Details of the Drug

General Information of Drug (ID: DM5G3B0)

Drug Name

PF-04171327

Synonyms

Fosdagrocorat; UNII-HPI19004QS; 1044535-58-1; PF-04171327; HPI19004QS; 2-Phenanthrenecarboxamide, 4b,5,6,7,8,8a,9,10-octahydro-N-(2-methyl-3-pyridinyl)-4b-(phenylmethyl)-7-(phosphonooxy)-7-(trifluoromethyl)-, (4bS,7R,8aR)-;2-Phenanthrenecarboxamide, 4b,5,6,7,8,8a,9,10-octahydro-N-(2-methyl-3-pyridinyl)-4b-(phenylmethyl)-7-(phosphonooxy)-7-(trifluoromethyl)-, (4bS,7R,8aR)-; Fosdagrocorat [USAN:INN]; PF 04171327; Fosdagrocorat (USAN/INN); SCHEMBL1707427; GTPL9649; US8901310, Example 2; CHEMBL3137316; BDBM140010; SB17317

Indication

Disease Entry	ICD 11	Status	REF
Rheumatoid arthritis	FA20	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C29H30F3N2O5P
Canonical SMILES: CC1=C(C=CC=N1)NC(=O)C2=CC3=C(C=C2)C4(CCC(CC4CC3)(C(F)(F)F)OP(=O)(O)O)CC5=CC=CC=C5
InChI: 1S/C29H30F3N2O5P/c1-19-25(8-5-15-33-19)34-26(35)22-10-12-24-21(16-22)9-11-23-18-28(29(30,31)32,39-40(36,37)38)14-13-27(23,24)17-20-6-3-2-4-7-20/h2-8,10,12,15-16,23H,9,11,13-14,17-18H2,1H3,(H,34,35)(H2,36,37,38)/t23-,27+,28-/m1/s1
InChIKey: BVXLAHSJXXSWFF-KEKPKEOLSA-N

Cross-matching ID

PubChem CID: 24872952
CAS Number: 1044535-58-1
UNII: HPI19004QS
DrugBank ID: DB12198
TTD ID: D01PLR

References

1	ClinicalTrials.gov (NCT00938587) A Study Of PF-04171327 In The Treatment Of The Signs And Symptoms Of Rheumatoid Arthritis. U.S. National Institutes of Health.