Details of the Drug

General Information of Drug (ID: DM74YO8)

Drug Name
PDC-41
Synonyms
THG-113; THG-113.31; PDC-31 (iv, premature labor); PGF2 alpha antagonist (primary dysmenorrhea/topical), PDC Biotech; Prostaglandin F2 alpha antagonist (primary dysmenorrhea/topical), PDC Biotech; PDC-31 (iv, premature labor), PDC; PGF2 alpha antagonist (injectable, premature labor/dysmenorrhea), PDC Biotech; Prostaglandin F2 alpha antagonist (injectable, premature labor/dysmenorrhea), PDC Biotech
Indication
Disease Entry ICD 11 Status REF
Dysmenorrhea GA34.3 Phase 1 [1]
Cross-matching ID
TTD ID
D0TJ7S

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin F2-alpha receptor (PTGFR) TTT2ZAR PF2R_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Dysmenorrhea
ICD Disease Classification GA34.3
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Prostaglandin F2-alpha receptor (PTGFR) DTT PTGFR 8.25E-02 -0.05 -0.14
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01250587) Dose-Finding Study of PDC31 in Patients With Primary Dysmenorrhea. U.S. National Institutes of Health.
2 THG113: a novel selective FP antagonist that delays preterm labor. Semin Perinatol. 2002 Dec;26(6):389-97.