Details of the Drug

General Information of Drug (ID: DM79W8K)

Drug Name
ICo-007
Indication
Disease Entry ICD 11 Status REF
Diabetic macular edema 9B71.02 Phase 1 [1]
Diabetic retinopathy 9B71.0 Phase 1 [1]
Therapeutic Class
Antisense
Drug Type
Antisense drug
Cross-matching ID
DrugBank ID
DB05268
TTD ID
D0W2BK

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Raf messenger RNA (Raf mRNA) TTAN5W2 RAF1_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Diabetic macular edema
ICD Disease Classification 9B71.02
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Raf messenger RNA (Raf mRNA) DTT RAF1 2.12E-04 0.49 2.78
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
2 Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2009).