General Information of Drug (ID: DM7ERXY)

Drug Name
Tominersen
Indication
Disease Entry ICD 11 Status REF
Huntington disease 8A01.10 Phase 3 [1]
Cross-matching ID
UNII
7QI41X9QWC
DrugBank ID
DB17924
TTD ID
DMOV12

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Huntingtin (HTT) TTUKLBM HD_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03761849) A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Patients With Manifest Huntington's Disease. U.S.National Institutes of Health.
2 Potential disease-modifying therapies for Huntington's disease: lessons learned and future opportunities. Lancet Neurol. 2022 Jul;21(7):645-658.