Details of the Drug

General Information of Drug (ID: DM5XUQL)

Drug Name
CPI-613
Synonyms
CPI-613; 95809-78-2; 6,8-bis(benzylthio)octanoic acid; CPI 613; MLS006010202; SCHEMBL1062218; 6,8-Bis(benzylsulfanyl)octanoic acid; Octanoic acid, 6,8-bis((phenylmethyl)thio)-; Octanoic acid, 6,8-bis[(phenylMethyl)thio]-; 6,8-Bis[(phenylmethyl)thio]octanoic acid; CPI613; CHEMBL3186849; QCR-193; AOB1058; MolPort-023-219-128; HMS3656L06; C22H28O2S2; BCP04663; EX-A2043; s2776; AKOS025142095; BCP9000552; DB12109; RL06062; CS-0961; NCGC00344764-01; SMR004701300; AS-16613; BC261916; AK174899; HY-15453; BCP0726000030; KB-293127; AB0035874
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Phase 3 [1]
Pancreatic cancer 2C10 Phase 3 [2]
B-cell lymphoma 2A86 Phase 2 [3]
Myelodysplastic syndrome 2A37 Phase 2 [1]
Recurrent adult burkitt lymphoma 2A85.6 Phase 2 [3]
Metastatic colorectal cancer 2B91 Phase 1 [3]
T-cell lymphoma 2A90 Phase 1 [3]
⏷ Show the Full List of Indication(s)
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 388.6
Logarithm of the Partition Coefficient (xlogp) 5.5
Rotatable Bond Count (rotbonds) 13
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C22H28O2S2
IUPAC Name
6,8-bis(benzylsulfanyl)octanoic acid
Canonical SMILES
C1=CC=C(C=C1)CSCCC(CCCCC(=O)O)SCC2=CC=CC=C2
InChI
InChI=1S/C22H28O2S2/c23-22(24)14-8-7-13-21(26-18-20-11-5-2-6-12-20)15-16-25-17-19-9-3-1-4-10-19/h1-6,9-12,21H,7-8,13-18H2,(H,23,24)
InChIKey
ZYRLHJIMTROTBO-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24770514
CAS Number
95809-78-2
UNII
E76113IR49
DrugBank ID
DB12109
TTD ID
D07NVI
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Alpha-ketoglutarate dehydrogenase (OGDH) TTH8T6I ODO1_HUMAN Modulator [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 6.5543 7.4061 6.5361 18.1866
EW-13 GDSC1 5.7007 7.3578 5.6324 29.173
U2OS GDSC1 5.7417 6.7639 5.7346 28.2733
G-292 clone A141B1 GDSC1 6.0782 7.4208 6.0278 24.3436
EW-22 GDSC1 6.4133 7.6257 6.3543 20.2121
CAL-78 GDSC1 6.4707 7.0647 6.4688 19.1286
EW-24 GDSC1 6.4755 6.902 6.4753 19.0575
SK-ES-1 GDSC1 6.5032 7.1791 6.4985 18.74
MHH-ES-1 GDSC1 6.5177 7.3211 6.5052 18.6071
CAL-72 GDSC1 6.5177 7.0816 6.5162 18.5382
NOS-1 [Human HNSCC] GDSC1 6.5995 7.7437 6.5331 17.9346
HuO9 GDSC1 6.9535 7.9956 6.8592 13.7001
MG-63 GDSC1 7.1168 8.0448 7.0236 11.6547
CADO-ES1 GDSC1 7.2093 8.145 7.0935 10.6563
EW-7 GDSC1 7.3562 8.1466 7.2525 8.7423
ES7 GDSC1 7.3814 8.5615 7.1183 9.5766
A-673 GDSC1 7.3945 14.544 4.2106 28.1638
SK-PN-DW GDSC1 7.4322 8.178 7.3239 7.8281
CHSA8926 GDSC1 7.4757 7.9954 7.4291 6.8593
NY GDSC1 7.5104 8.7343 7.1736 8.5386
EW-16 GDSC1 7.5417 8.2845 7.4012 6.6973
SaOS-2 GDSC1 7.5687 8.2783 7.4322 6.3343
SJSA-1 GDSC1 7.5716 8.3498 7.4059 6.5102
EW-1 GDSC1 7.6376 8.7173 7.3077 6.9314
ES1 GDSC1 7.7058 8.7135 7.3759 6.1025
HuO-3N1 GDSC1 7.9809 9.3031 7.3324 5.3345
EW-18 GDSC1 8.2268 10.9819 6.6935 9.489
HOS GDSC1 8.3196 9.6099 7.4434 3.3591
ES6 GDSC1 8.5854 10.7637 7.0704 5.4612
ES4 GDSC1 8.8088 11.0376 7.0908 4.7139
TC-71 GDSC1 10.0538 11.6262 7.4839 0.4934
ES8 GDSC1 10.2347 11.914 7.45 0.5
EW-3 GDSC1 10.4864 12.3913 7.3748 0.5988
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 152 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 6.7796 7.6892 6.7383 15.5191
VL51 GDSC1 2.5216 5.9632 2.4295 65.4959
CML-T1 GDSC1 3.8425 28.7209 -6.0008 50.3441
SU-DHL-16 GDSC1 5.3737 6.0133 5.3736 32.8294
H9 GDSC1 5.4952 6.683 5.4848 31.3747
Ku812 GDSC1 5.6512 7.1829 5.6048 29.6522
MLMA GDSC1 5.6599 7.2281 5.608 29.5781
CESS GDSC1 5.6638 7.6913 5.5276 30.0597
GA-10 GDSC1 5.8057 7.0123 5.7858 27.554
SUP-HD1 GDSC1 5.8084 7.4352 5.7354 27.8585
Ramos.2G6.4C10 GDSC1 5.9318 6.8694 5.9252 25.8938
SU-DHL-5 GDSC1 5.9391 6.5801 5.9386 25.7642
RC-K8 GDSC1 6.0422 6.9402 6.0355 24.5148
RPMI-8866 GDSC1 6.1768 7.7613 6.07 23.4803
QIMR-WIL GDSC1 6.1996 7.0882 6.1902 22.5641
CTB-1 GDSC1 6.2199 7.177 6.2055 22.3414
SUP-M2 GDSC1 6.2539 7.1692 6.2414 21.9049
NU-DUL-1 GDSC1 6.2752 7.3059 6.252 21.7065
MEG-01 GDSC1 6.2849 7.3103 6.2618 21.5849
SU-DHL-10 GDSC1 6.3095 7.807 6.204 21.8155
BC-1 GDSC1 6.3537 7.7081 6.2738 21.0943
SU-DHL-8 GDSC1 6.3719 7.4365 6.3394 20.5581
Farage GDSC1 6.3914 7.8378 6.2859 20.7927
Sc-1 GDSC1 6.3989 6.9506 6.398 20.0192
DND-41 GDSC1 6.4115 7.212 6.4023 19.914
MV4-11 GDSC1 6.4116 7.2287 6.4013 19.92
ATN-1 GDSC1 6.4142 8.7252 6.0286 22.4224
ALL-PO GDSC1 6.416 7.8184 6.3173 20.4402
HAL-01 GDSC1 6.4188 7.5147 6.3786 20.0217
MOLP-8 GDSC1 6.4208 7.6304 6.3615 20.1206
P12-Ichikawa GDSC1 6.4583 6.8979 6.4581 19.2724
P31/FUJ GDSC1 6.4702 7.1039 6.4673 19.1409
KM-H2 GDSC1 6.4729 7.4781 6.4415 19.2889
EB2 GDSC1 6.4866 7.1615 6.4822 18.9454
SIG-M5 GDSC1 6.509 6.8376 6.509 18.6378
LP-1 GDSC1 6.5095 7.1056 6.5072 18.6457
MY-M12 GDSC1 6.5138 7.1917 6.5089 18.6081
U-698-M GDSC1 6.5354 7.2057 6.5304 18.3391
AMO1 GDSC1 6.5414 7.0028 6.541 18.235
OCI-AML-2 GDSC1 6.5415 6.9998 6.5411 18.2341
NK-92MI GDSC1 6.5469 7.8265 6.458 18.7405
SU-DHL-1 GDSC1 6.5544 6.8895 6.5543 18.0706
SU-DHL-4 GDSC1 6.5566 7.0497 6.5559 18.0474
SUP-T1 GDSC1 6.5646 7.2101 6.5602 17.9698
DEL GDSC1 6.5682 6.9037 6.5682 17.8973
K-562 GDSC1 6.6265 7.4997 6.6022 17.3226
P30/OHK GDSC1 6.6351 7.9573 6.5219 17.802
MOLT-16 GDSC1 6.6548 7.7378 6.5943 17.2046
JSC-1 GDSC1 6.6826 7.6119 6.6466 16.6975
HC-1 GDSC1 6.6933 7.4309 6.6799 16.418
KMOE-2 GDSC1 6.7013 7.8661 6.6169 16.7819
KE-37 GDSC1 6.7148 7.5484 6.69 16.2221
DG-75 GDSC1 6.723 7.8014 6.6552 16.4011
LC4-1 GDSC1 6.7411 7.7067 6.6936 16.0412
KOPN-8 GDSC1 6.7681 7.9777 6.6616 16.0968
Karpas-231 GDSC1 6.8161 8.0184 6.7029 15.5431
GR-ST GDSC1 6.8225 8.0797 6.6923 15.5787
RS4;11 GDSC1 6.8226 9.9196 5.9423 20.9261
THP-1 GDSC1 6.8427 8.3824 6.6153 16.0018
YT GDSC1 6.8506 16.2302 2.8917 34.8827
LAMA-84 GDSC1 6.8778 7.8247 6.8184 14.4114
NKM-1 GDSC1 6.8817 8.546 6.5966 15.9265
Karpas-45 GDSC1 6.883 7.7114 6.8459 14.1997
HL-60 GDSC1 6.9067 7.6885 6.8752 13.8675
MOLT-13 GDSC1 6.9201 9.0643 6.4247 16.974
L-540 GDSC1 6.9211 8.0058 6.821 14.1434
BV-173 GDSC1 6.9249 7.7995 6.8747 13.7621
NB4 GDSC1 6.9273 7.5701 6.9127 13.5008
CA46 GDSC1 6.9426 10.128 5.9637 20.199
SU-DHL-6 GDSC1 7.01 8.122 6.884 13.2112
KCL-22 GDSC1 7.0108 8.5869 6.7182 14.3786
A3/Kawakami GDSC1 7.0432 7.7087 7.0185 12.1173
BALL-1 GDSC1 7.0635 8.0048 6.9767 12.2765
RCH-ACV GDSC1 7.0645 8.3822 6.8541 13.123
JJN-3 GDSC1 7.1081 8.0418 7.0149 11.7625
GDM-1 GDSC1 7.1114 8.2256 6.9604 12.121
WIL2 NS GDSC1 7.1201 7.958 7.0509 11.4507
HT GDSC1 7.127 7.7738 7.0981 11.0974
MOLM-13 GDSC1 7.1374 8.3766 6.9343 12.1657
Karpas-620 GDSC1 7.1403 8.3365 6.9523 12.0223
MC116 GDSC1 7.1588 7.7114 7.1416 10.6245
Jurkat GDSC1 7.1603 8.382 6.9569 11.8833
Reh GDSC1 7.1861 7.8217 7.1533 10.3849
MHH-PREB-1 GDSC1 7.2012 7.996 7.1294 10.4563
MOLT-4 GDSC1 7.2048 12.3531 5.1298 24.3685
697 GDSC1 7.2061 13.3862 4.6197 27.0676
VAL GDSC1 7.2115 8.5191 6.9578 11.6094
MN-60 GDSC1 7.2234 8.0705 7.1322 10.3112
NALM-6 GDSC1 7.2399 7.9779 7.1764 9.9175
RPMI-8402 GDSC1 7.2402 7.9917 7.173 9.9381
L-1236 GDSC1 7.242 12.7178 4.9831 25.0298
ALL-SIL GDSC1 7.2442 8.2486 7.0961 10.4479
Karpas-422 GDSC1 7.2817 7.8551 7.2503 9.1809
SUP-B15 GDSC1 7.2882 11.9378 5.4105 22.3239
PF-382 GDSC1 7.2883 8.3208 7.117 10.0636
EoL-1 GDSC1 7.2953 7.9364 7.2473 9.121
OCI-Ly19 GDSC1 7.2984 8.2483 7.1545 9.7437
RPMI-8226 GDSC1 7.3061 8.0145 7.2388 9.1163
BE-13 GDSC1 7.3077 8.0797 7.2213 9.2271
Hs 445 GDSC1 7.3116 14.6875 4.0665 29.1062
KMS-12-BM GDSC1 7.3126 8.2363 7.1742 9.5289
L-363 GDSC1 7.3335 7.8383 7.3095 8.4849
IM-9 GDSC1 7.3476 7.9509 7.3008 8.4597
DoHH2 GDSC1 7.3579 8.0679 7.2796 8.5451
TK [Human B-cell lymphoma] GDSC1 7.3601 8.123 7.2646 8.6365
Raji GDSC1 7.3701 7.9285 7.3307 8.129
OCI-AML-3 GDSC1 7.3981 7.895 7.3686 7.714
NOMO-1 GDSC1 7.4037 7.9042 7.3726 7.6548
DB GDSC1 7.4093 8.2931 7.2569 8.4261
WSU-DLCL2 GDSC1 7.4318 7.9223 7.3993 7.3132
SR GDSC1 7.453 8.0705 7.3824 7.3061
OPM-2 GDSC1 7.4583 8.0762 7.3864 7.2497
PL-21 GDSC1 7.4696 8.3863 7.2839 7.9188
JURL-MK1 GDSC1 7.4935 8.3233 7.3346 7.4281
SKM-1 GDSC1 7.4965 7.9142 7.4713 6.4564
L-428 GDSC1 7.4974 8.5978 7.222 8.2374
BL-41 GDSC1 7.5167 7.9281 7.4902 6.2127
Jiyoye GDSC1 7.521 8.7635 7.1709 8.509
JVM-2 GDSC1 7.5214 9.3464 6.8957 10.6114
Loucy GDSC1 7.5326 8.1793 7.4318 6.5262
CTV-1 GDSC1 7.5388 8.2595 7.408 6.6634
HEL GDSC1 7.5505 8.0307 7.5007 5.9474
HDLM-2 GDSC1 7.5807 8.4944 7.3528 6.8587
SK-MM-2 GDSC1 7.6016 8.3642 7.4311 6.1751
P32/ISH GDSC1 7.6186 8.2288 7.5048 5.5512
Mono-Mac-6 GDSC1 7.6458 12.6507 5.3733 21.0598
HH [Human lymphoma] GDSC1 7.6612 10.1629 6.6247 12.1223
SCC-3 GDSC1 7.6846 8.3483 7.5237 5.0806
CCRF-CEM GDSC1 7.8 14.5695 4.5471 25.0178
WSU-NHL GDSC1 7.8677 8.7288 7.5202 4.292
EJM GDSC1 7.9683 11.3568 6.2951 13.4514
KY821 GDSC1 7.9731 8.9401 7.5073 3.9841
ME1 GDSC1 8.0499 9.0057 7.5381 3.466
Daudi GDSC1 8.0553 10.8579 6.6169 10.6807
EHEB GDSC1 8.1966 9.9977 7.1599 5.9466
ARH-77 GDSC1 8.2363 9.7547 7.3109 4.6365
KMS-11 GDSC1 8.3931 11.3807 6.625 9.4656
ML-2 GDSC1 8.4005 11.8483 6.3986 11.1596
RPMI-6666 GDSC1 8.5633 10.5007 7.1823 4.6715
ST486 GDSC1 8.5856 10.1642 7.3584 3.291
U266B1 GDSC1 8.7973 10.194 7.4746 1.9941
ROS-50 GDSC1 8.8463 14.5225 5.4144 16.4899
Granta-519 GDSC1 8.8478 12.0994 6.6067 8.2253
Karpas-299 GDSC1 8.8871 10.5589 7.3624 2.5798
JVM-3 GDSC1 9.1853 11.1481 7.2695 2.6273
OCI-AML-5 GDSC1 9.29 10.1441 7.7236 0.1729
TUR GDSC1 9.4527 17.1888 4.5529 19.4513
BC-3 GDSC1 9.4784 14.7685 5.7546 12.4356
EM-2 GDSC1 9.5545 11.7729 7.1973 2.4512
RL GDSC1 9.6382 11.1412 7.4954 0.7461
OCI-M1 GDSC1 9.784 10.9515 7.6225 0.2274
KG-1 GDSC1 10.0501 12.3008 7.223 1.6225
⏷ Show the Full List of 152 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-12 GDSC1 5.53 6.8473 5.5108 30.9952
KYSE-50 GDSC1 6.389 7.4338 6.3579 20.335
SK-GT-4 GDSC1 6.4948 7.2672 6.4852 18.8756
KYSE-220 GDSC1 6.5332 7.3792 6.5165 18.4399
OACM5.1 C GDSC1 6.585 7.6245 6.5396 17.978
OACP4 C GDSC1 6.8539 7.8234 6.7927 14.722
FLO-1 GDSC1 7.0887 8.2624 6.9232 12.505
KYAE-1 GDSC1 7.313 7.9571 7.2616 8.9229
ESO-26 GDSC1 7.6579 8.366 7.4884 5.4733
HCE-4 GDSC1 10.651 12.3035 7.4677 0.2729
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 6.3778 7.7183 6.2978 20.7938
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC1 4.7464 6.7447 4.697 40.9215
SiMa GDSC1 5.2456 7.5562 5.1025 35.2656
SJNB-6 GDSC1 5.4257 6.8283 5.4035 32.3172
GI-ME-N GDSC1 5.4321 6.9058 5.4035 32.2769
NB1 GDSC1 5.482 7.0089 5.4458 31.7011
SJNB-13 GDSC1 5.5089 6.6598 5.5 31.1947
NH-12 GDSC1 5.5114 6.4516 5.5088 31.1236
NB(TU)1 GDSC1 5.5167 7.4276 5.422 31.6301
KP-N-YS GDSC1 5.6972 7.442 5.6142 29.3097
TGW GDSC1 5.9749 7.3377 5.9293 25.6033
SK-N-MC-IXC GDSC1 6.0068 7.1008 5.9889 25.0278
SJNB-5 GDSC1 6.0306 7.3722 5.9839 24.9146
SK-N-FI GDSC1 6.149 7.6028 6.0729 23.6261
Kelly GDSC1 6.3261 7.4742 6.2853 21.1836
SJNB-17 GDSC1 6.4446 7.9133 6.3255 20.2194
IMR-5 GDSC1 6.4513 7.3123 6.4365 19.4523
SJNB-14 GDSC1 6.4576 7.0012 6.4566 19.2863
LA-N-6 GDSC1 6.4952 7.2208 6.4883 18.8536
MHH-NB-11 GDSC1 6.5043 7.2519 6.496 18.7479
GOTO GDSC1 6.5276 7.5541 6.4893 18.6492
SK-N-SH GDSC1 6.5808 7.8712 6.4844 18.3673
SJNB-12 GDSC1 6.7954 7.9687 6.6938 15.7232
CHP-212 GDSC1 6.936 10.3272 5.8633 20.9324
SK-N-BE(2)-M17 GDSC1 7.0652 8.3842 6.8541 13.1192
SJNB-7 GDSC1 7.1961 8.2733 7.0353 11.1353
CHP-134 GDSC1 7.2095 7.9158 7.1588 10.2104
KP-N-YN GDSC1 7.3248 8.4816 7.0924 10.0515
SK-N-AS GDSC1 7.4912 7.9502 7.4575 6.5787
SK-N-DZ GDSC1 7.558 8.0118 7.5143 5.8125
SJNB-10 GDSC1 7.6247 8.3815 7.4475 5.9401
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 7.9641 9.0194 7.4601 4.3904
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 578T GDSC1 5.5344 6.3893 5.5331 30.828
HDQ-P1 GDSC1 5.6474 7.2568 5.5906 29.765
MDA-MB-330 GDSC1 5.6531 7.1504 5.6109 29.6025
HCC1599 GDSC1 5.9374 7.1562 5.9111 25.9484
CAL-120 GDSC1 6.0368 6.8784 6.0323 24.5686
HCC1419 GDSC1 6.1186 7.0817 6.1068 23.5918
MDA-MB-436 GDSC1 6.225 7.184 6.2103 22.2798
MRK-nu-1 GDSC1 6.2473 7.0644 6.2407 21.9504
OCUB-M GDSC1 6.2527 7.4289 6.2132 22.0924
COLO 824 GDSC1 6.2544 7.7112 6.1653 22.3948
HCC1395 GDSC1 6.273 7.1481 6.2627 21.6525
MDA-MB-453 GDSC1 6.3691 7.1202 6.3633 20.4228
BT-20 GDSC1 6.3879 7.001 6.3862 20.1622
HCC1187 GDSC1 6.3893 7.0438 6.3866 20.1508
MDA-MB-231 GDSC1 6.396 7.2564 6.3832 20.1308
CAL-51 GDSC1 6.4098 6.9933 6.4084 19.8863
Evsa-T GDSC1 6.443 6.9696 6.4423 19.4669
MCF-7 GDSC1 6.4683 7.1967 6.4619 19.1866
HCC38 GDSC1 6.4782 7.3176 6.4642 19.1105
UACC-812 GDSC1 6.4818 7.5734 6.4371 19.2637
HCC1954 GDSC1 6.5049 7.1473 6.5014 18.7109
DU4475 GDSC1 6.511 7.0531 6.5098 18.6204
HCC1569 GDSC1 6.5137 7.4705 6.486 18.7546
MFM-223 GDSC1 6.5148 6.9576 6.5146 18.5665
MDA-MB-468 GDSC1 6.5162 7.0802 6.5146 18.5573
EFM-19 GDSC1 6.5181 7.3847 6.5001 18.6373
HCC2157 GDSC1 6.5393 9.6125 5.794 23.3678
BT-549 GDSC1 6.5402 7.1731 6.5366 18.2703
BT-474 GDSC1 6.5422 7.0504 6.5413 18.2281
MDA-MB-175-VII GDSC1 6.5536 7.2061 6.549 18.109
HCC1500 GDSC1 6.6498 7.2259 6.6467 16.8968
HCC2218 GDSC1 6.7415 7.7051 6.6944 16.0333
CAMA-1 GDSC1 6.9009 9.9878 5.9884 20.2235
HCC1806 GDSC1 7.0614 7.7534 7.031 11.9271
MDA-MB-157 GDSC1 7.2082 8.2028 7.0731 10.8047
YMB-1-E GDSC1 7.2112 7.9512 7.1519 10.247
HCC1937 GDSC1 7.3694 8.1003 7.282 8.4647
HCC70 GDSC1 7.4289 8.0395 7.3655 7.5577
UACC-893 GDSC1 7.4558 8.7191 7.1254 9.16
ZR-75-30 GDSC1 7.4567 8.0771 7.3844 7.2717
HCC1428 GDSC1 7.4776 7.8507 7.4627 6.6251
EFM-192A GDSC1 7.4906 8.0739 7.4222 6.8223
AU565 GDSC1 7.4944 8.2174 7.3766 7.122
MDA-MB-361 GDSC1 7.505 8.1032 7.4285 6.6992
CAL-148 GDSC1 7.5304 8.0108 7.4846 6.1713
BT-483 GDSC1 7.5335 8.0517 7.4759 6.2136
MDA-MB-415 GDSC1 7.5397 8.0171 7.4929 6.0616
CAL-85-1 GDSC1 7.5633 8.3402 7.4012 6.5865
T-47D GDSC1 7.5701 14.0587 4.6053 25.6318
HCC202 GDSC1 7.5934 9.3358 6.969 9.7333
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC1 6.4405 7.0105 6.4392 19.5019
AM-38 GDSC1 6.4889 7.1072 6.4862 18.9056
GI-1 GDSC1 6.5322 7.4213 6.5113 18.4796
U-87MG ATCC GDSC1 6.569 7.0414 6.5685 17.8906
GB-1 GDSC1 6.6821 7.26 6.6786 16.4958
KNS-42 GDSC1 6.6822 7.1623 6.6811 16.4795
SF268 GDSC1 6.7329 8.0713 6.5971 16.7345
U-251MG GDSC1 6.7867 7.4436 6.7766 15.2301
H4 GDSC1 6.8849 7.6857 6.8523 14.147
LN-18 GDSC1 6.907 7.5169 6.8964 13.7295
LN-405 GDSC1 6.9176 7.6895 6.8867 13.7272
Hs 683 GDSC1 6.9602 7.6542 6.9376 13.1413
8-MG-BA GDSC1 7.1047 8.0379 7.0123 11.8002
D-247MG GDSC1 7.1318 8.3724 6.9299 12.2264
SW1088 GDSC1 7.1583 7.8813 7.1109 10.8285
Becker GDSC1 7.1895 7.7984 7.1612 10.3123
LNZTA3WT4 GDSC1 7.2776 7.974 7.2185 9.4165
PFSK-1 GDSC1 7.361 8.1669 7.2509 8.727
LN-229 GDSC1 7.3644 7.8927 7.3325 8.1509
D-263MG GDSC1 7.3924 7.945 7.351 7.8644
SNB-75 GDSC1 7.3934 8.2697 7.2488 8.5677
KINGS-1 GDSC1 7.4249 8.1513 7.3254 7.8568
KALS-1 GDSC1 7.4305 8.2937 7.2793 8.154
U-118MG GDSC1 7.4386 7.9708 7.395 7.3023
DK-MG GDSC1 7.4577 7.9609 7.4183 7.0357
SF126 GDSC1 7.4733 7.8651 7.4556 6.6968
GaMG GDSC1 7.474 7.9763 7.4322 6.8481
YH-13 GDSC1 7.4767 7.9399 7.4441 6.7524
SF539 GDSC1 7.477 7.9549 7.4409 6.7721
KS-1 [Human Krukenberg tumour] GDSC1 7.4773 9.0106 7.0128 9.9109
MOG-G-UVW GDSC1 7.4923 8.3853 7.3081 7.6266
SK-MG-1 GDSC1 7.499 8.086 7.4275 6.7388
D-566MG GDSC1 7.5059 8.1285 7.421 6.7465
SW1783 GDSC1 7.5065 8.4045 7.315 7.5045
D-542MG GDSC1 7.5217 8.0091 7.4755 6.2827
D-423MG GDSC1 7.5218 8.3693 7.3456 7.2037
MOG-G-CCM GDSC1 7.5305 8.3338 7.3694 6.9854
CAS-1 GDSC1 7.5573 8.0043 7.5157 5.8075
D-392MG GDSC1 7.5589 8.2261 7.4424 6.3109
SF295 GDSC1 7.562 8.0713 7.5008 5.8825
KNS-81-FD GDSC1 7.5881 8.2338 7.4704 5.9574
T98G GDSC1 7.6603 8.4047 7.4739 5.5697
A-172 GDSC1 7.8057 9.059 7.301 6.2593
42-MG-BA GDSC1 7.8701 8.8948 7.4402 4.9089
YKG-1 GDSC1 7.9274 8.9018 7.4872 4.3151
DBTRG-05MG GDSC1 8.0173 8.9583 7.5352 3.6038
D-502MG GDSC1 8.1075 9.3333 7.4207 4.1939
NMC-G1 GDSC1 8.2209 10.5853 6.8865 8.0077
Daoy GDSC1 8.2754 9.6983 7.368 4.0709
ONS-76 GDSC1 8.5083 12.3231 6.246 11.9371
Onda 10 GDSC1 8.6234 10.8123 7.0734 5.3327
M059J GDSC1 8.8152 10.8566 7.1805 4.0373
D-336MG GDSC1 8.8954 11.2775 7.0339 4.9172
Onda 11 GDSC1 8.931 11.2114 7.0881 4.4342
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 6.4056 7.4301 6.3761 20.1173
TGBC24TKB GDSC1 6.5085 7.3769 6.4907 18.7562
TGBC1TKB GDSC1 6.6863 7.3791 6.6766 16.4825
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1 5.6789 6.5782 5.6761 29.0309
AN3-CA GDSC1 6.0087 7.0834 5.9923 24.9948
KLE GDSC1 6.6679 7.6542 6.624 16.9323
EN GDSC1 7.1002 7.7838 7.0674 11.4579
MFE-296 GDSC1 7.2357 14.2983 4.1932 28.8882
ESS-1 GDSC1 7.486 7.956 7.4504 6.6569
MFE-280 GDSC1 7.4958 10.6136 6.2524 15.6346
MFE-319 GDSC1 7.5341 9.2261 6.9657 10.0173
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCZ GDSC1 5.5439 6.07 5.5439 30.7008
TK-10 GDSC1 6.0588 7.6557 5.9646 24.8703
SW13 GDSC1 6.2951 7.7305 6.2054 21.8905
SN12C GDSC1 6.3453 7.6509 6.2761 21.1286
KTCTL-26A GDSC1 6.4466 7.5594 6.4015 19.706
LB2241-RCC GDSC1 6.4565 8.1634 6.2682 20.539
OS-RC-2 GDSC1 6.4582 7.1674 6.4528 19.3063
RCC10RGB GDSC1 6.4607 7.7929 6.3718 19.8176
LB1047-RCC GDSC1 6.4752 7.8097 6.3837 19.6533
KTCTL-1M GDSC1 6.4826 7.7629 6.4022 19.4866
A-704 GDSC1 6.489 7.1912 6.4834 18.9228
KTCTL-140 GDSC1 6.499 7.4011 6.4783 18.894
HA7-RCC GDSC1 6.582 7.3257 6.5719 17.7882
KTCTL-21 GDSC1 6.6936 8.0268 6.5668 17.1637
KMRC-20 GDSC1 7.156 13.9957 4.2726 28.8808
BFTC-909 GDSC1 7.1769 8.1417 7.0594 11.0721
769-P GDSC1 7.1932 8.1173 7.0849 10.8055
786-O GDSC1 7.1988 7.9034 7.1499 10.3323
KTCTL-13 GDSC1 7.2071 8.2185 7.0665 10.8569
BB65-RCC GDSC1 7.2649 12.5279 5.0976 24.2902
UO-31 GDSC1 7.2662 8.5791 6.9908 11.0904
KMRC-1 GDSC1 7.3664 7.8544 7.3422 8.0753
SW156 GDSC1 7.4682 8.3579 7.2939 7.8529
CAL-54 GDSC1 7.4733 8.0744 7.4033 7.0494
KTCTL-195 GDSC1 7.4941 8.1897 7.3866 7.0526
NCC021 GDSC1 7.5127 8.1498 7.4209 6.7105
LB996-RCC GDSC1 7.514 8.2693 7.3778 7.0098
ACHN GDSC1 7.6017 8.2028 7.497 5.6955
Caki-1 GDSC1 7.6099 8.684 7.296 7.1477
A-498 GDSC1 7.7602 10.9073 6.3419 13.8925
VMRC-RCW GDSC1 8.2035 10.0036 7.1624 5.9043
RXF 393L GDSC1 8.5237 11.3348 6.7464 8.1238
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC1 4.8616 6.3496 4.8486 39.3051
LoVo GDSC1 6.4561 7.9465 6.3294 20.1266
RKO GDSC1 6.9531 7.7592 6.9131 13.3433
SNU-407 GDSC1 7.1816 9.8536 6.3264 16.4548
COLO 320HSR GDSC1 7.2539 14.7913 3.9642 29.7528
LS411N GDSC1 7.2754 7.8736 7.2399 9.2866
HT-55 GDSC1 7.2849 8.1045 7.1888 9.5782
HT115 GDSC1 7.3271 7.9954 7.2669 8.8063
KM12 GDSC1 7.3513 8.0201 7.2865 8.5349
MDST8 GDSC1 7.3873 7.8262 7.3695 7.7727
SNU-C5 GDSC1 7.4051 8.4343 7.1963 8.8852
HCT 116 GDSC1 7.4392 7.9684 7.3964 7.2893
SW48 GDSC1 7.4471 12.0336 5.5057 21.0438
SW620 GDSC1 7.4517 7.9686 7.4099 7.1263
SW837 GDSC1 7.4643 8.1873 7.3553 7.4338
T84 GDSC1 7.4683 8.475 7.2454 8.2071
SNU-C2B GDSC1 7.476 8.4934 7.2455 8.1676
NCI-H747 GDSC1 7.4797 8.5041 7.2448 8.155
COLO 678 GDSC1 7.4828 8.0916 7.4082 6.9627
HCC2998 GDSC1 7.4885 8.1995 7.377 7.1507
CCK-81 GDSC1 7.4909 8.3069 7.3384 7.4139
GP5d GDSC1 7.4973 8.0098 7.4486 6.6041
CW-2 GDSC1 7.52 8.2434 7.3942 6.8613
SNU-175 GDSC1 7.5255 8.4081 7.3333 7.2744
SW626 GDSC1 7.5449 8.2706 7.41 6.617
LS513 GDSC1 7.5675 8.3914 7.384 6.6922
LS180 GDSC1 7.587 8.1664 7.495 5.7871
HCT 15 GDSC1 7.6571 8.3218 7.5068 5.341
CL-11 GDSC1 7.6608 8.5439 7.4113 6.0375
SW1463 GDSC1 7.6645 8.3561 7.4995 5.3585
NCI-H716 GDSC1 7.6725 8.6198 7.3878 6.1617
SNU-C1 GDSC1 7.7265 9.7706 6.8776 9.8921
CaR-1 GDSC1 7.7918 8.6966 7.466 5.0315
RCM-1 [Human ESC] GDSC1 7.861 8.4822 7.6351 3.4238
SW1116 GDSC1 7.9105 8.9751 7.4359 4.7838
LS123 GDSC1 7.9186 8.729 7.5656 3.7328
SW1417 GDSC1 7.9188 9.1411 7.3604 5.3459
SNU-1040 GDSC1 8.0805 9.6937 7.2193 5.8717
SW948 GDSC1 8.1623 9.5591 7.3512 4.5584
HT-29 GDSC1 8.1957 9.2698 7.5199 3.1341
LS1034 GDSC1 8.2426 9.9457 7.2212 5.3178
COLO205 GDSC1 8.2698 9.6215 7.4016 3.8278
SNU-61 GDSC1 8.5502 10.1833 7.3258 3.6237
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 10.254 12.1284 7.3788 0.7334
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC1 5.607 8.3903 5.2724 31.9534
Huh-7 GDSC1 5.896 6.9638 5.8834 26.3789
JHH-1 GDSC1 6.5434 7.7459 6.4718 18.6692
SNU-475 GDSC1 6.5969 7.0706 6.5963 17.5422
JHH-6 GDSC1 6.7596 7.1572 6.7592 15.5076
JHH-7 GDSC1 7.3017 15.8622 3.4728 31.3623
SNU-423 GDSC1 7.345 8.1185 7.2497 8.8231
HuH-1 GDSC1 7.3488 7.9106 7.3116 8.3808
SK-HEP-1 GDSC1 7.365 7.7879 7.3513 8.0246
JHH-2 GDSC1 7.4492 7.999 7.3992 7.2134
HLE GDSC1 7.4542 8.5438 7.2013 8.6029
SNU-398 GDSC1 7.5226 8.1931 7.4159 6.6927
SNU-387 GDSC1 7.5262 8.1296 7.4425 6.4849
Hep-G2/C3A GDSC1 7.6249 8.2509 7.5027 5.5339
SNU-449 GDSC1 7.9113 15.564 4.1438 26.4605
JHH-4 GDSC1 8.3258 17.1603 3.6884 26.8736
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1341 GDSC1 6.0837 8.0476 5.8955 25.1799
NCI-H446 GDSC1 6.2039 7.7975 6.0912 23.1816
NCI-H841 GDSC1 6.308 7.3522 6.2817 21.3166
NCI-H1581 GDSC1 6.5421 7.6945 6.4807 18.6184
LK-2 GDSC1 6.5705 7.1635 6.5678 17.8857
NCI-H650 GDSC1 6.6119 7.2918 6.605 17.395
NCI-H810 GDSC1 6.6262 7.4986 6.602 17.3257
CAL-12T GDSC1 6.6329 7.9324 6.5259 17.7879
NCI-H847 GDSC1 6.6698 7.2951 6.6645 16.6604
NCI-H1105 GDSC1 6.7171 7.6012 6.6852 16.24
KNS-62 GDSC1 6.7194 7.2744 6.7162 16.0277
A-427 GDSC1 6.7456 8.2314 6.5616 16.9077
NCI-H1436 GDSC1 6.7666 7.9734 6.6611 16.1087
DMS 53 GDSC1 6.7731 7.6575 6.7366 15.5695
SK-LU-1 GDSC1 6.7923 7.7292 6.7448 15.4014
NCI-H510A GDSC1 6.8246 7.6756 6.789 14.9202
NCI-H1694 GDSC1 6.8583 7.6765 6.8251 14.483
NCI-H290 GDSC1 6.8599 7.7823 6.8078 14.5868
NCI-H720 GDSC1 6.8851 7.8798 6.8139 14.3984
Lu-99A GDSC1 6.8876 8.4667 6.6329 15.6367
NCI-H1304 GDSC1 6.897 7.6637 6.8686 13.968
NCI-H1703 GDSC1 6.9755 7.8918 6.9095 13.235
COR-L303 GDSC1 7.0156 7.9301 6.9439 12.7725
NCI-H524 GDSC1 7.0322 7.9544 6.9559 12.5964
SK-MES-1 GDSC1 7.0519 8.0426 6.9534 12.5009
NCI-H1355 GDSC1 7.1053 8.1458 6.9803 12.0165
NCI-H1792 GDSC1 7.1209 8.2104 6.9759 11.9613
IST-SL1 GDSC1 7.1255 8.0739 7.0245 11.5994
NCI-H1648 GDSC1 7.1453 9.9708 6.2355 17.293
NCI-H1573 GDSC1 7.1533 8.0131 7.0723 11.1163
IST-SL2 GDSC1 7.1549 8.7831 6.7886 13.1328
NCI-H1048 GDSC1 7.1953 7.9177 7.1428 10.3997
HCC78 GDSC1 7.2039 8.0113 7.1281 10.449
NCI-H727 GDSC1 7.2162 8.4669 6.9836 11.3987
NCI-H2135 GDSC1 7.2207 8.4616 6.9905 11.3254
NCI-H1793 GDSC1 7.2213 7.8759 7.1806 9.9967
NCI-H2081 GDSC1 7.2213 8.0529 7.1351 10.303
DMS 273 GDSC1 7.2231 7.9262 7.1711 10.0497
RERF-LC-MS GDSC1 7.2289 7.9904 7.1611 10.0833
SBC-3 GDSC1 7.234 8.2241 7.0936 10.5207
COR-L23 GDSC1 7.2473 13.4388 4.6304 26.84
BEN GDSC1 7.2649 9.691 6.4843 14.8928
PaCa-3 GDSC1 7.2668 8.2823 7.1082 10.2409
NCI-H1869 GDSC1 7.2733 8.0182 7.2019 9.5529
SBC-5 GDSC1 7.2735 8.109 7.1749 9.7377
NCI-H1435 GDSC1 7.2748 8.5233 7.0228 10.8134
NCI-H2196 GDSC1 7.2895 8.0391 7.2136 9.3818
NCI-H2722 GDSC1 7.295 8.4018 7.093 10.2003
NCI-H2141 GDSC1 7.2955 8.0749 7.2095 9.3758
NCI-H69 GDSC1 7.3099 8.2408 7.1697 9.5745
NCI-H292 GDSC1 7.3139 7.9956 7.2524 8.9799
NCI-H209 GDSC1 7.3211 8.7636 6.9685 10.9823
COR-L88 GDSC1 7.3278 8.875 6.9258 11.2684
NCI-H2066 GDSC1 7.3316 8.1699 7.2179 9.1182
NCI-H1876 GDSC1 7.357 8.1812 7.2416 8.8136
NCI-H2085 GDSC1 7.3573 8.7586 7.0077 10.5142
NCI-H2342 GDSC1 7.3583 8.1624 7.2494 8.7525
NCI-H661 GDSC1 7.3693 8.1793 7.2555 8.6498
NCI-H522 GDSC1 7.3802 9.2013 6.828 11.7615
NCI-H211 GDSC1 7.3822 8.015 7.3216 8.1214
NCI-H2869 GDSC1 7.3955 8.4309 7.1876 8.9973
NCI-H1915 GDSC1 7.4042 7.9972 7.3505 7.7998
NCI-H64 GDSC1 7.4045 7.8776 7.3789 7.6083
NCI-H1651 GDSC1 7.406 8.1842 7.2935 8.184
NCI-H1623 GDSC1 7.4101 8.1838 7.2981 8.129
Lu-134-A GDSC1 7.4252 8.5661 7.1617 9.0381
SW1271 GDSC1 7.4275 8.0867 7.3495 7.6752
EBC-1 GDSC1 7.4285 11.6912 5.6589 20.1212
LCLC-103H GDSC1 7.436 16.7894 3.1269 31.9738
NCI-H226 GDSC1 7.4373 7.8945 7.4111 7.2025
NCI-H2369 GDSC1 7.4382 7.8941 7.4122 7.1904
NCI-H838 GDSC1 7.4415 7.8589 7.4224 7.1037
NCI-H187 GDSC1 7.4436 7.8522 7.4259 7.0683
EMC-BAC-2 GDSC1 7.4438 8.2202 7.3212 7.7847
NCI-H23 GDSC1 7.4451 8.1583 7.3448 7.6115
HCC44 GDSC1 7.4456 8.589 7.1728 8.8561
NCI-H146 GDSC1 7.4488 8.2217 7.3261 7.7229
LC-2/ad GDSC1 7.4495 8.7985 7.0833 9.5063
LXF 289 GDSC1 7.4622 8.5543 7.205 8.5361
NCI-H2009 GDSC1 7.464 8.1234 7.3772 7.282
EPLC-272H GDSC1 7.4663 8.1937 7.3551 7.4242
UMC-11 GDSC1 7.4712 10.849 6.1139 16.7591
NCI-H1734 GDSC1 7.4738 13.5264 4.7869 25.1017
NCI-H2595 GDSC1 7.474 8.0714 7.4049 7.0343
NCI-H647 GDSC1 7.4796 8.2904 7.3329 7.5123
RERF-LC-KJ GDSC1 7.4821 7.9392 7.4502 6.6806
NCI-H2795 GDSC1 7.4822 8.2333 7.3575 7.3224
NCI-H2087 GDSC1 7.4836 8.2571 7.35 7.3689
NCI-H1770 GDSC1 7.4883 7.9454 7.4554 6.6099
ABC-1 GDSC1 7.4933 8.8179 7.1182 9.0366
NCI-H526 GDSC1 7.4939 7.9936 7.4495 6.6173
HCC15 GDSC1 7.4959 8.1503 7.4025 6.9307
NCI-H1568 GDSC1 7.4987 8.2067 7.3852 7.0375
LCLC-97TM1 GDSC1 7.5101 8.464 7.2934 7.6453
NCI-H460 GDSC1 7.5106 8.1615 7.4145 6.7663
NCI-H196 GDSC1 7.5119 7.8897 7.4929 6.2231
NCI-H2029 GDSC1 7.5143 8.5955 7.2402 8.0199
A-549 GDSC1 7.5148 8.1761 7.4138 6.7494
CPC-N GDSC1 7.5172 8.3133 7.3637 7.0949
NCI-H1781 GDSC1 7.5188 16.2158 3.4845 30.4948
NCI-H1650 GDSC1 7.5202 8.2037 7.4094 6.7514
HOP-62 GDSC1 7.5293 8.8133 7.1562 8.582
NCI-H2405 GDSC1 7.5296 9.3381 6.9075 10.4847
Lu-65 GDSC1 7.5356 8.2193 7.4201 6.5935
NCI-H1563 GDSC1 7.5372 15.1861 4.0143 28.4245
NCI-H2461 GDSC1 7.5374 8.2101 7.4255 6.5455
IA-LM GDSC1 7.5376 8.7842 7.1779 8.3786
NCI-H2171 GDSC1 7.5396 8.1523 7.449 6.3673
NCI-H1666 GDSC1 7.5423 8.2298 7.4232 6.5362
NCI-H596 GDSC1 7.5433 8.1354 7.459 6.2771
NCI-H2803 GDSC1 7.5439 8.2206 7.4285 6.49
NCI-H1944 GDSC1 7.5503 11.3933 5.9154 17.855
NCI-H2030 GDSC1 7.5597 8.3069 7.4111 6.5335
Lu-139 GDSC1 7.562 8.1353 7.4793 6.0326
NCI-H82 GDSC1 7.5665 8.0581 7.5099 5.7947
Lu-135 GDSC1 7.5709 8.2847 7.4319 6.3246
HARA [Human squamous cell lung carcinoma] GDSC1 7.5711 8.1289 7.4913 5.8993
COLO 668 GDSC1 7.5738 8.422 7.3775 6.7091
HCC827 GDSC1 7.582 8.1999 7.477 5.9421
NCI-H2373 GDSC1 7.5885 8.2082 7.4808 5.8809
Lu-165 GDSC1 7.6083 8.1958 7.5067 5.5908
NCI-H2110 GDSC1 7.6114 8.6494 7.3136 7.0073
LOU-NH91 GDSC1 7.6309 8.4365 7.4298 6.0409
NCI-H322M GDSC1 7.6385 8.4934 7.412 6.1379
NCI-H1975 GDSC1 7.6405 8.7338 7.3028 6.9555
NCI-H2228 GDSC1 7.6475 8.5962 7.374 6.3822
Calu-6 GDSC1 7.6476 8.9584 7.2028 7.6915
LB647-SCLC GDSC1 7.65 8.3851 7.472 5.6333
NCI-H2347 GDSC1 7.6576 8.812 7.2824 7.035
NCI-H2170 GDSC1 7.6588 15.1146 4.1546 27.3644
NCI-H2172 GDSC1 7.6727 8.1674 7.5864 4.6819
NCI-H1755 GDSC1 7.7198 8.6466 7.4213 5.6915
NCI-H2731 GDSC1 7.726 13.8479 4.8447 23.7846
NCI-H1688 GDSC1 7.7334 8.5467 7.4819 5.1667
PC-14 GDSC1 7.7578 8.7673 7.3996 5.6919
NCI-H2804 GDSC1 7.7802 9.1112 7.2521 6.746
Ms-1 GDSC1 7.7804 9.4252 7.097 7.9591
COR-L321 GDSC1 7.7961 8.536 7.5476 4.3826
NCI-H2023 GDSC1 7.8158 8.6645 7.504 4.6342
ChaGo-K-1 GDSC1 7.8235 16.5025 3.6008 28.9572
COR-L311 GDSC1 7.8631 8.8135 7.4741 4.6714
NCI-H513 GDSC1 7.9013 8.9789 7.426 4.8974
NCI-H1155 GDSC1 7.9075 9.2351 7.3038 5.8348
NCI-H1299 GDSC1 7.9368 8.9356 7.4785 4.3471
NCI-H1838 GDSC1 7.942 8.8837 7.5089 4.0887
EKVX GDSC1 7.9849 10.1678 6.9035 8.6985
NCI-H2122 GDSC1 7.9859 8.9262 7.5251 3.7971
RERF-LC-Sq1 GDSC1 7.9868 9.4453 7.2663 5.8345
NCI-H441 GDSC1 8.0075 13.9367 5.0379 21.6421
EMC-BAC-1 GDSC1 8.0725 9.9274 7.0961 6.8699
NCI-H3255 GDSC1 8.0825 14.4316 4.8527 22.3865
NCI-H1836 GDSC1 8.116 9.6379 7.2756 5.3064
NCI-H358 GDSC1 8.1223 9.7246 7.2374 5.586
SW1573 GDSC1 8.2071 10.0439 7.1451 6.0279
NCI-H1437 GDSC1 8.2494 9.6569 7.3691 4.1422
NCI-H2810 GDSC1 8.2658 10.7953 6.8173 8.3976
Calu-3 GDSC1 8.3731 10.1589 7.2135 4.9753
NCI-H2291 GDSC1 8.3738 10.2663 7.1613 5.3771
DMS 114 GDSC1 8.3912 10.5846 7.0175 6.4394
HCC33 GDSC1 8.4203 9.9264 7.3606 3.7088
COR-L105 GDSC1 8.5185 10.5564 7.1239 5.2416
SHP-77 GDSC1 8.5817 10.1418 7.3664 3.241
NCI-H345 GDSC1 8.7611 9.8324 7.6133 1.1617
SBC-1 GDSC1 8.8302 10.5889 7.3146 3.0357
NCI-H2444 GDSC1 9.5795 10.6488 7.6533 0.2323
NCI-H1993 GDSC1 9.5936 11.4241 7.3632 1.4342
NCI-H1092 GDSC1 9.8357 12.61 6.9853 3.308
NCI-H2818 GDSC1 10.2865 12.1546 7.3823 0.6984
NCI-H2591 GDSC1 10.6455 12.4231 7.424 0.3771
NCI-H3122 GDSC1 11.245 13.0023 7.4388 0.1714
NCI-H520 GDSC1 11.3121 23.298 2.9045 21.5836
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 7.5001 9.1511 6.9688 10.1442
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-1 GDSC1 5.4003 6.1025 5.4001 32.4977
KYSE-270 GDSC1 5.4944 6.3136 5.4935 31.3252
TE-5 GDSC1 5.8152 6.6065 5.8135 27.3204
KYSE-510 GDSC1 6.316 6.8143 6.3158 21.0514
KYSE-520 GDSC1 6.3256 8.1795 6.1207 22.2827
TE-11 GDSC1 6.4432 6.9223 6.4428 19.4627
T.T GDSC1 6.4593 9.3185 5.8379 23.4885
TE-8 GDSC1 6.4603 7.2561 6.4502 19.3097
KYSE-410 GDSC1 6.4954 7.1557 6.4914 18.833
EC-GI-10 GDSC1 6.4998 7.1154 6.4971 18.7692
OE21 GDSC1 6.5486 7.2738 6.5406 18.1924
KYSE-150 GDSC1 6.6422 7.085 6.6417 16.9752
KYSE-140 GDSC1 6.6598 10.7474 5.3954 25.3331
COLO 680N GDSC1 6.661 7.1834 6.6593 16.748
KYSE-180 GDSC1 6.6838 8.5935 6.367 18.6071
TE-4 GDSC1 6.7753 7.6557 6.7392 15.5396
KYSE-450 GDSC1 6.9806 7.6011 6.9657 12.8367
KYSE-70 GDSC1 7.0418 10.7884 5.7444 21.2529
TE-15 GDSC1 7.4497 8.874 7.0489 9.7645
OE19 GDSC1 7.4911 8.0484 7.4307 6.7615
OE33 GDSC1 7.5492 9.1018 7.0396 9.3823
TE-9 GDSC1 7.6135 8.2179 7.5036 5.5861
TE-10 GDSC1 8.3547 10.3546 7.1036 5.8834
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TOV-112D GDSC1 6.3881 7.3794 6.3634 20.3049
OAW28 GDSC1 6.4707 7.3517 6.4534 19.2259
OAW42 GDSC1 6.5264 6.8846 6.5264 18.4198
Caov-4 GDSC1 6.5483 10.4676 5.4163 25.7651
OVCAR-8 GDSC1 6.6242 7.8519 6.5362 17.769
IGROV-1 GDSC1 6.682 7.7703 6.6172 16.893
OVCAR-3 GDSC1 6.7066 9.3047 6.1003 20.3868
JHOS-4 GDSC1 6.7949 8.141 6.6437 16.0668
OV-90 GDSC1 6.9186 7.7181 6.8832 13.7443
OVK18 GDSC1 7.0621 7.8898 7.0043 12.0989
Caov-3 GDSC1 7.0844 7.8821 7.0304 11.7949
OVKATE GDSC1 7.1131 9.4982 6.4258 16.0315
FU-OV-1 GDSC1 7.1573 8.0883 7.0548 11.2134
TYK-nu GDSC1 7.1749 7.841 7.1375 10.5548
Kuramochi GDSC1 7.2061 8.1615 7.0846 10.736
EFO-21 GDSC1 7.3485 8.0028 7.2883 8.5387
TOV-21G GDSC1 7.4537 8.059 7.3867 7.2728
RMG-I GDSC1 7.4673 12.6615 5.2117 22.7694
OV56 GDSC1 7.5203 7.9 7.5 6.1269
EFO-27 GDSC1 7.5356 8.1353 7.4507 6.3762
JHOS-2 GDSC1 7.5912 8.0394 7.5425 5.4328
OVISE GDSC1 7.5976 7.9924 7.5629 5.2573
ES-2 GDSC1 7.7896 8.553 7.5332 4.5212
OC 314 GDSC1 7.7962 8.3669 7.6278 3.7677
SK-OV-3 GDSC1 7.9849 8.8891 7.5428 3.6606
DOV13 GDSC1 7.9936 8.9842 7.5026 3.9461
OVCAR-5 GDSC1 8.2797 10.1517 7.1474 5.776
OVCAR-4 GDSC1 9.7175 15.6325 5.503 13.3755
A2780 GDSC1 10.345 12.0109 7.4575 0.4205
OVTOKO GDSC1 10.3962 12.128 7.435 0.4604
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-4 GDSC1 6.1749 7.2002 6.1566 22.9288
HuP-T4 GDSC1 6.5811 7.3397 6.57 17.8063
SW1990 GDSC1 6.853 7.8068 6.7952 14.7105
Capan-1 GDSC1 6.8656 7.7356 6.8228 14.4547
Panc 02.03 GDSC1 7.0268 8.0365 6.9277 12.8176
MIA PaCa-2 GDSC1 7.1062 7.9101 7.0475 11.5542
PaTu 8902 GDSC1 7.1205 7.8235 7.0819 11.2424
DAN-G GDSC1 7.1832 8.037 7.0982 10.7701
SUIT-2 GDSC1 7.3755 8.4771 7.1476 9.3908
PaTu 8988t GDSC1 7.3895 7.8496 7.368 7.7689
KP-1N GDSC1 7.4358 8.2131 7.3153 7.8691
HPAC GDSC1 7.5172 7.9761 7.4795 6.2813
MZ-PC-1 GDSC1 7.5407 8.7297 7.2061 8.1502
Panc 08.13 GDSC1 7.5795 8.3741 7.4039 6.4856
YAPC GDSC1 7.5944 7.9777 7.5632 5.2737
Hs 766T GDSC1 7.6073 8.2964 7.4654 5.8949
AsPC-1 GDSC1 7.6679 8.4627 7.4556 5.6696
Panc 10.05 GDSC1 7.7597 8.5198 7.5202 4.7549
SU.86.86 GDSC1 7.9979 9.8221 7.0872 7.2057
CFPAC-1 GDSC1 8.0333 9.1638 7.4456 4.2528
Panc 03.27 GDSC1 8.4621 9.8173 7.4416 2.9843
HuP-T3 GDSC1 8.5648 10.0403 7.4034 3.0098
Capan-2 GDSC1 8.6079 10.1798 7.3655 3.1829
PL4 GDSC1 8.8344 10.5136 7.3517 2.7646
Panc 04.03 GDSC1 9.0552 11.7765 6.9021 5.4898
HPAF-II GDSC1 9.1703 11.1401 7.2646 2.6876
QGP-1 GDSC1 9.9677 11.4924 7.4989 0.4946
KP-3 GDSC1 10.1174 12.2352 7.2798 1.2696
PSN1 GDSC1 10.1177 15.0897 6.0262 9.0389
BxPC-3 GDSC1 10.1469 11.8401 7.4425 0.5764
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1 6.7902 7.7716 6.7344 15.4822
IST-Mes1 GDSC1 6.8277 7.7537 6.7785 14.9706
NCI-H2052 GDSC1 7.4684 8.1704 7.3658 7.3371
NCI-H28 GDSC1 7.5023 16.1715 3.4924 30.5293
NCI-H2452 GDSC1 7.5393 8.2647 7.4065 6.6719
MPP 89 GDSC1 7.5417 8.1429 7.4546 6.3166
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1 7.3636 13.8134 4.5473 26.7552
PC-3 GDSC1 7.3712 8.2607 7.2283 8.8313
DU145 GDSC1 7.3874 7.9545 7.3433 7.9448
22Rv1 GDSC1 7.3992 15.977 3.5004 30.8926
LNCaP clone FGC GDSC1 7.5236 10.2138 6.4747 13.8411
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 6.3358 7.19 6.3252 20.8687
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-5 GDSC1 6.1487 6.9661 6.1436 23.1732
A-388 GDSC1 6.1885 7.1071 6.1776 22.7124
GAK GDSC1 6.2044 7.0528 6.1971 22.4905
DJM-1 GDSC1 6.2964 7.1749 6.2853 21.3648
A-431 GDSC1 6.3166 7.2522 6.3006 21.1433
UACC-62 GDSC1 6.4021 6.9252 6.4015 19.9771
COLO 829 GDSC1 6.4062 7.1507 6.4001 19.9605
CP50-MEL-B GDSC1 6.4529 7.0522 6.451 19.3509
MZ-MEL-2 GDSC1 6.4762 7.2819 6.4649 19.1183
IGR-37 GDSC1 6.5096 6.946 6.5094 18.6309
WM1552C GDSC1 6.5715 7.2624 6.5649 17.8981
SK-MEL-2 GDSC1 6.5888 6.9572 6.5887 17.6406
COLO 679 GDSC1 6.7181 7.5094 6.6982 16.15
A-375 GDSC1 6.7201 8.5073 6.438 17.9115
A101D GDSC1 6.8691 7.4608 6.8611 14.1863
IGR-1 GDSC1 6.9387 10.246 5.9043 20.6348
CP66-MEL GDSC1 6.9439 7.778 6.8995 13.4869
RVH-421 GDSC1 6.9994 7.7232 6.9692 12.7004
Hs 938.T GDSC1 7.0088 7.8393 6.9576 12.7208
MZ-MEL-7 GDSC1 7.0189 7.876 6.9605 12.6426
Mel Ho GDSC1 7.0347 7.6839 7.013 12.2049
WM278 GDSC1 7.0376 7.9491 6.9631 12.5164
COLO 800 GDSC1 7.085 14.2194 4.0983 29.9148
451Lu GDSC1 7.0977 11.7141 5.3462 23.563
SK-MEL-3 GDSC1 7.1502 7.7286 7.1301 10.7504
CHL-1 GDSC1 7.1682 16.155 3.2101 32.7287
IPC-298 GDSC1 7.1965 7.7239 7.1802 10.1478
SK-MEL-1 GDSC1 7.2049 7.8882 7.1601 10.229
G-mel GDSC1 7.2365 8.4826 6.9989 11.1834
G-361 GDSC1 7.2405 8.5606 6.9714 11.3626
HT-144 GDSC1 7.2695 8.3771 7.0755 10.4594
LB2518-MEL GDSC1 7.406 8.0304 7.3432 7.8392
WM115 GDSC1 7.4148 7.8432 7.3963 7.4333
WT2-iPS GDSC1 7.4186 7.8354 7.4017 7.3755
LOX-IMVI GDSC1 7.439 7.9403 7.403 7.2467
HMV-II GDSC1 7.44 8.5009 7.205 8.6455
A2058 GDSC1 7.456 15.2086 3.9329 29.0698
UACC-257 GDSC1 7.4575 7.953 7.4201 7.0248
RPMI-7951 GDSC1 7.468 8.0657 7.4002 7.1005
SK-MEL-30 GDSC1 7.4682 7.9323 7.4366 6.8528
IST-MEL1 GDSC1 7.4814 8.1399 7.3905 7.0932
WM793 GDSC1 7.5022 14.7786 4.1874 27.8334
SK-MEL-28 GDSC1 7.5077 15.1177 4.023 28.504
MMAc-SF GDSC1 7.5184 8.0425 7.4622 6.3923
COLO 783 GDSC1 7.5833 8.2314 7.4663 6.0116
SK-MEL-24 GDSC1 7.7018 8.317 7.555 4.7642
MeWo GDSC1 7.7085 15.4114 4.0487 27.6245
Mel JuSo GDSC1 7.764 8.8207 7.3796 5.8206
M14 GDSC1 8.0294 13.858 5.0954 21.2317
LB373-MEL-D GDSC1 9.2392 10.4122 7.6044 0.6247
SH-4 GDSC1 9.7165 11.6985 7.3099 1.5671
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 6.6351 7.8345 6.5522 17.5994
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-UT-1 GDSC1 4.4049 5.734 4.4017 44.9533
VA-ES-BJ GDSC1 5.3173 5.9164 5.3172 33.5342
Hs 633.T GDSC1 5.3929 5.9963 5.3929 32.589
G-401 GDSC1 5.9556 7.5079 5.8814 26.0285
GCT GDSC1 6.3528 7.8046 6.2517 21.245
MES-SA GDSC1 6.4183 6.8606 6.4181 19.7723
TE 441.T GDSC1 6.4516 6.9502 6.4512 19.3575
Rh41 GDSC1 6.4949 6.9885 6.4943 18.8177
RKN GDSC1 6.58 7.1388 6.5781 17.7623
SW684 GDSC1 6.7001 7.2301 6.6979 16.2621
G-402 GDSC1 6.7965 8.1422 6.6452 16.0479
SK-LMS-1 GDSC1 6.8264 7.6091 6.8009 14.8323
EW-8 GDSC1 7.0951 9.3389 6.4811 15.7049
Rh30 GDSC1 7.3372 8.0537 7.2613 8.7866
SW982 GDSC1 7.3374 7.8664 7.3085 8.4683
HT-1080 GDSC1 7.429 7.9236 7.3959 7.352
RD GDSC1 7.4396 9.2647 6.8561 11.2784
KYM-1 GDSC1 7.4701 7.8905 7.4474 6.7698
MFH-ino GDSC1 7.4735 8.3373 7.3078 7.725
A-204 GDSC1 7.5312 9.5392 6.8118 11.2163
SW872 GDSC1 7.8513 9.0582 7.3424 5.7515
Rh18 GDSC1 8.0187 8.9184 7.5563 3.4326
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RF-48 GDSC1 5.6924 6.9356 5.6735 28.9638
NUGC-3 GDSC1 5.8327 6.6388 5.8307 27.1033
HGC-27 GDSC1 6.1659 6.9051 6.1631 22.9437
SNU-5 GDSC1 6.2755 7.0467 6.2703 21.589
Hs 746.T GDSC1 6.3567 6.8874 6.3561 20.545
SNU-1 GDSC1 6.3666 6.997 6.3647 20.4293
KATO III GDSC1 6.4363 7.5407 6.3934 19.8199
AGS GDSC1 6.4407 6.9093 6.4405 19.4924
OCUM-1 GDSC1 6.4553 7.6225 6.4002 19.6618
MKN1 GDSC1 6.51 7.3404 6.4956 18.7163
Fu97 GDSC1 6.5161 7.8478 6.4195 19.1761
HSC-39 GDSC1 6.5178 8.1462 6.3403 19.7017
SCH GDSC1 6.5186 6.9271 6.5185 18.5185
GCIY GDSC1 6.6508 7.497 6.6283 17.0075
MKN45 GDSC1 6.6902 7.4029 6.6789 16.4438
MKN7 GDSC1 6.7935 7.9463 6.6976 15.708
MKN28 GDSC1 6.8791 7.7738 6.8303 14.3254
NCI-N87 GDSC1 6.8988 10.6241 5.6863 22.3111
IM95 GDSC1 6.9282 8.2059 6.7682 14.466
NUGC-4 GDSC1 7.1739 8.0844 7.0741 10.9877
RERF-GC-1B GDSC1 7.2758 13.5848 4.5832 26.949
ECC10 GDSC1 7.3331 14.4818 4.1878 28.5107
TGBC11TKB GDSC1 7.3605 8.0968 7.2735 8.5728
23132/87 GDSC1 7.5081 8.1151 7.4278 6.687
SNU-16 GDSC1 7.5535 8.2623 7.4225 6.4829
SNG-M GDSC1 6.4958 7.3091 6.4833 18.881
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT GDSC1 5.4026 6.555 5.3952 32.5138
IHH-4 GDSC1 6.3198 6.9873 6.3174 21.0174
K5 GDSC1 6.488 7.1 6.4856 18.9149
KMH-2 GDSC1 6.5275 7.2998 6.517 18.4725
CGTH-W-1 GDSC1 6.5314 6.9903 6.531 18.3603
TT2609-C02 GDSC1 6.5852 7.5844 6.5464 17.933
8505C GDSC1 6.8205 7.8651 6.7469 15.2214
ML-1 [Human leukemia] GDSC1 7.2247 15.6368 3.5177 31.5104
B-CPAP GDSC1 7.2881 7.9707 7.2309 9.2731
BHT-101 GDSC1 7.351 7.93 7.3096 8.3815
ASH-3 GDSC1 7.421 7.9674 7.3767 7.5272
HTC-C3 GDSC1 7.4586 8.2976 7.3078 7.8027
WRO GDSC1 7.4958 8.1628 7.3981 6.9622
8305C GDSC1 7.9715 9.0065 7.4728 4.2618
CAL-62 GDSC1 8.0746 9.9013 7.1108 6.7467
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-38 GDSC1 4.6107 6.2967 4.5924 42.4577
LB771-HNC GDSC1 4.8126 7.5849 4.6254 40.7114
PE/CA-PJ15 GDSC1 5.3686 6.6047 5.3583 32.9565
SAS GDSC1 5.5148 6.2216 5.5145 31.0669
HO-1-u-1 GDSC1 5.5372 6.7266 5.5259 30.856
SCC-15 GDSC1 5.5387 6.9825 5.5083 30.9565
SCC-9 GDSC1 5.6197 6.248 5.6196 29.7544
OSC-20 GDSC1 5.9608 6.9535 5.951 25.5514
BB30-HNC GDSC1 6.1725 7.0083 6.1663 22.8824
BICR 22 GDSC1 6.1992 6.9166 6.1965 22.5269
BICR 31 GDSC1 6.2448 7.1718 6.2318 22.0217
BICR 10 GDSC1 6.2614 7.5517 6.2035 22.1031
HSC-2 GDSC1 6.284 7.8895 6.1563 22.2812
KOSC-2 GDSC1 6.3664 7.6418 6.3007 20.8419
HSC-4 GDSC1 6.3982 6.9219 6.3977 20.0255
HO-1-N-1 GDSC1 6.4092 7.7628 6.3224 20.4463
PCI-30 GDSC1 6.4188 7.1081 6.4148 19.7905
BICR 78 GDSC1 6.4382 7.8205 6.341 20.1528
BB49-HNC GDSC1 6.4483 7.4045 6.4243 19.5484
Detroit 562 GDSC1 6.459 7.3004 6.4456 19.3472
SCC-25 GDSC1 6.4843 7.2826 6.4733 19.0156
Ca9-22 GDSC1 6.5008 7.2774 6.4908 18.8033
HSC-3 GDSC1 6.5095 7.0589 6.5082 18.6393
OSC-19 GDSC1 6.5109 7.2333 6.5039 18.6578
KON GDSC1 6.5243 7.185 6.5198 18.4744
BHY GDSC1 6.5512 7.521 6.5192 18.3136
JHU-022 GDSC1 6.6059 8.3615 6.3665 19.0317
CAL-33 GDSC1 6.6345 7.3671 6.6236 17.1375
NCI-H3118 GDSC1 6.6955 9.6265 5.9474 21.5195
FaDu GDSC1 6.8403 7.662 6.8081 14.7015
CAL-27 GDSC1 7.1261 8.0108 7.0433 11.4677
SKN-3 GDSC1 7.1541 8.2982 6.9812 11.7437
PCI-15A GDSC1 7.1817 7.9666 7.1159 10.6589
PCI-04B GDSC1 7.1842 8.1784 7.0553 11.0604
PCI-06A GDSC1 7.2096 8.2085 7.0726 10.8007
SAT [Human HNSCC] GDSC1 7.3892 10.8368 6.0452 17.6054
DOK GDSC1 7.4361 8.2812 7.2901 8.0478
JHU-011 GDSC1 7.5495 8.3413 7.3862 6.7666
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC1 6.0457 7.1512 6.0255 24.5563
UM-UC-3 GDSC1 6.4024 7.313 6.3852 20.0788
KU-19-19 GDSC1 6.6834 7.2174 6.6812 16.4713
TCCSUP GDSC1 7.2214 7.82 7.1918 9.9221
T24 GDSC1 7.3744 8.0319 7.3083 8.2563
639V GDSC1 7.3985 7.7554 7.3906 7.5688
SW780 GDSC1 7.4452 8.1381 7.3519 7.5607
CAL-29 GDSC1 7.4591 8.002 7.4092 7.089
J82 GDSC1 7.4926 8.2022 7.3804 7.1043
647V GDSC1 7.5112 7.8795 7.4939 6.2208
SW1710 GDSC1 7.522 9.2499 6.9427 10.247
RT-112 GDSC1 7.6028 8.1705 7.5105 5.5931
RT-4 GDSC1 7.7571 8.817 7.3748 5.8868
HT-1197 GDSC1 7.8947 8.9966 7.4115 5.0371
HT-1376 GDSC1 7.9911 12.9066 5.5392 18.6644
5637 GDSC1 9.2093 11.7083 7.0305 4.2133
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SKG-IIIa GDSC1 6.2821 7.4506 6.2417 21.731
SiSo GDSC1 6.3902 7.8981 6.2699 20.9065
TC-YIK GDSC1 6.4781 7.317 6.4642 19.1117
PA-1 GDSC1 6.5136 7.4268 6.491 18.7229
NT2-D1 GDSC1 6.5923 7.2599 6.5865 17.6326
C-33 A GDSC1 6.6354 8.5411 6.3345 19.0951
NEC8 GDSC1 6.7229 8.2138 6.5426 17.1649
SKN GDSC1 6.7607 7.78 6.7006 15.8792
CAL-39 GDSC1 6.7967 7.7736 6.741 15.4001
HEC-1 GDSC1 6.8162 7.6536 6.7836 15.0056
OV17R GDSC1 6.8292 8.1307 6.6843 15.5958
BPH-1 GDSC1 6.9079 8.3418 6.7 15.0538
JEG-3 GDSC1 6.9552 8.2104 6.7961 14.1233
LB831-BLC GDSC1 7.0026 7.92 6.9323 12.9257
JAR GDSC1 7.1274 8.3532 6.9323 12.2331
KGN GDSC1 7.2741 8.1129 7.1743 9.7382
UWB1.289 GDSC1 7.2776 10.3773 6.1662 17.209
HT-3 GDSC1 7.2822 8.1637 7.1665 9.748
C-4-I GDSC1 7.2924 8.0162 7.2233 9.2992
NCC-IT GDSC1 7.3043 7.9493 7.254 9.0244
DoTc2 4510 GDSC1 7.3097 12.8312 4.9875 24.7143
JHOS-3 GDSC1 7.3191 8.3202 7.1501 9.6648
SW954 GDSC1 7.3463 8.1591 7.2376 8.9001
OVMIU GDSC1 7.3637 8.4077 7.1634 9.3365
DSH1 GDSC1 7.4036 8.9554 6.9654 10.6117
PWR-1E GDSC1 7.411 8.1675 7.3048 8.0775
SiHa GDSC1 7.4386 7.8537 7.4202 7.1356
HEY GDSC1 7.4446 8.3849 7.2581 8.2337
OVCA420 GDSC1 7.4568 8.0918 7.3798 7.3028
ME-180 GDSC1 7.4944 8.5242 7.2512 8.0347
ACC-OV7 GDSC1 7.5317 9.389 6.885 10.6493
HeLa GDSC1 7.5384 7.8724 7.5244 5.8596
OVCA433 GDSC1 7.5543 8.3409 7.3915 6.7036
SW962 GDSC1 7.6609 8.8795 7.2533 7.2441
MS751 GDSC1 7.6691 14.4133 4.5136 25.6877
OMC-1 [Human cervical carcinoma] GDSC1 7.7807 9.4386 7.0907 8.0073
Ca Ski GDSC1 7.9843 11.9963 5.9888 15.6328
SW756 GDSC1 8.0471 9.7332 7.1723 6.3586
PEO1 GDSC1 8.4467 10.2392 7.2273 4.6536
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 ClinicalTrials.gov (NCT03504423) Study Evaluating Efficacy and Safety of FFX Versus Combination of CPI-613 With mFFX in Patients With Metastatic Adenocarcinoma of the Pancreas. U.S. National Institutes of Health.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process. Cancer Metab. 2014 Mar 10;2(1):4.