Details of the Drug

General Information of Drug (ID: DM54XJO)

Drug Name
UMI-77
Synonyms
518303-20-3; C18H14BrNO5S2; MLS001196198; SMR000558497; 2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynaphthalen-2-yl]sulfanylacetic acid; [(4-{[(4-bromophenyl)sulfonyl]amino}-1-hydroxy-2-naphthyl)thio]acetic acid; AC1LKK7D; UMI77; cid_992586; GTPL8105; SCHEMBL14842934; CHEMBL1331211; BDBM53290; EX-A762; AOB6936; MolPort-000-682-969; BCP09696; ZINC4149952; STK238370; 2780AH; s7531; AKOS001057042; SB19399; CS-5046; MCULE-2580729398; NCGC00386409-01; UMI-77, > HY-18628; DA-42224; BC600617; AK547843; EU-0015042
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
Chemical Identifiers
Formula
C18H14BrNO5S2
Canonical SMILES
C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br
InChI
1S/C18H14BrNO5S2/c19-11-5-7-12(8-6-11)27(24,25)20-15-9-16(26-10-17(21)22)18(23)14-4-2-1-3-13(14)15/h1-9,20,23H,10H2,(H,21,22)
InChIKey
WUGANDSUVKXMEC-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
992586
TTD ID
D05RDP

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 2.7523 3.9994 2.4402 7.4947
ES7 GDSC2 0.6305 3.5707 0.3131 28.6372
HOS GDSC2 1.0556 1.8042 1.0547 22.7476
EW-1 GDSC2 1.1174 3.4855 0.8695 23.4301
A-673 GDSC2 1.6271 2.9765 1.5539 17.3861
CADO-ES1 GDSC2 1.6577 3.0835 1.5649 17.183
H-EMC-SS GDSC2 1.8174 3.4187 1.6526 15.9713
EW-7 GDSC2 2.0993 9.6665 -0.9191 28.0042
TC-71 GDSC2 2.1532 3.4532 2.0083 12.5
EW-22 GDSC2 2.224 3.595 2.0394 12.0118
ES4 GDSC2 2.2314 3.9355 1.922 12.6498
SK-ES-1 GDSC2 2.2562 3.8673 1.9749 12.2406
EW-11 GDSC2 2.307 3.9151 2.0104 11.8228
EW-16 GDSC2 2.3102 3.5494 2.1482 11.0237
EW-3 GDSC2 2.3838 4.2344 1.9586 11.8138
NOS-1 [Human HNSCC] GDSC2 2.413 3.8131 2.163 10.4975
EW-24 GDSC2 2.4205 3.3324 2.3353 9.4952
SJSA-1 GDSC2 2.5737 4.6271 1.9748 10.9866
EW-18 GDSC2 2.6078 3.6286 2.4416 8.0746
NY GDSC2 2.746 4.768 2.0766 9.7356
ES6 GDSC2 2.8176 4.0522 2.4826 6.9891
ES1 GDSC2 2.8181 4.0029 2.5054 6.8493
SK-PN-DW GDSC2 2.9749 4.9158 2.2201 8.0553
MHH-ES-1 GDSC2 3.1542 5.0037 2.3375 6.7385
EW-13 GDSC2 3.1857 6.0611 1.8372 9.7971
CAL-72 GDSC2 3.2429 6.8103 1.5114 11.6581
SaOS-2 GDSC2 3.3283 4.7652 2.6056 4.5169
ES8 GDSC2 3.5094 5.4402 2.4147 5.2217
HuO9 GDSC2 3.7612 11.8892 -0.6013 21.4272
G-292 clone A141B1 GDSC2 3.807 9.5829 0.586 15.4723
CHSA8926 GDSC2 3.8289 8.7525 1.0167 12.9778
MG-63 GDSC2 3.8346 13.4602 -1.3266 24.1272
U2OS GDSC2 4.5003 7.9744 1.8893 6.1491
CAL-78 GDSC2 4.7823 6.7934 2.5991 1.696
HuO-3N1 GDSC2 5.6609 8.228 2.4358 1.485
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-GT-4 GDSC2 2.1343 3.5849 1.9456 12.9324
KYSE-220 GDSC2 2.382 3.7737 2.1451 10.7312
KYSE-50 GDSC2 2.7565 3.8558 2.5072 7.0794
OACP4 C GDSC2 3.0723 4.4903 2.5186 5.862
ESO-51 GDSC2 3.3914 6.026 2.0274 7.9939
FLO-1 GDSC2 3.5431 8.4101 0.9597 14.1032
KYAE-1 GDSC2 4.0686 9.0337 1.062 12.0822
ESO-26 GDSC2 4.6902 7.8292 2.0809 4.6515
OACM5.1 C GDSC2 6.5699 8.722 2.6254 0.3505
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 2.1751 3.4052 2.0467 12.1899
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC2 1.382 8.8726 -1.1992 31.709
TGW GDSC2 1.9511 4.189 1.5242 16.119
NB1 GDSC2 2.0347 3.3781 1.9014 13.6231
SJNB-14 GDSC2 2.2449 3.6552 2.0413 11.9104
SJNB-12 GDSC2 2.2794 4.3695 1.7925 13.2135
SJNB-10 GDSC2 2.3916 4.3941 1.897 12.1501
Kelly GDSC2 2.492 3.4078 2.3913 8.864
KP-N-YN GDSC2 2.5808 4.4098 2.0819 10.3102
CHP-134 GDSC2 2.6027 3.4105 2.5112 7.7051
SJNB-13 GDSC2 2.6889 6.1311 1.3603 14.3508
SK-N-SH GDSC2 2.7368 3.6353 2.5771 6.751
NH-12 GDSC2 2.815 5.1152 1.9744 10.1286
SK-N-FI GDSC2 2.916 4.1228 2.5478 6.2251
SJNB-7 GDSC2 3.0068 4.3099 2.5458 5.9142
NB(TU)1 GDSC2 3.1073 4.8616 2.3667 6.7023
SiMa GDSC2 3.1101 8.2199 0.6943 16.9137
SK-N-AS GDSC2 3.1493 4.5499 2.5587 5.3585
GOTO GDSC2 3.3985 5.4098 2.3411 5.9905
SK-N-BE(2)-M17 GDSC2 3.512 6.0108 2.1324 6.995
GI-ME-N GDSC2 3.5527 6.5168 1.9125 8.2683
SK-N-DZ GDSC2 3.5622 4.9874 2.6799 3.4175
IMR-5 GDSC2 3.693 6.0934 2.232 5.8934
CHP-212 GDSC2 4.9465 12.7358 -0.1093 16.1054
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 2.9707 4.1808 2.5735 5.8698
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-175-VII GDSC2 0.935 2.4354 0.8948 24.1575
OCUB-M GDSC2 0.9786 2.1706 0.9644 23.5872
Hs 578T GDSC2 1.2554 4.1883 0.7824 23.2838
CAL-51 GDSC2 1.9361 3.1388 1.8553 14.3274
DU4475 GDSC2 2.2075 3.6346 2.008 12.261
MDA-MB-453 GDSC2 2.3186 3.4799 2.18 10.8093
MDA-MB-468 GDSC2 2.3321 3.2747 2.2543 10.341
BT-549 GDSC2 2.338 4.259 1.9007 12.3392
HCC1187 GDSC2 2.3894 3.6805 2.1879 10.4554
MDA-MB-415 GDSC2 2.4799 3.1881 2.4358 8.6784
CAL-85-1 GDSC2 2.5036 3.5057 2.3727 8.9154
CAMA-1 GDSC2 2.5051 3.2119 2.458 8.4419
MRK-nu-1 GDSC2 2.5487 3.4007 2.4554 8.2555
HCC38 GDSC2 2.5585 4.9879 1.7907 12.1669
CAL-120 GDSC2 2.5614 3.6138 2.3973 8.5254
HCC2157 GDSC2 2.6123 4.2429 2.1892 9.5428
COLO 824 GDSC2 2.6596 4.073 2.3129 8.6174
CAL-148 GDSC2 2.6841 3.3767 2.6102 6.7933
EFM-19 GDSC2 2.6962 3.7696 2.4803 7.4812
UACC-812 GDSC2 2.8261 3.6996 2.6456 5.983
Evsa-T GDSC2 2.8399 4.3017 2.3891 7.4751
HCC1143 GDSC2 2.8963 4.3103 2.4399 6.9591
MDA-MB-231 GDSC2 2.9102 4.2617 2.4765 6.6838
JIMT-1 GDSC2 3.1421 4.4543 2.5996 5.1244
HCC1937 GDSC2 3.2337 7.2334 1.2922 13.0297
EFM-192A GDSC2 3.3549 6.9089 1.5558 11.053
AU565 GDSC2 3.3642 7.2445 1.3957 12.0122
HCC1419 GDSC2 3.4223 5.5135 2.3086 6.1293
MFM-223 GDSC2 3.4619 4.8932 2.6497 3.8661
MDA-MB-436 GDSC2 3.4651 5.788 2.2061 6.6591
HCC1806 GDSC2 3.6211 8.4803 0.9876 13.7192
HCC1500 GDSC2 3.6623 5.8514 2.3284 5.3675
HDQ-P1 GDSC2 3.8382 11.0082 -0.0999 18.9171
MDA-MB-157 GDSC2 3.9193 6.4434 2.2267 5.3772
T-47D GDSC2 3.9739 10.616 0.203 17.0401
HCC70 GDSC2 4.1172 5.979 2.5832 2.8073
MCF-7 GDSC2 4.1932 7.5457 1.8847 6.8446
HCC1395 GDSC2 4.4896 7.6814 2.0216 5.3858
MDA-MB-361 GDSC2 4.6675 8.4987 1.7508 6.6218
BT-20 GDSC2 4.6928 8.8986 1.5768 7.5906
BT-474 GDSC2 4.7265 6.4693 2.7073 1.2511
ZR-75-30 GDSC2 4.7849 7.3809 2.3431 3.0172
HCC1954 GDSC2 4.9431 7.9149 2.1945 3.5751
HCC1428 GDSC2 5.6509 13.0753 0.2231 12.9128
BT-483 GDSC2 6.9922 16.488 -0.5113 13.6325
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-392MG GDSC2 1.5059 2.9854 1.4207 18.6648
LN-18 GDSC2 1.8609 4.0839 1.4698 16.81
MOG-G-CCM GDSC2 2.3553 3.9357 2.0533 11.3734
SF539 GDSC2 2.3797 4.3146 1.9197 12.061
AM-38 GDSC2 2.3877 3.7675 2.1536 10.659
SW1088 GDSC2 2.4547 3.1607 2.4141 8.9128
DK-MG GDSC2 2.463 4.0285 2.1285 10.4929
MOG-G-UVW GDSC2 2.4725 3.482 2.3467 9.1982
YH-13 GDSC2 2.5194 4.9168 1.786 12.3377
M059J GDSC2 2.5581 3.6461 2.3818 8.6281
U-251MG GDSC2 2.692 3.4999 2.5788 6.9326
GI-1 GDSC2 2.7051 3.6001 2.5566 7.0028
D-263MG GDSC2 2.7217 3.7303 2.5232 7.1263
SW1783 GDSC2 2.9111 5.9986 1.6275 11.9702
GB-1 GDSC2 2.9832 4.9305 2.2204 8.0257
D283 Med GDSC2 3.0223 8.2871 0.5854 17.7954
CAS-1 GDSC2 3.1205 4.1679 2.7212 4.433
ONS-76 GDSC2 3.156 5.6752 2.0043 8.8356
PFSK-1 GDSC2 3.181 13.762 -2.016 28.3016
8-MG-BA GDSC2 3.234 5.6227 2.0975 8.0108
KINGS-1 GDSC2 3.4025 5.2677 2.4154 5.5097
SF268 GDSC2 3.4999 5.0334 2.6096 4.0186
42-MG-BA GDSC2 3.5157 8.4461 0.9195 14.4147
DBTRG-05MG GDSC2 3.7182 5.2883 2.6462 3.2544
Becker GDSC2 3.8692 5.8109 2.4987 3.8195
LN-229 GDSC2 3.9571 7.0382 1.9629 6.9178
H4 GDSC2 4.0184 6.1138 2.4551 3.7631
LN-405 GDSC2 4.2235 8.3603 1.5089 9.0501
GaMG GDSC2 4.3296 13.0207 -0.7154 20.3754
KALS-1 GDSC2 4.5702 7.4872 2.165 4.389
T98G GDSC2 4.7567 9.3879 1.3853 8.5701
U-118MG GDSC2 4.8414 8.8328 1.7066 6.5286
SK-MG-1 GDSC2 4.8994 9.5825 1.3886 8.2476
Daoy GDSC2 4.9007 10.6455 0.8778 11.1274
A-172 GDSC2 5.1254 9.4997 1.5755 6.7277
KS-1 [Human Krukenberg tumour] GDSC2 5.9405 8.4347 2.4799 1.0812
U-87MG ATCC GDSC2 6.6607 18.3037 -1.602 18.55
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC2 2.4093 3.3139 2.3282 9.5851
ETK-1 GDSC2 4.99 7.7025 2.316 2.8513
TGBC24TKB GDSC2 6.1134 8.2995 2.6026 0.5862
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KLE GDSC2 2.1556 6.1376 0.854 19.2423
ESS-1 GDSC2 2.2127 3.0426 2.1747 11.3267
MFE-319 GDSC2 2.301 6.2375 0.9453 18.1832
MFE-280 GDSC2 4.114 7.844 1.6822 8.263
RL95-2 GDSC2 4.1145 6.8812 2.1517 5.3954
AN3-CA GDSC2 4.5729 7.5852 2.1208 4.6404
EN GDSC2 5.1866 6.6918 2.8249 0.4377
MFE-296 GDSC2 5.6959 8.201 2.4627 1.3437
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 127 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AMO1 GDSC2 -0.0645 1.2412 -0.0685 34.0033
EJM GDSC2 0.7219 2.957 0.5751 26.8476
BE-13 GDSC2 1.3856 3.5743 1.1348 20.7658
SUP-B15 GDSC2 1.5934 3.3807 1.4192 18.2667
MLMA GDSC2 1.6908 6.7636 0.1059 25.0411
MN-60 GDSC2 1.7313 3.0875 1.6439 16.416
HL-60 GDSC2 1.8845 3.1514 1.7963 14.8844
SR GDSC2 1.9607 3.2856 1.8462 14.2618
KE-37 GDSC2 1.9742 3.275 1.8637 14.1046
JVM-2 GDSC2 1.9953 9.1965 -0.7829 27.8458
OCI-M1 GDSC2 2.0016 7.2336 0.1803 23.4698
KMOE-2 GDSC2 2.0156 7.6334 -0.0001 24.3136
MHH-CALL-2 GDSC2 2.0164 5.312 1.1038 18.3191
P32/ISH GDSC2 2.0336 3.3789 1.9 13.6356
MV4-11 GDSC2 2.0471 4.7558 1.3849 16.546
KY821 GDSC2 2.0699 3.7948 1.8024 14.0201
U-698-M GDSC2 2.1286 3.5404 1.954 12.9101
Mono-Mac-6 GDSC2 2.137 4.1932 1.7186 14.2222
DND-41 GDSC2 2.1546 3.6346 1.9507 12.8142
JVM-3 GDSC2 2.1893 3.2845 2.0959 11.8567
YT GDSC2 2.2024 3.1206 2.1487 11.5129
MOLT-16 GDSC2 2.2179 3.4333 2.0849 11.7867
Karpas-299 GDSC2 2.2218 3.8502 1.9447 12.5595
GR-ST GDSC2 2.2248 4.7144 1.5846 14.6652
EoL-1 GDSC2 2.2314 3.7879 1.9785 12.3254
NKM-1 GDSC2 2.2817 3.6937 2.0672 11.6042
L-540 GDSC2 2.2956 3.3056 2.2063 10.7691
SU-DHL-5 GDSC2 2.2975 3.342 2.1984 10.8034
MOLT-13 GDSC2 2.3121 13.1124 -2.4384 32.1228
VL51 GDSC2 2.3191 4.5882 1.7368 13.3899
Karpas-231 GDSC2 2.3402 3.4259 2.2204 10.4891
MM1.S GDSC2 2.346 4.0206 2.0091 11.669
Karpas-1106P GDSC2 2.3667 3.725 2.1471 10.7848
Karpas-45 GDSC2 2.3778 3.3801 2.2751 10.0189
L-428 GDSC2 2.3847 3.691 2.1789 10.5266
RPMI-6666 GDSC2 2.4062 3.3472 2.3155 9.6684
BL-41 GDSC2 2.4121 3.7165 2.199 10.2949
BV-173 GDSC2 2.4153 5.1555 1.5718 14.0243
VAL GDSC2 2.4315 4.0859 2.0715 10.9561
IM-9 GDSC2 2.441 4.1325 2.0616 10.9757
Karpas-422 GDSC2 2.4835 3.892 2.2064 9.953
L-1236 GDSC2 2.4927 3.7855 2.2586 9.6119
DB GDSC2 2.4928 4.8231 1.8036 12.3283
SU-DHL-6 GDSC2 2.4939 3.6763 2.3016 9.36
RS4;11 GDSC2 2.5171 5.1238 1.686 12.9575
GA-10 GDSC2 2.5293 3.3753 2.4418 8.4181
EB2 GDSC2 2.5424 3.3622 2.4598 8.26
BC-1 GDSC2 2.5561 3.5105 2.428 8.3753
A3/Kawakami GDSC2 2.5641 3.9322 2.2745 9.2252
P12-Ichikawa GDSC2 2.5781 4.0985 2.218 9.5038
MOLP-8 GDSC2 2.6034 4.4557 2.0835 10.215
JSC-1 GDSC2 2.6668 3.6198 2.5082 7.4423
Karpas-620 GDSC2 2.6762 4.1835 2.2806 8.7472
ST486 GDSC2 2.7007 3.9501 2.4089 7.8839
RC-K8 GDSC2 2.7105 4.7897 2.032 10.1372
CTV-1 GDSC2 2.712 3.6617 2.5403 7.067
PF-382 GDSC2 2.7396 4.9902 1.9638 10.4558
OCI-AML-2 GDSC2 2.7554 3.4831 2.6532 6.2374
EM-2 GDSC2 2.8101 3.9064 2.5404 6.6704
KOPN-8 GDSC2 2.812 4.6234 2.2092 8.6828
SUP-M2 GDSC2 2.8123 3.4804 2.7157 5.6371
ALL-PO GDSC2 2.8399 4.6104 2.2422 8.3799
P30/OHK GDSC2 2.8636 3.8836 2.6051 6.0749
HDLM-2 GDSC2 2.868 4.5073 2.3186 7.8087
ATN-1 GDSC2 2.8734 4.6185 2.2703 8.0886
Granta-519 GDSC2 2.8851 4.2376 2.4635 6.854
KMS-12-BM GDSC2 2.9422 4.2313 2.5219 6.2896
HAL-01 GDSC2 2.9637 4.6237 2.3528 7.2639
OCI-AML-3 GDSC2 2.991 4.2775 2.5465 5.9647
Raji GDSC2 3.0005 6.0402 1.6864 11.3164
Loucy GDSC2 3.0605 5.1106 2.2014 7.8926
CML-T1 GDSC2 3.0676 4.5655 2.4772 6.1367
Jiyoye GDSC2 3.0782 4.4497 2.544 5.6832
Ramos.2G6.4C10 GDSC2 3.0875 4.2895 2.6312 5.1061
HH [Human lymphoma] GDSC2 3.0956 4.5386 2.5161 5.8008
MHH-PREB-1 GDSC2 3.0987 4.1732 2.6985 4.6479
WIL2 NS GDSC2 3.1372 4.5254 2.5601 5.3891
K-562 GDSC2 3.1557 4.449 2.6145 4.9872
SU-DHL-8 GDSC2 3.1751 4.2219 2.7444 4.1073
BALL-1 GDSC2 3.1823 5.2066 2.2609 7.1349
ARH-77 GDSC2 3.1929 4.6203 2.5623 5.1983
LC4-1 GDSC2 3.193 5.3016 2.2227 7.3437
GDM-1 GDSC2 3.1958 7.3605 1.1966 13.7218
Hs 445 GDSC2 3.201 5.1186 2.3209 6.6982
CCRF-CEM GDSC2 3.2158 4.6856 2.5498 5.2064
NCI-H929 GDSC2 3.2346 5.7735 2.0226 8.4819
JJN-3 GDSC2 3.2353 5.0268 2.3963 6.1172
U266B1 GDSC2 3.2425 4.397 2.7169 4.0682
RPMI-8402 GDSC2 3.2442 6.4757 1.6798 10.6071
CA46 GDSC2 3.2723 5.2436 2.3194 6.4929
Jurkat GDSC2 3.2768 5.7475 2.0713 8.0488
DEL GDSC2 3.3124 4.4748 2.7375 3.7281
RPMI-8226 GDSC2 3.3165 5.4357 2.2605 6.7359
WSU-DLCL2 GDSC2 3.3199 5.0759 2.4432 5.5692
CESS GDSC2 3.3205 6.067 1.9482 8.6973
HC-1 GDSC2 3.3265 6.4901 1.7416 9.9781
WSU-NHL GDSC2 3.3308 4.7719 2.6043 4.518
MOLT-4 GDSC2 3.3537 4.7325 2.6429 4.2078
ME1 GDSC2 3.3671 4.6633 2.6885 3.8812
A4/Fukuda GDSC2 3.3728 4.8925 2.5786 4.5606
SUP-T1 GDSC2 3.3856 4.9084 2.5811 4.5087
L-363 GDSC2 3.3894 5.9027 2.0873 7.6213
ML-2 GDSC2 3.4013 4.8996 2.5982 4.3568
Namalwa GDSC2 3.4073 4.7837 2.661 3.9431
Reh GDSC2 3.4397 4.746 2.7055 3.5739
SU-DHL-10 GDSC2 3.5249 4.737 2.7756 2.9119
SUP-HD1 GDSC2 3.551 9.3547 0.4943 16.6952
ALL-SIL GDSC2 3.594 5.8577 2.273 5.8904
KG-1 GDSC2 3.616 13.3058 -1.4271 25.1008
H9 GDSC2 3.6598 5.306 2.5954 3.7057
Daudi GDSC2 3.696 5.6512 2.4524 4.5085
MEG-01 GDSC2 3.7079 5.5218 2.5248 4.0296
MOLM-13 GDSC2 3.7441 5.7763 2.4263 4.5549
KCL-22 GDSC2 3.7926 5.8001 2.4498 4.2946
LAMA-84 GDSC2 3.8413 6.1928 2.2929 5.151
697 GDSC2 4.0384 5.8621 2.5878 2.9315
DG-75 GDSC2 4.1359 10.2035 0.5337 14.8707
OPM-2 GDSC2 4.1364 6.5213 2.3395 4.2123
SCC-3 GDSC2 4.192 5.923 2.6551 2.2629
NALM-6 GDSC2 4.2531 6.219 2.5562 2.7159
TK [Human B-cell lymphoma] GDSC2 4.2854 7.2416 2.0952 5.368
KM-H2 GDSC2 4.3446 7.1251 2.1902 4.6788
Ku812 GDSC2 4.5253 6.5983 2.5446 2.332
SK-MM-2 GDSC2 4.6122 6.6772 2.5584 2.1298
NOMO-1 GDSC2 5.4021 6.7177 2.8977 0.1834
P31/FUJ GDSC2 5.441 6.7716 2.8931 0.1809
TUR GDSC2 5.7029 7.1967 2.8405 0.2025
⏷ Show the Full List of 127 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW13 GDSC2 2.0965 3.7996 1.8294 13.7524
BFTC-909 GDSC2 3.2753 6.4963 1.6957 10.4157
KTCTL-195 GDSC2 3.3963 6.0671 2.0108 8.0843
SN12C GDSC2 3.5554 6.9831 1.6821 9.7011
CAL-54 GDSC2 3.6772 6.8105 1.8641 8.2373
KMRC-1 GDSC2 3.7592 6.8042 1.9304 7.6101
VMRC-RCZ GDSC2 3.8229 9.3888 0.6953 14.8252
769-P GDSC2 3.995 6.6477 2.1811 5.4833
A-498 GDSC2 4.0468 5.8458 2.6009 2.838
ACHN GDSC2 4.4057 6.3589 2.5833 2.3094
LB996-RCC GDSC2 4.4208 7.0755 2.2628 4.102
RCC10RGB GDSC2 4.4379 6.8467 2.38 3.3931
KMRC-20 GDSC2 4.6886 7.8211 2.0837 4.6386
A-704 GDSC2 4.9405 7.6948 2.2916 3.0541
TK-10 GDSC2 5.2698 9.9129 1.4738 7.0267
786-O GDSC2 5.3695 10.502 1.2612 8.0206
OS-RC-2 GDSC2 6.0862 14.1912 -0.0175 13.1723
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320HSR GDSC2 1.3343 4.296 0.8263 22.6977
C2BBe1 GDSC2 1.945 3.3461 1.8126 14.5163
RCM-1 [Human ESC] GDSC2 2.0432 4.4645 1.507 15.8425
LS1034 GDSC2 2.1661 6.1979 0.8352 19.3112
NCI-H747 GDSC2 2.314 4.0901 1.9469 12.1636
SW48 GDSC2 2.3433 4.8843 1.6268 13.9586
LS411N GDSC2 2.3642 3.8616 2.0921 11.1114
CaR-1 GDSC2 2.5005 4.8444 1.8013 12.3144
LS123 GDSC2 2.5524 3.5383 2.4145 8.4671
SW626 GDSC2 2.5877 4.1934 2.1862 9.6559
SW1417 GDSC2 2.6474 3.5462 2.5143 7.4912
SW1116 GDSC2 2.7163 3.7373 2.5146 7.1985
T84 GDSC2 2.8147 4.5948 2.2255 8.5726
RKO GDSC2 2.8544 4.3503 2.3804 7.4759
HCT 15 GDSC2 2.9488 5.7167 1.801 10.7662
CL-11 GDSC2 3.0537 4.5463 2.474 6.2028
SW837 GDSC2 3.252 4.8995 2.4741 5.5747
SW620 GDSC2 3.2636 5.0098 2.4289 5.826
HT-29 GDSC2 3.3662 4.8978 2.5705 4.6305
SNU-C5 GDSC2 3.4557 6.6142 1.7859 9.3308
SK-CO-1 GDSC2 3.4627 5.5226 2.3366 5.8412
CW-2 GDSC2 3.4952 7.3306 1.4601 11.2415
SW1463 GDSC2 3.5491 5.3938 2.4687 4.7768
HCT 116 GDSC2 3.7118 6.8216 1.8854 8.0135
COLO205 GDSC2 4.0744 7.9266 1.6126 8.7825
LS180 GDSC2 4.1281 6.5297 2.3299 4.2868
CCK-81 GDSC2 4.1577 6.4334 2.3955 3.834
HT-55 GDSC2 4.1679 6.8964 2.1811 5.1001
SW948 GDSC2 4.4579 12.6755 -0.4451 18.8647
SNU-C2B GDSC2 4.6405 9.004 1.4905 8.2087
SNU-C1 GDSC2 4.7273 7.5564 2.2297 3.7383
MDST8 GDSC2 4.7336 8.6894 1.7039 6.7615
SNU-61 GDSC2 4.7347 6.8097 2.5671 1.9155
COLO 678 GDSC2 4.7774 7.0861 2.4698 2.3548
HCC2998 GDSC2 4.8747 11.3292 0.527 13.0813
SNU-175 GDSC2 5.0206 8.3595 2.0385 4.3072
NCI-H716 GDSC2 5.27 7.2232 2.6574 0.9452
GP5d GDSC2 5.4372 7.6045 2.5821 1.0963
DiFi GDSC2 5.445 8.2478 2.3224 2.2182
SNU-407 GDSC2 5.7335 7.8076 2.6316 0.709
LoVo GDSC2 6.1537 8.0181 2.7189 0.2972
KM12 GDSC2 6.7802 17.7446 -1.2506 17.0174
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 3.805 5.5904 2.5607 3.5833
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 GDSC2 1.9019 10.2302 -1.3769 30.3581
HLE GDSC2 2.8204 5.2691 1.9043 10.5465
JHH-1 GDSC2 2.8539 3.4641 2.7663 5.1705
SNU-449 GDSC2 3.1758 4.3384 2.6873 4.4645
JHH-6 GDSC2 3.4482 5.8096 2.1817 6.8592
JHH-2 GDSC2 3.5825 12.3999 -1.0018 23.594
SNU-423 GDSC2 3.7858 12.0102 -0.6419 21.5332
Hep-G2/C3A GDSC2 4.0268 5.7284 2.6431 2.6287
SK-HEP-1 GDSC2 4.5829 8.8096 1.5446 8.0158
Huh-7 GDSC2 4.808 9.8816 1.1827 9.6228
JHH-7 GDSC2 5.1857 8.3611 2.1338 3.5235
HuH-1 GDSC2 5.2132 6.5503 2.8867 0.267
JHH-4 GDSC2 5.2977 11.8388 0.5764 11.8728
SNU-387 GDSC2 5.5783 15.6611 -1.0831 18.8718
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 131 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IA-LM GDSC2 1.1696 2.8588 1.0814 22.0537
COR-L32 GDSC2 1.3858 3.165 1.2497 20.1401
NCI-H209 GDSC2 1.5865 3.1376 1.4749 17.9971
SHP-77 GDSC2 1.6918 4.056 1.2997 18.4995
NCI-H1869 GDSC2 1.7064 3.3617 1.5478 17.0491
NCI-H835 GDSC2 1.7229 3.2935 1.5845 16.7741
DMS 114 GDSC2 1.782 3.2834 1.6517 16.1382
NCI-H1299 GDSC2 1.8344 4.5998 1.2324 18.291
HARA [Human squamous cell lung carcinoma] GDSC2 1.8392 3.3826 1.6868 15.6853
NCI-H211 GDSC2 1.8558 3.1623 1.7625 15.1993
HCC44 GDSC2 1.8995 6.4531 0.4559 22.4199
NCI-H1876 GDSC2 2.021 3.5311 1.84 14.0228
NCI-H727 GDSC2 2.0965 4.0882 1.7184 14.3901
COR-L23 GDSC2 2.1386 3.569 1.9555 12.8581
NCI-H1581 GDSC2 2.1629 3.829 1.8897 13.1242
NCI-H1963 GDSC2 2.17 3.9199 1.8627 13.2496
EBC-1 GDSC2 2.186 4.8488 1.4849 15.4108
NCI-H1693 GDSC2 2.238 4.0702 1.8752 12.8942
Calu-6 GDSC2 2.2524 4.3843 1.7582 13.5243
KNS-62 GDSC2 2.2745 3.0396 2.2417 10.6795
NCI-H1755 GDSC2 2.3379 3.6013 2.1606 10.833
Lu-165 GDSC2 2.3434 3.1181 2.302 10.0338
NCI-H841 GDSC2 2.3714 3.2325 2.3075 9.8724
EPLC-272H GDSC2 2.376 4.4296 1.8653 12.4001
NCI-H358 GDSC2 2.4004 3.6577 2.2081 10.2933
NCI-H3122 GDSC2 2.4081 4.9803 1.6467 13.5958
NCI-H1651 GDSC2 2.4246 3.4385 2.3085 9.6238
Calu-3 GDSC2 2.4324 3.425 2.3212 9.5189
NCI-H2009 GDSC2 2.4423 4.764 1.781 12.6543
NCI-H1792 GDSC2 2.4499 4.4855 1.9156 11.8128
IST-SL2 GDSC2 2.4707 4.6669 1.8539 12.1056
PaCa-3 GDSC2 2.4773 3.7319 2.2629 9.6523
NCI-H810 GDSC2 2.4933 3.2756 2.4298 8.6481
NCI-H2795 GDSC2 2.5278 3.5392 2.3875 8.7264
NCI-H23 GDSC2 2.5356 3.8442 2.2807 9.3056
A-549 GDSC2 2.5389 3.8251 2.2919 9.227
COR-L105 GDSC2 2.5485 3.4884 2.4271 8.4136
NCI-H1703 GDSC2 2.599 3.4736 2.4869 7.8566
HCC78 GDSC2 2.6237 3.5979 2.4701 7.8439
NCI-H69 GDSC2 2.6505 4.3552 2.1767 9.4722
LCLC-97TM1 GDSC2 2.67 3.8737 2.4097 8.002
NCI-H661 GDSC2 2.6931 3.6112 2.5396 7.1512
COR-L88 GDSC2 2.7056 4.0115 2.3871 7.9944
SK-MES-1 GDSC2 2.7184 3.817 2.484 7.3692
NCI-H64 GDSC2 2.7184 3.4171 2.6351 6.5017
SW1271 GDSC2 2.7491 4.0169 2.4291 7.5736
NCI-H2087 GDSC2 2.7808 5.2424 1.8804 10.8301
DMS 53 GDSC2 2.8724 6.4315 1.3783 13.6327
NCI-H2085 GDSC2 2.9169 4.0106 2.601 5.8973
SK-LU-1 GDSC2 2.9346 4.8917 2.1948 8.348
COLO 668 GDSC2 2.9508 4.5878 2.3582 7.2738
NCI-H2731 GDSC2 2.9657 4.4997 2.415 6.8691
Ms-1 GDSC2 2.9863 4.5242 2.4224 6.7522
COR-L279 GDSC2 3.0332 6.8758 1.299 13.6042
NCI-H2342 GDSC2 3.0742 4.3156 2.6061 5.3081
NCI-H2122 GDSC2 3.075 4.5122 2.5103 5.9049
LOU-NH91 GDSC2 3.0788 4.8591 2.3424 6.9469
NCI-H1648 GDSC2 3.1343 4.821 2.4108 6.3381
SBC-3 GDSC2 3.1605 4.7703 2.4592 5.9507
LCLC-103H GDSC2 3.2029 7.3481 1.2088 13.6267
NCI-H1793 GDSC2 3.2406 5.8406 1.9942 8.6429
NCI-H524 GDSC2 3.2496 4.6585 2.5925 4.8329
NCI-H526 GDSC2 3.2736 5.3723 2.2562 6.8891
Lu-99A GDSC2 3.2744 5.3641 2.261 6.8568
COR-L311 GDSC2 3.2923 5.2696 2.3233 6.4093
NCI-H2591 GDSC2 3.2967 8.4763 0.7237 16.1773
HOP-92 GDSC2 3.3 5.3041 2.3125 6.4546
NCI-H1155 GDSC2 3.3425 4.9385 2.5308 4.9497
NCI-H82 GDSC2 3.3688 5.4391 2.3021 6.3216
NCI-H520 GDSC2 3.4097 5.8367 2.1369 7.2506
NCI-H847 GDSC2 3.4168 5.5529 2.2845 6.2976
NCI-H720 GDSC2 3.4172 7.4266 1.3484 12.1473
Lu-135 GDSC2 3.4672 5.3777 2.4125 5.3495
NCI-H522 GDSC2 3.4743 6.5488 1.8337 8.979
HCC827 GDSC2 3.534 6.2063 2.0524 7.4391
SBC-5 GDSC2 3.5389 5.6518 2.3325 5.6616
PC-14 GDSC2 3.5555 5.4424 2.4495 4.8809
DMS 273 GDSC2 3.5744 8.248 1.066 13.3917
CPC-N GDSC2 3.6064 5.8172 2.3027 5.6717
NCI-H1975 GDSC2 3.6328 8.4835 0.9954 13.6413
NCI-H2141 GDSC2 3.6631 8.482 1.0204 13.4103
NCI-H1092 GDSC2 3.6645 6.1513 2.1816 6.2823
NCI-H2722 GDSC2 3.6702 6.7659 1.8809 8.1511
NCI-H1915 GDSC2 3.7735 8.1192 1.2885 11.5182
NCI-H1666 GDSC2 3.7796 10.1416 0.2856 17.151
NCI-H2818 GDSC2 3.7862 7.6053 1.5538 9.8729
NCI-H1355 GDSC2 3.7872 7.1168 1.7969 8.3694
NCI-H2373 GDSC2 3.8444 8.2551 1.276 11.4039
VMRC-LCD GDSC2 3.9113 6.0113 2.4311 4.1394
NCI-H1341 GDSC2 3.9159 5.6607 2.6028 3.0882
NCI-H1694 GDSC2 3.9171 5.6615 2.6032 3.0834
HOP-62 GDSC2 3.9498 11.0081 -0.0112 18.1775
NCI-H441 GDSC2 3.9582 7.1753 1.8964 7.3253
NCI-H1781 GDSC2 3.9897 11.1244 -0.0377 18.1974
NCI-H2023 GDSC2 3.9996 5.7426 2.619 2.8226
NCI-H1838 GDSC2 4.0577 7.8999 1.6134 8.8186
NCI-H1568 GDSC2 4.0745 6.367 2.3717 4.1475
RERF-LC-KJ GDSC2 4.0819 8.7403 1.2171 11.1387
NCI-H2347 GDSC2 4.102 9.6012 0.8063 13.4581
NCI-H1688 GDSC2 4.1202 5.7642 2.6846 2.2199
NCI-H596 GDSC2 4.2509 8.1492 1.6318 8.2449
NCI-H1993 GDSC2 4.2731 7.9317 1.7536 7.4581
NCI-H1650 GDSC2 4.2761 6.4805 2.4493 3.2887
EMC-BAC-2 GDSC2 4.3578 7.8456 1.8544 6.6615
LK-2 GDSC2 4.3936 8.3529 1.6339 7.9055
NCI-H1623 GDSC2 4.4423 9.8453 0.9403 11.8471
NCI-H2369 GDSC2 4.536 6.5526 2.571 2.175
HCC15 GDSC2 4.6529 12.0087 0.0317 16.1362
NCI-H1435 GDSC2 4.6541 12.79 -0.3529 17.952
NCI-H196 GDSC2 4.6636 12.4349 -0.1705 17.0821
NCI-H1563 GDSC2 4.6797 6.5439 2.6523 1.5652
NCI-H1944 GDSC2 4.709 8.7514 1.658 7.0806
NCI-H1573 GDSC2 4.7664 8.8304 1.6585 6.9595
NCI-H2405 GDSC2 4.9312 7.5077 2.3692 2.6583
NCI-H2461 GDSC2 4.9401 8.5569 1.8986 5.236
UMC-11 GDSC2 4.97 14.6228 -1.0207 20.0312
NCI-H513 GDSC2 5.0298 9.6402 1.4476 7.6428
Lu-65 GDSC2 5.0932 7.093 2.6283 1.2192
NCI-H1048 GDSC2 5.1025 6.6246 2.8157 0.5125
NCI-H2595 GDSC2 5.1666 7.1216 2.6509 1.058
LXF 289 GDSC2 5.2032 8.9095 1.8967 4.7842
NCI-H226 GDSC2 5.2849 6.914 2.7822 0.5091
RERF-LC-Sq1 GDSC2 5.2952 9.6223 1.625 6.1344
NCI-H446 GDSC2 5.508 13.237 0.0469 14.0779
NCI-H2228 GDSC2 5.5294 10.3269 1.4436 6.7161
NCI-H322M GDSC2 5.5661 8.1512 2.4222 1.634
NCI-H2170 GDSC2 5.66 8.6181 2.2752 2.1899
SW1573 GDSC2 5.7919 12.0559 0.8018 9.6788
NCI-H2066 GDSC2 5.9201 7.8079 2.7058 0.4092
LC-1/sq GDSC2 6.5108 9.1677 2.4412 0.8386
NCI-H650 GDSC2 6.9405 21.3214 -2.8695 22.0825
⏷ Show the Full List of 131 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 3.0058 4.2441 2.5767 5.726
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OE33 GDSC2 1.057 4.5732 0.4235 26.0901
KYSE-140 GDSC2 1.0802 4.6062 0.4352 25.9252
T.T GDSC2 2.1877 3.5059 2.0294 12.2288
KYSE-150 GDSC2 2.2884 4.3435 1.813 13.0565
TE-6 GDSC2 2.308 5.9969 1.0677 17.4408
TE-9 GDSC2 2.6804 3.3279 2.6202 6.7554
KYSE-410 GDSC2 2.7061 4.1689 2.3174 8.4112
KYSE-270 GDSC2 2.7742 4.1054 2.4148 7.5635
KYSE-70 GDSC2 2.8085 4.0674 2.4665 7.1206
KYSE-450 GDSC2 3.014 3.814 2.7883 4.3951
TE-8 GDSC2 3.3122 4.8125 2.5686 4.7982
KYSE-520 GDSC2 3.3542 6.3866 1.8164 9.429
COLO 680N GDSC2 3.6858 8.9877 0.7863 14.6942
EC-GI-10 GDSC2 3.8192 12.3819 -0.8006 22.1099
KYSE-180 GDSC2 3.9451 7.5504 1.702 8.5553
OE19 GDSC2 4.3103 12.992 -0.7162 20.4295
OE21 GDSC2 4.8348 10.481 0.9114 11.0902
TE-4 GDSC2 4.8945 12.6418 -0.1012 16.1909
TE-5 GDSC2 4.9273 7.0418 2.5681 1.6685
TE-1 GDSC2 5.7953 8.4865 2.3942 1.5315
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Caov-4 GDSC2 1.8098 3.8849 1.4898 16.9138
A2780 GDSC2 2.0019 4.5466 1.4291 16.4659
OAW28 GDSC2 2.2851 4.3976 1.7862 13.2283
TOV-112D GDSC2 2.4486 3.6703 2.2552 9.8182
DOV13 GDSC2 2.6216 4.2874 2.1785 9.5711
OVCAR-3 GDSC2 2.6858 3.8506 2.4359 7.784
OC 314 GDSC2 2.7446 3.7768 2.5282 7.0036
OVKATE GDSC2 2.8233 4.4514 2.3022 8.0693
FU-OV-1 GDSC2 2.8575 3.9226 2.5815 6.2399
OVISE GDSC2 2.8584 4.3528 2.383 7.4458
TYK-nu GDSC2 3.0726 15.1808 -2.8166 30.8425
OVCAR-5 GDSC2 3.394 5.0573 2.5135 4.9128
ES-2 GDSC2 3.4918 5.4343 2.4038 5.3378
TOV-21G GDSC2 3.5719 5.0222 2.6701 3.4547
IGROV-1 GDSC2 3.839 7.3546 1.7186 8.7207
SK-OV-3 GDSC2 3.8618 5.926 2.4378 4.2093
RMG-I GDSC2 4.239 7.1993 2.0841 5.534
OAW42 GDSC2 4.5409 8.7016 1.5677 7.9714
OVCAR-8 GDSC2 4.594 8.7047 1.6027 7.6494
EFO-21 GDSC2 4.7666 9.2542 1.4562 8.1373
OV-90 GDSC2 4.7912 6.744 2.6246 1.5623
OVTOKO GDSC2 5.0544 10.4738 1.0665 9.7447
OV56 GDSC2 5.2131 6.2796 2.9806 0.098
Kuramochi GDSC2 5.6983 8.1844 2.4704 1.311
OVCAR-4 GDSC2 6.2941 18.4563 -1.934 20.4456
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Panc 10.05 GDSC2 2.0229 3.7567 1.7655 14.432
Panc 02.03 GDSC2 2.1083 3.3285 1.9956 12.7729
HPAF-II GDSC2 2.249 3.2596 2.1675 11.1939
PaTu 8988t GDSC2 2.3303 4.7617 1.6698 13.749
Panc 04.03 GDSC2 2.416 3.5625 2.2585 9.9405
KP-1N GDSC2 2.4848 5.1005 1.6656 13.1989
Capan-2 GDSC2 2.559 3.3511 2.4812 8.0675
KP-4 GDSC2 2.6007 3.3924 2.5145 7.6956
PaTu 8902 GDSC2 2.6427 3.5016 2.5248 7.4523
Panc 03.27 GDSC2 2.6687 3.5466 2.5372 7.2692
PSN1 GDSC2 2.6713 3.5642 2.5336 7.2785
YAPC GDSC2 2.7051 3.3297 2.6466 6.4988
DAN-G GDSC2 2.7171 3.7307 2.5182 7.1745
Hs 766T GDSC2 3.1485 4.481 2.5922 5.1507
SUIT-2 GDSC2 3.4119 6.9638 1.5754 10.767
SW1990 GDSC2 3.6441 6.1113 2.1858 6.3081
HuP-T3 GDSC2 3.815 5.9118 2.4114 4.4798
PL4 GDSC2 3.9437 7.864 1.546 9.5136
KP-2 GDSC2 4.2751 6.8915 2.2553 4.4319
CFPAC-1 GDSC2 4.2911 7.7748 1.8423 6.8816
HuP-T4 GDSC2 4.4737 6.8518 2.3995 3.2191
MIA PaCa-2 GDSC2 4.5303 6.8856 2.418 3.0181
Capan-1 GDSC2 4.5912 7.923 1.9737 5.4651
SU.86.86 GDSC2 4.8243 6.7053 2.6576 1.3701
BxPC-3 GDSC2 4.8377 7.9551 2.1136 4.2006
KP-3 GDSC2 4.8835 8.1434 2.0549 4.4514
Panc 08.13 GDSC2 4.9433 8.4179 1.965 4.8537
HPAC GDSC2 5.4035 15.0303 -0.9011 18.5346
AsPC-1 GDSC2 6.243 8.107 2.7204 0.2678
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC2 2.8873 4.3969 2.39 7.299
MSTO-211H GDSC2 2.9861 4.1731 2.592 5.7006
MPP 89 GDSC2 3.7721 8.573 1.0615 12.87
IST-Mes1 GDSC2 4.061 12.0689 -0.452 19.9409
NCI-H2052 GDSC2 4.8565 9.4209 1.437 8.0588
NCI-H28 GDSC2 5.7162 7.8138 2.6221 0.75
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 1.7953 4.6514 1.1698 18.8123
VCaP GDSC2 2.2808 3.5191 2.1263 11.2758
22Rv1 GDSC2 2.299 3.6202 2.112 11.2763
PC-3 GDSC2 2.5513 3.6938 2.3565 8.8017
DU145 GDSC2 4.5928 7.1787 2.3215 3.4527
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 3.8271 6.1393 2.3088 5.0863
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-MEL1 GDSC2 0.917 1.8534 0.914 24.1487
HMV-II GDSC2 1.7804 3.3213 1.6397 16.2107
HT-144 GDSC2 1.948 3.4213 1.7942 14.6033
COLO 792 GDSC2 2.076 3.2708 1.9759 13.0284
LOX-IMVI GDSC2 2.0955 3.4433 1.9485 13.0891
WM35 GDSC2 2.109 4.4569 1.5786 15.1573
GAK GDSC2 2.2036 3.266 2.1163 11.6805
SH-4 GDSC2 2.2676 3.5675 2.096 11.5033
WM115 GDSC2 2.3782 3.1789 2.3272 9.7353
COLO 679 GDSC2 2.4097 3.4011 2.3037 9.7173
COLO 829 GDSC2 2.4139 3.3977 2.3093 9.668
CHL-1 GDSC2 2.4484 3.3834 2.3512 9.2814
IGR-1 GDSC2 2.4754 3.5642 2.3221 9.3233
A-375 GDSC2 2.5304 3.5623 2.3823 8.7442
G-361 GDSC2 2.5762 3.5768 2.4266 8.2951
UACC-62 GDSC2 2.6616 3.2575 2.6178 6.8554
UACC-257 GDSC2 2.8782 3.8243 2.6462 5.7716
MeWo GDSC2 2.9199 3.9916 2.6128 5.814
SK-MEL-24 GDSC2 2.9405 3.997 2.6307 5.6283
SK-MEL-2 GDSC2 2.9733 4.1159 2.6069 5.6542
M14 GDSC2 3.0224 7.0317 1.2118 14.1657
A2058 GDSC2 3.1533 4.8396 2.4183 6.2311
WT2-iPS GDSC2 3.1712 4.2246 2.7395 4.1505
WM1552C GDSC2 3.2269 4.6851 2.5596 5.1105
Mel JuSo GDSC2 3.2686 4.5628 2.6566 4.3703
A101D GDSC2 3.2708 5.4954 2.1924 7.3012
WM793 GDSC2 3.2911 4.8448 2.5346 5.0752
SK-MEL-1 GDSC2 3.4172 4.8626 2.6295 4.1151
IGR-37 GDSC2 3.718 5.6678 2.4605 4.4048
WM278 GDSC2 4.0143 8.8289 1.122 11.8718
RPMI-7951 GDSC2 4.632 7.1259 2.369 3.1212
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW982 GDSC2 1.8498 5.533 0.8358 20.5134
EW-8 GDSC2 2.0749 3.4092 1.9362 13.2499
KYM-1 GDSC2 2.0814 2.9881 2.0424 12.649
Hs 633.T GDSC2 2.3592 3.4829 2.2233 10.388
MFH-ino GDSC2 2.4103 3.7779 2.1737 10.4475
SW872 GDSC2 2.452 3.2852 2.3823 9.0959
SW684 GDSC2 2.6697 3.2294 2.6331 6.7357
RKN GDSC2 2.79 3.8192 2.5576 6.6473
SK-UT-1 GDSC2 2.9569 4.0962 2.6003 5.7538
Rh30 GDSC2 3.3174 4.7179 2.6202 4.4563
G-401 GDSC2 3.6151 8.4224 1.0117 13.5954
HT-1080 GDSC2 3.7913 6.0072 2.3476 4.9309
G-402 GDSC2 3.8101 6.5845 2.0775 6.5652
Rh41 GDSC2 4.0014 20.1611 -4.5384 32.237
SK-LMS-1 GDSC2 4.0462 9.8258 0.6521 14.4625
MES-SA GDSC2 4.2502 11.4276 0.0143 17.2465
RD GDSC2 4.5477 6.5216 2.5912 2.0512
GCT GDSC2 4.654 8.9938 1.5047 8.0961
VA-ES-BJ GDSC2 4.6819 7.3655 2.2896 3.4796
A-204 GDSC2 4.9355 8.5895 1.8806 5.3471
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC2 1.1825 2.453 1.1546 21.6107
Fu97 GDSC2 1.9837 3.8123 1.7033 14.9538
ECC10 GDSC2 2.1078 3.4287 1.9663 12.936
NCI-N87 GDSC2 2.3137 7.4846 0.3504 21.4468
MKN28 GDSC2 2.3848 4.3116 1.9263 12.0019
AGS GDSC2 2.4648 3.6402 2.2837 9.5862
RF-48 GDSC2 2.4766 3.4853 2.3501 9.1616
RERF-GC-1B GDSC2 2.4843 4.9024 1.7582 12.6367
NUGC-3 GDSC2 2.5351 4.3793 2.0496 10.6789
Hs 746.T GDSC2 2.7331 3.6459 2.569 6.8131
OCUM-1 GDSC2 2.9212 4.4362 2.4035 7.0953
SK-GT-2 GDSC2 2.9624 5.1187 2.1088 8.7939
MKN1 GDSC2 3.0712 4.7524 2.3883 6.6833
HGC-27 GDSC2 3.1058 4.7793 2.4061 6.4593
MKN45 GDSC2 3.5516 5.1345 2.5992 3.9504
SNU-1 GDSC2 3.6482 5.4678 2.5072 4.2838
MKN7 GDSC2 3.8529 5.9453 2.4221 4.326
GCIY GDSC2 3.8662 5.7691 2.5169 3.7152
KATO III GDSC2 3.9242 7.5636 1.6798 8.7441
SNU-16 GDSC2 3.9615 5.4546 2.7298 2.2466
SNU-5 GDSC2 4.0736 6.1597 2.47 3.56
TGBC11TKB GDSC2 4.1449 6.2983 2.451 3.5301
IM95 GDSC2 4.5326 9.1093 1.3646 9.1868
23132/87 GDSC2 5.5886 8.0178 2.4866 1.3432
NUGC-4 GDSC2 5.8967 7.6957 2.7369 0.3466
SNG-M GDSC2 4.4461 6.3787 2.5976 2.169
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-62 GDSC2 2.1453 3.3362 2.0339 12.3951
HTC-C3 GDSC2 2.1834 4.4393 1.6631 14.3614
8505C GDSC2 2.2324 3.3251 2.132 11.463
FTC-133 GDSC2 2.4538 12.9136 -2.2152 31.0757
WRO GDSC2 2.5521 4.7552 1.8939 11.5595
8305C GDSC2 3.0462 6.5684 1.4635 12.5552
BHT-101 GDSC2 3.1955 7.2587 1.2473 13.4171
IHH-4 GDSC2 3.3012 4.9529 2.4891 5.3332
CGTH-W-1 GDSC2 3.3978 4.7765 2.6569 3.9953
B-CPAP GDSC2 3.4256 5.5729 2.2816 6.2914
ASH-3 GDSC2 3.6942 5.5595 2.4962 4.2399
K5 GDSC2 4.424 6.3391 2.6027 2.1755
TT2609-C02 GDSC2 4.59 6.5129 2.6182 1.8523
TT GDSC2 5.3594 7.0589 2.7585 0.538
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SAS GDSC2 1.1947 4.3352 0.6621 24.2073
HO-1-u-1 GDSC2 1.2616 4.7516 0.569 24.4171
JHU-022 GDSC2 1.3007 3.0173 1.1911 20.8521
PCI-30 GDSC2 1.782 5.6781 0.7016 21.5347
HO-1-N-1 GDSC2 1.8952 4.1918 1.464 16.6996
HSC-4 GDSC2 2.1785 3.2522 2.0924 11.9253
BICR 22 GDSC2 2.2018 5.0097 1.4278 15.6905
HSC-2 GDSC2 2.2193 3.266 2.1334 11.5156
BICR 78 GDSC2 2.3208 4.4698 1.7912 13.0583
SCC-15 GDSC2 2.3413 3.7906 2.0952 11.1904
CAL-33 GDSC2 2.3526 3.6673 2.153 10.8118
Ca9-22 GDSC2 2.6429 3.7322 2.4391 7.9409
NCI-H3118 GDSC2 2.8303 3.9723 2.5315 6.6453
FaDu GDSC2 2.8783 4.083 2.5291 6.4783
SAT [Human HNSCC] GDSC2 3.0784 7.9478 0.8031 16.3956
Detroit 562 GDSC2 3.1006 5.0848 2.2499 7.4598
SCC-4 GDSC2 3.1309 5.2376 2.2006 7.6751
BICR 10 GDSC2 3.1541 6.0808 1.8003 10.1251
SKN-3 GDSC2 3.5275 5.7841 2.2577 6.163
HSC-3 GDSC2 3.7017 6.6383 1.9686 7.5204
CAL-27 GDSC2 3.814 6.4372 2.153 6.086
DOK GDSC2 3.8564 7.4244 1.6973 8.8082
SCC-9 GDSC2 4.0164 10.3994 0.3439 16.1966
UPCI-SCC-090 GDSC2 4.1011 7.235 1.9706 6.531
OSC-20 GDSC2 4.7029 8.1624 1.9331 5.4839
LB771-HNC GDSC2 5.2326 11.6295 0.6325 11.7192
BB49-HNC GDSC2 6.0695 8.5779 2.4803 0.9883
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC2 1.2188 2.9927 1.1076 21.6817
647V GDSC2 2.3108 3.4056 2.1945 10.7647
KU-19-19 GDSC2 2.5592 3.9829 2.2481 9.4009
HT-1197 GDSC2 2.5891 6.7608 0.9592 17.0894
UM-UC-3 GDSC2 2.6943 3.4822 2.5873 6.875
HT-1376 GDSC2 2.9391 3.9314 2.6596 5.458
RT-112 GDSC2 3.5897 5.608 2.3937 5.1432
TCCSUP GDSC2 3.6992 5.6556 2.4526 4.4997
SW1710 GDSC2 4.2113 10.125 0.6301 14.1513
CAL-29 GDSC2 4.2577 7.187 2.1027 5.3816
639V GDSC2 4.2695 5.6876 2.8042 1.3427
5637 GDSC2 4.3701 7.5265 2.0159 5.6654
RT-4 GDSC2 5.09 7.3755 2.51 1.7515
SW780 GDSC2 5.3799 7.9782 2.4028 1.9183
J82 GDSC2 5.6263 7.8863 2.5557 1.0437
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC2 1.3765 2.7972 1.3157 19.8348
KGN GDSC2 2.0698 6.2386 0.7229 20.3066
OVMIU GDSC2 2.1289 6.4128 0.6967 20.2331
C-33 A GDSC2 2.1577 3.55 1.9825 12.6225
NEC8 GDSC2 2.274 3.3963 2.1571 11.1358
SKN GDSC2 2.3228 7.0732 0.5601 20.2856
ME-180 GDSC2 2.4797 3.422 2.3737 9.0166
SW756 GDSC2 2.5257 3.501 2.3982 8.6757
NT2-D1 GDSC2 2.5284 3.5733 2.3762 8.7876
DoTc2 4510 GDSC2 2.5771 3.614 2.4141 8.3629
SKG-IIIa GDSC2 2.7077 3.3716 2.6374 6.5369
LB831-BLC GDSC2 2.9472 7.849 0.739 17.1751
NCC-IT GDSC2 2.9792 4.8734 2.2449 7.8858
Ca Ski GDSC2 3.1084 5.0572 2.2705 7.3047
DSH1 GDSC2 3.2827 6.7248 1.5877 11.067
PEO1 GDSC2 3.2839 5.6571 2.1225 7.704
PA-1 GDSC2 3.6082 7.3836 1.5244 10.5314
BPH-1 GDSC2 3.9368 11.0387 -0.0368 18.3378
C-4-I GDSC2 3.9703 8.6224 1.1907 11.5814
SiHa GDSC2 4.0477 6.2178 2.425 3.8829
MS751 GDSC2 4.1084 7.0264 2.0772 5.8631
CAL-39 GDSC2 4.1221 6.0429 2.5565 2.9541
HeLa GDSC2 4.3879 9.3867 1.1255 10.9187
PWR-1E GDSC2 4.583 10.653 0.6468 13.1322
OVCA420 GDSC2 4.6149 13.6233 -0.7949 19.9802
HT-3 GDSC2 4.7202 7.8346 2.0971 4.5034
SiSo GDSC2 5.2473 8.0354 2.3103 2.5238
HEC-1 GDSC2 5.6182 7.1791 2.8157 0.2759
HEY GDSC2 5.6745 8.6529 2.2679 2.2071
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug

References

1 A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo. Mol Cancer Ther. 2014 Mar;13(3):565-75.