Details of the Drug

General Information of Drug (ID: DM7F3ZM)

• Drug Name: TS-071
• Synonyms: Luseogliflozin; 898537-18-3; UNII-C596HWF74Z; C596HWF74Z; CHEMBL1093423; Luseogliflozin [INN]; TS-071; TS-71; TS 071; Tube105; ts71; SCHEMBL1487519; DTXSID10237921; CHEBI:134725; ZINC49087932; BDBM50315426; AKOS027326750; SB11169; DB12214; (1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol; D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl]-, (1S); D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-(5-((4-ethoxyphenyl)methyl)-2-methoxy-4-methylphenyl)-, (1S)-

Indication

Disease Entry	ICD 11	Status	REF
Type-2 diabetes	5A11	NDA filed	[1]

• ATC Code:
  A10BK07: TS-071
  A10BK: Sodium-glucose co-transporter 2 (SGLT2) inhibitors
  A10B: BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
  A10: DRUGS USED IN DIABETES
  A: ALIMENTARY TRACT AND METABOLISM
• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C23H30O6S
  Canonical SMILES: CCOC1=CC=C(C=C1)CC2=CC(=C(C=C2C)OC)C3C(C(C(C(S3)CO)O)O)O
  InChI: InChI=1S/C23H30O6S/c1-4-29-16-7-5-14(6-8-16)10-15-11-17(18(28-3)9-13(15)2)23-22(27)21(26)20(25)19(12-24)30-23/h5-9,11,19-27H,4,10,12H2,1-3H3/t19-,20-,21+,22-,23+/m1/s1
  InChIKey: WHSOLWOTCHFFBK-ZQGJOIPISA-N
• Cross-matching ID:
  PubChem CID: 11988953
  ChEBI ID: CHEMBL1093423
  CAS Number: 898537-18-3
  UNII: C596HWF74Z
  DrugBank ID: DB12214
  TTD ID: D0IJ0U
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

References

• [1] Clinical pipeline report, company report or official report of Taisho Pharmaceutical.