Details of the Drug

General Information of Drug (ID: DM614BA)

Drug Name
Re-188-P-2045
Synonyms Neotide; RE-P2045; Rhenium 188-P-2045; Rhenium-188-labeled peptide (lung cancer), Antisoma; Rhenium-188-labeled peptide (lung cancer), Bryan Oncor/ Antisoma
Indication
Disease Entry ICD 11 Status REF
Lung cancer 2C25.0 Phase 1/2 [1]
Cross-matching ID
TTD ID
D0PX7X

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Somatostatin receptor type 2 (SSTR2) TTZ6T9E SSR2_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Lung cancer
ICD Disease Classification 2C25.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Somatostatin receptor type 2 (SSTR2) DTT SSTR2 9.79E-07 -0.38 -0.65
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 The somatostatin analog 188Re-P2045 inhibits the growth of AR42J pancreatic tumor xenografts. J Nucl Med. 2014 Dec;55(12):2020-5.