Details of the Drug

General Information of Drug (ID: DM5OYWF)

• Drug Name: 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE
• Synonyms: 2',5'-dideoxy-adenosine 3'-monophosphate; 2',5'-Dideoxyadenosine 3'-monophosphate; AC1L9H2O; SCHEMBL1920523; CTK8E3534; 2',5'-dideoxy-3'-adenylic acid; 2,5-Dideoxyadenosine 3-monophosphate; AKOS025394264; DB06843; 121878-11-3; RT-018381; 2',5'-Dideoxyadenosine 3'-phosphoric acid; [(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-yl]oxyphosphonic acid; [(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-yl] dihydrogen phosphate

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 315.22
  Logarithm of the Partition Coefficient (xlogp); -1
  Rotatable Bond Count (rotbonds); 3
  Hydrogen Bond Donor Count (hbonddonor); 3
  Hydrogen Bond Acceptor Count (hbondacc); 9
• Chemical Identifiers:
  Formula: C10H14N5O5P
  IUPAC Name: [(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-yl] dihydrogen phosphate
  Canonical SMILES: C[C@@H]1[C@H](C[C@@H](O1)N2C=NC3=C(N=CN=C32)N)OP(=O)(O)O
  InChI: InChI=1S/C10H14N5O5P/c1-5-6(20-21(16,17)18)2-7(19-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7H,2H2,1H3,(H2,11,12,13)(H2,16,17,18)/t5-,6+,7-/m1/s1
  InChIKey: NFGZMOICZSFFLB-DSYKOEDSSA-N
• Cross-matching ID:
  PubChem CID: 444894
  DrugBank ID: DB06843
  TTD ID: D0K7HT

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Adenylate cyclase type 2 (ADCY2)	TTBQ9IM	ADCY2_HUMAN	Inhibitor	[1]

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.