Details of the Drug

General Information of Drug (ID: DM756GE)

Drug Name
APH-0812
Synonyms Bryostatin-1 + HDAC inhibitor combination (HIV-1 infection), Aphios
Indication
Disease Entry ICD 11 Status REF
Human immunodeficiency virus-1 infection 1C62 Phase 2 [1]
Human immunodeficiency virus infection 1C62 Phase 1 [2]
Cross-matching ID
TTD ID
D08VAR

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase (HDAC) TTBH0VX NOUNIPROTAC Inhibitor [1]
Protein kinase C (PRKC) TTYVX59 NOUNIPROTAC Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Targeting the protein kinase C family: are we there yet. Nat Rev Cancer. 2007 Jul;7(7):554-62.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)