Details of the Drug

General Information of Drug (ID: DM7L8SG)

Drug Name
AZD8055
Synonyms
AZD8055; 1009298-09-2; AZD-8055; AZD 8055; [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol; (5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol; UNII-970JJ37FPW; 970JJ37FPW; CHEMBL1801204; AK109550; (5-(2,4-Bis((S)-3-methylmorpholino)pyrido-[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol; (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 1/2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 465.5
Logarithm of the Partition Coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 9
Chemical Identifiers
Formula
C25H31N5O4
IUPAC Name
[5-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol
Canonical SMILES
C[C@H]1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOC[C@@H]5C
InChI
InChI=1S/C25H31N5O4/c1-16-14-33-10-8-29(16)24-20-5-6-21(18-4-7-22(32-3)19(12-18)13-31)26-23(20)27-25(28-24)30-9-11-34-15-17(30)2/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17-/m0/s1
InChIKey
KVLFRAWTRWDEDF-IRXDYDNUSA-N
Cross-matching ID
PubChem CID
25262965
ChEBI ID
CHEBI:91329
CAS Number
1009298-09-2
UNII
970JJ37FPW
DrugBank ID
DB12774
TTD ID
D0K1VK
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serine/threonine-protein kinase mTOR (mTOR) TTCJG29 MTOR_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [3]
Ribosomal protein S6 kinase beta-1 (RPS6KB1) OTAELNGX KS6B1_HUMAN Post-Translational Modifications [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serine/threonine-protein kinase mTOR (mTOR) DTT MTOR 2.16E-05 -0.44 -2.3
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 -0.0268 3.4416 -1.155 16.9004
SK-N-MC CTRP2 -10.7629 2.1814 -11.5177 79.5598
Hs 888.T CTRP2 -4.0568 29.9885 -15.1196 54.0996
RD-ES CTRP2 -3.0217 4.0171 -3.3791 58.5225
A-673 GDSC1; GDSC2; CTRP2 -2.2181 0.88 -2.2261 54.9943
SK-ES-1 GDSC1; GDSC2; CTRP2 -1.8324 2.8314 -1.9338 52.3355
TC71 CTRP2 -1.7929 6.4799 -2.6314 51.6818
ES8 GDSC1; GDSC2 -1.6925 1.8288 -2.2001 29.5962
EW-18 GDSC1; GDSC2 -1.6489 3.9418 -3.0083 32.9025
CHSA0108 GDSC1 -1.6466 4.0057 -3.034 39.1274
SJSA-1 GDSC1; GDSC2; CTRP2 -1.5325 5.0881 -2.1451 47.4894
ES7 GDSC1; GDSC2 -1.3959 2.7873 -2.2525 28.4653
ES1 GDSC1; GDSC2 -1.3775 1.9113 -1.8902 26.5558
ES5 GDSC1 -0.981 5.6833 -3.1447 35.7647
SK-PN-DW GDSC1; GDSC2 -0.9487 2.6902 -1.7442 23.8904
EW-22 GDSC1; GDSC2 -0.8361 4.2269 -2.317 26.3603
NOS-1 [Human HNSCC] GDSC1; GDSC2 -0.7978 3.0283 -1.7343 23.2043
MHH-ES-1 GDSC1; GDSC2; CTRP2 -0.7272 3.9604 -0.8986 45.4001
EW-16 GDSC1; GDSC2 -0.5773 3.4096 -1.6823 22.0261
EW-3 GDSC1; GDSC2 -0.5645 5.8237 -2.8138 27.5376
HuO-3N1 GDSC1; GDSC2 -0.5245 4.9171 -2.339 25.2252
TC-71 GDSC1; GDSC2 -0.5166 1.8881 -0.9605 17.6661
ES4 GDSC1; GDSC2 -0.451 3.49 -1.5934 21.035
CAL-72 GDSC1; GDSC2 -0.4304 3.7121 -1.6765 21.4178
EW-7 GDSC1; GDSC2 -0.3605 2.7414 -1.161 18.1991
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 -0.3064 7.2736 -1.2572 43.8993
HuO9 GDSC1; GDSC2 -0.1761 6.0764 -2.5744 25.0275
MG-63 GDSC1; GDSC2; CTRP2 -0.1476 11.7367 -2.812 44.7641
ES6 GDSC1; GDSC2 0.0981 4.1526 -1.3791 17.7724
CADO-ES1 GDSC1; GDSC2 0.2053 4.2422 -1.3232 17.0705
EW-11 GDSC1; GDSC2 0.3278 5.4006 -1.7829 19.2665
SW1353 CTRP2 0.3332 8.2697 -0.9116 40.7838
CHSA8926 GDSC1; GDSC2 0.4465 5.3599 -1.6568 18.1717
EW-1 GDSC1; GDSC2 0.656 2.8344 -0.2176 8.7708
EW-13 GDSC1; GDSC2 0.7145 4.7357 -1.1108 14.1259
H-EMC-SS GDSC1; GDSC2 0.8315 4.8731 -1.0787 13.5694
CHSA0011 GDSC1 0.9271 3.0737 -0.0982 8.9255
EW-24 GDSC1; GDSC2 1.0491 3.6984 -0.3085 8.1403
HOS GDSC1; GDSC2; CTRP2 1.4735 11.9927 -1.2595 37.4238
NY GDSC1; GDSC2 1.6016 5.7842 -0.9111 10.3857
U2OS GDSC1; GDSC2; CTRP2 2.2725 9.834 0.511 30.8804
CAL-78 GDSC1; GDSC2; CTRP2 2.9827 11.7178 0.3772 29.1941
SaOS-2 GDSC1; GDSC2; CTRP2 2.9911 12.2075 0.156 29.7811
Hs 822.T CTRP2 11.3542 28.5111 -1.131 17.6026
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -5.8133 4.7402 -6.5649 68.2273
JK1 CTRP2 -4.0592 13.597 -7.6779 57.4909
JM1 GDSC1; CTRP2 -0.8469 9.2377 -2.5384 47.2472
OCI-Ly10 CTRP2 -9.5078 8.4309 -11.8756 70.5708
Pfeiffer CTRP2 -8.9903 -0.583 -9.1809 81.8452
KMS-34 CTRP2 -8.1488 -6.8438 -8.1488 93.6655
BCP-1 CTRP2 -7.6792 -2.0557 -7.7031 83.4422
Hs 611.T CTRP2 -7.6597 6.5455 -9.2572 69.1706
OCI-Ly3 CTRP2 -7.5113 2.3209 -8.022 74.1249
SUP-T11 CTRP2 -7.3274 -3.3854 -7.3294 85.0596
EB1 CTRP2 -6.7543 12.347 -10.3642 62.8082
BL-70 CTRP2 -6.3989 -1.9644 -6.4074 79.6048
NCI-H929 GDSC1; GDSC2; CTRP2 -5.9959 -2.1483 -5.9995 78.2615
KMS-28BM CTRP2 -5.8379 3.0873 -6.252 70.2793
Kasumi-1 CTRP2 -5.3289 7.8366 -7.1454 62.4083
Ri-1 CTRP2 -5.2746 4.2557 -5.8699 67.1853
HuNS1 CTRP2 -5.1095 12.24 -8.2425 60.6033
SIG-M5 CTRP2 -4.7483 0.9725 -4.8295 69.0425
KMS-26 CTRP2 -4.5801 -1.3106 -4.5825 70.2827
Mino CTRP2 -4.4968 7.5637 -5.9077 61.8172
CRO-AP2 GDSC1 -4.4041 -0.1362 -4.6308 63.3444
KMS-18 CTRP2 -4.2667 0.8528 -4.3218 66.9394
MOLM-16 GDSC1; CTRP2 -4.0568 0.6814 -4.0963 66.0238
KMS-11 GDSC1; CTRP2 -3.9154 8.4019 -5.5494 59.4606
SU-DHL-4 GDSC1; CTRP2 -3.8515 3.1395 -4.1233 62.9805
SU-DHL-6 GDSC1; GDSC2; CTRP2 -3.8425 -0.4991 -3.8471 65.5396
EoL-1 GDSC1; GDSC2; CTRP2 -3.8268 -0.8593 -3.8306 63.1208
KMS-20 CTRP2 -3.8036 2.8359 -4.0273 63.0159
MV4-11 GDSC1; GDSC2; CTRP2 -3.7949 -0.0512 -3.8054 65.0528
GA-10 GDSC1; GDSC2; CTRP2 -3.7698 1.4567 -3.884 61.5147
Karpas-231 GDSC1; GDSC2 -3.6755 -1.3606 -3.7001 46.9739
KHM-1B CTRP2 -3.6452 0.7864 -3.678 63.7351
OCI-Ly7 GDSC1 -3.6354 -1.4231 -3.6553 57.6301
MM1.S GDSC1; GDSC2; CTRP2 -3.5865 -0.6789 -3.5883 64.0182
Farage GDSC1 -3.5533 -0.5931 -3.6421 56.2241
WSU-DLCL2 GDSC1; GDSC2; CTRP2 -3.5251 -0.101 -3.5318 63.464
Ki-JK CTRP2 -3.3989 -0.8347 -3.3997 62.8496
MY-M12 GDSC1 -3.3608 0.4374 -3.6181 53.6938
RCH-ACV GDSC1; CTRP2 -3.2896 2.7771 -3.4714 60.5846
MOLM-13 GDSC1; GDSC2; CTRP2 -3.2786 0.5832 -3.296 61.7176
BV-173 GDSC1; GDSC2; CTRP2 -3.2747 2.2362 -3.3939 60.8428
KMS-27 CTRP2 -3.2287 -0.3404 -3.231 61.6758
NU-DUL-1 GDSC1; CTRP2 -3.2045 -0.147 -3.2081 61.4829
YT GDSC1; GDSC2 -3.1936 0.2394 -3.3936 42.7334
SU-DHL-5 GDSC1; GDSC2 -3.1624 -1.3177 -3.1741 41.8203
NCO2 CTRP2 -3.0972 0.1453 -3.1033 60.7404
697 GDSC1; GDSC2; CTRP2 -3.0934 0.1284 -3.1047 57.9361
JURL-MK1 GDSC1; GDSC2; CTRP2 -3.084 0.6092 -3.0986 60.5301
Ramos.2G6.4C10 GDSC1; GDSC2 -3.0619 -0.4357 -3.1393 41.0707
M-07e CTRP2 -3.0489 9.5433 -5.0148 56.0568
Karpas-45 GDSC1; GDSC2 -3.0242 0.8003 -3.3388 41.4669
BDCM CTRP2 -2.9618 16.917 -7.9682 53.9177
OPM-2 GDSC1; GDSC2; CTRP2 -2.9569 -1.5015 -2.9569 57.1099
SU-DHL-10 GDSC1; GDSC2; CTRP2 -2.9298 -0.6476 -2.9302 59.7681
PL-21 GDSC1 -2.8446 1.1551 -3.239 48.4459
RPMI-8226 GDSC1; GDSC2; CTRP2 -2.8188 1.433 -2.8581 58.6522
WSU-NHL GDSC1 -2.8163 -0.3993 -2.8827 47.8217
KMS-12-BM GDSC2; CTRP2 -2.7891 3.9165 -3.1094 57.4215
JeKo-1 GDSC1; CTRP2 -2.7385 15.7721 -7.2341 53.5539
MOLP-8 GDSC1; GDSC2; CTRP2 -2.718 1.6253 -2.7645 57.9853
KMS-21-BM CTRP2 -2.6404 0.0606 -2.6425 57.819
CTB-1 GDSC1 -2.6279 0.9125 -2.9357 46.0713
HD-MY-Z CTRP2 -2.5053 8.0918 -3.9159 54.5243
HEL 92.1.7 CTRP2 -2.5008 5.9787 -3.2634 55.1815
Ku812 GDSC1; GDSC2; CTRP2 -2.4915 3.661 -2.7453 55.9703
A4/Fukuda GDSC1; GDSC2; CTRP2 -2.4765 5.2764 -3.0568 55.3121
RS4;11 GDSC1; GDSC2; CTRP2 -2.4038 4.1287 -2.8536 52.6137
Karpas-422 GDSC1; GDSC2; CTRP2 -2.3861 4.5306 -2.9304 52.4428
KE-37 GDSC1; GDSC2; CTRP2 -2.3676 2.7911 -2.4946 55.5567
Karpas-1106P GDSC1; GDSC2 -2.3604 1.3577 -2.7709 35.5669
L-363 GDSC1; GDSC2; CTRP2 -2.2965 0.3059 -2.2986 55.5469
PL21 CTRP2 -2.2959 8.0527 -3.6757 53.6794
Kasumi-2 CTRP2 -2.2865 9.2334 -4.0814 53.375
JVM-2 GDSC1; GDSC2; CTRP2 -2.254 4.3801 -2.6178 54.4652
SU-DHL-16 GDSC1 -2.2463 -1.1016 -2.2484 40.5913
HAL-01 GDSC1; GDSC2 -2.2176 1.6746 -2.7164 34.5774
SR GDSC1; GDSC2; CTRP2 -2.0942 2.5639 -2.1835 53.9792
OCI-AML-3 GDSC1; GDSC2; CTRP2 -2.0481 4.5589 -2.4305 53.3146
KCL-22 GDSC1; GDSC2; CTRP2 -2.0301 0.782 -2.0347 53.7712
SCC-3 GDSC2 -1.9892 1.6391 -2.4567 32.2673
AMO1 GDSC1; GDSC2; CTRP2 -1.9612 1.368 -1.9765 53.2871
NU-DHL-1 CTRP2 -1.9335 3.7412 -2.1587 52.8219
NKM-1 GDSC1; GDSC2 -1.8905 1.9257 -2.4482 31.7344
ATN-1 GDSC1; GDSC2 -1.8863 0.7811 -2.0929 30.009
GR-ST GDSC1; GDSC2 -1.8638 2.3414 -2.5721 32.1554
RPMI-6666 GDSC1; GDSC2; CTRP2 -1.7907 4.0158 -2.1614 48.9468
SUP-B15 GDSC1; GDSC2; CTRP2 -1.7623 5.6151 -2.362 51.6206
VAL GDSC1; GDSC2 -1.6872 2.6648 -2.5101 31.023
JSC-1 GDSC1; GDSC2 -1.6603 1.7809 -2.1487 29.1897
CTV-1 GDSC1; GDSC2 -1.6601 3.5455 -2.8475 32.3265
KYO-1 CTRP2 -1.6599 4.8009 -2.0596 51.1353
MHH-CALL-4 CTRP2 -1.6188 6.8645 -2.5562 50.7892
MHH-PREB-1 GDSC1; GDSC2 -1.6129 2.3245 -2.2976 29.6874
RL GDSC1; CTRP2 -1.6121 2.8485 -1.7035 50.9599
DB GDSC1; GDSC2; CTRP2 -1.6114 3.6859 -1.8049 50.9186
MOLP-2 CTRP2 -1.6102 10.2583 -3.7455 50.5987
P30/OHK GDSC1; GDSC2 -1.572 1.5362 -1.9698 27.87
NALM-6 GDSC1; GDSC2; CTRP2 -1.5633 3.9128 -1.7883 50.6192
HuT 78 CTRP2 -1.5539 13.6877 -5.1064 50.3067
OCI-Ly19 GDSC1; CTRP2 -1.5434 10.2134 -4.0041 48.2888
KE-97 CTRP2 -1.4984 4.1292 -1.7546 50.2258
JVM-3 GDSC1; GDSC2; CTRP2 -1.494 4.9062 -1.902 50.1905
SET-2 CTRP2 -1.4919 8.1124 -2.8252 50.1448
RPMI-8866 GDSC1; GDSC2 -1.4873 1.8918 -2.0013 27.6346
H9 GDSC1; GDSC2 -1.4722 3.111 -2.4674 29.8232
Reh GDSC1; GDSC2; CTRP2 -1.471 5.0139 -1.9007 50.0586
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 -1.4662 6.4845 -2.2765 50.0287
KMOE-2 GDSC1; GDSC2 -1.4527 1.4627 -1.816 26.5145
U-698-M GDSC1; GDSC2 -1.3916 2.4893 -2.1269 27.8288
Jiyoye GDSC1; GDSC2 -1.3712 1.7775 -1.8351 26.2387
LAMA-84 GDSC1; GDSC2; CTRP2 -1.3081 5.2592 -1.7796 49.1362
RPMI-8402 GDSC1; GDSC2; CTRP2 -1.2698 2.4408 -1.3137 48.7579
CMK GDSC1; CTRP2 -1.2274 1.668 -1.2498 44.8199
U-937 CTRP2 -1.1588 4.3692 -1.4308 48.1829
KOPN-8 GDSC1; GDSC2 -1.1453 2.9278 -2.0495 26.3412
Daudi GDSC1; GDSC2; CTRP2 -1.107 1.9082 -1.1219 47.6638
A3/Kawakami GDSC1; GDSC2 -1.0827 1.7051 -1.4981 23.1291
OCI-M1 GDSC1; GDSC2; CTRP2 -1.0632 4.0013 -1.2652 47.5493
EJM GDSC1; GDSC2; CTRP2 -1.0345 3.1062 -1.1786 43.7147
SUP-M2 GDSC1; GDSC2 -1.0198 0.2158 -1.0499 20.4219
HT GDSC1; CTRP2 -1.0045 2.9669 -1.0762 47.0557
NB4 GDSC1; CTRP2 -0.999 3.4544 -1.1207 47.0731
TF-1 CTRP2 -0.9751 10.2892 -3.0831 47.9812
MOTN-1 CTRP2 -0.957 29.3997 -11.8809 49.1104
Karpas-299 GDSC1; GDSC2; CTRP2 -0.946 5.0009 -1.327 46.9764
P32/ISH GDSC1; GDSC2 -0.885 2.476 -1.5878 22.7666
TK [Human B-cell lymphoma] GDSC1; GDSC2 -0.8793 3.3979 -1.9816 24.8582
TUR GDSC1; GDSC2 -0.8729 2.2947 -1.5005 22.2312
OCI-AML-2 GDSC1; GDSC2; CTRP2 -0.8666 6.2577 -1.5571 46.7567
QIMR-WIL GDSC1 -0.8409 2.5958 -1.592 27.8866
Granta-519 GDSC1; GDSC2; CTRP2 -0.8394 5.4607 -1.4951 43.3015
SUP-B8 GDSC1 -0.8196 6.546 -3.4047 35.787
KG-1 GDSC1; GDSC2 -0.8031 2.0159 -1.3152 20.8959
ST486 GDSC1; CTRP2 -0.7912 3.0956 -0.8639 45.6692
SU-DHL-8 GDSC1; GDSC2; CTRP2 -0.7737 3.8666 -0.9348 45.6821
MHH-CALL-2 GDSC1; GDSC2 -0.7674 2.452 -1.4548 21.5312
LP-1 GDSC1; CTRP2 -0.7535 2.0135 -0.7785 41.46
L-540 GDSC1; GDSC2; CTRP2 -0.75 4.704 -1.0522 45.7093
EM-2 GDSC1; GDSC2; CTRP2 -0.7356 7.418 -1.7708 46.3031
JJN-3 GDSC1; GDSC2; CTRP2 -0.7235 2.8628 -0.7744 45.1901
MOLT-4 GDSC1; GDSC2 -0.7215 3.0434 -1.663 22.5011
Sc-1 GDSC1 -0.6916 1.3384 -0.9484 22.849
Namalwa GDSC1; GDSC2; CTRP2 -0.6537 2.9571 -0.7531 40.9567
SK-MM-2 GDSC1; GDSC2; CTRP2 -0.644 4.5689 -1.0404 41.5756
MOLT-16 GDSC1; GDSC2; CTRP2 -0.6427 3.0518 -0.7045 44.6791
MOLM-6 CTRP2 -0.6387 16.3148 -5.3483 47.5304
THP-1 GDSC1; CTRP2 -0.6312 6.3054 -1.3138 45.4204
BC-1 GDSC1; GDSC2 -0.6057 2.0153 -1.1056 18.8714
CA46 GDSC1; GDSC2; CTRP2 -0.5682 2.8386 -0.6491 40.3044
F-36P CTRP2 -0.4719 7.9392 -1.6618 45.0505
DoHH2 GDSC1; CTRP2 -0.4396 4.0807 -0.6085 43.556
MJ CTRP2 -0.4335 18.8194 -6.3073 47.2388
L-1236 GDSC1; GDSC2; CTRP2 -0.3579 13.1807 -3.6549 46.0149
BE-13 GDSC1; GDSC2 -0.3159 3.2282 -1.338 19.0569
EB2 GDSC1; GDSC2 -0.3122 2.4633 -0.9882 16.995
ML-2 GDSC1; GDSC2 -0.292 5.8639 -2.5778 25.4676
RC-K8 GDSC1; GDSC2 -0.2581 2.6698 -1.025 16.9996
MEG-01 GDSC1; GDSC2 -0.1927 3.4159 -1.3042 18.3931
PF-382 GDSC1; GDSC2; CTRP2 -0.1719 6.2212 -0.7887 42.6558
SKM-1 GDSC1; CTRP2 -0.1496 3.1406 -0.1967 41.3959
ALL-PO GDSC1; GDSC2 -0.0633 3.7231 -1.3246 18.0339
Loucy GDSC1; GDSC2 -0.0489 2.6152 -0.7896 14.7936
Raji GDSC1; GDSC2; CTRP2 -0.0261 5.7945 -0.514 41.5484
SUP-HD1 GDSC1; GDSC2; CTRP2 0.0122 6.4931 -0.9016 38.4506
CML-T1 GDSC1; GDSC2; CTRP2 0.0358 4.5863 -0.1801 40.5904
P12-Ichikawa GDSC1; GDSC2; CTRP2 0.082 7.289 -0.8405 41.6675
DEL GDSC1; GDSC2; CTRP2 0.0891 4.0181 -0.0345 40.0187
KO52 CTRP2 0.1385 17.4349 -5.0964 45.287
VL51 GDSC1; GDSC2 0.1507 4.2788 -1.3917 17.6605
ROS-50 GDSC1 0.1819 4.6097 -1.525 22.3853
Ci-1 CTRP2 0.1859 22.8871 -7.6475 46.1892
HC-1 GDSC1; GDSC2 0.1912 5.9157 -2.1606 21.727
SUP-T1 GDSC1; GDSC2; CTRP2 0.2864 7.4149 -0.6608 40.5319
LC4-1 GDSC1; GDSC2 0.2967 4.5437 -1.3874 17.1327
L-428 GDSC1; GDSC2; CTRP2 0.3447 6.8379 -0.4093 39.818
DG-75 GDSC1; GDSC2 0.4376 3.8655 -0.9248 13.8893
HEL GDSC1; CTRP2 0.4526 4.7797 0.2348 37.8895
P31/FUJ GDSC1; GDSC2; CTRP2 0.4722 9.6943 -1.3133 40.8925
WIL2 NS GDSC1; GDSC2 0.531 2.1694 -0.0102 7.904
TALL-1 [Human adult T-ALL] CTRP2 0.5417 9.6026 -1.2029 40.4702
DND-41 GDSC1; GDSC2; CTRP2 0.562 6.8501 -0.1766 38.4722
Jurkat GDSC1; GDSC2; CTRP2 0.5621 4.6285 0.38 37.0742
K-562 GDSC1; GDSC2; CTRP2 0.5734 6.842 -0.1617 38.395
ARH-77 GDSC1; GDSC2 0.619 2.932 -0.2994 9.4047
BALL-1 GDSC1; GDSC2 0.6584 4.5587 -1.0715 14.065
HL-60 GDSC1; GDSC2; CTRP2 0.6587 8.5582 -0.6701 39.1202
EHEB GDSC1; CTRP2 0.7605 10.6433 -1.4033 40.0054
CESS GDSC1; GDSC2 0.7996 5.5564 -1.4473 15.8501
MLMA GDSC1; GDSC2 0.8251 7.6658 -2.4798 21.2278
KY821 GDSC1; GDSC2 0.857 7.8353 -2.5375 21.4022
Hs 445 GDSC2 0.8965 7.503 -2.3382 20.3236
MOLT-13 GDSC1; GDSC2; CTRP2 0.9231 10.9737 -1.3754 39.4068
Peer CTRP2 0.9845 9.074 -0.523 37.6506
NOMO-1 GDSC1; GDSC2; CTRP2 1.0076 9.5789 -0.7018 37.9272
MN-60 GDSC1; GDSC2 1.0835 4.4488 -0.6553 10.2184
MHH-CALL-3 CTRP2 1.123 9.8658 -0.6986 37.5222
ALL-SIL GDSC1; GDSC2; CTRP2 1.1827 7.3061 0.3475 34.8989
IM-9 GDSC1; GDSC2 1.2565 3.2893 0.0615 5.2371
KM-H2 GDSC1; GDSC2; CTRP2 1.3571 8.3961 0.1382 34.8374
Mono-Mac-6 GDSC1; GDSC2; CTRP2 1.3907 9.4644 -0.2518 35.6618
SU-DHL-1 CTRP2 1.4369 8.9936 -0.0118 34.9395
ME1 GDSC1; GDSC2 1.4484 7.3547 -1.8119 15.987
Mono-Mac-1 CTRP2 1.5489 13.7658 -1.9935 38.392
P3HR-1 CTRP2 1.7201 16.0107 -2.8807 39.129
U266B1 GDSC1; GDSC2; CTRP2 1.9905 12.7167 -1.0697 35.4969
CCRF-CEM GDSC1; GDSC2 2.0454 6.2423 -0.8093 8.6897
OCI-AML-5 GDSC1; GDSC2; CTRP2 2.1514 9.6814 0.4515 31.4197
SEM CTRP2 2.5128 10.7578 0.3483 30.6171
HDLM-2 GDSC1; GDSC2; CTRP2 2.5623 13.302 -0.7788 33.2517
GDM-1 GDSC1; GDSC2; CTRP2 3.3864 10.9506 1.1334 25.7941
AML-193 CTRP2 4.1037 11.7421 1.4516 22.8756
HPB-ALL CTRP2 4.1309 10.662 1.9963 20.8684
BL-41 GDSC1; GDSC2; CTRP2 4.134 16.6774 -1.5472 27.7094
ME1 CTRP2 4.8535 18.4616 -1.1826 28.5486
REC-1 CTRP2 4.9322 7.0866 4.4452 9.2313
Karpas-620 GDSC1; GDSC2; CTRP2 5.6876 16.4063 0.5631 22.1645
Toledo CTRP2 6.0056 9.0661 3.7672 4.0412
KMM-1 CTRP2 6.275 11.8227 3.3451 10.8686
MC116 GDSC1; CTRP2 7.2502 8.2314 5.7201 0.1934
⏷ Show the Full List of 219 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 0.2948 12.7832 -2.8117 43.2699
TE8 CTRP2 1.8176 10.6775 -0.7673 31.7914
TE-6 GDSC1; GDSC2; CTRP2 -1.9389 4.7911 -2.509 49.8731
TE-5 GDSC1; GDSC2; CTRP2 -1.7362 7.7345 -2.9619 51.2877
OE21 GDSC1; GDSC2; CTRP2 -1.6685 3.519 -1.842 51.2735
OE33 GDSC1; GDSC2; CTRP2 -0.9298 7.1279 -1.8881 47.2745
KYSE-70 GDSC1; GDSC2; CTRP2 -0.4954 6.9275 -1.352 44.8399
TE-15 GDSC1; GDSC2 -0.3646 3.8538 -1.6785 21.1762
EC-GI-10 GDSC1; GDSC2; CTRP2 -0.3551 9.4123 -2.0799 44.9461
KYSE-410 GDSC1; GDSC2; CTRP2 0.1074 5.5266 -0.3011 40.5605
KYSE-140 GDSC1; GDSC2; CTRP2 0.2128 7.9575 -0.9285 41.2833
TE-4 GDSC1; GDSC2; CTRP2 0.2403 4.9026 -0.1604 35.591
KYSE-520 GDSC1; GDSC2; CTRP2 0.5941 8.7084 -0.7963 39.5937
TE-8 GDSC1; GDSC2 0.6251 5.8108 -1.7246 17.9687
T.T GDSC1; GDSC2 0.8572 5.317 -1.2786 14.6872
KYSE-270 GDSC1; GDSC2 0.8968 5.6091 -1.391 15.2258
KYSE-450 GDSC1; GDSC2; CTRP2 1.2482 7.906 0.2054 35.0422
TE-11 GDSC1; CTRP2 1.58 10.0574 -0.3022 35.1508
TE-14 CTRP2 1.7276 9.2411 0.194 33.4584
KYSE-180 GDSC1; GDSC2; CTRP2 1.7486 10.6825 -0.3977 34.8254
TE-10 GDSC1; CTRP2 2.4811 8.5511 1.2693 27.9252
TE-9 GDSC1; GDSC2; CTRP2 3.538 9.9219 1.7599 23.2532
OE19 GDSC1; GDSC2; CTRP2 3.9971 13.8431 0.3305 26.6745
TE-1 GDSC1; GDSC2; CTRP2 4.798 13.0148 1.4728 21.1449
COLO 680N GDSC1; GDSC2; CTRP2 5.9292 18.9091 -0.4842 24.6234
KYSE-30 CTRP2 7.024 13.0264 3.3324 9.5905
KYSE-150 GDSC1; GDSC2; CTRP2 7.8306 16.0996 2.4165 11.841
KYSE-510 GDSC1; CTRP2 8.4999 14.1479 3.8104 5.5551
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 -2.3611 16.0348 -6.9639 52.52
PaTu 8988s CTRP2 -8.3997 11.7727 -11.5849 67.2152
DAN-G GDSC1; GDSC2; CTRP2 -2.7308 2.0588 -2.8506 55.0638
PK-59 CTRP2 -2.5148 7.0531 -3.5903 54.8836
Hs 766T GDSC1; GDSC2; CTRP2 -1.3193 6.5131 -2.1246 49.2628
TCC-Pan2 CTRP2 -1.0277 11.0228 -3.4342 48.2864
PK-45H CTRP2 -0.7636 15.5003 -5.1031 47.8298
SNU-213 CTRP2 -0.5449 7.7908 -1.6894 45.3908
MIA PaCa-2 GDSC1; GDSC2; CTRP2 -0.4745 4.8068 -0.7742 43.9978
PaTu 8988t GDSC1; GDSC2; CTRP2 -0.439 9.9815 -2.3926 45.5236
Panc 08.13 GDSC1; GDSC2; CTRP2 -0.3266 8.0968 -1.5601 44.3319
Panc 05.04 CTRP2 -0.2217 22.2421 -7.7267 47.1025
Panc 04.03 GDSC1; GDSC2; CTRP2 -0.1863 8.0562 -1.3943 43.5589
AsPC-1 GDSC1; GDSC2; CTRP2 0.1321 12.9619 -3.0569 44.0116
HPAF-II GDSC1; CTRP2 0.1483 8.2706 -1.1109 41.8223
PL4 GDSC1; GDSC2 0.2978 3.8967 -1.0684 15.2337
KP-1N GDSC1; GDSC2 0.3589 4.485 -1.3019 16.4208
BxPC-3 GDSC1; GDSC2; CTRP2 0.4144 6.8327 -0.3319 39.3832
Panc 02.03 GDSC1; GDSC2; CTRP2 0.4249 3.7275 -0.8684 13.5849
SW1990 GDSC1; GDSC2; CTRP2 0.4703 7.7551 -0.579 39.6594
Panc 10.05 GDSC1; GDSC2 0.5179 10.6467 -4.2308 28.9826
CFPAC-1 GDSC1; GDSC2; CTRP2 0.5636 10.3923 -1.5034 40.8421
Panc 03.27 GDSC1; GDSC2; CTRP2 0.7545 6.2348 0.2182 36.7905
L3.3 CTRP2 0.8287 7.7784 -0.2003 37.5216
HuP-T4 GDSC1; GDSC2; CTRP2 0.9437 8.016 -0.1624 37.0161
MZ-PC-1 GDSC1 1.0466 3.2504 -0.0867 8.3988
YAPC GDSC1; GDSC2; CTRP2 1.1013 9.8397 -0.7106 37.6205
PaTu 8902 GDSC1; GDSC2; CTRP2 1.6391 11.096 -0.6917 35.8094
KP-3 GDSC1; GDSC2; CTRP2 1.6645 8.7173 0.3396 33.2794
HPAC GDSC1; GDSC2; CTRP2 1.8394 11.8286 -0.8155 35.4415
KP-4 GDSC1; GDSC2; CTRP2 1.8581 10.3326 -0.1326 33.8596
QGP-1 GDSC1; CTRP2 2.0787 7.335 1.3062 29.0436
SU.86.86 GDSC2; CTRP2 2.4375 11.1862 -0.3997 28.9227
PSN1 GDSC1; GDSC2; CTRP2 2.7694 12.4691 -0.1843 31.2819
KP-2 GDSC1; GDSC2; CTRP2 3.7144 15.8185 -0.8984 30.5144
Capan-1 GDSC1; GDSC2; CTRP2 4.13 13.842 0.4542 25.99
SUIT-2 GDSC1; GDSC2; CTRP2 4.2637 14.5316 0.2387 26.2894
HuP-T3 GDSC1; GDSC2; CTRP2 4.5022 16.5115 -0.5241 27.7645
SNU-410 CTRP2 6.5152 20.8001 -0.9449 24.6528
Capan-2 GDSC1; GDSC2; CTRP2 8.6222 22.0467 0.0767 18.3003
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 75 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -0.6363 12.8992 -4.2412 45.1519
Hs 294T CTRP2 -3.4865 13.0889 -6.8671 56.1802
WM88 CTRP2 -3.347 13.4779 -6.8818 55.6857
Mel Ho GDSC1; CTRP2 -1.9184 4.478 -2.2736 52.6178
MZ-MEL-2 GDSC1 -1.6818 1.5542 -2.0949 35.7942
LOX-IMVI GDSC1; GDSC2; CTRP2 -1.6603 3.7383 -1.8652 51.2102
CHL-1 GDSC1; GDSC2 -1.6104 0.6941 -1.7715 27.0254
WM266-4 CTRP2 -1.2594 17.5307 -6.5266 49.4466
COLO 741 CTRP2 -1.2038 11.6238 -3.8665 49.0301
451Lu GDSC1 -1.0772 1.8911 -1.5601 29.0422
Hs 852.T CTRP2 -1.0011 43.1202 -18.6491 49.4344
SK-MEL-5 GDSC1; CTRP2 -0.871 3.8703 -1.0394 46.3096
A101D GDSC1; GDSC2; CTRP2 -0.8214 4.1269 -1.0255 46.0382
COLO 792 GDSC1; GDSC2; CTRP2 -0.6421 5.1138 -1.0213 45.1424
IGR-39 CTRP2 -0.5518 16.8687 -5.5161 47.3327
RPMI-7951 GDSC1; GDSC2; CTRP2 -0.5334 7.2132 -1.4843 45.1468
Hs 895.T CTRP2 -0.528 25.8896 -9.7748 48.1222
WM35 GDSC1; GDSC2 -0.5194 3.6623 -1.7411 22.1198
Hs 938.T GDSC1 -0.3528 3.724 -1.6058 25.4027
A-431 GDSC1 -0.3269 7.2308 -3.2802 33.1175
WM1552C GDSC1; GDSC2 -0.3126 5.1195 -2.2348 23.908
CP50-MEL-B GDSC1 -0.1882 3.706 -1.4369 23.5347
M14 GDSC1; GDSC2 -0.1851 7.9423 -3.5022 28.8436
A-375 GDSC1; GDSC2; CTRP2 -0.1164 7.5237 -1.1343 42.9319
G-mel GDSC1 -0.0095 2.5035 -0.699 17.5367
SH-4 GDSC1; GDSC2 0.0814 5.6435 -2.1256 21.9303
IST-MEL1 GDSC1; GDSC2 0.0884 2.6712 -0.679 13.6106
GAK GDSC1; GDSC2 0.123 4.9528 -1.7476 19.7754
G-361 GDSC1; GDSC2; CTRP2 0.1666 10.0312 -1.7721 42.6319
HMCB CTRP2 0.2411 16.8463 -4.7201 44.8089
MDA-MB-435S CTRP2 0.4 10.0115 -1.5181 41.4496
IPC-298 GDSC1; CTRP2 0.4882 7.4688 -0.4604 39.3579
DJM-1 GDSC1 0.5559 6.0286 -1.8933 23.0157
WM793 GDSC1; GDSC2; CTRP2 0.56 8.7865 -0.8626 39.8383
COLO 679 GDSC1; GDSC2 0.561 3.3597 -0.5631 11.2444
WM115 GDSC1; GDSC2; CTRP2 0.5684 13.5102 -2.8588 42.4416
A-388 GDSC1 0.5797 5.2143 -1.4669 20.3178
CP66-MEL GDSC1 0.5809 4.9283 -1.3235 19.3704
A2058 GDSC1; GDSC2; CTRP2 0.6477 6.7252 -0.0442 37.8405
Mel JuSo GDSC1; GDSC2; CTRP2 0.6729 8.6212 -0.6788 39.0841
MZ-MEL-7 GDSC1 0.7406 7.3815 -2.4094 25.0331
MeWo GDSC1; GDSC2; CTRP2 0.7646 11.3242 -1.6903 40.4147
IGR-1 GDSC1; GDSC2; CTRP2 0.8526 8.0428 -0.5932 34.5102
LB2518-MEL GDSC1 0.8959 5.2186 -1.1967 17.2646
SK-MEL-3 GDSC1; CTRP2 1.0469 12.1327 -1.7556 39.5807
HMV-II GDSC2 1.0958 7.7781 -2.3096 19.581
K029AX CTRP2 1.2363 16.7538 -3.7027 41.3408
LB373-MEL-D GDSC1 1.3298 3.9048 -0.1875 8.2255
COLO 783 GDSC1 1.354 3.1625 0.1977 5.1548
HT-144 GDSC1; GDSC2; CTRP2 1.3778 13.209 -1.9077 38.7744
WM983B CTRP2 1.3876 11.6038 -1.1733 37.5414
RVH-421 GDSC1; CTRP2 1.3969 11.8213 -1.2606 37.667
SK-MEL-1 GDSC1; GDSC2; CTRP2 1.4313 8.3891 0.22 34.375
WM278 GDSC1; GDSC2 1.4321 7.8112 -2.0525 17.3069
COLO 829 GDSC1; GDSC2; CTRP2 1.7174 7.666 0.47 28.3368
Hs 940.T GDSC1; CTRP2 1.7232 13.9357 -1.9001 37.7398
UACC-62 GDSC1; GDSC2; CTRP2 1.779 11.4077 -0.6874 35.3616
CJM [Human melanoma] CTRP2 1.8466 9.7877 0.0896 33.3442
SK-MEL-30 CTRP2 1.9309 9.6048 0.2548 32.6458
Hs 944.T CTRP2 1.9326 15.1199 -2.2517 37.6858
IGR-37 GDSC1; GDSC2; CTRP2 2.3994 13.2237 -0.9015 33.9723
UACC-257 GDSC1; GDSC2; CTRP2 2.4993 11.3788 0.053 31.4482
WM1799 CTRP2 3.1572 24.8903 -5.8809 39.0305
SK-MEL-24 GDSC1; GDSC2; CTRP2 3.2159 11.7468 0.5928 27.9316
Hs 936.T CTRP2 3.2164 14.4824 -0.7135 31.3451
COLO 800 GDSC1; CTRP2 3.4412 16.2714 -1.3729 32.2047
WT2-iPS GDSC1; GDSC2; CTRP2 4.0698 21.0239 -3.1485 33.9193
SK-MEL-2 GDSC1; GDSC2; CTRP2 5.7846 8.5555 4.5663 6.7333
SK-MEL-31 GDSC1; CTRP2 6.1396 18.9144 -0.3115 23.7524
Hs 839.T CTRP2 6.211 24.6808 -3.1354 29.7417
Hs 688(A).T CTRP2 7.2413 20.2805 -0.1025 21.1226
Malme-3M CTRP2 8.6037 12.4946 4.6197 2.4961
Hs 934.T CTRP2 9.0023 27.4904 -2.3244 23.602
SK-MEL-28 GDSC1; CTRP2 11.2596 29.2299 -1.5424 18.7075
EquiPSC Line K2 GDSC1 1.791 5.9773 -0.8641 11.8387
⏷ Show the Full List of 75 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-GT-4 GDSC1; GDSC2 -1.6218 3.0029 -2.5786 31.0167
KYAE-1 GDSC1; GDSC2 -1.1971 1.0551 -1.4131 23.1836
FLO-1 GDSC1; GDSC2 -1.1807 4.4209 -2.7494 29.7666
OACP4 C GDSC1; GDSC2 -0.6473 4.8091 -2.4058 26.025
TE-12 GDSC1 -0.4159 3.2191 -1.4335 24.6385
ESO-51 GDSC1; GDSC2 -0.0461 3.6212 -1.2593 17.5879
ESO-26 GDSC1; GDSC2 0.9347 3.9104 -0.51 9.7428
OACM5.1 C GDSC1; GDSC2 0.9401 4.6393 -0.8698 11.9668
HCE-4 GDSC1 1.3219 9.151 -2.8105 24.7927
KYSE-220 GDSC1; GDSC2 1.3825 4.0848 -0.2364 6.7814
KYSE-50 GDSC1; GDSC2 1.9144 5.4577 -0.5204 7.2519
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 -1.9811 4.0919 -2.2687 53.0346
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -5.4168 1.4191 -5.5694 71.1227
KP-N-SI9s CTRP2 -3.0992 5.0881 -3.6904 58.2901
NB69 GDSC1; GDSC2 -2.7582 1.3531 -3.203 39.4093
SJNB-14 GDSC1; GDSC2 -2.1534 3.6058 -3.3863 36.6646
KP-N-YS GDSC1 -2.0894 24.6062 -13.4672 48.1439
Kelly GDSC1; GDSC2; CTRP2 -1.9713 9.611 -3.8831 52.0805
CHP-212 GDSC1; GDSC2; CTRP2 -0.7615 5.7691 -1.3098 46.0375
SK-N-DZ GDSC1; GDSC2; CTRP2 -0.6914 7.7875 -1.8469 46.1627
SJNB-5 GDSC1 -0.5439 2.7833 -1.3664 24.8647
SK-N-BE(2)-M17 GDSC1; GDSC2 -0.5186 2.199 -1.0889 18.4145
SK-N-MC-IXC GDSC1 -0.4749 2.7363 -1.2751 23.9049
GI-ME-N GDSC1; GDSC2 -0.3286 6.5544 -2.9495 27.2223
NH-6 CTRP2 -0.1289 10.7935 -2.3955 44.3589
NH-12 GDSC1; GDSC2 -0.0638 5.6907 -2.2817 23.229
NB1 GDSC1; GDSC2; CTRP2 -0.0443 4.6395 -0.2763 41.1433
SK-N-AS GDSC1; GDSC2; CTRP2 0.0574 7.7147 -1.0112 42.0368
SK-N-BE(2) CTRP2 0.2586 16.6766 -4.6236 44.7053
SJNB-13 GDSC1; GDSC2 0.4131 3.4304 -0.7333 12.794
GOTO GDSC1; GDSC2 0.5906 3.9621 -0.8347 12.8338
SK-N-SH GDSC1; GDSC2; CTRP2 0.765 12.445 -2.1818 41.0654
SJNB-6 GDSC1 0.993 4.5001 -0.7559 13.7406
CHP-134 GDSC1; GDSC2 1.0743 7.0109 -1.9437 17.771
SJNB-10 GDSC1; GDSC2 1.3182 5.1419 -0.8121 10.5336
SK-N-FI GDSC1; GDSC2; CTRP2 1.3294 12.1189 -1.4623 38.2242
CHP-126 GDSC1; CTRP2 1.3716 9.7515 -0.3908 36.0377
SJNB-7 GDSC1; GDSC2 1.4342 4.0676 -0.1887 6.352
LA-N-6 GDSC1 1.4348 5.4316 -0.8647 12.9856
MHH-NB-11 GDSC1; CTRP2 1.5046 13.1262 -1.7428 38.138
TGW GDSC1; GDSC2 1.7644 7.028 -1.4031 12.8614
SJNB-17 GDSC1 1.8008 5.7866 -0.7631 11.0835
IMR-5 GDSC1; GDSC2 1.975 3.5747 0.4057 1.7005
NB(TU)1 GDSC1; GDSC2 2.1524 4.1865 0.2338 2.3509
SJNB-12 GDSC1; GDSC2 2.5393 6.4155 -0.5575 6.1553
SiMa GDSC1; GDSC2; CTRP2 2.7674 10.673 0.6437 29.0329
KP-N-YN GDSC1; GDSC2; CTRP2 6.0624 12.3215 2.9209 12.9976
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -2.598 1.9316 -2.6594 57.1711
SNU-478 CTRP2 -1.1633 7.117 -2.1386 48.4949
HuCC-T1 GDSC1; GDSC2; CTRP2 0.2808 9.2055 -1.3224 41.6177
SNU-869 CTRP2 1.2584 12.9606 -1.9141 39.1483
SNU-1196 CTRP2 1.3881 12.2832 -1.4766 38.0637
SNU-308 CTRP2 1.718 12.526 -1.2544 36.6617
HuH-28 CTRP2 4.876 13.6401 1.2337 21.7814
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MRK-nu-1 GDSC1; GDSC2 -3.9099 1.1207 -4.3917 45.5333
SK-BR-3 CTRP2 -3.0458 4.7036 -3.5447 58.2598
CAL-148 GDSC2; CTRP2 -2.6122 0.6821 -2.6215 53.9158
Hs 578T GDSC1; GDSC2; CTRP2 -2.2647 4.1883 -2.7159 48.787
UACC-812 GDSC2; CTRP2 -2.1878 6.2232 -2.9891 53.6435
Evsa-T GDSC1; GDSC2 -2.0802 2.4242 -2.835 31.3593
CAL-51 GDSC1; GDSC2; CTRP2 -1.6699 4.4197 -1.9931 48.2827
OCUB-M GDSC1; GDSC2 -1.4179 1.5712 -1.8142 23.8909
DU4475 GDSC1; GDSC2; CTRP2 -1.1922 3.4015 -1.3939 41.9369
MFM-223 GDSC1; GDSC2 -1.1423 1.9341 -1.646 21.947
UACC-893 GDSC1; GDSC2 -1.1244 5.3136 -3.109 28.5751
CAL-120 GDSC1; GDSC2; CTRP2 -0.9666 5.5781 -1.4848 44.5088
MDA-MB-361 GDSC1; GDSC2; CTRP2 -0.9597 6.0577 -1.603 44.6194
MCF-7 GDSC1; GDSC2; CTRP2 -0.6882 6.745 -1.5057 43.3603
MDA-MB-415 GDSC1; GDSC2 -0.6253 5.047 -2.4981 24.1861
MDA-MB-330 GDSC1; GDSC2 -0.5822 4.6573 -2.2706 22.9755
HCC1500 GDSC1; GDSC2; CTRP2 -0.5804 10.6591 -3.1914 42.1563
JIMT-1 GDSC1; GDSC2; CTRP2 -0.3281 5.4395 -0.7547 40.6954
HCC1569 GDSC1; GDSC2 -0.2629 9.3847 -4.2863 29.6949
HCC1954 GDSC1; GDSC2; CTRP2 -0.2142 4.3562 -0.41 39.5157
MDA-MB-175-VII GDSC1; GDSC2 -0.177 5.3948 -2.2417 21.4705
HCC202 GDSC1; CTRP2 -0.1275 9.5904 -1.9073 43.8935
MDA-MB-468 GDSC1; GDSC2; CTRP2 -0.0162 7.198 -1.1864 36.8527
CAL-85-1 GDSC1; GDSC2; CTRP2 0.0286 8.7204 -1.4059 40.488
AU565 GDSC1; GDSC2 0.065 5.6377 -2.1377 20.1892
EFM-192A GDSC1; GDSC2 0.1369 3.8193 -1.1807 14.9474
HCC1419 GDSC1; GDSC2; CTRP2 0.1447 5.9732 -0.3748 38.1122
HCC2157 GDSC1 0.2376 3.3568 -0.8615 17.5888
HCC70 GDSC1; GDSC2 0.3521 8.0984 -3.1026 23.6387
EFM-19 GDSC1; GDSC2 0.362 8.2764 -3.1827 23.9318
BT-20 GDSC1; GDSC2; CTRP2 0.9102 10.7998 -1.3142 37.3993
HCC38 GDSC1; GDSC2; CTRP2 0.9228 7.6451 -0.0515 34.6688
MDA-MB-436 GDSC1; GDSC2 0.9256 6.4733 -1.7989 15.9497
BT-549 GDSC1; GDSC2; CTRP2 1.0776 14.8133 -2.9467 39.3651
CAMA-1 GDSC1; GDSC2; CTRP2 1.0851 10.9209 -1.1851 36.6205
HCC1143 GDSC1; GDSC2; CTRP2 1.117 7.3031 0.2773 33.1871
MDA-MB-453 GDSC1; GDSC2; CTRP2 1.22 8.3792 -0.0019 33.593
BT-483 GDSC1; GDSC2 1.2627 8.9424 -2.7545 19.6108
MDA-MB-157 GDSC1; GDSC2; CTRP2 1.3888 8.2797 0.2165 32.4987
HCC1599 GDSC2 1.4959 9.6866 -3.6602 17.4361
COLO 824 GDSC1; GDSC2 1.5986 6.9926 -1.5132 12.7165
ZR-75-30 GDSC1; GDSC2; CTRP2 1.6162 10.4322 -0.4254 33.4169
HCC2218 GDSC1; GDSC2; CTRP2 1.7276 12.8683 -1.4016 35.1561
HMC-1-8 CTRP2 1.7443 10.8892 -0.4929 35.0513
T-47D GDSC1; GDSC2; CTRP2 1.8432 16.4554 -2.9738 37.4029
HCC1395 GDSC1; GDSC2; CTRP2 2.474 12.2157 -0.3575 30.8525
BT-474 GDSC1; GDSC2; CTRP2 2.5339 13.3095 -0.8101 31.7588
HCC1428 GDSC1; GDSC2; CTRP2 2.6836 10.5807 0.6009 27.7172
HCC1187 GDSC1; GDSC2 2.8799 9.129 -1.6245 10.4861
MDA-MB-231 GDSC1; GDSC2; CTRP2 2.8947 15.4739 -1.4976 32.3146
HCC1937 GDSC1; GDSC2; CTRP2 4.5011 16.5311 -0.5347 26.4677
ZR-75-1 CTRP2 4.6858 13.6384 1.0633 22.7807
HDQ-P1 GDSC1; GDSC2; CTRP2 5.3214 20.574 -1.8314 27.7857
HCC1806 GDSC1; GDSC2; CTRP2 5.4133 16.7922 0.1359 22.7948
KPL-1 CTRP2 6.2122 7.3704 5.5155 2.3988
Hs 578Bst CTRP2 10.3038 24.5289 0.0659 15.8564
BT 145 CTRP2 -4.9664 13.835 -8.7293 59.5222
BT164 CTRP2 -4.2794 13.4972 -7.8683 58.0686
BT 112 CTRP2 -1.699 11.6355 -4.3912 50.8731
BT 422 CTRP2 -1.0552 16.7111 -5.9468 48.8293
BT 231 CTRP2 -0.7943 9.5961 -2.6192 47.0708
BT147 CTRP2 -0.6735 14.7912 -4.6923 47.4437
BT 271 CTRP2 -0.5319 19.1882 -6.577 47.5555
BT 428 CTRP2 -0.384 12.6507 -3.4502 45.9922
BT 286 CTRP2 -0.2518 11.5967 -2.8607 45.1665
BT 330 CTRP2 0.165 14.6836 -3.7973 44.4555
BT 179 CTRP2 0.5608 32.6732 -12.0768 46.6212
BT 131 CTRP2 0.5821 12.7448 -2.5015 42.0272
BT 239 CTRP2 1.1062 14.5444 -2.7935 40.7471
BT 172 CTRP2 1.5006 10.964 -0.7757 36.4237
BT 416 CTRP2 1.5346 9.5667 -0.1432 34.9295
BT 248 CTRP2 1.6839 16.1605 -2.987 39.3589
BT 440 CTRP2 1.7156 17.7991 -3.7402 40.1323
BT 224 CTRP2 2.0297 22.1417 -5.5538 41.0593
BT 159 CTRP2 2.0925 19.5018 -4.2069 39.6971
BT 504 CTRP2 2.1189 16.7115 -2.8321 38.0113
BT 482 CTRP2 2.9408 16.4084 -1.9069 34.4679
BT 228 CTRP2 3.1213 17.726 -2.3813 34.8343
BT 216 CTRP2 3.4965 20.6712 -3.4876 35.6454
BT 359 CTRP2 3.9578 12.5933 0.9019 25.0521
BT 232 CTRP2 4.3336 19.4573 -2.1362 31.6348
BT 333 CTRP2 4.7592 18.9223 -1.4946 29.4348
BT 187 CTRP2 4.9513 21.2725 -2.4987 31.0068
BT 340 CTRP2 5.1397 23.126 -3.2616 31.9409
BT 444 CTRP2 5.2601 31.3011 -7.2433 36.6029
BT 328 CTRP2 5.3148 21.6708 -2.3848 30.0701
BT 139 CTRP2 6.4555 26.8183 -4.002 30.7339
BT 245 CTRP2 7.487 22.1259 -0.828 22.6144
BT 320 CTRP2 9.4682 29.6225 -3.0271 24.3247
BT 498 CTRP2 9.655 37.7451 -6.9066 30.0132
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -0.3193 5.2759 -0.7067 43.1758
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC1; GDSC2; CTRP2 -4.9094 2.4685 -5.1573 67.9687
YH-13 GDSC1; GDSC2; CTRP2 -1.3482 7.4809 -2.4568 49.451
Hs 683 GDSC1; CTRP2 -1.143 6.7644 -2.0072 48.3515
YKG-1 GDSC1; CTRP2 -0.9287 10.7594 -3.2227 47.8468
H4 GDSC1; GDSC2 -0.9218 2.2005 -1.5142 22.5162
GMS-10 CTRP2 -0.7272 15.3356 -4.9918 47.6924
SK-MG-1 GDSC1; GDSC2 -0.5285 4.1639 -1.9848 23.4592
M059K CTRP2 -0.4374 16.9615 -5.4452 46.9947
PFSK-1 GDSC1 -0.3945 3.649 -1.6116 25.6471
AM-38 GDSC1; GDSC2; CTRP2 -0.3076 3.4344 -0.3875 42.517
MOG-G-UVW GDSC1; GDSC2 -0.3058 2.8455 -1.1525 17.9359
A-172 GDSC2; CTRP2 -0.1801 16.0785 -5.2615 44.4182
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 0.0061 3.7046 -1.2493 17.3395
Becker GDSC1; GDSC2; CTRP2 0.007 8.9717 -1.8641 40.3293
KALS-1 GDSC1; GDSC2; CTRP2 0.0361 10.931 -2.28 43.6545
D-566MG GDSC1 0.0561 2.7876 -0.7652 17.7118
D-423MG GDSC1 0.0588 4.1372 -1.4085 22.1907
SW1088 GDSC1; GDSC2; CTRP2 0.0925 10.4022 -2.0016 43.1653
KNS-81 CTRP2 0.1134 14.2707 -4.1244 42.7088
MOG-G-CCM GDSC1; GDSC2 0.2309 5.4761 -1.9074 20.27
ONS-76 GDSC1; GDSC2; CTRP2 0.2718 5.5531 -0.1284 39.5071
D-263MG GDSC1; GDSC2 0.3457 4.7187 -1.4293 17.2108
LN-405 GDSC1; GDSC2 0.4734 7.0318 -2.4652 22.2786
LNZTA3WT4 GDSC1; GDSC2 0.5093 3.5316 -0.6948 12.2339
T98G GDSC1; GDSC2; CTRP2 0.5965 11.4984 -2.3639 39.0533
42-MG-BA GDSC1; GDSC2; CTRP2 0.7022 8.9821 -0.7867 39.1776
GaMG GDSC1; GDSC2; CTRP2 0.7313 14.587 -3.1863 42.2644
GOS-3 CTRP2 0.8244 27.3329 -9.2114 45.4243
KNS-81-FD GDSC1 0.8255 4.3415 -0.8183 14.8356
M059J GDSC1; GDSC2 0.9539 2.7579 0.0824 5.945
U-118MG GDSC1; GDSC2; CTRP2 0.9999 7.3998 -0.179 32.83
D-542MG GDSC1 1.0662 5.2817 -1.0859 15.8569
KINGS-1 GDSC1; GDSC2 1.0714 8.3111 -2.5962 21.0268
GI-1 GDSC1; GDSC2 1.0911 3.5325 -0.1912 7.2802
SF295 GDSC1; CTRP2 1.115 11.5865 -1.4444 38.8816
LN-18 GDSC1; GDSC2; CTRP2 1.1816 6.8924 0.4838 34.5312
D-247MG GDSC1 1.3063 3.7478 -0.1277 7.8365
SF539 GDSC1; GDSC2; CTRP2 1.3449 8.4254 0.1139 34.9403
D-502MG GDSC1 1.4579 5.3171 -0.7899 12.3654
DK-MG GDSC1; GDSC2; CTRP2 1.6183 11.1091 -0.7188 35.9315
CCF-STTG1 CTRP2 1.7639 12.662 -1.2707 36.5529
DBTRG-05MG GDSC1; GDSC2; CTRP2 1.7673 8.5204 0.5265 32.4284
NMC-G1 GDSC1; CTRP2 1.8799 9.8217 0.1098 33.1864
Onda 10 GDSC1 1.888 4.5154 -0.0841 5.8093
Onda 11 GDSC1 2.0012 4.321 0.0813 4.3185
KNS-60 CTRP2 2.1218 17.2583 -3.6415 36.6464
D-392MG GDSC1; GDSC2 2.1986 11.5786 -3.3266 21.0762
CAS-1 GDSC1; GDSC2; CTRP2 2.3104 9.8677 0.5355 30.6969
TM-31 CTRP2 2.439 15.6351 -2.0092 35.9374
Daoy GDSC1; GDSC2; CTRP2 2.5939 12.7307 -0.4793 32.4873
GB-1 GDSC1; GDSC2; CTRP2 2.8846 12.3777 -0.0284 30.5638
SNU-1105 CTRP2 2.9069 13.6832 -0.6254 31.9615
SF126 GDSC1; CTRP2 3.4166 14.0778 -0.3283 29.9049
SF268 GDSC1; GDSC2; CTRP2 3.7989 11.9457 1.0631 24.9396
SNU-489 CTRP2 3.8795 17.5488 -1.5985 31.6143
LN-229 GDSC1; GDSC2; CTRP2 3.9806 9.0751 2.5905 19.0056
SW1783 GDSC1; GDSC2; CTRP2 4.0236 16.68 -1.0389 30.0912
SNU-626 CTRP2 4.4363 13.0502 1.1252 23.164
SNU-738 CTRP2 4.6117 15.2929 0.1779 25.6463
SNU-201 CTRP2 4.7733 14.0379 0.9445 22.9633
SNB-75 GDSC1; CTRP2 5.167 12.512 2.0532 18.228
KG-1-C CTRP2 5.5425 22.9661 -2.8383 30.4542
U-87MG ATCC GDSC1; GDSC2; CTRP2 6.2402 17.8512 0.3034 21.8287
U-251MG GDSC1; GDSC2; CTRP2 6.5046 15.4518 1.7184 16.7139
8-MG-BA GDSC1; GDSC2; CTRP2 8.0341 18.0013 1.6322 14.3367
KNS-42 GDSC1; CTRP2 9.7104 23.9459 -0.0657 17.0601
SNU-466 CTRP2 9.8388 21.4622 1.2224 13.0154
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1; GDSC2 -0.2984 3.1996 -1.3075 18.8131
ETK-1 GDSC1; GDSC2 0.2991 2.2737 -0.2857 10.4368
TGBC24TKB GDSC1; GDSC2 0.3369 3.7515 -0.9611 14.4502
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 -6.6523 0.7146 -6.801 76.0078
AN3-CA GDSC1; GDSC2; CTRP2 -3.7944 5.1387 -4.6275 59.0438
JHUEM-1 CTRP2 -3.4073 4.1428 -3.8205 60.2437
JHUEM-2 CTRP2 -2.9485 2.7578 -3.1064 58.8195
HEC-151 CTRP2 -1.502 5.7015 -2.1001 50.2244
JHUEM-3 CTRP2 -0.82 9.4494 -2.5902 47.1613
HEC-1-B CTRP2 -0.4894 8.5929 -1.9145 45.3507
HEC-59 CTRP2 -0.3457 8.5692 -1.7514 44.6069
MFE-280 GDSC1; GDSC2 0.3364 3.0885 -0.6383 12.4708
RL95-2 GDSC1; GDSC2; CTRP2 0.4683 7.6449 -0.5426 39.5971
ESS-1 GDSC1; GDSC2; CTRP2 0.836 11.4975 -1.692 40.178
MFE-319 GDSC1; GDSC2; CTRP2 0.9415 6.3389 0.3923 35.6404
EN GDSC1; GDSC2; CTRP2 1.3736 11.6153 -1.6425 35.2405
EFE-184 CTRP2 2.4038 11.6437 -0.1638 32.2769
KLE GDSC1; GDSC2; CTRP2 2.6747 12.1524 -0.1294 31.4105
HEC-251 CTRP2 2.7191 12.1937 -0.1049 31.2229
HEC-6 CTRP2 2.8868 14.5988 -1.0832 33.0193
HEC-1-A CTRP2 2.8889 11.4544 0.4069 29.3719
HEC-108 CTRP2 3.0139 16.79 -2.0241 34.4915
HEC-50B CTRP2 4.1818 14.3646 0.2457 26.4661
MFE-296 GDSC1; GDSC2; CTRP2 4.7946 16.6256 -0.3207 26.5865
HEC-265 CTRP2 7.7021 18.4723 1.1521 16.5066
Ishikawa (Heraklio) 02 ER- CTRP2 1.0092 14.3405 -2.7957 41.0351
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 GDSC1; GDSC2; CTRP2 -2.4395 7.5946 -3.6798 54.3992
LB2241-RCC GDSC1 -1.713 1.4152 -2.0838 35.9512
KMRC-2 CTRP2 -1.6911 20.8195 -8.4802 50.5382
BB65-RCC GDSC1 -1.5786 5.6797 -3.7271 40.4933
LB1047-RCC GDSC1 -1.4209 0.9024 -1.616 31.4691
KTCTL-1M GDSC1 -1.2099 1.7419 -1.6484 30.3629
KTCTL-140 GDSC1 -1.1055 2.1161 -1.6761 29.9042
HA7-RCC GDSC1 -1.0348 2.2779 -1.6648 29.4235
KTCTL-26A GDSC1 -1.0261 2.4647 -1.7313 29.7617
KTCTL-21 GDSC1 -0.8536 3.7082 -2.0957 30.7669
SW13 GDSC1; GDSC2 -0.7015 2.9668 -1.6087 22.1192
KTCTL-195 GDSC1; GDSC2 -0.5652 2.4161 -1.2289 19.4125
KTCTL-13 GDSC1 -0.4379 2.6663 -1.2063 23.2526
RXF 393L GDSC1 -0.1631 3.2193 -1.1829 21.7239
NCC021 GDSC1 0.0086 3.8084 -1.2969 21.684
A-704 GDSC1; GDSC2 0.0666 5.6962 -2.1651 22.1831
TK-10 GDSC1; GDSC2 0.1501 3.9797 -1.2463 16.809
786-O GDSC1; GDSC2; CTRP2 0.1994 7.2125 -0.6878 40.9291
BFTC-909 GDSC1; GDSC2; CTRP2 0.2466 10.2834 -1.7908 42.3607
SW156 GDSC1 0.3831 2.8924 -0.4992 14.2428
ACHN GDSC1; GDSC2; CTRP2 0.5562 9.4983 -1.5158 37.6891
NCC010 GDSC1 0.7711 4.2338 -0.8114 14.9954
LB996-RCC GDSC1; GDSC2 0.8109 4.5699 -0.9449 12.8187
769-P GDSC1; GDSC2; CTRP2 0.824 10.0039 -1.0693 39.2422
A-498 GDSC1; GDSC2 0.9751 8.9202 -2.9809 23.0262
SN12C GDSC1; GDSC2 0.993 7.108 -2.0598 18.6238
KMRC-1 GDSC1; GDSC2; CTRP2 1.172 11.2743 -1.685 35.9627
UO-31 GDSC1; CTRP2 1.3149 12.333 -1.5732 38.4504
Caki-1 GDSC1; CTRP2 3.2628 31.447 -9.0434 41.1397
SNU-1272 CTRP2 4.0568 18.8093 -2.0617 32.1055
VMRC-RCW GDSC1; CTRP2 4.4833 10.7734 2.2795 18.9473
KMRC-3 CTRP2 4.9439 24.0906 -3.9114 33.3087
VMRC-RCZ GDSC1; GDSC2; CTRP2 5.0282 17.852 -0.7263 27.1
KMRC-20 GDSC1; GDSC2; CTRP2 5.6558 18.1406 -0.3304 24.7724
OS-RC-2 GDSC1; GDSC2; CTRP2 6.0211 22.1037 -2.0047 27.9593
TUHR14TKB CTRP2 6.2201 10.5547 3.934 8.5315
TUHR10TKB CTRP2 6.3587 8.0284 5.3006 2.5699
Caki-2 CTRP2 6.7743 28.7094 -4.6858 31.2193
RCC10RGB GDSC1; GDSC2; CTRP2 7.4395 10.133 5.0125 2.2703
TUHR4TKB CTRP2 9.3568 21.5585 0.8444 14.891
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC1; GDSC2; CTRP2 -3.0036 5.1939 -3.6114 55.0479
MDST8 GDSC1; GDSC2; CTRP2 -2.0654 3.4456 -2.2557 50.5029
HCT 15 GDSC1; GDSC2; CTRP2 -1.5065 4.2425 -1.7833 47.3251
NCI-H508 GDSC1; GDSC2; CTRP2 -1.259 7.5191 -2.3726 46.5845
COLO201 CTRP2 -0.7906 4.8279 -1.1214 45.9907
DiFi GDSC1; GDSC2 -0.7626 3.0402 -1.7035 20.7991
NCI-H747 GDSC1; GDSC2; CTRP2 -0.7527 5.3688 -1.2005 43.1985
C2BBe1 GDSC1; GDSC2; CTRP2 -0.7306 9.851 -2.6505 44.7139
SNU-C1 GDSC1; GDSC2; CTRP2 -0.639 3.5404 -0.749 41.9174
SW948 GDSC1; GDSC2; CTRP2 -0.3799 6.6886 -1.1526 41.6095
LS123 GDSC1; GDSC2; CTRP2 -0.3263 10.1972 -2.3596 42.9916
CaR-1 GDSC1; GDSC2 -0.0277 6.2534 -2.5256 22.32
SW1417 GDSC1; GDSC2; CTRP2 0.0047 8.086 -1.1989 40.2378
HCC2998 GDSC1; GDSC2 0.0467 5.9022 -2.2848 20.9596
SNU-1033 CTRP2 0.2458 10.4531 -1.8617 42.4486
SK-CO-1 GDSC1; GDSC2; CTRP2 0.3758 9.8878 -1.4933 39.429
GP5d GDSC1; GDSC2 0.4462 5.2519 -1.6034 16.2914
KM12 GDSC1; GDSC2; CTRP2 0.4629 8.3263 -0.7931 37.876
HT115 GDSC1; GDSC2; CTRP2 0.4686 6.608 -0.2034 36.566
SNU-407 GDSC1; GDSC2; CTRP2 0.5472 6.5367 -0.0962 36.0346
SW48 GDSC1; GDSC2; CTRP2 0.5492 8.9993 -0.9564 37.9027
SNU-81 GDSC1; GDSC2; CTRP2 0.5576 8.6313 -0.8059 37.5797
COLO 320HSR GDSC1; GDSC2 0.5639 3.4701 -0.615 10.4755
LS513 GDSC1; GDSC2; CTRP2 0.8077 5.3209 0.5095 33.5353
LS180 GDSC1; GDSC2; CTRP2 0.8693 8.5948 -0.4589 35.8088
SNU-C2A CTRP2 0.9437 9.4656 -0.7231 38.1923
HT-55 GDSC1; GDSC2; CTRP2 1.1396 10.1233 -0.7888 35.6634
LS1034 GDSC1; GDSC2; CTRP2 1.1701 5.9787 0.7428 31.6941
SW626 GDSC1; GDSC2 1.187 5.29 -0.9913 11.9932
CL-11 GDSC1; GDSC2; CTRP2 1.471 8.4834 0.2259 32.2217
NCI-H716 GDSC1; GDSC2; CTRP2 1.4935 12.3025 -1.3788 35.7745
T84 GDSC1; GDSC2; CTRP2 1.5287 7.3297 0.7138 30.6719
SW837 GDSC1; GDSC2 1.742 5.966 -0.895 9.0256
SNU-175 GDSC2 1.9879 9.3352 -2.3757 16.0795
SNU-C2B GDSC1; GDSC2 2.0275 7.1273 -1.2552 10.3498
COLO205 GDSC1; GDSC2; CTRP2 2.1449 10.3379 0.1601 30.4254
SW620 GDSC1; GDSC2; CTRP2 2.3408 10.22 0.4127 29.1858
SW1463 GDSC1; GDSC2; CTRP2 2.5247 9.2158 1.0376 26.824
SW1116 GDSC1; GDSC2 2.5659 6.5354 -0.5968 5.7469
LS411N GDSC1; GDSC2; CTRP2 2.5872 11.4314 0.117 29.3323
GP2d CTRP2 2.6923 22.9192 -5.327 39.4593
CW-2 GDSC1; GDSC2; CTRP2 3.0645 10.2803 1.1212 25.1323
SNU-1040 GDSC2 3.1032 17.0301 -6.0878 22.7473
DLD-1 CTRP2 3.1388 12.6712 0.0807 29.5809
HCC-56 CTRP2 3.442 9.7188 1.7561 23.5245
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2 3.7114 11.8287 1.035 23.8039
CCK-81 GDSC1; GDSC2; CTRP2 4.3959 13.3836 0.9243 22.579
SNU-C5 GDSC1; GDSC2; CTRP2 4.7751 15.2914 0.3248 23.5628
RKO GDSC1; GDSC2; CTRP2 4.8073 16.9508 -0.4712 25.661
COLO 678 GDSC1; GDSC2; CTRP2 5.1584 14.4174 1.0984 20.4012
SNU-61 GDSC1; GDSC2; CTRP2 6.7329 11.9666 3.6357 8.8492
HCT 8 CTRP2 6.8157 11.5796 3.8903 7.6603
SNU-C4 CTRP2 7.2569 13.0585 3.4894 8.5758
OUMS-23 CTRP2 7.3082 14.3183 2.9076 10.8083
HCT 116 GDSC1; GDSC2; CTRP2 7.5354 9.0584 5.5248 0.4755
SNU-503 CTRP2 8.0794 37.936 -8.2388 33.5056
HT-29 GDSC1; GDSC2; CTRP2 8.1622 24.4553 -1.4612 22.0772
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 0.9287 6.2479 -1.6836 16.7948
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-878 CTRP2 -2.9292 -0.3401 -2.9303 59.7405
SNU-182 CTRP2 -2.2311 6.5119 -3.1188 53.7752
Li-7 CTRP2 -2.0559 4.0703 -2.3455 53.4587
SNU-886 CTRP2 -1.5822 3.69 -1.7742 54.0983
Hep-G2 CTRP2 -1.315 11.2483 -3.8287 49.441
JHH-1 GDSC1; GDSC2; CTRP2 -0.7372 2.1292 -1.2904 20.4753
SNU-423 GDSC1; GDSC2; CTRP2 -0.7343 5.1891 -1.1386 45.7294
Huh-7 GDSC1; GDSC2 -0.6144 3.9611 -1.9741 23.7422
PLC/PRF/5 CTRP2 -0.5156 11.0824 -2.9206 46.1579
HuH-1 GDSC1; GDSC2; CTRP2 -0.26 8.5173 -1.6402 44.1416
JHH-4 GDSC1; GDSC2; CTRP2 -0.211 6.6514 -1.1982 39.9997
HLE GDSC1; GDSC2 -0.185 6.6597 -2.8693 26.3639
HuH-6 CTRP2 -0.0349 10.685 -2.252 43.885
SNU-449 GDSC1; GDSC2; CTRP2 0.0689 4.3607 -0.1063 40.2793
SNU-761 CTRP2 0.0727 15.9665 -4.9623 43.5086
JHH-7 GDSC1; GDSC2 0.3374 4.602 -1.3792 16.9467
SK-HEP-1 GDSC1; GDSC2; CTRP2 0.5888 8.2503 -0.9557 36.3631
JHH-5 CTRP2 0.6668 24.5391 -7.994 45.3038
JHH-2 GDSC1; GDSC2; CTRP2 0.6787 17.0996 -4.4094 43.4251
Hep 3B2.1-7 GDSC1; CTRP2 0.6837 8.3 -0.5464 38.7879
SNU-398 GDSC1; GDSC2; CTRP2 0.8294 12.5318 -2.155 40.8246
Hep-G2/C3A GDSC1; GDSC2 1.4039 5.1106 -0.7292 9.7928
SNU-387 GDSC1; CTRP2 3.2596 15.3529 -1.0946 32.0774
JHH-6 GDSC1; GDSC2; CTRP2 6.5654 14.3291 2.3278 14.3569
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L51 CTRP2 -5.6783 13.9633 -9.8948 59.7744
LK2 CTRP2 -4.6905 5.8526 -5.6191 63.7707
DV-90 CTRP2 -3.4199 5.7142 -4.1959 59.2827
DMS 273 GDSC1; GDSC2; CTRP2 -3.3144 8.7433 -5.0154 57.2905
COR-L105 GDSC1; GDSC2; CTRP2 -3.2939 7.1412 -4.4662 57.986
NCI-H1734 CTRP2 -3.2587 2.1307 -3.3668 60.8208
RERF-LC-Ad2 CTRP2 -3.1746 12.0245 -6.1051 55.6288
NCI-H1395 CTRP2 -2.9228 11.6838 -5.7021 54.9657
NCI-H520 GDSC1; GDSC2; CTRP2 -2.8529 4.1938 -3.2301 57.6071
HCC44 GDSC1; GDSC2; CTRP2 -2.6743 5.7177 -3.3833 56.0752
NCI-H1184 CTRP2 -2.28 3.5001 -2.4933 54.8547
Lu-139 GDSC1; GDSC2 -2.1845 4.7588 -3.9168 38.3167
NCI-H1581 GDSC1; GDSC2; CTRP2 -2.1796 3.27 -2.3534 54.3408
NCI-H647 GDSC1; CTRP2 -2.1184 7.9553 -3.4504 52.9517
LXF 289 GDSC1; GDSC2; CTRP2 -1.8556 4.8542 -2.2838 52.2152
EPLC-272H GDSC1; GDSC2; CTRP2 -1.852 6.814 -2.7951 51.9297
A-549 GDSC1; GDSC2; CTRP2 -1.8295 3.4754 -2.0079 52.2461
Calu-3 GDSC1; GDSC2; CTRP2 -1.7556 5.94 -2.4397 51.5517
LK-2 GDSC1; GDSC2 -1.7352 2.8757 -2.6457 31.8471
NCI-H2373 GDSC1; GDSC2 -1.7027 3.2368 -2.7607 32.1746
SK-MES-1 GDSC1; GDSC2; CTRP2 -1.695 3.7773 -1.9083 51.4143
NCI-H2170 GDSC1; GDSC2; CTRP2 -1.6381 5.4532 -2.186 50.9712
NCI-H290 GDSC1 -1.5889 1.0475 -1.8384 33.8374
NCI-H720 GDSC1; GDSC2 -1.5759 4.3507 -3.1155 32.9675
LC-2/ad GDSC1 -1.5421 4.0821 -2.9611 38.2738
NCI-H1975 GDSC1; GDSC2; CTRP2 -1.5245 2.0304 -1.5543 50.4167
NCI-H2591 GDSC1; GDSC2 -1.5092 2.9561 -2.4412 29.874
EMC-BAC-2 GDSC1; GDSC2 -1.5055 3.06 -2.4807 30.0371
NCI-H2228 GDSC1; GDSC2; CTRP2 -1.465 8.0575 -3.0615 47.6357
NCI-H1341 GDSC1; GDSC2; CTRP2 -1.3631 3.1426 -1.4709 49.3826
NCI-H209 GDSC1; GDSC2 -1.3512 3.2834 -2.4151 29.0337
NCI-H1693 GDSC1; GDSC2; CTRP2 -1.2238 5.8372 -1.832 48.7005
HCC4006 CTRP2 -1.1922 5.1718 -1.6331 48.4609
SBC-1 GDSC1 -1.1906 4.4484 -2.7719 35.5914
NCI-H1648 GDSC1; GDSC2 -1.1732 3.3434 -2.2577 27.4986
NCI-H2196 CTRP2 -1.1297 11.7393 -3.8369 48.7537
NCI-H1623 GDSC1; GDSC2; CTRP2 -1.1086 7.202 -2.1062 48.2219
COLO 699 CTRP2 -1.049 11.7324 -3.7495 48.4416
NCI-H2795 GDSC1; GDSC2 -0.9744 3.4657 -2.1085 25.9068
IST-SL2 GDSC1 -0.9566 1.927 -1.4446 27.6262
NCI-H838 GDSC1; CTRP2 -0.9522 14.7001 -4.9346 48.3645
SCLC-21H CTRP2 -0.7647 19.9235 -7.6566 46.9667
Lu-99A GDSC1; GDSC2 -0.7412 4.848 -2.5154 26.9095
COR-L47 CTRP2 -0.7148 16.8469 -6.1461 46.3408
NCI-H1703 GDSC1; GDSC2; CTRP2 -0.7145 6.9385 -1.594 46.067
NCI-H2023 GDSC1; GDSC2; CTRP2 -0.6864 8.1333 -1.9616 46.2251
NCI-H1437 GDSC1 -0.6606 2.227 -1.2494 24.7151
ChaGo-K-1 GDSC1; CTRP2 -0.6017 12.3296 -3.5366 46.7805
NCI-H1944 GDSC1; GDSC2; CTRP2 -0.5948 7.3721 -1.6028 45.5324
NCI-H524 GDSC1; GDSC2 -0.5713 4.8452 -2.3497 25.4587
NCI-H2122 GDSC1; GDSC2; CTRP2 -0.5688 5.6435 -1.0674 44.8498
SK-LU-1 GDSC1; CTRP2 -0.5504 11.2102 -3.0101 46.3361
NCI-H1876 GDSC1; GDSC2 -0.5458 3.7065 -1.7878 22.4782
COR-L279 GDSC1; GDSC2; CTRP2 -0.5424 10.427 -3.0521 43.8978
NCI-H1048 GDSC1; GDSC2 -0.5335 3.2269 -1.555 21.1437
EBC-1 GDSC1; GDSC2; CTRP2 -0.4213 6.5123 -1.145 44.2666
Lu-65 GDSC1; GDSC2; CTRP2 -0.4139 9.0182 -2.3251 42.6154
LC-1/sq-SF CTRP2 -0.3995 17.9001 -5.8436 47.0172
NCI-H510A GDSC1 -0.3709 4.7967 -2.1343 28.4722
NCI-H3122 GDSC1; GDSC2 -0.3499 4.6451 -2.0414 23.0669
NCI-H1792 GDSC1; GDSC2; CTRP2 -0.345 8.0414 -1.5604 44.4095
PC-14 GDSC1; GDSC2; CTRP2 -0.2974 5.685 -0.972 39.8954
NCI-H1355 GDSC1; GDSC2; CTRP2 -0.2856 16.4618 -5.0634 46.4352
RERF-LC-KJ GDSC1; GDSC2 -0.2235 4.5515 -1.8758 21.7208
NCI-H513 GDSC1; GDSC2 -0.2193 4.1158 -1.6624 20.5383
SBC-3 GDSC1; GDSC2 -0.2001 3.0001 -1.1175 17.3242
NCI-H2369 GDSC1; GDSC2 -0.1994 2.4336 -0.8598 15.7924
NCI-H1666 GDSC1; GDSC2; CTRP2 -0.1909 6.6229 -0.9267 42.9516
DMS 114 GDSC1; GDSC2; CTRP2 -0.1366 8.2399 -1.4064 43.3692
NCI-H1155 GDSC1; GDSC2; CTRP2 -0.124 4.0782 -0.2703 41.4671
A-427 GDSC1 -0.1235 3.9789 -1.505 23.6602
NCI-H2227 GDSC1 -0.1162 4.8599 -1.9241 26.1263
NCI-H2731 GDSC1; GDSC2 -0.0888 5.1906 -2.0598 22.1973
NCI-H1793 GDSC1; GDSC2; CTRP2 -0.069 15.5546 -4.4299 45.5266
EMC-BAC-1 GDSC1 -0.0353 4.3886 -1.6191 23.9589
RERF-LC-Sq1 GDSC1; GDSC2 -0.0151 6.1229 -2.4498 23.8686
NCI-H1339 CTRP2 0.0052 18.0437 -5.5128 45.8321
NCI-H847 GDSC1; GDSC2 0.0099 3.5473 -1.1701 16.8569
CAL-12T GDSC1; CTRP2 0.0348 9.7376 -1.7934 43.1503
Lu-99 CTRP2 0.0677 11.2278 -2.3719 43.6303
CPC-N GDSC1; GDSC2 0.095 4.385 -1.4954 18.4553
NCI-H3255 GDSC1 0.1172 2.639 -0.6356 16.4691
NCI-H211 GDSC1; GDSC2; CTRP2 0.1287 9.6038 -1.6407 42.615
NCI-H292 GDSC1; CTRP2 0.1406 10.8797 -2.1494 43.1483
NCI-H69 GDSC1; GDSC2; CTRP2 0.1597 7.9748 -0.992 41.5954
IA-LM GDSC1; GDSC2; CTRP2 0.181 6.6797 -0.5386 40.7306
NCI-H2171 CTRP2 0.2084 7.9943 -0.9465 41.3299
NCI-H2444 GDSC1; CTRP2 0.2493 8.0881 -1.2482 38.2723
NCI-H187 GDSC1 0.2807 2.955 -0.6267 15.6577
NCI-H661 GDSC1; GDSC2; CTRP2 0.3336 10.7016 -1.8731 42.1474
COR-L23 GDSC1; GDSC2 0.3366 3.228 -0.7058 12.8859
NCI-H841 GDSC1; GDSC2; CTRP2 0.3406 5.9018 -0.3464 35.7406
NCI-H2810 GDSC1 0.3621 9.9752 -4.0297 32.7168
NCI-H2347 GDSC1; GDSC2 0.3645 8.4778 -3.2808 26.1605
T3M-10 CTRP2 0.3727 10.9167 -1.9227 42.0689
NCI-H1568 GDSC1; GDSC2; CTRP2 0.3875 7.6979 -0.6484 40.111
NCI-H810 GDSC1; GDSC2; CTRP2 0.4349 9.6096 -1.3187 41.0376
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 0.46 8.0947 -0.7114 39.946
NCI-H446 GDSC1; GDSC2; CTRP2 0.4957 9.9638 -1.3979 40.9322
NCI-H358 GDSC1; GDSC2; CTRP2 0.5358 8.004 -0.5969 39.4425
NCI-H2081 GDSC1; CTRP2 0.5734 5.3285 0.0846 33.5681
HCC1588 CTRP2 0.5772 6.4963 -0.0514 38.1272
NCI-H23 GDSC1; GDSC2; CTRP2 0.5807 7.6932 -0.7397 35.8703
LCLC-97TM1 GDSC1; GDSC2; CTRP2 0.6281 9.5362 -1.0849 39.9667
Lu-134-A GDSC1 0.6354 5.7785 -1.6995 21.5483
NCI-H596 GDSC1; GDSC2 0.6373 8.44 -3.0264 24.2584
NCI-H2110 GDSC1; CTRP2 0.7148 10.6032 -1.4339 40.2102
NCI-H146 GDSC1; CTRP2 0.8671 7.3709 -0.0165 36.955
HCC15 GDSC1; GDSC2; CTRP2 0.8772 8.4659 -0.4014 37.7817
SW1573 GDSC1; GDSC2 0.8912 5.3137 -1.2482 14.4032
NCI-H1688 GDSC1; GDSC2 0.9017 6.7423 -1.9535 18.3438
NCI-H2818 GDSC1; GDSC2 0.9584 4.3749 -0.7223 10.9997
SW1271 GDSC1; GDSC2; CTRP2 0.9663 9.4762 -1.0839 35.3324
DMS 79 GDSC1 0.9729 3.9147 -0.48 11.727
COR-L88 GDSC1; GDSC2; CTRP2 0.9895 11.3779 -1.9148 36.9972
NCI-H2869 GDSC1 1.0003 4.6664 -0.833 14.2832
NCI-H2405 GDSC1; GDSC2; CTRP2 1.0563 7.3265 0.2036 35.7244
DMS 53 GDSC1; GDSC2; CTRP2 1.0761 6.411 0.518 34.8085
RERF-LC-MS GDSC1; CTRP2 1.0861 7.1065 0.0274 31.9011
HCC827 GDSC1; GDSC2; CTRP2 1.088 7.3959 0.2141 35.5838
NCI-H2595 GDSC1; GDSC2 1.0943 4.1854 -0.5148 9.3089
NCI-H1781 GDSC1; GDSC2 1.1381 2.7638 0.2304 4.4856
NCI-H2461 GDSC1; GDSC2 1.1719 3.8521 -0.2855 7.6497
LB647-SCLC GDSC1 1.2038 3.8488 -0.2583 9.1932
COR-L321 GDSC1 1.2061 5.5189 -1.0901 15.3799
NCI-H522 GDSC1; GDSC2; CTRP2 1.214 11.1951 -1.1713 38.0987
UMC-11 GDSC1; GDSC2 1.2152 9.0422 -2.8432 21.7199
PaCa-3 GDSC1; GDSC2 1.2276 4.8943 -0.7609 10.4679
NCI-H1869 GDSC1; CTRP2 1.2705 17.508 -4.0281 41.5555
LC-1/sq GDSC1; GDSC2 1.3027 4.015 -0.2632 7.1574
NCI-H2722 GDSC1; GDSC2 1.3304 3.7009 -0.086 5.9724
NCI-H82 GDSC1; GDSC2 1.3308 6.1665 -1.313 13.5069
Lu-135 GDSC1; GDSC2 1.3399 4.1531 -0.303 7.3091
HCC78 GDSC1; GDSC2; CTRP2 1.4788 10.1559 -0.4493 35.8102
NCI-H2085 GDSC1; GDSC2; CTRP2 1.4872 9.8368 -0.3056 35.4627
VMRC-LCD GDSC1; GDSC2; CTRP2 1.4882 10.8251 -0.7278 36.3667
NCI-H64 GDSC1; GDSC2 1.5037 4.8594 -0.5277 8.2874
COR-L311 GDSC2 1.561 6.3379 -1.2171 12.3175
Ms-1 GDSC1; GDSC2 1.6004 4.7131 -0.3831 7.1503
NCI-H1993 GDSC1; GDSC2 1.624 4.8993 -0.4572 7.5509
NCI-H526 GDSC1; GDSC2; CTRP2 1.6957 9.4647 0.0679 33.885
NCI-H345 GDSC1 1.7217 6.3286 -1.0894 13.6361
NCI-H2141 GDSC1; GDSC2; CTRP2 1.7572 5.7358 1.2468 25.3777
IST-SL1 GDSC1 1.7646 5.5377 -0.6675 10.4977
HCC2279 CTRP2 1.786 19.5456 -4.5165 40.7233
NCI-H322M GDSC1; GDSC2 1.7976 8.1358 -1.9269 15.6532
NCI-H322 CTRP2 1.8058 11.8363 -0.8528 35.6206
ABC-1 GDSC1 1.8275 4.6819 -0.2052 6.8754
NCI-H1436 GDSC1 1.9066 5.4701 -0.5319 9.0838
LUDLU-1 CTRP2 1.9407 12.0635 -0.82 35.1432
NCI-H2066 GDSC1; GDSC2 1.9571 5.7493 -0.632 7.8292
Calu-6 GDSC1; GDSC2; CTRP2 2.0195 10.6907 -0.1237 33.3342
COLO 668 GDSC1; GDSC2; CTRP2 2.0335 10.93 -0.2155 33.5134
NCI-H1385 CTRP2 2.1318 8.2542 1.0185 29.8002
NCI-H1836 GDSC1 2.1878 4.3088 0.1993 3.0916
NCI-H1573 GDSC1; GDSC2; CTRP2 2.2109 11.3301 -0.215 32.974
NCI-H835 GDSC1; GDSC2 2.2819 8.3388 -1.6637 13.0201
NCI-H2804 GDSC1 2.2897 14.8801 -4.8968 29.1208
Lu-165 GDSC1; GDSC2 2.32 6.2519 -0.624 6.9859
NCI-H1963 GDSC2 2.3432 4.6268 0.1459 2.5302
NCI-H2029 GDSC1; CTRP2 2.389 13.0977 -0.8526 33.8987
HCC1833 CTRP2 2.4068 18.2171 -3.2874 37.8863
NCI-H1915 GDSC1; GDSC2; CTRP2 2.4119 13.0822 -0.8229 33.7704
NCI-H1373 CTRP2 2.4481 15.6473 -2.0063 35.9084
NCI-H1299 GDSC1; GDSC2; CTRP2 2.451 10.4651 0.4167 30.6094
NCI-H2286 CTRP2 2.4936 23.7954 -5.9399 40.3984
HOP-62 GDSC1; GDSC2; CTRP2 2.5074 10.0971 0.6374 29.8099
NCI-H1755 GDSC1; GDSC2; CTRP2 2.5253 13.6342 -0.9719 33.767
NCI-H1770 GDSC1 2.5415 10.3112 -2.4417 19.166
NCI-H1105 GDSC1; CTRP2 2.7381 13.4826 -0.6932 32.5755
NCI-H727 GDSC1; GDSC2; CTRP2 2.7714 10.1733 0.8728 28.3306
NCI-H1435 GDSC1; CTRP2 2.9484 8.8754 1.6226 25.3638
NCI-H1304 GDSC1 2.9663 4.5744 0.4682 0.6028
NCI-H1092 GDSC1; GDSC2; CTRP2 3.0129 12.005 0.2724 29.403
COR-L95 GDSC1; GDSC2; CTRP2 3.0576 9.3018 1.5509 25.3015
Sq-1 CTRP2 3.0583 8.3082 1.9758 23.8013
NCI-H1694 GDSC1; GDSC2; CTRP2 3.1891 10.7727 1.0204 26.6935
NCI-H1838 GDSC1; GDSC2; CTRP2 3.2023 11.6246 0.6368 27.8384
NCI-H2135 GDSC1 3.2214 4.759 0.5005 0.3583
HCC95 CTRP2 3.2637 14.1936 -0.5291 30.7907
NCI-H2342 GDSC1; GDSC2; CTRP2 3.3526 15.0446 -1.4272 29.2645
HCC366 GDSC1; CTRP2 3.3646 9.6246 1.7205 23.8603
NCI-H650 GDSC1; GDSC2; CTRP2 3.3833 13.7828 -0.2173 29.7114
MOR/CPR CTRP2 3.671 13.2707 0.3029 27.5715
NCI-H2172 GDSC1; CTRP2 3.6819 16.7049 -1.3634 31.6013
NCI-H889 CTRP2 3.7184 17.9019 -1.9192 32.6104
NCI-H2009 GDSC1; GDSC2; CTRP2 3.879 12.8684 0.6942 25.8941
NCI-H2291 GDSC1; CTRP2 3.9139 16.9039 -1.2491 30.8096
HCC2108 CTRP2 3.9188 15.893 -0.7469 29.6702
EKVX GDSC1; CTRP2 3.9927 13.0875 0.6948 25.6078
NCI-H1563 GDSC1; GDSC2; CTRP2 4.0093 16.7929 -1.1077 30.2779
NCI-H2030 GDSC1; CTRP2 4.0758 16.1595 -0.7348 29.2674
NCI-H226 GDSC1; GDSC2; CTRP2 4.091 15.9152 -1.2046 26.9247
HCC2935 CTRP2 4.1832 12.8858 0.9711 24.2743
DMS 454 CTRP2 4.1959 11.6001 1.6077 22.1052
RERF-LC-A1 CTRP2 4.2136 20.0478 -2.536 32.6126
SHP-77 GDSC1; GDSC2; CTRP2 4.2495 10.027 2.413 19.0077
NCI-H2106 CTRP2 4.291 14.708 0.1767 26.3995
RERF-LC-Ad1 CTRP2 4.4317 12.605 1.3392 22.4604
HOP-92 GDSC1; GDSC2; CTRP2 4.5967 13.2215 1.1879 22.578
LOU-NH91 GDSC1; GDSC2; CTRP2 4.6705 12.2554 1.7308 20.5316
NCI-H196 GDSC1; GDSC2; CTRP2 5.062 18.858 -1.1984 28.1396
NCI-H1650 GDSC1; GDSC2; CTRP2 5.0813 15.4116 0.5358 23.5429
NCI-H2087 GDSC1; GDSC2; CTRP2 5.1271 15.1607 0.7009 22.9372
NCI-H2126 CTRP2 5.3442 15.9585 0.4924 23.1023
NCI-H1651 GDSC1; GDSC2; CTRP2 5.3732 16.5916 0.2015 23.8952
HCC1171 CTRP2 5.8321 17.5473 0.1151 23.1882
KNS-62 GDSC1; GDSC2; CTRP2 6.1965 19.3026 -0.4584 24.0302
SBC-5 GDSC1; GDSC2; CTRP2 6.3833 13.8736 2.4085 14.391
HCC1438 CTRP2 6.6274 14.2023 2.4405 13.8119
BEN GDSC1; CTRP2 6.7137 18.7651 0.2329 21.1289
NCI-H460 GDSC1; CTRP2 6.9948 17.5086 1.0838 17.9726
NCI-H441 GDSC1; GDSC2; CTRP2 7.3601 19.976 0.1424 20.2174
Calu-1 CTRP2 7.6346 13.4992 3.5447 7.7705
HCC1195 CTRP2 8.404 36.1916 -7.1107 31.8886
LCLC-103H GDSC1; GDSC2; CTRP2 9.9002 20.8275 1.5665 11.8136
Hs 888.Lu CTRP2 -5.0268 11.0061 -7.6806 61.0728
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 -0.2726 3.5265 -1.4344 19.4481
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 -3.808 11.9047 -6.728 57.476
SYO-1 CTRP2 0.9118 13.2316 -2.3862 40.8516
P-STS CTRP2 1.3731 11.627 -1.1984 37.6327
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -2.8608 11.9573 -5.7466 54.701
COV644 CTRP2 -6.2468 15.2067 -11.0126 60.38
A2780 GDSC1; GDSC2; CTRP2 -3.7156 8.4779 -5.3585 58.77
OVK18 GDSC1; CTRP2 -3.2415 4.7892 -3.7764 59.0929
MCAS CTRP2 -2.8504 2.5347 -2.9771 58.3917
COV434 CTRP2 -2.4263 9.187 -4.215 53.9217
JHOM-1 CTRP2 -2.299 10.9051 -4.7314 53.0917
IGROV-1 GDSC1; GDSC2; CTRP2 -1.9292 6.3616 -2.746 52.3684
SNU-840 CTRP2 -1.6465 21.0189 -8.5297 50.4313
OVTOKO GDSC1; GDSC2; CTRP2 -1.2346 4.712 -1.5793 48.6709
SNU-8 CTRP2 -1.1458 4.3718 -1.4173 48.1039
DOV13 GDSC1; GDSC2; CTRP2 -0.88 3.7608 -1.0335 46.3493
TYK-nu GDSC1; GDSC2; CTRP2 -0.811 7.5321 -1.8904 46.7283
TOV-112D GDSC1; GDSC2; CTRP2 -0.8106 6.2198 -1.4853 46.43
EFO-27 GDSC1; CTRP2 -0.7717 18.723 -6.5947 48.1673
TOV-21G GDSC1; GDSC2 -0.6443 3.6978 -1.8816 23.3732
OV-90 GDSC1; GDSC2; CTRP2 -0.5283 4.6674 -0.9386 40.8341
OV7 CTRP2 -0.194 11.831 -2.9004 44.9918
ES-2 GDSC1; GDSC2 -0.1883 2.9524 -1.0838 17.0795
OAW28 GDSC1; GDSC2; CTRP2 0.2885 8.147 -0.915 40.9632
OVCAR-3 GDSC1; GDSC2 0.3885 6.5155 -2.2826 21.6715
OVCAR-4 GDSC1; GDSC2; CTRP2 0.4574 8.4064 -0.8287 40.1652
JHOS-2 GDSC1; CTRP2 0.4994 10.4283 -1.5855 41.1853
COV362 CTRP2 1.178 15.5826 -3.207 40.9984
JHOS-4 GDSC1 1.439 4.7629 -0.5293 10.4903
OVSAHO CTRP2 1.4461 15.6817 -2.9912 40.0116
SK-OV-3 GDSC1; GDSC2; CTRP2 1.5728 12.649 -1.4562 37.4596
OVCAR-8 GDSC1; GDSC2; CTRP2 1.6041 7.9549 0.5695 32.8442
Caov-4 GDSC1; GDSC2 1.7919 4.5716 -0.1767 5.4361
OV56 GDSC1; GDSC2; CTRP2 1.9807 9.0338 0.5452 31.6898
OVKATE GDSC1; GDSC2 1.984 6.5089 -0.9837 9.8707
OAW42 GDSC1; GDSC2; CTRP2 2.021 15.7687 -2.4746 37.7715
HEY A8 CTRP2 2.2464 14.7645 -1.7786 36.0664
SNU-119 CTRP2 2.5415 13.7688 -1.0198 33.8214
Caov-3 CTRP2 2.6706 11.5805 0.1316 30.7469
EFO-21 GDSC1; GDSC2; CTRP2 2.8052 11.0263 0.5207 29.2836
ONCO-DG-1 CTRP2 3.2402 17.1989 -2.0131 33.9172
OC 314 GDSC1; GDSC2; CTRP2 3.4135 10.3619 1.4334 24.7233
FU-OV-1 GDSC1; GDSC2; CTRP2 3.5899 9.9424 1.8024 22.9636
Kuramochi GDSC1; GDSC2; CTRP2 3.5995 12.0934 0.8008 26.2832
OVCAR-5 GDSC1; GDSC2; CTRP2 3.7453 16.1914 -1.0528 30.7847
JHOC-5 CTRP2 5.1569 14.4959 1.058 21.735
ES2 CTRP2 5.2643 17.2245 -0.2084 25.2653
RMG-I GDSC1; GDSC2; CTRP2 5.4696 22.2818 -2.5581 30.0895
OVISE GDSC1; GDSC2; CTRP2 8.2372 27.5486 -2.9394 26.0008
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -2.4505 7.5664 -3.6825 54.4532
Yamato-SS CTRP2 -1.9022 10.8024 -4.2697 51.6788
TE 441.T CTRP2 -4.5689 5.3152 -5.3475 63.8413
TE 617.T CTRP2 -4.4692 6.9093 -5.6767 62.2099
Rh41 GDSC1; GDSC2; CTRP2 -4.197 -1.4335 -4.1978 68.0455
G-402 GDSC1; GDSC2; CTRP2 -3.9249 4.0195 -4.357 62.5619
G-401 GDSC1; GDSC2; CTRP2 -2.6342 7.3725 -3.8202 55.2787
A-204 GDSC1; GDSC2; CTRP2 -2.133 7.2639 -3.2404 53.1552
VA-ES-BJ GDSC1; GDSC2 -1.573 2.1341 -2.1826 28.9431
Tm87-16 CTRP2 -1.4867 10.5451 -3.7271 50.1031
Hs 633.T GDSC1; GDSC2 -1.3849 2.2134 -2.0116 27.2164
TTC-709 CTRP2 -1.2892 10.4196 -3.4679 49.3064
MES-SA GDSC1; GDSC2; CTRP2 -0.9418 8.7798 -2.4694 47.6157
MFH-ino GDSC1; GDSC2 -0.8618 4.0585 -2.2645 26.2112
STS-0421 GDSC1 -0.7231 3.386 -1.8182 28.5698
SK-LMS-1 GDSC1; GDSC2; CTRP2 -0.1379 9.6382 -1.9372 43.9638
HT-1080 GDSC1; GDSC2; CTRP2 -0.0581 7.4529 -1.0471 42.5651
RD GDSC1; GDSC2; CTRP2 -0.045 7.3958 -1.2915 39.5065
SW982 GDSC1; GDSC2; CTRP2 -0.0107 8.2302 -1.2673 42.6792
SW872 GDSC1; GDSC2 0.2761 4.6326 -1.45 17.5659
EW-8 GDSC1; GDSC2 0.3192 3.775 -0.9889 14.6796
KYM-1 GDSC1; GDSC2; CTRP2 0.5402 9.4028 -1.1246 40.3515
SW684 GDSC1; GDSC2 0.5493 7.5762 -2.6708 22.9881
Rh30 GDSC1; GDSC2 0.6795 7.9196 -2.7304 22.8418
Rh18 GDSC1; CTRP2 0.7369 9.326 -0.8856 39.2307
Hs 729.T CTRP2 0.882 14.4523 -2.974 41.6053
RKN GDSC1; GDSC2; CTRP2 1.1837 8.0346 0.0888 35.5621
BT-16 CTRP2 1.4662 12.2976 -1.4042 37.6987
SK-UT-1 GDSC2; CTRP2 2.3185 19.987 -4.8046 37.7189
GCT GDSC1; GDSC2; CTRP2 3.2058 12.6068 0.176 29.143
BT-12 CTRP2 9.2667 19.8018 1.6307 12.473
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 0.616 25.1291 -8.3287 45.5258
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC1; GDSC2; CTRP2 -1.0055 5.9541 -1.8271 44.5427
MSTO-211H GDSC1; GDSC2; CTRP2 -0.7628 5.8742 -1.3387 46.0711
MPP 89 GDSC1; GDSC2; CTRP2 -0.6537 5.3291 -1.0833 45.2738
JL-1 CTRP2 -0.4101 36.6071 -14.9009 48.4667
NCI-H2052 GDSC1; GDSC2; CTRP2 0.6868 8.9377 -0.7859 39.2325
NCI-H28 GDSC1; GDSC2; CTRP2 1.8083 10.8185 -0.3962 34.6337
IST-Mes1 GDSC1; GDSC2; CTRP2 1.9996 15.1627 -2.2069 37.4344
ACC-MESO-1 CTRP2 3.7903 17.2308 -1.5229 31.6708
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP2 -5.8625 37.8057 -20.5947 55.4507
LNCaP clone FGC GDSC1; GDSC2; CTRP2 -3.5859 1.5224 -3.6587 62.9425
22Rv1 GDSC1; GDSC2; CTRP2 -1.4236 5.6301 -1.9964 49.7966
PC-3 GDSC1; GDSC2 -1.1904 4.3944 -2.747 29.7985
VCaP GDSC1; GDSC2; CTRP2 2.1314 8.6698 0.8524 30.3134
DU145 GDSC1; GDSC2; CTRP2 2.9732 14.313 -0.8634 32.3195
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -0.5634 7.2255 -1.5209 45.3165
A-253 GDSC1; GDSC2; CTRP2 2.1555 10.6233 0.0451 32.4945
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -2.6057 2.4457 -3.4067 46.5479
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-StC-K140 CTRP2 -9.7096 21.1049 -16.7358 63.9893
HGC-27 GDSC1; GDSC2; CTRP2 -5.1872 5.4324 -6.0515 65.7019
GSS CTRP2 -2.6896 1.6206 -2.7348 57.8163
HSC-39 GDSC1; GDSC2 -2.3523 -0.7079 -2.3691 33.7239
RF-48 GDSC1; GDSC2 -2.1191 4.1623 -3.5881 37.1043
Fu97 GDSC1; GDSC2; CTRP2 -2.0674 4.8229 -2.5071 53.362
NUGC-3 GDSC1; GDSC2; CTRP2 -1.5143 5.0855 -1.9639 50.3026
SNU-5 GDSC1; GDSC2; CTRP2 -1.3406 4.9903 -1.7537 49.3101
ECC10 GDSC1; GDSC2; CTRP2 -1.3242 3.996 -1.5447 49.1689
GCIY GDSC1; GDSC2 -1.2172 2.0699 -1.7775 25.2384
HuG1-N CTRP2 -1.0568 23.8317 -9.2896 49.1399
NCI-N87 GDSC1; CTRP2 -0.9576 6.9803 -1.8718 47.3962
TMK-1 GDSC1 -0.8908 2.2325 -1.4943 27.5645
SNU-668 CTRP2 -0.6234 12.1424 -3.479 46.8303
SNU-16 GDSC1; GDSC2; CTRP2 -0.5564 3.1519 -0.6226 44.1212
IM95 GDSC1; GDSC2; CTRP2 -0.4007 12.0409 -3.6164 43.9015
SK-GT-2 GDSC1; GDSC2 -0.3757 4.1132 -1.812 21.9496
SNU-1 GDSC1; GDSC2; CTRP2 -0.3535 3.9976 -0.5041 42.9657
LMSU CTRP2 -0.3524 16.7976 -5.2849 46.7049
SCH GDSC1 -0.015 4.3239 -1.5686 23.5516
23132/87 GDSC1; GDSC2; CTRP2 0.0343 8.2551 -1.2279 42.4444
OCUM-1 GDSC1; GDSC2; CTRP2 0.0508 13.7334 -3.4833 44.5924
RERF-GC-1B GDSC2 0.3653 7.9144 -2.9994 25.0213
SNU-620 CTRP2 0.4361 7.1996 -0.4265 39.4926
Hs 746.T GDSC1; GDSC2; CTRP2 0.9102 7.3521 0.0366 36.6695
TGBC11TKB GDSC1; GDSC2 1.1261 5.2283 -1.01 12.2802
MKN28 GDSC1; GDSC2 1.379 6.4096 -1.3958 13.853
MKN7 GDSC1; CTRP2 1.4661 13.4842 -1.9458 38.566
KATO III GDSC1; GDSC2; CTRP2 1.4875 10.0317 -0.3875 35.6458
SNU-216 CTRP2 1.7748 8.292 0.6238 32.1268
SNU-601 CTRP2 1.8467 12.4958 -1.1117 36.0065
SH-10-TC CTRP2 1.9839 12.5412 -0.9953 35.3694
KE-39 CTRP2 2.0183 12.0316 -0.7275 34.7157
MKN1 GDSC1; GDSC2; CTRP2 2.1165 8.1905 1.0271 29.8222
MKN74 CTRP2 2.5554 16.4077 -2.2703 36.0594
NUGC-4 GDSC1; GDSC2; CTRP2 3.3314 10.749 1.1728 25.8139
ECC12 CTRP2 3.8651 15.2281 -0.4698 29.1318
SNU-719 CTRP2 3.8673 14.7428 -0.23 28.5209
AGS GDSC1; GDSC2; CTRP2 4.2945 15.5184 -0.2198 27.467
GSU CTRP2 6.1509 7.2118 5.5469 1.8946
MKN45 GDSC2; CTRP2 12.4183 31.4517 -1.8203 17.8985
SNU-685 CTRP2 -0.6327 17.6439 -5.9551 47.6692
SNG-M GDSC1; GDSC2; CTRP2 1.6788 8.7919 0.3249 33.2719
SNU-1077 CTRP2 5.129 13.8393 1.3601 20.787
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -5.2943 11.6457 -8.2095 61.3483
K5 GDSC2 -3.0965 0.7942 -3.4162 42.1507
FTC-238 CTRP2 -2.8403 10.3995 -5.1116 55.0678
IHH-4 GDSC1; GDSC2 -1.5401 2.7361 -2.3833 29.7499
KMH-2 GDSC1 -0.6239 3.4935 -1.7674 27.7522
ML-1 [Human leukemia] GDSC1; CTRP2 -0.5547 8.7811 -2.3768 43.2354
8305C GDSC1; GDSC2; CTRP2 -0.4547 5.6237 -0.9379 44.1469
CAL-62 GDSC1; GDSC2; CTRP2 0.3083 7.5042 -0.6673 40.4568
BHT-101 GDSC1; GDSC2; CTRP2 0.3115 6.6116 -0.3757 39.8823
HTC-C3 GDSC1; GDSC2 0.342 4.5699 -1.3592 16.8143
WRO GDSC1; GDSC2 0.3631 4.8437 -1.4754 17.4183
B-CPAP GDSC1; GDSC2; CTRP2 0.6419 9.409 -1.0194 39.8072
ASH-3 GDSC1; GDSC2 0.6689 4.577 -1.0714 14.0315
TT2609-C02 GDSC1; GDSC2; CTRP2 0.8762 10.2783 -1.1289 39.162
CGTH-W-1 GDSC1; GDSC2; CTRP2 1.4951 10.27 -0.481 35.8258
8505C GDSC1; GDSC2; CTRP2 2.0017 11.6131 -0.5542 34.3899
TT GDSC1; GDSC2; CTRP2 2.2085 13.1979 -1.0771 34.8766
FTC-133 GDSC1; GDSC2; CTRP2 3.1495 13.5301 -0.3189 30.5805
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 31 CTRP2 -3.3048 12.0536 -6.2544 56.0008
BICR 18 CTRP2 -2.9152 3.5972 -3.1904 58.2175
YD-10B CTRP2 -2.8343 3.8778 -3.1513 57.6687
KON GDSC1 -2.1767 1.4661 -2.6045 41.4542
SCC-25 GDSC1; CTRP2 -2.1585 6.5568 -3.0527 53.427
DOK GDSC1; GDSC2 -1.8679 2.7741 -2.745 32.9095
PCI-06A GDSC1 -1.6591 2.3436 -2.3543 36.8134
PE/CA-PJ34 (clone C12) CTRP2 -1.379 17.9538 -6.8404 49.781
HO-1-N-1 GDSC1; GDSC2 -1.2968 3.1628 -2.3071 28.2818
PCI-04B GDSC1 -1.2683 1.936 -1.782 31.4909
JHU-011 GDSC1 -1.2106 2.9203 -2.1143 32.8966
BICR 10 GDSC1; GDSC2 -1.1882 3.1208 -2.1766 27.167
BICR 6 CTRP2 -1.1361 23.5786 -9.245 49.3043
PE/CA-PJ15 GDSC1; CTRP2 -0.9563 8.8664 -2.5169 47.6976
YD-8 CTRP2 -0.8363 10.6161 -3.0672 47.4359
SNU-899 CTRP2 -0.8154 5.9391 -1.4134 46.3935
PCI-15A GDSC1 -0.7864 6.3247 -3.2662 35.1929
JHU-029 GDSC1 -0.7492 3.1067 -1.7193 28.1419
PE/CA-PJ49 CTRP2 -0.6866 15.9475 -5.2286 47.636
JHU-022 GDSC1; GDSC2 -0.5767 3.1307 -1.5549 21.3152
OSC-20 GDSC1; GDSC2 -0.431 3.0455 -1.3694 19.6848
Detroit 562 GDSC1; GDSC2; CTRP2 -0.3448 7.1303 -1.2525 44.0599
SAT [Human HNSCC] GDSC1; GDSC2 -0.3298 4.7248 -2.0606 23.0906
Ca9-22 GDSC1; GDSC2 -0.3295 3.0623 -1.2752 18.745
SCC-15 GDSC1; GDSC2 -0.313 6.4065 -2.8626 26.8005
BICR 22 GDSC1; GDSC2; CTRP2 -0.1559 9.529 -1.9134 44.0095
HO-1-u-1 GDSC1; GDSC2 -0.1068 4.7566 -1.865 21.2342
SAS GDSC1; GDSC2 -0.0498 3.4673 -1.1895 17.1891
PCI-38 GDSC1 -0.0166 8.9453 -3.8487 33.6292
SNU-1076 CTRP2 0.0767 8.6749 -1.3372 42.4252
PCI-30 GDSC1; GDSC2 0.0961 4.3429 -1.4738 18.3278
KOSC-2 GDSC1 0.1856 4.2894 -1.3645 21.3306
BB30-HNC GDSC1 0.2363 3.8963 -1.1252 19.4792
OSC-19 GDSC1 0.3492 4.8627 -1.4974 21.4793
BB49-HNC GDSC1 0.3974 5.4322 -1.7364 22.7538
PE/CA-PJ41 (clone D2) CTRP2 0.4043 11.2719 -2.0408 42.0995
HSC-3 GDSC1; GDSC2; CTRP2 0.4855 8.7684 -0.9352 40.2422
SNU-1214 CTRP2 0.5125 7.3101 -0.3804 39.1014
SCC-9 GDSC1; GDSC2; CTRP2 0.5219 11.1748 -1.8773 41.4932
BICR 78 GDSC1; GDSC2 0.6359 4.3452 -0.9849 13.61
BHY GDSC1; CTRP2 0.6381 9.29 -0.9761 39.7473
HSC-2 GDSC1; GDSC2; CTRP2 0.7854 10.2721 -1.2212 39.631
SKN-3 GDSC1; GDSC2 1.0379 5.7442 -1.3406 14.5094
NCI-H3118 GDSC1; GDSC2 1.2871 6.0114 -1.2706 13.3804
CAL-33 GDSC1; GDSC2; CTRP2 1.4523 8.4465 0.2202 34.3031
BICR 16 CTRP2 1.4846 13.9943 -2.1633 38.8292
LB771-HNC GDSC1; GDSC2 1.599 8.9485 -2.4868 18.9985
CAL-27 GDSC1; GDSC2; CTRP2 1.6851 7.5311 0.8117 31.8687
UPCI-SCC-090 GDSC1; GDSC2 1.7356 7.6874 -1.7522 14.8823
HSC-4 GDSC2; CTRP2 1.9815 11.8516 -0.6826 34.7309
FaDu GDSC1; GDSC2; CTRP2 2.6196 8.6071 1.392 27.1057
SNU-1041 CTRP2 3.0476 15.117 -1.1801 32.8002
SCC-4 GDSC1; GDSC2; CTRP2 4.4528 16.9942 -0.8075 28.5671
SNU-46 CTRP2 4.5832 15.4784 0.0604 26.0406
BICR 56 CTRP2 6.8857 19.2677 0.1202 21.1361
SNU-1066 CTRP2 7.9061 16.5423 2.2546 12.3209
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BC-3C CTRP2 -4.8264 2.8864 -5.1302 67.1862
UM-UC-1 CTRP2 -2.5934 12.9471 -5.872 53.66
U-BLC1 CTRP2 -2.1985 6.2646 -3.0124 53.6842
SCaBER CTRP2 -1.3916 17.7305 -6.7504 49.813
CAL-29 GDSC1; GDSC2; CTRP2 -1.3911 2.7273 -1.4608 49.553
JMSU-1 CTRP2 -1.3217 10.6994 -3.6138 49.4489
253J CTRP2 -1.233 9.4805 -3.0434 49.0192
SW780 GDSC1; GDSC2 -0.475 3.3937 -1.5727 21.0127
SW1710 GDSC1; GDSC2; CTRP2 -0.2227 5.7627 -0.7202 42.7666
RT-112 GDSC1; GDSC2; CTRP2 0.07 6.0212 -0.4693 41.0571
VM-CUB-1 CTRP2 0.2257 8.3328 -1.0504 41.4257
UM-UC-3 GDSC1; GDSC2; CTRP2 0.5095 9.8776 -1.3482 40.8089
253J-BV CTRP2 0.5988 15.641 -3.8053 43.1903
647V GDSC1; GDSC2; CTRP2 0.776 8.2339 -0.4228 38.196
5637 GDSC1; GDSC2; CTRP2 0.8252 5.5798 0.4684 35.8531
RT-4 GDSC1; GDSC2; CTRP2 0.9398 8.2131 -0.2393 37.2038
TCCSUP GDSC1; GDSC2; CTRP2 1.9506 11.03 -0.3444 34.0719
HT-1197 GDSC1; CTRP2 2.2683 7.1236 1.5854 31.5136
J82 GDSC1; GDSC2; CTRP2 2.5414 14.2151 -1.7638 32.145
KMBC-2 CTRP2 2.8828 10.0417 1.0449 27.473
T24 GDSC1; CTRP2 3.4544 20.1116 -3.2492 35.4005
BFTC-905 GDSC1; GDSC2; CTRP2 4.1641 11.7359 1.5119 22.5178
HT-1376 GDSC1; GDSC2; CTRP2 4.9922 17.462 -0.5633 26.7731
KU-19-19 GDSC1; GDSC2; CTRP2 7.1828 22.8358 -1.4225 24.5762
639V GDSC1; GDSC2; CTRP2 10.4947 21.6957 1.544 11.1156
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ME-180 GDSC1; GDSC2 -1.9729 3.8499 -3.3023 35.4955
HEY GDSC1; GDSC2 -1.9309 2.8221 -2.8309 33.5697
PA-1 GDSC1; GDSC2 -1.12 2.3344 -1.7775 24.8091
CAL-39 GDSC1; GDSC2 -1.0767 1.2432 -1.3372 22.2216
SW962 GDSC1 -0.9945 2.2601 -1.615 28.8936
NEC8 GDSC1; GDSC2 -0.9577 3.6322 -2.1663 26.1263
SKN GDSC1; GDSC2 -0.892 2.2738 -1.5122 22.3773
KGN GDSC1; GDSC2 -0.8795 2.3921 -1.5473 22.5191
NT2-D1 GDSC1; GDSC2 -0.8631 4.1717 -2.3181 26.4766
OMC-1 [Human cervical carcinoma] GDSC1 -0.4483 2.0019 -0.9339 21.4272
TC-YIK GDSC1; GDSC2 -0.3846 3.5361 -1.5491 20.529
OVCA420 GDSC1; GDSC2 -0.2837 3.2967 -1.3379 18.9329
C-33 A GDSC1; GDSC2 -0.2349 3.4828 -1.377 18.9748
NCC-IT GDSC2 -0.1151 8.1581 -3.5461 28.7579
BPH-1 GDSC1; GDSC2 -0.0403 3.4588 -1.1762 17.076
ACC-OV7 GDSC1 0.0878 4.2624 -1.4423 22.2782
OVCA433 GDSC1 0.1118 5.3332 -1.945 25.2028
SKG-IIIa GDSC1; GDSC2 0.1996 4.7189 -1.5624 18.4728
Ca Ski GDSC1; GDSC2 0.3814 5.8745 -1.9702 20.0955
DSH1 GDSC1; GDSC2 0.4411 4.4055 -1.1884 15.4727
SiSo GDSC1; GDSC2 0.4896 4.0074 -0.9476 13.8565
JEG-3 GDSC1 0.4963 4.4735 -1.1726 18.6933
PWR-1E GDSC1; GDSC2 0.5457 4.7932 -1.2873 15.718
LB831-BLC GDSC1; GDSC2 0.692 5.2891 -1.4063 15.9485
SW954 GDSC1 0.8082 3.3974 -0.362 11.4375
HEC-1 GDSC1; GDSC2 0.9631 6.0138 -1.5378 15.8703
C-4-I GDSC1; GDSC2 0.9957 3.9127 -0.4599 9.2486
OV17R GDSC1 0.9975 7.698 -2.3511 23.7655
OVMIU GDSC1; GDSC2 1.0196 4.1082 -0.5378 9.6683
MS751 GDSC1; GDSC2 1.1496 3.81 -0.2823 7.6917
SiHa GDSC1; GDSC2 1.2485 4.9843 -0.7891 10.5834
JAR GDSC1 1.2753 2.7294 0.3527 4.1907
JHOS-3 GDSC1 1.3015 5.6406 -1.074 14.9314
PEO1 GDSC1; GDSC2 1.3307 4.956 -0.7096 9.868
UWB1.289 GDSC1 1.4401 6.0598 -1.1731 15.1395
DoTc2 4510 GDSC1; GDSC2 1.5961 4.0897 -0.0806 5.2902
HT-3 GDSC1; GDSC2 1.7785 6.3229 -1.0438 10.7305
SW756 GDSC1; GDSC2 2.0811 6.0428 -0.6872 7.8792
HeLa GDSC1; GDSC2; CTRP2 5.334 11.3639 2.7716 15.0926
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7714).
2 Clinical pipeline report, company report or official report of AstraZeneca (2009).
3 Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects. Cell Chem Biol. 2019 Mar 21;26(3):366-377.e12. doi: 10.1016/j.chembiol.2018.11.013. Epub 2019 Jan 17.