Details of the Drug

General Information of Drug (ID: DM5KXFI)

Drug Name
NUTLIN-3
Synonyms
Nutlin-3; 548472-68-0; 890090-75-2; nutlin-3A; nutlin 3; (+/-)-Nutlin3; CHEMBL211045; Nutlin 3(Random Configuration); MDM2 Antagonist, Nutlin-3, Racemic; 4-(4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one; 4-({4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one; 4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 581.5
Logarithm of the Partition Coefficient (xlogp) 5.2
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C30H30Cl2N4O4
IUPAC Name
4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one
Canonical SMILES
CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
InChI
InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)
InChIKey
BDUHCSBCVGXTJM-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
216345
ChEBI ID
CHEBI:93777
CAS Number
548472-68-0
UNII
53IA0V845C
DrugBank ID
DB17039
TTD ID
D01QKK
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cellular tumor antigen p53 (TP53) TT7SBF5 P53_HUMAN Inhibitor [1]
Mdm2 messenger RNA (MDM2 mRNA) TT9TE0O MDM2_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cellular tumor antigen p53 (TP53) DTT TP53 7.01E-01 0.06 0.09
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 5.3997 7.3476 2.6659 0.7896
SJSA-1 GDSC1; GDSC2; CTRP2; CCLE 1.4489 3.609 1.4434 36.4315
CADO-ES1 GDSC1; GDSC2 2.2772 4.3746 1.788 12.8344
CHSA8926 GDSC1; GDSC2 3.1376 7.0546 1.2999 12.8711
ES4 GDSC1; GDSC2 3.1508 7.064 1.3065 12.7928
EW-7 GDSC1; GDSC2 3.4658 7.0748 1.564 10.3557
CHSA0011 GDSC1; GDSC2 3.4988 6.8273 1.7144 9.6569
CAL-72 GDSC1; GDSC2 4.2545 6.0057 2.6545 2.0939
EW-3 GDSC1; GDSC2 4.2901 7.8518 1.8043 6.8938
TC-71 GDSC1; GDSC2; CCLE 4.2953 5.6269 2.8439 0.9263
HuO9 GDSC1; GDSC2 4.3948 6.4642 2.5293 2.5425
ES1 GDSC1; GDSC2 4.6645 6.5151 2.6567 1.5139
EW-1 GDSC1; GDSC2 4.7564 6.8323 2.5688 1.8194
ES6 GDSC1; GDSC2 4.778 6.8011 2.5936 1.6743
H-EMC-SS GDSC1; GDSC2 4.8283 10.9616 0.6731 12.0691
ES8 GDSC1; GDSC2 4.8567 8.3013 1.9654 4.8528
EW-12 GDSC2 4.8654 6.8724 2.6081 1.5527
EW-13 GDSC1; GDSC2 4.8664 7.4955 2.0511 2.2899
NY GDSC1; GDSC2 4.9461 7.9208 2.1935 3.464
U2OS GDSC1; GDSC2; CTRP2; CCLE 5.0584 9.3038 4.0904 17.0913
NOS-1 [Human HNSCC] GDSC1; GDSC2 5.089 8.0901 2.1997 3.2157
Hs 888.T CTRP2 5.1072 15.6697 1.1319 27.8973
SK-PN-DW GDSC1; GDSC2 5.1646 8.0799 2.2463 2.8702
SW1353 CTRP2; CCLE 5.3112 10.6334 3.7486 17.7358
U-CH2 GDSC2 5.3942 7.2839 2.688 0.7425
EW-24 GDSC1; GDSC2 5.4158 6.7829 2.88 0.2055
EW-22 GDSC1; GDSC2 5.4818 7.2 2.7556 0.4656
ES7 GDSC1; GDSC2 5.4864 7.8013 2.5262 1.235
MHH-ES-1 GDSC1; GDSC2; CTRP2; CCLE 5.5881 7.4623 5.3694 11.0698
A-673 GDSC1; GDSC2; CTRP2; CCLE 5.6423 7.1091 5.5286 10.3687
Hs 822.T CTRP2 5.6453 10.3367 4.2165 16.0493
EW-11 GDSC1; GDSC2 5.7751 8.6594 2.3145 1.8305
CHSA0108 GDSC1; GDSC2 6.0445 8.2514 2.5929 0.6489
SK-N-MC CTRP2 6.088 8.0828 5.6789 9.1063
ES5 GDSC1; GDSC2 6.1218 8.7948 2.4193 1.1643
EW-18 GDSC1; GDSC2 6.1268 8.1474 2.663 0.4135
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 6.2284 7.3082 6.1144 7.0601
SaOS-2 GDSC1; GDSC2; CTRP2; CCLE 6.2816 8.9837 5.4757 8.9148
SK-ES-1 GDSC1; GDSC2; CTRP2; CCLE 6.4904 7.3503 6.3868 4.9999
TC71 CTRP2 6.5424 7.1791 6.4926 4.7415
MG-63 GDSC1; GDSC2; CTRP2; CCLE 6.5594 7.1438 6.5196 4.3477
CAL-78 GDSC1; GDSC2; CTRP2; CCLE 6.5776 8.3173 6.0783 5.9194
HOS GDSC1; GDSC2; CTRP2; CCLE 6.7369 7.1586 6.7094 3.189
EW-16 GDSC1; GDSC2 6.8086 14.5871 0.262 10.225
HuO-3N1 GDSC1; GDSC2 6.8975 8.9788 2.6546 0.2089
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 223 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 2.1676 5.6864 2.0373 34.1073
MEC1 CTRP2 5.633 7.5723 5.3827 11.5133
JM1 GDSC1; GDSC2; CTRP2 2.8493 5.1591 2.8171 29.2565
MV4-11 GDSC1; GDSC2; CTRP2 -0.4759 1.3516 -0.4761 51.2804
BC-1 GDSC1; GDSC2 -0.1078 2.2548 -0.193 33.7451
CRO-AP2 GDSC1; GDSC2 0.0734 3.3435 -0.2292 34.0314
HC-1 GDSC1; GDSC2 0.1265 2.5827 0.0051 31.6502
IM-9 GDSC1; GDSC2 0.1779 1.8738 0.1521 30.6889
SUP-B15 GDSC1; GDSC2; CTRP2 0.2178 1.3119 0.2178 46.663
MOLM-13 GDSC1; GDSC2; CTRP2 0.2345 2.8656 0.2275 46.5657
BONNA-12 GDSC2 0.25 2.715 0.1135 31.5088
MOLT-16 GDSC1; GDSC2; CTRP2; CCLE 0.2644 1.984 0.2642 43.8773
LC4-1 GDSC1; GDSC2 0.3264 2.3128 0.2629 29.4311
NKM-1 GDSC1; GDSC2 0.3722 2.8779 0.2123 29.4611
MOLT-4 GDSC1; GDSC2 0.3889 2.5057 0.3013 28.9429
EoL-1 GDSC1; GDSC2; CTRP2 0.5206 2.2821 0.5202 44.6492
KMS-21-BM CTRP2 0.6273 3.4425 0.6126 43.9752
Hs 445 GDSC2 0.6632 3.2131 0.4494 26.9168
BV-173 GDSC1; GDSC2; CTRP2 0.7004 2.9202 0.6973 43.4601
SU-DHL-5 GDSC1; GDSC2; CTRP1 0.805 2.2606 0.8049 45.1835
MOLT-3 CTRP2 0.8228 2.7995 0.8214 42.6409
697 GDSC1; GDSC2; CTRP2; CCLE 0.8293 2.3769 0.8291 40.3186
SUP-M2 GDSC1; GDSC2; CTRP2; CCLE 0.8723 2.5352 0.872 40.0478
OCI-Ly19 GDSC1; GDSC2; CTRP2 0.9106 3.831 0.8879 42.1157
NALM-6 GDSC1; GDSC2; CTRP2 0.969 2.9805 0.967 41.67
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 0.9767 2.9088 0.9752 41.6171
JVM-3 GDSC1; GDSC2; CTRP2; CCLE 0.9866 3.7782 0.9681 39.3812
Hs 611.T CTRP2 1.0607 4.5845 0.9936 41.2365
RS4;11 GDSC1; GDSC2; CTRP2 1.0963 2.8477 1.0956 40.8186
DoHH2 GDSC1; GDSC2; CTRP2; CCLE 1.1311 3.2114 1.1281 38.4257
RPMI-8866 GDSC1; GDSC2 1.1753 3.5256 0.9206 22.888
QIMR-WIL GDSC1; GDSC2 1.251 3.3508 1.0539 21.8195
RCH-ACV GDSC1; GDSC2; CTRP2 1.2676 3.1878 1.2656 39.6827
Ki-JK CTRP2 1.2908 4.3308 1.2535 39.6338
JVM-2 GDSC1; GDSC2 1.3233 4.2125 0.8461 21.9338
ML-2 GDSC1; GDSC2 1.346 3.5177 1.109 20.4266
MY-M12 GDSC1; GDSC2 1.3843 3.003 1.2851 19.959
Karpas-1106P GDSC1; GDSC2 1.3861 3.7393 1.0822 20.3959
CTB-1 GDSC1; GDSC2 1.4013 4.5655 0.7917 22.5992
HAL-01 GDSC1; GDSC2 1.4754 2.7474 1.4296 18.1771
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 1.5336 3.9986 1.5197 37.9504
JSC-1 GDSC1; GDSC2 1.604 4.8988 0.8659 20.6768
VAL GDSC1; GDSC2 1.6258 3.5022 1.4187 17.555
NCI-H929 GDSC1; GDSC2; CTRP2 1.6323 2.9943 1.6322 37.2491
SUP-HD1 GDSC1; GDSC2; CTRP2 1.7051 4.2266 1.6866 36.8241
KE-97 CTRP2; CTRP1; CCLE 1.7333 4.4377 1.7053 34.7095
L-540 GDSC1; GDSC2; CTRP2 1.788 4.2483 1.7708 36.2687
RPMI-6666 GDSC1; GDSC2; CTRP2 1.849 4.1998 1.8351 35.8522
MHH-CALL-4 GDSC2; CTRP2 1.8547 4.1803 1.8416 35.8118
OCI-AML-5 GDSC1; GDSC2; CTRP2; CCLE 1.9235 3.8478 1.9194 33.437
A3/Kawakami GDSC1; GDSC2; CTRP2 1.9654 3.7199 1.9632 35.0391
CESS GDSC1; GDSC2 1.9824 4.8318 1.2852 16.8478
CTV-1 GDSC1; GDSC2 2.1352 3.9918 1.7977 13.3393
Kasumi-2 CTRP2; CCLE 2.1529 4.8704 2.1128 32.1051
BC-3 GDSC2 2.166 4.5258 1.6078 14.7577
AMO1 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 2.1701 3.5543 2.1697 31.8717
MM1.S GDSC1; GDSC2; CTRP2 2.2917 4.25 2.2848 32.883
EHEB GDSC1; CTRP2 2.3067 5.2208 2.2434 32.9692
Granta-519 GDSC1; GDSC2; CTRP2; CCLE 2.3098 4.5689 2.2927 31.0446
NU-DHL-1 CTRP2 2.3575 5.9054 2.2067 32.9159
OCI-AML-2 GDSC1; GDSC2; CTRP2; CCLE 2.3728 3.5595 2.3727 30.5939
KOPN-8 GDSC1; GDSC2 2.4064 5.5238 1.3886 14.6968
RC-K8 GDSC1; GDSC2 2.4305 4.6571 1.8182 12.0832
P30/OHK GDSC1; GDSC2 2.4496 3.7497 2.2266 9.6652
YT GDSC1; GDSC2 2.471 4.9068 1.743 12.3789
CML-T1 GDSC1; GDSC2; CTRP2 2.5181 4.6781 2.502 31.4069
Farage GDSC1; GDSC2 2.5536 5.5058 1.5383 13.7307
Reh GDSC1; GDSC2; CTRP2; CCLE 2.5704 4.6757 2.5557 29.3953
SIG-M5 GDSC2; CTRP2; CCLE 2.5816 3.7233 2.5815 29.2782
OCI-Ly3 CTRP2 2.6452 4.3231 2.6414 30.5199
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 2.8118 5.3271 2.7637 29.4683
VL51 GDSC1; GDSC2 2.8877 5.2147 1.9931 9.4609
MN-60 GDSC1; GDSC2 2.9182 5.8101 1.7272 10.9733
HuNS1 CTRP2 2.9186 4.0288 2.9184 28.6879
SEM CTRP2 2.9217 5.6042 2.8521 28.9007
MOLP-8 GDSC1; GDSC2; CTRP2; CCLE 2.9785 5.5081 2.9224 26.9561
OCI-Ly7 GDSC1; GDSC2 3.0099 4.815 2.3017 7.4276
Daudi GDSC1; GDSC2; CTRP2 3.0582 4.5743 3.0549 27.7696
KM-H2 GDSC1; GDSC2; CTRP2 3.1179 5.3715 3.0813 27.4837
MHH-CALL-3 CTRP2 3.1195 8.1043 2.4778 29.5141
SUP-B8 GDSC1; GDSC2 3.1691 6.1481 1.7795 10.2094
JM-1 CCLE 3.463 5.3155 2.2017 3.3004
Pfeiffer CTRP2; CCLE 3.4867 5.3218 3.468 23.6351
MHH-CALL-2 GDSC1; GDSC2 3.5419 5.8264 2.248 5.9926
EB1 CTRP2; CCLE 3.5757 5.6132 3.5403 23.1275
Loucy GDSC1; GDSC2 3.6158 5.5214 2.4565 4.536
OPM-2 GDSC1; GDSC2; CTRP2; CCLE 3.7135 4.4679 3.7135 22.147
MJ CCLE 3.7801 9.4392 0.4051 12.0582
Peer CTRP2 3.8256 5.4705 3.8099 22.7035
BDCM CCLE 3.8487 6.0813 2.0962 3.1441
GA-10 GDSC1; GDSC2; CTRP2 3.8629 5.4883 3.8474 22.4546
WSU-NHL GDSC1; GDSC2 3.9127 5.8283 2.5204 3.4802
SCC-3 GDSC2 3.9146 5.1488 2.8425 1.631
ALL-PO GDSC1; GDSC2 3.9356 7.2439 1.8459 7.4542
P32/ISH GDSC1; GDSC2 3.9433 5.2569 2.8102 1.76
U-698-M GDSC1; GDSC2 4.005 5.955 2.5219 3.2838
EB2 GDSC1; GDSC2; CCLE 4.0139 5.4608 2.7594 1.6501
WIL2 NS GDSC1; GDSC2 4.0479 6.6091 2.237 4.8658
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 4.065 6.3751 3.9661 21.3945
DB GDSC1; GDSC2; CTRP2 4.0737 6.2775 3.9909 21.2807
KY821 GDSC1; GDSC2 4.0802 6.5728 2.2768 4.5625
GR-ST GDSC1; GDSC2 4.0958 8.3272 1.4313 9.53
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 4.0963 7.387 3.7658 22.006
Ku812 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.118 5.6296 4.1032 19.6457
Jiyoye GDSC1; GDSC2 4.1274 6.191 2.4903 3.2284
DG-75 GDSC1; GDSC2 4.144 5.8389 2.6646 2.2199
Karpas-45 GDSC1; GDSC2 4.1522 6.614 2.3058 4.2444
ARH-77 GDSC1; GDSC2 4.1924 5.9789 2.6297 2.3296
MOLT-13 GDSC1; GDSC2; CTRP2 4.2202 7.0477 3.9931 20.8127
ALL-SIL GDSC1; GDSC2; CTRP2; CCLE 4.2234 6.9243 4.0267 19.5787
MEC-1 CCLE 4.2312 7.3838 1.7296 4.3541
KE-37 GDSC1; GDSC2; CTRP2 4.2438 6.2704 4.174 20.1042
Jurkat GDSC1; GDSC2; CTRP2; CCLE 4.2628 5.8508 4.2393 18.7609
SU-DHL-16 GDSC1; GDSC2 4.3153 7.849 1.8233 6.9424
RPMI-8402 GDSC1; GDSC2; CTRP2; CCLE 4.3641 6.5062 4.266 18.365
ATN-1 GDSC1; GDSC2 4.3749 7.1785 2.1848 4.5048
CCRF-CEM GDSC1; GDSC2 4.3876 6.741 2.3978 3.2757
ST486 GDSC1; GDSC2; CTRP2 4.419 6.271 4.3609 18.898
P12-Ichikawa GDSC1; GDSC2; CTRP2; CCLE 4.4774 6.1411 4.4384 17.4586
CMK-86 CCLE 4.4851 7.0142 2.0538 2.4029
NCO2 CTRP2; CCLE 4.486 6.7306 4.3554 17.7046
A4/Fukuda GDSC1; GDSC2; CTRP2 4.4963 6.3951 4.4261 18.4253
NOMO-1 GDSC1; GDSC2; CTRP1 4.4978 5.6813 4.4908 19.1553
REC-1 CTRP2 4.5063 6.7752 4.3681 18.5955
PL-21 GDSC1; GDSC2 4.514 7.9516 1.9093 6.0013
SU-DHL-6 GDSC1; GDSC2; CTRP2; CCLE 4.5151 6.3999 4.4455 17.3207
Mono-Mac-1 CTRP2; CCLE 4.5215 6.6391 4.4118 17.412
MLMA GDSC1; GDSC2 4.5676 7.0341 2.3726 3.1088
SU-DHL-1 GDSC2; CTRP2 4.5808 6.1363 4.5479 17.7353
EM-2 GDSC1; GDSC2; CTRP2; CCLE 4.6022 6.094 4.5745 16.6362
KMS-34 CTRP2; CCLE 4.6096 6.1865 4.5732 16.6177
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 4.6227 6.8442 4.4797 17.8382
JeKo-1 GDSC1; GDSC2; CTRP2 4.6266 6.9712 4.4549 17.9138
Ri-1 CTRP2 4.629 6.7848 4.4993 17.7498
M-07e CTRP2 4.6405 6.9058 4.4853 17.7631
BE-13 GDSC1; GDSC2 4.6672 9.7819 1.1329 9.9254
KMS-12-BM GDSC2; CTRP2; CCLE 4.6689 6.3321 4.6191 16.2875
BALL-1 GDSC1; GDSC2 4.677 6.9936 2.4546 2.5024
KG-1 GDSC1; GDSC2; CCLE 4.6824 6.6823 2.5943 1.5394
P31/FUJ GDSC1; GDSC2; CTRP2; CCLE 4.7 7.1282 4.4958 16.6046
MHH-PREB-1 GDSC1; GDSC2 4.7115 6.9086 2.5114 2.1625
BL-70 CTRP2; CTRP1; CCLE 4.7527 5.7841 4.7479 15.6149
PL21 CTRP2; CTRP1 4.758 6.871 4.6209 16.9175
MEG-01 GDSC1; GDSC2; CCLE 4.7609 6.9014 2.5414 1.6742
KCL-22 GDSC1; GDSC2; CTRP2; CCLE 4.7866 6.5943 4.7061 15.6459
PF-382 GDSC1; GDSC2; CTRP2 4.8192 7.2884 4.5826 16.8664
NK-92MI GDSC2 4.8322 6.3083 2.8217 0.6767
L-1236 GDSC1; GDSC2 4.8496 7.0313 2.5325 1.8771
HuT 78 CTRP2; CCLE 4.8498 7.2752 4.6196 15.751
HH [Human lymphoma] GDSC1; GDSC2; CCLE 4.877 7.1565 2.493 1.7479
BL-41 GDSC1; GDSC2; CCLE 4.9695 6.0011 2.9895 0.1157
H9 GDSC1; GDSC2 4.9871 7.7635 2.2873 2.913
CA46 GDSC1; GDSC2; CTRP2 4.9923 7.081 4.8268 15.4605
JURL-MK1 GDSC1; GDSC2; CTRP2 5.0109 7.1774 4.8221 15.4202
ME1 GDSC1; GDSC2 5.029 6.3907 2.8729 0.3717
SU-DHL-8 GDSC1; GDSC2; CTRP2; CCLE 5.1296 6.6472 5.0665 13.4286
F-36P CTRP2; CCLE 5.1382 7.2447 4.9429 13.8177
MOLM-6 CTRP2 5.1591 8.1835 4.6528 15.6139
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 5.211 7.1148 5.0567 13.9662
Ramos.2G6.4C10 GDSC1; GDSC2 5.2287 8.225 2.2178 2.925
LAMA-84 GDSC1; GDSC2; CTRP2 5.2558 7.7388 4.9175 14.3416
DND-41 GDSC1; GDSC2; CTRP2 5.2878 6.8686 5.1969 13.2311
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 5.2942 6.7933 5.2185 13.1354
TUR GDSC1; GDSC2 5.3063 6.9153 2.7904 0.4586
KMS-26 CTRP2; CCLE 5.3129 7.1059 5.1701 12.54
Sc-1 GDSC1 5.3187 6.9517 2.4686 0.4015
KMS-11 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.3235 7.8061 4.9675 13.2132
KHM-1B CTRP2; CCLE 5.4022 7.1802 5.2484 12.0153
HT CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.4284 6.7097 5.3775 11.5068
KMOE-2 GDSC1; GDSC2 5.4295 7.6458 2.5622 1.144
LP-1 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.4394 7.3187 5.2507 11.9007
SUP-T11 CTRP2 5.4488 7.2738 5.2737 12.4606
ME1 CTRP2 5.4645 7.4172 5.2488 12.5039
TK [Human B-cell lymphoma] GDSC1; GDSC2 5.4817 6.7009 2.9317 0.1089
KO52 CTRP2; CCLE 5.5082 7.1977 5.3595 11.331
AML-193 CTRP2 5.5088 6.2532 5.5046 11.462
Karpas-231 GDSC1; GDSC2 5.513 6.6831 2.9485 0.0839
DEL GDSC1; GDSC2; CTRP2; CCLE 5.5481 6.0288 5.5479 10.5894
HD-MY-Z CTRP2; CCLE 5.6038 7.0887 5.4916 10.606
HEL GDSC1; GDSC2; CTRP2 5.6066 6.9609 5.5237 11.0823
Raji GDSC1; GDSC2; CTRP2; CCLE 5.6118 7.2466 5.4592 10.6929
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 5.6424 7.5056 5.4147 11.367
MOTN-1 CTRP2 5.6844 7.8634 5.3357 11.5411
U-937 CTRP2; CTRP1; CCLE 5.7036 7.2926 5.5465 10.1309
Karpas-299 GDSC1; GDSC2; CTRP2; CCLE 5.7227 7.6355 5.4585 10.384
EJM GDSC1; GDSC2; CTRP2; CTRP1 5.8303 7.1904 5.7129 9.7174
TF-1 CTRP2 5.8346 8.6642 5.1684 11.7798
SU-DHL-4 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.8557 7.5365 5.6362 9.3917
JJN-3 GDSC1; GDSC2; CTRP2 5.8673 7.4036 5.6918 9.6823
L-428 GDSC1; GDSC2; CTRP2; CCLE 5.869 7 5.8004 8.7903
HDLM-2 GDSC1; GDSC2; CTRP2 5.8911 7.6144 5.648 9.775
K-562 GDSC1; GDSC2; CTRP2 5.8953 7.6109 5.6538 9.7411
KMS-20 CTRP2 5.9627 7.1619 5.8648 8.7673
KMS-27 CTRP2 5.9646 6.6222 5.9559 8.4434
Mono-Mac-6 GDSC1; GDSC2 5.9881 8.6109 2.4323 1.1808
KMM-1 CTRP2; CCLE 6.0772 8.2353 5.6038 8.9246
SUP-T1 GDSC1; GDSC2; CTRP2; CCLE 6.1057 7.7822 5.8175 8.0688
Ci-1 CTRP2; CCLE 6.1303 6.8131 6.1126 6.9774
Mino CTRP2; CCLE 6.1492 6.892 6.1226 6.8872
NB4 GDSC1; GDSC2; CTRP2 6.1694 7.3337 6.0423 7.4994
ROS-50 GDSC1; GDSC2 6.1862 12.2161 0.9746 8.0528
L-363 GDSC1; GDSC2; CTRP2; CCLE 6.1921 7.7227 5.9325 7.4251
HEL 92.1.7 CTRP2; CCLE 6.2143 7.1232 6.1486 6.607
RL GDSC1; GDSC2; CTRP2 6.3313 7.1502 6.2696 6.1875
HL-60 GDSC1; GDSC2; CTRP2 6.3847 9.1505 5.4979 9.0785
Kasumi-1 GDSC2; CTRP2 6.3901 8.591 5.7654 7.9799
U266B1 GDSC1; GDSC2; CTRP2 6.4206 7.3564 6.3089 5.7755
SU-DHL-10 GDSC1; GDSC2; CTRP2; CCLE 6.4367 8.1909 5.9938 6.5767
KMS-18 CTRP2 6.4521 7.6871 6.2233 6.008
Namalwa GDSC1; GDSC2; CTRP2 6.4608 7.3216 6.3636 5.4551
OCI-M1 GDSC1; GDSC2; CTRP2 6.4854 7.1031 6.4481 5.0763
HPB-ALL CTRP2 6.4862 9.8632 5.251 9.8568
KYO-1 CTRP2 6.5059 7.2132 6.4441 5.027
OCI-Ly10 CTRP2; CTRP1; CCLE 6.5371 10.6562 4.9093 10.5619
MC116 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.5577 8.4952 5.9759 6.3579
Karpas-422 GDSC1; GDSC2; CTRP2; CCLE 6.6348 7.242 6.5769 3.9344
SR GDSC1; GDSC2; CTRP2 6.6523 7.6494 6.4501 4.5844
SK-MM-2 GDSC1; GDSC2; CTRP2; CCLE 6.6656 7.7056 6.4406 4.3406
CMK GDSC1; CTRP2 6.6802 7.1701 6.645 3.7733
P3HR-1 CTRP2; CTRP1; CCLE 6.8597 8.5151 6.257 4.5939
Karpas-620 GDSC1; GDSC2; CTRP2; CCLE 6.9071 7.671 6.7041 2.7584
MOLP-2 CTRP2 6.916 7.6292 6.732 2.7802
Toledo CTRP2; CCLE 7.1047 16.879 2.3 19.0182
⏷ Show the Full List of 223 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 5.8716 6.9653 5.8104 9.243
TE15 CTRP2 6.2857 7.6147 6.0733 7.0456
T.T GDSC1; GDSC2 4.6596 6.5769 2.6276 1.6583
KYSE-270 GDSC1; GDSC2 5.1123 7.9678 2.2668 2.8398
TE-15 GDSC1; GDSC2; CCLE 5.213 7.4391 2.5442 1.2175
TE-6 GDSC1; GDSC2; CTRP2 5.257 6.9826 5.1388 13.5318
KYSE-140 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.3 7.1115 5.1547 13.3426
TE-4 GDSC1; GDSC2; CTRP2 5.7682 7.4138 5.5807 10.3844
TE-9 GDSC1; GDSC2; CTRP2; CCLE 5.7794 6.5892 5.7652 9.1767
TE-14 CTRP2 5.7981 7.0813 5.7051 9.8443
KYSE-180 GDSC1; GDSC2; CTRP2; CCLE 5.8141 7.6194 5.563 10.3153
KYSE-70 GDSC1; GDSC2; CTRP2; CCLE 5.8549 8.1451 5.408 10.2133
TE-5 GDSC1; GDSC2; CTRP2; CCLE 5.8795 7.0241 5.8067 8.738
TE-10 GDSC1; GDSC2; CTRP2 5.9288 7.4185 5.7541 9.2711
KYSE-410 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.9561 7.889 5.6168 9.1893
TE-8 GDSC1; GDSC2 5.9862 7.8905 2.7014 0.3807
TE-11 GDSC1; GDSC2; CTRP2; CCLE 6.0187 8.3175 5.5082 9.4263
EC-GI-10 GDSC1; GDSC2; CTRP2 6.0418 7.6911 5.7832 8.8347
OE21 GDSC1; GDSC2; CTRP2; CCLE 6.1193 8.5008 5.5324 9.0863
KYSE-520 GDSC1; GDSC2; CTRP2; CCLE 6.1216 7.751 5.8464 7.9224
OE19 GDSC1; GDSC2; CTRP2 6.3608 7.644 6.1428 6.5698
COLO 680N GDSC1; GDSC2; CTRP2 6.3624 7.2508 6.2771 6.0653
KYSE-450 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.381 7.864 6.0767 6.4072
OE33 GDSC1; GDSC2; CTRP2; CCLE 6.4047 7.5094 6.2397 5.7542
KYSE-150 GDSC1; GDSC2; CTRP2; CCLE 6.413 7.0158 6.3863 5.2259
KYSE-510 GDSC1; GDSC2; CTRP2; CCLE 6.471 7.1358 6.4252 4.9243
KYSE-30 CTRP2; CCLE 6.5542 7.0599 6.5309 4.3255
TE-1 GDSC1; GDSC2; CTRP2; CCLE 6.6498 8.2312 6.1898 5.3246
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.3589 7.3092 6.2563 6.1515
Panc 05.04 CTRP2 4.4254 9.2433 3.4547 22.1884
HuP-T4 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.8836 6.5828 4.8124 15.0047
PaTu 8988s CTRP2 5.0107 6.7886 4.9126 15.0996
PL45 CCLE 5.074 7.7148 2.0644 1.6913
Capan-2 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.4457 6.994 5.3415 11.5742
PL4 GDSC1; GDSC2 5.4894 7.0255 2.8218 0.2993
MIA PaCa-2 GDSC1; GDSC2; CTRP2; CCLE 5.5035 6.8503 5.4341 11.0944
SU.86.86 GDSC1; GDSC2; CTRP2; CCLE 5.5285 6.8132 5.468 10.9077
MZ-PC-1 GDSC1; GDSC2 5.6112 7.7974 2.5836 0.9532
KP-3 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.6241 8.5037 5.0181 12.2373
KP-1N GDSC1; GDSC2; CCLE 5.7398 7.8373 2.6231 0.6097
KCI-MOH1 CCLE 5.7773 8.0888 2.2339 0.6228
HPAC CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.8545 7.2937 5.7108 9.1361
PaTu 8988t GDSC1; GDSC2; CTRP2 5.9803 7.4935 5.7858 9.0029
KP-4 GDSC1; GDSC2; CTRP2; CCLE 6.055 6.7501 6.0399 7.4431
PK-45H CTRP2; CCLE 6.0663 8.1216 5.6401 8.8183
QGP-1 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.0712 7.5971 5.8487 8.0502
BxPC-3 GDSC1; GDSC2; CTRP2; CCLE 6.1182 7.7017 5.8613 7.8782
KP-1NL CCLE 6.1811 9.0626 2.0343 0.9541
Panc 10.05 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.2359 8.0117 5.8634 7.5628
PK-1 CCLE 6.2372 8.4742 2.2733 0.3564
HPAF-II GDSC1; GDSC2; CTRP2; CCLE 6.338 8.134 5.9176 7.1051
SNU-213 CTRP2 6.4037 16.3453 1.9659 22.4666
Panc 08.13 GDSC1; GDSC2; CTRP2 6.4332 8.1182 6.0223 6.844
HuP-T3 GDSC1; GDSC2; CTRP2; CCLE 6.4594 8.3814 5.9308 6.7602
CFPAC-1 GDSC1; GDSC2; CTRP2; CTRP1 6.4627 7.4338 6.329 5.5775
Hs 766T GDSC1; GDSC2; CTRP2; CCLE 6.4878 7.1672 6.4361 4.8382
AsPC-1 GDSC1; GDSC2; CTRP2; CCLE 6.4939 8.1449 6.0725 6.141
Capan-1 GDSC1; GDSC2; CTRP2 6.526 7.4189 6.4026 5.1194
KP-2 GDSC1; GDSC2; CTRP2; CCLE 6.5402 7.1053 6.507 4.4463
SUIT-2 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.548 7.582 6.3665 4.9156
PSN1 GDSC1; GDSC2; CTRP2; CCLE 6.5636 7.2677 6.4918 4.4296
Panc 04.03 GDSC1; GDSC2; CTRP2; CCLE 6.6676 7.1904 6.6264 3.6713
TCC-Pan2 CTRP2 6.6748 9.4703 5.6184 7.9127
SW1990 GDSC1; GDSC2; CTRP2; CCLE 6.6787 10.1785 5.2737 8.8369
Panc 03.27 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.7152 7.7221 6.4852 4.0503
Panc 02.03 GDSC1; GDSC2; CTRP2; CCLE 6.7265 7.2484 6.6752 3.3349
DAN-G GDSC1; GDSC2; CTRP2 6.7523 7.3516 6.6707 3.4632
PaTu 8902 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.9472 7.4595 6.8379 2.1585
YAPC GDSC1; GDSC2; CTRP2 6.959 7.7492 6.7199 2.7213
L3.3 CTRP2; CCLE 7.089 10.6492 5.4007 7.5254
PK-59 CTRP2; CCLE 7.2724 12.2537 4.7526 9.7506
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 78 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 11.1715 29.2887 -0.7128 21.231
G-mel GDSC1; GDSC2 1.2322 3.5833 0.9649 22.3887
MZ-MEL-2 GDSC1; GDSC2 1.5441 5.5446 0.5218 23.4782
CP50-MEL-B GDSC1; GDSC2 2.0283 5.0967 1.2137 17.6289
WM35 GDSC1; GDSC2 2.6791 5.9079 1.4607 13.3448
A-375 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 2.8098 6.4174 2.6011 28.509
HT-144 GDSC1; GDSC2; CTRP2; CCLE 3.1386 5.8535 3.0515 26.0475
WM115 GDSC1; GDSC2; CTRP2; CCLE 3.2599 6.2165 3.1259 25.4362
MZ-MEL-7 GDSC1; GDSC2 3.5184 5.4997 2.3921 5.3398
WM266-4 CTRP2; CCLE 3.5229 5.5617 3.4893 23.4543
VMRC-MELG GDSC2 3.549 14.0518 -1.8549 26.7479
Hs 938.T GDSC1; GDSC2; CCLE 3.8082 8.975 0.8897 11.5965
HMV-II GDSC1; GDSC2 3.9236 9.7397 0.5996 14.6601
K029AX CTRP2; CCLE 3.928 7.3194 3.6014 21.8761
Mel Ho GDSC1; GDSC2; CTRP2; CCLE 3.9308 6.9806 3.6942 21.5542
WM1799 CTRP2; CCLE 3.9429 7.3761 3.6015 21.8328
G-361 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 3.9738 6.8278 3.7774 21.1485
WM88 CTRP2; CCLE 4.0535 7.2809 3.7491 21.0116
COLO 679 GDSC1; GDSC2; CCLE 4.0787 7.7805 1.6876 6.9417
WM278 GDSC1; GDSC2 4.0815 9.6101 0.7863 13.2386
Hs 294T CTRP2; CCLE 4.1042 6.5463 3.978 20.094
Mel JuSo GDSC1; GDSC2; CTRP2 4.1109 7.7084 3.684 22.2573
MMAc-SF GDSC1; GDSC2 4.1271 7.7563 1.7347 7.9121
A-388 GDSC1; GDSC2 4.2094 6.2892 2.4966 3.1383
LOX-IMVI GDSC1; GDSC2; CTRP2; CCLE 4.2116 9.9038 2.9554 23.3274
Hs 688(A).T CTRP2 4.2147 9.9617 2.934 24.6642
SH-4 GDSC1; GDSC2 4.2433 9.548 0.9394 11.9891
GAK GDSC1; GDSC2 4.2871 6.6711 2.3671 3.6303
WM1552C GDSC1; GDSC2 4.344 7.0476 2.2265 4.325
M14 GDSC1; GDSC2 4.4695 5.7381 2.8834 0.7209
WM793 GDSC1; GDSC2; CTRP2; CCLE 4.47 9.4742 3.4058 21.0762
Malme-3M CCLE 4.4843 8.0913 1.5595 4.7883
COLO 783 GDSC1; GDSC2 4.4887 6.2586 2.6741 1.7056
Hs 852.T CTRP2; CTRP1; CCLE 4.5187 8.7343 3.7574 19.6959
SF8657 CCLE 4.6899 6.6704 2.3086 1.1046
DJM-1 GDSC1; GDSC2 4.8473 7.9692 2.1129 4.1876
COLO 792 GDSC1; GDSC2; CTRP2 4.8502 8.6691 4.1351 18.4463
RPMI-7951 GDSC1; GDSC2; CTRP2; CCLE 4.8812 6.7409 4.7817 15.113
CP66-MEL GDSC1; GDSC2 5.0116 6.2076 2.9326 0.2397
COLO 741 CTRP1; CCLE 5.0353 6.3775 4.4746 3.7296
SK-MEL-5 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.2664 6.8211 5.1832 12.6333
SK-MEL-24 GDSC1; GDSC2; CTRP2; CCLE 5.2701 9.422 4.2571 15.9465
A-431 GDSC1; GDSC2 5.2794 7.3853 2.5974 1.173
Hs 940.T GDSC1; GDSC2; CTRP2 5.3243 7.509 5.0676 13.5852
UACC-257 GDSC1; GDSC2; CTRP2; CCLE 5.4769 9.6286 4.3754 14.9988
SK-MEL-31 GDSC1; GDSC2; CTRP2; CCLE 5.4818 9.4399 4.4651 14.6507
Hs 695T CCLE 5.4996 9.3752 1.5756 3.2831
LB2518-MEL GDSC1; GDSC2 5.5573 13.5646 -0.0773 14.5625
WM983B CTRP2; CCLE 5.559 7.5604 5.3062 11.3715
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 5.6932 8.3974 5.1347 12.288
451Lu GDSC1; GDSC2 5.7425 7.6433 2.6963 0.5135
Hs 944.T CTRP2; CTRP1; CCLE 5.8009 7.9039 5.4454 10.2194
LB373-MEL-D GDSC1; GDSC2 5.8114 13.093 0.3229 12.0863
IST-MEL1 GDSC1; GDSC2 5.8119 7.6135 2.7341 0.3736
CHL-1 GDSC1; GDSC2; CCLE 5.8133 7.851 2.6481 0.5107
Hs 936.T CTRP2; CTRP1; CCLE 5.8323 11.4651 3.8581 16.1289
RVH-421 GDSC1; GDSC2; CTRP2; CCLE 6.0429 9.7983 4.8588 11.8327
IGR-37 GDSC1; GDSC2; CTRP2; CCLE 6.238 7.0455 6.1915 6.3936
UACC-62 GDSC1; GDSC2; CCLE 6.2767 15.865 -0.6907 13.8083
IGR-1 GDSC1; GDSC2; CTRP2 6.2833 10.599 4.7029 12.5731
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 6.3436 6.89 6.3299 5.9378
COLO 800 GDSC1; GDSC2; CTRP2 6.3465 7.5171 6.1742 6.4919
MeWo GDSC1; GDSC2; CTRP2; CCLE 6.3529 7.3616 6.2336 5.9185
Hs 895.T CTRP2; CCLE 6.4272 8.1133 6.0183 6.5079
CJM [Human melanoma] CTRP2 6.433 12.2666 4.0194 15.0119
MDA-MB-435S CTRP2; CCLE 6.4723 11.2706 4.5474 12.1112
A101D GDSC1; GDSC2; CTRP2 6.509 12.3125 4.0647 14.6654
HMCB CTRP2; CCLE 6.5571 7.0567 6.5345 4.3049
IPC-298 GDSC1; GDSC2; CTRP2; CCLE 6.5586 7.1039 6.5273 4.3243
SK-MEL-3 GDSC1; GDSC2; CTRP2 6.5707 7.1759 6.5244 4.5409
SK-MEL-30 GDSC1; GDSC2; CTRP2; CCLE 6.5943 7.1558 6.5548 4.1268
IGR-39 CTRP2; CCLE 6.7098 7.4682 6.5828 3.7067
A2058 GDSC1; GDSC2; CTRP2; CCLE 6.7582 7.1179 6.7406 3.0219
SK-MEL-2 GDSC1; GDSC2; CTRP2; CCLE 6.7639 7.137 6.7432 2.9964
Hs 839.T CTRP2 6.8177 7.4938 6.6877 3.2141
COLO 829 GDSC1; GDSC2; CTRP2 7.3499 16.5495 2.669 18.1774
WT2-iPS GDSC1; GDSC2; CTRP2; CCLE 7.5351 13.238 4.4755 10.3658
EquiPSC Line K2 GDSC1; GDSC2 6.0635 15.3223 -0.5756 15.7298
⏷ Show the Full List of 78 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC1; GDSC2 5.1438 7.8217 2.3476 2.474
KYSE-50 GDSC1; GDSC2 5.2483 6.9362 2.7588 0.5849
ESO-51 GDSC1; GDSC2 5.3777 7.1083 2.7476 0.5432
OACP4 C GDSC1; GDSC2 5.4655 8.8265 2.0841 3.269
SK-GT-4 GDSC1; GDSC2 5.4956 9.0396 2.0069 3.615
FLO-1 GDSC1; GDSC2 5.5845 8.6378 2.2286 2.4194
KYSE-220 GDSC1; GDSC2 5.671 7.7199 2.6388 0.702
KYAE-1 GDSC1; GDSC2 5.6915 7.1445 2.8544 0.1762
OACM5.1 C GDSC1; GDSC2 5.8707 8.0291 2.605 0.6878
ESO-26 GDSC1; GDSC2 5.9621 7.6001 2.7945 0.207
TE-12 GDSC1; GDSC2 6.8089 13.3136 0.846 7.6609
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 5.3786 8.5818 4.7284 14.7166
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CCLE 1.2236 5.5755 0.0423 20.9579
CHP-134 GDSC1; GDSC2 1.3736 3.5241 1.1371 20.1567
KP-N-RT-BM-1 GDSC2 1.3862 4.0045 0.9904 21.5613
NB69 GDSC1; GDSC2 1.6196 4.4166 1.0823 19.419
CHP-212 GDSC1; GDSC2; CTRP2; CCLE 1.7082 4.719 1.6603 34.9281
MHH-NB-11 GDSC1; GDSC2; CTRP2 1.7167 3.7255 1.7123 36.7013
NH-12 GDSC1; GDSC2 1.8387 3.8119 1.5472 15.9493
CHP-126 GDSC1; GDSC2; CTRP2 1.8658 4.434 1.8423 35.7714
SJNB-17 GDSC1; GDSC2 1.9835 4.1591 1.5705 15.7162
IMR-5 GDSC1; GDSC2 2.0045 3.8875 1.698 14.4291
SJNB-10 GDSC1; GDSC2 2.0643 4.7316 1.4132 15.8025
GOTO GDSC1; GDSC2 2.1667 4.2859 1.7112 13.7024
SK-N-SH GDSC1; GDSC2; CTRP2; CCLE 2.2035 5.4635 2.1064 31.9648
SiMa GDSC1; GDSC2; CTRP2; CCLE 2.2501 4.7145 2.2239 31.4494
SJNB-5 GDSC1; GDSC2 2.7857 5.9907 1.5179 13.0602
KP-N-SI9s CTRP2; CCLE 2.8861 5.1042 2.8591 27.4455
SJNB-12 GDSC1; GDSC2 2.9708 5.7086 1.8247 10.2182
GI-ME-N GDSC1; GDSC2 2.9824 6.7206 1.332 13.1483
LA-N-6 GDSC1; GDSC2 2.9977 6.9035 1.2542 13.9872
NH-6 CTRP2 3.1703 4.1295 3.1702 27.0125
SK-N-DZ GDSC1; GDSC2; CTRP2; CCLE 4.0538 5.1191 4.0525 20.0071
SJNB-7 GDSC1; GDSC2 4.2652 6.2303 2.5584 2.5984
SJNB-14 GDSC1; GDSC2 4.3117 6.1864 2.6063 2.2613
NB(TU)1 GDSC1; GDSC2 4.4186 7.5663 2.0295 5.3134
SK-N-MC-IXC GDSC1; GDSC2 4.4219 6.6024 2.4824 2.8407
SJNB-6 GDSC1; GDSC2 4.5891 6.4449 2.6472 1.7066
TGW GDSC1; GDSC2 5.0109 6.7653 2.7217 0.8839
NB1 GDSC1; GDSC2; CTRP2 5.1468 8.3822 4.5632 15.9894
Kelly GDSC1; GDSC2; CTRP2; CCLE 5.3204 7.0235 5.1984 12.4229
SJNB-13 GDSC1; GDSC2 5.4805 7.1451 2.7752 0.4144
SK-N-BE(2)-M17 GDSC1; GDSC2 5.634 7.3718 2.7527 0.4026
KP-N-YS GDSC1; GDSC2 5.7266 7.8106 2.6277 0.7257
SK-N-AS GDSC1; GDSC2; CTRP2; CCLE 5.8173 6.8764 5.7683 9.0509
SK-N-FI GDSC1; GDSC2; CCLE 5.9426 7.5191 2.8153 0.1535
KP-N-YN GDSC1; GDSC2; CTRP2 6.3298 10.617 4.7375 12.3257
SK-N-BE(2) CTRP2; CCLE 6.4866 7.4428 6.3517 5.134
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 1.9902 5.3633 1.8922 35.1809
HuH-28 CTRP2 5.5834 7.4616 5.3646 11.7261
SNU-478 CTRP2 6.1148 7.0591 6.0548 7.6211
SNU-308 CTRP2 6.3753 7.3222 6.2703 6.0516
SNU-1196 CTRP2 6.4766 7.2819 6.3928 5.301
SNU-869 CTRP2 6.5342 7.3731 6.427 5.0051
HuCC-T1 GDSC1; GDSC2; CTRP2; CCLE 6.5723 7.2302 6.512 4.3358
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1; GDSC2; CTRP2 1.3242 3.385 1.3208 39.3104
CAL-148 GDSC2; CTRP2 2.2803 6.0306 2.1019 33.5142
HCC1500 GDSC1; GDSC2; CTRP2 3.186 4.5473 3.1842 26.9139
MCF-7 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 3.3961 8.0756 2.7875 26.1532
MRK-nu-1 GDSC1; GDSC2 3.4325 7.5564 1.2961 12.0458
KPL-1 CTRP2 3.4419 5.6098 3.4003 34.5345
CAL-51 GDSC1; GDSC2; CTRP2 3.7873 6.7163 3.5995 23.551
YMB-1-E GDSC2 3.804 7.6035 1.5684 9.7362
HCC1599 GDSC2 4.1319 6.3005 2.4415 3.5997
HCC2157 GDSC1; GDSC2 4.3284 6.2879 2.5701 2.4295
HCC1569 GDSC1; GDSC2; CCLE 4.4345 6.863 2.3704 2.8769
MDA-MB-175-VII GDSC1; GDSC2; CCLE 4.5095 8.2758 1.7512 5.8033
Hs 578T GDSC1; GDSC2; CTRP2; CCLE 4.6226 6.8099 4.4871 16.8609
MDA-MB-468 GDSC1; GDSC2; CTRP2; CCLE 4.6948 6.2778 4.6533 16.0971
HCC2218 GDSC1; GDSC2; CTRP2 4.7747 8.0149 4.3011 18.0341
COLO 824 GDSC1; GDSC2 4.8062 6.7711 2.6208 1.5136
MDA-MB-330 GDSC1; GDSC2 4.8355 7.9213 2.1277 4.1105
HCC1187 GDSC1; GDSC2; CCLE 4.8402 7.1087 2.494 1.7846
ZR-75-1 CTRP2; CCLE 5.0734 10.0404 3.7816 18.1892
MDA-MB-453 GDSC1; GDSC2; CTRP2; CCLE 5.1908 7.0334 5.0549 13.2852
AU565 GDSC1; GDSC2; CTRP2; CCLE 5.1952 7.3416 4.9776 13.5356
CAL-85-1 GDSC1; GDSC2; CTRP2; CCLE 5.2064 6.9435 5.0925 13.1131
HCC70 GDSC1; GDSC2; CCLE 5.3535 7.1694 2.7144 0.5673
EFM-19 GDSC1; GDSC2; CCLE 5.3546 7.3332 2.6518 0.749
UACC-812 GDSC2; CTRP2; CCLE 5.3662 10.6882 3.7775 17.4988
MFM-223 GDSC1; GDSC2 5.4285 6.8472 2.8621 0.2359
Evsa-T GDSC1; GDSC2 5.444 6.8728 2.8589 0.2374
UACC-893 GDSC1; GDSC2 5.4867 7.9025 2.4856 1.4366
Hs 739.T CCLE 5.5186 9.2291 1.6494 2.9405
BT-483 GDSC1; GDSC2 5.6429 10.051 1.6383 5.2965
MDA-MB-157 GDSC1; GDSC2; CTRP2; CCLE 5.7347 8.1868 5.2642 11.0503
HCC1143 GDSC1; GDSC2; CTRP2 5.7956 8.2841 5.2889 11.4124
HCC1395 GDSC1; GDSC2; CTRP2; CCLE 5.8343 7.8961 5.4841 9.9911
HMC-1-8 CTRP2; CCLE 5.88 6.6053 5.8691 8.5321
OCUB-M GDSC1; GDSC2 5.9931 7.853 2.7173 0.3434
HCC38 GDSC1; GDSC2; CTRP2 6.0317 7.6071 5.8025 8.791
MDA-MB-436 GDSC1; GDSC2; CCLE 6.0662 7.7149 2.7922 0.1597
EFM-192A GDSC1; GDSC2; CTRP2 6.0727 7.4738 5.8927 8.3359
HCC1954 GDSC1; GDSC2; CTRP2; CCLE 6.079 8.7774 5.368 9.8033
ZR-75-30 GDSC1; GDSC2; CTRP2; CCLE 6.118 8.9215 5.3418 9.8097
HCC202 GDSC1; GDSC2; CTRP2 6.1336 8.0194 5.7529 8.6958
SK-BR-3 CTRP2; CCLE 6.163 7.7181 5.9032 7.608
CAL-120 GDSC1; GDSC2; CTRP2 6.2497 7.1533 6.1799 6.7589
BT-474 GDSC1; GDSC2; CTRP2; CCLE 6.3587 7.267 6.2685 5.7814
BT-20 GDSC1; GDSC2; CTRP2; CCLE 6.3604 7.863 6.0556 6.5375
BT-549 GDSC1; GDSC2; CTRP2; CCLE 6.3712 7.1549 6.312 5.5976
HCC1428 GDSC1; GDSC2; CTRP2 6.4005 7.3786 6.2799 5.9415
Hs 578Bst CTRP2 6.4112 9.3789 5.4145 9.3571
HCC1806 GDSC1; GDSC2; CTRP2; CCLE 6.4569 12.9837 3.6852 15.4454
MDA-MB-361 GDSC1; GDSC2; CTRP2 6.5054 7.4736 6.3611 5.3342
MDA-MB-231 GDSC1; GDSC2; CTRP2 6.5371 7.7678 6.2803 5.5558
HCC1419 GDSC1; GDSC2; CTRP2 6.5937 7.4781 6.4546 4.7301
HCC1937 GDSC1; GDSC2; CTRP2 6.5973 7.5272 6.4401 4.7748
JIMT-1 GDSC1; GDSC2; CTRP2 6.602 7.1104 6.573 4.2715
MDA-MB-415 GDSC1; GDSC2; CTRP2; CCLE 6.6268 7.2325 6.5708 3.9783
HDQ-P1 GDSC1; GDSC2; CTRP2; CCLE 6.6497 7.8626 6.3566 4.6931
T-47D GDSC1; GDSC2; CTRP2; CCLE 6.6813 11.549 4.597 11.4916
CAMA-1 GDSC1; GDSC2; CTRP2; CCLE 6.7935 7.9864 6.4458 4.0102
BT 271 CTRP2 0.2375 5.0882 0.0589 46.7574
BT 239 CTRP2 0.8991 4.3247 0.8462 42.2673
BT 330 CTRP2 1.17 6.2703 0.8515 41.1009
BT 504 CTRP2 1.414 5.9656 1.1778 39.3494
BT 286 CTRP2 1.5834 5.9207 1.3694 38.1928
BT164 CTRP2 1.8485 3.6734 1.846 35.8182
BT 112 CTRP2 2.0307 5.1176 1.9629 34.8168
BT 139 CTRP2 2.8708 5.9397 2.7527 29.4026
BT 131 CTRP2 2.8739 6.5776 2.6368 29.782
BT 145 CTRP2 2.9914 4.9537 2.976 28.2542
BT147 CTRP2 3.2296 6.7902 2.9759 27.483
BT 172 CTRP2 3.2554 7.1476 2.9144 27.6122
BT 440 CTRP2 3.3474 8.0271 2.7509 27.8817
BT 416 CTRP2 3.5847 4.3168 3.5847 24.254
BT 228 CTRP2 3.6092 6.0055 3.5329 24.3493
BT 428 CTRP2 3.8247 6.629 3.6588 23.2259
BT 340 CTRP2 4.122 8.9031 3.2694 23.7314
BT 232 CTRP2 4.868 10.4113 3.4068 21.1597
BT 231 CTRP2 5.5371 7.5353 5.2906 12.1351
BT 216 CTRP2 5.7423 9.8743 4.5281 14.5662
BT 159 CTRP2 6.1102 6.7798 6.0951 7.496
BT 245 CTRP2 6.2298 19.6161 0.1841 27.7011
BT 422 CTRP2 6.2353 7.2414 6.1411 6.942
BT 498 CTRP2 6.2537 10.4191 4.7626 12.3961
BT 482 CTRP2 6.3342 8.1494 5.9069 7.5582
BT 224 CTRP2 6.3521 9.2979 5.3963 9.5712
BT 179 CTRP2 6.4251 7.0362 6.3958 5.4496
BT 359 CTRP2 6.4712 7.5544 6.2948 5.6819
BT 320 CTRP2 6.5504 7.0473 6.5289 4.5887
BT 333 CTRP2 6.615 7.1417 6.5806 4.2041
BT 328 CTRP2 6.6297 7.1598 6.5925 4.1161
BT 248 CTRP2 6.6546 11.871 4.4134 12.9431
BT 444 CTRP2 7.1205 24.459 -1.4767 29.3791
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.4924 7.2669 6.4145 5.1749
Cancer Drug Sensitivity Data Curated from 70 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC1; GDSC2; CCLE 0.7407 4.801 -0.0021 24.8892
D283 Med GDSC1; GDSC2; CTRP2 1.7908 4.3336 1.7699 36.2618
D-502MG GDSC1; GDSC2 1.8864 5.8474 0.7274 20.9815
D-247MG GDSC1; GDSC2 2.1112 7.1251 0.3365 22.2554
SNU-466 CTRP2 2.1661 3.828 2.1642 33.7022
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 2.3895 6.3388 0.9801 17.1289
A-172 GDSC1; GDSC2; CTRP2; CCLE 2.717 6.3377 2.5165 29.0653
KNS-81-FD GDSC1; GDSC2 3.1639 6.2681 1.7151 10.6287
D-392MG GDSC1; GDSC2 3.192 7.2301 1.2586 12.9549
DK-MG GDSC1; GDSC2; CTRP2; CCLE 3.2013 7.8223 2.6581 27.148
CCF-STTG1 CTRP2 3.2772 5.7435 3.2126 26.5185
D-245MG GDSC2 3.5864 9.9284 0.2364 17.9551
LNZTA3WT4 GDSC1; GDSC2 4.282 6.068 2.6425 2.1832
AM-38 GDSC1; GDSC2; CTRP2 4.4511 9.5516 3.3536 22.4892
Onda 10 GDSC1; GDSC2 4.5734 8.7967 1.5443 8.0385
1321N1 CCLE 4.7012 8.4001 1.5517 4.4827
Hs 683 GDSC1; GDSC2; CTRP2; CCLE 4.7431 6.4979 4.675 15.8795
CAS-1 GDSC1; GDSC2; CTRP2; CCLE 4.8814 5.9484 4.8738 14.813
PFSK-1 GDSC1; GDSC2 4.9118 8.1139 2.0855 4.0986
ONS-76 GDSC1; GDSC2; CTRP2; CCLE 4.9404 9.4121 3.9216 18.008
LN-405 GDSC1; GDSC2 5.0585 6.5033 2.8431 0.4402
D-423MG GDSC1; GDSC2 5.065 7.572 2.4135 2.2486
DBTRG-05MG GDSC1; GDSC2; CTRP2; CCLE 5.1226 10.7056 3.528 18.9972
D-566MG GDSC1; GDSC2 5.1963 8.0936 2.2577 2.8592
LN-229 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.2876 7.0277 5.1616 12.6427
D-263MG GDSC1; GDSC2 5.3081 6.8055 2.8313 0.3499
SW1783 GDSC1; GDSC2; CTRP2 5.3429 7.2376 5.1682 13.1628
KNS-81 CTRP2; CCLE 5.4711 8.9506 4.6693 13.9144
SK-MG-1 GDSC1; GDSC2 5.5188 7.0171 2.8358 0.2593
SF268 GDSC1; GDSC2; CTRP2 5.5224 6.6473 5.4871 11.4771
SNU-626 CTRP2 5.6204 7.7313 5.3146 11.8035
GI-1 GDSC1; GDSC2; CCLE 5.6268 8.2353 2.4168 1.3303
SF539 GDSC1; GDSC2; CTRP2 5.7059 6.8153 5.6588 10.2965
GOS-3 CTRP2 5.736 9.9888 4.4685 14.8204
D-542MG GDSC1; GDSC2 5.7664 7.4051 2.791 0.2771
Onda 11 GDSC1; GDSC2 5.7694 7.8682 2.6237 0.7122
NMC-G1 GDSC1; GDSC2; CTRP2 5.7995 9.9314 4.5579 14.3058
KNS-60 CTRP2; CCLE 5.8999 6.7419 5.8767 8.4463
LN-18 GDSC1; GDSC2; CTRP2; CCLE 5.9107 6.353 5.9102 8.306
MOG-G-CCM GDSC1; GDSC2; CCLE 5.9237 8.0136 2.6323 0.4996
M059J GDSC1; GDSC2; CCLE 5.9973 7.67 2.783 0.1866
GB-1 GDSC1; GDSC2; CTRP2; CCLE 6.1953 8.5264 5.5985 8.6522
Daoy GDSC1; GDSC2; CTRP2; CCLE 6.2113 8.6609 5.5542 8.781
SNU-738 CTRP2 6.2774 7.0561 6.232 6.4883
SNU-201 CTRP2 6.3035 7.4467 6.1521 6.699
GMS-10 CTRP2; CCLE 6.341 7.5411 6.1597 6.2117
KG-1-C CTRP2 6.3771 9.2143 5.4602 9.2506
42-MG-BA GDSC1; GDSC2; CTRP2; CCLE 6.3821 9.1005 5.5191 8.5179
KNS-42 GDSC1; GDSC2; CTRP2; CCLE 6.4142 7.8257 6.1274 6.1355
D-336MG GDSC1; GDSC2 6.4157 8.7645 2.5518 0.5779
TM-31 CTRP2 6.4214 7.0405 6.391 5.4781
U-118MG GDSC1; GDSC2; CTRP2; CCLE 6.441 7.8933 6.1274 6.0674
SF126 GDSC1; GDSC2; CTRP2; CCLE 6.4567 9.1386 5.5732 8.1406
M059K CTRP2 6.4653 7.0755 6.4319 5.1963
U-251MG GDSC1; GDSC2; CTRP2 6.4811 7.2248 6.4139 5.2111
SF295 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.4864 7.421 6.359 5.1083
MOG-G-UVW GDSC1; GDSC2 6.5031 8.3062 2.7447 0.1636
YH-13 GDSC1; GDSC2; CTRP2 6.5726 7.18 6.5254 4.5312
SNU-489 CTRP2 6.6273 7.1713 6.5871 4.1427
SW1088 GDSC1; GDSC2; CTRP2; CCLE 6.6431 7.4298 6.5253 4.0913
KINGS-1 GDSC1; GDSC2 6.6597 8.7116 2.6616 0.251
YKG-1 GDSC1; GDSC2; CTRP2; CCLE 6.6974 7.2134 6.653 3.4942
T98G GDSC1; GDSC2; CTRP2; CCLE 6.727 7.3416 6.6467 3.4325
GaMG CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.7854 7.239 6.7421 2.9373
U-87MG ATCC GDSC1; GDSC2; CTRP2; CCLE 6.7883 13.0592 3.9388 13.8242
8-MG-BA GDSC1; GDSC2; CTRP2; CCLE 6.828 7.5275 6.6848 3.0265
Becker GDSC1; GDSC2; CTRP2 6.8465 10.1663 5.4305 8.3222
SNB-75 GDSC1; GDSC2; CTRP2 8.3696 11.8567 5.7827 4.1928
KALS-1 GDSC1; GDSC2; CTRP2; CCLE 9.2674 15.9256 4.4397 7.8202
SNU-1105 CTRP2 10.8742 23.7399 1.7785 15.1658
⏷ Show the Full List of 70 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1; GDSC2 5.3629 6.9143 2.8132 0.371
TGBC24TKB GDSC1; GDSC2 6.0437 8.2156 2.6058 0.5934
ETK-1 GDSC1; GDSC2 6.1657 8.1969 2.6601 0.4053
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1; CCLE -0.1828 2.1863 -0.1851 46.6988
JHUEM-7 CTRP2 2.5816 4.9005 2.5561 31.0157
JHUEM-1 CTRP2 3.4468 4.453 3.4466 25.1726
HEC-151 CTRP2; CTRP1; CCLE 4.2261 5.7157 4.2101 18.9683
HEC-265 CTRP2; CTRP1; CCLE 4.8995 6.4787 4.8454 14.8487
RL95-2 GDSC1; GDSC2; CTRP2; CCLE 5.066 7.3572 4.8322 14.4037
HEC-1-B CTRP2; CCLE 5.1654 7.5633 4.8775 13.9662
TEN CCLE 5.3782 7.2289 2.3915 0.4173
MFE-319 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.4409 6.9389 5.3484 11.5655
HEC-108 CTRP2; CTRP1 5.6824 9.7199 4.5401 14.6676
HEC-1-A CTRP2; CCLE 5.8404 8.5512 5.2233 10.9316
HEC-59 CTRP2; CTRP1; CCLE 6.111 8.1944 5.6563 8.6447
JHUEM-3 CTRP2 6.1457 7.6767 5.9001 8.0979
HEC-6 CTRP2; CTRP1; CCLE 6.1915 9.3771 5.2026 10.1711
MFE-280 GDSC1; GDSC2; CCLE 6.2361 8.3298 2.6393 0.3655
EN GDSC1; GDSC2; CTRP2; CCLE 6.3933 7.9276 6.0632 6.4256
MFE-296 GDSC1; GDSC2; CTRP2; CCLE 6.5043 10.236 5.0856 9.9394
HEC-251 CTRP2; CTRP1; CCLE 6.5137 9.4909 5.4579 8.4632
ESS-1 GDSC1; GDSC2; CTRP2; CCLE 6.6837 7.2185 6.6367 3.5894
EFE-184 CTRP2; CCLE 6.6838 7.2773 6.6201 3.6461
KLE GDSC1; GDSC2; CTRP1; CCLE 6.8219 8.9014 4.471 1.1424
HEC-50B CTRP2 6.8986 7.9504 6.566 3.4932
AN3-CA GDSC1; GDSC2; CTRP2; CCLE 7.0525 11.243 5.0729 8.8937
Ishikawa (Heraklio) 02 ER- CTRP1; CCLE 5.2597 6.0386 4.836 1.5986
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HA7-RCC GDSC1; GDSC2 0.9932 3.0384 0.852 24.1019
KTCTL-140 GDSC1; GDSC2 1.6072 4.6894 0.9575 20.8023
TUHR14TKB CTRP2 1.853 5.0812 -1.9213 3.1882
LB996-RCC GDSC1; GDSC2 1.8579 4.4762 1.3087 17.1992
LB2241-RCC GDSC1; GDSC2 1.9649 4.0337 1.6 15.6239
KTCTL-21 GDSC1; GDSC2 2.6434 5.3358 1.7057 12.3867
CAL-54 GDSC1; GDSC2; CTRP2 2.7801 6.4626 2.5595 30.3472
SW156 GDSC1; GDSC2 3.0538 6.658 1.4255 12.7654
UO-31 GDSC1; GDSC2; CTRP2 3.1896 6.4747 3.0014 27.5235
KTCTL-1M GDSC1; GDSC2 3.2488 6.0115 1.9157 9.1136
KTCTL-195 GDSC1; GDSC2 3.7299 7.6188 1.5033 10.0162
ACHN GDSC1; GDSC2; CTRP2; CCLE 4.3124 7.0078 4.1035 19.0597
A-704 GDSC1; GDSC2 4.3251 8.0693 1.7234 7.2918
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 4.3971 8.4298 3.7438 21.1979
SW13 GDSC1; GDSC2 4.6471 6.1435 2.8029 0.8841
769-P GDSC1; GDSC2; CTRP2; CCLE 4.6902 9.0199 3.8247 19.0029
NCC021 GDSC1; GDSC2 4.8384 7.5046 2.3184 3.0674
RXF 393L GDSC1; GDSC2 4.8523 11.6042 0.3766 13.9187
A-498 GDSC1; GDSC2 4.8787 10.5279 0.9195 10.637
KMRC-3 CTRP2 5.5477 7.9415 5.16 12.5932
VMRC-RCW CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.5592 7.4762 5.3336 11.2753
SN12C GDSC1; GDSC2 5.5732 7.0424 2.847 0.2205
KMRC-1 GDSC1; GDSC2; CTRP2; CCLE 5.6549 10.9374 3.9417 16.2147
TK-10 GDSC1; GDSC2 5.7912 8.0404 2.5675 0.8541
NCC010 GDSC1; GDSC2 5.8624 7.9459 2.6326 0.6316
SNU-1272 CTRP2 6.0804 8.5533 5.4694 9.9495
BFTC-909 GDSC1; GDSC2; CTRP2; CCLE 6.0927 7.1431 6.0113 7.425
KTCTL-26A GDSC1; GDSC2 6.0964 8.356 2.5751 0.6725
BB65-RCC GDSC1; GDSC2 6.126 7.8377 2.7714 0.2108
KMRC-20 GDSC1; GDSC2; CTRP2 6.4472 7.094 6.4085 5.335
LB1047-RCC GDSC1; GDSC2 6.4654 8.4044 2.6978 0.2478
VMRC-RCZ GDSC1; GDSC2; CTRP2; CCLE 6.4928 7.2699 6.414 4.8992
Caki-2 CTRP2; CCLE 6.4962 9.9853 5.2008 9.5054
KTCTL-13 GDSC1; GDSC2 6.4983 8.1924 2.7813 0.1247
TUHR4TKB CTRP2 6.5457 7.2363 6.4813 4.7719
786-O GDSC1; GDSC2; CTRP2; CCLE 6.5681 7.2642 6.4978 4.3962
TUHR10TKB CTRP2 6.6316 7.1635 6.5937 4.1058
OS-RC-2 GDSC1; GDSC2; CTRP2 6.6435 11.4643 4.6055 12.1789
KMRC-2 CTRP2; CCLE 7.5372 12.6187 4.7863 9.1472
Caki-1 GDSC1; GDSC2; CTRP2 7.7675 13.5296 4.5153 10.3517
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 GDSC2; CTRP2; CTRP1 1.5902 4.6971 1.5388 37.6893
SW48 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 1.8967 3.9176 1.8912 33.6104
LoVo GDSC1; GDSC2; CTRP2; CTRP1 2.095 5.575 1.9757 34.5532
LS513 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 2.1806 5.5987 2.0639 32.1698
LS180 GDSC1; GDSC2; CTRP2; CTRP1 2.3689 6.1897 2.1683 32.9994
HCT 116 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 2.4159 6.6933 2.1123 31.2741
GP5d GDSC1; GDSC2 2.7616 5.6614 1.6577 11.8949
GP2d CTRP1 2.9565 5.2901 2.7282 33.7288
SK-CO-1 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 2.977 5.1006 2.9535 26.8613
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 2.9931 4.9532 2.9778 28.2428
SNU-407 GDSC1; GDSC2; CTRP2 3.2464 6.0214 3.1428 26.8564
SNU-1040 GDSC2; CTRP1 3.5698 6.5284 3.4005 26.832
CCK-81 GDSC1; GDSC2; CTRP2; CCLE 3.757 6.8136 3.5447 22.5657
COLO 320HSR GDSC1; GDSC2 4.3069 6.1525 2.6188 2.2021
COLO 678 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.791 9.7674 3.6138 19.5056
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 4.8313 10.2026 3.4632 21.046
SW1116 GDSC1; GDSC2 4.8798 6.4981 2.7683 0.8152
RKO CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.9778 8.1922 4.4553 15.9731
SNU-81 GDSC1; GDSC2; CTRP1 5.1143 6.1746 5.1019 15.1316
SW626 GDSC1; GDSC2 5.1163 7.4358 2.4979 1.7219
SW480 CTRP1; CCLE 5.1772 6.7048 5.1062 13.0489
SNU-C4 CTRP2; CTRP1 5.2514 7.0267 5.1225 13.6072
NCI-H508 GDSC1; GDSC2; CTRP2; CTRP1 5.3003 6.7529 5.2323 13.0678
C2BBe1 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.3074 7.7597 4.9661 13.2621
HCC2998 GDSC1; GDSC2 5.3546 7.6591 2.522 1.3713
SW1417 GDSC1; GDSC2; CTRP2; CCLE 5.3661 7.198 5.2044 12.2694
SW948 GDSC1; GDSC2; CTRP2; CTRP1 5.4393 6.9688 5.3402 12.2522
DiFi GDSC1; GDSC2 5.4603 8.1223 2.3826 1.8607
SW403 CTRP1; CCLE 5.5256 7.49 4.3208 3.4325
NCI-H747 GDSC1; GDSC2; CCLE 5.5413 8.2802 2.3571 1.6226
SW620 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.5669 6.9285 5.4874 10.7291
HCT 8 CTRP2; CTRP1 5.6093 7.162 5.4792 11.2322
SNU-C2B GDSC1; GDSC2; CCLE 5.6262 9.361 1.9376 3.255
HT115 GDSC1; GDSC2; CTRP2; CTRP1 5.6784 6.8513 5.6229 10.5086
NCI-H716 GDSC1; GDSC2; CTRP2 5.7021 8.4642 5.1162 12.3362
SNU-283 GDSC2 5.7679 7.927 2.6009 0.7861
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 5.8022 7.0497 5.7169 9.7895
SW1463 GDSC1; GDSC2; CTRP2 5.8171 8.1186 5.3788 11.0062
T84 GDSC1; GDSC2; CTRP2; CCLE 5.8497 7.3407 5.6918 9.2148
SNU-61 GDSC1; GDSC2; CTRP2; CTRP1 5.8548 7.1381 5.753 9.4987
CL-40 CTRP1 5.8712 9.2971 4.9138 26.4073
COLO 320 CTRP2; CTRP1; CCLE 5.8786 8.005 5.4891 9.856
SNU-C2A CTRP2; CTRP1; CCLE 5.8929 8.1628 5.4409 9.9948
SW837 GDSC1; GDSC2 5.9635 7.8026 2.7241 0.3394
SNU-1033 CTRP2 6.0424 9.8489 4.8344 12.5998
CL-34 CTRP1 6.1086 7.1823 6.0154 16.4235
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 6.1512 7.3762 6.0095 7.6739
SNU-C1 GDSC1; GDSC2; CTRP2 6.1726 8.0569 5.7783 8.4916
LS1034 GDSC1; GDSC2; CTRP2 6.2424 7.2457 6.1477 6.8966
HCT 15 GDSC1; GDSC2; CTRP2; CCLE 6.2778 7.3221 6.1641 6.3713
COLO205 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3143 7.5046 6.1439 6.3405
SNU-C5 GDSC1; GDSC2; CTRP2; CTRP1 6.3169 7.4302 6.1721 6.5856
DLD-1 CTRP2; CTRP1 6.3256 7.2747 6.2302 6.3463
CaR-1 GDSC1; GDSC2 6.3383 7.8679 2.8348 0.0883
LS411N CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3526 7.3772 6.2282 5.9382
LS123 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3669 7.206 6.2943 5.6697
HT-29 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3698 7.0746 6.3285 5.5459
OUMS-23 CTRP2 6.3931 7.3958 6.2663 6.0136
COLO201 CTRP2; CCLE 6.4632 7.6478 6.2506 5.5587
KM12 GDSC1; GDSC2; CTRP2; CTRP1 6.575 7.361 6.4753 4.7065
SNU-503 CTRP2 6.5821 7.2275 6.5234 4.5093
CL-11 GDSC1; GDSC2; CTRP2 6.7207 7.7036 6.4988 4.2112
HCC-56 CTRP2; CCLE 6.7558 7.1173 6.7382 3.037
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 3.4858 6.8373 1.6989 9.487
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2/C3A GDSC1; GDSC2; CCLE 3.819 6.8567 1.9497 6.1161
Hep-G2 CTRP2; CTRP1; CCLE 4.2975 7.9265 3.8153 20.0932
SNU-878 CTRP2 4.3727 7.2564 4.1043 19.9476
SNU-182 CTRP2; CCLE 4.5048 7.2705 4.2446 18.0235
Li-7 CTRP2 4.7615 9.2272 3.8138 19.9118
SK-HEP-1 GDSC1; GDSC2; CTRP2; CCLE 4.9025 9.1605 3.9891 17.8582
Huh-7 GDSC1; GDSC2 4.9516 8.4019 1.9774 4.6212
JHH-5 CTRP2; CCLE 4.9635 6.2242 4.9418 14.3408
JHH-7 GDSC1; GDSC2; CCLE 5.0455 7.4629 2.4501 1.7433
SNU-761 CTRP2 5.196 7.1747 5.0249 14.1265
SNU-398 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.3787 7.1223 5.2378 12.1194
JHH-1 GDSC1; GDSC2; CTRP2 5.5799 7.7243 5.2732 12.0753
SNU-449 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.587 7.1081 5.4685 10.733
HuH-1 GDSC1; GDSC2; CTRP2; CCLE 5.6376 7.2344 5.4907 10.5109
HLE GDSC1; GDSC2; CCLE 5.6891 7.4343 2.7515 0.3288
HLF CTRP2; CCLE 5.8436 9.3742 4.8598 12.2919
HuH-6 CTRP2 5.9604 7.7829 5.6617 9.5255
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2; CCLE 6.0285 7.0854 5.9551 7.8022
SNU-423 GDSC1; GDSC2; CTRP2; CCLE 6.2666 8.0212 5.8916 7.3807
JHH-2 GDSC1; GDSC2; CTRP2; CCLE 6.4048 8.5637 5.7927 7.4152
SNU-387 GDSC1; GDSC2; CTRP2; CCLE 6.4983 7.5893 6.3106 5.2491
PLC/PRF/5 CTRP2; CCLE 6.5173 9.543 5.4359 8.5412
SNU-475 CTRP2; CCLE 6.5404 7.5255 6.3799 4.8877
JHH-4 GDSC1; GDSC2; CTRP2; CCLE 6.5588 9.9982 5.2526 9.1696
JHH-6 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.9593 7.7237 6.732 2.529
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 228 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2073 CTRP1 1.4701 8.775 0.4579 65.0038
NCI-H290 GDSC1; GDSC2 2.0509 4.893 1.3281 16.8662
SBC-3 GDSC1; GDSC2 2.6598 5.2068 1.7834 11.48
NCI-H2795 GDSC1; GDSC2 2.6719 7.1622 0.8364 17.0031
NCI-H2122 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 2.7064 5.9167 2.5798 28.8954
A-427 GDSC1; GDSC2 2.8107 5.5468 1.7592 11.4816
NCI-H2373 GDSC1; GDSC2 2.9215 6.3784 1.4484 12.6423
HCC1588 CTRP2 2.9989 6.2746 2.8338 28.7107
NCI-H2722 GDSC1; GDSC2 3.0908 6.9428 1.3155 12.918
EMC-BAC-2 GDSC1; GDSC2 3.1644 8.561 0.57 16.9443
COLO 677 CCLE 3.3642 6.8843 1.3524 8.0537
Lu-99 CTRP2; CTRP1; CCLE 3.472 6.8694 3.2212 24.4869
DV-90 CTRP2; CTRP1; CCLE 3.6054 7.0232 3.3286 23.7349
NCI-H2803 GDSC2 3.7216 6.1052 2.2477 5.7233
NCI-H1341 GDSC1; GDSC2; CTRP2; CCLE 3.8077 4.3086 3.8077 21.5537
NCI-H1944 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 3.8194 8.057 3.2529 23.376
A-549 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 3.9389 6.965 3.7069 21.4875
NCI-H524 GDSC1; GDSC2 3.9484 6.0006 2.4619 3.7498
NCI-H847 GDSC1; GDSC2 3.9492 5.8318 2.5434 3.2702
NCI-H596 GDSC1; GDSC2; CTRP1 4.0089 5.2527 4.005 22.5935
Lu-135 GDSC1; GDSC2 4.0599 5.5814 2.7319 1.9924
NCI-H2066 GDSC1; GDSC2 4.0996 5.9897 2.5671 2.843
NCI-H1930 CTRP1 4.1886 9.3369 2.2435 28.7684
IST-SL2 GDSC1; GDSC2 4.252 6.1053 2.6077 2.3507
Ms-1 GDSC1; GDSC2 4.2535 5.8914 2.7054 1.8263
NCI-H2869 GDSC1; GDSC2 4.3192 10.1047 0.7215 13.3744
SW1573 GDSC1; GDSC2; CCLE 4.33 7.1562 2.1658 4.0434
NCI-H2369 GDSC1; GDSC2 4.3792 6.978 2.282 3.9419
Lu-99A GDSC1; GDSC2 4.4257 8.4479 1.6104 7.7312
CPC-N GDSC1; GDSC2 4.4494 7.7633 1.956 5.6762
NCI-H345 GDSC1; GDSC2 4.4662 5.2186 3.0786 0.1195
NCI-H1963 GDSC2; CTRP1 4.4671 6.009 4.4395 19.4454
LC-2/ad GDSC1; GDSC2 4.5154 6.9779 2.3669 3.331
NCI-H226 GDSC1; GDSC2; CTRP2; CCLE 4.5208 7.549 4.1802 18.1995
UMC-11 GDSC1; GDSC2 4.5233 6.7535 2.4738 2.6352
NCI-H1648 GDSC1; GDSC2; CCLE 4.5352 7.6037 2.088 4.0872
NCI-H810 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.5506 5.4979 4.5489 16.8784
NCI-H720 GDSC1; GDSC2 4.5709 7.0995 2.3446 3.2555
NCI-H2461 GDSC1; GDSC2 4.5891 9.6676 1.1331 10.0978
NCI-H835 GDSC1; GDSC2 4.6283 9.8662 1.0643 10.394
NCI-H2029 GDSC1; GDSC2; CTRP1 4.63 5.2347 4.57 5.1556
NCI-H2810 GDSC1; GDSC2 4.6348 8.5344 1.7119 6.9183
NCI-H187 GDSC1 4.6657 5.8219 2.6243 0.2717
COR-L279 GDSC1; GDSC2; CTRP1 4.6779 5.3549 4.584 4.781
SCLC-21H CTRP1 4.7099 6.215 4.6751 35.9452
NCI-H1568 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.7119 6.5061 4.6402 16.0878
NCI-H2731 GDSC1; GDSC2 4.7134 6.7395 2.586 1.7909
COLO 668 GDSC1; GDSC2; CTRP1 4.722 5.859 4.4237 5.4029
NCI-H1304 GDSC1 4.7507 6.437 2.4298 0.9331
NCI-H1437 GDSC1; GDSC2; CTRP1 4.7513 6.6544 4.0769 7.2508
NCI-H1155 GDSC1; GDSC2; CTRP2; CCLE 4.8004 6.6323 4.7144 15.5772
IST-SL1 GDSC1; GDSC2 4.8186 6.4429 2.7623 0.9199
SW900 CCLE 4.8243 7.0024 2.2372 1.2545
NCI-H1573 GDSC1; GDSC2; CTRP1; CCLE 4.838 5.6268 4.6453 3.4693
NCI-H1048 GDSC1; GDSC2; CTRP1; CCLE 4.8571 5.8258 4.5742 3.7255
NCI-H2135 GDSC1; GDSC2 4.8608 6.7855 2.6423 1.3995
NCI-H2171 GDSC2 4.8751 7.2031 2.4718 2.2082
NCI-H1688 GDSC1; GDSC2 4.8867 8.182 2.039 4.3945
NCI-H292 GDSC1; GDSC2; CTRP2 4.887 8.4167 4.273 17.8197
IA-LM GDSC1; GDSC2; CCLE 4.9106 6.7904 2.6646 1.0374
NCI-H82 GDSC1; GDSC2; CTRP1 4.9132 5.7688 4.6562 3.6598
COR-L88 GDSC1; GDSC2; CTRP2; CTRP1 4.9288 7.1174 4.7483 15.9361
NCI-H1836 GDSC1; GDSC2; CTRP1 4.9553 5.6743 4.9547 16.2748
NCI-H1666 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.9695 9.8441 3.7633 18.5136
NCI-H1105 GDSC1; GDSC2; CTRP2; CTRP1 4.9766 6.4974 4.9251 15.1647
HCC44 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.9769 6.4218 4.9354 14.3202
NCI-H322M GDSC1; GDSC2 5.0022 8.6222 1.9068 4.9208
NCI-H64 GDSC1; GDSC2 5.015 6.0634 2.9844 0.1316
NCI-H1792 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.0173 6.4401 4.9761 14.0645
NCI-H647 GDSC1; GDSC2; CCLE 5.0319 7.4129 2.4644 1.699
DMS 53 GDSC1; GDSC2; CTRP2 5.0378 6.8898 4.921 14.9851
LUDLU-1 CTRP2; CCLE 5.0469 8.4469 4.4316 15.8745
VMRC-LCD CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.047 6.5462 4.9934 13.9177
SBC-1 GDSC1; GDSC2 5.0471 8.057 2.1906 3.4321
LK-2 GDSC1; GDSC2 5.0498 6.6454 2.7857 0.6251
NCI-H1395 CTRP2 5.0696 10.2466 3.6849 19.5802
NCI-H1694 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.0917 6.535 5.0428 13.6208
SHP-77 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.0921 6.9973 4.9559 13.9074
NCI-H1184 CTRP2; CCLE 5.1196 9.7259 3.969 17.3855
HCC33 GDSC2; CTRP1 5.1486 6.2262 4.6495 3.1328
NCI-H510A GDSC1; GDSC2 5.1609 8.1145 2.2291 3.0577
Calu-6 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.1612 6.3322 5.1396 13.0948
NCI-H460 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.1631 7.4523 4.9097 13.8612
COR-L51 CTRP2; CTRP1 5.1681 6.8657 5.0676 14.0611
NCI-H1693 GDSC1; GDSC2; CTRP2; CCLE 5.1887 6.8455 5.0941 13.1603
NCI-H1975 GDSC1; GDSC2; CTRP1; CCLE 5.1913 6.8316 4.3832 3.8014
NCI-H211 GDSC1; GDSC2; CTRP2; CCLE 5.1998 6.719 5.1299 13.0087
NCI-H23 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.2095 7.1077 5.0569 13.224
EBC-1 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.2112 7.3159 5.0026 13.4041
HARA [Human squamous cell lung carcinoma] CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.2239 7.2083 5.0463 13.2182
NCI-H1993 GDSC1; GDSC2 5.2315 6.7152 2.8342 0.3772
NCI-H250 GDSC2 5.2503 6.844 2.7942 0.4927
COLO 699 CTRP2; CTRP1; CCLE 5.2632 6.7698 5.1893 12.6226
ChaGo-K-1 GDSC1; GDSC2; CTRP2; CTRP1 5.2853 8.2285 4.7704 14.8124
COR-L303 GDSC2 5.2896 6.6893 2.866 0.2848
GLC-82 CCLE 5.2995 8.6482 1.7837 2.614
NCI-H1734 GDSC2; CTRP2 5.3372 7.1266 5.1915 13.0965
NCI-H209 GDSC1; GDSC2 5.338 7.4201 2.6103 1.0368
LB647-SCLC GDSC1; GDSC2 5.3389 7.1647 2.71 0.7055
DMS 454 CTRP2 5.3447 7.6607 5.0403 13.6261
Lu-139 GDSC1; GDSC2 5.356 7.0937 2.7441 0.5841
NCI-H522 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.3755 7.8554 5.0062 12.9341
NCI-H3122 GDSC1; GDSC2 5.3771 7.2111 2.7085 0.6638
NCI-H2196 GDSC2; CTRP2 5.3918 7.2346 5.2224 12.8189
NCI-H1092 GDSC1; GDSC2; CTRP2; CCLE 5.3944 7.3617 5.189 12.2412
NCI-H146 GDSC1; GDSC2 5.4082 8.2117 2.3189 2.279
NCI-H1581 GDSC1; GDSC2; CTRP2; CCLE 5.4118 6.9584 5.3126 11.7709
NCI-H1703 GDSC1; GDSC2; CTRP2; CCLE 5.4124 8.7881 4.6777 14.031
T3M-10 CTRP2; CTRP1; CCLE 5.4156 7.8952 5.035 12.723
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 5.4264 6.8863 5.3436 12.2802
DMS 79 GDSC1; GDSC2 5.4628 7.3354 2.6973 0.667
NCI-H727 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.4855 7.24 5.3232 11.5202
HCC2108 CTRP2; CTRP1 5.4914 7.2543 5.3257 12.1438
COR-L105 GDSC1; GDSC2; CTRP2; CCLE 5.5091 10.6042 3.9573 16.4932
COR-L32 GDSC2 5.5203 7.4356 2.6834 0.6545
NCI-H1436 GDSC1; GDSC2 5.5224 7.1449 2.7916 0.3672
NCI-H2818 GDSC1; GDSC2 5.5525 13.6263 -0.1105 14.3734
NCI-H2141 GDSC1; GDSC2; CTRP2; CTRP1 5.5548 7.3878 5.3561 11.8425
NCI-H2126 CTRP2; CTRP1 5.5943 7.7823 5.2682 12.0525
NCI-H358 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.5959 7.9742 5.1993 11.6507
NCI-H2286 CTRP2; CTRP1; CCLE 5.5995 7.2407 5.4474 10.7685
KNS-62 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.6023 7.4491 5.389 11.5804
COR-L311 GDSC2 5.6027 7.3666 2.7424 0.4426
COR-L321 GDSC1; GDSC2 5.6114 7.364 2.7467 0.4413
SK-MES-1 GDSC1; GDSC2; CTRP2; CCLE 5.6351 7.8991 5.2696 11.2936
HCC15 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.6575 7.0019 5.5702 10.1844
Lu-165 GDSC1; GDSC2 5.6716 6.9282 2.9208 0.0906
COR-L95 GDSC1; GDSC2; CTRP2 5.6907 7.041 5.5975 10.559
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 5.6933 7.3793 5.5097 10.8674
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 5.7074 7.6125 5.4499 11.0464
HCC1833 CTRP2; CTRP1 5.7108 8.2146 5.2278 11.8801
NCI-H1373 CTRP2; CTRP1; CCLE 5.7163 7.7366 5.4161 10.5516
DMS 273 GDSC1; GDSC2; CTRP2; CTRP1 5.7296 8.0755 5.3031 11.5386
Lu-134-A GDSC1; GDSC2 5.7368 7.8008 2.6356 0.6946
HCC2935 CTRP2; CTRP1; CCLE 5.7436 7.5196 5.5201 10.1096
NCI-H661 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.746 7.9237 5.3791 10.604
NCI-H2228 GDSC1; GDSC2; CTRP2; CCLE 5.7844 7.4348 5.5917 9.7459
PaCa-3 GDSC1; GDSC2 5.7887 7.7122 2.6893 0.4939
LK2 CTRP2 5.8003 6.8479 5.7549 9.6622
HCC366 GDSC1; GDSC2; CTRP2 5.8024 7.8855 5.4539 10.7596
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 5.8026 7.5127 5.5864 10.2618
EKVX GDSC1; GDSC2; CTRP2 5.8077 8.1586 5.3527 11.1326
PC-14 GDSC1; GDSC2; CTRP2; CCLE 5.8106 7.0002 5.737 9.1746
SW1271 GDSC1; GDSC2; CTRP2; CCLE 5.824 7.2083 5.7013 9.2558
HCC78 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.8241 7.7673 5.5212 9.8852
SK-LU-1 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.8335 7.4019 5.6555 9.3864
NCI-H1838 GDSC1; GDSC2; CTRP2 5.8429 7.0877 5.7523 9.5378
NCI-H2444 GDSC1; GDSC2; CTRP2; CCLE 5.8451 6.7924 5.8116 8.8251
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 5.8498 7.613 5.6038 10.0595
RERF-LC-A1 CTRP2; CCLE 5.854 8.1618 5.4003 10.2437
NCI-H69 GDSC1; GDSC2 5.8563 7.8348 2.6712 0.5095
NCI-H740 GDSC2 5.859 8.7076 2.3348 1.7185
NCI-H1781 GDSC1; GDSC2; CTRP1 5.8629 7.2949 5.7157 10.0484
NCI-H2087 GDSC1; GDSC2; CTRP2; CCLE 5.8643 9.3447 4.894 12.1128
NCI-H1755 GDSC1; GDSC2; CTRP1 5.8652 7.0173 5.7901 9.758
NCI-H1770 GDSC1; GDSC2 5.8656 7.0953 2.9311 0.0593
NCI-H2172 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.8858 7.674 5.6213 9.3616
NCI-H2405 GDSC1; GDSC2; CTRP2; CTRP1 5.89 8.1072 5.4604 10.4912
NCI-H1876 GDSC1; GDSC2; CTRP1 5.8935 7.8605 5.5548 10.5912
NCI-H1915 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.8937 7.4369 5.7101 9.0276
NCI-H2023 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.9279 7.1141 5.8387 8.4885
HCC4006 CTRP2; CTRP1; CCLE 5.9456 7.544 5.7312 8.8096
LCLC-97TM1 GDSC1; GDSC2; CTRP1 5.9544 7.9678 4.3908 2.7628
NCI-H2595 GDSC1; GDSC2 5.9832 9.5257 2.0567 2.7466
LC-1/sq GDSC1; GDSC2 5.9969 12.4759 0.7359 9.3684
NCI-H2591 GDSC1; GDSC2 6.0182 12.1889 0.8834 8.5829
NCI-H2227 GDSC1; GDSC2 6.0271 7.5761 2.8257 0.1508
HCC95 CTRP2 6.0439 7.0485 5.9801 8.1064
LC-1/sq-SF CTRP2; CTRP1; CCLE 6.0536 8.2567 5.5703 9.1082
Hs 229.T CCLE 6.0757 8.3883 2.2425 0.4737
HOP-62 GDSC1; GDSC2; CTRP2 6.0834 7.5342 5.8839 8.3375
HCC1359 CTRP1 6.0869 6.8247 6.0639 16.2033
HOP-92 GDSC1; GDSC2; CTRP2 6.0911 9.2347 5.1706 11.1195
NCI-H748 GDSC2 6.1045 8.2766 2.6075 0.5773
HCC2279 CTRP2 6.1108 7.7839 5.8223 8.4917
NCI-H2170 GDSC1; GDSC2; CTRP2; CCLE 6.1193 7.2077 6.0237 7.3059
NCI-H2009 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.1261 8.3743 5.5948 8.8359
MOR/CPR CTRP2; CCLE 6.1929 6.9647 6.1579 6.6395
NCI-H3255 GDSC1; GDSC2; CTRP1; CCLE 6.2034 7.3979 6.0549 6.8464
NCI-H1651 GDSC1; GDSC2; CTRP2; CCLE 6.2156 7.6481 5.9858 7.1708
NCI-H513 GDSC1; GDSC2 6.2285 8.047 2.736 0.2365
SBC-5 GDSC1; GDSC2; CTRP2; CCLE 6.2354 6.9403 6.2076 6.3483
NCI-H2804 GDSC1; GDSC2 6.3195 18.3808 -1.8792 20.2073
NCI-H2291 GDSC1; GDSC2; CTRP2 6.3225 8.3131 5.8231 7.9206
NCI-H526 GDSC1; GDSC2; CTRP2 6.3246 7.3802 6.1969 6.4714
RERF-LC-MS GDSC1; GDSC2; CTRP2; CCLE 6.3287 7.9954 5.9672 6.9443
CAL-12T CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3358 7.5576 6.1481 6.267
NCI-H889 CTRP2 6.3482 8.5474 5.7436 8.1726
NCI-H650 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3786 7.3633 6.261 5.7513
NCI-H2347 GDSC1; GDSC2 6.3805 8.3423 2.6886 0.2779
NCI-H2030 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3815 7.0384 6.3483 5.4458
EMC-BAC-1 GDSC1; GDSC2 6.4087 13.5188 0.5089 10.012
DMS 114 GDSC1; GDSC2; CTRP2; CCLE 6.4183 7.6002 6.221 5.7846
RERF-LC-KJ GDSC1; GDSC2; CTRP1 6.4245 9.2731 4.079 3.5193
HCC1195 CTRP2; CTRP1 6.4277 7.3016 6.3336 5.6636
Calu-3 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.4334 8.1378 6.0139 6.5091
COR-L23 GDSC1; GDSC2; CTRP1; CCLE 6.4531 7.144 6.4009 4.9423
Lu-65 GDSC1; GDSC2; CTRP2; CTRP1 6.4603 9.5625 5.3727 9.4144
NCI-H446 GDSC1; GDSC2; CTRP2 6.4607 7.5136 6.2986 5.6974
HCC827 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.4656 7.1628 6.4129 4.9813
NCI-H1623 GDSC1; GDSC2; CTRP2 6.4803 7.7154 6.2419 5.8588
HCC1438 CTRP2 6.4907 7.1245 6.4492 5.0555
HCC1171 CTRP2 6.4931 11.6959 4.356 13.524
NCI-H1650 GDSC1; GDSC2; CTRP2; CCLE 6.5018 8.7388 5.8067 7.1367
LCLC-103H CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.5133 7.7204 6.2747 5.3404
NCI-H1869 GDSC1; GDSC2; CTRP2; CCLE 6.526 7.641 6.32 5.1421
NCI-H1793 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.5336 10.2061 5.1274 9.7139
BEN GDSC1; GDSC2; CTRP2; CTRP1 6.5346 7.0861 6.5048 4.7225
Calu-1 CTRP2; CCLE 6.5815 14.8348 2.8738 18.1226
NCI-H196 GDSC1; GDSC2; CTRP2 6.5847 7.2066 6.5318 4.4711
NCI-H520 GDSC1; GDSC2; CTRP2; CCLE 6.592 7.7082 6.3625 4.816
NCI-H441 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.5958 10.0773 5.2479 9.1106
NCI-H838 GDSC1; GDSC2; CTRP2 6.6026 7.1409 6.5673 4.2897
NCI-H1339 CTRP2; CCLE 6.6199 7.1302 6.5884 3.939
Sq-1 CTRP1; CCLE 6.6396 7.1624 6.5997 3.7256
RERF-LC-Ad2 CTRP2 6.6691 7.433 6.5522 4.1467
NCI-H1355 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.6968 8.2328 6.2355 5.0404
NCI-H2085 GDSC1; GDSC2; CTRP2; CCLE 6.6976 10.1682 5.296 8.7103
NCI-H1563 GDSC1; GDSC2; CTRP2; CCLE 6.7036 13.1134 3.8382 14.3729
NCI-H322 CTRP2; CCLE 6.7047 7.3646 6.6147 3.6066
LOU-NH91 GDSC1; GDSC2; CTRP2; CCLE 6.7588 7.2626 6.7063 3.1358
EPLC-272H GDSC1; GDSC2; CTRP2; CTRP1 6.8088 8.2394 6.3417 4.6229
RERF-LC-Sq1 GDSC1; GDSC2 6.8168 13.033 0.9769 6.809
NCI-H1299 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.8268 10.5731 5.2109 8.7853
ABC-1 GDSC1; GDSC2 6.8619 17.7235 -1.1851 16.6088
RERF-LC-Ad1 CTRP2 7.2475 8.3692 6.6741 2.2937
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 7.757 12.8696 4.8356 9.0571
Hs 888.Lu CTRP2 6.4699 10.5653 4.8925 11.3737
⏷ Show the Full List of 228 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 4.2582 6.4456 2.4543 3.1897
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.304 6.8312 1.9574 33.8787
COV434 CTRP2; CTRP1 2.3005 6.5676 2.0154 33.7138
A2780 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 2.3459 5.6407 2.2346 31.1142
OVK18 GDSC1; GDSC2; CTRP2; CTRP1 2.7519 7.7977 2.1766 31.6773
HEY A8 CTRP2; CTRP1; CCLE 3.279 6.7032 3.0496 25.6286
OVKATE GDSC1; GDSC2; CTRP1 3.939 4.5055 3.939 23.0731
OVCAR-3 GDSC1; GDSC2; CCLE 4.3905 6.319 2.5925 1.9015
RMUG-S CTRP1 4.3985 6.7117 4.2619 40.8846
ES-2 GDSC1; GDSC2; CCLE 4.5516 5.8671 2.8697 0.6037
IGROV-1 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.7222 8.4838 4.0714 18.0313
OVTOKO GDSC1; GDSC2; CTRP2; CCLE 4.8666 9.8415 3.6591 19.1507
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 4.901 9.2176 3.9635 18.9613
TOV-21G GDSC1; GDSC2; CTRP2; CCLE 5.0182 9.6898 3.8812 17.9604
SNU-119 CTRP2 5.2121 8.5768 4.555 15.8401
OAW42 GDSC1; GDSC2; CTRP2; CTRP1 5.3253 7.3084 5.1292 13.3575
SNU-840 CTRP2; CTRP1 5.3314 8.9784 4.5127 15.6816
OV-90 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.336 6.7354 5.2739 12.1252
OVCAR-4 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.3855 7.9132 4.996 12.9433
OC 315 CCLE 5.4497 7.0324 2.4888 0.2029
OVCAR-8 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.4594 7.0368 5.3467 11.5165
COV644 CTRP2; CTRP1 5.7241 7.1388 5.6104 10.4102
OAW28 GDSC1; GDSC2; CTRP2 5.7543 8.068 5.3322 11.3584
FU-OV-1 GDSC1; GDSC2; CTRP2; CCLE 5.76 8.5657 5.1337 11.4663
COV504 CCLE 5.7889 8.5633 2.0573 1.13
OVCAR-5 GDSC1; GDSC2; CTRP2 5.9081 6.8587 5.869 8.9234
COV318 CTRP1; CCLE 5.93 7.4061 4.6377 1.4268
ONCO-DG-1 CTRP2; CCLE 5.9652 7.4346 5.7885 8.5542
JHOC-5 CTRP2; CTRP1 6.021 9.2387 5.0991 11.581
OV7 CTRP2; CTRP1 6.059 7.1883 5.963 8.1205
OC 314 GDSC1; GDSC2; CTRP2; CCLE 6.1417 7.1567 6.0613 7.1133
COV362 CTRP2; CTRP1 6.2227 8.7323 5.5332 9.3323
Caov-4 GDSC1; GDSC2 6.2309 8.2443 2.6678 0.3649
OC 316 CCLE 6.2598 7.8075 2.5083 0.0588
Caov-3 GDSC2; CTRP2; CTRP1 6.2798 7.1394 6.2162 6.5366
TYK-nu CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3028 7.375 6.1749 6.2632
EFO-21 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.3168 8.6498 5.6652 8.1085
Kuramochi GDSC1; GDSC2; CTRP2; CCLE 6.3987 8.2671 5.9211 6.9427
OVSAHO CTRP2; CCLE 6.4028 10.6661 4.7811 11.3449
JHOM-1 CTRP2; CTRP1 6.4096 7.187 6.3458 5.6744
EFO-27 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.5021 8.0162 6.1378 5.8761
OV56 GDSC1; GDSC2; CTRP2 6.5064 7.0668 6.4781 4.905
JHOS-2 GDSC1; GDSC2; CTRP2; CCLE 6.5138 12.8848 3.7849 14.9551
OVISE GDSC1; GDSC2; CTRP2 6.5718 10.7061 4.9163 11.051
TOV-112D GDSC1; GDSC2; CTRP2; CCLE 6.5776 9.4929 5.5169 8.0945
SNU-8 CTRP2 6.5955 7.0791 6.572 4.2956
ES2 CTRP2 6.7202 8.157 6.2941 5.0304
DOV13 GDSC1; GDSC2; CTRP2; CCLE 6.7857 8.1847 6.3452 4.4146
SK-OV-3 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.7876 7.9569 6.4536 3.9942
MCAS CTRP2; CCLE 6.9792 9.0183 6.1184 4.8918
JHOS-4 GDSC1; GDSC2; CTRP1; CCLE 7.0997 9.4847 4.3659 1.2653
OVMANA CTRP1; CCLE 7.6274 13.4283 2.8979 6.3745
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 3.1825 6.3779 3.0128 27.5071
H-STS CTRP2 3.211 4.1355 3.2109 26.7417
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.5794 7.2975 4.3184 18.5476
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 6.4355 7.5736 6.2494 5.9546
Yamato-SS CTRP2 6.6271 7.1841 6.5838 4.1551
Rh18 GDSC1; CTRP2 1.6548 3.8583 1.6471 37.1242
TE 441.T GDSC2; CTRP2 1.8049 4.3777 1.7823 36.1733
G-401 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 1.8712 5.1814 1.7876 34.0121
KYM-1 GDSC1; GDSC2; CTRP2; CCLE 1.8843 4.7989 1.8379 33.8156
Hs 633.T GDSC1; GDSC2 2.104 6.1765 0.7855 19.23
G-402 GDSC1; GDSC2; CTRP2; CCLE 2.399 5.9357 2.2463 30.9104
STS-0421 GDSC1; GDSC2 2.4907 6.8419 0.8289 18.1832
SW982 GDSC1; GDSC2; CTRP2 2.6318 8.3745 1.8581 33.0422
VA-ES-BJ GDSC1; GDSC2 2.8705 6.5937 1.2962 13.7077
TE 617.T CTRP2; CCLE 2.9363 7.4175 2.4914 28.4776
MES-SA GDSC1; GDSC2; CTRP2; CCLE 2.9798 4.6748 2.9736 26.7889
Tm87-16 CTRP2 3.0662 6.8308 2.7882 28.6475
MFH-ino GDSC1; GDSC2 3.1944 7.584 1.0837 13.9712
A-204 GDSC1; GDSC2; CTRP2; CCLE 3.3462 7.336 2.9619 25.7202
BT-16 CTRP2 3.8102 5.7645 3.7729 22.8791
HT-1080 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 3.8532 6.7539 3.6629 21.8873
TTC-709 CTRP2 3.975 9.3763 2.9259 25.3818
EW-8 GDSC1; GDSC2 4.0111 5.5582 2.7126 2.1838
Rh41 GDSC1; GDSC2; CTRP2 4.5362 6.617 4.4319 18.278
SW684 GDSC1; GDSC2 4.9649 6.0794 2.9605 0.1897
Rh30 GDSC1; GDSC2; CCLE 5.3943 7.5657 2.578 0.9568
SW872 GDSC1; GDSC2 5.5283 7.0035 2.8441 0.2396
GCT GDSC1; GDSC2; CTRP2; CCLE 5.9385 7.8835 5.6001 9.2965
Hs 729.T CTRP2; CCLE 6.0516 8.3589 5.5246 9.2828
BT-12 CTRP2 6.3421 6.9797 6.3159 5.9909
RD GDSC1; GDSC2; CTRP2; CCLE 6.4969 10.1914 5.1007 9.8958
SK-LMS-1 GDSC1; GDSC2; CTRP2; CCLE 6.5094 8.9323 5.7224 7.4447
RKN CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.5129 7.0557 6.487 4.5941
SK-UT-1 GDSC1; GDSC2; CTRP2 6.6962 8.4949 6.1112 5.8323
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP1; CCLE; GDSC1; GDSC2; CTRP2 3.2598 8.012 2.6606 26.9677
JL-1 CTRP2 4.3102 7.0918 4.08 20.2258
IST-Mes2 CCLE 4.4648 10.3463 0.4644 10.3237
NCI-H28 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 4.8363 8.8517 4.0471 17.8183
IST-Mes1 GDSC1; GDSC2; CTRP2; CCLE 4.9454 11.0606 3.1878 20.6499
NCI-H2052 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.6906 9.1699 4.798 12.8925
NCI-H2452 GDSC1; GDSC2; CTRP2; CCLE 5.7885 7.9513 5.414 10.3654
MPP 89 GDSC1; GDSC2; CTRP2; CCLE 6.3047 7.6422 6.0835 6.5817
ACC-MESO-1 CTRP2 6.6737 7.1307 6.6467 3.7874
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2; CTRP2 1.639 5.3878 1.5148 37.5801
22Rv1 GDSC1; GDSC2; CTRP2; CCLE 3.7979 8.2849 3.151 23.7846
NCI-H660 GDSC2 5.2484 6.9352 2.7592 0.6022
VCaP GDSC1; GDSC2; CTRP2 6.0778 7.6342 5.8426 8.5079
PC-3 GDSC1; GDSC2; CCLE 6.2574 8.0943 2.7301 0.2056
PaCa-3 CTRP2; CTRP1 6.2749 7.56 6.0816 7.0451
DU145 GDSC1; GDSC2; CTRP2; CCLE 6.5279 8.038 6.1547 5.7493
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 6.0462 6.7947 6.0256 7.9406
A-253 GDSC1; GDSC2; CTRP2; CCLE 6.4086 7.8239 6.1223 6.1686
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -0.914 3.9791 -1.4957 43.9726
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AZ-521 CCLE 1.3124 3.6201 0.9582 16.1418
OCUM-1 GDSC1; GDSC2; CTRP2; CCLE 2.1059 5.4096 2.0095 32.5762
AGS GDSC1; GDSC2; CTRP2; CTRP1 2.1324 5.9495 1.9567 34.4817
RF-48 GDSC1; GDSC2 2.1412 4.9698 1.385 15.6749
SNU-719 CTRP2 2.4977 6.2393 2.2982 32.1452
SNU-1 GDSC1; GDSC2; CTRP2; CCLE 3.3325 6.4041 3.1701 25.072
NUGC-4 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 3.4333 6.9789 3.1522 24.8306
NCC-StC-K140 CTRP2 3.6298 6.2262 3.5224 24.3194
HGC-27 GDSC1; GDSC2; CTRP2; CCLE 3.7927 5.3449 3.7819 21.6821
SNU-16 GDSC1; GDSC2; CTRP2; CCLE 3.8534 4.3538 3.8534 21.2655
23132/87 GDSC1; GDSC2; CTRP2 4.1075 6.7994 3.9294 21.3882
GSS CTRP2 4.3858 6.1962 4.3351 19.0936
SCH GDSC1; GDSC2 4.7211 5.9789 2.9008 0.4782
HSC-39 GDSC1; GDSC2 4.7715 6.7356 2.6181 1.5667
IM95 GDSC1; GDSC2; CTRP2; CCLE 5.0083 7.5699 4.7045 15.0086
ECC10 GDSC1; GDSC2; CTRP2 5.2673 6.8468 5.179 13.3583
MKN28 GDSC1; GDSC2 5.3492 7.4559 2.6011 1.0622
MKN1 GDSC1; GDSC2; CTRP2 5.3585 6.5506 5.325 13.2968
GCIY GDSC1; GDSC2; CCLE 5.4542 7.3394 2.6922 0.5737
SNU-620 CTRP2 5.4867 6.9887 5.3874 11.9373
Fu97 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.6442 7.8973 5.28 11.232
Hs 746.T GDSC1; GDSC2; CTRP2; CCLE 5.6717 7.5174 5.4427 10.5806
NCI-N87 GDSC1; GDSC2; CTRP2; CCLE 5.7443 8.2556 5.2465 11.0902
RERF-GC-1B GDSC1; GDSC2; CCLE 5.7962 7.9019 2.6221 0.5839
GSU CTRP2 5.8 7.1718 5.6847 9.9115
TMK-1 GDSC1; GDSC2 5.9518 7.7598 2.7349 0.3312
SNU-5 GDSC1; GDSC2; CTRP2 5.9844 7.359 5.8331 8.8161
HuG1-N CTRP2 6.0017 11.5409 3.9808 16.1357
SNU-668 CTRP2 6.1428 6.9507 6.1063 7.3527
SNU-601 CTRP2 6.3515 7.2253 6.2723 6.1157
SH-10-TC CTRP2; CTRP1; CCLE 6.3814 7.5853 6.187 6.0053
SK-GT-2 GDSC1; GDSC2 6.3973 8.9809 2.4647 0.8066
NUGC-3 GDSC1; GDSC2; CTRP2; CCLE 6.398 7.9975 6.0384 6.5053
ECC12 GDSC2; CTRP2 6.407 6.9743 6.3864 5.5398
MKN7 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.416 7.7376 6.165 5.9936
MKN45 GDSC1; GDSC2; CTRP2; CCLE 6.4266 11.6792 4.3042 13.1501
BGC-823 CCLE 6.4389 8.7719 2.2434 0.3507
TGBC11TKB GDSC1; GDSC2 6.5067 8.2613 2.7611 0.1425
KE-39 CTRP2; CCLE 6.524 10.1609 5.1407 9.6818
LMSU CTRP2 6.563 11.789 4.3726 13.3052
MKN74 CTRP2; CTRP1; CCLE 6.7644 10.9851 4.9509 9.9358
KATO III GDSC1; GDSC2; CTRP2 6.7667 7.4245 6.6602 3.4617
SNU-216 CTRP2 6.7674 7.586 6.5971 3.7021
SNG-M CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.2768 8.5553 4.632 14.5459
SNU-1077 CTRP2 5.964 8.391 5.42 10.4495
SNU-685 CTRP2 6.5115 7.2043 6.4526 4.9795
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1; GDSC2 2.2818 5.2344 1.4036 15.0513
K5 GDSC1; GDSC2 3.0367 8.7197 0.3818 18.3318
CAL-62 GDSC1; GDSC2 5.0469 6.4933 2.8421 0.4495
ASH-3 GDSC1; GDSC2 5.0892 6.3355 2.9163 0.2392
KMH-2 GDSC1; GDSC2 5.413 7.151 2.746 0.5453
TT GDSC1; GDSC2; CTRP2 5.9137 10.2842 4.5029 14.2499
HTC-C3 GDSC1; GDSC2 5.9398 7.9447 2.6639 0.4896
8305C GDSC1; GDSC2; CTRP2; CCLE 6.0497 7.0867 5.9779 7.6633
B-CPAP GDSC1; GDSC2; CTRP2; CCLE 6.1601 7.4089 6.0087 7.2417
WRO GDSC1; GDSC2 6.1661 12.7724 0.7044 9.221
SW579 CTRP2; CCLE 6.1862 7.9954 5.818 7.8569
8505C GDSC1; GDSC2; CTRP2; CCLE 6.2773 8.2748 5.7937 7.7183
CGTH-W-1 GDSC1; GDSC2; CTRP2 6.3365 7.1837 6.2669 6.181
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 6.3966 7.3395 6.2881 5.9231
FTC-133 GDSC1; GDSC2; CTRP2 6.4684 7.2601 6.3902 5.3352
FTC-238 CTRP2 6.4702 9.1675 5.5723 8.5716
TT2609-C02 GDSC1; GDSC2; CTRP2; CCLE 6.8509 7.5152 6.7139 2.861
BHT-101 GDSC1; GDSC2; CTRP2 6.8694 7.414 6.7741 2.7396
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-38 GDSC1 3.8171 9.5062 0.4003 16.671
BB49-HNC GDSC1; GDSC2 4.0462 13.428 -1.1409 22.3644
DOK GDSC1; GDSC2 4.2547 7.3722 2.0116 5.7533
PCI-15A GDSC1; GDSC2 4.3085 5.7408 2.802 1.3018
HO-1-u-1 GDSC1; GDSC2 4.4076 6.021 2.7337 1.466
Hs 840.T CCLE 4.4115 8.6023 1.2699 6.3723
KOSC-2 GDSC1; GDSC2 4.5748 6.4261 2.6477 1.7231
SAS GDSC1; GDSC2 4.5928 7.2827 2.2738 3.6069
PCI-06A GDSC1; GDSC2 4.7815 8.0569 2.0321 4.7637
OSC-19 GDSC1; GDSC2 4.8163 7.8823 2.1341 4.1222
BB30-HNC GDSC1; GDSC2 4.8521 7.7689 2.2071 3.6537
Ca9-22 GDSC1; GDSC2 4.9142 8.2291 2.0341 4.3745
BHY GDSC1; GDSC2 4.9236 6.6973 2.7088 1.0434
SKN-3 GDSC1; GDSC2 5.0428 7.6817 2.3541 2.4977
NCI-H3118 GDSC1; GDSC2 5.3246 8.9265 1.9603 4.1077
JHU-011 GDSC1; GDSC2 5.4204 10.0522 1.5033 6.5836
HO-1-N-1 GDSC1; GDSC2 5.4254 7.1198 2.7626 0.4747
SNU-1214 CTRP2 5.4691 8.1274 5.0055 13.4019
PCI-04B GDSC1; GDSC2 5.5073 12.7401 0.2862 12.9055
HSC-2 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.6275 7.298 5.4619 10.6383
YD-10B CTRP2 5.6298 6.8 5.5793 10.8146
PE/CA-PJ34 (clone C12) CTRP2 5.6379 7.1387 5.5164 11.0111
BICR 10 GDSC1; GDSC2 5.6548 8.2277 2.433 1.4552
SCC-25 GDSC1; GDSC2; CTRP2; CCLE 5.6625 8.0308 5.249 11.2946
BICR 78 GDSC1; GDSC2 5.6926 8.0272 2.5299 1.0537
BICR 18 CTRP2 5.7618 8.5684 5.1344 12.1057
UPCI-SCC-090 GDSC1; GDSC2 5.818 7.7111 2.7013 0.4499
OSC-20 GDSC1; GDSC2 5.8193 7.5327 2.7657 0.302
Detroit 562 GDSC1; GDSC2; CTRP2; CCLE 5.9278 8.3312 5.4077 10.0279
PCI-30 GDSC1; GDSC2 6.0062 8.228 2.5861 0.6681
JHU-022 GDSC1; GDSC2 6.0605 9.0322 2.298 1.6295
SCC-15 GDSC1; GDSC2 6.0842 7.776 2.7776 0.2043
SCC-4 GDSC1; GDSC2; CTRP2 6.0979 8.3694 5.5679 9.5147
JHU-029 GDSC1; GDSC2 6.1122 8.703 2.4506 1.0609
SNU-899 CTRP2 6.1235 7.4486 5.9561 7.9525
HSC-3 GDSC1; GDSC2; CTRP2 6.1347 11.044 4.3472 14.3609
CAL-33 GDSC1; GDSC2; CTRP2 6.2415 8.8144 5.5144 9.3606
SNU-46 CTRP2 6.2459 7.3478 6.1214 6.9818
PE/CA-PJ49 CTRP2 6.2471 7.379 6.113 7.0094
BICR 6 CTRP2 6.2516 6.8196 6.2401 6.5427
BICR 16 CTRP2 6.325 13.9454 3.0904 18.8133
FaDu GDSC1; GDSC2; CTRP2; CCLE 6.3792 7.2391 6.2987 5.6193
SAT [Human HNSCC] GDSC1; GDSC2 6.4275 13.3205 0.6128 9.2124
SCC-9 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.4439 7.1081 6.4019 5.0819
CAL-27 GDSC1; GDSC2; CTRP2; CCLE 6.5136 7.3271 6.4194 4.8218
BICR 22 GDSC1; GDSC2; CTRP2 6.5244 7.1861 6.4713 4.8726
SNU-1076 CTRP2 6.5247 7.0988 6.4916 4.8001
YD-8 CTRP2 6.5371 12.2027 4.1442 14.2859
BICR 31 GDSC2; CTRP2 6.5698 8.2399 6.1061 6.1611
LB771-HNC GDSC1; GDSC2 6.5727 8.7013 2.6337 0.3229
HSC-4 GDSC2; CTRP2 6.635 11.9093 4.377 13.1332
PE/CA-PJ41 (clone D2) CTRP2 6.8051 7.2191 6.769 2.9463
SNU-1066 CTRP2 6.8735 7.7022 6.6561 3.1909
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 6.9184 10.6428 5.2567 8.8983
BICR 56 CTRP2 7.3613 8.3101 6.7942 1.5851
KON GDSC1; GDSC2 7.4199 17.5758 -0.7478 13.8427
SNU-1041 CTRP2 7.8586 12.8552 4.9217 8.5242
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-4 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 3.2118 6.7005 2.9771 26.0685
253J CTRP2 3.4136 5.5852 3.3728 25.5303
U-BLC1 CTRP2 3.5768 5.555 3.5462 24.4095
SW780 GDSC1; GDSC2; CCLE 3.6953 8.0187 1.277 9.8806
HT-1197 GDSC1; GDSC2; CTRP2; CCLE 4.4051 8.4441 3.7471 20.0375
253J-BV CTRP2 5.082 8.7127 4.3626 16.9369
KU-19-19 GDSC1; GDSC2; CTRP2 5.1907 9.201 4.2715 16.9952
BFTC-905 GDSC1; GDSC2 5.3223 6.8662 2.8148 0.3853
5637 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.3437 7.0802 5.2101 12.3151
JMSU-1 CTRP2; CCLE 5.7408 8.2581 5.2419 11.116
UM-UC-3 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 5.8129 7.0375 5.7313 9.1868
TCCSUP GDSC1; GDSC2; CTRP2; CCLE 5.9052 7.1043 5.8163 8.6305
KMBC-2 CTRP2; CTRP1; CCLE 6.0961 8.7689 5.3892 9.6822
BC-3C CTRP2 6.305 7.6513 6.0804 6.9644
SCaBER CTRP2; CCLE 6.3898 7.5345 6.2146 5.884
UM-UC-1 CTRP2 6.438 7.4312 6.3031 5.7456
CAL-29 GDSC1; GDSC2; CTRP2 6.6051 7.2477 6.5429 4.369
647V GDSC1; GDSC2; CTRP2 6.6154 7.249 6.5537 4.2991
J82 GDSC1; GDSC2; CTRP2; CCLE 6.6737 7.3792 6.5761 3.8281
639V GDSC1; GDSC2; CTRP2; CCLE 6.7657 7.1383 6.7449 2.9851
HT-1376 CTRP1; CCLE; GDSC1; GDSC2; CTRP2 6.9261 9.1134 6.0237 5.3729
VM-CUB-1 CTRP2 6.9608 10.1979 5.5154 7.7286
SW1710 GDSC1; GDSC2; CTRP2 7.0437 8.1394 6.6114 2.9734
RT-112 GDSC1; GDSC2; CTRP2; CCLE 7.6923 12.6013 4.9184 8.3628
T24 GDSC1; GDSC2; CTRP2; CCLE 11.0667 20.1387 3.6232 8.4356
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NEC8 GDSC1; GDSC2 0.5833 1.8747 0.5723 26.676
PA-1 GDSC1; GDSC2 1.3927 5.0119 0.5981 22.978
KGN GDSC1; GDSC2 1.5582 5.5947 0.5137 22.7622
NT2-D1 GDSC1; GDSC2 1.7573 4.4444 1.2163 18.1181
HEY GDSC1; GDSC2 2.4237 5.1515 1.5819 13.498
JAR GDSC1; GDSC2 2.5616 5.1659 1.709 12.6562
OVCA433 GDSC1; GDSC2 2.9215 7.063 1.108 15.1085
JEG-3 GDSC1; GDSC2 3.2758 5.5789 2.1548 7.5241
SW954 GDSC1; GDSC2 3.3991 9.7479 0.173 18.83
TC-YIK GDSC1; GDSC2 4.4648 6.1502 2.7083 1.5157
C-33 A GDSC1; GDSC2 4.6242 6.5322 2.6282 1.7007
OV17R GDSC1; GDSC2 4.6874 7.2172 2.3602 3.0789
PWR-1E GDSC1; GDSC2 4.7481 6.9221 2.5255 2.0422
NCC-IT GDSC2 4.8046 6.6527 2.6697 1.2947
OVMIU GDSC1; GDSC2 4.8534 11.2445 0.5531 12.6422
CAL-39 GDSC1; GDSC2 4.8939 7.2607 2.4569 2.1877
SiHa GDSC1; GDSC2 4.908 5.9361 2.9898 0.1508
OVCA420 GDSC1; GDSC2 4.9094 6.7061 2.6985 1.066
C-4-I GDSC1; GDSC2 5.0965 6.6747 2.7943 0.5667
ME-180 GDSC1; GDSC2 5.1041 8.714 1.9266 4.6398
LB831-BLC GDSC1; GDSC2 5.2699 7.1366 2.6912 0.7945
ACC-OV7 GDSC1; GDSC2 5.2986 9.5792 1.647 6.0053
HEC-1 GDSC1; GDSC2 5.3609 7.1919 2.709 0.6726
SKG-IIIa GDSC1; GDSC2 5.5188 6.9995 2.842 0.2468
MS751 GDSC1; GDSC2 5.5365 7.1555 2.7932 0.3462
SW962 GDSC1; GDSC2 5.5636 8.3753 2.3285 2.0533
SW756 GDSC1; GDSC2 5.6379 6.9077 2.9161 0.1012
Ca Ski GDSC1; GDSC2 5.9083 8.4562 2.4574 1.1508
HeLa GDSC1; GDSC2; CTRP2 5.9857 6.4668 5.9842 8.2791
HT-3 GDSC1; GDSC2 6.0799 7.9089 2.7299 0.2894
SKN GDSC1; GDSC2 6.1098 7.9298 2.7336 0.2734
DoTc2 4510 GDSC1; GDSC2 6.176 7.8027 2.801 0.1508
DSH1 GDSC1; GDSC2 6.1946 7.9282 2.7647 0.1986
PEO1 GDSC1; GDSC2 6.2376 8.1389 2.7074 0.2846
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 6.258 7.9181 2.7905 0.154
SiSo GDSC1; GDSC2 6.2809 8.2224 2.6941 0.2965
UWB1.289 GDSC1; GDSC2 6.3994 8.7794 2.54 0.6165
BPH-1 GDSC1; GDSC2 6.8787 9.1792 2.5788 0.335
JHOS-3 GDSC1; GDSC2 6.9057 8.7519 2.7336 0.1176
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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2 Reaching for high-hanging fruit in drug discovery at protein-protein interfaces. Nature. 2007 Dec 13;450(7172):1001-9.