Details of the Drug

General Information of Drug (ID: DM7E324)

Drug Name
SAND-5
Synonyms Mubodina; Complement C5 minibody (hemolytic uremic syndrome/hemolytic uremic syndrome), ADIENNE
Indication
Disease Entry ICD 11 Status REF
Glomerulonephritis 5D00.Y Preclinical [1]
Cross-matching ID
DrugBank ID
DB17616
TTD ID
D0B1DA

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement C5 (CO5) TTKANGO CO5_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Glomerulonephritis
ICD Disease Classification 5D00.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement C5 (CO5) DTT C5 7.69E-01 -0.12 -0.23
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032848)
2 Progress and Trends in Complement Therapeutics. Adv Exp Med Biol. 2013; 734: 1-22.