Details of the Drug

General Information of Drug (ID: DM5OKZB)

Drug Name

P-218

Synonyms

BT-1; Dihydrofolate reductase inhibitors (Plasmodium infection); Dihydrofolate reductase inhibitors (Plasmodium infection), MMV

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Investigative	[1]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C18H24N4O4
Canonical SMILES: CCC1=C(C(=NC(=N1)N)N)OCCCOC2=CC=CC=C2CCC(=O)O
InChI: 1S/C18H24N4O4/c1-2-13-16(17(19)22-18(20)21-13)26-11-5-10-25-14-7-4-3-6-12(14)8-9-15(23)24/h3-4,6-7H,2,5,8-11H2,1H3,(H,23,24)(H4,19,20,21,22)
InChIKey: VDGXZSSDCDPCRF-UHFFFAOYSA-N

Cross-matching ID

References

1	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.