Details of the Drug

General Information of Drug (ID: DM5I2HL)

Drug Name
GSK269962A
Synonyms GSK-269962A; GSK269962; GSK 269962; GSK-269962; aminofurazanyl-azabenzimidazole 6n
Indication
Disease Entry ICD 11 Status REF
Inflammation 1A00-CA43.1 Clinical trial [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 570.6
Logarithm of the Partition Coefficient (xlogp) 2.2
Rotatable Bond Count (rotbonds) 10
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 11
Chemical Identifiers
Formula
C29H30N8O5
IUPAC Name
N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
Canonical SMILES
CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
InChI
InChI=1S/C29H30N8O5/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39-14-11-36/h3-9,16-18H,2,10-15H2,1H3,(H2,30,35)(H,32,38)
InChIKey
YOVNFNXUCOWYSG-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
16095342
CAS Number
925213-63-4
UNII
F89KMM7TE2
DrugBank ID
DB17030
TTD ID
D02ZQS
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Rho-associated protein kinase 1 (ROCK1) TTZN7RP ROCK1_HUMAN Inhibitor [1]
Rho-associated protein kinase 2 (ROCK2) TTGWKQJ ROCK2_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Inflammation
ICD Disease Classification 1A00-CA43.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Rho-associated protein kinase 2 (ROCK2) DTT ROCK2 1.55E-01 0.12 0.71
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 2.552 6.0979 0.6221 12.4733
HOS GDSC1 0.0349 5.2211 -1.2981 35.5674
ES8 GDSC1 0.2477 5.0122 -0.9884 29.9117
CADO-ES1 GDSC1 1.0282 5.7897 -0.5805 26.8511
ES6 GDSC1 1.3724 12.2055 -3.4319 33.7242
CAL-72 GDSC1 1.545 16.4343 -5.3917 38.6389
G-292 clone A141B1 GDSC1 1.7245 17.1531 -5.5972 38.4118
ES7 GDSC1 1.8128 5.8627 0.1112 17.0151
CHSA0108 GDSC1; GDSC2 1.8265 10.1022 -1.383 30.6498
CHSA8926 GDSC1 2.1885 16.7313 -4.9943 36.1821
EW-16 GDSC1 2.3398 4.275 1.3603 6.6839
TC-71 GDSC1 2.4785 10.3037 -1.5392 23.6527
ES1 GDSC1 2.4944 6.8417 0.2041 14.0889
ES4 GDSC1 2.5527 6.9947 0.175 14.092
EW-22 GDSC1 2.5868 5.8022 0.7973 9.8366
EW-7 GDSC1 2.5963 9.471 -1.0266 22.7479
SaOS-2 GDSC1 2.599 15.5435 -4.0594 33.1734
SJSA-1 GDSC1 2.8161 10.2624 -1.2444 21.2358
EW-13 GDSC1 2.9469 8.4247 -0.2255 15.3682
MG-63 GDSC1 3.1363 9.1773 -0.453 17.742
SK-ES-1 GDSC1 3.1896 4.9259 1.6523 2.5273
MHH-ES-1 GDSC1; GDSC2 3.2064 7.887 0.9424 15.1963
A-673 GDSC1 3.2932 7.7379 0.3746 11.88
CHSA0011 GDSC1; GDSC2 3.3009 13.9153 -1.9922 27.8836
NY GDSC1 3.3303 6.8253 0.8452 8.3929
EW-11 GDSC1 3.3991 9.3169 -0.3235 14.6516
NOS-1 [Human HNSCC] GDSC1 3.4486 7.4332 0.6335 8.5884
SK-PN-DW GDSC1 3.4661 9.6522 -0.4389 15.1278
EW-12 GDSC1; GDSC2 3.5843 8.944 0.7265 15.2707
EW-3 GDSC1 3.6815 6.4133 1.2676 3.9885
ES5 GDSC1; GDSC2 3.736 9.6275 0.5072 16.0493
EW-24 GDSC1 3.8907 9.9225 -0.2636 13.0134
U2OS GDSC1; GDSC2 3.9694 11.8602 -0.4204 20.0484
EW-18 GDSC1 4.1447 11.8897 -1.041 16.5391
U-CH2 GDSC2 4.2211 7.6318 1.8626 6.916
HuO-3N1 GDSC1 4.3644 12.9943 -1.4227 19.2394
HuO9 GDSC1 4.3823 9.6227 0.2126 10.0503
CAL-78 GDSC1 4.6011 14.3183 -1.8992 20.7274
EW-1 GDSC1 4.8332 6.735 1.6985 0.5144
H-EMC-SS GDSC1 5.104 10.4174 0.2904 7.1836
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 166 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 3.1362 11.201 -0.7734 23.9336
SR GDSC1 -4.6755 -1.2012 -4.7129 73.5962
MV4-11 GDSC1 -2.6175 1.6483 -2.9008 54.0017
SUP-B8 GDSC1; GDSC2 -2.4883 0.2361 -2.5109 57.9913
MY-M12 GDSC1; GDSC2 -2.4246 2.2821 -2.6991 56.1261
BE-13 GDSC1 -2.2844 3.9754 -3.237 50.7778
697 GDSC1 -1.8796 2.273 -2.2501 47.2471
RCH-ACV GDSC1; GDSC2 -1.3663 4.9882 -2.3299 47.9428
SU-DHL-8 GDSC1 -1.1189 2.8268 -1.5823 40.0884
SU-DHL-5 GDSC1 -1.0709 6.6524 -3.0616 46.1014
OCI-Ly7 GDSC1; GDSC2 -0.8888 2.0041 -0.9921 42.6176
EM-2 GDSC1 -0.4672 12.5531 -5.2704 43.1515
SUP-B15 GDSC1 -0.3848 5.5262 -2.3296 32.5453
Kasumi-1 GDSC1; GDSC2 -0.2904 3.7939 -0.7586 38.0225
Ramos.2G6.4C10 GDSC1 -0.2245 6.8089 -2.2837 37.0958
QIMR-WIL GDSC1; GDSC2 -0.2004 5.9482 -1.4592 39.5831
Loucy GDSC1 -0.1846 2.8027 -0.5584 29.9426
P30/OHK GDSC1 -0.0549 5.07 -1.3224 32.9238
GDM-1 GDSC1 -0.0171 9.935 -3.5745 39.128
CRO-AP2 GDSC1; GDSC2 0.0617 5.7998 -1.1228 37.2846
DoHH2 GDSC1; GDSC2 0.4005 5.3364 -0.5765 33.6844
OCI-M1 GDSC1 0.4066 2.2801 0.243 22.2313
MOLT-16 GDSC1 0.5466 4.6826 -0.5375 26.1583
JeKo-1 GDSC1; GDSC2 0.5958 5.7787 -0.5562 32.7603
BC-1 GDSC1 0.6919 7.4062 -1.68 30.8687
ALL-SIL GDSC1 0.6964 9.1945 -2.548 33.8075
MOLT-13 GDSC1 0.7632 5.443 -0.6723 25.9047
BONNA-12 GDSC2 0.7861 10.5859 -2.5919 37.7815
SU-DHL-16 GDSC1; GDSC2 0.973 4.2936 0.4402 26.2918
OCI-AML-5 GDSC1 1.0054 10.8686 -3.0927 34.1411
Karpas-231 GDSC1 1.0354 9.5251 -2.4009 32.0291
SU-DHL-4 GDSC1; GDSC2 1.0873 3.8727 0.7134 24.3255
TALL-1 [Human adult T-ALL] GDSC2 1.0968 5.1473 0.2325 26.8938
EHEB GDSC1 1.1241 23.3466 -9.2045 43.2041
NALM-6 GDSC1 1.1597 6.8938 -0.9925 25.8644
Jurkat GDSC1 1.1867 8.9171 -1.9637 32.3048
ML-2 GDSC1 1.2259 15.7366 -5.3194 37.8305
MOLM-16 GDSC1; GDSC2 1.3424 4.3726 0.8054 22.7775
Daudi GDSC1 1.3803 6.119 -0.409 21.8438
SUP-M2 GDSC1 1.3945 5.8175 -0.2483 20.8419
BC-3 GDSC1; GDSC2 1.3975 4.9129 0.6449 23.3436
SIG-M5 GDSC1; GDSC2 1.4382 3.0574 1.3319 19.3876
PL-21 GDSC1; GDSC2 1.4642 11.6697 -2.4859 34.985
Ku812 GDSC1 1.4978 8.9874 -1.7203 27.8135
RPMI-8402 GDSC1 1.5292 9.1197 -1.7583 27.8508
BL-41 GDSC1 1.5333 9.4719 -1.9298 28.5093
CMK GDSC1 1.5453 13.362 -3.858 36.0347
MOLM-13 GDSC1 1.5828 11.9175 -3.105 32.1677
MC116 GDSC1; GDSC2 1.64 7.0158 -0.0628 25.9827
CCRF-CEM GDSC1 1.6608 7.2597 -0.7175 22.4824
ST486 GDSC1 1.7212 9.0219 -1.541 26.2428
HH [Human lymphoma] GDSC1 1.7223 4.6648 0.6197 13.9868
MHH-PREB-1 GDSC1 1.7819 7.3846 -0.6724 21.7885
KOPN-8 GDSC1 1.7969 6.0294 0.0143 19.7023
L-540 GDSC1 1.8681 9.3139 -1.5591 25.7961
MOLT-4 GDSC1 1.8939 3.8035 1.2 9.3603
BV-173 GDSC1 1.9496 11.652 -2.6569 29.6175
MHH-CALL-4 GDSC2 1.9496 10.1001 -1.2693 29.8198
OCI-AML-3 GDSC1 2.0547 4.1312 1.186 8.8668
DND-41 GDSC1 2.0722 4.531 1.0029 10.0786
P31/FUJ GDSC1 2.0728 7.8798 -0.6673 20.7192
P32/ISH GDSC1 2.0781 4.4759 1.0355 9.8312
SU-DHL-6 GDSC1 2.164 5.1199 0.7893 11.2429
SUP-T1 GDSC1 2.1954 3.2516 1.7478 4.4513
TUR GDSC1 2.2062 3.9561 1.4065 6.7997
Mono-Mac-6 GDSC1 2.209 5.6782 0.5488 12.7359
KG-1 GDSC1 2.2294 6.9492 -0.0693 16.6887
JJN-3 GDSC1 2.2745 4.9835 0.9514 9.7522
NK-92MI GDSC1; GDSC2 2.2826 9.6481 -0.7442 26.5956
Raji GDSC1 2.353 3.7313 1.643 4.6605
Karpas-620 GDSC1 2.3818 21.748 -7.3412 38.8647
Farage GDSC1; GDSC2 2.4256 6.5344 0.9189 17.832
AMO1 GDSC1 2.4695 8.1507 -0.4704 18.282
HAL-01 GDSC1 2.4717 10.1618 -1.4739 23.3836
LC4-1 GDSC1 2.4792 5.5926 0.8158 10.0388
U-698-M GDSC1 2.4801 6.8725 0.1771 14.3081
RPMI-8866 GDSC1 2.5003 6.3689 0.4452 12.4875
NCI-H929 GDSC1 2.5023 6.6208 0.3209 14.8441
PF-382 GDSC1 2.5089 7.9726 -0.3492 17.4538
DB GDSC1 2.5214 11.645 -2.1744 26.1072
NKM-1 GDSC1 2.5306 5.4894 0.9086 9.2407
CA46 GDSC1 2.56 11.1279 -1.8842 24.8539
MEG-01 GDSC1 2.6003 5.0559 1.1794 7.1541
IM-9 GDSC1 2.6027 3.9894 1.7091 3.4725
CESS GDSC1 2.6349 6.7421 0.3669 12.5886
JVM-3 GDSC1 2.7101 6.7268 0.4341 11.9174
SU-DHL-10 GDSC1 2.7139 5.0374 1.2754 6.9335
Reh GDSC1 2.724 10.6778 -1.5258 22.8182
Karpas-45 GDSC1 2.7276 9.7539 -1.0616 20.6182
GR-ST GDSC1 2.8174 15.1898 -3.7039 30.0446
HC-1 GDSC1 2.8444 4.501 1.6311 3.3971
NOMO-1 GDSC1 2.8463 9.5495 -0.8647 19.2456
ATN-1 GDSC1 2.8757 6.8396 0.5063 10.9528
KE-37 GDSC1 2.8763 9.595 -0.8636 19.1484
A4/Fukuda GDSC1 2.9005 9.3 -0.6974 18.1913
HDLM-2 GDSC1 2.9255 7.6508 0.1422 13.1714
P12-Ichikawa GDSC1 2.9414 6.3126 0.8164 9.7404
KCL-22 GDSC1 2.9468 5.0676 1.4285 4.5138
SCC-3 GDSC1 2.9649 10.3778 -1.9205 17.8486
SK-MM-2 GDSC1 3.0138 6.899 0.5813 10.0664
A3/Kawakami GDSC1 3.0197 16.8314 -4.3598 31.1112
ARH-77 GDSC1 3.0346 5.3146 1.3698 4.6987
EoL-1 GDSC1 3.0418 18.0213 -4.9362 32.297
MN-60 GDSC1 3.0604 6.7789 0.675 9.3154
OCI-AML-2 GDSC1 3.0806 9.3764 -0.5947 17.0918
EJM GDSC1 3.0942 6.1982 0.9836 7.153
KMOE-2 GDSC1 3.1032 5.3869 1.3815 4.4606
LP-1 GDSC1; GDSC2 3.1204 4.6375 2.4894 5.8672
CTB-1 GDSC1; GDSC2 3.1262 6.6345 1.4999 12.0416
KMS-11 GDSC1; GDSC2 3.1325 7.3361 1.1549 14.1657
NU-DUL-1 GDSC1; GDSC2 3.2002 5.1594 2.2999 6.81
SU-DHL-1 GDSC1; GDSC2 3.254 8.2828 0.7847 15.9093
Sc-1 GDSC1 3.2553 9.2328 -0.3898 15.4346
CML-T1 GDSC1 3.2836 7.7506 0.3614 12.0009
NB4 GDSC1; GDSC2 3.2884 7.9207 0.9946 14.5958
L-1236 GDSC1 3.2898 6.1535 1.1403 5.6299
CTV-1 GDSC1 3.3096 6.6582 0.9115 7.1
YT GDSC1 3.3336 6.3393 1.0809 5.9213
RS4;11 GDSC1 3.351 8.3431 0.12 12.1191
Namalwa GDSC1 3.3566 11.8314 -1.6005 21.2765
OCI-Ly19 GDSC1; GDSC2 3.3673 8.7404 0.6504 16.3256
ROS-50 GDSC1; GDSC2 3.4376 4.8803 2.6369 3.9984
Jiyoye GDSC1 3.4429 6.5666 1.0453 5.906
KMS-12-BM GDSC1 3.5384 4.7517 0.9342 0.1235
Hs 445 GDSC1 3.5536 8.3418 0.2665 10.6745
ALL-PO GDSC1 3.5838 11.7089 -1.3659 19.5797
RC-K8 GDSC1 3.6176 10.137 -0.5654 15.423
H9 GDSC1 3.6299 8.6755 0.1582 11.155
L-363 GDSC1 3.6399 20.4739 -5.6804 32.3184
DG-75 GDSC1 3.6834 10.9008 -0.8925 16.988
THP-1 GDSC1; GDSC2 3.699 6.1759 2.1957 6.084
ME1 GDSC1 3.7272 4.9652 1.9086 0.4967
RPMI-8226 GDSC1 3.7361 8.904 0.1219 11.1114
GA-10 GDSC1 3.7991 14.1694 -2.4203 23.3749
SKM-1 GDSC1; GDSC2 3.8033 9.0738 0.8366 14.0387
L-428 GDSC1 3.9246 5.6393 1.7325 1.0463
MOLP-8 GDSC1 3.9374 16.0406 -3.242 25.787
DEL GDSC1 3.9465 10.4889 -0.4996 14.2029
Granta-519 GDSC1 3.9644 6.8331 1.2435 3.6247
WSU-DLCL2 GDSC1 3.9795 5.3294 1.8757 0.4449
JVM-2 GDSC1 4.0959 16.76 -3.4773 26.104
WSU-NHL GDSC1 4.1223 14.5218 -2.3503 22.2833
LAMA-84 GDSC1 4.1809 11.0206 -0.5924 14.1252
RL GDSC1; GDSC2 4.2357 12.3259 -0.443 19.3828
MLMA GDSC1 4.2933 10.644 -0.3329 12.4271
Karpas-299 GDSC1 4.4162 10.5838 -0.221 11.5119
HT GDSC1; GDSC2 4.4282 14.4037 -1.3262 22.5029
TK [Human B-cell lymphoma] GDSC1 4.4393 14.0976 -1.9081 19.7473
K-562 GDSC1 4.4825 12.4196 -1.0594 15.7998
VAL GDSC1 4.53 16.7482 -3.1439 24.0412
RPMI-6666 GDSC1 4.5301 11.3853 -0.5278 12.9461
MHH-CALL-2 GDSC1 4.5481 6.2926 1.7479 0.5836
Karpas-1106P GDSC1 4.5814 6.3279 1.7482 0.5626
KY821 GDSC1 4.6181 6.4507 1.7176 0.5726
WIL2 NS GDSC1 4.859 13.4647 -1.303 16.0837
Karpas-422 GDSC1 5.1062 12.2846 -0.5741 11.922
SUP-HD1 GDSC1 5.3595 14.3679 -1.3964 15.4015
OPM-2 GDSC1 5.5108 16.3418 -2.2413 18.6295
HL-60 GDSC1 5.6431 13.8011 -0.9422 12.6725
BALL-1 GDSC1 5.8563 15.4629 -1.588 15.2147
KM-H2 GDSC1 5.9844 17.0099 -2.2396 17.6316
JURL-MK1 GDSC1 6.0447 20.2484 -3.7602 22.6479
VL51 GDSC1 6.1528 18.6553 -2.9148 19.7516
EB2 GDSC1 6.2689 16.3268 -1.7277 14.9932
U266B1 GDSC1 6.5194 14.6742 -0.8058 10.3728
HEL GDSC1; GDSC2 6.6213 16.6632 -0.8397 15.6722
⏷ Show the Full List of 166 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 2.393 5.226 0.9287 10.7027
OACP4 C GDSC1 2.8156 14.1624 -3.1921 30.3374
KYAE-1 GDSC1 3.014 6.2699 0.8908 8.9614
SK-GT-4 GDSC1 3.3143 6.9441 0.7765 8.9401
FLO-1 GDSC1 3.3368 6.7551 0.8835 8.0945
TE-12 GDSC1; GDSC2 3.5101 6.7799 1.7472 9.3879
ESO-51 GDSC1 3.6409 7.8407 0.5694 9.5304
KYSE-220 GDSC1 3.6747 8.8466 0.1067 12.5897
OACM5.1 C GDSC1 3.8014 6.754 1.1838 4.8076
HCE-4 GDSC1; GDSC2 3.9528 11.8159 -0.4114 20.0535
KYSE-50 GDSC1 4.5056 6.2847 1.7339 0.6602
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 2.6457 4.6288 1.426 5.3121
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-ME-N GDSC1 -4.1774 6.2028 -6.1096 59.7302
SJNB-6 GDSC1; GDSC2 0.3626 6.3627 -1.0487 35.5533
CHP-212 GDSC1 0.4143 3.0282 0.012 26.4824
Kelly GDSC1 0.796 5.6883 -0.7561 26.2032
IMR-5 GDSC1 0.9965 3.6973 0.3586 18.6993
SK-N-SH GDSC1 1.0255 5.6162 -0.5 26.4076
SJNB-17 GDSC1; GDSC2 1.3373 6.9837 -0.3443 28.4945
SK-N-DZ GDSC1 1.375 4.7753 0.2382 17.8771
KP-N-YS GDSC1; GDSC2 1.554 5.748 0.4405 23.7937
MHH-NB-11 GDSC1; GDSC2 1.6902 9.4189 -1.1742 30.3615
NB1 GDSC1 2.0881 6.4292 0.0703 16.2955
TGW GDSC1 2.1369 7.9358 -0.6407 20.3513
SJNB-13 GDSC1 2.1629 7.3743 -0.338 18.5387
SJNB-12 GDSC1 2.2036 10.8893 -2.0607 26.692
SJNB-10 GDSC1 2.2061 6.8357 -0.0322 16.5369
SJNB-14 GDSC1 2.3066 6.0444 0.4479 13.0907
SK-N-BE(2)-M17 GDSC1 2.5952 7.0811 0.1661 14.0163
SK-N-FI GDSC1 2.5977 4.963 1.2236 6.8544
KP-N-YN GDSC1 2.7197 6.3605 0.6238 10.621
NH-12 GDSC1 2.7988 5.1924 1.2622 6.026
SJNB-7 GDSC1 3.1632 7.0131 0.6351 9.3058
SK-N-MC-IXC GDSC1; GDSC2 3.1983 6.6709 1.5434 11.5941
NB69 GDSC1 3.2451 6.2782 1.0503 6.333
SiMa GDSC1 3.3329 13.7562 -2.5761 25.1877
SK-N-AS GDSC1 3.364 5.2462 1.6099 2.7779
GOTO GDSC1 3.6906 9.1895 -0.0489 12.2599
KP-N-RT-BM-1 GDSC2 3.7183 10.2474 0.1837 17.8482
SJNB-5 GDSC1; GDSC2 3.7835 6.0069 2.342 4.967
CHP-126 GDSC1; GDSC2 4.2247 10.7971 0.3074 15.788
NB(TU)1 GDSC1 4.3336 6.3515 1.6354 1.0819
LA-N-6 GDSC1; GDSC2 5.0837 9.1955 1.6914 6.1286
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 3.566 5.7421 1.5036 3.1007
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MRK-nu-1 GDSC1; GDSC2 -0.2234 6.4594 -1.6971 40.2655
BT-549 GDSC1; GDSC2 0.4961 11.3622 -3.2419 39.9846
OCUB-M GDSC1; GDSC2 2.0233 6.3913 0.6053 21.0661
MDA-MB-453 GDSC1; GDSC2 2.4204 5.7121 1.312 15.5257
MDA-MB-468 GDSC1; GDSC2 2.5523 4.9532 1.801 12.0843
HCC2218 GDSC1; GDSC2 2.5953 4.4336 2.0855 10.1977
CAL-148 GDSC1; GDSC2 2.8049 6.5869 1.2408 14.6401
MCF-7 GDSC1; GDSC2 2.8727 8.8763 0.162 20.4611
Evsa-T GDSC1; GDSC2 2.9646 5.1069 2.1166 8.7071
UACC-893 GDSC1; GDSC2 3.0365 6.4016 1.5382 12.0827
UACC-812 GDSC1 3.0812 4.7793 0.7476 0.944
Hs 578T GDSC1; GDSC2 3.187 12.5379 -1.399 26.1821
BT-474 GDSC1; GDSC2 3.1934 5.5588 2.0946 8.1228
HCC202 GDSC1 3.2098 8.7764 -0.1986 15.9512
COLO 824 GDSC1; GDSC2 3.248 7.1918 1.3251 12.7435
HCC1569 GDSC1; GDSC2 3.3403 8.4907 0.7529 15.8317
HCC2157 GDSC1 3.3517 4.8122 1.7941 1.4226
DU4475 GDSC1; GDSC2 3.3558 7.5594 1.2314 12.9914
MDA-MB-175-VII GDSC1; GDSC2 3.4147 5.1059 2.5061 4.8849
BT-20 GDSC1; GDSC2 3.4552 6.0533 2.0657 7.5463
CAL-51 GDSC1; GDSC2 3.4887 7.3933 1.4235 11.4456
CAMA-1 GDSC1; GDSC2 3.4912 6.7004 1.7716 9.2882
ZR-75-30 GDSC1; GDSC2 3.5232 6.7219 1.7866 9.106
HCC1954 GDSC1; GDSC2 3.6386 6.6326 1.9226 7.9462
MDA-MB-415 GDSC1; GDSC2 3.6412 7.0837 1.7 9.3232
CAL-120 GDSC1; GDSC2 3.6546 12.4566 -0.9712 23.2106
JIMT-1 GDSC1; GDSC2 3.6768 7.2494 1.6456 9.5644
HCC70 GDSC1; GDSC2 3.6846 7.0009 1.7752 8.7415
MFM-223 GDSC1; GDSC2 3.6902 9.1245 0.7215 14.9995
HCC1419 GDSC1; GDSC2 3.718 6.2211 2.1877 6.086
YMB-1-E GDSC2 3.7204 6.6533 1.9756 7.4281
HCC1187 GDSC1; GDSC2 3.721 11.1781 -0.2788 20.0388
EFM-19 GDSC1; GDSC2 3.8542 8.2373 1.2925 11.2412
EFM-192A GDSC1; GDSC2 3.9032 7.7839 1.5549 9.53
BT-483 GDSC1; GDSC2 3.9496 6.6412 2.1518 5.7487
MDA-MB-157 GDSC1; GDSC2 3.95 7.7754 1.5945 9.1703
HCC1500 GDSC1; GDSC2 3.9658 13.2609 -1.1217 22.9398
HDQ-P1 GDSC1; GDSC2 3.9718 7.8266 1.5856 9.1697
HCC1937 GDSC1; GDSC2 3.9733 7.0572 1.9654 6.8392
MDA-MB-361 GDSC1; GDSC2 3.9903 7.2121 1.9019 7.1889
HCC1599 GDSC1; GDSC2 4.0572 7.6225 1.7494 7.9621
HCC1395 GDSC1; GDSC2 4.2998 13.1369 -0.7963 20.7429
MDA-MB-330 GDSC1; GDSC2 4.355 9.2401 1.1734 10.6854
AU565 GDSC1; GDSC2 4.5786 8.2165 1.8261 6.3394
CAL-85-1 GDSC1; GDSC2 4.7116 8.7632 1.6541 7.0741
HCC1428 GDSC1; GDSC2 4.8963 8.4261 1.9321 5.1074
T-47D GDSC1; GDSC2 4.9205 11.1403 0.6516 12.2757
HCC1143 GDSC1; GDSC2 5.1694 8.1254 2.229 3.0352
HCC38 GDSC1; GDSC2 5.1768 12.3827 0.2288 13.881
MDA-MB-436 GDSC1; GDSC2 5.257 8.7071 2.0198 4.01
MDA-MB-231 GDSC1; GDSC2 5.7428 14.1084 -0.2113 14.7477
HCC1806 GDSC1; GDSC2 7.5809 18.2685 -0.97 14.4138
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC1 -7.0936 19.6692 -15.0596 59.847
KS-1 [Human Krukenberg tumour] GDSC1 -4.5905 6.1257 -6.5182 61.369
D-263MG GDSC1 -2.1694 8.8438 -5.1609 49.9597
D-245MG GDSC2 -1.4167 7.2719 -3.2837 48.6346
D-566MG GDSC1; GDSC2 -0.8189 6.0969 -2.1711 44.4507
CAS-1 GDSC1 -0.383 11.077 -4.4733 41.959
D-336MG GDSC1; GDSC2 0.009 12.0903 -4.057 42.8632
SW1088 GDSC1 0.2438 21.6508 -9.1246 45.1517
MOG-G-UVW GDSC1 0.3343 17.8884 -7.174 43.8617
YH-13 GDSC1 0.4357 17.0157 -6.6505 43.1978
SF539 GDSC1 0.9087 6.1218 -0.8543 26.2203
H4 GDSC1 1.2413 4.6984 0.1457 21.2836
MOG-G-CCM GDSC1 1.3097 13.226 -3.9951 37.1044
D-392MG GDSC1 1.6936 13.3178 -3.708 33.3541
8-MG-BA GDSC1 1.7067 5.1644 0.3603 15.7845
T98G GDSC1 1.7862 6.753 -0.3545 22.1105
D-423MG GDSC1; GDSC2 1.7984 9.4817 -1.1044 29.787
U-118MG GDSC1 1.8111 13.7583 -3.8273 35.0904
SF268 GDSC1 2.0207 8.1784 -0.8609 21.9351
D-247MG GDSC1; GDSC2 2.2513 9.2664 -0.5837 26.0393
SW1783 GDSC1 2.2973 9.9454 -1.5104 26.1212
GB-1 GDSC1 2.3428 3.6762 1.6621 4.5585
LN-229 GDSC1 2.3568 7.0077 0.008 17.5352
Onda 10 GDSC1; GDSC2 2.3589 16.696 -4.1837 35.6433
Daoy GDSC1 2.4172 3.9566 1.5826 5.4949
PFSK-1 GDSC1 2.4417 6.1296 0.517 13.6414
LN-18 GDSC1 2.4445 5.4522 0.8577 11.066
YKG-1 GDSC1; GDSC2 2.4854 11.7757 -1.6208 29.1792
DBTRG-05MG GDSC1 2.5192 4.3848 1.4499 6.1944
Becker GDSC1 2.5733 7.5827 -0.102 15.7663
U-251MG GDSC1 2.6889 12.84 -2.6345 29.0365
A-172 GDSC1 2.7222 6.3488 0.6315 11.824
SF295 GDSC1; GDSC2 2.7798 12.8709 -1.9115 29.1738
U-87MG ATCC GDSC1 2.7867 4.6655 1.5112 4.3501
DK-MG GDSC1 2.9089 11.3974 -1.7364 24.9774
LNZTA3WT4 GDSC1 2.9406 11.4845 -1.7546 24.9499
D283 Med GDSC1 2.9637 5.5673 1.198 6.0341
AM-38 GDSC1 3.2311 6.49 0.9383 7.1138
M059J GDSC1 3.2497 12.9202 -2.2253 25.8417
42-MG-BA GDSC1 3.2713 9.3778 -0.4495 17.2899
ONS-76 GDSC1 3.283 7.7416 0.3654 10.7492
SK-MG-1 GDSC1 3.3393 9.0905 -0.2565 15.9071
GaMG GDSC1 3.3429 14.3079 -2.8429 27.7078
SF126 GDSC1; GDSC2 3.3648 10.5126 -0.2377 20.8834
LN-405 GDSC1 3.7522 9.7915 -0.2984 14.9315
NMC-G1 GDSC1; GDSC2 3.8419 6.7561 2.0166 6.842
KNS-42 GDSC1; GDSC2 3.9521 10.6287 0.1795 17.1693
Hs 683 GDSC1; GDSC2 3.9673 6.1738 2.3914 4.2585
D-542MG GDSC1; GDSC2 4.117 11.8651 -0.3065 19.0771
D-502MG GDSC1; GDSC2 4.2182 12.3936 -0.4903 19.6397
SNB-75 GDSC1; GDSC2 4.5334 16.2344 -2.1546 25.0779
KNS-81-FD GDSC1; GDSC2 4.57 12.1117 -0.0812 16.8439
KINGS-1 GDSC1 4.6078 11.0305 -0.3064 11.5591
KALS-1 GDSC1 4.8114 11.7242 -0.5015 12.1723
Onda 11 GDSC1; GDSC2 6.3468 14.3676 0.0708 12.2102
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 2.3201 4.3748 1.294 7.2117
TGBC1TKB GDSC1 2.668 4.2357 1.6359 3.8032
TGBC24TKB GDSC1 4.2279 6.375 1.5775 1.6238
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC1 0.3959 10.6465 -3.5373 39.6627
MFE-280 GDSC1 0.7633 13.8054 -4.7654 40.2129
EN GDSC1 2.0914 9.0421 -1.2322 25.6219
MFE-296 GDSC1 2.5396 9.4459 -1.0603 23.1207
RL95-2 GDSC1 2.5613 5.7555 0.8003 9.8932
KLE GDSC1 2.9905 5.5271 1.2366 6.4128
MFE-319 GDSC1 3.5184 8.2735 0.2747 11.9105
ESS-1 GDSC1 4.3693 13.1006 -1.4711 19.4516
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC1; GDSC2 -1.8098 12.7211 -6.1256 50.5388
769-P GDSC1 0.097 44.6748 -20.736 47.8211
UO-31 GDSC1; GDSC2 0.8628 6.6682 -0.6733 31.9857
RCC10RGB GDSC1 1.0593 3.8325 -0.1584 12.6274
BFTC-909 GDSC1 1.3288 12.3088 -3.5215 36.0706
RXF 393L GDSC1; GDSC2 1.3698 9.6139 -1.5693 32.8696
LB996-RCC GDSC1 1.6502 6.3378 -0.27 19.9815
KTCTL-195 GDSC1 1.7356 3.6402 1.1274 11.7816
VMRC-RCZ GDSC1 1.7868 6.5817 -0.2689 21.5799
786-O GDSC1 2.0294 3.973 1.2415 9.6409
SW13 GDSC1 2.2837 9.257 -1.1775 24.6337
TK-10 GDSC1 2.401 4.4676 1.3142 6.8132
KTCTL-1M GDSC1; GDSC2 2.4404 8.1528 0.1375 22.0995
A-498 GDSC1 2.5084 4.8898 1.1899 7.3529
A-704 GDSC1 2.5618 6.9256 0.2168 15.365
ACHN GDSC1 2.708 6.6382 0.4765 13.0106
KMRC-1 GDSC1 2.7754 8.7036 -0.4993 19.2228
OS-RC-2 GDSC1 2.7927 5.2872 1.211 6.3944
LB2241-RCC GDSC1; GDSC2 2.8541 12.5417 -1.6834 28.1586
SN12C GDSC1 2.8849 5.2671 1.288 6.3222
NCC021 GDSC1; GDSC2 3.001 5.4524 1.9787 9.4838
KTCTL-26A GDSC1; GDSC2 3.0858 5.9236 1.8194 10.2156
CAL-54 GDSC1 3.2051 7.4534 0.4499 11.6143
NCC010 GDSC1; GDSC2 3.2152 5.2388 2.2732 6.9569
SW156 GDSC1; GDSC2 3.2767 10.5866 -0.3482 21.7175
BB65-RCC GDSC1; GDSC2 3.3777 6.3904 1.8339 9.2193
Caki-1 GDSC1; GDSC2 3.4101 14.5822 -2.2349 28.3105
KTCTL-13 GDSC1; GDSC2 3.4659 5.5444 2.3283 5.8846
KMRC-20 GDSC1 3.788 10.828 -0.7797 17.6025
VMRC-RCW GDSC2 3.8786 6.8481 1.9985 6.8877
KTCTL-21 GDSC1; GDSC2 3.9402 6.9127 2.0121 6.6537
HA7-RCC GDSC1; GDSC2 4.3553 8.1843 1.6889 7.636
LB1047-RCC GDSC1; GDSC2 4.4509 9.9466 0.8969 12.0329
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-CO-1 GDSC1 -0.3264 4.6864 -1.4361 38.2666
SW48 GDSC1 -0.3216 2.2025 -0.5313 34.2792
SNU-407 GDSC1 0.0174 4.9641 -1.2017 35.2875
HT115 GDSC1; GDSC2 0.5225 2.7035 0.4107 28.6621
LS180 GDSC1 1.3375 11.1972 -2.9605 34.7036
DiFi GDSC1 1.8525 4.638 0.7527 14.1461
LoVo GDSC1 1.9866 5.5654 0.4129 16.1328
NCI-H508 GDSC1; GDSC2 2.0144 4.6151 1.4126 16.5127
HCT 116 GDSC1 2.2093 5.2147 0.7807 12.516
T84 GDSC1 2.4143 4.3874 1.3651 7.217
NCI-H716 GDSC1 2.4679 6.992 0.1074 14.7935
C2BBe1 GDSC1 2.4704 3.8473 1.6792 4.0502
SNU-C1 GDSC1 2.495 4.1765 1.5346 4.9869
SW626 GDSC1 2.5875 5.5973 0.9 10.2478
SW1463 GDSC1 2.6293 4.7666 1.3454 6.6557
RCM-1 [Human ESC] GDSC1 2.6898 5.7537 0.9022 9.8904
MDST8 GDSC1 2.8468 5.6077 1.0933 7.0569
CaR-1 GDSC1 2.8514 7.7437 0.0387 15.5812
SW1116 GDSC1 2.8594 4.7982 1.498 4.7896
NCI-H747 GDSC1 2.8596 5.0048 1.3979 4.9378
CW-2 GDSC1 2.9053 6.0705 0.9088 8.1588
SNU-C2B GDSC1 2.9808 6.7738 0.6184 11.087
HCT 15 GDSC1 2.9988 4.9689 1.5111 4.3181
COLO205 GDSC1 3.103 7.6229 0.2909 13.0445
LS1034 GDSC1 3.1577 4.672 1.7487 1.9939
HT-55 GDSC1 3.1737 5.0988 1.5629 3.5132
SNU-C5 GDSC1 3.3125 5.8449 1.3017 5.0807
HT-29 GDSC1; GDSC2 3.4688 5.1725 2.516 4.6911
LS123 GDSC1 3.499 7.4421 0.664 8.2669
LS513 GDSC1 3.5123 5.1208 1.7458 1.4605
SW1417 GDSC1 3.5134 5.719 1.4836 3.3401
LS411N GDSC1 3.5364 13.0852 -2.0841 22.796
GP5d GDSC1 3.6506 5.5269 1.6444 2.0433
SNU-81 GDSC1; GDSC2 3.6746 7.7241 1.4074 11.0659
SNU-1040 GDSC1 3.7678 8.7284 0.2289 11.5203
SW620 GDSC1; GDSC2 3.8738 7.9139 1.4681 10.1674
CCK-81 GDSC1 4.0589 6.5636 1.4139 2.806
RKO GDSC1 4.0769 8.3407 0.6192 7.2445
CL-11 GDSC1 4.1128 6.884 1.3038 3.0313
SW837 GDSC1 4.1467 6.1949 1.6122 1.5389
SNU-61 GDSC1 4.248 6.0098 1.7306 0.8687
KM12 GDSC1 4.3672 6.1191 1.7392 0.6565
COLO 320HSR GDSC1 4.393 9.6914 0.1872 9.1938
SNU-283 GDSC2 4.5189 6.3038 2.6707 1.6819
SW948 GDSC1 4.5545 6.1315 1.8086 0.3912
COLO 678 GDSC1 4.6939 6.7313 1.644 0.8646
HCC2998 GDSC1 4.909 7.1242 1.5851 0.829
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 2.7544 4.6084 1.516 4.4005
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-HEP-1 GDSC1 -0.276 3.1101 -0.7618 35.1782
SNU-423 GDSC1 0.8286 10.4066 -3.0236 36.8494
JHH-7 GDSC1 1.2281 3.909 0.5002 18.838
SNU-398 GDSC1 1.498 7.5475 -1.0057 26.9381
JHH-6 GDSC1 1.5748 4.5682 0.5283 17.023
Hep 3B2.1-7 GDSC1; GDSC2 1.8217 6.1833 0.507 22.4464
JHH-2 GDSC1 2.2998 11.1855 -2.1283 28.5951
Huh-7 GDSC1 2.6027 5.9642 0.7292 11.496
Hep-G2/C3A GDSC1 2.6185 14.0205 -3.2821 31.1927
JHH-4 GDSC1 2.6443 4.2369 1.618 4.4872
HLE GDSC1 2.773 7.2355 0.2302 14.5412
SNU-449 GDSC1 2.8891 4.8246 1.5059 4.648
JHH-1 GDSC1 3.0009 7.3671 0.3405 13.0211
HuH-1 GDSC1 3.2444 11.7698 -1.657 23.5589
SNU-387 GDSC1 3.5242 5.7421 1.4795 3.3466
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 185 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UMC-11 GDSC1 -2.5208 2.7066 -3.0729 57.1879
NCI-H810 GDSC1 -1.5436 3.1617 -2.1526 48.7692
HCC44 GDSC1 -0.9825 2.6876 -1.3904 42.7906
NCI-H1975 GDSC1 -0.9312 11.0001 -4.9565 44.5872
NCI-H2171 GDSC1; GDSC2 -0.2385 3.6542 -0.6593 37.3714
LK-2 GDSC1 -0.1677 1.4433 -0.2153 31.418
HOP-92 GDSC1 0.0648 8.9914 -3.0402 40.1839
NCI-H1963 GDSC1 0.0768 2.1058 -0.3094 18.2207
NCI-H847 GDSC1 0.5042 4.874 -0.6668 27.0577
NCI-H524 GDSC1 0.5994 2.9869 0.2262 21.375
NCI-H292 GDSC1; GDSC2 0.7217 18.3803 -6.4706 42.8654
NCI-H2722 GDSC1 0.7662 17.5215 -6.6103 42.2274
EMC-BAC-2 GDSC1 0.7722 23.053 -9.3618 44.0641
IST-SL1 GDSC1; GDSC2 0.8975 5.1781 0.011 28.7819
NCI-H1436 GDSC1; GDSC2 0.9335 7.4423 -0.957 32.6342
VMRC-LCD GDSC1 1.0285 5.9423 -0.6537 27.2538
NCI-H1755 GDSC1 1.0291 17.2082 -6.2243 41.1212
NCI-H661 GDSC1 1.0529 8.7652 -2.0101 33.041
A-549 GDSC1 1.0535 6.624 -0.96 28.7231
NCI-H2369 GDSC1 1.0946 3.168 0.6843 18.1739
NCI-H460 GDSC1; GDSC2 1.3316 5.0659 0.5116 24.4234
Lu-135 GDSC1 1.4381 5.8668 -0.2319 22.8607
NCI-H2170 GDSC1 1.5532 9.7944 -2.0728 31.1812
A-427 GDSC1; GDSC2 1.6183 4.4566 1.0649 20.1465
NCI-H211 GDSC1 1.6223 8.126 -1.182 24.9793
NCI-H1155 GDSC1 1.6427 5.2232 0.2725 16.6045
LXF 289 GDSC1 1.8965 7.7235 -0.7411 21.7435
RERF-LC-Sq1 GDSC1 1.9142 7.2686 -0.4989 22.4464
NCI-H1703 GDSC1 2.0469 4.8101 0.8419 12.6747
SBC-5 GDSC1 2.0712 7.6036 -0.5307 22.0048
Lu-139 GDSC1 2.0746 3.8292 1.3534 7.6297
NCI-H1355 GDSC1 2.0788 6.135 0.2092 15.4347
SK-LU-1 GDSC1 2.1181 9.5505 -1.4636 26.5796
SBC-1 GDSC1; GDSC2 2.1337 7.6403 0.1071 23.2765
CPC-N GDSC1 2.2492 3.9888 1.4271 6.5111
NCI-H69 GDSC1 2.2705 9.1118 -1.116 22.3662
NCI-H647 GDSC2 2.2758 10.1088 -0.9784 27.6125
NCI-H2081 GDSC1; GDSC2 2.3188 6.6922 0.742 19.2217
EPLC-272H GDSC1 2.3553 6.9683 0.0265 17.4169
NCI-H2373 GDSC1 2.382 12.0193 -2.4768 29.5293
NCI-H1581 GDSC1 2.4028 4.7062 1.1965 7.6312
NCI-H226 GDSC1 2.4403 7.1931 -0.0157 15.6586
NCI-H2023 GDSC1 2.4474 3.9201 1.6249 5.0595
NCI-H720 GDSC1 2.4508 8.9234 -0.872 20.5356
Calu-3 GDSC1 2.4723 5.0075 1.1023 9.0758
BEN GDSC1; GDSC2 2.5395 11.5233 -1.4477 28.4256
NCI-H2342 GDSC1 2.5459 4.6955 1.3162 7.1541
COR-L279 GDSC1 2.5633 6.0898 0.6352 12.336
HARA [Human squamous cell lung carcinoma] GDSC1 2.5643 8.097 -0.3662 19.1687
NCI-H1341 GDSC1 2.597 7.9648 -0.2736 18.4804
LCLC-103H GDSC1 2.5975 6.7105 0.3528 14.2806
HCC33 GDSC1; GDSC2 2.6598 9.0307 -0.1014 22.4615
HCC827 GDSC1 2.6698 4.4855 1.5146 5.2129
NCI-H1694 GDSC1 2.674 6.2669 0.6346 10.6833
NCI-H1869 GDSC1 2.6769 5.6333 0.952 8.5061
NCI-H358 GDSC1 2.6775 5.1309 1.2016 7.6207
Lu-99A GDSC1 2.7092 5.7862 0.901 9.8363
NCI-H596 GDSC1 2.7157 5.452 1.0718 8.5038
RERF-LC-KJ GDSC1 2.7336 4.5386 1.5351 4.8637
HOP-62 GDSC1 2.7562 8.2378 -0.2824 16.2818
SBC-3 GDSC1 2.7917 6.3523 0.6836 11.2084
Calu-6 GDSC1 2.7943 5.1991 1.2555 6.0837
NCI-H841 GDSC1 2.796 5.7242 0.9979 8.8171
NCI-H2009 GDSC1 2.7996 10.4798 -1.3661 23.6987
NCI-H2461 GDSC1 2.8122 5.9215 0.9126 9.4168
NCI-H2591 GDSC1 2.8125 5.7044 1.0201 8.5959
NCI-H1838 GDSC1 2.826 4.7414 1.5022 4.3127
NCI-H522 GDSC1 2.8553 6.054 0.8796 9.5318
Lu-165 GDSC1 2.8684 5.5998 1.1131 6.8629
DMS 273 GDSC1 2.8723 5.1595 1.3316 6.0251
LOU-NH91 GDSC1 2.9161 36.0185 -14.0338 42.4781
COR-L105 GDSC1 2.972 9.207 -0.595 19.1118
NCI-H2595 GDSC1 2.979 6.3186 0.8413 9.4386
NCI-H1944 GDSC1 2.9926 8.166 -0.0617 15.7743
COR-L95 GDSC1 3.0014 5.8421 1.091 6.6645
SHP-77 GDSC1 3.0086 6.4617 0.7927 8.6659
NCI-H2405 GDSC1 3.0346 22.2487 -7.054 37.0536
NCI-H838 GDSC1; GDSC2 3.0406 9.318 0.0863 20.3678
COLO 668 GDSC1 3.0777 5.1348 1.4845 3.8367
Ms-1 GDSC1 3.094 5.2677 1.4321 4.1461
NCI-H2731 GDSC1 3.1291 6.5198 0.8517 8.9145
NCI-H128 GDSC1 3.1301 10.7493 -1.983 17.7116
NCI-H2085 GDSC1 3.1492 6.3408 0.9533 8.0993
LC-2/ad GDSC1; GDSC2 3.151 5.2692 2.2024 7.5741
NCI-H1993 GDSC1 3.1537 5.5754 1.3253 5.3047
NCI-H727 GDSC1 3.2091 5.5067 1.3943 4.6554
PaCa-3 GDSC1 3.2118 7.677 0.345 12.3316
NCI-H1693 GDSC1 3.2286 7.1836 0.599 10.4761
COR-L321 GDSC1; GDSC2 3.2346 8.3589 0.7303 16.3283
NCI-H1573 GDSC1 3.2418 5.6274 1.3586 4.8369
NCI-H1437 GDSC1; GDSC2 3.2424 4.9756 2.4279 5.8959
NCI-H2172 GDSC1; GDSC2 3.254 9.6717 0.0903 19.6859
NCI-H1793 GDSC1 3.2564 11.1776 -1.3533 22.1427
NCI-H290 GDSC1; GDSC2 3.2819 8.0484 0.9253 15.0677
NCI-H2110 GDSC1; GDSC2 3.3069 6.3243 1.8082 9.6181
EBC-1 GDSC1 3.327 20.9188 -6.1527 35.1413
NCI-H146 GDSC1; GDSC2 3.3961 7.4734 1.3076 12.4564
Lu-134-A GDSC1; GDSC2 3.4385 7.3867 1.3859 11.8172
IA-LM GDSC1 3.4508 13.337 -2.2754 25.4229
SW1573 GDSC1 3.4629 10.6403 -0.9289 19.3767
NCI-H2347 GDSC1 3.4638 6.924 0.8889 7.7148
NCI-H748 GDSC1; GDSC2 3.4707 7.0702 1.5703 10.5947
NCI-H1781 GDSC1 3.4714 5.1246 1.7229 1.8472
SW1271 GDSC1 3.4809 14.53 -2.8452 27.3157
NCI-H2818 GDSC1 3.4822 8.7109 0.0353 13.6151
EMC-BAC-1 GDSC1; GDSC2 3.4906 7.3247 1.4593 11.259
NCI-H441 GDSC1 3.4957 6.2338 1.2362 5.1183
NCI-H1568 GDSC1 3.5077 6.2662 1.2287 5.1442
DMS 114 GDSC1 3.5131 5.2005 1.7123 1.6407
NCI-H1048 GDSC1 3.5179 6.189 1.271 4.8188
HCC78 GDSC1 3.5298 5.6051 1.5442 2.8988
NCI-H526 GDSC1 3.5317 8.5809 0.1344 11.553
SK-MES-1 GDSC1 3.5331 7.2799 0.7652 8.426
NCI-H2135 GDSC1; GDSC2 3.5377 6.6679 1.8251 8.8261
NCI-H2029 GDSC1; GDSC2 3.5438 5.6561 2.3342 5.6377
COR-L303 GDSC2 3.5525 8.1442 1.1001 13.2523
HCC15 GDSC1 3.563 8.3724 0.2582 11.895
NCI-H209 GDSC1 3.5635 11.5653 -1.3102 19.3746
NCI-H1651 GDSC1 3.5674 6.2555 1.2708 4.7086
NCI-H446 GDSC1 3.569 17.4754 -4.2422 29.4475
NCI-H1876 GDSC1 3.5799 9.1187 -0.0936 12.8138
NCI-H520 GDSC1 3.5834 5.578 1.5861 2.524
NCI-H1915 GDSC1 3.5862 6.7941 1.0313 6.3756
NCI-H1770 GDSC1; GDSC2 3.594 9.4084 0.5024 16.4768
NCI-H2030 GDSC1; GDSC2 3.6228 8.7161 0.8713 14.3877
NCI-H2444 GDSC1; GDSC2 3.6381 5.7181 2.3761 5.1298
ABC-1 GDSC1; GDSC2 3.6406 7.7704 1.3573 11.4635
NCI-H1299 GDSC1 3.6693 6.3696 1.2802 3.9332
NCI-H2228 GDSC1 3.6904 10.4953 -0.6879 17.3824
NCI-H2196 GDSC1; GDSC2 3.691 6.7328 1.9134 7.8656
Lu-65 GDSC1 3.7127 9.2836 -0.079 12.3832
NCI-H1792 GDSC1 3.7358 13.5169 -2.1454 24.0929
NCI-H82 GDSC1 3.7393 9.9389 -0.3797 14.0636
NCI-H2066 GDSC1 3.7996 5.597 1.6904 1.5548
NCI-H1304 GDSC1 3.8078 10.4446 -0.5775 14.9866
NCI-H510A GDSC1; GDSC2 3.8345 11.1377 -0.1674 19.1976
NCI-H2803 GDSC1; GDSC2 3.842 7.1017 1.846 7.9248
NCI-H1688 GDSC1 3.846 9.9949 -0.3305 14.858
PC-14 GDSC1; GDSC2 3.8874 6.8025 2.0274 6.6868
NCI-H1105 GDSC1; GDSC2 3.8901 9.6309 0.6275 15.0168
NCI-H740 GDSC2 3.8908 7.1247 1.8713 7.646
NCI-H2795 GDSC1 3.8924 6.1166 1.5183 2.4314
NCI-H2291 GDSC1; GDSC2 3.9004 5.9604 2.4482 4.0594
NCI-H2804 GDSC1; GDSC2 3.9078 6.7324 2.0769 6.3305
EKVX GDSC1; GDSC2 3.9271 9.1132 0.9139 13.2654
KNS-62 GDSC1 3.9327 5.689 1.7163 1.2501
NCI-H3255 GDSC1; GDSC2 3.9474 8.8237 1.0733 12.3316
COR-L88 GDSC1 3.9571 12.8612 -1.6548 19.8856
NCI-H23 GDSC1 3.9592 6.3277 1.4628 2.3707
NCI-H250 GDSC2 3.9675 9.5936 0.7065 14.3707
NCI-H1650 GDSC1 3.9689 7.01 1.1666 4.0778
NCI-H1623 GDSC1 3.9834 6.0434 1.5956 1.8395
NCI-H2227 GDSC1; GDSC2 4.0047 11.1834 -0.0553 18.1916
NCI-H345 GDSC1; GDSC2 4.0214 5.6372 2.6824 2.4019
NCI-H835 GDSC1 4.0274 8.9893 0.28 10.4924
COR-L23 GDSC1 4.0712 10.508 -0.4209 14.7676
NCI-H2141 GDSC1 4.0812 5.7788 1.7477 0.8383
CAL-12T GDSC1; GDSC2 4.0908 8.6268 1.2798 10.7449
LCLC-97TM1 GDSC1 4.0942 6.2299 1.5727 1.8183
NCI-H650 GDSC1 4.2223 13.3837 -1.7162 20.9525
HCC366 GDSC1; GDSC2 4.2371 10.5986 0.4153 15.2377
NCI-H1648 GDSC1 4.2597 6.3881 1.5871 1.3656
DMS 79 GDSC1; GDSC2 4.2911 8.77 1.3573 9.7608
NCI-H1092 GDSC1 4.3705 11.8354 -0.8546 15.042
NCI-H1563 GDSC1 4.3968 6.4922 1.6082 1.2816
DMS 53 GDSC1 4.3993 6.5415 1.5899 1.3672
NCI-H64 GDSC1 4.4036 11.4682 -1.4707 11.7857
NCI-H2122 GDSC1 4.4066 5.994 1.8013 0.4905
NCI-H196 GDSC1 4.4801 12.8998 -1.2942 18.3204
ChaGo-K-1 GDSC1; GDSC2 4.5348 9.4938 1.1791 10.2616
LC-1/sq GDSC1 4.5729 7.5631 1.2543 2.9683
NCI-H322M GDSC1 4.6631 9.2816 0.5455 6.5246
COR-L32 GDSC1; GDSC2 4.7187 9.2796 1.4115 8.5003
NCI-H1435 GDSC1 4.7311 6.4684 1.7553 0.4586
NCI-H1836 GDSC1; GDSC2 4.7799 8.988 1.5924 7.2925
LB647-SCLC GDSC1; GDSC2 4.7949 12.182 0.0514 15.6492
NCI-H1734 GDSC2 4.8715 7.8221 2.1945 3.6918
RERF-LC-MS GDSC1; GDSC2 4.9544 14.3386 -0.8922 19.5485
NCI-H513 GDSC1 5.049 7.1074 1.6474 0.6204
NCI-H1666 GDSC1 5.0538 7.0723 1.662 0.5088
NCI-H2869 GDSC1; GDSC2 5.154 8.7939 1.92 4.7389
NCI-H2087 GDSC1 5.2147 7.2085 1.6744 0.4584
NCI-H2810 GDSC1; GDSC2 5.4196 13.0661 0.068 14.1699
IST-SL2 GDSC1; GDSC2 5.4993 15.0014 -0.8176 17.9313
NCI-H187 GDSC1 8.6356 19.8333 -1.9 11.6684
⏷ Show the Full List of 185 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 2.4924 5.0332 1.1056 7.9893
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-70 GDSC1 -1.2683 2.2163 -1.5678 45.6453
KYSE-410 GDSC1 -0.1661 15.4519 -6.4166 44.8362
T.T GDSC1 2.099 5.485 0.551 14.6719
KYSE-180 GDSC1 2.4639 9.0947 -0.9469 22.8124
OE19 GDSC1 2.5236 4.1132 1.5883 5.0955
KYSE-450 GDSC1 2.5803 3.9259 1.7238 3.8605
EC-GI-10 GDSC1 2.6033 4.3207 1.5462 4.5968
TE-8 GDSC1 2.6315 7.7548 -0.1411 15.8219
TE-4 GDSC1 2.6922 6.9703 0.2986 14.3372
TE-1 GDSC1 2.7441 4.661 1.4829 4.6543
TE-11 GDSC1; GDSC2 2.8264 7.3749 0.869 16.821
KYSE-270 GDSC1 2.9106 8.9501 -0.5152 18.8551
TE-6 GDSC1 3.0747 5.124 1.4876 3.8229
TE-5 GDSC1 3.1946 5.0468 1.5998 2.8466
TE-9 GDSC1 3.1995 6.7012 0.8136 8.0254
OE33 GDSC1 3.3263 5.6624 1.3961 4.3623
TE-15 GDSC1 4.1539 7.2767 1.1534 3.8355
KYSE-510 GDSC1; GDSC2 4.4319 7.1299 2.2444 4.1881
TE-10 GDSC1; GDSC2 4.7839 11.3628 0.4452 13.6836
COLO 680N GDSC1 4.7913 7.0334 1.5702 1.0862
OE21 GDSC1 4.8909 18.9412 -3.956 26.9444
KYSE-140 GDSC1 5.0073 7.7884 1.371 1.7872
KYSE-520 GDSC1 5.1154 7.0195 1.7042 0.4229
KYSE-150 GDSC1 5.2048 16.6374 -2.5988 21.9556
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC1 1.3677 6.5714 -0.6424 25.6064
OC 314 GDSC1 1.3769 3.4185 0.8712 15.3921
OVTOKO GDSC1 1.4602 17.1656 -5.8297 39.4578
RMG-I GDSC1 1.9156 4.8623 0.699 14.2928
TOV-21G GDSC1 1.9757 5.2532 0.5586 15.1035
JHOS-4 GDSC2 2.3195 5.7069 1.2175 16.5106
Caov-3 GDSC2 2.3645 7.8382 0.2235 21.9276
DOV13 GDSC1 2.4044 5.4587 0.8217 11.4843
TYK-nu GDSC1 2.4264 8.6742 -0.7676 21.9919
OVCAR-8 GDSC1 2.6254 6.9978 0.2318 15.037
FU-OV-1 GDSC1 2.6519 5.7806 0.8593 10.3428
IGROV-1 GDSC1 2.6714 5.2769 1.1246 8.2376
OAW42 GDSC1 2.6917 5.2616 1.1477 7.9933
OVCAR-4 GDSC1 2.7909 7.0146 0.3541 12.2033
Caov-4 GDSC1 2.8722 5.1236 1.349 5.8916
OV56 GDSC1 2.9527 5.0482 1.4419 4.96
TOV-112D GDSC1 2.9783 11.2881 -1.6265 24.2782
OVK18 GDSC1; GDSC2 3.0262 11.8752 -1.2036 26.0183
OVCAR-3 GDSC1 3.1155 7.857 0.1847 13.7365
EFO-21 GDSC1 3.3683 6.8146 0.8765 8.0596
OV-90 GDSC1 3.601 17.4319 -4.1954 30.7272
OVISE GDSC1 3.6578 7.4062 0.7884 7.9368
JHOS-2 GDSC1; GDSC2 3.8201 7.6007 1.5822 9.6098
OVCAR-5 GDSC1 3.9076 13.6363 -2.0742 23.3226
OVKATE GDSC1 4.0196 5.5883 1.7947 0.7914
ES-2 GDSC1 4.0431 10.7752 -0.5704 14.3471
SK-OV-3 GDSC1 4.3257 16.3819 -3.116 25.8855
Kuramochi GDSC1 4.4824 9.3854 0.3873 7.8149
OAW28 GDSC1 4.8151 7.6739 1.3277 2.2278
EFO-27 GDSC1; GDSC2 5.5084 13.2406 0.0454 14.0844
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-4 GDSC1 0.3741 5.8238 -1.2334 33.4039
HuP-T4 GDSC1 0.8147 5.1194 -0.4701 27.2896
HPAF-II GDSC1 1.9763 6.0989 0.1382 18.1224
CFPAC-1 GDSC1 2.3169 3.749 1.6042 5.6786
SUIT-2 GDSC1 2.5588 4.1131 1.6153 4.7718
PSN1 GDSC1 2.6419 5.2959 1.0925 7.6363
Panc 10.05 GDSC1 2.665 6.6359 0.4438 13.3937
PaTu 8988t GDSC1 2.6754 8.4477 -0.4516 19.2891
KP-3 GDSC1 2.7621 7.8236 -0.0712 16.6101
BxPC-3 GDSC1 2.768 5.1725 1.2491 6.97
PaTu 8902 GDSC1 2.796 4.441 1.6267 3.9855
DAN-G GDSC1 2.8215 5.2693 1.241 6.8703
HPAC GDSC1 3.0312 6.5561 0.7629 9.8648
YAPC GDSC1 3.2558 4.8863 1.709 2.3192
HuP-T3 GDSC1 3.2991 5.6367 1.3909 4.4635
KP-1N GDSC1 3.428 8.9679 -0.1303 14.8445
Panc 02.03 GDSC1 3.7683 7.8341 0.658 8.5764
AsPC-1 GDSC1 3.878 10.3237 -0.468 15.5822
KP-2 GDSC1 3.8935 8.2478 0.5441 9.0495
SW1990 GDSC1 4.0502 6.3854 1.4855 2.3841
SU.86.86 GDSC1 4.0659 5.4457 1.8674 0.4736
Panc 08.13 GDSC1 4.073 6.2017 1.574 1.8393
Hs 766T GDSC1 4.1781 6.2548 1.6027 1.551
PL4 GDSC1 4.1891 6.939 1.321 3.1684
MZ-PC-1 GDSC1; GDSC2 4.2887 6.6587 2.374 3.6911
Capan-1 GDSC1 4.4348 6.2363 1.723 0.7507
Panc 03.27 GDSC1 4.5209 6.1988 1.7715 0.5215
QGP-1 GDSC1; GDSC2 4.9494 11.8344 0.334 13.9104
Panc 04.03 GDSC1 5.138 6.8405 1.7747 0.2523
Capan-2 GDSC1 5.5489 7.4802 1.7015 0.2761
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1 0.5208 3.7916 -0.1756 24.199
MPP 89 GDSC1 0.612 8.0186 -2.0523 32.575
NCI-H2452 GDSC1 2.3211 9.7558 -1.3957 25.5208
IST-Mes1 GDSC1 2.5192 3.8547 1.7131 3.6735
NCI-H28 GDSC1 4.1216 11.7682 -0.9983 17.8145
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC1 1.5504 3.2169 1.1377 12.5693
LNCaP clone FGC GDSC1 3.1672 5.4443 1.3965 4.2168
PC-3 GDSC1 3.7159 11.9519 -1.3865 20.8959
NCI-H660 GDSC2 3.9681 5.5719 2.6791 2.5304
VCaP GDSC1 4.1898 5.7056 1.8211 0.4949
22Rv1 GDSC1 4.3362 13.0811 -1.4854 19.6069
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 4.8298 6.648 1.7286 0.4335
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-7951 GDSC1 0.1225 13.6044 -5.2429 42.9583
COLO 792 GDSC1 0.5226 5.6495 -1.0056 31.6023
CHL-1 GDSC1 0.932 7.7023 -1.5993 32.0931
Hs 940.T GDSC1; GDSC2 0.9701 12.1274 -3.1671 38.2053
A101D GDSC1 1.4391 10.4063 -2.4777 30.7853
SH-4 GDSC1 1.9068 7.6175 -0.6793 21.3724
A2058 GDSC1 2.1071 5.4994 0.5508 14.6423
LOX-IMVI GDSC1 2.1136 5.4136 0.5992 12.7171
IGR-37 GDSC1 2.1902 4.1473 1.2973 8.5694
G-361 GDSC1 2.323 7.1634 -0.098 18.3616
COLO 829 GDSC1 2.3293 12.3075 -2.6647 28.4295
IST-MEL1 GDSC1 2.4247 7.7233 -0.2936 17.3995
HMV-II GDSC1 2.4716 5.4093 0.9012 10.6368
G-mel GDSC1; GDSC2 2.4839 7.4073 0.5448 19.8022
HT-144 GDSC1 2.5039 7.6204 -0.1772 16.4464
SK-MEL-2 GDSC1 2.6582 5.0089 1.2474 6.5157
GAK GDSC1 2.6845 3.956 1.7838 2.7531
UACC-62 GDSC1 2.8992 5.9834 0.9472 8.8833
SK-MEL-1 GDSC1 3.0042 5.7967 1.1151 6.4935
WM278 GDSC1 3.1049 8.3177 -0.051 15.3409
WM793 GDSC1 3.1411 10.0191 -0.8671 20.0649
UACC-257 GDSC1 3.1414 8.6638 -0.1946 14.6179
M14 GDSC1 3.2161 5.1541 1.5635 3.4125
Mel JuSo GDSC1 3.2982 10.213 -0.8425 19.4298
IGR-1 GDSC1 3.3675 5.2029 1.6313 2.6263
SK-MEL-24 GDSC1 3.3748 9.5193 -0.4414 16.9183
COLO 679 GDSC1 3.3847 11.4333 -1.3812 21.8724
SK-MEL-30 GDSC1; GDSC2 3.4405 6.6698 1.7458 9.6245
MZ-MEL-2 GDSC1; GDSC2 3.4572 6.1564 2.0158 7.8536
SK-MEL-3 GDSC1; GDSC2 3.5416 5.1026 2.6073 3.9247
LB373-MEL-D GDSC1; GDSC2 3.5567 5.0397 2.65 3.6061
LB2518-MEL GDSC1; GDSC2 3.6868 6.8337 1.8601 8.2086
A-375 GDSC1; GDSC2 3.6979 12.1106 -0.7631 22.2949
MeWo GDSC1 3.7171 7.452 0.8056 7.665
IPC-298 GDSC1; GDSC2 3.7411 6.1679 2.2314 5.7765
A-431 GDSC1; GDSC2 3.7537 5.8301 2.4069 4.6522
Mel Ho GDSC1; GDSC2 3.8291 6.0493 2.3544 4.7993
SK-MEL-28 GDSC1; GDSC2 3.8508 5.8604 2.4618 4.0869
WM1552C GDSC1 3.8827 5.917 1.5982 1.9668
VMRC-MELG GDSC1; GDSC2 3.9364 6.235 2.3403 4.6391
SK-MEL-5 GDSC1; GDSC2 3.9468 6.9384 2.0043 6.6861
MMAc-SF GDSC1; GDSC2 4.0854 6.5657 2.2838 4.6397
451Lu GDSC1; GDSC2 4.1195 6.174 2.4932 3.3307
COLO 783 GDSC1; GDSC2 4.1413 5.7376 2.7093 2.0447
A-388 GDSC1; GDSC2 4.1794 6.5267 2.3655 3.955
RVH-421 GDSC1; GDSC2 4.2672 6.653 2.3628 3.8109
SK-MEL-31 GDSC1; GDSC2 4.2712 11.452 0.0184 17.1715
WT2-iPS GDSC1; GDSC2 4.3321 8.2664 1.6326 8.0527
MZ-MEL-7 GDSC1; GDSC2 4.3323 5.9658 2.7168 1.6998
Hs 938.T GDSC1; GDSC2 4.3399 8.2145 1.6633 7.8504
CP66-MEL GDSC1; GDSC2 4.4225 7.7451 1.9467 5.9485
WM115 GDSC1 4.5165 12.2608 -0.9587 16.5464
CP50-MEL-B GDSC1; GDSC2 4.6148 9.3442 1.3084 9.3292
WM35 GDSC1 4.6409 6.563 1.6852 0.7458
DJM-1 GDSC1; GDSC2 4.6634 7.3502 2.2856 3.5215
COLO 800 GDSC1; GDSC2 5.2667 10.7963 1.0548 9.3362
EquiPSC Line K2 GDSC1; GDSC2 3.9599 8.0677 1.4575 10.0102
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 1.6269 5.152 0.78 21.6465
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC1 -3.6646 4.0359 -4.7484 62.5627
GCT GDSC1 -2.3318 9.8221 -5.7712 52.8292
MES-SA GDSC1 -1.3773 2.9611 -1.9062 47.1192
SW982 GDSC1 -1.1949 10.0978 -4.7802 47.7631
HT-1080 GDSC1 -0.7057 2.3083 -0.9785 39.1842
MFH-ino GDSC1 0.4232 10.7263 -3.5514 37.3654
SW872 GDSC1 0.4859 7.1532 -1.754 32.0507
A-204 GDSC1 1.204 11.6912 -3.3241 36.085
RKN GDSC1 1.8188 6.4024 -0.1514 20.7005
VA-ES-BJ GDSC1 2.4263 3.6807 1.7275 3.8432
G-401 GDSC1 2.6081 6.8268 0.3033 14.5952
SK-LMS-1 GDSC1 2.7161 20.6883 -6.5349 35.7991
EW-8 GDSC1 2.7774 4.734 1.4712 4.648
Rh30 GDSC1 2.8121 11.0344 -1.6329 24.8555
G-402 GDSC1 2.8533 12.6197 -2.3911 27.6843
Rh41 GDSC1 3.1407 9.3159 -0.5184 18.1135
KYM-1 GDSC1 3.1454 15.8835 -3.7854 29.3733
RD GDSC1 3.5392 6.1118 1.3198 4.4253
TE 441.T GDSC1; GDSC2 3.5827 7.3765 1.5076 10.6685
STS-0421 GDSC1; GDSC2 3.6529 11.5432 -0.5162 21.363
Rh18 GDSC1 3.7808 11.9561 -1.34 20.4846
SK-UT-1 GDSC1 3.9171 11.015 -0.7775 15.774
SW684 GDSC1 6.1029 22.9203 -5.0214 25.8404
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Fu97 GDSC1 -0.5566 3.121 -1.0691 38.4701
HGC-27 GDSC1 0.8517 6.5819 -1.1301 30.5005
AGS GDSC1 1.456 5.7365 -0.1516 22.2707
GCIY GDSC1 1.7144 3.4288 0.575 4.6126
RERF-GC-1B GDSC1 1.9266 8.5462 -1.1255 25.7525
SNU-1 GDSC1 1.934 15.313 -4.4996 34.3634
HSC-39 GDSC1 2.1469 5.767 0.4515 13.6009
MKN1 GDSC1 2.538 6.3479 0.4861 13.5264
SNU-16 GDSC1 2.6035 4.6204 1.3981 5.6241
23132/87 GDSC1 2.6942 5.9742 0.796 10.6835
IM95 GDSC1 2.7409 5.5714 1.0318 8.7312
Hs 746.T GDSC1 2.8792 5.597 1.1225 7.6074
NUGC-3 GDSC1 2.9189 5.4226 1.2365 6.6177
ECC10 GDSC1 2.9315 5.5401 1.1882 6.9501
MKN45 GDSC1 3.0351 5.1514 1.4484 4.693
NUGC-4 GDSC1 3.0607 5.4204 1.3367 5.463
RF-48 GDSC1 3.1231 8.3437 -0.0501 13.7982
SK-GT-2 GDSC1 3.2747 10.1449 -0.8267 19.419
TGBC11TKB GDSC1 3.285 6.3689 1.0339 7.1251
MKN28 GDSC1 3.6475 5.9525 1.4561 3.2624
SCH GDSC1; GDSC2 3.662 6.3841 2.0642 7.0007
KATO III GDSC1 3.9478 6.7326 1.2789 3.8688
TMK-1 GDSC1; GDSC2 4.023 9.0478 1.0202 12.4425
MKN7 GDSC1; GDSC2 4.0978 6.8914 2.1351 5.5333
ECC12 GDSC1; GDSC2 4.1457 7.0581 2.0878 5.695
NCI-N87 GDSC1 4.3394 6.8618 1.4312 2.2812
SNU-5 GDSC1 4.5496 6.2856 1.751 0.5086
SNG-M GDSC1 0.8698 3.524 0.3012 22.0535
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-62 GDSC1 -0.2021 11.6822 -4.5983 43.5079
ASH-3 GDSC1 1.0114 8.4379 -1.8868 32.7966
BHT-101 GDSC1 1.3252 4.2403 0.4436 18.7834
K5 GDSC1 1.8891 5.491 0.3637 15.0905
FTC-133 GDSC1 2.0557 17.1319 -5.3061 37.061
B-CPAP GDSC1 2.4012 10.5838 -1.7431 26.7384
WRO GDSC1 2.4097 9.5548 -1.2216 24.3835
KMH-2 GDSC1; GDSC2 2.7417 10.5035 -0.7632 25.1981
TT2609-C02 GDSC1 2.938 5.3396 1.2906 6.1499
TT GDSC1 3.2523 8.7665 -0.1617 15.5846
CGTH-W-1 GDSC1 3.3566 5.082 1.679 2.0701
HTC-C3 GDSC1 3.4348 5.6939 1.4483 3.7483
8305C GDSC1 3.7844 10.8642 -0.8001 17.724
8505C GDSC1 4.0113 6.1091 1.5821 1.8775
ML-1 [Human leukemia] GDSC1; GDSC2 4.2401 10.4456 0.4934 14.8158
IHH-4 GDSC1 4.4427 5.93 1.8381 0.3611
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB49-HNC GDSC1 -7.0485 11.8074 -11.4553 63.534
HSC-3 GDSC1 -2.5199 13.4365 -7.6502 52.8241
HO-1-N-1 GDSC1 1.2544 12.1974 -3.5314 36.359
Detroit 562 GDSC1 1.2964 8.0213 -1.4218 29.7322
PCI-38 GDSC1 1.7472 8.2451 -1.1313 26.5035
CAL-33 GDSC1 2.0346 11.5886 -2.553 30.9806
CAL-27 GDSC1 2.3856 12.8938 -2.911 30.8806
HSC-4 GDSC1 2.4853 12.5769 -2.6701 29.814
DOK GDSC1 2.5651 14.7839 -3.7076 32.4525
SCC-9 GDSC1 2.6683 4.6499 1.4325 5.8549
BICR 22 GDSC1 2.7367 5.0812 1.2708 6.8983
BICR 78 GDSC1 2.7653 6.8502 0.4158 13.2556
Ca9-22 GDSC1 2.8623 6.5804 0.6245 11.4175
SKN-3 GDSC1 2.9634 5.3591 1.299 6.0142
SCC-4 GDSC1 2.9965 6.4103 0.809 9.6273
PCI-04B GDSC1; GDSC2 3.1169 7.142 1.2385 13.7109
LB771-HNC GDSC1 3.1289 7.8706 0.188 12.3008
HO-1-u-1 GDSC1 3.1812 12.2664 -1.9536 24.9989
SAS GDSC1 3.2088 5.8174 1.2466 5.7471
OSC-19 GDSC1; GDSC2 3.2276 7.6608 1.0734 14.3614
NCI-H3118 GDSC1 3.2713 6.3597 1.029 7.1979
UPCI-SCC-090 GDSC1 3.2821 8.24 0.12 13.6559
OSC-20 GDSC1 3.2881 5.7399 1.3355 4.8933
HSC-2 GDSC1 3.3463 4.816 1.7896 1.6364
KON GDSC1; GDSC2 3.469 8.7611 0.7239 15.6667
PCI-15A GDSC1; GDSC2 3.511 9.4181 0.4299 17.1575
JHU-022 GDSC1 3.6334 10.4035 -0.6848 17.534
PCI-30 GDSC1 3.7034 10.9794 -0.9164 18.585
JHU-011 GDSC1; GDSC2 3.8079 8.3932 1.1791 12.0793
KOSC-2 GDSC1; GDSC2 3.9537 8.1097 1.432 10.1804
PCI-06A GDSC1; GDSC2 3.9592 6.4272 2.263 5.0623
BHY GDSC1; GDSC2 4.0392 6.3888 2.3373 4.431
JHU-029 GDSC1; GDSC2 4.2469 9.6172 0.908 12.513
BB30-HNC GDSC1; GDSC2 4.2964 12.6567 -0.5603 19.7429
BICR 10 GDSC1 4.3286 14.1498 -2.0144 21.9229
BICR 31 GDSC2 4.3956 10.8782 0.397 14.9284
FaDu GDSC1 4.5346 11.3648 -0.5149 14.0871
SCC-15 GDSC1 4.5586 17.8128 -3.6476 26.8879
PE/CA-PJ15 GDSC1; GDSC2 5.4196 10.9393 1.0874 8.8788
SCC-25 GDSC1; GDSC2 5.6873 14.3205 -0.3525 15.5479
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1710 GDSC1 0.2219 5.0601 -1.0362 33.3954
5637 GDSC1 1.5698 8.3613 -1.3454 28.2303
CAL-29 GDSC1 2.0157 10.0535 -1.8019 28.3826
J82 GDSC1 2.2309 21.4803 -7.3332 39.2046
KU-19-19 GDSC1 2.3556 6.7723 0.1247 16.7493
UM-UC-3 GDSC1 2.3934 6.3576 0.3633 14.9344
RT-112 GDSC1 2.4394 4.7147 1.222 8.2539
639V GDSC1 2.5377 7.2195 0.0506 16.5894
647V GDSC1 2.572 6.5666 0.4042 14.0012
TCCSUP GDSC1 2.7283 5.9576 0.8307 10.309
HT-1197 GDSC1 3.061 7.6322 0.2548 13.4276
SW780 GDSC1 3.0723 7.412 0.3719 12.5739
HT-1376 GDSC1 3.1832 7.8054 0.2607 13.0045
BFTC-905 GDSC1 4.0219 5.6751 1.7621 0.9342
RT-4 GDSC1 4.4341 7.2682 1.3082 2.8586
T24 GDSC1; GDSC2 5.0215 10.6814 0.9442 10.4944
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
C-33 A GDSC1 -1.3223 10.6918 -5.1858 48.4429
TC-YIK GDSC1 -0.4284 5.9278 -2.0849 40.7379
ACC-OV7 GDSC1; GDSC2 -0.0796 16.5261 -6.2923 44.9684
Ca Ski GDSC1 0.3683 7.527 -2.0459 36.3276
KGN GDSC1 0.6391 10.3205 -3.1539 35.6545
PWR-1E GDSC1 1.466 11.2717 -2.8849 34.0216
HeLa GDSC1 1.6624 8.6594 -1.4119 28.1412
PEO1 GDSC1 1.8961 4.6431 0.7899 13.6823
NT2-D1 GDSC1 1.9383 4.5202 0.8887 11.3459
JAR GDSC1; GDSC2 1.9505 8.6022 -0.5331 26.9089
HEC-1 GDSC1 2.0495 5.1797 0.6601 14.0487
MS751 GDSC1 2.0647 5.3191 0.6039 14.4118
SKN GDSC1 2.1903 12.9235 -3.0889 32.0329
C-4-I GDSC1 2.3492 6.8532 0.079 17.0852
HEY GDSC1 2.3999 7.2786 -0.0917 18.0345
SiHa GDSC1 2.5518 4.6299 1.3535 6.8425
CAL-39 GDSC1 2.6081 6.4872 0.4727 13.3797
SiSo GDSC1 2.629 4.8849 1.2865 7.1153
ME-180 GDSC1 2.7322 7.2283 0.2017 14.8775
SW756 GDSC1 2.805 8.1945 -0.2222 17.4317
OVMIU GDSC1 2.9025 6.1427 0.8712 9.4484
SKG-IIIa GDSC1 2.9111 5.8518 1.0207 8.2888
BPH-1 GDSC1 2.9676 6.8714 0.5603 11.5526
OVCA420 GDSC1 3.2188 12.2379 -1.9099 24.7043
LB831-BLC GDSC1 3.417 18.7917 -5.0191 31.5537
SW954 GDSC1; GDSC2 3.4248 7.6004 1.2678 12.5718
DSH1 GDSC1 3.4458 13.3085 -2.2651 23.7444
NCC-IT GDSC1 3.4616 5.1133 0.7794 0.5302
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 3.7375 5.6992 2.4593 4.3503
NEC8 GDSC1 3.7918 5.8517 1.5791 1.9727
JHOS-3 GDSC1; GDSC2 3.8895 6.8981 1.982 6.9635
HT-3 GDSC1 3.8919 6.4141 1.3887 3.2522
OVCA433 GDSC1; GDSC2 4.1274 16.3001 -2.5087 27.2047
DoTc2 4510 GDSC1 4.1337 6.0418 1.6677 1.2703
UWB1.289 GDSC1; GDSC2 4.1422 7.0527 2.088 5.7216
JEG-3 GDSC1; GDSC2 4.2318 10.462 0.4789 14.9144
OV17R GDSC1; GDSC2 4.4965 7.3915 2.1629 4.5409
SW962 GDSC1; GDSC2 4.6055 13.8426 -0.9108 20.4332
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug

References

1 Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities. J Pharmacol Exp Ther. 2007 Jan;320(1):89-98.