Details of the Drug

General Information of Drug (ID: DM7VJE1)

Drug Name
IONIS-TMPRSS6-LRx
Indication
Disease Entry ICD 11 Status REF
Beta thalassemia 3A50.2 Phase 2 [1]
Drug Type
Antisense oligonucleotide
Sequence
CUUUATTCCAAAGGGCAGCU
Cross-matching ID
TTD ID
D2MA0E

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TMPRSS6 messenger RNA (TMPRSS6 mRNA) TTNIUKC TMPS6_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04059406) Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS TMPRSS6-LRx. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.