Details of the Drug

General Information of Drug (ID: DM71BFM)

Drug Name
DNA-Ad
Synonyms DNA-prime/adenovirus (Ad5)-boost CSP-and AMA1-encoding malaria vaccine (Biojector2000, intramuscular), US NavalMedical Research Center (NMRC)/Bioject/Vical/GenVec
Indication
Disease Entry ICD 11 Status REF
Malaria 1F40-1F45 Phase 1/2 [1]
Drug Type
Vaccine
Cross-matching ID
TTD ID
D03KHQ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Plasmodium Apical membrane protein (Malaria AMA-1) TTQZW34 AMA1_PLAFF Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00870987) Clinical Trial for Malaria Vaccines to Test for Safety, Immune Response and Protection Against Malaria. U.S. National Institutes of Health.
2 Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+T cells targeting AMA1 class I epitopes. PLoS One. 2014 Sep 11;9(9):e106241.