Details of the Drug

General Information of Drug (ID: DM6PBUM)

Drug Name
Birinapant
Synonyms
Birinapant; 1260251-31-7; Birinapant (TL32711); TL-32711; UNII-6O4Z07B57R; TL 32711; 6O4Z07B57R; (2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methyl]-1H-indol-2-yl]-1H-indol-3-yl]methyl]-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl]-2-(methylamino)propanamide
Indication
Disease Entry ICD 11 Status REF
Lymphoma 2A80-2A86 Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 1/2 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 3 Molecular Weight (mw) 806.9
Logarithm of the Partition Coefficient (xlogp) 3.3
Rotatable Bond Count (rotbonds) 15
Hydrogen Bond Donor Count (hbonddonor) 8
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C42H56F2N8O6
IUPAC Name
(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methyl]-1H-indol-2-yl]-1H-indol-3-yl]methyl]-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl]-2-(methylamino)propanamide
Canonical SMILES
CC[C@@H](C(=O)N1C[C@H](C[C@H]1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)C[C@@H]6C[C@@H](CN6C(=O)[C@H](CC)NC(=O)[C@H](C)NC)O)O)NC(=O)[C@H](C)NC
InChI
InChI=1S/C42H56F2N8O6/c1-7-33(49-39(55)21(3)45-5)41(57)51-19-27(53)15-25(51)17-31-29-11-9-23(43)13-35(29)47-37(31)38-32(30-12-10-24(44)14-36(30)48-38)18-26-16-28(54)20-52(26)42(58)34(8-2)50-40(56)22(4)46-6/h9-14,21-22,25-28,33-34,45-48,53-54H,7-8,15-20H2,1-6H3,(H,49,55)(H,50,56)/t21-,22-,25-,26-,27-,28-,33-,34-/m0/s1
InChIKey
PKWRMUKBEYJEIX-DXXQBUJASA-N
Cross-matching ID
PubChem CID
49836020
CAS Number
1260251-31-7
UNII
6O4Z07B57R
DrugBank ID
DB11782
TTD ID
D0E8NP
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cellular inhibitor of apoptosis 1 (BIRC2) TTQ5LRD BIRC2_HUMAN Modulator [3]
X-linked inhibitor of apoptosis protein (XIAP) TTR7B60 XIAP_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 142 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 4.7581 14.0411 0.9293 23.0469
MEC1 CTRP2 7.2562 8.6996 5.539 0.6424
JM1 CTRP2 6.1769 7.3797 5.4837 2.113
WSU-DLCL2 CTRP2 -8.6643 -6.7495 -8.6643 94.8851
NB4 CTRP2 -5.9825 -5.1737 -5.9825 80.1244
M-07e CTRP2 -4.7928 -1.9509 -4.7934 71.8656
SR CTRP2 -4.4953 -1.653 -4.496 69.9517
SUP-M2 CTRP2 -4.4865 4.1077 -4.9833 64.6677
Ki-JK CTRP2 -4.0851 0.4446 -4.1152 66.3546
ALL-SIL CTRP2 -2.9303 0.6695 -2.9439 59.5654
RCH-ACV CTRP2 -2.1506 10.2644 -4.3235 52.6688
MOLM-16 CTRP2 -2.0848 29.6906 -13.0872 51.0551
Karpas-299 CTRP2 -1.1483 1.5523 -1.1553 47.928
MHH-CALL-4 CTRP2 -0.2818 10.2342 -2.3275 44.8702
MOLM-13 CTRP2 -0.1182 4.1078 -0.2684 41.438
SEM CTRP2 0.4273 6.0203 -0.0791 38.7741
MOLT-13 CTRP2 1.5491 12.6525 -1.4817 37.5753
EoL-1 CTRP2 1.8996 9.1638 0.4065 32.3354
PL21 CTRP2 1.9163 9.3124 0.3623 32.4031
ME1 CTRP2 2.5647 5.5803 2.3628 23.8776
DND-41 CTRP2 2.5692 11.8692 -0.1026 31.6443
NCO2 CTRP2 3.3505 12.3302 0.4477 27.9935
NCI-H929 CTRP2 3.419 9.4394 1.8588 23.2203
Kasumi-1 CTRP2 3.5131 11.8274 0.8442 26.3753
MV4-11 CTRP2 3.6178 11.0745 1.3024 24.6221
MOLT-16 CTRP2 3.8408 12.8087 0.687 26.0124
RPMI-8226 CTRP2 3.8889 9.1123 2.4814 19.6617
MOTN-1 CTRP2 4.1292 13.9461 0.4025 26.1432
KCL-22 CTRP2 4.3404 11.2534 1.9122 20.661
MOLM-6 CTRP2 4.363 12.2525 1.4478 22.2543
NOMO-1 CTRP2 4.9305 12.2466 1.9723 19.0563
L-428 CTRP2 5.0115 11.3346 2.4959 16.8882
Daudi CTRP2 5.0949 7.3514 4.495 8.6117
MM1.S CTRP2 5.154 9.7021 3.4292 12.8264
SKM-1 CTRP2 5.164 11.0562 2.7716 15.4642
OCI-Ly10 CTRP2 5.2727 8.0987 4.3199 8.8896
Karpas-422 CTRP2 5.3138 6.6406 5.0313 5.9176
Peer CTRP2 5.422 12.0698 2.4985 15.9783
P31/FUJ CTRP2 5.4857 9.6611 3.7517 10.7661
MOLP-2 CTRP2 5.4944 13.4729 1.8624 18.2229
GDM-1 CTRP2 5.5508 11.4964 2.8969 14.1306
RL CTRP2 5.554 6.134 5.4824 3.5218
Hs 611.T CTRP2 5.5579 6.3697 5.3993 3.8258
Granta-519 CTRP2 5.5621 6.3733 5.4023 3.8025
GA-10 CTRP2 5.6108 6.8026 5.2628 4.2306
L-363 CTRP2 5.6425 9.1401 4.15 8.7729
KE-37 CTRP2 5.6462 16.8086 0.327 22.9568
KMS-21-BM CTRP2 5.6934 12.6169 2.4612 15.5533
Ku812 CTRP2 5.7171 16.5424 0.5202 22.2339
BV-173 CTRP2 5.8364 9.4984 4.1412 8.4089
KM-H2 CTRP2 5.8582 12.0704 2.8749 13.5871
RPMI-8402 CTRP2 5.8769 8.4855 4.6816 6.0599
HH [Human lymphoma] CTRP2 5.897 7.5205 5.1802 3.9273
TALL-1 [Human adult T-ALL] CTRP2 5.9731 8.8827 4.5654 6.3559
HuNS1 CTRP2 6.0201 7.155 5.4687 2.4673
NALM-6 CTRP2 6.1178 13.1179 2.5686 14.2831
DB CTRP2 6.1437 7.4449 5.4251 2.4179
SUP-B15 CTRP2 6.1576 10.0516 4.1344 7.8103
EJM CTRP2 6.3216 8.4103 5.0838 3.5334
HL-60 CTRP2 6.3255 7.8191 5.379 2.2989
RPMI-6666 CTRP2 6.3613 7.6149 5.505 1.7239
HT CTRP2 6.3731 11.1194 3.7753 8.9101
SU-DHL-1 CTRP2 6.3839 9.0708 4.804 4.5941
OCI-Ly19 CTRP2 6.4087 8.0074 5.3474 2.2968
SK-MM-2 CTRP2 6.4538 9.7748 4.5084 5.7078
KYO-1 CTRP2 6.4911 9.7043 4.572 5.3783
RS4;11 CTRP2 6.4915 10.443 4.2057 6.9053
LP-1 CTRP2 6.6001 8.0975 5.4359 1.6631
697 CTRP2 6.6744 10.6562 4.2402 6.4492
KO52 CTRP2 6.7667 8.6487 5.2838 2.042
MC116 CTRP2 6.809 8.3758 5.4375 1.3982
JJN-3 CTRP2 6.8215 9.3191 5.0007 3.0946
Raji CTRP2 6.8284 8.4511 5.4147 1.4615
OCI-Ly3 CTRP2 6.8456 8.1866 5.5443 0.9689
L-540 CTRP2 6.8484 10.9283 4.2358 6.1818
MOLT-3 CTRP2 6.8574 8.161 5.5622 0.8947
F-36P CTRP2 6.971 9.8771 4.8344 3.551
OCI-AML-3 CTRP2 6.9768 8.3574 5.5414 0.8556
HEL CTRP2 6.9918 9.3732 5.0878 2.5177
U266B1 CTRP2 7.0088 9.0467 5.2505 1.8705
HPB-ALL CTRP2 7.0146 9.7887 4.9059 3.2047
U-937 CTRP2 7.018 10.3254 4.6509 4.2231
JVM-3 CTRP2 7.0767 12.1141 3.821 7.5183
DEL CTRP2 7.0768 8.2039 5.6557 0.4286
SIG-M5 CTRP2 7.0995 8.2028 5.6666 0.3859
OCI-AML-2 CTRP2 7.1567 10.9567 4.4421 4.866
KMS-27 CTRP2 7.1623 8.8503 5.4271 1.0735
NU-DUL-1 CTRP2 7.1685 8.8195 5.4438 1.0119
SU-DHL-10 CTRP2 7.2379 8.1693 5.7381 0.1642
Mino CTRP2 7.4366 8.6563 5.6375 0.2895
SUP-T11 CTRP2 7.4433 9.6737 5.2203 1.5202
CMK CTRP2 7.446 8.5753 5.6716 0.217
EM-2 CTRP2 7.4677 9.7319 5.2081 1.539
HEL 92.1.7 CTRP2 7.4857 8.4634 5.7273 0.114
KMS-12-BM CTRP2 7.522 8.9578 5.5583 0.4986
CML-T1 CTRP2 7.5245 15.9924 2.2436 12.9834
KMS-20 CTRP2 7.5363 14.2102 3.1282 9.5728
AMO1 CTRP2 7.547 8.6505 5.6838 0.1639
OCI-M1 CTRP2 7.5519 8.7424 5.6523 0.2168
OCI-AML-5 CTRP2 7.5527 8.6034 5.7028 0.1331
KHM-1B CTRP2 7.5693 10.8106 4.7804 2.9904
HDLM-2 CTRP2 7.5724 12.8021 3.8386 6.6894
NU-DHL-1 CTRP2 7.6103 15.666 2.468 12.003
KMS-26 CTRP2 7.652 8.5993 5.7404 0.0682
P12-Ichikawa CTRP2 7.6647 14.1157 3.2664 8.8282
SET-2 CTRP2 7.6781 8.76 5.6942 0.1167
A4/Fukuda CTRP2 7.68 9.2406 5.5174 0.4509
BL-70 CTRP2 7.7135 8.6933 5.73 0.0695
AML-193 CTRP2 7.7172 13.9257 3.3958 8.2374
TF-1 CTRP2 7.7223 8.842 5.6818 0.1239
K-562 CTRP2 7.7523 9.3392 5.5106 0.4322
THP-1 CTRP2 7.753 14.6963 3.0465 9.5555
KMS-11 CTRP2 7.7612 12.0603 4.3185 4.5303
Kasumi-2 CTRP2 7.7951 16.2131 2.335 12.2013
KE-97 CTRP2 7.7965 13.5446 3.635 7.175
SU-DHL-4 CTRP2 7.841 9.5173 5.4802 0.4607
Jurkat CTRP2 7.8415 11.2066 4.7626 2.7496
KMS-34 CTRP2 7.8457 8.8415 5.726 0.0562
LAMA-84 CTRP2 7.8553 12.9138 3.9763 5.7456
P3HR-1 CTRP2 7.8897 10.4078 5.1409 1.3912
Karpas-620 CTRP2 7.9219 9.4893 5.5248 0.3301
PF-382 CTRP2 7.934 15.2653 2.8981 9.8531
A3/Kawakami CTRP2 7.9732 8.8313 5.7723 0.0186
JURL-MK1 CTRP2 7.9936 16.7414 2.2205 12.3071
SUP-T1 CTRP2 8.0194 9.421 5.588 0.188
SU-DHL-8 CTRP2 8.0663 9.4767 5.5859 0.1795
SU-DHL-6 CTRP2 8.1629 21.7476 -0.1192 19.593
EHEB CTRP2 8.2617 10.2178 5.3912 0.4721
SUP-HD1 CTRP2 8.2949 10.1638 5.4252 0.3883
KMS-18 CTRP2 8.3165 9.8659 5.5417 0.1837
REC-1 CTRP2 8.3185 10.095 5.4601 0.3141
Toledo CTRP2 8.3404 9.9119 5.5343 0.1885
Ri-1 CTRP2 8.356 11.4379 4.9433 1.6445
Ci-1 CTRP2 8.4146 17.8982 1.9579 12.5984
HD-MY-Z CTRP2 8.4285 9.8625 5.5836 0.1112
Namalwa CTRP2 8.4503 9.7131 5.6417 0.0578
Mono-Mac-6 CTRP2 8.6105 19.68 1.2289 14.7838
CA46 CTRP2 8.6994 10.2995 5.5302 0.125
HuT 78 CTRP2 9.0012 10.834 5.4543 0.1582
Mono-Mac-1 CTRP2 9.1199 11.8798 5.1206 0.6936
KMM-1 CTRP2 9.2592 11.4679 5.3273 0.2681
MHH-CALL-3 CTRP2 12.0955 36.041 -4.259 23.115
⏷ Show the Full List of 142 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 2.8793 9.2521 1.3891 26.3583
TE8 CTRP2 8.3985 9.6954 5.6298 0.0722
TE-4 CTRP2 -0.0194 34.6116 -13.5615 47.7575
OE21 CTRP2 6.0412 12.7064 2.7108 13.8755
KYSE-140 CTRP2 6.3041 24.2149 -2.8254 29.0236
TE-1 CTRP2 7.4163 9.5612 5.2548 1.4267
KYSE-410 CTRP2 7.4615 10.6483 4.789 3.0868
OE19 CTRP2 7.6086 8.9489 5.5985 0.3014
TE-14 CTRP2 7.7106 15.7136 2.5183 11.6507
KYSE-30 CTRP2 7.874 9.2377 5.5981 0.2114
TE-9 CTRP2 7.9063 9.6959 5.4395 0.5254
TE-10 CTRP2 7.9612 11.0403 4.9051 2.118
KYSE-450 CTRP2 8.0884 9.3247 5.647 0.0978
KYSE-70 CTRP2 8.2316 9.94 5.4825 0.3019
KYSE-520 CTRP2 8.2612 10.3417 5.3436 0.5795
EC-GI-10 CTRP2 8.304 10.1493 5.4342 0.3673
OE33 CTRP2 8.4777 15.6226 3.0999 8.2916
KYSE-510 CTRP2 8.5437 9.9279 5.6018 0.0787
TE-5 CTRP2 8.6531 10.2766 5.5215 0.1421
COLO 680N CTRP2 8.6949 17.3277 2.4297 10.4853
TE-11 CTRP2 10.0472 19.4152 2.3277 9.049
KYSE-150 CTRP2 12.1694 21.5142 2.6204 5.8276
KYSE-180 CTRP2 12.9085 25.3852 1.3184 9.0882
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 15.0705 30.3532 0.3328 9.7507
BxPC-3 CTRP2 -2.9596 1.7503 -3.0229 59.3571
TCC-Pan2 CTRP2 3.5243 11.1991 1.1523 25.3644
Panc 03.27 CTRP2 3.9055 15.2979 -0.4668 29.0262
HuP-T4 CTRP2 4.5517 10.0883 2.6749 17.2558
MIA PaCa-2 CTRP2 6.0239 7.3593 5.3698 2.8752
Panc 08.13 CTRP2 6.7972 14.0667 2.642 12.7257
SU.86.86 CTRP2 7.3326 10.2987 4.871 2.9296
Hs 766T CTRP2 7.5045 10.9945 4.6546 3.5513
Panc 10.05 CTRP2 7.5922 10.1981 5.0715 1.8956
SNU-213 CTRP2 7.7125 9.3049 5.5067 0.4605
Capan-1 CTRP2 7.771 17.0414 1.9101 13.7891
Panc 05.04 CTRP2 7.8215 12.005 4.3828 4.2049
QGP-1 CTRP2 7.8283 9.2544 5.574 0.2684
SUIT-2 CTRP2 7.8492 9.1987 5.6026 0.2111
KP-4 CTRP2 7.8587 9.1988 5.6062 0.2024
L3.3 CTRP2 7.874 9.151 5.6292 0.1628
YAPC CTRP2 7.8894 12.4124 4.2353 4.6897
Panc 02.03 CTRP2 7.9381 12.7878 4.09 5.1912
PaTu 8988t CTRP2 7.949 9.1277 5.6649 0.1012
HuP-T3 CTRP2 7.9742 13.4439 3.803 6.2647
PaTu 8988s CTRP2 8.0407 12.9884 4.0617 5.1689
CFPAC-1 CTRP2 8.0713 10.1027 5.3533 0.652
HPAC CTRP2 8.1283 9.6562 5.5452 0.2258
PaTu 8902 CTRP2 8.1608 9.4984 5.6131 0.1235
AsPC-1 CTRP2 8.3474 10.5893 5.2851 0.6766
KP-2 CTRP2 8.3487 9.6217 5.6374 0.0716
SNU-410 CTRP2 8.3902 15.0757 3.3023 7.6395
HPAF-II CTRP2 8.5273 11.0739 5.1749 0.8571
KP-3 CTRP2 8.6086 12.7727 4.5004 2.9014
PK-59 CTRP2 8.6323 15.5874 3.2189 7.6307
SW1990 CTRP2 8.673 10.2543 5.5363 0.1227
PSN1 CTRP2 8.7049 10.2794 5.539 0.1152
Capan-2 CTRP2 8.7646 11.0831 5.2737 0.5145
PK-45H CTRP2 8.7909 10.2306 5.5853 0.0655
Panc 04.03 CTRP2 8.8092 16.6954 2.8094 8.9275
DAN-G CTRP2 11.5934 44.9669 -9.0081 30.0837
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.0585 7.6596 5.2485 3.318
Hs 852.T CTRP2 -1.2395 225.3015 -109.7117 49.9464
A101D CTRP2 -0.569 6.5303 -1.3113 45.1297
Hs 940.T CTRP2 -0.045 13.3502 -3.4098 44.8478
COLO 741 CTRP2 0.4761 9.92 -1.4007 41.0074
Malme-3M CTRP2 0.564 11.0662 -1.7873 41.2316
Hs 944.T CTRP2 2.1999 15.8708 -2.3513 37.1127
A-375 CTRP2 4.2828 21.0354 -2.9655 33.1828
SK-MEL-1 CTRP2 5.1177 11.8618 2.3314 17.2861
SK-MEL-30 CTRP2 6.1633 11.175 3.5775 10.1223
HT-144 CTRP2 6.2594 7.5295 5.4725 2.0193
SK-MEL-28 CTRP2 6.6866 8.0114 5.5306 1.1896
Hs 294T CTRP2 6.851 14.6351 2.4013 13.5553
Hs 688(A).T CTRP2 6.8748 8.6765 5.3392 1.6928
WM793 CTRP2 6.9383 14.6912 2.4416 13.2464
Hs 839.T CTRP2 6.9654 9.8434 4.8468 3.5092
Hs 934.T CTRP2 7.0405 8.6173 5.4626 1.0651
HMCB CTRP2 7.1081 8.4465 5.5712 0.6525
RPMI-7951 CTRP2 7.3352 20.4231 -0.0996 20.948
LOX-IMVI CTRP2 7.3508 13.1127 3.531 8.2598
IGR-37 CTRP2 7.3608 9.1939 5.3842 1.0429
SK-MEL-5 CTRP2 7.411 13.362 3.4526 8.4803
WT2-iPS CTRP2 7.5373 8.7245 5.6531 0.2203
Mel JuSo CTRP2 7.5432 9.7062 5.2601 1.2942
MDA-MB-435S CTRP2 7.6316 10.6022 4.9129 2.4262
UACC-62 CTRP2 7.6541 8.7541 5.6874 0.1313
WM115 CTRP2 7.6724 12.3872 4.1056 5.4846
UACC-257 CTRP2 7.7271 8.9592 5.6419 0.1814
WM1799 CTRP2 7.7466 12.4506 4.1246 5.309
IGR-39 CTRP2 7.7605 9.2578 5.5451 0.3519
COLO 792 CTRP2 7.7743 12.8238 3.9654 5.8992
COLO 800 CTRP2 7.8245 10.0921 5.241 1.1275
K029AX CTRP2 7.8315 8.9799 5.6736 0.1121
Hs 936.T CTRP2 7.8972 8.8577 5.7383 0.0417
IPC-298 CTRP2 7.9504 9.2157 5.6348 0.1376
RVH-421 CTRP2 7.981 9.5325 5.5326 0.2936
SK-MEL-3 CTRP2 8.0672 9.1779 5.6894 0.061
Hs 895.T CTRP2 8.0748 9.1908 5.6877 0.0616
SK-MEL-31 CTRP2 8.1417 13.247 4.0049 5.2593
SK-MEL-24 CTRP2 8.314 9.5902 5.636 0.077
G-361 CTRP2 8.4192 14.6606 3.5183 6.7725
CJM [Human melanoma] CTRP2 8.6067 14.4229 3.7493 5.655
WM88 CTRP2 8.6355 10.0925 5.5781 0.0879
WM983B CTRP2 8.7339 10.5327 5.4618 0.2004
WM266-4 CTRP2 8.8439 16.573 2.8905 8.5795
COLO 829 CTRP2 8.8881 10.6617 5.473 0.1564
Mel Ho CTRP2 9.3636 19.6952 1.7479 11.94
SK-MEL-2 CTRP2 9.6196 26.3153 -1.2879 20.3612
IGR-1 CTRP2 10.1259 20.128 2.0441 9.9218
A2058 CTRP2 11.8895 27.6338 -0.354 14.953
MeWo CTRP2 12.6314 24.3536 1.6219 8.4612
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 8.5847 10.4162 5.4471 0.2575
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-DZ CTRP2 6.4349 7.7584 5.4869 1.6882
SK-N-AS CTRP2 6.7321 8.5136 5.3251 1.9254
IMR-32 CTRP2 6.9681 8.0771 5.6556 0.5003
Kelly CTRP2 7.429 8.8349 5.5651 0.4636
MHH-NB-11 CTRP2 7.4814 12.5692 3.8881 6.6245
NH-6 CTRP2 7.9466 9.5356 5.5175 0.3353
CHP-126 CTRP2 8.1916 9.6973 5.5546 0.1947
SK-N-FI CTRP2 8.1916 9.5374 5.6107 0.1208
CHP-212 CTRP2 8.2836 9.8301 5.542 0.1908
KP-N-SI9s CTRP2 8.3597 12.746 4.3699 3.6251
SK-N-BE(2) CTRP2 8.6231 10.2233 5.5291 0.1387
SiMa CTRP2 8.824 10.5734 5.4805 0.1592
SK-N-SH CTRP2 8.8591 10.4548 5.5335 0.0993
NB1 CTRP2 9.4178 15.5548 3.7194 4.84
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-28 CTRP2 5.6306 14.844 1.2952 19.9291
SNU-478 CTRP2 6.6492 15.2402 1.9403 15.6431
HuCC-T1 CTRP2 7.0464 11.3191 4.1883 6.0637
SNU-869 CTRP2 7.3068 11.2211 4.4176 4.7499
SNU-1079 CTRP2 7.888 10.0211 5.3014 0.9024
SNU-1196 CTRP2 8.1204 11.541 4.7726 2.426
SNU-308 CTRP2 12.0561 26.4212 0.3242 12.9012
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 5.9207 6.7693 5.5743 2.2284
SK-N-MC CTRP2 6.4422 7.8562 5.4448 1.8483
TC71 CTRP2 6.7862 8.4929 5.3693 1.6847
Hs 888.T CTRP2 6.8511 8.5613 5.3778 1.5742
CAL-78 CTRP2 7.1709 22.0569 -1.0435 23.7007
MHH-ES-1 CTRP2 7.2277 10.1696 4.8649 3.0849
Hs 822.T CTRP2 7.2293 8.1005 5.7597 0.1298
SaOS-2 CTRP2 7.3637 9.2294 5.3705 1.0851
SK-ES-1 CTRP2 7.6467 9.0601 5.5724 0.3411
SJSA-1 CTRP2 8.0962 9.9502 5.4232 0.4736
SW1353 CTRP2 8.137 10.6178 5.1766 1.0951
CADO-ES1 CTRP2 8.3163 9.8457 5.5487 0.174
MG-63 CTRP2 8.3423 10.145 5.4512 0.3224
HOS CTRP2 8.4895 9.9656 5.57 0.116
U2OS CTRP2 8.5208 10.6293 5.3436 0.4667
G-292 clone A141B1 CTRP2 8.8162 10.6436 5.4532 0.1943
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 71 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-231 CTRP2 -3.6928 7.527 -5.0211 59.2203
MDA-MB-157 CTRP2 -1.6146 31.2571 -13.4012 50.2519
BT-549 CTRP2 -0.9085 40.7329 -17.3877 49.281
Hs 578T CTRP2 0.6082 17.8053 -4.8113 43.8838
CAL-85-1 CTRP2 2.8792 15.6331 -1.5891 34.0433
MCF-7 CTRP2 3.1226 16.7703 -1.913 34.0256
HCC1143 CTRP2 3.6011 11.5574 1.0577 25.4692
BT-474 CTRP2 3.7257 8.4124 2.6262 19.5397
HDQ-P1 CTRP2 4.562 12.3938 1.563 21.3799
KPL-1 CTRP2 6.1065 11.0831 3.5766 10.2341
DU4475 CTRP2 6.3417 8.1764 5.2149 2.9531
CAMA-1 CTRP2 6.3872 33.8249 -7.5613 35.189
SK-BR-3 CTRP2 6.8307 9.5192 4.9106 3.4449
HMC-1-8 CTRP2 6.9414 10.5463 4.4901 4.9911
HCC1500 CTRP2 7.095 29.7201 -4.9297 31.0524
AU565 CTRP2 7.1467 9.7689 5.0011 2.6586
HCC1937 CTRP2 7.1992 10.9582 4.4705 4.6899
HCC1428 CTRP2 7.4335 8.7504 5.6001 0.3751
ZR-75-1 CTRP2 7.6109 9.2455 5.4848 0.5694
Hs 578Bst CTRP2 7.6222 9.1192 5.5393 0.4272
MDA-MB-453 CTRP2 7.6428 12.8112 3.8826 6.4122
CAL-148 CTRP2 7.7424 14.4744 3.147 9.1789
CAL-51 CTRP2 7.7673 9.8858 5.2986 0.9945
HCC1419 CTRP2 7.8559 8.9726 5.685 0.0946
CAL-120 CTRP2 7.8678 9.1404 5.6306 0.1622
MDA-MB-361 CTRP2 7.8801 9.8296 5.3751 0.7031
HCC38 CTRP2 7.9036 13.1553 3.8934 6.0058
HCC2218 CTRP2 8.0513 14.9648 3.1257 8.7994
BT-20 CTRP2 8.1481 9.5762 5.5813 0.1668
HCC1954 CTRP2 8.1631 13.1068 4.0841 4.9284
JIMT-1 CTRP2 8.2439 9.543 5.6275 0.0943
ZR-75-30 CTRP2 8.3775 9.8825 5.5584 0.1488
HCC1806 CTRP2 8.4216 10.2721 5.436 0.324
HCC202 CTRP2 8.6857 10.6425 5.4044 0.2981
T-47D CTRP2 8.9486 10.9739 5.386 0.2575
MDA-MB-468 CTRP2 9.2644 18.5278 2.2393 10.373
HCC1395 CTRP2 10.335 23.6498 0.5097 14.5331
BT 216 CTRP2 3.1428 11.295 0.7323 27.7145
BT 187 CTRP2 3.9616 15.065 -0.3008 28.4724
BT 145 CTRP2 6.3604 8.665 4.9872 3.87
BT 286 CTRP2 6.8211 10.4936 4.4292 5.4283
BT 271 CTRP2 7.0331 9.6599 4.9793 2.8896
BT 504 CTRP2 7.0629 8.6263 5.4709 1.0158
BT 428 CTRP2 7.065 12.9498 3.401 9.2454
BT164 CTRP2 7.0765 8.4459 5.5556 0.7255
BT 482 CTRP2 7.148 8.7778 5.4509 1.0065
BT 440 CTRP2 7.2114 9.9265 4.9683 2.7044
BT 320 CTRP2 7.2424 8.2489 5.7104 0.2154
BT 498 CTRP2 7.2869 8.9528 5.4486 0.8965
BT 231 CTRP2 7.3998 13.5352 3.3597 8.8695
BT 359 CTRP2 7.4015 8.8411 5.5502 0.518
BT 139 CTRP2 7.4214 13.6676 3.3106 9.0314
BT 159 CTRP2 7.4695 9.1958 5.4382 0.7906
BT 333 CTRP2 7.5457 8.8003 5.6284 0.265
BT 330 CTRP2 7.5851 9.0686 5.5428 0.4372
BT 172 CTRP2 7.5871 10.0063 5.1533 1.6151
BT 245 CTRP2 7.6409 9.735 5.2985 1.0899
BT 248 CTRP2 7.6759 11.524 4.5156 3.8743
BT147 CTRP2 7.7134 11.3013 4.6424 3.3432
BT 444 CTRP2 7.7209 9.1298 5.5769 0.3017
BT 416 CTRP2 7.7789 8.9351 5.67 0.1274
BT 340 CTRP2 8.0036 9.2922 5.6276 0.136
BT 228 CTRP2 8.0182 9.4935 5.5615 0.2305
BT 179 CTRP2 8.0294 9.1179 5.6965 0.0595
BT 239 CTRP2 8.0443 9.1189 5.7013 0.0541
BT 112 CTRP2 8.0602 9.0784 5.7202 0.0396
BT 232 CTRP2 8.0949 9.5956 5.5542 0.2206
BT 224 CTRP2 8.1982 9.2661 5.7046 0.0383
BT 131 CTRP2 8.5203 21.9905 0.0289 18.5981
BT 422 CTRP2 8.5615 16.8179 2.5836 10.1114
BT 328 CTRP2 11.7003 24.6594 0.9221 11.5848
⏷ Show the Full List of 71 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 10.2385 20.5444 1.9207 10.1964
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-60 CTRP2 -3.0994 2.6915 -3.2586 59.6552
SNU-626 CTRP2 -2.5834 1.3113 -2.6104 57.2518
8-MG-BA CTRP2 -2.1927 11.5693 -4.8844 52.6139
GMS-10 CTRP2 0.7627 4.1163 0.6697 35.4846
SNU-466 CTRP2 4.9579 11.7152 2.2594 17.9184
KALS-1 CTRP2 5.5464 21.5665 -2.1355 29.1351
M059K CTRP2 6.3475 7.2979 5.6487 1.1613
KNS-81 CTRP2 6.5451 8.4782 5.2153 2.6289
SF295 CTRP2 6.6666 8.4753 5.3002 2.1115
LN-229 CTRP2 7.0289 8.9402 5.3114 1.6197
LN-18 CTRP2 7.3363 8.2258 5.7556 0.1087
DK-MG CTRP2 7.4717 11.602 4.3462 4.8058
CAS-1 CTRP2 7.5421 15.6284 2.4361 12.235
YKG-1 CTRP2 7.5607 9.1451 5.5019 0.5534
KG-1-C CTRP2 7.5957 8.6848 5.6901 0.1414
GaMG CTRP2 7.5986 10.8989 4.7577 3.0422
42-MG-BA CTRP2 7.6009 9.5525 5.3549 0.946
NMC-G1 CTRP2 7.6388 8.924 5.6201 0.2472
GOS-3 CTRP2 7.7614 11.6726 4.5001 3.8284
SNU-1105 CTRP2 7.7729 9.1252 5.5995 0.2401
CCF-STTG1 CTRP2 7.7877 9.0584 5.6295 0.1846
A-172 CTRP2 7.8084 9.4095 5.5076 0.4132
TM-31 CTRP2 7.8241 9.0403 5.6498 0.1451
U-87MG ATCC CTRP2 7.8474 9.5043 5.4879 0.4401
SNU-489 CTRP2 7.934 9.0077 5.7006 0.0674
SNU-738 CTRP2 8.145 9.3233 5.6674 0.0704
ONS-76 CTRP2 8.1709 9.6944 5.5478 0.2102
U-251MG CTRP2 8.2628 9.526 5.6398 0.08
D283 Med CTRP2 8.2828 9.6534 5.6034 0.1133
SW1088 CTRP2 8.3749 9.9193 5.5445 0.167
DBTRG-05MG CTRP2 8.4293 9.9957 5.5378 0.1645
GB-1 CTRP2 8.4622 10.1309 5.5024 0.2055
SF126 CTRP2 8.4622 9.8105 5.6131 0.0787
SF268 CTRP2 8.4683 10.4369 5.3939 0.3862
Hs 683 CTRP2 8.4842 16.4362 2.7143 9.7366
T98G CTRP2 8.6377 10.1288 5.5666 0.0979
Becker CTRP2 8.8394 10.2313 5.6015 0.0509
SNB-75 CTRP2 8.8898 11.0903 5.3214 0.3784
U-118MG CTRP2 10.017 22.9928 0.6088 14.6728
Daoy CTRP2 10.1235 18.903 2.6129 7.9678
SNU-201 CTRP2 11.2978 24.5811 0.7032 12.719
SF539 CTRP2 12.2753 26.0863 0.6176 11.8136
KNS-42 CTRP2 12.8368 27.3576 0.3759 11.8703
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-265 CTRP2 -6.7721 10.0291 -9.2027 65.597
ESS-1 CTRP2 -6.1033 -5.3838 -6.1033 80.9291
KLE CTRP2 -1.3174 11.622 -3.9849 49.4626
EN CTRP2 6.5334 7.7139 5.5735 1.2105
EFE-184 CTRP2 7.5437 9.5272 5.3367 1.0461
HEC-6 CTRP2 7.5788 9.4515 5.386 0.8683
HEC-108 CTRP2 7.821 9.0498 5.6452 0.1523
AN3-CA CTRP2 7.8274 11.7765 4.4929 3.7756
JHUEM-1 CTRP2 8.0355 8.9114 5.7667 0.0179
JHUEM-3 CTRP2 8.0396 9.9374 5.4039 0.5446
HEC-251 CTRP2 8.0532 9.4819 5.5791 0.1929
MFE-319 CTRP2 8.1488 10.0793 5.3962 0.5107
RL95-2 CTRP2 8.1737 9.7657 5.5233 0.249
JHUEM-7 CTRP2 8.3084 9.7317 5.5856 0.129
HEC-1-B CTRP2 8.4388 10.1916 5.4719 0.2578
JHUEM-2 CTRP2 8.5683 10.1924 5.52 0.1594
HEC-59 CTRP2 8.5761 9.9863 5.5933 0.082
HEC-1-A CTRP2 8.7066 10.4186 5.4916 0.1677
MFE-296 CTRP2 8.8264 18.6299 1.8923 12.2122
HEC-50B CTRP2 8.8639 16.6692 2.8581 8.6728
HEC-151 CTRP2 11.0046 20.5089 2.4084 7.6666
Ishikawa (Heraklio) 02 ER- CTRP2 7.6185 8.6406 5.7141 0.1034
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR10TKB CTRP2 -0.7293 2.8296 -0.778 45.2244
BFTC-909 CTRP2 6.3934 8.0156 5.3324 2.3828
SNU-1272 CTRP2 6.8559 23.5687 -2.051 26.5286
TUHR4TKB CTRP2 7.2541 8.8397 5.4797 0.8245
RCC10RGB CTRP2 7.546 9.2261 5.4626 0.6688
Caki-2 CTRP2 7.7986 9.0087 5.6513 0.1488
786-O CTRP2 7.9523 9.7399 5.4424 0.496
OS-RC-2 CTRP2 8.0384 9.8175 5.4494 0.4411
KMRC-3 CTRP2 8.0821 16.2255 2.5359 11.0015
VMRC-RCW CTRP2 8.0874 10.0128 5.3954 0.5413
KMRC-2 CTRP2 8.1161 9.5185 5.5897 0.1624
769-P CTRP2 8.1407 9.5367 5.5924 0.1534
KMRC-20 CTRP2 8.1967 9.7379 5.5421 0.2124
ACHN CTRP2 8.2139 9.8164 5.5205 0.242
KMRC-1 CTRP2 8.564 9.7819 5.6573 0.039
UO-31 CTRP2 8.5662 10.4405 5.4312 0.2882
A-498 CTRP2 8.586 19.4032 1.3464 14.4338
TUHR14TKB CTRP2 8.619 10.7213 5.3493 0.4183
VMRC-RCZ CTRP2 8.72 10.0663 5.6158 0.0515
CAL-54 CTRP2 8.7355 10.2678 5.5537 0.097
Caki-1 CTRP2 9.0105 10.6044 5.5355 0.0803
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 CTRP2 -3.5976 9.5134 -5.5944 57.8755
SNU-C2A CTRP2 -0.1538 8.6705 -1.5828 43.6473
LS180 CTRP2 1.6938 10.8491 -0.527 35.2857
SNU-1033 CTRP2 2.6201 10.288 0.6677 29.3887
LoVo CTRP2 4.2001 8.2308 3.1927 16.0884
LS123 CTRP2 4.2986 11.6662 1.6727 21.6244
OUMS-23 CTRP2 5.6372 6.3077 5.5081 3.188
HT115 CTRP2 6.323 8.4019 5.089 3.5092
HCC-56 CTRP2 6.4932 7.819 5.4975 1.5632
T84 CTRP2 6.4938 9.0356 4.9048 3.9896
HT-55 CTRP2 7.0777 10.2157 4.7444 3.7623
SW620 CTRP2 7.1676 9.3035 5.2284 1.7731
DLD-1 CTRP2 7.2315 8.3285 5.6757 0.2952
SNU-C5 CTRP2 7.2825 17.1576 1.4829 16.118
SW948 CTRP2 7.2943 8.6243 5.5876 0.4815
LS411N CTRP2 7.353 8.8051 5.5422 0.5694
LS513 CTRP2 7.4444 8.8875 5.5513 0.4906
SNU-407 CTRP2 7.4677 15.2376 2.5733 11.8377
NCI-H747 CTRP2 7.5028 10.7509 4.767 3.1209
LS1034 CTRP2 7.5258 9.1841 5.47 0.6609
RCM-1 [Human ESC] CTRP2 7.5937 9.2406 5.4788 0.5952
COLO201 CTRP2 7.7085 10.451 5.0247 1.9455
SNU-C4 CTRP2 7.7534 8.8177 5.7016 0.0934
NCI-H508 CTRP2 7.7596 20.7955 0.045 19.8047
COLO205 CTRP2 7.7806 8.9561 5.6632 0.1363
SNU-503 CTRP2 7.7861 9.241 5.562 0.307
HT-29 CTRP2 7.7958 8.8985 5.6889 0.1005
C2BBe1 CTRP2 7.9393 10.11 5.2896 0.902
HCT 15 CTRP2 7.9528 9.1719 5.651 0.1167
CL-11 CTRP2 8.1248 10.5738 5.1888 1.068
HCT 116 CTRP2 8.1624 9.6222 5.5703 0.1789
HCT 8 CTRP2 8.1743 9.2739 5.694 0.0469
MDST8 CTRP2 8.1876 9.5009 5.6218 0.1089
SW48 CTRP2 8.1994 9.8892 5.4883 0.3018
SK-CO-1 CTRP2 8.223 9.7083 5.5625 0.176
KM12 CTRP2 8.2495 9.7643 5.5526 0.1837
GP2d CTRP2 8.3319 9.7132 5.6004 0.1087
SNU-61 CTRP2 8.3684 10.0096 5.5102 0.2169
SNU-C1 CTRP2 8.4254 10.1007 5.4993 0.2189
SW1417 CTRP2 8.4846 10.1107 5.5179 0.179
NCI-H716 CTRP2 8.5357 10.1764 5.5137 0.1738
COLO 678 CTRP2 8.6962 10.4251 5.4856 0.1773
CCK-81 CTRP2 8.8379 10.4286 5.535 0.1007
COLO 320 CTRP2 9.4319 11.6467 5.3283 0.2292
RKO CTRP2 12.3912 28.1573 -0.276 14.1468
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLF CTRP2 5.8168 23.2238 -2.7357 29.7532
SNU-886 CTRP2 6.1002 13.0812 1.8684 12.0656
SNU-387 CTRP2 6.1968 12.4452 2.9701 12.54
Li-7 CTRP2 6.647 13.9093 2.6022 13.1521
PLC/PRF/5 CTRP2 6.7888 15.4213 1.961 15.3097
SNU-182 CTRP2 7.0122 9.564 5.011 2.7923
JHH-6 CTRP2 7.3936 8.3379 5.7373 0.1214
JHH-1 CTRP2 7.5377 10.4212 4.9397 2.4305
SNU-423 CTRP2 7.6974 10.9539 4.7922 2.7993
JHH-2 CTRP2 7.7694 9.3511 5.5134 0.4179
JHH-5 CTRP2 7.7806 12.1603 4.284 4.6398
SNU-475 CTRP2 7.7919 9.3568 5.5207 0.3914
Hep-G2 CTRP2 7.8115 9.2554 5.5669 0.2878
HuH-1 CTRP2 7.9354 9.2101 5.6312 0.1457
Hep 3B2.1-7 CTRP2 7.9593 9.6109 5.4945 0.3775
SNU-398 CTRP2 8.3461 14.3958 3.5958 6.5709
SNU-449 CTRP2 8.659 11.8515 4.9218 1.4815
JHH-4 CTRP2 11.485 24.4768 0.8717 11.9904
SK-HEP-1 CTRP2 14.1359 28.1411 0.7883 9.3979
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 139 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EPLC-272H CTRP2 -4.9764 8.8648 -6.8562 62.279
NCI-H2110 CTRP2 -2.7075 2.8543 -2.8622 57.4636
NCI-H1703 CTRP2 -2.5712 4.5588 -2.9981 56.0465
Sq-1 CTRP2 -1.5721 3.4451 -1.7292 50.6889
NCI-H1734 CTRP2 -1.2873 3.2817 -1.4063 48.906
SK-LU-1 CTRP2 -1.2072 6.7509 -2.0732 48.6893
HCC44 CTRP2 -0.6275 16.3262 -5.3424 47.497
SW1271 CTRP2 -0.3141 10.9395 -2.6502 45.2403
NCI-H1975 CTRP2 1.4361 9.4864 -0.2133 35.4211
NCI-H2085 CTRP2 1.464 9.8607 -0.3398 35.6166
HCC1833 CTRP2 1.4987 9.4265 -0.1229 35.0003
NCI-H196 CTRP2 1.7186 7.8491 0.7317 31.9963
NCI-H211 CTRP2 2.2031 18.0006 -3.3742 38.4953
NCI-H1755 CTRP2 2.2251 9.5499 0.584 30.8168
LCLC-97TM1 CTRP2 2.9253 16.8455 -2.134 34.9007
NCI-H2228 CTRP2 3.3423 8.1947 2.3204 21.7401
NCI-H2030 CTRP2 3.846 11.316 1.4095 23.6692
MOR/CPR CTRP2 4.0522 16.4724 -0.9106 29.7332
RERF-LC-Ad1 CTRP2 4.2386 11.0615 1.908 20.9251
NCI-H23 CTRP2 4.2554 15.3991 -0.1964 27.4978
NCI-H1568 CTRP2 4.2981 11.8618 1.5773 21.9618
NCI-H1793 CTRP2 5.0631 11.666 2.3791 17.2245
NCI-H647 CTRP2 5.2199 9.5426 3.5683 12.1072
IA-LM CTRP2 5.8777 6.702 5.5681 2.3489
NCI-H1693 CTRP2 6.0437 9.8716 4.1302 8.0452
DMS 53 CTRP2 6.119 7.4548 5.4004 2.5663
NCI-H146 CTRP2 6.194 7.6388 5.3681 2.5667
SK-MES-1 CTRP2 6.4114 10.0242 4.3515 6.4372
DV-90 CTRP2 6.4165 9.3711 4.68 5.0558
EBC-1 CTRP2 6.5537 15.9641 1.5024 17.3799
NCI-H358 CTRP2 6.6594 14.1589 2.4876 13.5726
NCI-H650 CTRP2 6.673 23.4575 -2.144 27.0456
COR-L95 CTRP2 6.7452 9.0015 5.1013 2.7983
NCI-H446 CTRP2 6.7646 10.3173 4.4744 5.3317
NCI-H2087 CTRP2 6.7745 8.9661 5.1381 2.6095
NCI-H810 CTRP2 6.7779 8.0496 5.567 0.9565
EKVX CTRP2 6.8197 10.218 4.5632 4.8793
CAL-12T CTRP2 6.8447 11.5762 3.9138 7.5153
HCC366 CTRP2 6.8513 13.6283 2.9021 11.6093
NCI-H2009 CTRP2 6.8597 20.4271 -0.4793 22.8333
NCI-H1435 CTRP2 6.8913 17.4715 1.0204 18.3691
NCI-H1341 CTRP2 6.946 8.6478 5.3952 1.402
NCI-H2196 CTRP2 6.9562 9.8009 4.861 3.4653
HCC2935 CTRP2 7.0181 16.9521 1.3792 16.9437
NCI-H1838 CTRP2 7.0302 12.2263 3.7316 7.9584
RERF-LC-A1 CTRP2 7.1516 10.2345 4.7847 3.5006
NCI-H889 CTRP2 7.1639 9.4239 5.1714 1.989
NCI-H1694 CTRP2 7.2167 8.8853 5.441 0.9794
NCI-H2444 CTRP2 7.2596 8.668 5.5537 0.6904
HOP-92 CTRP2 7.2662 10.1736 4.8875 2.9484
NCI-H1155 CTRP2 7.2761 11.7733 4.1301 5.9522
NCI-H1105 CTRP2 7.2774 9.3135 5.287 1.448
LK2 CTRP2 7.2937 8.1558 5.7644 0.1061
NCI-H526 CTRP2 7.3014 8.687 5.5657 0.5367
HCC1588 CTRP2 7.3025 9.1932 5.3536 1.195
BEN CTRP2 7.3307 8.253 5.7438 0.1276
NCI-H2141 CTRP2 7.3724 9.1846 5.3942 1.0011
HCC95 CTRP2 7.4115 9.5514 5.2565 1.4252
DMS 454 CTRP2 7.4549 20.6924 -0.1399 20.8499
SBC-5 CTRP2 7.5131 8.5415 5.7099 0.1324
NCI-H292 CTRP2 7.5211 9.5177 5.3292 1.0881
NCI-H1573 CTRP2 7.5369 9.4293 5.3745 0.9338
Calu-3 CTRP2 7.5804 9.5146 5.3605 0.9441
NCI-H226 CTRP2 7.5939 8.8977 5.6117 0.2802
LXF 289 CTRP2 7.6483 14.222 3.2029 9.1037
SHP-77 CTRP2 7.6548 9.0696 5.5722 0.3381
NCI-H2291 CTRP2 7.6865 13.1184 3.7647 6.8187
NCI-H522 CTRP2 7.7039 13.9579 3.3708 8.3562
NCI-H524 CTRP2 7.7247 9.2189 5.5449 0.3676
HCC1438 CTRP2 7.7341 9.1701 5.5672 0.3164
LOU-NH91 CTRP2 7.7425 9.1764 5.5683 0.3109
NCI-H1563 CTRP2 7.7438 9.1464 5.58 0.287
RERF-LC-Ad2 CTRP2 7.7545 10.1617 5.1757 1.3909
NCI-H2126 CTRP2 7.7581 13.7662 3.5015 7.7587
NCI-H1581 CTRP2 7.7603 9.2284 5.5561 0.3289
NCI-H2286 CTRP2 7.7853 9.591 5.4268 0.6216
T3M-10 CTRP2 7.8004 13.1472 3.8284 6.4045
NCI-H1184 CTRP2 7.8231 17.4464 1.7493 14.273
NCI-H69 CTRP2 7.8308 9.8955 5.3254 0.8716
NCI-H1339 CTRP2 7.8311 12.06 4.3633 4.2683
LC-1/sq-SF CTRP2 7.8348 8.9302 5.692 0.0903
NCI-H1355 CTRP2 7.8466 10.2235 5.1969 1.2477
Lu-65 CTRP2 7.8481 9.3712 5.5387 0.3303
COR-L51 CTRP2 7.8728 9.4779 5.5087 0.3829
NCI-H1623 CTRP2 7.9041 9.9992 5.3179 0.8448
DMS 114 CTRP2 7.9285 9.409 5.5571 0.2659
NCI-H2122 CTRP2 7.9357 11.1566 4.8393 2.3742
NCI-H1915 CTRP2 7.9661 13.9434 3.5589 7.2328
NCI-H1385 CTRP2 7.9968 10.9268 4.9742 1.8483
NCI-H727 CTRP2 7.9995 10.6339 5.1013 1.4284
NCI-H322 CTRP2 8.0086 9.9288 5.3936 0.5848
COLO 699 CTRP2 8.0134 15.478 2.8508 9.9142
NCI-H460 CTRP2 8.0599 9.2265 5.6704 0.0786
NCI-H838 CTRP2 8.0831 9.699 5.512 0.2972
KNS-62 CTRP2 8.0831 9.1998 5.6875 0.0608
PC-14 CTRP2 8.0887 17.969 1.6881 14.0554
HOP-62 CTRP2 8.0994 9.6929 5.5207 0.2761
NCI-H2106 CTRP2 8.1005 10.0808 5.3748 0.584
NCI-H2081 CTRP2 8.1089 9.8864 5.4527 0.4044
NCI-H1792 CTRP2 8.113 9.9204 5.4416 0.4263
HCC1195 CTRP2 8.1223 13.6975 3.7801 6.1545
NCI-H1666 CTRP2 8.1472 18.8839 1.2817 15.3417
Calu-1 CTRP2 8.1477 9.8341 5.488 0.3199
NCI-H441 CTRP2 8.1809 9.8321 5.5019 0.2835
LCLC-103H CTRP2 8.1915 12.1207 4.5542 3.1341
DMS 273 CTRP2 8.2655 9.8082 5.543 0.1937
NCI-H2029 CTRP2 8.3072 18.1825 1.7423 13.5212
LUDLU-1 CTRP2 8.3509 10.2429 5.4185 0.381
Lu-99 CTRP2 8.3678 9.4747 5.6927 0.0332
NCI-H2170 CTRP2 8.3942 9.9699 5.5339 0.1771
HARA [Human squamous cell lung carcinoma] CTRP2 8.4553 10.2672 5.451 0.2875
NCI-H520 CTRP2 8.4572 10.1898 5.4795 0.2408
HCC4006 CTRP2 8.4927 10.4603 5.3951 0.3754
NCI-H2023 CTRP2 8.5321 12.9801 4.3648 3.4591
HCC2108 CTRP2 8.5554 10.5423 5.3899 0.3637
NCI-H2342 CTRP2 8.5596 10.012 5.5789 0.0969
VMRC-LCD CTRP2 8.5812 9.9404 5.6105 0.0677
COLO 668 CTRP2 8.6051 10.2085 5.5278 0.1433
NCI-H1299 CTRP2 8.6077 11.1215 5.1921 0.7708
HCC827 CTRP2 8.6434 10.281 5.5165 0.1496
NCI-H2172 CTRP2 8.6687 15.7802 3.1514 7.8371
HCC15 CTRP2 8.6831 10.5946 5.4207 0.2727
ChaGo-K-1 CTRP2 8.7005 10.2998 5.5305 0.1245
NCI-H2405 CTRP2 8.7108 10.6101 5.4257 0.2576
NCI-H661 CTRP2 8.7143 10.6947 5.3967 0.3027
NCI-H1395 CTRP2 8.7462 10.7684 5.3824 0.3172
A-549 CTRP2 8.8013 11.007 5.3169 0.4159
NCI-H1944 CTRP2 8.8034 10.4807 5.505 0.1352
HCC1171 CTRP2 8.8096 10.488 5.5048 0.1345
HCC2279 CTRP2 9.0537 16.8576 2.8929 8.2921
RERF-LC-MS CTRP2 9.1176 15.2436 3.6835 5.2984
COR-L105 CTRP2 9.437 11.5256 5.3722 0.176
NCI-H1869 CTRP2 9.4802 20.8021 1.2955 13.2794
NCI-H1373 CTRP2 9.4966 16.9477 3.1307 6.8712
NCI-H1650 CTRP2 10.4124 20.5781 2.0151 9.6646
HCC78 CTRP2 10.5415 20.9189 1.9374 9.7668
Calu-6 CTRP2 11.4015 26.3347 -0.0586 14.7618
NCI-H841 CTRP2 11.4903 23.2833 1.43 10.2787
Hs 888.Lu CTRP2 7.3505 9.1272 5.4073 0.9769
⏷ Show the Full List of 139 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.5308 15.2547 -0.7929 30.7268
SK-OV-3 CTRP2 -7.1258 2.5138 -7.5414 74.3909
OVCAR-4 CTRP2 -4.5638 1.9645 -4.7265 67.1689
Caov-3 CTRP2 0.6136 8.0871 -0.5433 39.0438
COV644 CTRP2 1.2723 10.0982 -0.6398 36.8985
A2780 CTRP2 4.4555 22.1576 -3.3718 33.4646
EFO-21 CTRP2 6.2009 12.6346 2.8788 12.8977
OVK18 CTRP2 6.3138 7.6052 5.4756 1.9185
OVCAR-8 CTRP2 6.4355 12.9352 2.9193 12.2927
TOV-21G CTRP2 6.5314 12.8191 3.0539 11.5766
JHOS-2 CTRP2 6.8399 15.3445 2.0395 14.929
COV434 CTRP2 6.8565 10.4348 4.4837 5.1484
TYK-nu CTRP2 7.0264 9.8825 4.8692 3.3349
HEY A8 CTRP2 7.2639 8.6597 5.5591 0.5792
COV362 CTRP2 7.2994 10.0229 4.9783 2.5595
OV7 CTRP2 7.3072 8.8279 5.511 0.6895
OV-90 CTRP2 7.3758 9.4284 5.2908 1.341
OAW42 CTRP2 7.3851 16.1195 2.0759 13.8361
OC 314 CTRP2 7.6454 11.8425 4.3464 4.572
ES2 CTRP2 7.7953 14.2911 3.2733 8.6033
ONCO-DG-1 CTRP2 7.8729 9.3441 5.5588 0.2817
DOV13 CTRP2 7.9214 9.4034 5.5563 0.2697
OVISE CTRP2 8.0063 9.1818 5.6668 0.0899
JHOM-1 CTRP2 8.0193 19.7011 0.784 17.1575
SNU-8 CTRP2 8.0614 9.332 5.6348 0.116
FU-OV-1 CTRP2 8.1071 9.7204 5.5137 0.2862
TOV-112D CTRP2 8.1377 9.672 5.5432 0.2265
SNU-119 CTRP2 8.3405 15.8801 2.8835 9.3068
OAW28 CTRP2 8.371 10.8327 5.1997 0.8816
EFO-27 CTRP2 8.4312 10.184 5.4717 0.2602
OVCAR-5 CTRP2 8.4594 10.0602 5.5263 0.1733
SNU-840 CTRP2 8.6199 10.2761 5.5097 0.1621
JHOC-5 CTRP2 8.6683 13.6211 4.155 4.0746
Kuramochi CTRP2 8.7529 17.1385 2.5599 9.9262
RMG-I CTRP2 8.7801 10.7028 5.4189 0.2503
MCAS CTRP2 8.8012 19.2098 1.5936 13.2767
OVTOKO CTRP2 8.806 10.7676 5.4055 0.2638
IGROV-1 CTRP2 8.9221 17.6703 2.4196 10.2003
OV56 CTRP2 9.0326 18.8577 1.9247 11.8005
OVSAHO CTRP2 11.0247 22.3737 1.5629 10.405
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 6.5943 8.5108 5.234 2.4801
Yamato-SS CTRP2 10.8832 29.7658 -2.0656 20.3862
KYM-1 CTRP2 -8.8908 -7.0537 -8.8908 95.8835
GCT CTRP2 -5.7934 -0.0731 -5.848 74.5556
A-204 CTRP2 -1.2493 1.8089 -1.264 48.6047
Tm87-16 CTRP2 -1.1976 6.3892 -1.9558 48.6057
SW982 CTRP2 2.188 7.6132 1.3231 28.6455
BT-12 CTRP2 4.3831 7.372 3.7526 13.4088
TE 617.T CTRP2 5.426 7.1332 4.9263 6.0476
Rh41 CTRP2 5.5266 10.776 3.2343 12.8138
TE 441.T CTRP2 5.6968 6.452 5.5089 3.0259
Hs 729.T CTRP2 6.2649 14.9569 1.7706 16.9883
RD CTRP2 6.4361 8.0214 5.3602 2.202
TTC-709 CTRP2 7.2582 12.8888 3.5735 8.2345
Rh18 CTRP2 7.3698 16.6652 1.7941 14.8785
HT-1080 CTRP2 7.4693 9.5643 5.2821 1.2859
BT-16 CTRP2 7.575 8.8012 5.6399 0.232
G-401 CTRP2 8.4402 15.274 3.2411 7.8054
SK-UT-1 CTRP2 8.7467 10.2431 5.566 0.085
SK-LMS-1 CTRP2 8.892 10.4623 5.5424 0.0878
G-402 CTRP2 9.4477 17.5591 2.8159 8.0688
RKN CTRP2 9.7385 22.8436 0.4886 15.4226
MES-SA CTRP2 13.6947 26.6852 1.1868 8.7002
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.9935 12.8867 3.3784 9.4558
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 7.4787 8.271 5.7911 0.0446
P-STS CTRP2 7.9786 9.4511 5.5615 0.2423
SYO-1 CTRP2 8.0506 18.8627 1.2207 15.7007
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP2 3.8175 19.1707 -2.4559 33.3443
IST-Mes1 CTRP2 6.4292 7.7424 5.4908 1.6809
ACC-MESO-1 CTRP2 6.9542 9.2344 5.1289 2.4058
MPP 89 CTRP2 6.9587 8.7902 5.3379 1.6
JL-1 CTRP2 7.2832 8.6439 5.5746 0.5235
NCI-H2452 CTRP2 8.2697 10.3211 5.3552 0.5487
MSTO-211H CTRP2 8.6159 10.7935 5.3211 0.4755
NCI-H2052 CTRP2 8.6855 10.4398 5.4765 0.1912
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP CTRP2 5.3775 6.4574 5.1733 5.1932
LNCaP clone FGC CTRP2 6.833 8.7775 5.2659 2.0265
NCI-H660 CTRP2 7.7953 8.8999 5.6883 0.1013
DU145 CTRP2 7.8232 10.1568 5.2131 1.2151
22Rv1 CTRP2 8.335 13.2545 4.1224 4.5745
PaCa-3 CTRP2 8.4294 14.7409 3.487 6.879
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 7.8735 8.7607 5.7623 0.0289
A-253 CTRP2 8.3531 9.7633 5.5908 0.1156
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUM-1 CTRP2 0.6238 20.6963 -6.1756 44.6161
GSS CTRP2 5.2646 8.7715 3.9867 10.2809
IM95 CTRP2 6.1196 10.1098 4.074 8.1353
SNU-620 CTRP2 6.5004 9.37 4.7447 4.6437
SNU-16 CTRP2 6.5566 7.8951 5.5032 1.4553
GSU CTRP2 6.9167 7.7711 5.7548 0.2612
SNU-5 CTRP2 6.9863 10.3526 4.6158 4.4119
ECC12 CTRP2 7.0827 10.9687 4.3847 5.2077
SNU-668 CTRP2 7.1819 9.3001 5.2384 1.7209
SNU-216 CTRP2 7.3057 9.495 5.2223 1.6491
SNU-601 CTRP2 7.3454 12.1569 3.9928 6.4044
NCI-N87 CTRP2 7.3634 9.3988 5.297 1.3313
KE-39 CTRP2 7.3697 18.4292 0.9188 17.8371
MKN45 CTRP2 7.373 8.4975 5.6709 0.2452
NUGC-4 CTRP2 7.5532 12.7018 3.8738 6.5768
MKN1 CTRP2 7.7158 14.476 3.1273 9.297
SH-10-TC CTRP2 7.8251 14.4776 3.2039 8.8309
ECC10 CTRP2 7.8738 9.3905 5.542 0.3138
Fu97 CTRP2 8.1774 15.2048 3.0968 8.7276
SNU-1 CTRP2 8.2209 10.1391 5.4039 0.4619
23132/87 CTRP2 8.2818 15.9371 2.8157 9.6488
HGC-27 CTRP2 8.3051 9.6038 5.6283 0.085
KATO III CTRP2 8.3248 11.1798 5.036 1.3807
MKN7 CTRP2 8.3818 10.1829 5.4529 0.3067
SNU-719 CTRP2 8.3909 10.5131 5.3333 0.5432
AGS CTRP2 8.4417 19.7734 1.0608 15.5942
Hs 746.T CTRP2 8.4549 24.773 -1.3947 22.3888
LMSU CTRP2 8.5342 9.9642 5.5862 0.0935
MKN74 CTRP2 9.0013 10.699 5.5005 0.1109
NUGC-3 CTRP2 9.2893 17.001 2.9765 7.684
SNU-685 CTRP2 7.1527 8.9963 5.3577 1.3223
SNU-1077 CTRP2 7.7514 9.9534 5.2624 1.1168
SNG-M CTRP2 10.9587 24.2585 0.6351 13.3446
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 5.7922 6.687 5.4946 2.8487
TT CTRP2 7.226 13.5403 3.2298 9.6679
FTC-133 CTRP2 7.2556 9.7595 5.0729 2.2531
BHT-101 CTRP2 7.6017 8.8263 5.6413 0.2204
B-CPAP CTRP2 7.6408 14.41 3.1059 9.497
CGTH-W-1 CTRP2 7.8365 9.4543 5.5024 0.4123
8505C CTRP2 8.0339 11.3802 4.7953 2.4316
CAL-62 CTRP2 8.0741 9.4664 5.5924 0.1681
ML-1 [Human leukemia] CTRP2 8.2217 9.7925 5.5321 0.2213
TT2609-C02 CTRP2 9.0901 10.7076 5.5283 0.0777
8305C CTRP2 9.1511 17.3147 2.7404 8.7235
FTC-238 CTRP2 11.5607 22.0463 2.0391 8.2725
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-3 CTRP2 -2.4431 0.618 -2.4494 56.4806
SCC-25 CTRP2 2.6174 11.4195 0.1526 30.8436
BICR 22 CTRP2 3.3408 12.5433 0.3368 28.3356
YD-10B CTRP2 5.3353 12.2355 2.3397 16.7778
BICR 31 CTRP2 6.51 7.9753 5.434 1.794
BICR 6 CTRP2 6.715 8.642 5.253 2.2329
CAL-27 CTRP2 6.7759 9.5468 4.859 3.7352
FaDu CTRP2 6.7815 8.5612 5.3345 1.8252
BICR 18 CTRP2 6.9853 10.5902 4.4999 4.8847
PE/CA-PJ34 (clone C12) CTRP2 7.1312 8.7049 5.4734 0.9459
YD-8 CTRP2 7.389 9.1941 5.3987 0.9731
HSC-4 CTRP2 7.5924 9.3649 5.4281 0.736
SCC-9 CTRP2 7.6797 9.4336 5.4413 0.6447
SNU-1076 CTRP2 7.6845 8.8009 5.6822 0.1316
SNU-1214 CTRP2 7.7882 14.086 3.3678 8.2422
CAL-33 CTRP2 7.8052 9.4549 5.4888 0.4578
SNU-46 CTRP2 7.8236 9.6595 5.417 0.6254
BICR 16 CTRP2 7.8763 9.8235 5.3758 0.7035
SCC-4 CTRP2 7.987 9.3791 5.5906 0.1923
SNU-1066 CTRP2 8.0438 10.1173 5.3352 0.7135
BICR 56 CTRP2 8.0525 9.4919 5.5752 0.1989
PE/CA-PJ41 (clone D2) CTRP2 8.4534 9.8488 5.5971 0.0942
SNU-1041 CTRP2 8.507 10.1022 5.5291 0.16
Detroit 562 CTRP2 8.5209 10.3828 5.4345 0.2958
HSC-2 CTRP2 9.4787 17.1519 3.025 7.2747
BHY CTRP2 9.565 26.2668 -1.3039 20.4794
PE/CA-PJ15 CTRP2 9.6447 18.358 2.5671 8.712
PE/CA-PJ49 CTRP2 9.6691 17.3999 3.0278 7.0378
SNU-899 CTRP2 9.9648 17.5472 3.1386 6.3066
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
647V CTRP2 -0.9564 4.6691 -1.269 46.9824
KMBC-2 CTRP2 0.5293 5.6412 0.1307 37.8675
SCaBER CTRP2 5.3066 12.5977 2.1343 17.6199
BFTC-905 CTRP2 6.089 7.048 5.5792 1.871
CAL-29 CTRP2 6.2754 8.3883 5.059 3.7172
JMSU-1 CTRP2 7.07 9.393 5.1281 2.2636
639V CTRP2 7.2651 9.8229 5.0496 2.3299
RT-4 CTRP2 7.4095 12.2475 3.9936 6.3059
U-BLC1 CTRP2 7.5786 14.6463 2.9454 10.2222
BC-3C CTRP2 7.7452 15.6979 2.5513 11.4707
J82 CTRP2 7.7739 14.1729 3.3157 8.4687
253J CTRP2 7.8439 8.9687 5.682 0.0999
5637 CTRP2 7.8563 15.4083 2.7731 10.4518
KU-19-19 CTRP2 7.9423 9.3535 5.5827 0.2172
T24 CTRP2 7.9432 10.4722 5.141 1.3475
253J-BV CTRP2 8.0637 9.4687 5.5877 0.1774
RT-112 CTRP2 8.2373 14.704 3.3776 7.5597
HT-1197 CTRP2 8.2427 9.7595 5.5518 0.4007
TCCSUP CTRP2 8.5323 9.9754 5.5818 0.098
SW1710 CTRP2 8.7244 10.4362 5.492 0.1638
UM-UC-3 CTRP2 9.3339 16.4745 3.2492 6.634
HT-1376 CTRP2 9.4276 20.0598 1.6164 12.2941
VM-CUB-1 CTRP2 12.0675 24.6017 1.1755 10.406
UM-UC-1 CTRP2 12.601 27.4766 0.1749 12.6886
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.2839 8.5727 5.6034 0.4458

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7432).
2 Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.Nat Rev Drug Discov. 2016 Aug;15(8):533-50.
3 cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner. Blood. 2014 Apr 17;123(16):2562-72.