Details of the Drug

General Information of Drug (ID: DM53KRA)

Drug Name

ALF-421

Synonyms

CORM-A1; Macromolecular carrier-linked carbon monoxide releasing molecules (inflammation); Carbon monoxide-releasing molecules (inflammatory diseases), Alfama; Macromolecular carrier-linked CORMs (inflammation), Alfama; Macromolecular carrier-linked carbon monoxide releasing molecules (inflammation), Alfama

Indication

Disease Entry	ICD 11	Status	REF
Acute liver failure	DB91	Investigative	[1]
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Cross-matching ID

TTD ID: D0W7FG

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tumor necrosis factor receptor type I (TNF-R1)	TTG043C	TNR1A_HUMAN	Modulator	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Secretion of a TNFR:Fc fusion protein following pulmonary administration of pseudotyped adeno-associated virus vectors. J Virol. 2004 Nov;78(22):12355-65.