Details of the Drug

General Information of Drug (ID: DM59UDI)

Drug Name
AZ-23
Synonyms AZ-64; Trk inhibitors (cancer); Trk inhibitors (cancer), AstraZeneca
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C17H19ClFN7O
Canonical SMILES
CC(C)OC1=NNC(=C1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=C3)F
InChI
InChI=1S/C17H19ClFN7O/c1-9(2)27-15-6-14(25-26-15)23-16-12(18)8-21-17(24-16)22-10(3)13-5-4-11(19)7-20-13/h4-10H,1-3H3,(H3,21,22,23,24,25,26)/t10-/m0/s1
InChIKey
LBVKEEFIPBQIMD-JTQLQIEISA-N
Cross-matching ID
PubChem CID
16097523
ChEBI ID
CHEMBL457614
CAS Number
915720-21-7
TTD ID
D0O8AR
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.