7997 -0.6616 30.9779
MEC1 CTRP2 -0.5329 0.3215 -0.5329 30.2297
JM1 CTRP2 -0.7164 0.9414 -0.7193 31.4631
MOLM-16 CTRP2; CTRP1 -2.9668 -1.2883 -2.967 46.4615
SU-DHL-5 CTRP1 -2.576 -1.9029 -2.576 92.9647
Pfeiffer CTRP2 -2.5034 0.0343 -2.5116 43.393
697 CTRP2 -2.4833 -0.3726 -2.4856 43.2432
NU-DUL-1 CTRP2; CTRP1 -2.3119 -1.412 -2.3119 42.0937
DB CTRP2 -2.2181 0.7412 -2.2444 41.543
AMO1 CTRP2; CTRP1 -2.1497 -0.4917 -2.1502 41.0134
HuT 78 CTRP2 -2.1449 8.0322 -4.1169 43.9872
ALL-SIL CTRP2 -2.0807 0.5855 -2.0968 40.6004
SUP-M2 CTRP2 -1.9998 0.8884 -2.0269 40.094
NB4 CTRP2 -1.9518 -1.264 -1.9518 39.6922
WSU-DLCL2 CTRP2; CTRP1 -1.9469 -1.0365 -1.9469 39.6596
KMS-26 CTRP2 -1.7652 -1.0858 -1.7652 38.448
KMS-21-BM CTRP2 -1.7617 -0.7516 -1.7617 38.4246
KE-97 CTRP2 -1.6823 0.0723 -1.6836 37.8992
EB1 CTRP2 -1.6398 2.1965 -1.7727 38.008
NU-DHL-1 CTRP2 -1.6381 0.4332 -1.6428 37.6154
PL21 CTRP2; CTRP1 -1.6202 -0.4786 -1.6203 37.481
P31/FUJ CTRP2 -1.5774 -1.0631 -1.5774 37.1955
A4/Fukuda CTRP2 -1.5717 0.6415 -1.5796 37.183
KMS-34 CTRP2 -1.5379 -0.6271 -1.5379 36.9316
Peer CTRP2 -1.5252 -0.9091 -1.5252 36.847
JVM-3 CTRP2 -1.5093 0.1608 -1.5104 39.329
KMS-11 CTRP2; CTRP1 -1.5061 0.2723 -1.5079 36.7259
DEL CTRP2 -1.4809 -1.1587 -1.4809 36.5517
JURL-MK1 CTRP2 -1.4738 -0.5352 -1.4738 36.5045
F-36P CTRP2 -1.4496 0.5013 -1.4534 36.3556
P12-Ichikawa CTRP2 -1.4352 -0.8163 -1.4352 36.2469
OCI-AML-3 CTRP2; CTRP1 -1.429 -0.0284 -1.4293 36.2065
OCI-Ly3 CTRP2 -1.4221 0.0172 -1.4224 36.1606
MV4-11 CTRP2 -1.4099 -0.3712 -1.4099 36.078
MOLM-13 CTRP2 -1.4094 0.046 -1.4098 36.076
EoL-1 CTRP2 -1.4046 -0.4189 -1.4046 36.0428
KE-37 CTRP2 -1.395 -0.7012 -1.395 35.979
KO52 CTRP2 -1.3875 0.2238 -1.3884 35.9317
U-937 CTRP2; CTRP1 -1.3864 -0.1633 -1.3864 35.9214
KMS-27 CTRP2 -1.3708 -0.8778 -1.3708 35.8171
HT CTRP2 -1.3376 -0.8863 -1.3376 35.5963
MOLT-3 CTRP2 -1.3342 0.0008 -1.3344 35.5741
MOLP-8 CTRP2 -1.3148 3.3993 -1.6479 36.4416
RS4;11 CTRP2 -1.2971 0.4412 -1.299 35.3322
SKM-1 CTRP2; CTRP1 -1.2913 -0.0673 -1.2914 35.2874
GA-10 CTRP2 -1.2343 0.5096 -1.2364 34.914
THP-1 CTRP2; CTRP1 -1.2254 0.7088 -1.2301 34.8634
EJM CTRP2; CTRP1 -1.2137 1.1432 -1.2302 34.8239
CMK CTRP2 -1.1866 1.6393 -1.2314 34.7357
KM-H2 CTRP2 -1.1843 0.5613 -1.1866 34.5814
SEM CTRP2 -1.1592 0.0362 -1.1593 34.4065
RPMI-8402 CTRP2 -1.1492 0.1465 -1.1494 34.3401
Granta-519 CTRP2 -1.1314 0.9023 -1.1386 34.245
Karpas-299 CTRP2 -1.131 0.2944 -1.1315 34.2201
MOLM-6 CTRP2 -1.1184 0.8429 -1.1241 34.1531
NOMO-1 CTRP2; CTRP1 -1.0872 0.1445 -1.0873 33.9264
U266B1 CTRP2 -1.0618 1.9228 -1.1257 33.9665
OPM-2 CTRP2 -1.0276 -0.164 -1.0276 33.5286
Kasumi-2 CTRP2 -1.0156 1.3294 -1.0348 33.5124
Daudi CTRP2 -1.0054 1.1014 -1.0158 33.4152
RPMI-8226 CTRP2; CTRP1 -0.9975 0.3353 -0.9978 33.329
HH [Human lymphoma] CTRP2 -0.9941 1.3674 -1.0146 33.3732
L-428 CTRP2 -0.9927 2.073 -1.0685 33.5447
M-07e CTRP2 -0.9054 1.6085 -0.9364 32.8168
Namalwa CTRP2 -0.893 0.5729 -0.8939 32.6341
BV-173 CTRP2 -0.8927 0.7555 -0.8949 32.6362
HuNS1 CTRP2 -0.8629 1.1089 -0.8708 32.4568
BL-70 CTRP2 -0.8614 0.6219 -0.8624 32.4238
MOLT-16 CTRP2 -0.848 -0.0938 -0.848 32.331
GDM-1 CTRP2; CTRP1 -0.8161 1.7926 -0.8565 32.2526
ST486 CTRP2 -0.804 0.8808 -0.807 32.0475
Ki-JK CTRP2 -0.7917 1.9589 -0.845 32.1325
NALM-6 CTRP2 -0.7589 0.289 -0.759 31.737
SU-DHL-4 CTRP2; CTRP1 -0.727 0.2766 -0.727 31.524
KCL-22 CTRP2 -0.7143 0.2752 -0.7143 31.4394
MJ CTRP2 -0.7143 0.8811 -0.7165 31.4467
Mino CTRP2 -0.7058 -0.1099 -0.7058 31.3824
Jurkat CTRP2 -0.7007 0.8276 -0.7023 31.354
A3/Kawakami CTRP2 -0.6917 0.582 -0.6921 31.2898
SUP-B15 CTRP2 -0.6868 0.5489 -0.6871 31.257
Ku812 CTRP2 -0.6565 0.8244 -0.6579 31.0585
OCI-Ly19 CTRP2 -0.6461 0.7383 -0.6469 30.9871
CA46 CTRP2 -0.6257 1.9524 -0.6704 30.9978
L-540 CTRP2 -0.6247 0.7738 -0.6256 30.845
JJN-3 CTRP2 -0.6223 0.4049 -0.6223 30.8258
SUP-HD1 CTRP2 -0.6148 2.7043 -0.7509 31.2294
Kasumi-1 CTRP2 -0.6002 0.5665 -0.6004 30.6788
JeKo-1 CTRP2 -0.5982 0.7603 -0.5989 30.6675
MOTN-1 CTRP2 -0.5934 2.3569 -0.6785 30.9173
HPB-ALL CTRP2 -0.5885 0.3221 -0.5886 30.6006
SUP-T1 CTRP2 -0.5618 1.6887 -0.5853 30.5008
HL-60 CTRP2 -0.5612 0.1053 -0.5612 30.418
SU-DHL-6 CTRP2 -0.5597 0.8562 -0.5608 30.4122
MOLT-13 CTRP2 -0.5472 0.352 -0.5472 30.3248
PF-382 CTRP2 -0.4905 1.8219 -0.5196 30.0439
OCI-AML-5 CTRP2 -0.4844 -0.0491 -0.4844 29.9064
RPMI-6666 CTRP2 -0.4639 0.1341 -0.4639 29.7696
SU-DHL-8 CTRP2 -0.449 0.7617 -0.4494 29.6714
K-562 CTRP2 -0.4434 0.4185 -0.4434 29.6327
HEL CTRP2 -0.4433 0.5327 -0.4433 29.6322
CML-T1 CTRP2 -0.434 2.1602 -0.488 29.751
OCI-AML-2 CTRP2 -0.4323 -0.0129 -0.4323 29.5589
SU-DHL-1 CTRP2 -0.4291 2.6312 -0.5404 29.911
SIG-M5 CTRP2 -0.4145 0.0318 -0.4145 29.4397
OCI-M1 CTRP2 -0.4142 0.7787 -0.4146 29.4393
SET-2 CTRP2 -0.4089 0.7259 -0.4091 29.4031
SU-DHL-10 CTRP2 -0.4049 0.3277 -0.4049 29.376
LAMA-84 CTRP2 -0.3859 1.1877 -0.389 29.2597
HDLM-2 CTRP2 -0.3648 2.7261 -0.4858 29.5156
KHM-1B CTRP2 -0.3643 0.8043 -0.3646 31.1533
L-363 CTRP2 -0.3621 0.2522 -0.3621 29.0905
JVM-2 CTRP2 -0.3542 1.642 -0.3691 29.0876
Hs 611.T CTRP2 -0.3343 0.9087 -0.3348 28.9066
Karpas-422 CTRP2 -0.3298 1.5139 -0.3393 28.9068
RL CTRP2 -0.3205 1.8672 -0.3462 28.8992
SR CTRP2 -0.3089 1.3349 -0.3136 28.7515
LP-1 CTRP2; CTRP1 -0.2935 3.6798 -0.6022 29.6739
HEL 92.1.7 CTRP2 -0.2915 1.4753 -0.2992 28.6454
RCH-ACV CTRP2 -0.2701 0.9231 -0.2706 28.4786
Ci-1 CTRP2 -0.2651 1.3592 -0.2697 28.4588
EM-2 CTRP2 -0.2637 1.4766 -0.271 28.4588
MM1.S CTRP2 -0.2509 1.5751 -0.2608 28.3819
MC116 CTRP2 -0.2415 0.2168 -0.2415 28.286
EHEB CTRP2 -0.2324 2.7205 -0.343 28.5991
AML-193 CTRP2 -0.1566 4.723 -0.7524 29.7274
KYO-1 CTRP2 -0.1194 1.098 -0.12 27.474
Ri-1 CTRP2 -0.0891 1.7537 -0.1018 27.3123
MOLP-2 CTRP2 -0.0368 2.946 -0.1689 27.3694
KMS-20 CTRP2 0.0583 2.9373 -0.0651 26.7064
TF-1 CTRP2 0.0808 2.6288 0.0044 26.395
HD-MY-Z CTRP2 0.1197 3.685 -0.1531 26.8137
NCI-H929 CTRP2 0.2486 2.4939 0.1979 25.1887
MHH-CALL-4 CTRP2 0.3168 2.6044 0.2579 24.7619
KMS-18 CTRP2 0.3646 1.4634 0.3639 24.2465
SK-MM-2 CTRP2 0.3904 2.3294 0.3614 24.1695
TALL-1 [Human adult T-ALL] CTRP2 0.6916 3.5168 0.509 22.6928
DND-41 CTRP2 0.7181 4.7247 0.1972 23.7277
Mono-Mac-1 CTRP2 0.7304 3.7912 0.4866 22.651
OCI-Ly10 CTRP2; CTRP1 0.7439 3.307 0.6089 22.1777
SUP-T11 CTRP2 0.8289 3.8279 0.5847 21.9967
ME1 CTRP2 1.2764 4.8399 0.7623 20.0077
MHH-CALL-3 CTRP2 1.4036 5.5771 0.6211 20.1728
Reh CTRP2 2.5522 3.9325 2.4378 10.054
Raji CTRP2 2.647 3.8897 2.552 9.3528
Mono-Mac-6 CTRP2 2.7719 8.5816 0.6196 16.6923
Toledo CTRP2 3.2114 11.0934 -0.2236 18.9043
BL-41 CTRP2 3.9428 10.7273 0.5885 14.3025
P3HR-1 CTRP2 4.0351 9.1571 1.4507 10.6343
Karpas-620 CTRP2 5.6392 6.8503 3.604 0.1832
REC-1 CTRP2 5.7034 8.2676 3.0628 1.626
KMM-1 CTRP2 6.2681 10.4333 2.4192 3.3373
⏷ Show the Full List of 151 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 0.2818 4.7608 -0.2884 26.7766
TE8 CTRP2 0.4423 3.9144 0.1404 24.7729
OE21 CTRP2 -0.6133 3.727 -0.9628 31.914
TE-9 CTRP2 -0.3876 1.4787 -0.3972 29.2925
TE-4 CTRP2 -0.2418 1.3242 -0.2455 28.3008
TE-14 CTRP2 -0.2404 2.7749 -0.3599 28.6824
KYSE-180 CTRP2 -0.0022 2.8096 -0.1098 27.0551
TE-11 CTRP2 0.0621 2.8877 -0.0529 26.6518
TE-5 CTRP2 0.069 3.3802 -0.138 26.9229
EC-GI-10 CTRP2 0.3205 5.431 -0.4806 27.3191
KYSE-410 CTRP2 1.1077 5.3743 0.3849 21.8964
TE-10 CTRP2 1.8433 5.4483 1.1379 16.9815
OE19 CTRP2 2.3442 8.946 0.0406 19.926
KYSE-510 CTRP2 3.0651 7.0347 1.6472 11.8626
KYSE-70 CTRP2 3.1337 6.8064 1.8226 10.9831
KYSE-150 CTRP2 3.5422 9.0556 1.0813 13.144
KYSE-520 CTRP2 4.3032 11.5935 0.4529 14.1304
KYSE-140 CTRP2 4.6293 10.6761 1.1709 10.6797
OE33 CTRP2 4.8933 12.6173 0.4113 13.2059
KYSE-30 CTRP2 4.985 11.1327 1.2176 9.8751
COLO 680N CTRP2 5.5748 8.6428 2.8227 2.6114
KYSE-450 CTRP2 5.586 13.4279 0.5336 11.5647
TE-1 CTRP2 6.1846 10.719 2.2395 4.0956
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 1.2964 4.9898 0.7303 20.0687
MIA PaCa-2 CTRP2 -0.7224 1.6992 -0.7524 31.5932
PSN1 CTRP2 0.0324 3.5565 -0.2174 27.3141
BxPC-3 CTRP2 0.5096 3.6484 0.2807 24.0679
KP-4 CTRP2 1.0466 4.9851 0.4628 21.7861
PaTu 8988t CTRP2 1.2604 4.9607 0.7021 20.2776
HuP-T4 CTRP2 1.6487 4.447 1.2993 16.9249
Panc 08.13 CTRP2 1.8287 7.9584 0.0113 21.3237
L3.3 CTRP2 2.0739 5.993 1.1493 16.3155
Panc 03.27 CTRP2 2.1259 6.8496 0.8191 17.476
KP-3 CTRP2 2.3357 7.0596 0.9308 16.5067
Capan-1 CTRP2 2.7371 9.4077 0.1829 18.4613
Panc 10.05 CTRP2 2.7555 8.6349 0.5783 16.8927
KP-2 CTRP2 2.7582 6.8709 1.4328 13.4596
AsPC-1 CTRP2 3.2146 8.7904 0.9224 14.4888
DAN-G CTRP2 3.4174 14.4077 -1.697 23.3015
YAPC CTRP2 3.4391 6.7471 2.135 9.002
SW1990 CTRP2 3.5995 8.5217 1.3973 11.7281
SU.86.86 CTRP2 3.7223 7.8677 1.8301 9.6762
Hs 766T CTRP2 4.1286 9.0992 1.5567 10.0159
HuP-T3 CTRP2 4.4271 10.9042 0.8971 12.149
PaTu 8988s CTRP2 4.5006 15.4904 -1.3335 20.0203
SNU-213 CTRP2 4.9842 11.547 1.0121 10.6998
Panc 04.03 CTRP2 5.0324 11.4273 1.1077 10.2364
QGP-1 CTRP2 5.1537 10.476 1.6659 7.7835
SUIT-2 CTRP2 5.1809 8.2118 2.7782 3.2569
PK-59 CTRP2 5.4686 9.1929 2.5017 3.9666
HPAC CTRP2 5.7633 8.8311 2.8475 2.3191
SNU-410 CTRP2 6.0031 8.4547 3.1376 1.1432
CFPAC-1 CTRP2 6.0129 9.1576 2.8425 2.0917
TCC-Pan2 CTRP2 6.0532 7.4428 3.5494 0.161
Panc 02.03 CTRP2 6.0601 13.2177 0.9746 9.1419
Panc 05.04 CTRP2 6.3777 12.0795 1.7281 5.8018
PK-45H CTRP2 6.3834 11.8966 1.8172 5.4551
Capan-2 CTRP2 7.0691 15.554 0.537 9.3604
PaTu 8902 CTRP2 10.3414 23.7206 -1.2103 11.0719
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.5539 12.9074 0.7656 12.1914
RPMI-7951 CTRP2 -0.8827 2.6198 -1.0252 33.0295
CJM [Human melanoma] CTRP2 -0.5393 2.0707 -0.5902 30.4424
IGR-37 CTRP2 -0.4806 0.3555 -0.4806 29.8808
RVH-421 CTRP2 -0.4308 3.4764 -0.7032 30.4606
HMCB CTRP2 -0.2319 2.2978 -0.2888 28.4133
A2058 CTRP2 -0.2269 0.3318 -0.2269 28.1891
G-361 CTRP2 0.2657 3.1654 0.1185 25.4065
LOX-IMVI CTRP2 0.3439 2.8632 0.2531 24.6907
SK-MEL-5 CTRP2; CTRP1 0.4974 4.9561 -0.1205 25.5284
Hs 294T CTRP2 0.6947 4.831 0.1359 24.0187
WM88 CTRP2 1.0661 5.3319 0.3564 22.1215
IGR-39 CTRP2 1.14 6.6702 -0.1082 23.6113
Mel JuSo CTRP2 1.2152 5.8686 0.3049 21.8863
COLO 741 CTRP2 1.2348 7.0776 -0.1872 23.6313
MDA-MB-435S CTRP2 1.2506 3.9996 0.9996 19.2141
A-375 CTRP2; CTRP1 1.288 5.3281 0.5952 20.5969
Mel Ho CTRP2 1.3346 4.5711 0.9173 19.2628
Hs 944.T CTRP2 1.5505 4.8735 1.0461 18.1544
Hs 936.T CTRP2 1.7167 5.625 0.9325 18.1188
WM1799 CTRP2 1.7225 4.4979 1.3627 16.4732
MeWo CTRP2 1.7929 5.431 1.0916 17.2985
Hs 852.T CTRP2 1.8218 5.4641 1.1088 17.1526
IGR-1 CTRP2 1.9186 5.5441 1.178 16.6209
Hs 934.T CTRP2 1.9466 8.481 -0.1188 21.4995
WM983B CTRP2 2.0762 5.9184 1.184 16.1733
HT-144 CTRP2 2.3536 6.7856 1.0758 15.8864
K029AX CTRP2 2.4028 8.3184 0.3988 18.4263
COLO 829 CTRP2 2.5051 13.3746 -1.9848 26.1408
COLO 800 CTRP2 2.8506 13.1911 -1.5854 24.207
SK-MEL-3 CTRP2 3.59 9.2682 1.0169 13.3064
WM793 CTRP2 3.7996 8.0106 1.8253 9.5391
SK-MEL-2 CTRP2 4.3818 7.813 2.4016 6.0227
A101D CTRP2 4.7198 9.9851 1.5841 8.8339
WM266-4 CTRP2 4.7571 12.6919 0.2678 13.9956
WM115 CTRP2 5.0205 13.0191 0.3101 13.366
SK-MEL-1 CTRP2; CTRP1 5.0289 11.1923 1.2212 9.7869
Hs 839.T CTRP2 5.2957 10.2956 1.8557 6.7936
SK-MEL-30 CTRP2 5.4647 9.0799 2.5524 3.7738
SK-MEL-28 CTRP2; CTRP1 5.4844 6.2675 3.7502 0.0366
IPC-298 CTRP2 5.5755 9.2701 2.5336 3.7069
Hs 940.T CTRP2 5.6167 7.6252 3.2916 0.9601
COLO 792 CTRP2 5.6825 15.7423 -0.5347 15.2771
Hs 688(A).T CTRP2 5.7902 11.4909 1.621 7.0071
SK-MEL-31 CTRP2 5.8794 11.4777 1.6877 6.6187
WT2-iPS CTRP2 5.8806 15.606 -0.32 14.2057
UACC-62 CTRP2 6.9098 15.5017 0.4561 9.8714
Hs 895.T CTRP2 7.5546 18.8873 -0.7301 13.0618
UACC-257 CTRP2 7.5845 15.682 0.8074 7.7233
SK-MEL-24 CTRP2 7.8522 14.8824 1.335 5.5394
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 0.7451 6.6828 -0.5246 26.2008
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 CTRP2 -2.2581 0.0006 -2.2628 41.7489
IMR-32 CTRP2 -2.1841 -0.546 -2.1845 41.2424
MHH-NB-11 CTRP2 -1.5662 -0.7507 -1.5662 37.1203
SiMa CTRP2 -1.2288 2.3979 -1.3622 35.2948
SK-N-SH CTRP2 -1.0402 3.3097 -1.3286 34.5231
SK-N-FI CTRP2 -0.9957 0.8301 -0.9997 33.3293
SK-N-DZ CTRP2 -0.9393 3.8122 -1.3403 34.2013
CHP-126 CTRP2 -0.5703 2.0816 -0.6239 30.6583
Kelly CTRP2 -0.503 0.0633 -0.503 30.0304
NB1 CTRP2 -0.2949 0.3508 -0.2949 28.6426
KP-N-SI9s CTRP2 -0.2427 0.9213 -0.243 28.2952
NH-6 CTRP2 -0.2102 4.1925 -0.6487 29.5583
SK-N-BE(2) CTRP2 -0.0401 3.9079 -0.3843 28.1188
SK-N-AS CTRP2 0.9845 8.7751 -1.2052 27.7286
KP-N-YN CTRP2 3.8439 12.2405 -0.2511 17.6715
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 -0.167 2.5021 -0.2433 28.0467
HuCC-T1 CTRP2 1.9311 8.7528 -0.2628 22.0595
SNU-308 CTRP2 2.0842 7.2977 0.5713 18.5483
SNU-1079 CTRP2 2.9185 8.8067 0.645 16.2561
SNU-869 CTRP2 3.2862 9.5892 0.5904 15.6566
SNU-1196 CTRP2 3.6998 9.3415 1.0751 12.8437
HuH-28 CTRP2 5.6816 7.2733 3.4632 0.4523
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-ES-1 CTRP2 -1.1455 0.1131 -1.1457 34.3155
A-673 CTRP2 -0.6664 0.0754 -0.6664 31.1199
MHH-ES-1 CTRP2 -0.644 0.2761 -0.644 30.9706
TC71 CTRP2 -0.6081 1.1601 -0.6133 30.7482
SK-N-MC CTRP2 -0.6045 0.1551 -0.6045 30.7074
SaOS-2 CTRP2 -0.3093 0.8949 -0.3097 28.7398
HOS CTRP2 -0.0623 2.8216 -0.1761 27.4767
SW1353 CTRP2 0.3516 3.1093 0.2215 24.7749
SJSA-1 CTRP2 0.9483 3.4815 0.7955 20.8779
G-292 clone A141B1 CTRP2 1.0082 4.4136 0.6133 21.3478
MG-63 CTRP2 2.0852 7.0565 0.6836 18.1095
Hs 888.T CTRP2 4.0502 8.5605 1.7614 9.3137
Hs 822.T CTRP2 4.778 9.9364 1.6526 8.453
CAL-78 CTRP2 5.31 12.8748 0.6014 11.7593
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 -1.3779 0.5942 -1.3824 35.8798
CAL-148 CTRP2 -1.2372 -0.0616 -1.2373 34.9268
AU565 CTRP2 -0.6672 5.6214 -1.613 34.0281
HMC-1-8 CTRP2 -0.3827 0.9742 -0.3837 29.2311
HCC1500 CTRP2 -0.231 8.095 -2.1396 33.9394
SK-BR-3 CTRP2 0.0662 3.227 -0.1094 26.8334
CAL-51 CTRP2 0.1066 2.9008 -0.0072 26.3514
Hs 578T CTRP2 0.1563 3.9245 -0.1744 26.7719
HCC1395 CTRP2 0.6969 4.0316 0.3865 23.1114
MDA-MB-157 CTRP2 0.7743 3.8242 0.5261 22.3745
MCF-7 CTRP2; CTRP1 1.1344 7.166 -0.3289 24.4132
JIMT-1 CTRP2 1.1379 5.0552 0.536 21.2496
HCC38 CTRP2 1.158 4.8274 0.6387 20.8111
MDA-MB-468 CTRP2 1.9495 5.6895 1.1499 16.6453
CAL-85-1 CTRP2 2.1609 8.106 0.2672 19.5235
MDA-MB-453 CTRP2 2.7628 8.9473 0.4324 17.4449
UACC-812 CTRP2 2.8235 8.9021 0.5106 17.0009
MDA-MB-361 CTRP2 2.9745 11.8032 -0.786 21.395
BT-20 CTRP2 3.1833 9.1444 0.7191 15.3713
HCC202 CTRP2 3.5228 8.6013 1.2905 12.3286
BT-549 CTRP2 3.7131 10.3103 0.6027 14.7098
HCC2218 CTRP2 3.9309 7.2916 2.2963 7.3025
CAL-120 CTRP2 4.1929 5.4362 3.4357 2.0268
HDQ-P1 CTRP2 4.2003 9.3909 1.4696 10.2411
CAMA-1 CTRP2 4.2878 16.9383 -2.2309 23.0565
ZR-75-1 CTRP2 4.5432 9.6722 1.6029 9.0643
ZR-75-30 CTRP2 5.0065 10.3202 1.6344 8.1483
BT-474 CTRP2 5.0367 10.4262 1.6046 8.2206
KPL-1 CTRP2 5.073 5.911 3.7244 0.1482
MDA-MB-231 CTRP2 5.3534 8.9319 2.5502 3.9269
HCC1143 CTRP2 5.7703 8.3517 3.0622 1.5684
HCC1419 CTRP2 6.1504 7.6434 3.5148 0.1874
HCC1937 CTRP2 6.5344 8.3653 3.4028 0.2593
T-47D CTRP2 6.7655 14.5303 0.8229 8.72
HCC1428 CTRP2 6.84 16.0993 0.1224 11.1709
BT 245 CTRP2 0.2763 3.7344 0.0055 25.7667
BT 145 CTRP2 0.4993 3.4522 0.314 23.9833
BT 231 CTRP2 0.7512 5.2957 0.0321 24.2241
BT 239 CTRP2 1.188 5.1628 0.5503 21.0515
BT164 CTRP2 1.7163 6.0274 0.7644 18.7651
BT 416 CTRP2 1.7997 5.1961 1.1919 16.8957
BT 112 CTRP2 1.8917 7.2967 0.38 19.7763
BT 359 CTRP2 2.2042 11.2475 -1.211 24.5723
BT 286 CTRP2 2.5877 6.2819 1.5412 13.4391
BT 271 CTRP2 2.6001 8.4634 0.5161 17.4997
BT 179 CTRP2 2.7418 8.4712 0.6453 16.661
BT 504 CTRP2 2.9766 8.0657 1.062 14.4556
BT147 CTRP2 3.0933 17.7184 -3.6287 28.8466
BT 172 CTRP2 3.1377 9.6187 0.4433 16.5566
BT 422 CTRP2 3.7886 9.0393 1.3021 11.7344
BT 428 CTRP2 3.9962 10.6947 0.6495 13.9567
BT 232 CTRP2 4.1436 9.5293 1.3541 10.8249
BT 248 CTRP2 4.1579 11.3372 0.4621 14.3739
BT 224 CTRP2 4.1982 9.8249 1.2511 11.1441
BT 228 CTRP2 4.3303 11.721 0.4112 14.24
BT 330 CTRP2 4.4871 15.0418 -1.1204 19.3708
BT 333 CTRP2 4.5653 9.9871 1.4635 9.5992
BT 320 CTRP2 4.5704 6.3876 3.2416 2.2426
BT 159 CTRP2 4.893 11.3926 1.0189 10.8289
BT 328 CTRP2 5.1656 11.2717 1.2839 9.309
BT 444 CTRP2 5.3203 11.347 1.3603 8.7537
BT 482 CTRP2 5.4281 10.9716 1.6207 7.5407
BT 216 CTRP2 5.8551 7.5125 3.4456 0.4127
BT 139 CTRP2 5.8662 11.3551 1.7374 6.4412
BT 340 CTRP2 6.1797 14.2498 0.5584 10.5455
BT 131 CTRP2 6.6343 18.1046 -0.9956 15.2751
BT 440 CTRP2 6.7128 12.559 1.7145 5.4429
BT 187 CTRP2 6.8835 14.3176 1.0008 7.9004
BT 498 CTRP2 8.749 26.8382 -3.7442 19.6979
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -1.2484 -0.7904 -1.2484 35.0009
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-60 CTRP2 -0.5074 0.4905 -0.5074 30.0593
Daoy CTRP2 -0.4758 1.1683 -0.4796 29.8615
AM-38 CTRP2 -0.4326 2.2947 -0.5005 29.7883
LN-18 CTRP2 -0.1048 5.1817 -0.8502 29.879
DK-MG CTRP2 -0.0007 2.9142 -0.1248 27.1015
YH-13 CTRP2 0.2312 3.4702 0.0186 25.8634
Hs 683 CTRP2 0.2473 4.6212 -0.2805 26.8557
SF539 CTRP2 0.4217 3.7823 0.1522 24.7957
Becker CTRP2 0.4727 4.1248 0.1158 24.7662
D283 Med CTRP2 0.6211 5.9799 -0.3685 26.0277
A-172 CTRP2 0.6868 3.2698 0.5542 22.5497
TM-31 CTRP2 0.9605 5.395 0.2195 22.9305
LN-229 CTRP2; CTRP1 1.5971 6.0773 0.6191 19.6447
GaMG CTRP2 1.6248 4.569 1.2328 17.2418
YKG-1 CTRP2 1.7789 6.0769 0.8082 18.4278
KALS-1 CTRP2 1.7937 7.0635 0.3878 20.0018
SF268 CTRP2 2.0681 7.5074 0.4578 19.0273
SNU-466 CTRP2 2.3011 6.1206 1.3257 15.0273
ONS-76 CTRP2 2.6313 7.8428 0.8457 16.1265
U-118MG CTRP2 2.665 11.1622 -0.7466 21.9673
M059K CTRP2 2.8687 10.4616 -0.2161 19.6403
SF126 CTRP2 3.2339 7.6572 1.4994 12.0903
42-MG-BA CTRP2 3.3186 9.3451 0.7403 14.993
SNU-1105 CTRP2 3.3319 8.6382 1.103 14.4287
SNU-489 CTRP2 3.3686 10.4858 0.217 16.9263
U-251MG CTRP2 3.5047 10.1349 0.5106 15.5038
NMC-G1 CTRP2 3.5738 15.1853 -1.9517 23.7086
SNU-738 CTRP2 3.7937 11.2718 0.1908 16.1386
GB-1 CTRP2 3.818 8.4633 1.6149 10.38
KG-1-C CTRP2 3.875 12.1744 -0.1918 17.3938
GOS-3 CTRP2 3.9619 12.1192 -0.0914 16.8519
SW1088 CTRP2 4.1836 10.0166 1.1434 11.6115
KNS-42 CTRP2 4.3299 10.0546 1.243 10.9301
CAS-1 CTRP2 4.3448 10.8778 0.844 12.5145
U-87MG ATCC CTRP2 4.7911 10.578 1.3448 9.6902
DBTRG-05MG CTRP2 5.0623 9.7866 1.9371 6.8221
SF295 CTRP2 5.3253 11.1302 1.47 8.3053
SNU-626 CTRP2 5.3328 12.6095 0.7493 11.1496
T98G CTRP2 5.4841 10.2407 2.0131 5.8832
SNB-75 CTRP2 5.5059 14.5483 -0.0777 13.9653
GMS-10 CTRP2 5.55 14.4802 -0.0111 13.6501
SW1783 CTRP2 5.5607 11.967 1.2304 8.8954
KNS-81 CTRP2 5.6087 9.8168 2.2982 4.5816
SNU-201 CTRP2 5.7041 7.2376 3.4865 0.3883
8-MG-BA CTRP2 6.8177 14.1457 1.0393 7.8431
CCF-STTG1 CTRP2 7.2811 15.6044 0.6513 8.6664
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 -2.4099 -0.0835 -2.4149 42.7618
HEC-151 CTRP2; CTRP1 -1.6823 2.2393 -1.8244 38.3136
RL95-2 CTRP2 -1.2658 -0.1201 -1.2658 35.1173
JHUEM-1 CTRP2 -0.5726 2.08 -0.6261 30.6734
HEC-265 CTRP2 -0.1964 1.9122 -0.2203 28.0655
JHUEM-7 CTRP2 0.0761 4.5311 -0.4382 27.9343
MFE-319 CTRP2 0.4746 3.8375 0.1958 24.4769
HEC-50B CTRP2 0.8635 10.809 -2.2744 31.0369
AN3-CA CTRP2 1.1289 6.2071 0.0754 22.976
MFE-296 CTRP2 1.2097 5.2052 0.5578 20.9609
HEC-108 CTRP2 1.3616 5.4246 0.6365 20.2331
ESS-1 CTRP2 1.3693 5.4924 0.6182 20.2804
HEC-251 CTRP2 1.5385 4.6966 1.0957 18.0035
JHUEM-3 CTRP2 1.8487 7.881 0.0671 21.0654
HEC-59 CTRP2 1.9167 5.8707 1.0392 17.1632
HEC-1-A CTRP2 2.6923 8.0865 0.7857 16.2208
HEC-6 CTRP2 3.4202 7.9525 1.522 11.591
KLE CTRP2 3.5994 8.573 1.3716 11.8347
EFE-184 CTRP2 4.7126 9.4183 1.8593 7.7115
HEC-1-B CTRP2 7.909 17.8076 0.0188 10.0843
EN CTRP2 8.7758 20.8234 -0.8425 11.8044
Ishikawa (Heraklio) 02 ER- CTRP2 -0.791 0.1807 -0.791 31.951
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 0.0247 6.7486 -1.3077 30.8842
TUHR4TKB CTRP2 0.4339 4.6933 -0.101 25.6526
KMRC-3 CTRP2 0.4499 4.2457 0.0559 25.0484
BFTC-909 CTRP2 1.1696 5.3442 0.4625 21.4308
786-O CTRP2 1.3923 3.9378 1.1709 18.1639
CAL-54 CTRP2 1.4185 6.5353 0.2382 21.57
KMRC-1 CTRP2 1.9799 8.0318 0.1256 20.5117
ACHN CTRP2 3.1205 8.534 0.964 14.5284
Caki-2 CTRP2 3.5406 8.883 1.1658 12.8027
VMRC-RCW CTRP2 3.8754 7.3339 2.2281 7.6991
VMRC-RCZ CTRP2 4.815 12.8695 0.2248 14.0531
Caki-1 CTRP2 4.9188 9.6079 1.92 7.1204
A-498 CTRP2 5.0218 10.3548 1.6288 8.1463
SNU-1272 CTRP2 5.1483 9.8182 1.9835 6.4995
TUHR10TKB CTRP2 5.2065 8.5786 2.6213 3.8419
RCC10RGB CTRP2; CTRP1 5.2141 13.8652 0.0391 14.0383
OS-RC-2 CTRP2 5.4709 9.1364 2.5298 3.8541
KMRC-20 CTRP2 5.6648 12.116 1.2318 8.7304
TUHR14TKB CTRP2 6.0373 8.2522 3.2366 1.7752
KMRC-2 CTRP2 8.744 17.843 0.5185 7.3922
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 CTRP1 -1.9795 3.334 -2.3565 70.7991
CL-34 CTRP1 -1.8197 4.0987 -2.3785 68.1787
SW48 CTRP2 -1.3526 -0.042 -1.3528 35.6966
T84 CTRP2 -1.3525 2.3787 -1.4919 36.1311
SNU-175 CTRP2; CTRP1 -1.3287 1.5374 -1.3719 35.6768
LS513 CTRP2 -1.3093 0.1118 -1.3097 35.4087
CCK-81 CTRP2 -0.9055 1.3931 -0.9245 32.7777
RKO CTRP2; CTRP1 -0.7192 1.9727 -0.7701 31.6416
HCT 15 CTRP2 -0.7161 0.6744 -0.7169 31.4539
LS180 CTRP2; CTRP1 -0.6466 2.9967 -0.8365 31.6179
KM12 CTRP2; CTRP1 -0.617 5.3782 -1.4725 33.4645
LoVo CTRP2; CTRP1 -0.5702 3.0856 -0.7709 31.1466
GP2d CTRP2 -0.3686 2.4819 -0.4551 29.4248
SW948 CTRP2; CTRP1 -0.2647 5.5661 -1.1594 56.0333
HCC-56 CTRP2 -0.2614 1.8097 -0.2817 28.4872
SNU-C5 CTRP2; CTRP1 -0.2252 3.704 -0.5337 29.2215
NCI-H508 CTRP2; CTRP1 0.0194 2.9271 -0.1053 26.9698
SNU-C4 CTRP2; CTRP1 0.0828 4.523 -0.4284 27.8794
SNU-1040 CTRP1 0.261 7.5352 -1.3897 51.6528
SNU-407 CTRP2 0.4687 2.5479 0.4244 23.6993
SNU-C1 CTRP2 0.6505 4.7433 0.1176 24.217
MDST8 CTRP2; CTRP1 0.6565 3.9869 0.3547 23.3491
COLO 320 CTRP2; CTRP1 0.8996 8.2072 -1.0319 27.427
CW-2 CTRP2; CTRP1 0.964 5.2057 0.2939 22.648
COLO205 CTRP2 0.9677 4.0133 0.6871 21.2033
HT115 CTRP2; CTRP1 1.0196 4.8689 0.4746 21.8219
SNU-61 CTRP2; CTRP1 1.151 5.1013 0.5332 21.2221
NCI-H716 CTRP2 1.1844 4.9985 0.6066 20.8528
CL-40 CTRP1 1.3475 6.8435 0.0311 42.7298
HCT 116 CTRP2; CTRP1 1.3598 7.2742 -0.1465 23.1422
LS1034 CTRP2 1.8137 7.5191 0.1999 20.6602
CL-11 CTRP2 2.6498 7.3054 1.1211 14.9796
NCI-H747 CTRP2 2.7601 8.9936 0.4072 17.5488
LS123 CTRP2; CTRP1 2.8022 7.7317 1.0614 14.8594
DLD-1 CTRP2 2.8363 9.4216 0.2673 17.912
SK-CO-1 CTRP2 2.9151 7.8324 1.1186 14.3672
HCT 8 CTRP2; CTRP1 2.9729 8.7388 0.7283 15.8032
HT-55 CTRP2; CTRP1 3.0662 10.4355 -0.0256 18.4978
C2BBe1 CTRP2 3.0901 11.9028 -0.7331 20.9595
SNU-1033 CTRP2 3.1601 13.7364 -1.5847 23.5207
COLO201 CTRP2 3.4292 7.5195 1.7445 10.6486
SW1417 CTRP2 3.5162 10.1612 0.5075 15.4917
SNU-503 CTRP2 3.6702 12.5259 -0.5408 19.0553
SW620 CTRP2; CTRP1 5.4668 12.6256 0.8402 10.5772
LS411N CTRP2 5.7821 7.1486 3.5515 0.2297
SW480 CTRP1 6.2394 20.1956 -2.3156 29.2613
OUMS-23 CTRP2 6.2626 13.4443 1.0045 8.7339
HT-29 CTRP2; CTRP1 6.3023 13.0002 1.2438 7.7608
COLO 678 CTRP2; CTRP1 7.0557 16.7806 -0.0579 11.4991
RCM-1 [Human ESC] CTRP2; CTRP1 7.6013 16.5564 0.4094 9.1198
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-878 CTRP2 -1.2824 1.2368 -1.3051 35.3022
SNU-182 CTRP2 -0.0379 3.3096 -0.2392 27.6145
HLF CTRP2 -0.0324 2.0367 -0.0581 26.978
JHH-4 CTRP2 -0.0304 2.0922 -0.0597 26.9766
HuH-1 CTRP2 0.5186 4.9582 -0.0983 25.3858
Li-7 CTRP2 1.0469 5.3815 0.3171 22.3218
JHH-5 CTRP2 1.1523 5.0437 0.5556 21.1351
SNU-423 CTRP2 1.2038 4.4636 0.8103 20.0437
SNU-398 CTRP2; CTRP1 1.2534 5.4495 0.5115 21.0085
SNU-886 CTRP2 1.3061 5.1084 0.6973 20.1637
JHH-1 CTRP2 1.3062 4.1097 1.0295 18.9369
JHH-2 CTRP2 1.3328 4.9004 0.8017 19.6972
HuH-6 CTRP2 1.8394 6.8345 0.5373 19.3106
PLC/PRF/5 CTRP2 2.5564 6.6356 1.3463 14.3
SNU-449 CTRP2 3.0563 7.8066 1.2625 13.4596
SK-HEP-1 CTRP2 3.585 10.3601 0.4678 15.5028
SNU-387 CTRP2 4.0415 11.2451 0.4119 14.7956
SNU-475 CTRP2 4.3673 10.2343 1.1834 11.1039
JHH-6 CTRP2 5.2261 11.2924 1.3183 9.0727
Hep-G2 CTRP2; CTRP1 5.795 9.8753 2.3895 3.9908
Hep 3B2.1-7 CTRP2 6.1264 13.2906 0.9852 9.004
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 151 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1876 CTRP1 -2.8258 7.0808 -4.4701 66.9085
NCI-H1963 CTRP1 -2.126 3.9477 -2.6713 69.9801
NCI-H596 CTRP1 -1.8584 3.2961 -2.2159 70.2844
COLO 699 CTRP1 -1.5903 14.2258 -6.2856 57.0732
SHP-77 CTRP2 -1.4886 -0.9372 -1.4886 36.6032
NCI-H526 CTRP2 -1.3675 -0.7357 -1.3675 35.7957
NCI-H1155 CTRP2 -1.3565 0.1554 -1.357 35.7237
NCI-H446 CTRP2 -1.2583 1.0361 -1.2717 35.1114
NCI-H524 CTRP2 -1.1707 2.1974 -1.2723 34.8107
NCI-H841 CTRP2; CTRP1 -1.156 2.064 -1.2404 34.6584
DV-90 CTRP2 -1.0607 2.0864 -1.142 34.015
NCI-H1703 CTRP2 -0.8488 0.4466 -0.8491 32.3373
NCI-H1836 CTRP1 -0.8174 4.329 -1.3507 61.7353
SCLC-21H CTRP1 -0.7594 1.6771 -0.7893 66.2345
NCI-H2122 CTRP2; CTRP1 -0.7503 2.0211 -0.8073 31.8691
NCI-H23 CTRP2 -0.6912 1.818 -0.7281 31.4085
NCI-H522 CTRP2 -0.6674 2.4507 -0.7695 31.4664
HARA [Human squamous cell lung carcinoma] CTRP2 -0.6567 1.7686 -0.6887 31.1622
SBC-5 CTRP2 -0.6016 0.1663 -0.6016 30.6879
RERF-LC-A1 CTRP2 -0.5963 0.4514 -0.5963 30.6524
NCI-H1341 CTRP2 -0.5731 0.8577 -0.5743 30.5016
HCC1438 CTRP2 -0.5411 2.2905 -0.6149 30.5311
LK2 CTRP2 -0.5346 -0.1995 -0.5346 30.2408
MOR/CPR CTRP2 -0.5028 0.3041 -0.5028 30.0288
NCI-H211 CTRP2 -0.4019 1.351 -0.4083 29.3774
HCC44 CTRP2 -0.3751 2.238 -0.4336 29.3736
DMS 114 CTRP2 -0.3136 2.7202 -0.43 29.1594
RERF-LC-MS CTRP2 -0.3056 1.6099 -0.318 28.7553
LCLC-97TM1 CTRP2 -0.1953 5.1601 -0.9406 30.46
DMS 273 CTRP2 -0.1938 3.001 -0.3479 28.4896
NCI-H1339 CTRP2 -0.1838 2.7373 -0.2934 28.2719
NCI-H520 CTRP2 -0.0717 3.3527 -0.285 27.8801
Lu-99 CTRP2 -0.0503 2.4648 -0.115 27.2293
NCI-H1781 CTRP1 -0.0223 4.7584 -0.6179 54.9589
HCC1359 CTRP1 -0.0179 4.4356 -0.5111 55.1497
DMS 454 CTRP2 0.01 5.5365 -0.8531 29.5228
NCI-H2081 CTRP2; CTRP1 0.0409 4.3102 -0.4092 27.9463
HCC1588 CTRP2 0.2 2.7307 0.118 25.6195
NCI-H1694 CTRP2; CTRP1 0.278 4.9724 -0.3636 27.0486
NCI-H322 CTRP2 0.2857 3.8368 -0.0101 25.7918
COLO 668 CTRP2 0.3038 3.3323 0.1269 25.256
HCC4006 CTRP2; CTRP1 0.4118 5.2762 -0.326 26.5085
COR-L23 CTRP1 0.4286 7.668 -1.2739 50.4959
Lu-65 CTRP2 0.4833 3.0021 0.3813 23.7997
NCI-H1734 CTRP2 0.5036 3.7456 0.2506 24.193
HCC2279 CTRP2 0.5325 3.6095 0.3148 23.876
NCI-H2141 CTRP2; CTRP1 0.5492 7.7902 -1.2032 28.9723
NCI-H69 CTRP2 0.5561 4.3258 0.1478 24.3956
NCI-H1792 CTRP2 0.5897 3.6816 0.3601 23.5376
NCI-H1568 CTRP2 0.5922 5.0288 -0.0433 24.9682
COR-L51 CTRP2; CTRP1 0.6007 5.8335 -0.3328 25.9642
NCI-H2073 CTRP1 0.643 24.0254 -8.9316 49.6671
PC-14 CTRP2 0.7641 4.2704 0.3912 22.889
NCI-H889 CTRP2 0.8017 4.4379 0.3809 22.8124
NCI-H2196 CTRP2 0.8872 8.7679 -1.2992 28.2882
NCI-H146 CTRP2 0.9232 4.4438 0.5113 21.9741
NCI-H1944 CTRP2 0.9765 9.4063 -1.505 28.6482
Calu-6 CTRP2 1.0433 4.0511 0.7592 20.7131
SK-MES-1 CTRP2 1.0435 6.0865 0.0353 23.3643
VMRC-LCD CTRP2 1.0488 4.1328 0.7421 20.758
NCI-H2029 CTRP2 1.0496 5.6052 0.234 22.6199
HCC366 CTRP2 1.1455 5.2067 0.4884 21.4039
NCI-H1693 CTRP2 1.2278 4.5387 0.812 19.9663
NCI-H661 CTRP2 1.2348 6.3294 0.1351 22.4597
LUDLU-1 CTRP2 1.2383 6.4718 0.0785 22.658
NCI-H1581 CTRP2 1.2532 5.0942 0.6457 20.5087
NCI-H1385 CTRP2 1.258 7.9994 -0.5764 24.93
DMS 53 CTRP2 1.2814 5.7248 0.4328 21.2232
NCI-H2110 CTRP2; CTRP1 1.3266 5.6336 0.517 20.7809
NCI-H838 CTRP2 1.3695 4.4271 1.0022 18.8468
NCI-H1105 CTRP2; CTRP1 1.3803 7.2201 -0.1016 22.9242
NCI-H1184 CTRP2 1.3891 5.2521 0.7322 19.7954
NCI-H2009 CTRP2 1.394 5.0591 0.8099 19.4898
NCI-H358 CTRP2 1.4169 5.2753 0.7531 19.6376
EBC-1 CTRP2 1.5373 5.7903 0.6761 19.5919
CAL-12T CTRP2; CTRP1 1.5472 6.6691 0.3125 20.9419
HCC78 CTRP2 1.7536 6.5453 0.5785 19.3789
NCI-H2087 CTRP2 1.7637 6.0926 0.7857 18.5552
HCC2108 CTRP2; CTRP1 1.9311 6.8464 0.6246 18.7349
HCC827 CTRP2; CTRP1 1.9854 7.8291 0.2262 20.12
NCI-H1355 CTRP2 1.9885 5.3895 1.3148 15.9012
NCI-H810 CTRP2 2.0515 6.6849 0.8192 17.6665
HCC95 CTRP2 2.0622 8.4139 0.0253 20.6782
NCI-H2170 CTRP2 2.309 6.056 1.3626 14.8605
NCI-H1623 CTRP2 2.3432 9.2979 -0.1307 20.5609
NCI-H1395 CTRP2 2.3738 8.8328 0.1233 19.5453
NCI-H1092 CTRP2 2.4275 8.9483 0.1183 19.4347
LOU-NH91 CTRP2 2.4754 6.0099 1.5521 13.6795
COR-L95 CTRP2 2.5364 5.9332 1.6484 13.1393
Calu-3 CTRP2 2.6595 9.1487 0.2379 18.4327
NCI-H1666 CTRP2 2.7736 6.5748 1.588 12.7925
NCI-H1869 CTRP2 2.8014 10.398 -0.2456 19.9009
NCI-H2286 CTRP2 2.9684 4.4449 2.7277 7.7536
Sq-1 CTRP2; CTRP1 2.9782 7.2833 1.4447 12.8931
NCI-H1373 CTRP2 3.0708 6.5292 1.8968 10.8237
HCC15 CTRP2; CTRP1 3.0712 8.1642 1.101 14.0839
NCI-H2405 CTRP2 3.1354 8.2994 1.0931 13.9726
NCI-H460 CTRP2; CTRP1 3.2076 9.2004 0.7131 15.3418
LCLC-103H CTRP2 3.2388 8.6006 1.0381 13.968
LC-1/sq-SF CTRP2 3.3216 8.622 1.1019 13.5289
NCI-H1915 CTRP2 3.3262 9.4835 0.6783 15.2226
NCI-H1838 CTRP2 3.3496 8.8819 0.9979 13.8908
COR-L88 CTRP2 3.3847 7.0819 1.9204 10.0141
NCI-H647 CTRP2 3.385 9.5276 0.7083 14.9775
NCI-H1755 CTRP2; CTRP1 3.4517 7.9362 1.5582 11.3737
NCI-H650 CTRP2 3.4616 13.0855 -0.9989 21.04
A-549 CTRP2 3.4676 8.3922 1.3459 12.2171
NCI-H1793 CTRP2 3.4874 10.9264 0.1009 17.1128
HCC1833 CTRP2; CTRP1 3.5534 10.1874 0.5267 15.3389
T3M-10 CTRP2; CTRP1 3.6079 10.0217 0.6564 14.7145
NCI-H2030 CTRP2; CTRP1 3.6868 9.2146 1.1273 12.6572
NCI-H1435 CTRP2 3.7327 7.8485 1.8487 9.5773
KNS-62 CTRP2 3.7351 7.5922 1.9786 9.0286
HCC2935 CTRP2; CTRP1 3.7749 11.3945 0.1135 16.4685
LXF 289 CTRP2 3.7975 7.732 1.9627 8.9688
NCI-H1299 CTRP2 3.8811 8.2814 1.7594 9.6519
HCC1171 CTRP2 4.0883 9.7389 1.2038 11.5475
NCI-H2342 CTRP2; CTRP1 4.1215 11.0493 0.576 14.0004
NCI-H196 CTRP2 4.1499 9.4169 1.4154 10.5599
NCI-H2106 CTRP2 4.165 10.2396 1.0166 12.1613
RERF-LC-Ad2 CTRP2 4.2439 10.0409 1.1803 11.3468
DMS 79 CTRP2 4.2551 8.1412 2.138 7.3533
ChaGo-K-1 CTRP2 4.2583 13.5351 -0.554 17.9187
NCI-H1650 CTRP2 4.2942 8.9807 1.7504 8.9012
EPLC-272H CTRP2 4.3693 14.2086 -0.7999 18.5433
NCI-H226 CTRP2 4.4612 9.4223 1.663 8.9617
NCI-H2228 CTRP2 4.4635 8.562 2.0929 7.1694
EKVX CTRP2 4.5119 12.9591 -0.0604 15.671
NCI-H2085 CTRP2 4.5568 11.0747 0.9153 11.8382
NCI-H1573 CTRP2 4.6043 10.1099 1.4329 9.656
NCI-H727 CTRP2 4.618 10.1051 1.4459 9.5784
SW1573 CTRP2 4.8237 9.0434 2.1275 6.4199
NCI-H2172 CTRP2; CTRP1 4.9197 9.1827 2.1295 6.2582
COR-L105 CTRP2 5.0949 11.5568 1.0907 10.1994
NCI-H2023 CTRP2; CTRP1 5.147 9.8443 1.9699 6.5569
RERF-LC-Ad1 CTRP2 5.2515 5.9148 3.7884 0.0316
BEN CTRP2 5.2923 6.3414 3.6534 0.2058
SW1271 CTRP2 5.3641 9.4114 2.3293 4.7879
SK-LU-1 CTRP2; CTRP1 5.6079 11.2785 1.598 7.3625
HCC1195 CTRP2; CTRP1 5.6087 11.26 1.6075 7.3236
NCI-H2126 CTRP2 5.6172 7.0979 3.503 0.3903
NCI-H292 CTRP2 5.6774 15.4672 -0.4027 14.8297
NCI-H441 CTRP2; CTRP1 5.7901 10.7506 1.9747 5.6113
IA-LM CTRP2 5.9406 13.6884 0.6624 10.516
NCI-H3255 CTRP1 6.0083 17.7124 -1.2629 26.8727
NCI-H2291 CTRP2 6.0898 8.3842 3.2079 0.8828
Calu-1 CTRP2 6.1485 14.0834 0.6172 10.3717
HOP-62 CTRP2 7.3148 17.767 -0.3553 12.1557
NCI-H1563 CTRP2 9.662 22.5185 -1.0735 11.4405
HOP-92 CTRP2 10.2158 46.3466 -12.2427 30.5651
Hs 888.Lu CTRP2 3.0778 9.3716 0.5116 16.4228
⏷ Show the Full List of 151 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 -0.984 -0.0399 -0.984 33.2377
SYO-1 CTRP2 0.0972 4.0467 -0.2721 27.297
P-STS CTRP2 1.2222 5.383 0.5039 21.1257
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.8118 7.8924 -0.9799 27.5123
A2780 CTRP2; CTRP1 -1.0675 1.04 -1.0772 33.8272
OVKATE CTRP1 -0.8648 4.8399 -1.5601 61.2864
TOV-112D CTRP2 -0.5782 2.0543 -0.6296 30.7037
OC 314 CTRP2 -0.4749 1.0506 -0.4771 29.8503
RMUG-S CTRP1 -0.4341 12.6238 -4.3981 53.8126
OVCAR-8 CTRP2; CTRP1 -0.3571 2.4751 -0.442 29.3428
OVK18 CTRP2; CTRP1 -0.0203 3.6588 -0.2992 27.7636
SNU-8 CTRP2 -0.011 2.777 -0.1142 27.0985
MCAS CTRP2 0.1144 3.2814 -0.0681 26.5362
ONCO-DG-1 CTRP2 0.5849 4.4279 0.148 24.3072
JHOM-1 CTRP2; CTRP1 1.041 7.2073 -0.4428 25.0725
OV-90 CTRP2; CTRP1 1.0637 6.6205 -0.1662 24.0338
OVCAR-4 CTRP2; CTRP1 1.2356 5.873 0.3247 21.7554
COV434 CTRP2; CTRP1 1.3583 7.482 -0.2411 23.4859
TYK-nu CTRP2; CTRP1 1.569 7.3139 0.0477 21.8704
RMG-I CTRP2; CTRP1 1.7965 6.4661 0.6574 18.9615
EFO-21 CTRP2 1.8011 5.9918 0.8676 18.1386
OAW42 CTRP2; CTRP1 1.8229 5.2636 1.19 16.8381
COV644 CTRP2; CTRP1 2.323 8.7352 0.1221 19.6729
IGROV-1 CTRP2; CTRP1 2.358 7.9861 0.5149 18.0856
TOV-21G CTRP2 2.3846 6.4075 1.2805 14.993
OV7 CTRP2; CTRP1 2.7182 9.9029 -0.0777 19.4793
COV362 CTRP2; CTRP1 2.7574 9.3923 0.2092 18.3144
JHOC-5 CTRP2; CTRP1 3.0432 10.5984 -0.127 18.9231
SNU-119 CTRP2 3.1175 7.8474 1.299 13.1727
OAW28 CTRP2 3.2604 9.1778 0.7715 14.9942
OV56 CTRP2 3.3202 7.5876 1.6123 11.4339
Caov-3 CTRP2; CTRP1 3.5198 8.0713 1.5515 11.2569
DOV13 CTRP2 4.2133 8.9772 1.6868 9.9629
SK-OV-3 CTRP2 4.342 8.9567 1.8006 8.6051
OVCAR-5 CTRP2 4.8043 11.9696 0.6641 12.3869
OVISE CTRP2 4.8848 9.3622 2.0158 7.2548
JHOS-2 CTRP2 5.0928 11.4878 1.1232 10.0732
OVSAHO CTRP2 5.3546 6.9867 3.4275 0.7414
HEY A8 CTRP2 5.4869 10.8525 1.7199 7.0543
OVTOKO CTRP2 5.6403 10.9766 1.766 6.6461
Kuramochi CTRP2 5.7719 10.1108 2.2649 4.5003
EFO-27 CTRP2; CTRP1 6.098 15.7139 -0.2138 13.4831
SNU-840 CTRP2; CTRP1 6.22 13.2012 1.0922 8.4584
FU-OV-1 CTRP2 6.5345 8.3896 3.3941 0.273
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 1.8511 9.2925 -0.5971 23.4354
Yamato-SS CTRP2 5.9811 16.5158 -0.6934 15.3207
Rh41 CTRP2 -1.4153 -0.2141 -1.4153 36.1143
HT-1080 CTRP2; CTRP1 -1.0069 1.3258 -1.0257 33.4531
SW982 CTRP2 -0.3403 2.5364 -0.4322 29.2544
TE 617.T CTRP2 -0.2666 3.1646 -0.4576 29.0992
RKN CTRP2; CTRP1 -0.0089 1.7077 -0.0181 26.7658
TTC-709 CTRP2 0.1298 6.6907 -1.1734 30.1516
KYM-1 CTRP2 0.1319 3.0478 -0.0047 26.2614
RD CTRP2 0.5133 3.8989 0.2219 24.2641
G-401 CTRP2 0.5215 3.4323 0.3424 23.8136
GCT CTRP2 0.6287 4.2337 0.2545 23.7926
MES-SA CTRP2 0.8401 4.333 0.4551 22.4282
G-402 CTRP2 1.0005 6.7655 -0.2936 24.6654
BT-16 CTRP2 1.2854 4.5002 0.8872 19.519
A-204 CTRP2 1.5386 6.11 0.5443 20.0894
BT-12 CTRP2 1.5585 4.1784 1.2847 17.2472
Tm87-16 CTRP2 1.6531 8.1262 -0.2405 22.6963
SK-LMS-1 CTRP2 1.7655 6.5722 0.5789 19.3459
SK-UT-1 CTRP2 1.7872 4.9844 1.2595 16.6736
TE 441.T CTRP2 2.214 8.1346 0.3051 19.2473
Hs 729.T CTRP2 2.8604 8.1033 0.9355 15.2314
Rh18 CTRP2 5.1659 8.7024 2.5351 4.2411
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 5.3465 9.9868 2.0409 5.9704
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP2 -1.4207 -0.5613 -1.4207 36.15
MSTO-211H CTRP2 0.6984 3.7481 0.4624 22.8364
MPP 89 CTRP2 0.9146 3.6465 0.7224 21.2414
JL-1 CTRP2 1.6628 4.686 1.2338 17.127
IST-Mes1 CTRP2 1.8287 6.0711 0.8623 18.0847
NCI-H2452 CTRP2 3.2044 6.8384 1.8733 10.6124
ACC-MESO-1 CTRP2 5.2809 8.1404 2.875 2.7559
NCI-H2052 CTRP2 5.9278 10.4104 2.2236 4.4642
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 -0.1535 4.2219 -0.5953 29.1968
NCI-H660 CTRP2 0.1989 18.213 -6.4786 39.5973
VCaP CTRP2 1.488 9.0863 -0.852 25.2346
DU145 CTRP2 2.2425 7.1191 0.811 17.2128
PaCa-3 CTRP2 3.709 9.5906 0.9586 13.2974
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -1.3538 -0.9805 -1.3538 35.7042
A-253 CTRP2 2.5615 7.3906 0.9952 15.697
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 -1.379 0.0083 -1.3792 35.8729
SNU-620 CTRP2 -1.3562 -0.8146 -1.3562 35.72
23132/87 CTRP2 -1.3067 0.1297 -1.3071 35.3912
ECC12 CTRP2 -1.1988 0.6804 -1.2027 34.6831
NCC-StC-K140 CTRP2 -0.5245 2.3362 -0.6027 30.4353
IM95 CTRP2 -0.4876 1.0299 -0.4897 29.9347
GSS CTRP2 -0.404 1.9628 -0.4395 29.489
SH-10-TC CTRP2 0.0016 2.5646 -0.0717 26.9126
ECC10 CTRP2 0.2555 3.1401 0.1121 25.4615
HuG1-N CTRP2 0.656 4.3038 0.2634 23.6773
NUGC-4 CTRP2 0.7091 4.0939 0.3825 23.0881
OCUM-1 CTRP2 0.7744 7.5423 -0.8634 27.245
Fu97 CTRP2 1.3004 4.723 0.8289 19.6901
NUGC-3 CTRP2 1.5003 5.2328 0.8584 19.0044
NCI-N87 CTRP2 1.6815 6.5311 0.5108 19.8301
AGS CTRP2; CTRP1 1.9814 6.5435 0.8118 17.8775
HGC-27 CTRP2 1.9957 7.3173 0.4742 19.1484
SNU-216 CTRP2 2.2069 7.6887 0.5092 18.4804
SNU-1 CTRP2 2.3437 9.1321 -0.0499 20.2629
MKN74 CTRP2 2.3662 7.9387 0.5454 17.9472
SNU-601 CTRP2 2.55 6.2054 1.5386 13.5441
KATO III CTRP2 2.7759 7.5944 1.1028 14.7541
LMSU CTRP2 2.954 7.7511 1.1945 13.9696
Hs 746.T CTRP2 3.6193 9.8916 0.7312 14.3939
MKN1 CTRP2 4.4263 9.8109 1.4418 9.938
SNU-719 CTRP2 5.0398 10.7144 1.4651 8.7831
MKN7 CTRP2 5.2301 13.9234 0.0225 14.0713
GSU CTRP2 5.2545 12.2806 0.853 10.8743
MKN45 CTRP2 5.3955 6.4068 3.67 0.1446
SNU-668 CTRP2 5.6324 9.8807 2.2834 4.6083
KE-39 CTRP2 8.2877 17.867 0.2307 8.8911
SNG-M CTRP2 -1.2565 5.8264 -2.3218 37.8763
SNU-685 CTRP2 2.0122 6.1687 1.0092 17.0263
SNU-1077 CTRP2 6.1932 9.9802 2.5794 2.838
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-238 CTRP2 -0.4587 1.1906 -0.4626 29.7479
8305C CTRP2 -0.3543 2.7642 -0.4805 29.4633
CAL-62 CTRP2 -0.2129 2.8431 -0.3413 28.5297
SW579 CTRP2 0.3157 3.2016 0.1656 25.0835
B-CPAP CTRP2 0.3268 3.2477 0.1688 25.0372
BHT-101 CTRP2 0.3594 3.2279 0.2079 24.7973
ML-1 [Human leukemia] CTRP2 2.1478 6.0577 1.197 15.9341
TT CTRP2 2.8695 7.2867 1.3402 13.5723
TT2609-C02 CTRP2 3.1709 7.9105 1.3171 12.9798
CGTH-W-1 CTRP2 3.3125 8.141 1.332 12.6072
8505C CTRP2 3.4672 9.0837 1.0016 13.6256
FTC-133 CTRP2 6.7293 15.4738 0.3475 10.5195
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PE/CA-PJ49 CTRP2 -0.9803 1.37 -1.0005 33.2802
CAL-27 CTRP2 -0.8287 0.1341 -0.8287 32.2025
SCC-4 CTRP2 -0.6889 4.1235 -1.1514 32.7616
YD-10B CTRP2 -0.6772 0.1062 -0.6772 31.192
HSC-2 CTRP2 -0.613 2.8548 -0.7743 31.3006
BICR 22 CTRP2 -0.5085 6.2671 -1.6829 33.6786
CAL-33 CTRP2 -0.0785 2.8781 -0.2025 27.6193
PE/CA-PJ34 (clone C12) CTRP2 0.1003 2.9703 -0.0254 26.4343
PE/CA-PJ15 CTRP2 0.236 3.811 -0.0577 26.1144
Detroit 562 CTRP2 0.8255 5.8156 -0.0866 24.4323
SNU-1076 CTRP2 0.9026 4.6611 0.4186 22.373
BICR 6 CTRP2 1.0549 4.0025 0.7852 20.5838
HSC-3 CTRP2 1.21 5.7266 0.3564 21.7099
BICR 18 CTRP2 1.6166 5.7653 0.7697 19.0168
BICR 16 CTRP2 1.6973 6.1874 0.6763 19.1543
SCC-9 CTRP2; CTRP1 1.7638 6.7856 0.4824 19.7196
BICR 56 CTRP2 2.2993 7.9069 0.4959 18.3032
FaDu CTRP2 3.3747 8.7262 1.0976 13.4323
SCC-25 CTRP2 3.419 8.4301 1.2839 12.5756
BHY CTRP2 3.469 9.5503 0.7708 14.5504
BICR 31 CTRP2 3.5467 10.8909 0.1699 16.7277
PE/CA-PJ41 (clone D2) CTRP2 4.4617 12.7625 -0.0027 15.5532
SNU-899 CTRP2 4.4945 9.2582 1.7708 8.4555
YD-8 CTRP2 5.5291 7.548 3.28 1.0626
SNU-46 CTRP2 6.1227 10.8144 2.1574 4.4788
SNU-1066 CTRP2 6.1858 10.6423 2.2754 3.9597
HSC-4 CTRP2 7.192 14.9691 0.8927 7.9023
SNU-1041 CTRP2 7.3532 12.6982 2.0252 3.637
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-112 CTRP2 -0.4547 0.0187 -0.4547 29.7077
5637 CTRP2 -0.2698 3.776 -0.6005 29.591
SCaBER CTRP2 -0.0346 3.149 -0.2033 27.4802
253J CTRP2 0.3116 4.8949 -0.3009 26.7277
VM-CUB-1 CTRP2 0.6104 3.5952 0.4029 23.3215
647V CTRP2 0.7966 4.208 0.4451 22.5963
JMSU-1 CTRP2 0.8346 4.1146 0.5136 22.2339
SW1710 CTRP2 1.4602 9.6422 -1.1417 26.2385
BC-3C CTRP2 1.4746 6.1894 0.4441 20.6438
UM-UC-3 CTRP2 2.0743 5.5193 1.3515 15.5253
U-BLC1 CTRP2 2.2925 7.1466 0.8476 16.9435
T24 CTRP2 2.43 8.1154 0.5222 17.8824
RT-4 CTRP2 2.761 6.3169 1.6968 12.3821
UM-UC-1 CTRP2 2.8151 8.2518 0.8208 15.7953
639V CTRP2 3.355 8.2631 1.3096 12.6072
HT-1376 CTRP2 4.0284 8.0845 1.9813 8.4355
TCCSUP CTRP2 4.3333 9.5059 1.5196 9.7869
J82 CTRP2 4.8125 10.4751 1.4121 9.3794
KU-19-19 CTRP2 5.0116 15.8318 -1.0954 18.3145
KMBC-2 CTRP2 6.3717 14.0667 0.7798 9.4313
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 -0.2566 0.2339 -0.2566 28.387

References

1 Synthesis and preclinical evaluations of 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one monosodium phosphate (CHM-1-P-Na) as a potent antitumo... J Med Chem. 2010 Feb 25;53(4):1616-26.