Details of the Drug

General Information of Drug (ID: DM6EKIV)

Drug Name

PMID30107136-Compound-Example16

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis	DB97.Z	Patented	[1]
Human immunodeficiency virus infection	1C62	Patented	[1]
Infectious disease	1A00-CA43.1	Patented	[1]
Solid tumour/cancer	2A00-2F9Z	Patented	[1]
------------------------------------------------------------------------------------

Drug Type

Small molecule immunotherapy

Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Programmed cell death protein 1 (PD-1)	TTNBFWK	PDCD1_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Hepatitis

ICD Disease Classification

DB97.Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Programmed cell death protein 1 (PD-1)	DTT	PDCD1	7.26E-01	-0.01	-0.03

Molecular Expression Atlas (MEA)

Jump to Detail Molecular Expression Atlas of This Drug

References

1	A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678.