Details of the Drug

General Information of Drug (ID: DM6MR82)

• Drug Name: 2-(1H-Imidazol-4-yl)phenol
• Synonyms: 2-(1H-Imidazol-4-yl)phenol; 19170-74-2; 2-(1H-Imidazol-5-yl)-phenol; 2-(1H-Imidazol-5-yl)phenol; CHEMBL457063; SCHEMBL1502109; BDBM24663; 2-(1H-imidazol-4-yl)phenol, 1

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 160.17
  Logarithm of the Partition Coefficient (xlogp); 1.4
  Rotatable Bond Count (rotbonds); 1
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 2
• Chemical Identifiers:
  Formula: C9H8N2O
  IUPAC Name: 2-(1H-imidazol-5-yl)phenol
  Canonical SMILES: C1=CC=C(C(=C1)C2=CN=CN2)O
  InChI: InChI=1S/C9H8N2O/c12-9-4-2-1-3-7(9)8-5-10-6-11-8/h1-6,12H,(H,10,11)
  InChIKey: BYAAMOMNSVKNMA-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 10307884
  ChEBI ID: CHEMBL457063
  TTD ID: D0NI8W
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Indoleamine 2,3-dioxygenase 1 (IDO1)	TTZJYKH	I23O1_HUMAN	Inhibitor	[1]

References

• [1] Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase. J Med Chem. 2008 Aug 28;51(16):4968-77.