General Information of Drug (ID: DM5P1KQ)

Drug Name
RN6G
Synonyms PF-04382923; PF-4382923
Indication
Disease Entry ICD 11 Status REF
Age-related macular degeneration 9B75.0 Discontinued in Phase 2 [1]
Cross-matching ID
TTD ID
D0Z1VS

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Amyloid beta A4 protein (APP) TTE4KHA A4_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Age-related macular degeneration
ICD Disease Classification 9B75.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Amyloid beta A4 protein (APP) DTT APP 1.60E-02 -0.07 -0.31
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031573)
2 Advances in the management of macular degeneration. F1000Prime Rep. 2014; 6: 29.