Details of the Drug

General Information of Drug (ID: DM6N4PR)

Drug Name
Cerulenin
Synonyms
Helicocerin; Cerulenin, Cephalosporium caerulens; Oxiranecarboxamide, 3-(1-oxo-4,7-nonadienyl)-, (2R-(2-alpha,3-alpha(4E,7E)))-(9CI); (2R,3S)-2,3-Epoxy-4-oxo-7E,10E-dodecadienamide; (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide; (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide; (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide; (2R,3S)-3-nona-4,7-dienoyloxirane-2-carboxamide; (2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide; (2R-(2alpha,3alpha(4E,7E)))-3-(1-Oxonona-4,7-dienyl)oxirane-2-carboxamide; (2S)(3R)-2,3-Epoxy-4-oxo-7,10-dodecadienoylamide; (2S,3R)-2,3-epoxy-4-oxy-7,10-dodecadienoylamide; (2r,3s)-3-(nona-4,7-dienoyl)oxirane-2-carboxamide; 2,3-Epoxy-4-oxo-7,10-dodecadienamide; 2,3-Epoxy-4-oxo-7,10-dodecadienoylamide; 3-(1-Oxo-4,7-nonadienyl)oxiranecarboxamide; 3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide; 3-nona-4,7-dienoyloxirane-2-carboxamide
Indication
Disease Entry ICD 11 Status REF
Weight loss MG43.5 Approved [1]
Therapeutic Class
Antiinfective Agents
Affected Organisms
Humans and other mammalsFungiBacteriaMycobacterium tuberculosis
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 223.27
Logarithm of the Partition Coefficient (xlogp) 0.8
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C12H17NO3
IUPAC Name
(2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide
Canonical SMILES
C/C=C/C/C=C/CCC(=O)[C@@H]1[C@@H](O1)C(=O)N
InChI
InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)/b3-2+,6-5+/t10-,11-/m1/s1
InChIKey
GVEZIHKRYBHEFX-NQQPLRFYSA-N
Cross-matching ID
PubChem CID
5282054
ChEBI ID
CHEBI:171741
CAS Number
17397-89-6
UNII
MF286Y830Q
DrugBank ID
DB01034
TTD ID
D03ZFG
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fatty acid synthase (FASN) TT7AOUD FAS_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Eukaryotic translation initiation factor 2A (EIF2A) OTWXELQP EIF2A_HUMAN Post-Translational Modifications [3]
Piezo-type mechanosensitive ion channel component 1 (PIEZO1) OTBG1FU4 PIEZ1_HUMAN Gene/Protein Processing [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 144 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 3.7083 4.5258 3.7083 23.4317
JK1 CTRP2 5.3514 7.0386 5.2285 12.921
JM1 CTRP2 3.6722 6.1199 3.5843 23.9699
JVM-2 CTRP2 0.8227 3.6476 0.8052 42.6853
DoHH2 CTRP2 1.0796 6.0377 0.8016 41.5899
HuT 78 CTRP2 1.661 5.5982 1.5075 37.5191
SUP-T11 CTRP2 1.7028 4.7875 1.6491 36.9492
Ri-1 CTRP2 2.3635 5.8702 2.2188 32.8565
ME1 CTRP2 2.6 3.9606 2.5993 30.8102
Pfeiffer CTRP2 2.6116 4.6113 2.6003 30.7684
KMS-18 CTRP2 2.7124 4.2293 2.7104 30.0665
RCH-ACV CTRP2 2.7268 4.5616 2.7193 29.9892
Peer CTRP2 2.8071 4.2332 2.8057 29.4342
KHM-1B CTRP2 2.8287 5.3268 2.7822 29.4417
MOLT-13 CTRP2 2.8915 4.8056 2.8796 28.9076
ST486 CTRP2 3.0417 4.4336 3.04 27.8742
NALM-6 CTRP2 3.0755 4.4525 3.0739 27.6485
GA-10 CTRP2 3.1584 4.5027 3.1568 27.097
Mino CTRP2 3.2031 3.8558 3.2031 26.794
SU-DHL-6 CTRP2 3.219 5.2694 3.1939 26.7723
EB1 CTRP2 3.2204 4.9422 3.2111 26.7099
Hs 611.T CTRP2 3.2636 5.5317 3.2202 26.5374
697 CTRP2 3.3249 4.4405 3.3245 25.9848
SU-DHL-5 CTRP1 3.3257 4.0862 3.3257 55.4813
NU-DHL-1 CTRP2 3.3308 5.342 3.3053 26.0293
NCI-H929 CTRP2 3.3479 6.3875 3.1899 26.3681
KMS-34 CTRP2 3.39 4.4395 3.3897 25.5512
SUP-T1 CTRP2 3.4055 5.3156 3.3844 25.5176
SKM-1 CTRP2; CTRP1 3.4311 4.108 3.4311 25.2763
EoL-1 CTRP2 3.4469 4.1915 3.4469 25.1712
CA46 CTRP2 3.4678 4.9665 3.4623 25.0507
TALL-1 [Human adult T-ALL] CTRP2 3.4703 5.6374 3.4276 25.1591
Daudi CTRP2 3.4886 4.1622 3.4886 24.8937
NU-DUL-1 CTRP2; CTRP1 3.4909 5.1507 3.4802 24.9143
KE-97 CTRP1 3.4992 4.5701 3.4708 24.637
L-1236 CTRP2 3.5266 6.8797 3.2782 25.4948
DND-41 CTRP2 3.5431 4.9016 3.5399 24.5417
MOLP-8 CTRP2 3.545 4.2218 3.545 24.5186
A4/Fukuda CTRP2 3.5753 4.2258 3.5753 24.317
OCI-Ly3 CTRP2 3.6021 4.8025 3.6007 24.1429
Kasumi-2 CTRP2 3.6021 4.1314 3.6021 24.1386
KO52 CTRP2 3.6156 5.8747 3.5562 24.2491
MOLT-16 CTRP2 3.6169 4.7157 3.6162 24.0421
SUP-HD1 CTRP2 3.6169 5.0804 3.6111 24.0594
RL CTRP2 3.63 5.2063 3.6206 23.984
KMS-21-BM CTRP2 3.6401 6.9718 3.3795 24.7847
JeKo-1 CTRP2 3.6418 5.0815 3.6363 23.8927
HH [Human lymphoma] CTRP2 3.6484 5.9325 3.5841 24.0473
Karpas-422 CTRP2 3.6542 4.2377 3.6542 23.7916
BDCM CTRP2 3.6662 4.8101 3.6651 23.7152
MOTN-1 CTRP2 3.6967 6.067 3.618 23.7753
M-07e CTRP2 3.7057 4.2907 3.7057 23.449
MHH-CALL-4 CTRP2 3.7222 5.0959 3.7176 23.3545
OPM-2 CTRP2 3.7428 4.8788 3.7416 23.206
Ki-JK CTRP2 3.745 5.5252 3.7233 23.26
KMS-11 CTRP2; CTRP1 3.7657 6.2626 3.6626 23.4004
MM1.S CTRP2 3.7659 5.7251 3.73 23.1689
RS4;11 CTRP2 3.8135 5.271 3.8058 22.7572
SET-2 CTRP2 3.8169 4.3038 3.8169 22.7087
JJN-3 CTRP2 3.8701 5.0099 3.8685 22.3601
SEM CTRP2 3.9042 4.6422 3.9042 22.1279
KMS-12-BM CTRP2 3.9068 5.1322 3.9039 22.1202
DB CTRP2 3.922 6.0772 3.8568 22.2299
Ci-1 CTRP2 3.9246 5.6004 3.9048 22.058
BL-70 CTRP2; CTRP1 3.9439 4.751 3.9438 21.864
SK-MM-2 CTRP2 3.9472 7.75 3.4927 23.4398
F-36P CTRP2 3.9695 5.5418 3.9546 21.7431
NCO2 CTRP2 3.974 6.0974 3.9096 21.8808
OCI-AML-3 CTRP2; CTRP1 4.0297 5.1727 4.0275 21.2998
Ku812 CTRP1 4.09 5.1996 3.9904 16.738
SU-DHL-8 CTRP2 4.0937 5.9711 4.0512 21.0099
ALL-SIL CTRP2 4.0951 5.3479 4.0905 20.8725
Reh CTRP2 4.1 5.1982 4.0981 20.8306
KMS-20 CTRP2 4.117 6.6322 3.9751 21.1983
HT CTRP2; CTRP1 4.1245 5.4553 4.1173 20.6856
PL21 CTRP2; CTRP1 4.1281 6.29 4.0473 20.9121
GDM-1 CTRP2; CTRP1 4.1629 5.1752 4.1617 20.41
Granta-519 CTRP2 4.1641 7.6688 3.7545 21.8423
AML-193 CTRP2 4.1674 5.4318 4.1618 20.3948
MC116 CTRP2; CTRP1 4.1736 4.6245 4.1736 20.3345
THP-1 CTRP2; CTRP1 4.1761 5.8936 4.1453 20.4216
SU-DHL-1 CTRP2 4.1956 5.5618 4.1862 20.2194
RPMI-8226 CTRP2; CTRP1 4.199 5.8504 4.1728 20.2538
KE-37 CTRP2 4.2391 5.0364 4.2389 19.8994
MOLP-2 CTRP2 4.2721 6.792 4.11 20.2375
HDLM-2 CTRP2 4.2898 7.0577 4.0665 20.3367
HPB-ALL CTRP2 4.3272 5.6131 4.3191 19.3393
RPMI-8402 CTRP2 4.341 5.67 4.3309 19.2544
CML-T1 CTRP2 4.3615 5.4188 4.359 19.0926
P31/FUJ CTRP2 4.3637 5.7514 4.3504 19.1139
Mono-Mac-1 CTRP2 4.3806 6.5293 4.2797 19.3011
L-540 CTRP2 4.3817 5.6922 4.3717 18.9832
L-428 CTRP2 4.4436 6.3202 4.3804 18.7518
Karpas-299 CTRP2 4.5329 6.0987 4.5012 18.0496
EHEB CTRP2 4.5427 6.2449 4.4958 18.0362
Namalwa CTRP2 4.5434 6.6062 4.4416 18.2212
OCI-AML-2 CTRP2 4.5527 5.7763 4.5437 17.8414
P12-Ichikawa CTRP2 4.5593 5.9185 4.543 17.822
MOLM-13 CTRP2 4.5637 6.1891 4.5244 17.8707
DEL CTRP2 4.6238 5.0484 4.6238 17.3385
BV-173 CTRP2 4.6277 6.1861 4.5924 17.4313
SUP-B15 CTRP2 4.6328 6.5441 4.549 17.5638
Jurkat CTRP2 4.6591 6.7033 4.5485 17.4824
OCI-Ly19 CTRP2 4.6816 8.6146 3.9775 19.5143
NB4 CTRP2 4.7099 5.2171 4.7099 16.7652
WSU-DLCL2 CTRP2; CTRP1 4.7231 5.5066 4.7225 16.6795
HD-MY-Z CTRP2 4.8779 6.4071 4.832 15.8022
Raji CTRP2 4.8971 5.9108 4.8913 15.5386
L-363 CTRP2 4.8976 5.867 4.8931 15.5309
EJM CTRP2; CTRP1 4.8984 7.345 4.6529 16.3722
MOLM-6 CTRP2 4.9317 5.9491 4.9253 15.3104
U266B1 CTRP2 4.985 6.4073 4.9458 15.0669
OCI-M1 CTRP2 4.9972 6.7653 4.9025 15.1775
EM-2 CTRP2 5.0313 5.9312 5.0275 14.6388
U-937 CTRP2; CTRP1 5.0774 6.259 5.0581 14.3839
JURL-MK1 CTRP2 5.1087 6.3067 5.0868 14.1848
Kasumi-1 CTRP2 5.1125 6.4702 5.0736 14.2171
KCL-22 CTRP2 5.1628 6.7965 5.0758 14.0488
LP-1 CTRP2; CTRP1 5.1713 6.6318 5.1137 13.8899
SR CTRP2 5.173 6.8314 5.0799 14.0024
SU-DHL-4 CTRP2; CTRP1 5.2045 6.5798 5.157 13.6343
KYO-1 CTRP2 5.329 6.9522 5.2239 13.0067
SU-DHL-10 CTRP2 5.3663 6.5297 5.3358 12.4995
MOLM-16 CTRP2; CTRP1 5.4236 7.0185 5.3119 12.4011
HEL CTRP2 5.4779 6.313 5.4704 11.6787
RPMI-6666 CTRP2 5.5092 6.7918 5.4508 11.6444
NOMO-1 CTRP1 5.5411 6.1996 5.5388 23.8494
SIG-M5 CTRP2 5.5681 6.9497 5.4843 11.3412
MHH-CALL-3 CTRP2 5.5771 9.7457 4.4229 15.3988
TF-1 CTRP2 5.5965 6.9527 5.5145 11.1465
HL-60 CTRP2 5.633 7.577 5.3811 11.5188
LAMA-84 CTRP2 5.6507 6.898 5.5843 10.7307
HEL 92.1.7 CTRP2 5.6636 6.6121 5.6412 10.4931
K-562 CTRP2 5.7374 7.5034 5.5186 10.7039
Mono-Mac-6 CTRP2 5.9197 21.8347 -1.1919 31.2089
OCI-Ly10 CTRP2; CTRP1 6.1085 7.7271 5.8413 8.4259
AMO1 CTRP2; CTRP1 6.1274 7.2752 6.0139 7.7289
OCI-AML-5 CTRP2 6.1284 7.0128 6.0793 7.4924
CMK CTRP2 6.3211 7.3732 6.1953 6.4878
P3HR-1 CTRP2; CTRP1 6.5445 9.8253 5.324 9.4235
Toledo CTRP2 7.3224 16.2924 2.7747 17.8629
KMM-1 CTRP2 7.8005 15.518 3.5504 14.105
Karpas-620 CTRP2 8.016 10.5912 6.1498 3.2193
REC-1 CTRP2 9.9671 11.8369 6.6221 0.2223
⏷ Show the Full List of 144 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 5.1483 7.457 4.892 14.7521
TE8 CTRP2 5.7431 7.2429 5.6036 10.3764
TE-5 CTRP2 3.5664 5.5302 3.5372 24.4737
KYSE-150 CTRP2 4.2886 5.344 4.2865 19.5765
KYSE-140 CTRP2; CTRP1 4.3519 6.0082 4.3194 19.2574
EC-GI-10 CTRP2 5.0646 7.9215 4.6472 15.9041
TE-1 CTRP2 5.1943 7.121 5.0369 14.0885
KYSE-30 CTRP2 5.699 7.4643 5.4896 10.9243
KYSE-410 CTRP2; CTRP1 5.7336 7.7401 5.4335 11.032
OE21 CTRP2 5.758 8.5596 5.1342 12.1163
TE-10 CTRP2 5.9502 7.2856 5.8175 8.9759
KYSE-450 CTRP2; CTRP1 6.0678 7.5684 5.8551 8.4901
COLO 680N CTRP2 6.1265 8.5902 5.5001 9.7084
KYSE-70 CTRP2 6.1583 7.4753 5.985 7.7436
TE-14 CTRP2 6.3218 8.6831 5.6549 8.5951
TE-9 CTRP2 6.4151 7.7451 6.161 6.3495
OE19 CTRP2 6.4382 7.1312 6.3905 5.4268
TE-11 CTRP2 6.4926 7.3312 6.3952 5.2449
OE33 CTRP2 6.509 7.4848 6.361 5.3243
KYSE-180 CTRP2 6.5522 10.4733 5.0132 10.6928
KYSE-520 CTRP2 6.5535 9.2314 5.6211 8.1772
TE-6 CTRP2 6.7951 7.9624 6.4585 4.1813
KYSE-510 CTRP2 6.949 9.3361 5.9337 6.0033
TE-4 CTRP2 7.2084 9.8762 5.8881 5.6693
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.3783 7.2238 6.302 5.9274
SNU-410 CTRP2 4.2529 8.0572 3.7223 21.6964
HuP-T3 CTRP2 4.583 7.2501 4.3355 18.4748
HuP-T4 CTRP2; CTRP1 4.6573 6.0392 4.6366 17.1849
KP-3 CTRP2; CTRP1 4.7875 6.5201 4.7193 16.4807
KP-4 CTRP2 4.816 5.9718 4.8054 16.0945
Capan-2 CTRP2; CTRP1 5.0486 7.4138 4.7965 15.3986
Panc 03.27 CTRP2; CTRP1 5.0529 7.5585 4.7566 15.5324
PaTu 8988s CTRP2 5.2743 7.5061 5.0141 13.93
PK-59 CTRP2 5.3495 8.0457 4.9086 14.1063
Panc 10.05 CTRP2; CTRP1 5.4572 7.2058 5.3016 12.3346
Panc 05.04 CTRP2 5.474 6.7077 5.4267 11.8401
Panc 08.13 CTRP2 5.5803 7.9379 5.1963 12.3636
BxPC-3 CTRP2 5.6348 7.9106 5.2649 11.9494
YAPC CTRP2 5.7548 6.4838 5.747 9.8368
QGP-1 CTRP2; CTRP1 5.7695 7.9697 5.3866 11.1081
MIA PaCa-2 CTRP2 5.9474 7.4541 5.7629 9.1839
PK-45H CTRP2 6.0524 10.4595 4.5523 13.7212
Capan-1 CTRP2 6.1087 9.1409 5.2315 10.8301
PSN1 CTRP2 6.2348 7.1365 6.1678 6.8479
TCC-Pan2 CTRP2 6.2844 7.5924 6.0801 7.0237
AsPC-1 CTRP2 6.3308 8.7075 5.6526 8.5819
SNU-213 CTRP2 6.3445 7.3646 6.2235 6.3148
PaTu 8988t CTRP2 6.3505 7.2959 6.2511 6.1956
HPAF-II CTRP2 6.472 9.0856 5.6132 8.4001
DAN-G CTRP2 6.4778 8.1158 6.0691 6.5428
Panc 04.03 CTRP2 6.4911 10.5453 4.9217 11.206
SU.86.86 CTRP2 6.612 7.2464 6.5507 4.3201
SUIT-2 CTRP2; CTRP1 6.7031 7.267 6.6442 3.7061
KP-2 CTRP2 6.7253 8.9307 5.9289 6.5139
Hs 766T CTRP2 6.8595 9.1299 5.9554 6.1051
L3.3 CTRP2 7.0848 9.7195 5.8615 6.0255
CFPAC-1 CTRP2; CTRP1 7.2366 8.7525 6.4735 3.1568
SW1990 CTRP2 7.2587 10.3581 5.689 6.4088
HPAC CTRP2; CTRP1 7.2717 9.6609 6.0483 4.8751
Panc 02.03 CTRP2 7.4541 8.8726 4.7521 0.1511
PaTu 8902 CTRP2; CTRP1 8.1652 10.5347 6.2759 2.5152
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 9.2221 23.8103 0.5351 21.2121
HMCB CTRP2 3.7947 4.13 3.7947 22.8566
WT2-iPS CTRP2 3.8189 5.0059 3.817 22.7016
RVH-421 CTRP2 3.9861 6.7355 3.8115 22.1832
LOX-IMVI CTRP2 3.9963 6.3724 3.8925 21.8684
Hs 852.T CTRP2; CTRP1 4.5291 6.4024 4.4601 18.2028
G-361 CTRP2; CTRP1 4.6862 5.6355 4.6838 16.9309
Hs 895.T CTRP2 4.8687 9.4124 3.8472 19.4932
COLO 741 CTRP2; CTRP1 5.1024 7.8812 4.7022 15.5891
MDA-MB-435S CTRP2 5.1236 7.8581 4.7332 15.4123
Hs 944.T CTRP2; CTRP1 5.1268 6.4783 5.0878 14.1222
Malme-3M CTRP2 5.1864 7.9233 4.778 15.0636
MeWo CTRP2 5.2224 7.0862 5.0764 13.8611
SK-MEL-1 CTRP2; CTRP1 5.2759 6.2804 5.2633 13.0404
A-375 CTRP2; CTRP1 5.2992 7.0942 5.1581 13.3327
RPMI-7951 CTRP2 5.3616 6.4673 5.3375 12.5088
IGR-1 CTRP2 5.5491 9.8386 4.3523 15.7496
COLO 800 CTRP2 5.6271 8.1129 5.1794 12.2968
WM115 CTRP2 5.6403 7.8491 5.2935 11.8259
Hs 688(A).T CTRP2 5.6506 9.4567 4.6285 14.3955
COLO 792 CTRP2 5.6529 8.4106 5.0869 12.583
SK-MEL-3 CTRP2 5.6597 7.446 5.4526 11.1766
WM88 CTRP2 5.6879 7.801 5.3623 11.4308
SK-MEL-31 CTRP2 5.7032 6.4442 5.696 10.178
WM266-4 CTRP2 5.7116 7.3728 5.5316 10.733
SK-MEL-5 CTRP2; CTRP1 5.7447 6.9834 5.6689 10.1386
IPC-298 CTRP2 5.7691 6.7534 5.7359 9.8279
WM1799 CTRP2 5.7797 7.7845 5.4671 10.7738
Hs 294T CTRP2 5.811 7.8542 5.4749 10.6557
Mel Ho CTRP2 5.8119 7.8453 5.4792 10.6365
UACC-257 CTRP2 5.8207 9.1076 4.958 12.6501
Hs 940.T CTRP2 5.937 15.391 2.0268 23.3171
CJM [Human melanoma] CTRP2 6.0317 9.936 4.7826 12.8354
Mel JuSo CTRP2 6.1305 8.1117 5.7114 8.8655
COLO 829 CTRP2 6.1436 11.2936 4.2337 14.7984
SK-MEL-28 CTRP2; CTRP1 6.1452 7.6362 5.9144 8.0451
HT-144 CTRP2 6.1614 7.4965 5.9812 7.7484
SK-MEL-30 CTRP2 6.2541 7.1413 6.1876 6.718
IGR-37 CTRP2 6.2928 7.5274 6.1126 6.8774
Hs 934.T CTRP2 6.3304 8.242 5.8626 7.7433
K029AX CTRP2 6.3994 14.7502 2.7564 19.8474
A101D CTRP2 6.4051 7.113 6.3586 5.6427
Hs 936.T CTRP2; CTRP1 6.4316 7.7877 6.1612 6.3036
SK-MEL-2 CTRP2 6.4819 7.1205 6.4405 5.1141
UACC-62 CTRP2 6.5096 9.9488 5.2311 9.8864
A2058 CTRP2 6.5905 7.0655 6.569 4.322
WM793 CTRP2 6.5925 9.4571 5.5483 8.3882
IGR-39 CTRP2 6.7027 9.4897 5.6347 7.7829
SK-MEL-24 CTRP2 6.9165 9.7625 5.6931 7.0774
Hs 839.T CTRP2 7.2728 8.0655 6.8465 1.5225
WM983B CTRP2 7.3401 12.4159 4.7275 10.2693
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 4.2785 6.6998 4.1365 20.1242
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-BE(2) CTRP2 2.8667 5.5818 2.7963 29.269
SK-N-DZ CTRP2 3.7841 5.8815 3.7337 23.0968
SiMa CTRP2 4.3051 5.809 4.2863 19.5226
CHP-126 CTRP2 4.4247 6.5639 4.3211 19.0174
Kelly CTRP2 4.5298 5.7576 4.5209 17.9936
NH-6 CTRP2 4.6011 6.6909 4.488 17.8769
KP-N-SI9s CTRP2 5.1052 6.3826 5.0759 14.2329
CHP-212 CTRP2 5.1143 8.6097 4.4384 16.5567
SK-N-SH CTRP2 5.1483 7.2034 4.9652 14.4862
NB1 CTRP2 5.3058 6.4446 5.281 12.8825
SK-N-AS CTRP2 5.4336 7.841 5.074 13.2427
KP-N-YN CTRP2 5.613 9.1379 4.7333 14.0758
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 4.8647 6.1573 4.8439 15.8046
HuH-28 CTRP2 4.9523 6.4375 4.9073 15.304
SNU-245 CTRP2 5.2451 6.9696 5.1288 13.6043
HuCC-T1 CTRP2 5.5201 6.7474 5.47 11.5431
SNU-1196 CTRP2 5.9544 7.7989 5.6493 9.5895
SNU-869 CTRP2 6.4706 7.7974 6.1983 6.0542
SNU-308 CTRP2 7.2822 9.7752 5.9998 5.0591
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 3.4694 4.785 3.4672 25.0289
SK-N-MC CTRP2 3.788 4.3173 3.788 22.9008
MG-63 CTRP2 3.8912 5.119 3.8884 22.2234
SK-ES-1 CTRP2 4.0668 5.1301 4.0654 21.0499
SaOS-2 CTRP2 4.475 5.9266 4.4548 18.3964
Hs 888.T CTRP2 4.6714 9.2278 3.7193 20.5168
MHH-ES-1 CTRP2 4.8938 6.1607 4.8741 15.6074
G-292 clone A141B1 CTRP2 5.0665 7.0421 4.9172 14.9091
U2OS CTRP2; CTRP1 5.1297 7.6985 4.7945 15.1664
HOS CTRP2 5.2781 6.6731 5.2219 13.1746
CAL-78 CTRP2 5.2973 7.1616 5.1388 13.4078
SJSA-1 CTRP2 6.2121 7.5722 6.0096 7.4958
SW1353 CTRP2 6.2555 8.6512 5.6031 8.969
TC71 CTRP2 6.4985 7.6168 6.3003 5.5843
Hs 822.T CTRP2 6.5835 7.0217 6.5684 4.3459
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 71 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-157 CTRP2 1.7809 5.8799 1.5898 36.8391
HCC1500 CTRP2 3.3837 9.6901 2.1747 29.6514
SK-BR-3 CTRP2 3.6454 7.802 3.1478 25.5848
DU4475 CTRP2 3.6497 4.2256 3.6497 23.8217
Hs 578T CTRP2 3.6574 8.0505 3.0794 25.7891
HCC2218 CTRP2 3.6727 4.6664 3.6724 23.6696
Hs 578Bst CTRP2 3.8259 4.4904 3.8258 22.6492
MDA-MB-453 CTRP2 4.0009 5.3486 3.9945 21.5054
MDA-MB-361 CTRP2 4.4668 5.3492 4.466 18.3857
T-47D CTRP2 4.5344 6.1064 4.5021 18.042
HCC1143 CTRP2 4.5784 7.6914 4.1979 18.9899
MDA-MB-468 CTRP2 4.6403 6.3956 4.58 17.4328
BT-474 CTRP2 4.715 5.9097 4.7044 16.7669
BT-549 CTRP2 4.9022 7.313 4.6662 16.313
AU565 CTRP2 4.9966 7.1472 4.8145 15.4912
CAL-148 CTRP2 5.0095 5.8191 5.0077 14.777
HCC202 CTRP2 5.0116 7.58 4.7048 15.8447
CAL-51 CTRP2 5.1645 6.765 5.0835 14.0165
HCC38 CTRP2 5.1792 7.3269 4.9645 14.3953
HCC1954 CTRP2 5.227 7.4826 4.9699 14.2325
ZR-75-1 CTRP2 5.2324 6.2349 5.2211 13.3252
MCF-7 CTRP2; CTRP1 5.3596 7.9167 4.9669 13.8572
HCC1395 CTRP2 5.3819 7.4584 5.1461 13.1259
CAMA-1 CTRP2 5.5852 7.1851 5.4469 11.4215
HMC-1-8 CTRP2 5.6097 6.7326 5.5684 10.9168
CAL-85-1 CTRP2 5.7667 7.8134 5.4426 10.9033
HCC1937 CTRP2 5.8195 7.7902 5.5078 10.5068
HCC1428 CTRP2 5.8609 8.3519 5.3292 11.0794
ZR-75-30 CTRP2 5.9323 7.7074 5.6595 9.6134
BT-20 CTRP2 5.993 8.0914 5.5754 9.7657
HDQ-P1 CTRP2 6.0012 7.3306 5.86 8.668
HCC1806 CTRP2 6.0077 7.7624 5.7202 9.1698
MDA-MB-231 CTRP2 6.0367 8.1251 5.6076 9.5222
HCC1419 CTRP2 6.1334 8.9644 5.3375 10.3419
KPL-1 CTRP2 6.2858 6.895 6.2679 6.337
JIMT-1 CTRP2 6.3151 8.3824 5.7847 8.0922
CAL-120 CTRP2 7.3965 9.0795 6.4392 3.0063
BT 428 CTRP2 3.3772 5.6963 3.3237 25.8153
BT 239 CTRP2 3.8296 4.2655 3.8296 22.6245
BT 231 CTRP2 4.2154 6.0882 4.1671 20.2193
BT 131 CTRP2 4.3464 5.9956 4.3148 19.291
BT 145 CTRP2 4.6085 6.9443 4.4415 18.0175
BT 228 CTRP2 4.6348 5.9531 4.6191 17.3176
BT 271 CTRP2 4.6401 6.3195 4.5901 17.399
BT 139 CTRP2 4.8013 5.4961 4.801 16.1576
BT164 CTRP2 4.8598 6.829 4.7406 16.1773
BT 248 CTRP2 4.9714 7.3489 4.7314 15.8673
BT 245 CTRP2 5.1446 7.3041 4.9332 14.6132
BT 112 CTRP2 5.1689 6.9267 5.0555 14.1011
BT 187 CTRP2 5.332 7.0353 5.2082 13.053
BT 216 CTRP2 5.4255 7.6757 5.1229 13.0834
BT 359 CTRP2 5.4719 8.4001 4.9006 13.7964
BT 172 CTRP2 5.4761 7.2892 5.2992 12.2861
BT 504 CTRP2 5.4867 7.1826 5.34 12.1065
BT 286 CTRP2 5.5283 7.6757 5.2343 12.37
BT 330 CTRP2 5.6648 7.638 5.395 11.3747
BT 159 CTRP2 5.6652 7.0064 5.5776 10.7087
BT 333 CTRP2 5.7487 6.8996 5.69 10.0522
BT147 CTRP2 6.049 7.3498 5.9063 8.3562
BT 422 CTRP2 6.1141 7.5462 5.913 8.14
BT 340 CTRP2 6.1593 7.8277 5.857 8.2237
BT 416 CTRP2 6.1957 8.0591 5.8016 8.3389
BT 482 CTRP2 6.2668 7.7562 5.9993 7.3801
BT 179 CTRP2 6.43 9.1795 5.5278 8.8488
BT 498 CTRP2 6.4644 8.5408 5.8625 7.4044
BT 328 CTRP2 6.4649 7.4794 6.3154 5.6221
BT 224 CTRP2 6.48 8.1382 6.0613 6.568
BT 444 CTRP2 6.5108 7.2864 6.4288 5.0677
BT 232 CTRP2 6.749 7.5628 6.5873 3.79
BT 440 CTRP2 6.9975 8.1158 6.5803 3.2047
BT 320 CTRP2 7.3615 8.9513 6.4755 2.9165
⏷ Show the Full List of 71 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 5.5043 6.3676 5.4946 11.5105
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 3.7836 5.8492 3.7367 23.0884
U-118MG CTRP2 4.8948 7.3124 4.6583 16.3638
SF268 CTRP2 4.9081 7.2263 4.6968 16.1845
SF539 CTRP2 5.0523 6.5821 4.9937 14.6855
Daoy CTRP2 5.3275 6.783 5.2564 12.8978
SF295 CTRP2; CTRP1 5.4135 6.7411 5.3563 12.2771
ONS-76 CTRP2 5.4257 8.0259 4.9977 13.5534
GB-1 CTRP2 5.4303 6.4702 5.4096 12.0403
SNU-201 CTRP2 5.4854 6.1402 5.4837 11.6091
SNU-626 CTRP2 5.525 6.6631 5.4878 11.4661
GMS-10 CTRP2 5.6004 7.5684 5.3485 11.7353
SF126 CTRP2 5.6098 6.7372 5.5678 10.9186
M059K CTRP2 5.6347 8.3377 5.0977 12.5902
42-MG-BA CTRP2 5.6374 7.7344 5.3318 11.6901
KALS-1 CTRP2 5.7051 8.2568 5.2048 11.9843
SNU-738 CTRP2 5.7274 7.3628 5.5518 10.6116
Becker CTRP2 5.734 7.6361 5.4706 10.8922
CAS-1 CTRP2 5.8255 7.5733 5.5911 10.1771
YH-13 CTRP2 6.1399 9.3936 5.1444 11.1064
LN-229 CTRP2; CTRP1 6.2169 8.0125 5.8432 8.1196
U-251MG CTRP2 6.2757 8.3007 5.7807 8.2095
GOS-3 CTRP2 6.3141 9.4329 5.2952 10.0742
SNU-489 CTRP2 6.3393 7.6254 6.1268 6.6912
TM-31 CTRP2 6.3533 7.3135 6.249 6.1951
Hs 683 CTRP2 6.3572 8.0798 5.9608 7.2855
SNU-1105 CTRP2 6.3721 7.6945 6.1354 6.5668
DK-MG CTRP2 6.3733 8.1164 5.9616 7.2398
SW1088 CTRP2 6.3831 8.2988 5.8911 7.4941
8-MG-BA CTRP2 6.4089 8.4916 5.8298 7.6739
KNS-42 CTRP2 6.5055 7.0724 6.476 4.9152
U-87MG ATCC CTRP2 6.5188 7.3834 6.4068 5.1248
CCF-STTG1 CTRP2 6.5697 7.1474 6.5299 4.5244
KNS-81 CTRP2 6.6092 7.2714 6.5406 4.3653
A-172 CTRP2 6.67 12.1986 4.2641 13.5175
YKG-1 CTRP2 6.7137 7.76 6.4673 4.3534
DBTRG-05MG CTRP2 6.7226 7.4506 6.6032 3.8023
GaMG CTRP2; CTRP1 7.0298 8.0773 6.6291 2.9303
SNB-75 CTRP2 7.2927 11.5264 5.133 8.6735
KG-1-C CTRP2 7.965 11.7536 5.5468 5.7629
SW1783 CTRP2 8.0288 18.1105 2.4394 17.6663
T98G CTRP2 8.7443 15.4123 4.321 9.4938
NMC-G1 CTRP2 8.8998 10.4718 6.6991 0.4398
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-251 CTRP1 4.5172 5.3621 4.4075 10.7282
MFE-296 CTRP2 4.6387 6.4768 4.5663 17.4853
HEC-6 CTRP2; CTRP1 4.6412 5.3845 4.6409 17.2235
RL95-2 CTRP2 4.7273 6.2336 4.6925 16.7667
HEC-151 CTRP2; CTRP1 4.7511 6.5511 4.6751 16.75
KLE CTRP2; CTRP1 4.856 7.4657 4.571 16.7979
ESS-1 CTRP2 4.8761 7.3808 4.6182 16.5658
HEC-1-A CTRP2 4.9102 6.8559 4.7896 15.8469
JHUEM-2 CTRP2; CTRP1 5.0374 6.5844 4.9774 14.7893
HEC-265 CTRP2; CTRP1 5.0674 5.8532 5.0657 14.3913
JHUEM-7 CTRP2 5.2248 7.5472 4.9472 14.3226
HEC-59 CTRP2; CTRP1 5.3073 6.6715 5.2535 12.9721
HEC-108 CTRP2; CTRP1 5.3416 6.989 5.2294 12.948
JHUEM-1 CTRP2 5.4442 7.3225 5.2549 12.5427
HEC-50B CTRP2 5.4474 8.3822 4.8819 13.9357
MFE-319 CTRP2; CTRP1 5.4924 7.7016 5.1865 12.6525
AN3-CA CTRP2 5.6967 8.6183 5.0455 12.627
EN CTRP2 6.2823 8.6711 5.6209 8.8306
JHUEM-3 CTRP2 6.3982 7.9334 6.0659 6.7645
HEC-1-B CTRP2 6.5058 8.1107 6.0998 6.3486
EFE-184 CTRP2 7.0038 8.581 6.3571 4.1189
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 5.5153 6.8869 5.4398 11.6636
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 1.858 4.3536 -1.6272 1.5045
UO-31 CTRP2 4.9675 7.1856 4.7727 15.7301
RCC10RGB CTRP2; CTRP1 5.0253 6.129 5.013 14.7072
TUHR4TKB CTRP2 5.8424 6.8959 5.7919 9.4001
VMRC-RCW CTRP2; CTRP1 5.8467 7.6269 5.5957 10.0989
KMRC-20 CTRP2 6.0151 7.0558 5.9471 8.3125
BFTC-909 CTRP2 6.1512 7.1233 6.0798 7.4197
769-P CTRP2 6.1594 7.88 5.8365 8.3023
SNU-1272 CTRP2 6.1651 8.0584 5.7699 8.5445
KMRC-3 CTRP2 6.2221 7.9926 5.8569 8.0521
TUHR10TKB CTRP2 6.3717 7.22 6.2958 5.9697
OS-RC-2 CTRP2 6.4283 7.1486 6.3757 5.51
VMRC-RCZ CTRP2 6.4363 7.2674 6.3531 5.5669
CAL-54 CTRP2 6.5303 7.6047 6.3388 5.3484
786-O CTRP2 6.5578 7.1686 6.5121 4.6246
KMRC-1 CTRP2 6.6372 7.4673 6.5053 4.4146
Caki-1 CTRP2 6.6579 7.1777 6.6189 3.9351
ACHN CTRP2 6.6965 7.2162 6.6513 3.7007
KMRC-2 CTRP2 7.1259 11.3637 5.075 9.2394
Caki-2 CTRP2 8.116 10.3374 6.3371 2.3395
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C5 CTRP2; CTRP1 3.3173 4.9794 3.3087 26.0627
NCI-H747 CTRP2 3.3264 6.9158 3.0512 26.9158
LS513 CTRP2; CTRP1 3.473 5.6533 3.4289 25.1461
CW-2 CTRP2; CTRP1 3.9725 6.042 3.9149 21.8679
GP2d CTRP2; CTRP1 4.1006 5.5434 4.0895 20.8576
SW48 CTRP2; CTRP1 4.1966 5.6838 4.1814 20.2326
COLO 320 CTRP2; CTRP1 4.2024 6.4827 4.0957 20.507
SNU-81 CTRP1 4.2492 6.3992 4.1585 42.7289
CCK-81 CTRP2 4.384 7.5805 4.0215 20.2136
SNU-1033 CTRP2 4.4339 6.6348 4.3179 18.9995
SW948 CTRP2; CTRP1 4.4492 7.0137 4.2513 19.1867
LS123 CTRP2; CTRP1 4.5133 6.904 4.3473 18.6471
T84 CTRP2 4.5622 6.8879 4.4042 18.2936
SNU-407 CTRP2 4.7758 6.6472 4.6852 16.6358
SK-CO-1 CTRP2; CTRP1 4.7924 6.547 4.7202 16.4615
COLO 678 CTRP2; CTRP1 4.8664 6.7789 4.758 16.0955
SNU-C2A CTRP2; CTRP1 4.87 7.003 4.7125 16.2451
SNU-175 CTRP1 4.8767 6.5973 4.8009 33.8502
CL-11 CTRP2 4.9038 7.4699 4.6217 16.4699
COLO205 CTRP2; CTRP1 4.994 6.5112 4.9418 15.0515
DLD-1 CTRP2; CTRP1 5.1258 6.421 5.0935 14.106
SNU-61 CTRP2; CTRP1 5.1534 6.6752 5.0874 14.0383
C2BBe1 CTRP2; CTRP1 5.1857 7.456 4.9332 14.49
SW620 CTRP2; CTRP1 5.1998 6.7849 5.118 13.7846
SW1116 CTRP2 5.2215 6.9282 5.1123 13.7365
LoVo CTRP2; CTRP1 5.2276 7.1105 5.0759 13.8468
HCC-56 CTRP2 5.2292 8.4736 4.6145 15.5643
HCT 15 CTRP2 5.2675 7.0142 5.143 13.4845
HCT 116 CTRP2; CTRP1 5.2914 7.1383 5.1385 13.4267
KM12 CTRP2; CTRP1 5.3089 6.7203 5.2473 12.9883
HT-55 CTRP2; CTRP1 5.4324 6.7032 5.3828 12.1248
MDST8 CTRP2; CTRP1 5.4437 7.2974 5.2615 12.5205
NCI-H508 CTRP2; CTRP1 5.5783 7.0393 5.4756 11.3402
SNU-C1 CTRP2 5.5856 7.5844 5.3272 11.8576
RKO CTRP2; CTRP1 5.6087 7.2975 5.4415 11.3697
CL-40 CTRP1 5.626 7.143 5.4991 23.5645
LS180 CTRP2; CTRP1 5.6361 7.1949 5.4998 11.0759
LS411N CTRP2; CTRP1 5.665 7.0094 5.5767 10.7128
SW403 CTRP1 5.8227 7.6464 4.4564 4.628
HT115 CTRP1 5.8433 7.0312 5.7631 20.1106
RCM-1 [Human ESC] CTRP2; CTRP1 5.8942 6.9233 5.8429 9.0584
SNU-C4 CTRP2; CTRP1 5.9429 7.2712 5.8136 9.0121
LS1034 CTRP2 5.955 7.5225 5.7487 9.214
OUMS-23 CTRP2 6.0814 7.2816 5.9618 8.0564
HCT 8 CTRP2; CTRP1 6.1473 7.276 6.0353 7.5914
CL-34 CTRP1 6.1934 7.2427 6.0914 15.2821
SW480 CTRP1 6.2855 8.5674 5.6626 18.2631
NCI-H716 CTRP2 6.2904 8.1853 5.8462 7.9123
SNU-1040 CTRP1 6.371 7.0703 6.3283 12.2926
COLO201 CTRP2 6.388 7.2299 6.3109 5.8656
SNU-503 CTRP2 6.6874 7.5404 6.531 4.1761
HT-29 CTRP2; CTRP1 8.1957 11.9192 5.6324 5.0524
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP2; CTRP1 3.4484 4.9033 3.444 25.1761
JHH-2 CTRP2 4.3716 6.2975 4.3068 19.2366
HuH-6 CTRP2 4.7024 6.9903 4.5329 17.402
SNU-886 CTRP2 4.7654 6.8151 4.641 16.8237
Li-7 CTRP2 5.5151 7.6964 5.2129 12.4881
PLC/PRF/5 CTRP2 5.6098 7.7769 5.2869 11.9379
JHH-5 CTRP2 5.6405 7.7569 5.3271 11.6989
SNU-761 CTRP2 5.7486 6.4989 5.7398 9.8812
SNU-449 CTRP2; CTRP1 5.9963 7.1977 5.892 8.5669
Hep 3B2.1-7 CTRP2 6.0439 7.0693 5.9754 8.1227
Hep-G2 CTRP2; CTRP1 6.23 7.1842 6.1506 6.924
SNU-423 CTRP2 6.2733 7.5981 6.0661 7.1082
JHH-4 CTRP2 6.4007 8.0329 6.0261 6.9139
SNU-878 CTRP2 6.6666 7.7806 6.4096 4.7044
SNU-387 CTRP2 6.7661 12.2856 4.3052 13.1489
JHH-6 CTRP2; CTRP1 6.8368 7.1471 6.8202 2.6663
HuH-1 CTRP2 7.1374 7.8642 6.8321 1.8511
JHH-1 CTRP2 7.4 8.692 4.7948 0.1077
SK-HEP-1 CTRP2 7.5387 10.7274 5.7306 5.7186
HLF CTRP2 8.1369 12.3152 4.5743 4.201
SNU-475 CTRP2 8.9978 10.7082 6.6502 0.5081
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 159 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1963 CTRP1 0.7836 3.0738 0.7792 85.0512
NCI-H524 CTRP2 2.2426 4.0099 2.2393 33.198
NCI-H2085 CTRP2 2.7287 5.5233 2.6568 30.1922
NCI-H2087 CTRP2 3.1272 7.1798 2.7659 28.5274
NCI-H1105 CTRP2; CTRP1 3.1365 5.1956 3.1131 27.3156
SW1573 CTRP2 3.1924 7.0138 2.8806 27.9285
NCI-H1184 CTRP2 3.4689 6.6677 3.264 25.7266
NCI-H2171 CTRP2 3.5133 4.8807 3.5101 24.7403
NCI-H1694 CTRP2; CTRP1 3.5714 4.8662 3.569 24.3509
NCI-H1341 CTRP2 3.5968 5.0461 3.5915 24.1911
NCI-H889 CTRP2 3.6052 6.2362 3.4944 24.4944
NCI-H2029 CTRP2; CTRP1 3.6262 5.4833 3.6027 24.0566
Calu-1 CTRP2 3.6412 4.061 3.6412 23.8782
DMS 454 CTRP2 3.6574 8.3359 2.9812 26.1332
NCI-H82 CTRP1 3.6754 5.7953 3.3454 24.4241
NCI-H1092 CTRP2 3.7153 5.0976 3.7106 23.4007
NCI-H2286 CTRP2; CTRP1 3.7164 5.5537 3.6917 23.4603
RERF-LC-Ad2 CTRP2 3.7284 5.5033 3.7075 23.3677
NCI-H146 CTRP2 3.7486 5.4435 3.7318 23.2194
NCI-H1048 CTRP1 3.7555 4.9809 3.6788 21.3358
NCI-H1781 CTRP1 3.7613 5.1724 3.7554 49.2646
NCI-H1876 CTRP1 3.7669 6.5841 3.6029 49.2799
DMS 53 CTRP2 3.8005 6.3089 3.6925 23.1854
COR-L47 CTRP2 3.804 6.097 3.7284 23.0505
NCI-H1703 CTRP2 3.8121 5.3517 3.8015 22.7762
NCI-H1568 CTRP2; CTRP1 3.8322 5.3828 3.8209 22.6448
NCI-H1385 CTRP2 3.8448 5.3553 3.8349 22.5561
NCI-H1930 CTRP1 3.8735 6.7713 3.1534 24.6654
NCI-H211 CTRP2 3.9877 6.168 3.9147 21.8195
NCI-H3255 CTRP1 4.0093 5.5049 3.997 45.7681
NCI-H2106 CTRP2 4.0212 5.3251 4.0159 21.3666
NCI-H23 CTRP2; CTRP1 4.0667 6.4148 3.9612 21.4058
SCLC-21H CTRP1 4.0923 4.9635 4.092 44.5325
NCI-H1734 CTRP2 4.1727 7.8293 3.7121 21.9708
NCI-H810 CTRP2; CTRP1 4.2254 5.5086 4.2186 20.0124
NCI-H1581 CTRP2 4.2259 5.2466 4.2244 19.9916
NCI-H1155 CTRP2 4.2881 5.874 4.2639 19.6539
NCI-H2141 CTRP2; CTRP1 4.322 6.547 4.2133 19.7183
NCI-H1836 CTRP1 4.3278 7.2 4.0672 42.3366
VMRC-LCD CTRP2; CTRP1 4.3634 5.9768 4.3343 19.1692
NCI-H2081 CTRP2; CTRP1 4.366 6.4855 4.2716 19.3757
SHP-77 CTRP2; CTRP1 4.3664 6.3965 4.2865 19.3231
NCI-H522 CTRP2; CTRP1 4.3748 5.6686 4.3656 19.0262
COLO 668 CTRP2; CTRP1 4.4093 6.2769 4.3497 18.9677
HCC33 CTRP1 4.4463 5.0765 4.4088 11.1785
NCI-H1650 CTRP2 4.4666 5.53 4.4634 18.3955
LCLC-97TM1 CTRP2; CTRP1 4.4703 7.607 4.1072 19.6428
COR-L279 CTRP1 4.5171 5.3561 4.4093 10.7145
NCI-H526 CTRP2 4.5604 6.4862 4.4806 18.0318
NCI-H226 CTRP2 4.5632 5.1985 4.5631 17.742
NCI-H1563 CTRP2 4.6148 5.3235 4.6146 17.3989
EPLC-272H CTRP2; CTRP1 4.6177 7.3536 4.3442 18.3383
NCI-H1693 CTRP2 4.6184 6.8223 4.4798 17.8515
ChaGo-K-1 CTRP2; CTRP1 4.6377 6.9548 4.4708 17.8231
HCC4006 CTRP2; CTRP1 4.6495 6.887 4.4993 17.6853
COR-L88 CTRP2; CTRP1 4.7217 5.9636 4.7084 16.7312
DMS 273 CTRP2; CTRP1 4.7239 6.2231 4.6901 16.7859
HCC1171 CTRP2 4.7428 6.9162 4.5943 17.0591
COR-L51 CTRP1 4.784 7.3261 4.5298 36.2505
Calu-6 CTRP2; CTRP1 4.8002 6.8547 4.6703 16.6114
HCC1588 CTRP2 4.8008 6.3865 4.7525 16.3236
COLO 699 CTRP2; CTRP1 4.8444 6.4335 4.7928 16.045
LOU-NH91 CTRP2 4.8587 6.7289 4.7596 16.1143
NCI-H358 CTRP2; CTRP1 4.8911 6.0546 4.8785 15.6015
NCI-H1435 CTRP2; CTRP1 4.893 6.8824 4.7652 15.9867
NCI-H446 CTRP2 4.8933 6.605 4.8192 15.7971
COR-L23 CTRP1 4.932 5.8331 4.9288 32.5572
DMS 114 CTRP2 4.9352 8.0058 4.4776 16.9115
NCI-H1975 CTRP1 4.95 6.0768 4.5443 7.1632
NCI-H1299 CTRP2; CTRP1 4.9626 7.6177 4.6395 16.2301
NCI-H520 CTRP2 4.9823 7.1468 4.799 15.5906
Lu-99 CTRP2; CTRP1 4.9832 6.0894 4.9717 14.985
NCI-H2009 CTRP2; CTRP1 5.0135 6.387 4.9784 14.8632
HCC44 CTRP2; CTRP1 5.0148 6.3638 4.9823 14.8453
RERF-LC-KJ CTRP1 5.0528 6.194 4.5812 6.3459
NCI-H2291 CTRP2 5.0559 10.725 3.4526 20.4963
HCC1359 CTRP1 5.1174 6.186 5.1044 29.9793
HCC1438 CTRP2 5.1215 7.2226 4.9308 14.6918
LXF 289 CTRP2; CTRP1 5.131 6.8735 5.0257 14.3244
HCC1195 CTRP2; CTRP1 5.1461 6.6168 5.089 14.0562
NCI-H1915 CTRP2; CTRP1 5.1823 6.6933 5.1155 13.8485
HCC2108 CTRP2; CTRP1 5.1829 7.0816 5.0345 14.132
NCI-H727 CTRP2; CTRP1 5.2128 7.0559 5.0733 13.9015
COR-L95 CTRP2 5.2137 6.8009 5.13 13.6985
NCI-H650 CTRP2; CTRP1 5.2261 6.7902 5.1454 13.6056
HCC2279 CTRP2 5.2274 6.715 5.1604 13.5491
HCC15 CTRP2; CTRP1 5.2495 7.1669 5.0854 13.7455
NCI-H2342 CTRP2; CTRP1 5.2748 7.7598 4.9309 14.2364
NCI-H196 CTRP2 5.2818 7.0867 5.1411 13.4471
KNS-62 CTRP2; CTRP1 5.2988 6.8188 5.2186 13.1202
RERF-LC-A1 CTRP2 5.3249 7.232 5.1501 13.2829
NCI-H661 CTRP2; CTRP1 5.3303 7.2688 5.1459 13.2817
NCI-H1755 CTRP2; CTRP1 5.3351 7.037 5.2112 13.0327
Sq-1 CTRP2; CTRP1 5.3357 7.0812 5.2011 13.0669
HCC1833 CTRP2; CTRP1 5.3434 7.6598 5.0392 13.6338
SK-MES-1 CTRP2 5.3599 8.2941 4.8243 14.3987
CAL-12T CTRP2; CTRP1 5.3664 7.2176 5.1993 12.9795
NCI-H2196 CTRP2 5.3712 6.8571 5.2896 12.6436
NCI-H841 CTRP2; CTRP1 5.3952 7.4799 5.1539 13.058
NCI-H441 CTRP2; CTRP1 5.4405 6.8972 5.3567 12.1901
EKVX CTRP2 5.4605 7.6758 5.1608 12.8405
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 5.4838 6.385 5.4723 11.653
NCI-H1573 CTRP2; CTRP1 5.5146 8.1369 5.0503 13.1035
NCI-H1666 CTRP2; CTRP1 5.5337 7.1006 5.4123 11.7032
NCI-H2405 CTRP2; CTRP1 5.5587 8.044 5.1331 12.6646
HCC827 CTRP2; CTRP1 5.5839 7.2508 5.4276 11.4951
NCI-H2030 CTRP2; CTRP1 5.6108 7.062 5.5057 11.1327
EBC-1 CTRP2; CTRP1 5.6145 7.9273 5.2369 12.1133
NCI-H1623 CTRP2 5.6459 8.8174 4.9075 13.3027
DV-90 CTRP2; CTRP1 5.6534 7.6993 5.3614 11.5333
NCI-H1373 CTRP2; CTRP1 5.6807 7.8276 5.3449 11.5166
NCI-H596 CTRP1 5.6833 6.3527 5.6792 21.8313
NCI-H1838 CTRP2 5.6884 7.2166 5.551 10.7323
LCLC-103H CTRP2; CTRP1 5.6972 7.0411 5.6046 10.5139
NCI-H2444 CTRP2 5.722 6.1901 5.7216 10.0305
Calu-3 CTRP2; CTRP1 5.8021 6.816 5.7619 9.6325
RERF-LC-Ad1 CTRP2 5.8271 6.366 5.8255 9.3347
HCC2935 CTRP2; CTRP1 5.8572 7.2818 5.7171 9.6204
HOP-92 CTRP2 5.8763 11.7356 3.7684 17.2632
PC-14 CTRP2 5.8772 7.7757 5.5752 10.0884
HOP-62 CTRP2 5.8864 9.1959 4.9842 12.3788
NCI-H292 CTRP2 5.934 8.8015 5.21 11.3567
HCC78 CTRP2; CTRP1 5.9597 7.4752 5.7694 9.1237
RERF-LC-MS CTRP2 5.961 8.6171 5.319 10.8549
SW1271 CTRP2 6.0197 8.0506 5.6202 9.5199
HCC366 CTRP2 6.0202 7.8069 5.7167 9.1478
COR-L105 CTRP2 6.0376 8.3334 5.521 9.858
NCI-H2126 CTRP2; CTRP1 6.1471 7.4034 5.9964 7.7342
NCI-H1355 CTRP2; CTRP1 6.1699 8.7242 5.4837 9.6636
NCI-H2073 CTRP1 6.1735 7.5219 5.9804 16.2862
NCI-H322 CTRP2 6.2075 6.9258 6.18 6.891
NCI-H1869 CTRP2 6.2137 8.9868 5.4071 9.862
NCI-H1437 CTRP1 6.221 8.0228 4.5296 2.9934
T3M-10 CTRP2; CTRP1 6.2315 7.8474 5.9259 7.7597
LK2 CTRP2 6.2345 7.5915 6.0268 7.3669
NCI-H1395 CTRP2 6.2426 10.5195 4.7035 12.6636
SBC-5 CTRP2 6.3372 7.0962 6.2885 6.1024
NCI-H1793 CTRP2; CTRP1 6.3386 8.0394 5.9589 7.3421
NCI-H647 CTRP2 6.3739 10.8026 4.6876 12.431
NCI-H2122 CTRP2; CTRP1 6.4253 7.1716 6.3668 5.5511
A-549 CTRP2; CTRP1 6.4978 8.2746 6.018 6.6957
Lu-65 CTRP2; CTRP1 6.5106 7.5842 6.3257 5.4533
MOR/CPR CTRP2 6.5385 7.8285 6.2563 5.6455
NCI-H838 CTRP2 6.5738 11.2432 4.6527 12.1346
NCI-H2228 CTRP2 6.59 8.8736 5.828 7.2423
NCI-H2110 CTRP2; CTRP1 6.6189 10.8972 4.8645 11.1629
NCI-H2170 CTRP2 6.6485 11.319 4.6821 11.853
NCI-H1339 CTRP2 6.7323 7.2113 6.6917 3.446
LUDLU-1 CTRP2 6.7675 7.5852 6.5975 3.7001
NCI-H1944 CTRP2; CTRP1 6.9183 9.8551 5.6487 7.2595
NCI-H460 CTRP2; CTRP1 6.9239 7.7255 6.6961 2.9039
HCC95 CTRP2 7.2949 10.8654 5.4653 7.2779
NCI-H2023 CTRP2; CTRP1 7.3117 8.8343 6.4941 2.9291
NCI-H2172 CTRP2; CTRP1 7.3628 8.9009 6.5016 2.8049
SK-LU-1 CTRP2; CTRP1 7.3891 10.3981 5.7757 5.8
LC-1/sq-SF CTRP2; CTRP1 7.4736 10.1825 5.9507 4.9135
NCI-H1792 CTRP2; CTRP1 8.0077 11.0619 5.9162 4.1792
BEN CTRP2; CTRP1 8.2881 9.2372 6.9112 0.2375
Hs 888.Lu CTRP2 4.4173 7.4809 4.0882 19.871
⏷ Show the Full List of 159 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 2.842 5.6946 2.7563 29.4849
P-STS CTRP2 3.6798 5.5117 3.6565 23.6992
SYO-1 CTRP2 4.9499 6.8521 4.8335 15.5683
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 3.8203 4.2513 3.8203 22.6863
Aska-SS CTRP2 4.0526 5.7866 4.0249 21.2327
TE 441.T CTRP2 3.0735 5.2274 3.0456 27.7499
G-401 CTRP2; CTRP1 3.8627 6.4597 3.733 22.847
Rh41 CTRP2 3.9008 4.9643 3.8998 22.1537
KYM-1 CTRP2 3.9379 4.6498 3.9379 21.9032
TTC-709 CTRP2 4.0153 4.9994 4.0146 21.3908
A-204 CTRP2 4.0809 5.6118 4.0659 21.0017
SW982 CTRP2 4.2621 5.5179 4.2557 19.767
SK-UT-1 CTRP2 4.2624 7.174 4.0062 20.6364
TE 617.T CTRP2 4.2786 7.4242 3.9538 20.7758
GCT CTRP2 4.6868 6.5705 4.6027 17.2056
Hs 729.T CTRP2 4.7596 6.7217 4.6537 16.7975
G-402 CTRP2 4.951 7.2712 4.7313 15.9296
Rh18 CTRP2 5.1236 6.9986 4.9899 14.4741
RD CTRP2 5.2477 8.123 4.7704 14.9178
BT-12 CTRP2 5.2686 6.0172 5.2664 13.0539
RKN CTRP2; CTRP1 5.4168 6.7942 5.3507 12.2859
MES-SA CTRP2 6.3041 6.9297 6.2828 6.227
Tm87-16 CTRP2 6.3686 7.2555 6.2827 6.0265
SK-LMS-1 CTRP2 6.3797 9.314 5.4152 9.4283
HT-1080 CTRP2; CTRP1 6.3846 7.392 6.2583 6.0679
BT-16 CTRP2 6.833 7.6481 6.6388 3.3644
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.9968 5.1779 3.9941 21.5204
COV434 CTRP2; CTRP1 3.738 5.0614 3.7344 23.246
OVK18 CTRP2; CTRP1 4.0044 6.2176 3.9256 21.7281
OC 314 CTRP2 4.1326 4.9617 4.1324 20.6081
OVCAR-4 CTRP2; CTRP1 4.2184 6.651 4.0812 20.507
OVKATE CTRP1 4.2759 5.7502 4.2591 42.0059
RMG-I CTRP2; CTRP1 4.6433 6.4869 4.5696 17.4589
MCAS CTRP2 4.8716 6.6265 4.7922 15.9601
OVCAR-8 CTRP2; CTRP1 4.893 6.5549 4.827 15.7712
A2780 CTRP2; CTRP1 4.9268 6.3161 4.8945 15.4305
ONCO-DG-1 CTRP2 5.1391 6.7202 5.0643 14.1639
HEY A8 CTRP2; CTRP1 5.1421 6.486 5.1031 14.0205
OVSAHO CTRP2 5.2068 7.49 4.9457 14.3813
OAW28 CTRP2 5.2386 7.2427 5.053 13.8954
RMUG-S CTRP1 5.2794 7.407 5.0461 29.2654
DOV13 CTRP2 5.2927 6.7145 5.2308 13.0974
SNU-8 CTRP2 5.2988 6.5134 5.2661 12.9561
JHOC-5 CTRP2; CTRP1 5.312 6.7269 5.2496 12.9705
JHOM-1 CTRP2; CTRP1 5.3767 7.4683 5.1374 13.1735
SNU-119 CTRP2 5.4188 7.4923 5.1757 12.9081
TYK-nu CTRP2; CTRP1 5.4295 7.3878 5.2196 12.7154
IGROV-1 CTRP2; CTRP1 5.4558 7.3271 5.2662 12.4669
Caov-3 CTRP2; CTRP1 5.4735 6.6363 5.4365 11.8083
TOV-112D CTRP2 5.4858 9.4821 4.4503 15.523
EFO-27 CTRP2; CTRP1 5.5122 7.4095 5.3031 12.1631
JHOS-4 CTRP1 5.5437 7.0298 4.5606 4.6015
Kuramochi CTRP2 5.6373 8.0123 5.2292 12.0781
SNU-840 CTRP2; CTRP1 5.9542 7.3879 5.7913 9.0593
ES2 CTRP2 5.9924 7.2519 5.8731 8.647
OVTOKO CTRP2 6.0235 7.8508 5.7035 9.1891
COV644 CTRP2; CTRP1 6.0256 7.441 5.8522 8.6241
OV-90 CTRP2; CTRP1 6.0858 7.07 6.0209 7.8313
JHOS-2 CTRP2 6.1163 9.559 5.0434 11.5732
COV362 CTRP2; CTRP1 6.2005 7.6713 5.9609 7.7123
COV318 CTRP1 6.2811 7.6565 4.7214 1.4841
OVISE CTRP2 6.3674 7.5878 6.171 6.4447
OVMANA CTRP1 6.4635 8.0509 4.6477 1.6752
OV7 CTRP2; CTRP1 6.5025 8.2537 6.0323 6.6264
OAW42 CTRP2; CTRP1 6.5212 7.1057 6.4864 4.8293
OVCAR-5 CTRP2 6.6654 8.1224 6.2556 5.3211
OV56 CTRP2 6.6937 7.2804 6.63 3.786
EFO-21 CTRP2; CTRP1 6.7838 8.3081 6.2848 4.9147
TOV-21G CTRP2 6.9651 10.1243 4.8404 4.7685
SK-OV-3 CTRP2; CTRP1 7.0562 9.2025 6.0947 5.1062
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.9301 7.6627 6.7311 2.7481
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 3.5969 6.789 3.3761 24.9321
NCI-H2452 CTRP2 4.3607 5.7002 4.3497 19.1263
NCI-H28 CTRP2; CTRP1 4.7126 7.141 4.5062 17.4661
NCI-H2052 CTRP2; CTRP1 5.1973 6.177 5.188 13.5521
ACC-MESO-1 CTRP2 5.7089 7.1325 5.5953 10.5108
IST-Mes1 CTRP2 6.2236 8.6404 5.5759 9.1587
MPP 89 CTRP2 6.5657 8.083 6.1732 5.903
JL-1 CTRP2 9.2804 15.5654 4.6215 7.5192
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 3.787 5.6721 3.7565 23.0101
PaCa-3 CTRP2; CTRP1 4.3044 6.2348 4.2436 19.6701
22Rv1 CTRP2 4.8758 6.945 4.7324 16.1563
VCaP CTRP2 5.7331 7.6593 5.4615 10.9285
DU145 CTRP2 6.3738 7.7573 6.1125 6.6501
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 4.9383 6.9326 4.8033 15.7108
YD-15 CTRP2 5.9126 6.9471 5.8583 8.9461
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 CTRP2 2.485 4.688 2.4675 31.6316
HGC-27 CTRP2 3.6626 4.5666 3.6625 23.7362
Hs 746.T CTRP2 3.7364 4.1867 3.7364 23.2443
SNU-16 CTRP2 3.7742 5.3143 3.7641 23.0266
HuG1-N CTRP2 4.0299 17.4262 -0.7313 34.703
KE-39 CTRP2 4.0325 6.2737 3.9473 21.5635
NCC-StC-K140 CTRP2 4.3587 6.0118 4.3263 19.2117
GSS CTRP2 4.5707 5.4009 4.57 17.6939
SNU-216 CTRP2 4.8356 7.6278 4.4982 17.1254
SNU-1 CTRP2 4.9627 6.4413 4.9178 15.2347
NCI-N87 CTRP2 5.0267 6.3748 4.9937 14.7678
Fu97 CTRP2; CTRP1 5.0311 6.4258 4.9925 14.7577
NUGC-3 CTRP2 5.0811 6.729 5 14.5717
MKN74 CTRP2; CTRP1 5.1755 6.9763 5.0515 14.0945
AGS CTRP2; CTRP1 5.2238 6.8808 5.1249 13.6848
MKN7 CTRP2; CTRP1 5.335 6.8334 5.255 12.879
KATO III CTRP2 5.4817 9.7692 4.3165 16.062
SNU-719 CTRP2 5.545 7.37 5.3508 11.891
23132/87 CTRP2 5.5806 6.8123 5.5242 11.1625
SNU-5 CTRP2 5.7019 8.3484 5.1641 12.1505
NUGC-4 CTRP2; CTRP1 5.8036 7.1734 5.6882 9.8874
SNU-601 CTRP2 5.8997 7.5908 5.6655 9.6849
ECC12 CTRP2 5.9846 7.6995 5.7186 9.2415
SNU-620 CTRP2 6.0605 7.4706 5.8805 8.4169
IM95 CTRP2 6.0678 9.2149 5.1566 11.2334
LMSU CTRP2 6.1419 7.8267 5.8389 8.3414
GSU CTRP2 6.142 6.6154 6.1393 7.2425
SNU-668 CTRP2 6.1577 7.5411 5.9619 7.8312
MKN1 CTRP2 6.1641 7.1689 6.0827 7.3693
SH-10-TC CTRP2; CTRP1 6.7704 7.6525 6.5722 3.7912
MKN45 CTRP2 7.4843 10.0819 6.0092 4.6498
SNG-M CTRP2; CTRP1 5.6107 7.2146 5.4668 11.2723
SNU-685 CTRP2 6.4399 9.9699 5.1558 10.3545
SNU-1077 CTRP2 6.7202 11.4093 4.7009 11.623
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-238 CTRP2 3.8332 4.4276 3.8332 22.6004
ML-1 [Human leukemia] CTRP2 4.3573 7.3251 4.0683 20.1241
8505C CTRP2 5.0903 7.4372 4.8349 15.1339
8305C CTRP2 5.3758 7.8353 5.0137 13.6352
B-CPAP CTRP2 5.4523 6.708 5.4034 11.9904
CAL-62 CTRP2 5.8394 7.4383 5.6505 9.9169
CGTH-W-1 CTRP2 6.1309 7.2927 6.0126 7.7233
SW579 CTRP2 6.2895 7.3223 6.1767 6.6498
FTC-133 CTRP2 6.4095 7.5291 6.2379 6.0721
TT CTRP2 6.4178 21.1051 -0.3963 28.606
BHT-101 CTRP2 6.4352 8.3025 5.9422 7.1573
TT2609-C02 CTRP2 6.926 8.64 6.2574 4.7034
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-4 CTRP2 3.7475 4.8264 3.7467 23.1733
HSC-2 CTRP2; CTRP1 4.636 5.7747 4.6291 17.2801
SCC-25 CTRP2 4.9175 7.1647 4.7237 16.0589
YD-8 CTRP2 5.0853 6.7838 4.9943 14.5784
SNU-1214 CTRP2 5.1025 7.2567 4.9007 14.8583
BICR 56 CTRP2 5.1853 6.5542 5.1401 13.7541
YD-10B CTRP2 5.3992 6.677 5.3512 12.3402
HSC-4 CTRP2 5.4252 6.3029 5.4166 12.0333
HSC-3 CTRP2 5.434 6.5191 5.4086 12.0313
PE/CA-PJ34 (clone C12) CTRP2 5.438 8.3885 4.8695 14.0093
SNU-46 CTRP2 5.4561 23.8166 -2.5851 34.4016
BICR 6 CTRP2 5.5241 6.6169 5.4928 11.4517
BHY CTRP2 5.6289 7.1695 5.4986 11.1026
PE/CA-PJ49 CTRP2 5.6843 7.158 5.5621 10.7051
SNU-1076 CTRP2 5.7513 6.8572 5.7005 10.0072
CAL-27 CTRP2 5.7851 6.8827 5.7324 9.7891
SNU-1041 CTRP2 5.9226 7.2889 5.7865 9.1716
PE/CA-PJ41 (clone D2) CTRP2 6.1036 7.864 5.7835 8.66
SNU-899 CTRP2 6.1263 8.3631 5.5999 9.3138
BICR 22 CTRP2 6.1829 7.4751 6.0118 7.572
CAL-33 CTRP2 6.2136 8.7517 5.5152 9.4272
FaDu CTRP2 6.2781 7.5935 6.0729 7.0687
Detroit 562 CTRP2 6.2949 7.5217 6.1169 6.855
SCC-9 CTRP2; CTRP1 6.472 7.2216 6.4048 5.2719
SNU-1066 CTRP2 6.478 10.2583 5.0504 10.7039
PE/CA-PJ15 CTRP2 6.5021 7.8835 6.1951 5.9821
BICR 16 CTRP2 6.5257 9.3563 5.5343 8.5985
BICR 31 CTRP2 6.6629 7.9221 6.3439 4.9742
BICR 18 CTRP2 6.7869 7.4973 6.6537 3.43
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2 3.7664 23.2735 -9.2651 28.974
U-BLC1 CTRP2 4.3757 6.3957 4.2967 19.258
JMSU-1 CTRP2 4.4587 5.2736 4.4583 18.4382
5637 CTRP2; CTRP1 4.8002 6.3677 4.7543 16.3192
KMBC-2 CTRP2; CTRP1 4.8857 6.1429 4.867 15.6577
RT-4 CTRP2; CTRP1 5.0275 6.1413 5.0145 14.6951
UM-UC-3 CTRP2; CTRP1 5.3984 6.7171 5.3441 12.3676
TCCSUP CTRP2 5.4698 7.3783 5.2663 12.4244
253J-BV CTRP2 5.5474 8.0013 5.1373 12.6804
647V CTRP2 5.5603 7.3474 5.3742 11.7597
SW1710 CTRP2 5.6128 7.7181 5.311 11.8388
VM-CUB-1 CTRP2 5.7073 7.3724 5.527 10.7622
SCaBER CTRP2 5.8689 7.0692 5.785 9.3413
CAL-29 CTRP2 5.9522 6.9744 5.8959 8.6899
253J CTRP2 5.9717 7.2492 5.8512 8.7886
UM-UC-1 CTRP2 5.9838 10.4426 4.4948 14.116
639V CTRP2 6.0817 7.1967 5.9856 7.9697
BFTC-905 CTRP2 6.1577 6.9872 6.1159 7.2718
RT-112 CTRP2 6.3396 7.2785 6.2444 6.253
HT-1376 CTRP2; CTRP1 6.3717 9.986 5.0839 10.8064
KU-19-19 CTRP2 6.4289 7.5072 6.2666 5.9086
T24 CTRP2 6.643 7.9729 6.3009 5.1964
BC-3C CTRP2 6.6606 7.6154 6.4727 4.4741
J82 CTRP2 8.3824 14.3622 4.5719 9.0731
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 6.5435 7.1434 6.5024 4.7032

References

1 Novel agents in the management of Mycobacterium tuberculosis disease. Curr Med Chem. 2007;14(18):2000-8.
2 Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro. J Cell Mol Med. 2010 Apr;14(4):982-91.
3 Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells. Cancer Res. 2007 Feb 1;67(3):1262-9. doi: 10.1158/0008-5472.CAN-06-1794.
4 Exposure to dietary fatty acids oleic and palmitic acid alters structure and mechanotransduction of intestinal cells in vitro. Arch Toxicol. 2023 Jun;97(6):1659-1675. doi: 10.1007/s00204-023-03495-3. Epub 2023 Apr 29.