Details of the Drug

General Information of Drug (ID: DM7GBDX)

Drug Name
N-Formylmethionine
Synonyms
N-formyl-L-methionine; 4289-98-9; for-met-oh; N-FORMYLMETHIONINE; (S)-2-Formamido-4-(methylthio)butanoic acid; Formyl-L-methionine; formylmethionine; L-Methionine, N-formyl-; UNII-PS9357B4XH; N-Formyl-L -Methionine; PS9357B4XH; PYUSHNKNPOHWEZ-YFKPBYRVSA-N; N-Formyl methionine; L-Formylmethionine; L-N-Formylmethionine; N-Formyl(methyl)homocysteine #; Formyl-methionine; N-formyl-l-met; 2-formamido-4-methylsulfanylbutanoic acid; NSC 334322; Methionine, N-formyl-; AC1L97YW; SCHEMBL38595; CHEBI:16552; CTK1D5830; MolPort-006-116-105
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 177.22
Logarithm of the Partition Coefficient (xlogp) 0.2
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C6H11NO3S
IUPAC Name
(2S)-2-formamido-4-methylsulfanylbutanoic acid
Canonical SMILES
CSCC[C@@H](C(=O)O)NC=O
InChI
InChI=1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
InChIKey
PYUSHNKNPOHWEZ-YFKPBYRVSA-N
Cross-matching ID
PubChem CID
439750
ChEBI ID
CHEMBL16552
CAS Number
4289-98-9
UNII
PS9357B4XH
DrugBank ID
DB04464
TTD ID
D0GV9Q

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Antithrombin-III (ATIII) TT4QPUL ANT3_HUMAN Inhibitor [1]
Glutamate--cysteine ligase modifier (GCLM) TTNFESW GSH0_HUMAN Inhibitor [1]
NADH dehydrogenase (MT-ND3) TTTJF7V NU3M_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.