Details of the Drug

General Information of Drug (ID: DM7Y1SO)

Drug Name
UNC0642
Synonyms
1481677-78-4; UNC 0642; UNC-0642; CHEMBL2441082; 2-(4,4-Difluoro-1-piperidinyl)-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine; Barrett; GTPL7017; SCHEMBL17372593; AOB2595; MolPort-035-765-953; EX-A2241; BCP08266; ZINC96285772; BDBM50442103; AKOS024458509; SB19046; CS-5269; NCGC00189140-01; NCGC00189140-02; AS-16721; HY-13980; BC600721; AK547424; UNC0642, > KB-146019; J-008448
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 546.7
Logarithm of the Partition Coefficient (xlogp) 5.7
Rotatable Bond Count (rotbonds) 10
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C29H44F2N6O2
IUPAC Name
2-(4,4-difluoropiperidin-1-yl)-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Canonical SMILES
CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)N5CCC(CC5)(F)F
InChI
InChI=1S/C29H44F2N6O2/c1-21(2)36-14-7-22(8-15-36)32-27-23-19-25(38-3)26(39-18-6-13-35-11-4-5-12-35)20-24(23)33-28(34-27)37-16-9-29(30,31)10-17-37/h19-22H,4-18H2,1-3H3,(H,32,33,34)
InChIKey
RNAMYOYQYRYFQY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
53315878
TTD ID
D0BI4T

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Euchromatic histone-lysine N-methyltransferase 1 (EHMT1) TTOFXD7 EHMT1_HUMAN Inhibitor [1]
Histone-lysine N-methyltransferase EHMT2 (EHMT2) TTS6RZT EHMT2_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 1.5527 3.6701 -1.7015 0.8231
CADO-ES1 GDSC1 0.1878 2.5564 -1.9129 3.8631
ES7 GDSC1 0.3755 3.1647 -2.0783 4.6148
ES1 GDSC1 0.4026 2.8281 -1.9102 3.411
EW-22 GDSC1 0.4478 3.3934 -2.1395 4.8848
EW-11 GDSC1 0.7327 3.8447 -2.1761 4.5481
EW-3 GDSC1 0.7985 5.3797 -2.8444 8.9409
EW-24 GDSC1 0.9365 2.154 -1.3924 0.2071
A-673 GDSC1 1.0116 2.4177 -1.4572 0.3378
EW-18 GDSC1 1.0539 3.8061 -1.9842 2.7715
CHSA8926 GDSC1 1.061 3.009 -1.6569 1.0342
TC-71 GDSC1 1.0849 2.7819 -1.5609 0.6283
EW-13 GDSC1 1.1036 3.0878 -1.6689 1.0485
HOS GDSC1 1.1736 2.8005 -1.5326 0.4787
ES4 GDSC1 1.216 4.2662 -2.0962 3.1909
CAL-78 GDSC1 1.227 3.004 -1.5859 0.6242
SK-ES-1 GDSC1 1.278 2.9743 -1.555 0.4919
CAL-72 GDSC1 1.2875 3.1062 -1.5994 0.6326
H-EMC-SS GDSC1 1.3149 5.0168 -2.3686 4.7054
NOS-1 [Human HNSCC] GDSC1 1.371 3.3429 -1.6534 0.7716
EW-1 GDSC1 1.3941 3.4255 -1.6749 0.8361
SJSA-1 GDSC1 1.4163 3.2228 -1.5913 0.5299
EW-16 GDSC1 1.4478 4.0629 -1.8988 1.7882
U2OS GDSC1 1.4601 3.6294 -1.7244 0.9811
SaOS-2 GDSC1 1.5545 3.4213 -1.6097 0.5127
ES8 GDSC1 1.593 3.2735 -1.5429 0.3168
HuO9 GDSC1 1.6035 4.0451 -1.8224 1.2728
HuO-3N1 GDSC1 1.6366 4.0685 -1.8171 1.2212
SK-PN-DW GDSC1 1.6505 3.4267 -1.5754 0.3737
ES5 GDSC1 1.7013 4.1322 -1.814 1.153
G-292 clone A141B1 GDSC1 1.7192 3.6935 -1.6443 0.5318
CHSA0011 GDSC1 1.7352 4.4285 -1.9138 1.5605
EW-7 GDSC1 1.7403 3.6286 -1.6132 0.434
ES6 GDSC1 1.9172 3.8993 -1.6429 0.4358
MHH-ES-1 GDSC1 1.9335 3.7947 -1.6003 0.3266
CHSA0108 GDSC1 1.9689 5.2484 -2.1333 2.3802
NY GDSC1 2.0865 4.2886 -1.7175 0.5629
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 154 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 1.3486 2.8859 -1.4971 0.2996
WSU-DLCL2 GDSC1 -2.3232 -1.0657 -2.4267 17.2161
JeKo-1 GDSC1 0.1951 4.2223 -2.6948 9.4566
OCI-AML-3 GDSC1 0.2043 2.0399 -1.6725 2.2173
MOLM-13 GDSC1 0.2505 2.5557 -1.8755 3.4754
JVM-3 GDSC1 0.2565 4.3613 -2.7195 9.4655
RL GDSC1 0.327 7.7251 -4.3121 19.1337
OCI-M1 GDSC1 0.3356 1.8129 -1.5106 1.0801
697 GDSC1 0.3577 4.0997 -2.5265 7.8313
Karpas-299 GDSC1 0.3796 5.197 -3.0377 11.3308
EoL-1 GDSC1 0.3895 2.5092 -1.7766 2.5625
WIL2 NS GDSC1 0.3985 2.3372 -1.6977 2.0562
IM-9 GDSC1 0.3995 2.1575 -1.6213 1.6038
DEL GDSC1 0.403 2.7184 -1.8612 3.0857
BV-173 GDSC1 0.41 7.1686 -3.9772 17.0772
Farage GDSC1 0.4368 2.9851 -1.9608 3.6841
HH [Human lymphoma] GDSC1 0.4788 5.8242 -3.2721 12.6081
L-428 GDSC1 0.4982 2.7782 -1.835 2.7473
CML-T1 GDSC1 0.5252 3.2096 -2.0106 3.8464
MOLT-13 GDSC1 0.5391 2.679 -1.7705 2.2785
TK [Human B-cell lymphoma] GDSC1 0.5689 2.8586 -1.832 2.6091
SU-DHL-10 GDSC1 0.5689 1.5286 -1.3087 0.1484
GA-10 GDSC1 0.592 2.9715 -1.8685 2.7998
Karpas-422 GDSC1 0.5932 3.8414 -2.257 5.3855
P30/OHK GDSC1 0.5936 3.717 -2.1999 4.9922
NB4 GDSC1 0.5983 1.811 -1.3976 0.371
A3/Kawakami GDSC1 0.6081 1.8563 -1.4103 0.4069
Jiyoye GDSC1 0.6085 3.4982 -2.0921 4.23
AMO1 GDSC1 0.6189 3.4366 -2.0586 3.9854
MOLP-8 GDSC1 0.6384 2.8337 -1.785 2.2138
SK-MM-2 GDSC1 0.6492 2.7718 -1.7535 2.0122
L-363 GDSC1 0.7132 2.7234 -1.7019 1.635
MOLM-16 GDSC1 0.7186 2.6606 -1.6737 1.4772
NCI-H929 GDSC1 0.7325 2.8638 -1.7504 1.8782
SU-DHL-16 GDSC1 0.74 2.3445 -1.5391 0.8058
BL-41 GDSC1 0.7511 4.636 -2.5268 6.8923
OCI-AML-2 GDSC1 0.7665 2.2255 -1.4831 0.561
SU-DHL-8 GDSC1 0.7699 2.4576 -1.5698 0.9136
Karpas-620 GDSC1 0.7725 2.1008 -1.4349 0.3924
NKM-1 GDSC1 0.7896 5.1995 -2.7654 8.4288
HAL-01 GDSC1 0.7927 3.9446 -2.1864 4.4993
P32/ISH GDSC1 0.7977 2.2628 -1.4843 0.5441
Hs 445 GDSC1 0.798 3.0573 -1.7985 2.0613
SU-DHL-5 GDSC1 0.8071 2.1584 -1.4424 0.3967
JVM-2 GDSC1 0.8139 4.0904 -2.2396 4.8112
JJN-3 GDSC1 0.8182 2.4086 -1.5305 0.7056
RPMI-8226 GDSC1 0.8274 3.9055 -2.1493 4.1883
RPMI-8402 GDSC1 0.8307 2.7714 -1.6661 1.3087
MOLT-4 GDSC1 0.8572 4.0145 -2.1809 4.3392
JURL-MK1 GDSC1 0.862 2.7629 -1.6485 1.1888
HEL GDSC1 0.8655 2.3441 -1.4871 0.51
THP-1 GDSC1 0.8667 2.5549 -1.5657 0.8107
Sc-1 GDSC1 0.8672 3.0079 -1.7445 1.6711
NOMO-1 GDSC1 0.8723 2.3888 -1.5009 0.5542
TUR GDSC1 0.8736 2.5815 -1.5729 0.8352
Jurkat GDSC1 0.8747 2.9006 -1.6976 1.4177
KOPN-8 GDSC1 0.8752 2.9022 -1.6979 1.419
Ramos.2G6.4C10 GDSC1 0.8757 4.6422 -2.4535 6.1206
A4/Fukuda GDSC1 0.8782 2.5948 -1.576 0.8447
DG-75 GDSC1 0.8872 4.1871 -2.2408 4.676
CCRF-CEM GDSC1 0.8907 3.3815 -1.8879 2.4463
Daudi GDSC1 0.9021 2.6778 -1.5977 0.917
HC-1 GDSC1 0.9022 3.7459 -2.0379 3.3409
ALL-SIL GDSC1 0.9263 2.9267 -1.6843 1.2949
NU-DUL-1 GDSC1 0.9265 2.55 -1.5389 0.6571
RPMI-6666 GDSC1 0.929 3.0682 -1.7397 1.5715
KCL-22 GDSC1 0.9306 3.3241 -1.8439 2.1356
MOLT-16 GDSC1 0.9614 2.2725 -1.4246 0.2736
HT GDSC1 0.9709 7.3602 -3.6735 13.7655
CMK GDSC1 0.9782 2.4881 -1.4954 0.4698
KE-37 GDSC1 0.9898 2.6332 -1.5442 0.632
ME1 GDSC1 0.9903 2.1009 -1.3552 0.122
L-540 GDSC1 0.9937 2.9437 -1.6609 1.1152
SUP-T1 GDSC1 1.0251 2.867 -1.6177 0.8963
HL-60 GDSC1 1.0294 2.4945 -1.4779 0.388
RC-K8 GDSC1 1.0306 2.322 -1.4166 0.2286
K-562 GDSC1 1.0336 3.1113 -1.709 1.3015
OPM-2 GDSC1 1.0361 2.7757 -1.5785 0.7287
Karpas-1106P GDSC1 1.0422 3.5617 -1.8875 2.2294
LAMA-84 GDSC1 1.0548 3.5079 -1.8591 2.0544
CRO-AP2 GDSC1 1.0649 3.5289 -1.8629 2.0621
P31/FUJ GDSC1 1.0685 2.4035 -1.4312 0.2482
EHEB GDSC1 1.0716 3.178 -1.7182 1.3063
BALL-1 GDSC1 1.0736 2.8209 -1.58 0.7068
SUP-B8 GDSC1 1.0824 2.8188 -1.5756 0.6841
SUP-M2 GDSC1 1.0853 2.28 -1.3827 0.1453
CTB-1 GDSC1 1.0886 3.9559 -2.03 2.9915
MV4-11 GDSC1 1.0913 3.2922 -1.7546 1.4627
BE-13 GDSC1 1.0925 2.749 -1.5457 0.5697
MHH-CALL-2 GDSC1 1.0996 2.5147 -1.4587 0.3033
BC-1 GDSC1 1.1009 8.6991 -4.2299 16.5271
KG-1 GDSC1 1.1028 3.437 -1.8073 1.7176
MN-60 GDSC1 1.1224 2.9611 -1.6125 0.7969
SKM-1 GDSC1 1.1323 2.5859 -1.4716 0.323
Reh GDSC1 1.1466 2.7271 -1.5166 0.4437
SU-DHL-4 GDSC1 1.1598 2.6958 -1.5003 0.3891
EB2 GDSC1 1.16 2.8236 -1.5463 0.5306
EM-2 GDSC1 1.1608 2.8606 -1.5595 0.5746
Kasumi-1 GDSC1 1.1665 11.4664 -5.5328 22.2832
MC116 GDSC1 1.1722 2.2288 -1.3359 0.0653
RCH-ACV GDSC1 1.1753 3.4108 -1.7635 1.4166
EJM GDSC1 1.1801 3.4004 -1.7572 1.3814
P12-Ichikawa GDSC1 1.1811 2.4375 -1.4026 0.1559
KMS-11 GDSC1 1.2114 5.3177 -2.5617 6.1427
Namalwa GDSC1 1.2149 2.6991 -1.4808 0.3122
YT GDSC1 1.2155 2.4498 -1.3948 0.1347
Karpas-231 GDSC1 1.2233 2.4952 -1.4074 0.1537
QIMR-WIL GDSC1 1.224 3.471 -1.7654 1.3752
Raji GDSC1 1.2265 2.7553 -1.4963 0.3475
Ku812 GDSC1 1.2504 3.2803 -1.6799 0.9687
CTV-1 GDSC1 1.2602 3.1751 -1.6361 0.7855
MEG-01 GDSC1 1.2622 4.0775 -1.9933 2.5243
JSC-1 GDSC1 1.266 3.4898 -1.7541 1.2806
SR GDSC1 1.2663 2.7889 -1.4934 0.3229
ATN-1 GDSC1 1.2776 2.8699 -1.5178 0.3826
OCI-AML-5 GDSC1 1.294 2.7981 -1.4864 0.2948
NALM-6 GDSC1 1.2947 2.9345 -1.5343 0.4213
Granta-519 GDSC1 1.3256 3.0907 -1.5787 0.5404
MHH-PREB-1 GDSC1 1.3282 2.8049 -1.4763 0.259
CA46 GDSC1 1.3333 8.1609 -3.8122 13.6435
SU-DHL-6 GDSC1 1.337 3.0023 -1.5425 0.4242
PF-382 GDSC1 1.365 3.3878 -1.6727 0.8494
L-1236 GDSC1 1.382 3.5979 -1.7455 1.1351
PL-21 GDSC1 1.3916 3.5133 -1.7091 0.9736
ROS-50 GDSC1 1.4019 4.0678 -1.922 1.9593
ARH-77 GDSC1 1.4157 8.9282 -4.1238 15.1547
OCI-Ly19 GDSC1 1.4314 3.1464 -1.5581 0.4236
GR-ST GDSC1 1.4478 4.3585 -2.0187 2.417
DND-41 GDSC1 1.4526 3.8276 -1.8037 1.3288
WSU-NHL GDSC1 1.4581 2.8982 -1.462 0.1904
RPMI-8866 GDSC1 1.4588 3.2008 -1.5672 0.436
LC4-1 GDSC1 1.4839 3.5587 -1.6879 0.8209
KM-H2 GDSC1 1.489 3.2997 -1.5911 0.4907
DB GDSC1 1.5046 3.158 -1.535 0.3313
KMOE-2 GDSC1 1.5149 3.4165 -1.6232 0.5761
U-698-M GDSC1 1.5161 3.7012 -1.7282 0.9524
ML-2 GDSC1 1.522 3.2027 -1.5442 0.3473
CESS GDSC1 1.5225 3.5633 -1.674 0.7434
U266B1 GDSC1 1.5265 3.2277 -1.5513 0.3634
VL51 GDSC1 1.5391 3.6768 -1.7095 0.8629
Loucy GDSC1 1.5515 3.0484 -1.4802 0.1988
VAL GDSC1 1.5636 3.3867 -1.5938 0.4616
LP-1 GDSC1 1.5769 3.1562 -1.5081 0.2458
HDLM-2 GDSC1 1.5783 3.9712 -1.8048 1.2187
Karpas-45 GDSC1 1.5947 3.2982 -1.5509 0.3352
RS4;11 GDSC1 1.6176 3.3999 -1.5782 0.3945
H9 GDSC1 1.6732 3.2186 -1.4953 0.1944
GDM-1 GDSC1 1.6874 4.1413 -1.8234 1.2041
SUP-HD1 GDSC1 1.7649 4.0385 -1.7524 0.8641
ST486 GDSC1 1.778 3.598 -1.5885 0.3557
KY821 GDSC1 1.808 3.5303 -1.5541 0.2687
ALL-PO GDSC1 1.858 4.1882 -1.7703 0.8659
Mono-Mac-6 GDSC1 1.9675 5.0346 -2.0485 1.9602
MLMA GDSC1 1.9758 3.7959 -1.5855 0.2812
⏷ Show the Full List of 154 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-51 GDSC1 1.1763 3.4054 -1.7609 1.4029
KYAE-1 GDSC1 1.3046 3.6063 -1.7826 1.3754
SK-GT-4 GDSC1 1.4922 4.4475 -2.0338 2.4419
ESO-26 GDSC1 1.5314 3.3958 -1.6094 0.5239
OACM5.1 C GDSC1 1.703 4.0809 -1.7937 1.0688
KYSE-220 GDSC1 1.7432 3.7031 -1.6386 0.5031
KYSE-50 GDSC1 1.785 3.6127 -1.5911 0.3592
FLO-1 GDSC1 1.7958 4.665 -1.9797 1.8097
HCE-4 GDSC1 1.8861 3.5204 -1.5232 0.19
TE-12 GDSC1 1.893 4.2671 -1.7855 0.8973
OACP4 C GDSC1 2.1541 4.1146 -1.6314 0.3205
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 1.6914 3.964 -1.7546 0.9241
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGW GDSC1 0.3746 9.5567 -5.1811 23.0516
SK-N-DZ GDSC1 0.409 2.9347 -1.9542 3.6944
LA-N-6 GDSC1 0.4147 2.3834 -1.709 2.0993
NB1 GDSC1 0.4676 2.8792 -1.8962 3.1967
SJNB-14 GDSC1 0.5923 2.2862 -1.5817 1.15
SK-N-BE(2)-M17 GDSC1 0.6486 2.6448 -1.7009 1.7135
SK-N-FI GDSC1 0.6732 2.4004 -1.5903 1.105
SJNB-7 GDSC1 0.7099 17.9173 -9.0742 32.8656
GOTO GDSC1 0.7103 2.9735 -1.8075 2.2395
SJNB-13 GDSC1 0.7108 2.5357 -1.627 1.2456
SK-N-MC-IXC GDSC1 0.7272 2.0115 -1.4201 0.3708
CHP-126 GDSC1 0.8157 2.7026 -1.6456 1.2234
Kelly GDSC1 0.8732 2.5742 -1.5703 0.8245
SJNB-17 GDSC1 0.8776 3.1523 -1.7987 1.9538
SK-N-AS GDSC1 1.066 2.6966 -1.537 0.5563
KP-N-YN GDSC1 1.2255 3.0143 -1.5903 0.6407
IMR-5 GDSC1 1.2972 3.4165 -1.7121 1.0652
CHP-212 GDSC1 1.3685 3.2584 -1.6232 0.6638
SK-N-SH GDSC1 1.3954 3.3194 -1.6349 0.6879
SiMa GDSC1 1.4052 3.9515 -1.8738 1.7109
SJNB-10 GDSC1 1.4439 3.0998 -1.537 0.3609
SJNB-5 GDSC1 1.4509 3.3216 -1.6137 0.5819
NB(TU)1 GDSC1 1.7005 3.3954 -1.5462 0.2866
GI-ME-N GDSC1 1.8392 4.7591 -1.9973 1.849
SJNB-12 GDSC1 2.078 4.081 -1.6473 0.3829
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 1.1625 2.8215 -1.5446 0.5235
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1419 GDSC1 -0.2454 2.7475 -2.2882 7.7033
HCC202 GDSC1 0.3838 3.9616 -2.4441 7.1808
HCC2218 GDSC1 0.3924 5.1306 -2.9968 11.0191
MDA-MB-231 GDSC1 0.6385 2.7633 -1.7553 2.0384
HCC1500 GDSC1 0.7363 3.0406 -1.8226 2.2901
BT-20 GDSC1 0.7404 2.5644 -1.6249 1.2027
MCF-7 GDSC1 0.966 3.5079 -1.903 2.4248
CAMA-1 GDSC1 0.9769 2.6417 -1.5526 0.6726
JIMT-1 GDSC1 0.9837 2.4401 -1.4759 0.4055
HCC2157 GDSC1 0.9865 3.269 -1.7941 1.7884
HCC38 GDSC1 0.9895 4.5037 -2.3239 5.025
COLO 824 GDSC1 1.0313 3.3173 -1.7925 1.7253
Hs 578T GDSC1 1.0314 3.9479 -2.0565 3.2425
DU4475 GDSC1 1.0672 2.4596 -1.4513 0.2978
MDA-MB-468 GDSC1 1.0853 2.8764 -1.596 0.7601
MRK-nu-1 GDSC1 1.1135 2.8129 -1.5609 0.6093
HCC1143 GDSC1 1.1283 3.7797 -1.9357 2.383
OCUB-M GDSC1 1.1335 3.0454 -1.6398 0.8986
Evsa-T GDSC1 1.1556 2.6161 -1.4736 0.3183
MFM-223 GDSC1 1.1637 2.9539 -1.5929 0.6914
HDQ-P1 GDSC1 1.1643 3.1513 -1.6672 0.9877
BT-474 GDSC1 1.1782 2.783 -1.5245 0.4513
MDA-MB-175-VII GDSC1 1.1804 2.7945 -1.5279 0.4603
MDA-MB-361 GDSC1 1.2058 3.1955 -1.6665 0.9496
EFM-19 GDSC1 1.235 3.531 -1.7841 1.4538
HCC1806 GDSC1 1.2477 2.7862 -1.4993 0.3462
EFM-192A GDSC1 1.2617 2.7835 -1.4932 0.3244
CAL-85-1 GDSC1 1.2703 3.3716 -1.7064 1.0639
BT-549 GDSC1 1.2755 3.1789 -1.6312 0.756
HCC70 GDSC1 1.3247 3.022 -1.5543 0.4649
CAL-51 GDSC1 1.379 3.1334 -1.5735 0.4947
CAL-120 GDSC1 1.3791 3.172 -1.5874 0.5381
BT-483 GDSC1 1.3886 9.7602 -4.543 17.3664
HCC1954 GDSC1 1.4385 3.2278 -1.5846 0.4973
HCC1569 GDSC1 1.4577 4.7356 -2.1712 3.2666
HCC1937 GDSC1 1.5075 3.5283 -1.6671 0.7287
MDA-MB-436 GDSC1 1.5424 3.1673 -1.5244 0.2923
HCC1187 GDSC1 1.5596 3.335 -1.5769 0.4165
MDA-MB-157 GDSC1 1.5788 4.0635 -1.8402 1.3748
T-47D GDSC1 1.5791 3.5103 -1.6323 0.569
HCC1428 GDSC1 1.5942 2.9736 -1.4402 0.1249
UACC-893 GDSC1 1.7556 3.814 -1.6738 0.6023
MDA-MB-415 GDSC1 1.8082 4.067 -1.7455 0.8102
MDA-MB-453 GDSC1 1.8357 3.7536 -1.6218 0.4155
ZR-75-30 GDSC1 1.8375 3.6346 -1.5796 0.3135
MDA-MB-330 GDSC1 1.968 4.0588 -1.6804 0.5143
HCC1395 GDSC1 2.0234 3.5443 -1.4842 0.109
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MOG-G-UVW GDSC1 0.256 4.6279 -2.8484 10.3722
D-336MG GDSC1 0.3369 16.4012 -8.6131 32.8939
LN-18 GDSC1 0.567 1.8927 -1.4403 0.5418
D-263MG GDSC1 0.587 2.8933 -1.8373 2.6128
SF268 GDSC1 0.6014 3.1041 -1.9212 3.1187
YKG-1 GDSC1 0.6631 2.3145 -1.561 0.9753
Becker GDSC1 0.7437 3.7919 -2.1461 4.3268
SF295 GDSC1 0.8047 3.1361 -1.8281 2.2223
Hs 683 GDSC1 0.8352 2.2081 -1.4495 0.4036
D-542MG GDSC1 0.8441 2.9763 -1.7426 1.6898
KNS-42 GDSC1 0.8798 2.4503 -1.5208 0.6219
GaMG GDSC1 0.9243 2.4841 -1.5153 0.5712
CAS-1 GDSC1 0.9736 2.4443 -1.4813 0.4274
AM-38 GDSC1 0.9772 3.2828 -1.8041 1.8541
A-172 GDSC1 1.0281 2.9919 -1.6646 1.0991
DK-MG GDSC1 1.0591 2.6127 -1.5091 0.4678
NMC-G1 GDSC1 1.076 2.6165 -1.5039 0.4423
U-251MG GDSC1 1.0775 2.4737 -1.4524 0.2965
D283 Med GDSC1 1.0899 2.6832 -1.5227 0.4941
LN-229 GDSC1 1.1368 2.6679 -1.499 0.3966
Onda 10 GDSC1 1.1708 3.2673 -1.7092 1.1666
KS-1 [Human Krukenberg tumour] GDSC1 1.1759 3.5332 -1.812 1.6567
T98G GDSC1 1.2148 3.4986 -1.7804 1.4571
LNZTA3WT4 GDSC1 1.23 2.9879 -1.5788 0.5978
SW1783 GDSC1 1.2378 3.3957 -1.7298 1.1967
SW1088 GDSC1 1.2402 3.4311 -1.7425 1.2525
LN-405 GDSC1 1.2466 2.7066 -1.4718 0.2778
U-118MG GDSC1 1.2542 3.1347 -1.6234 0.7418
U-87MG ATCC GDSC1 1.2648 2.6727 -1.4534 0.2303
MOG-G-CCM GDSC1 1.3031 3.5633 -1.7664 1.3016
D-566MG GDSC1 1.3672 3.1764 -1.5936 0.5648
KNS-81-FD GDSC1 1.3735 3.2014 -1.6003 0.583
YH-13 GDSC1 1.3857 2.8453 -1.4696 0.2258
Daoy GDSC1 1.3987 3.2035 -1.5912 0.5392
D-423MG GDSC1 1.4084 3.6509 -1.7545 1.1508
SK-MG-1 GDSC1 1.4146 3.1304 -1.5588 0.4335
Onda 11 GDSC1 1.4312 3.6825 -1.7569 1.1412
42-MG-BA GDSC1 1.4372 3.2489 -1.5927 0.5228
GB-1 GDSC1 1.4453 2.9016 -1.4676 0.2044
DBTRG-05MG GDSC1 1.4465 3.0331 -1.5126 0.2998
SF126 GDSC1 1.4821 2.8355 -1.4324 0.1357
M059J GDSC1 1.4979 3.2659 -1.5756 0.4412
8-MG-BA GDSC1 1.5235 3.0624 -1.495 0.2354
ONS-76 GDSC1 1.5581 3.3857 -1.5955 0.4693
SF539 GDSC1 1.6791 3.2485 -1.5034 0.2073
KALS-1 GDSC1 1.7022 3.9135 -1.7314 0.83
D-247MG GDSC1 1.7479 3.9821 -1.7383 0.8245
SNB-75 GDSC1 1.7847 3.6561 -1.6064 0.3973
D-502MG GDSC1 1.8266 3.8964 -1.6761 0.5716
GI-1 GDSC1 1.9352 3.8034 -1.6027 0.3314
H4 GDSC1 2.0307 3.74 -1.5471 0.1956
D-392MG GDSC1 2.0548 4.7826 -1.9124 1.2694
KINGS-1 GDSC1 2.1674 4.4287 -1.7368 0.5791
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 1.1115 2.9061 -1.5963 0.7418
ETK-1 GDSC1 1.2658 3.3548 -1.7019 1.0485
TGBC24TKB GDSC1 1.4559 3.3733 -1.6306 0.6349
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1 1.1698 2.6301 -1.4732 0.3114
MFE-319 GDSC1 1.2358 2.7021 -1.4742 0.2876
EN GDSC1 1.3819 2.8778 -1.4821 0.2535
MFE-296 GDSC1 1.5199 3.2082 -1.5469 0.3549
AN3-CA GDSC1 1.5214 3.2428 -1.5586 0.3843
KLE GDSC1 1.531 3.3978 -1.6102 0.5266
RL95-2 GDSC1 1.5416 3.125 -1.51 0.261
MFE-280 GDSC1 1.7899 4.308 -1.8435 1.2026
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 GDSC1 -0.9936 5.4499 -4.2196 23.0527
NCC021 GDSC1 0.3293 3.127 -2.089 4.7903
BFTC-909 GDSC1 0.7828 2.5856 -1.6142 1.106
A-704 GDSC1 0.8171 3.2242 -1.859 2.385
RCC10RGB GDSC1 0.8222 2.7271 -1.6524 1.2498
SN12C GDSC1 0.8664 3.035 -1.7559 1.7335
NCC010 GDSC1 0.9281 8.352 -4.1829 16.7414
SW13 GDSC1 0.9404 2.8088 -1.6318 1.0332
LB2241-RCC GDSC1 0.988 3.6573 -1.9549 2.6968
KTCTL-13 GDSC1 1.0112 3.3385 -1.8107 1.8467
Caki-1 GDSC1 1.0762 4.0653 -2.0833 3.3343
OS-RC-2 GDSC1 1.1192 2.9362 -1.6044 0.7675
A-498 GDSC1 1.1352 2.8814 -1.5775 0.6545
HA7-RCC GDSC1 1.1558 3.5587 -1.8316 1.7811
KMRC-20 GDSC1 1.27 3.07 -1.5931 0.6216
RXF 393L GDSC1 1.285 10.2466 -4.8515 19.0927
KTCTL-26A GDSC1 1.3146 3.8056 -1.8571 1.728
VMRC-RCZ GDSC1 1.3514 2.8643 -1.4885 0.2784
ACHN GDSC1 1.3641 3.3476 -1.658 0.7938
KTCTL-195 GDSC1 1.4771 3.616 -1.7122 0.9192
786-O GDSC1 1.6224 3.4491 -1.5938 0.4342
769-P GDSC1 1.6295 3.2086 -1.5073 0.2285
CAL-54 GDSC1 1.6664 3.727 -1.677 0.6635
LB1047-RCC GDSC1 1.6792 4.2333 -1.8623 1.3804
LB996-RCC GDSC1 1.705 3.838 -1.7024 0.7258
BB65-RCC GDSC1 1.7825 3.9305 -1.7056 0.6894
KTCTL-1M GDSC1 1.7886 4.0351 -1.7416 0.8092
KTCTL-140 GDSC1 1.8668 3.9485 -1.6794 0.5609
KTCTL-21 GDSC1 2.0422 4.4438 -1.7909 0.8191
TK-10 GDSC1 2.1248 4.4351 -1.7554 0.656
SW156 GDSC1 2.1878 4.1251 -1.6229 0.2925
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2998 GDSC1 -0.0553 2.8192 -2.1913 6.4568
MDST8 GDSC1 0.3994 6.5471 -3.6804 15.3834
SW1116 GDSC1 0.5227 2.373 -1.65 1.5978
SW48 GDSC1 0.5418 3.6638 -2.2067 5.1486
COLO205 GDSC1 0.5534 2.0659 -1.5123 0.8569
SNU-1040 GDSC1 0.56 3.8696 -2.2901 5.6867
NCI-H716 GDSC1 0.6195 3.8965 -2.2664 5.3933
NCI-H508 GDSC1 0.6513 10.6147 -5.4952 23.5284
LS180 GDSC1 0.6762 2.358 -1.5722 1.0149
HCT 15 GDSC1 0.7285 3.5339 -2.0401 3.6585
HCT 116 GDSC1 0.7622 2.381 -1.5436 0.8061
LS411N GDSC1 0.8271 2.3615 -1.5091 0.6155
LS1034 GDSC1 0.8418 2.5549 -1.5763 0.8772
C2BBe1 GDSC1 0.8701 3.8855 -2.1166 3.8971
SW948 GDSC1 0.9248 2.2612 -1.4343 0.3145
HT-29 GDSC1 0.9642 2.5148 -1.5107 0.5293
RKO GDSC1 1.0059 2.804 -1.6018 0.8456
DiFi GDSC1 1.0224 3.4417 -1.8476 2.0332
NCI-H747 GDSC1 1.0258 5.9175 -2.9514 9.1077
HT115 GDSC1 1.0295 2.3672 -1.4328 0.2667
RCM-1 [Human ESC] GDSC1 1.0571 2.5185 -1.476 0.369
LS513 GDSC1 1.094 2.6513 -1.5095 0.4499
SNU-C1 GDSC1 1.1114 7.854 -3.815 14.2223
SNU-81 GDSC1 1.1309 2.9422 -1.6019 0.7489
SK-CO-1 GDSC1 1.1689 3.0668 -1.6331 0.8427
SNU-61 GDSC1 1.171 3.5952 -1.8393 1.8029
SW1417 GDSC1 1.1896 3.0152 -1.6052 0.7192
GP5d GDSC1 1.1979 2.891 -1.556 0.5404
SNU-C2B GDSC1 1.2314 4.3043 -2.1045 3.2164
CW-2 GDSC1 1.2712 3.4034 -1.7183 1.1147
LS123 GDSC1 1.2837 3.3481 -1.6917 0.9902
SW1463 GDSC1 1.3539 2.8528 -1.4836 0.2664
SW837 GDSC1 1.4241 3.2259 -1.5895 0.5199
KM12 GDSC1 1.4464 3.315 -1.6131 0.5824
SNU-407 GDSC1 1.4953 3.5302 -1.6727 0.757
T84 GDSC1 1.5421 3.6282 -1.6902 0.7887
COLO 320HSR GDSC1 1.5484 3.5749 -1.668 0.7054
CL-11 GDSC1 1.598 3.328 -1.5601 0.3565
SNU-C5 GDSC1 1.6127 3.8229 -1.734 0.9029
SW620 GDSC1 1.6275 3.2373 -1.5179 0.2502
SW626 GDSC1 1.6311 4.2615 -1.8945 1.5737
LoVo GDSC1 1.7133 4.5245 -1.9614 1.8081
CaR-1 GDSC1 1.8104 3.3369 -1.4876 0.1507
COLO 678 GDSC1 1.8918 3.5994 -1.548 0.2324
CCK-81 GDSC1 1.9659 4.1372 -1.7093 0.5993
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 1.0129 2.8032 -1.5985 0.8266
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-6 GDSC1 0.5518 1.561 -1.3261 0.1925
SNU-398 GDSC1 0.5957 3.1876 -1.9611 3.3864
JHH-2 GDSC1 0.6395 2.4686 -1.6332 1.3591
JHH-4 GDSC1 0.7375 2.7839 -1.715 1.6752
HuH-1 GDSC1 0.8637 2.3684 -1.4968 0.5453
SK-HEP-1 GDSC1 0.8938 2.4689 -1.522 0.6165
Hep-G2/C3A GDSC1 0.9347 2.5175 -1.5235 0.5938
SNU-387 GDSC1 1.1205 4.1422 -2.093 3.3219
JHH-1 GDSC1 1.1544 2.8579 -1.5611 0.584
Huh-7 GDSC1 1.1973 3.0391 -1.611 0.7354
Hep 3B2.1-7 GDSC1 1.205 3.079 -1.6227 0.7746
HLE GDSC1 1.2167 3.3317 -1.7142 1.1462
SNU-423 GDSC1 1.4766 3.2754 -1.5871 0.4851
SNU-449 GDSC1 1.5771 3.6666 -1.6903 0.7657
JHH-7 GDSC1 1.6738 3.2893 -1.5193 0.239
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 172 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H647 GDSC1 -0.921 4.4982 -3.6836 19.7365
NCI-H1792 GDSC1 -0.9119 0.9199 -1.8876 6.6868
NCI-H1781 GDSC1 -0.5304 1.805 -2.033 6.591
NCI-H1651 GDSC1 -0.2917 2.2673 -2.0876 6.3188
NCI-H1694 GDSC1 0.026 2.4615 -1.9687 4.6209
HCC78 GDSC1 0.1206 4.1235 -2.6986 9.6896
EMC-BAC-2 GDSC1 0.266 4.7805 -2.9152 10.8082
SHP-77 GDSC1 0.2971 2.1371 -1.665 2.0165
NCI-H1688 GDSC1 0.3243 5.3276 -3.1396 12.1691
NCI-H835 GDSC1 0.3529 3.663 -2.3235 6.3971
NCI-H1876 GDSC1 0.3684 2.4764 -1.7738 2.581
CPC-N GDSC1 0.4386 2.7899 -1.8728 3.0968
DMS 114 GDSC1 0.5139 2.4468 -1.6851 1.8093
NCI-H2595 GDSC1 0.5435 12.1549 -6.3395 26.7924
LCLC-97TM1 GDSC1 0.5488 4.2237 -2.4615 6.9072
SBC-5 GDSC1 0.5571 1.7147 -1.3787 0.3342
NCI-H69 GDSC1 0.5988 3.358 -2.0349 3.8667
NCI-H292 GDSC1 0.6475 5.3471 -2.9278 9.8784
Lu-139 GDSC1 0.6527 3.3374 -1.9955 3.507
NCI-H1304 GDSC1 0.6653 12.1648 -6.2513 26.1799
NCI-H841 GDSC1 0.6738 3.525 -2.0668 3.9352
NCI-H810 GDSC1 0.6749 2.2607 -1.5349 0.8452
BEN GDSC1 0.6897 1.7598 -1.3451 0.1867
NCI-H2291 GDSC1 0.7397 30.6426 -15.3959 39.6809
NCI-H345 GDSC1 0.7655 2.0447 -1.4174 0.3426
LCLC-103H GDSC1 0.7725 2.3341 -1.5214 0.7051
NCI-H847 GDSC1 0.7728 3.3355 -1.9295 2.8802
EBC-1 GDSC1 0.8074 2.7268 -1.659 1.2988
NCI-H1092 GDSC1 0.8092 3.299 -1.8948 2.6104
NCI-H526 GDSC1 0.8345 2.2805 -1.4761 0.4914
NCI-H1105 GDSC1 0.8743 3.1564 -1.802 1.9767
HOP-92 GDSC1 0.8794 4.344 -2.3158 5.1886
NCI-H1573 GDSC1 0.8854 3.1028 -1.7746 1.8105
LB647-SCLC GDSC1 0.9077 2.7486 -1.6226 1.0226
DMS 79 GDSC1 0.92 4.2034 -2.2294 4.5385
NCI-H2444 GDSC1 0.9311 2.3069 -1.4482 0.3502
NCI-H2803 GDSC1 0.9387 2.798 -1.6283 1.0192
NCI-H226 GDSC1 0.9485 2.5534 -1.5312 0.6127
IST-SL1 GDSC1 0.955 3.0266 -1.711 1.3955
NCI-H838 GDSC1 0.9632 2.5088 -1.5088 0.5237
NCI-H209 GDSC1 0.9649 6.1974 -3.1224 10.3671
NCI-H2405 GDSC1 0.9776 10.5155 -5.2043 21.4547
NCI-H1568 GDSC1 0.9859 3.3327 -1.8204 1.9316
NCI-H460 GDSC1 1.006 2.3156 -1.4233 0.253
IA-LM GDSC1 1.0256 2.4545 -1.465 0.3531
COR-L23 GDSC1 1.0304 2.678 -1.5443 0.6051
COR-L279 GDSC1 1.0365 3.3651 -1.8095 1.8088
A-427 GDSC1 1.0427 4.3551 -2.2279 4.3005
NCI-H2122 GDSC1 1.0476 2.8132 -1.5878 0.7566
NCI-H290 GDSC1 1.0544 2.8076 -1.5829 0.7322
NCI-H1436 GDSC1 1.0583 3.1387 -1.7087 1.2747
LOU-NH91 GDSC1 1.0586 2.8716 -1.6053 0.8175
NCI-H1770 GDSC1 1.0636 2.7798 -1.5687 0.6716
HARA [Human squamous cell lung carcinoma] GDSC1 1.0636 3.4868 -1.8462 1.9723
NCI-H1155 GDSC1 1.0666 2.8136 -1.5802 0.7127
NCI-H1435 GDSC1 1.0699 3.0213 -1.6577 1.0299
NCI-H196 GDSC1 1.0717 2.4754 -1.4552 0.306
NCI-H513 GDSC1 1.082 3.382 -1.7948 1.6771
NCI-H2591 GDSC1 1.0831 3.6824 -1.9175 2.3426
NCI-H2141 GDSC1 1.099 2.5309 -1.4646 0.3188
NCI-H446 GDSC1 1.1018 4.6415 -2.3215 4.7949
NCI-H1975 GDSC1 1.104 3.1103 -1.6774 1.0859
NCI-H2227 GDSC1 1.1047 3.2122 -1.7168 1.2664
HCC44 GDSC1 1.1099 3.0314 -1.6445 0.9377
NCI-H2795 GDSC1 1.128 3.2352 -1.7155 1.2371
NCI-H2087 GDSC1 1.1289 3.5977 -1.8603 1.9658
NCI-H650 GDSC1 1.1372 2.8586 -1.5682 0.6199
NCI-H2373 GDSC1 1.1378 2.9789 -1.6129 0.7865
LXF 289 GDSC1 1.1468 3.5939 -1.8502 1.8895
NCI-H2722 GDSC1 1.1514 2.681 -1.4982 0.3871
COR-L95 GDSC1 1.1591 2.9073 -1.5774 0.6384
NCI-H1793 GDSC1 1.1606 3.418 -1.773 1.4786
KNS-62 GDSC1 1.1638 2.8361 -1.5494 0.5387
NCI-H2030 GDSC1 1.1675 2.7424 -1.5141 0.4254
NCI-H211 GDSC1 1.1686 5.2998 -2.5787 6.3408
NCI-H720 GDSC1 1.1831 2.5057 -1.4252 0.1976
RERF-LC-MS GDSC1 1.1912 2.6695 -1.4792 0.3178
Lu-134-A GDSC1 1.2197 3.6508 -1.8389 1.7438
LK-2 GDSC1 1.2234 3.8483 -1.9175 2.1552
NCI-H2170 GDSC1 1.2241 2.8733 -1.5394 0.4726
NCI-H2081 GDSC1 1.2302 3.4132 -1.74 1.2504
COLO 668 GDSC1 1.2345 2.9302 -1.556 0.519
UMC-11 GDSC1 1.2415 3.3455 -1.7087 1.0996
NCI-H1299 GDSC1 1.2511 3.2179 -1.6559 0.87
NCI-H2172 GDSC1 1.252 2.7753 -1.4939 0.3302
PC-14 GDSC1 1.2539 2.681 -1.4602 0.2487
NCI-H2029 GDSC1 1.257 3.1463 -1.6266 0.7517
EPLC-272H GDSC1 1.2596 3.2888 -1.6793 0.9585
ChaGo-K-1 GDSC1 1.2617 2.9075 -1.5373 0.4464
NCI-H187 GDSC1 1.2639 2.5714 -1.4191 0.1639
HCC15 GDSC1 1.2706 4.6037 -2.2124 3.8083
NCI-H2369 GDSC1 1.2793 3.0815 -1.5936 0.6178
NCI-H2066 GDSC1 1.2816 2.9806 -1.5559 0.4928
NCI-H1048 GDSC1 1.2945 2.9944 -1.5559 0.4858
NCI-H1836 GDSC1 1.3023 2.8372 -1.497 0.3176
NCI-H524 GDSC1 1.3176 3.2911 -1.656 0.8196
NCI-H441 GDSC1 1.3195 3.2061 -1.6235 0.6971
NCI-H1563 GDSC1 1.3247 3.0262 -1.5558 0.4693
Lu-165 GDSC1 1.3419 3.2911 -1.646 0.7644
Calu-3 GDSC1 1.3444 3.2199 -1.6186 0.6634
DMS 273 GDSC1 1.3468 3.1679 -1.5986 0.5932
NCI-H1993 GDSC1 1.3478 3.2637 -1.6334 0.714
NCI-H520 GDSC1 1.3525 3.3776 -1.674 0.8639
NCI-H2804 GDSC1 1.3593 4.0007 -1.9149 1.9726
NCI-H146 GDSC1 1.3654 3.5992 -1.7531 1.1833
NCI-H82 GDSC1 1.374 2.8555 -1.4773 0.2457
NCI-H2461 GDSC1 1.3766 4.0127 -1.9116 1.9353
NCI-H322M GDSC1 1.38 3.8833 -1.8581 1.6608
HCC366 GDSC1 1.3985 3.8848 -1.8503 1.6025
SBC-3 GDSC1 1.4031 3.3348 -1.6375 0.6918
NCI-H1648 GDSC1 1.4104 3.5362 -1.7099 0.9618
COR-L88 GDSC1 1.415 3.2877 -1.6154 0.6086
NCI-H2135 GDSC1 1.4285 2.8775 -1.4654 0.2048
CAL-12T GDSC1 1.4489 3.4766 -1.6716 0.7847
HOP-62 GDSC1 1.4605 3.7781 -1.7811 1.2204
COR-L321 GDSC1 1.4731 3.0734 -1.517 0.3002
NCI-H2869 GDSC1 1.4765 3.9686 -1.8483 1.512
NCI-H1703 GDSC1 1.4792 3.3546 -1.6147 0.5689
NCI-H2023 GDSC1 1.481 3.2253 -1.5675 0.4267
NCI-H358 GDSC1 1.4881 3.397 -1.6266 0.6024
PaCa-3 GDSC1 1.4888 3.7377 -1.7535 1.0773
Calu-6 GDSC1 1.4923 3.0876 -1.5149 0.2885
NCI-H727 GDSC1 1.5018 3.5339 -1.6714 0.748
Lu-99A GDSC1 1.5051 3.6416 -1.7103 0.8907
NCI-H661 GDSC1 1.5256 3.6789 -1.7158 0.897
NCI-H596 GDSC1 1.5389 3.4816 -1.6375 0.6085
COR-L32 GDSC1 1.5537 3.5019 -1.6391 0.6051
NCI-H1838 GDSC1 1.5633 3.6128 -1.676 0.7238
NCI-H2731 GDSC1 1.5653 3.8432 -1.7614 1.0473
LC-2/ad GDSC1 1.566 3.3507 -1.5801 0.4222
NCI-H1355 GDSC1 1.574 3.8778 -1.7709 1.0792
ABC-1 GDSC1 1.5811 3.7592 -1.7232 0.8844
Lu-135 GDSC1 1.5887 3.5746 -1.6519 0.6265
NCI-H3255 GDSC1 1.6015 3.2783 -1.5415 0.3105
NCI-H2810 GDSC1 1.6021 3.793 -1.7272 0.8845
NCI-H2009 GDSC1 1.6039 3.2866 -1.5435 0.3143
SK-LU-1 GDSC1 1.6045 3.5742 -1.6456 0.5969
NCI-H1869 GDSC1 1.6566 3.5128 -1.6036 0.4454
NCI-H1693 GDSC1 1.6587 3.3609 -1.5494 0.3081
NCI-H1666 GDSC1 1.6596 3.5953 -1.6319 0.5253
NCI-H1944 GDSC1 1.6599 4.093 -1.8166 1.1987
NCI-H2818 GDSC1 1.6616 3.4264 -1.5712 0.3587
NCI-H2085 GDSC1 1.6656 3.8124 -1.7087 0.7728
NCI-H1581 GDSC1 1.6751 3.1908 -1.4853 0.1766
Ms-1 GDSC1 1.6905 3.3292 -1.527 0.2495
RERF-LC-KJ GDSC1 1.6906 3.1034 -1.4506 0.1215
SBC-1 GDSC1 1.6909 3.4187 -1.5578 0.3158
NCI-H1915 GDSC1 1.6913 3.1976 -1.4819 0.1674
EKVX GDSC1 1.693 9.7533 -4.3317 15.5541
NCI-H1623 GDSC1 1.6932 3.711 -1.6607 0.5955
NCI-H23 GDSC1 1.7084 3.7472 -1.6679 0.6098
SW1271 GDSC1 1.7106 3.9349 -1.7359 0.8408
NCI-H2347 GDSC1 1.7125 4.0234 -1.7682 0.9606
NCI-H1755 GDSC1 1.7357 4.2779 -1.8551 1.2981
Lu-65 GDSC1 1.7441 3.5369 -1.5796 0.3471
NCI-H2342 GDSC1 1.7581 3.8188 -1.6745 0.6033
NCI-H522 GDSC1 1.7657 3.6287 -1.6038 0.3985
SK-MES-1 GDSC1 1.7686 3.6864 -1.6231 0.4479
DMS 53 GDSC1 1.7892 3.6682 -1.609 0.4021
NCI-H2110 GDSC1 1.8045 3.8718 -1.6757 0.5821
COR-L105 GDSC1 1.8163 3.9249 -1.6904 0.6211
NCI-H1437 GDSC1 1.8308 3.6004 -1.5701 0.2952
HCC827 GDSC1 1.8763 3.8174 -1.6292 0.4176
NCI-H1341 GDSC1 1.9519 3.7124 -1.5654 0.2484
IST-SL2 GDSC1 1.955 4.5998 -1.8849 1.2379
SW1573 GDSC1 1.9658 4.6256 -1.8902 1.2508
NCI-H3122 GDSC1 2.1092 4.0653 -1.6305 0.3335
VMRC-LCD GDSC1 2.1265 4.1261 -1.6454 0.3606
RERF-LC-Sq1 GDSC1 2.139 4.5371 -1.7869 0.7475
LC-1/sq GDSC1 2.3335 4.7849 -1.8011 0.6852
A-549 GDSC1 2.3393 4.211 -1.5989 0.2092
EMC-BAC-1 GDSC1 2.5325 4.9143 -1.772 0.5107
⏷ Show the Full List of 172 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 0.9436 5.9995 -3.0428 9.9025
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-6 GDSC1 -0.4385 1.5647 -1.8499 4.9207
KYSE-450 GDSC1 -0.336 2.0053 -1.9917 5.7149
OE33 GDSC1 0.709 3.8935 -2.2119 4.8356
EC-GI-10 GDSC1 0.8731 2.8311 -1.6705 1.2843
TE-4 GDSC1 0.9418 3.2143 -1.7931 1.8393
TE-10 GDSC1 1.08 3.2351 -1.737 1.3883
TE-5 GDSC1 1.1512 3.2877 -1.7258 1.262
TE-9 GDSC1 1.1654 2.5469 -1.4458 0.2471
OE19 GDSC1 1.1811 2.5841 -1.453 0.258
KYSE-180 GDSC1 1.2691 3.0569 -1.5886 0.607
COLO 680N GDSC1 1.3313 2.6129 -1.4096 0.1327
KYSE-510 GDSC1 1.3699 3.2803 -1.6307 0.6894
T.T GDSC1 1.3916 3.1794 -1.5852 0.5243
KYSE-150 GDSC1 1.3953 2.852 -1.4684 0.2206
TE-11 GDSC1 1.4632 2.9255 -1.4695 0.203
TE-1 GDSC1 1.5656 3.6531 -1.6899 0.772
TE-8 GDSC1 1.6003 3.8717 -1.7575 1.0041
KYSE-70 GDSC1 1.612 3.0248 -1.4512 0.1372
OE21 GDSC1 1.6809 3.6252 -1.6345 0.522
KYSE-520 GDSC1 1.7891 3.9419 -1.7072 0.6908
TE-15 GDSC1 1.9539 3.9562 -1.6493 0.437
KYSE-270 GDSC1 2.0008 3.9377 -1.6255 0.3602
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHOS-2 GDSC1 0.4979 3.9548 -2.3681 6.3714
TOV-112D GDSC1 0.553 8.104 -4.3315 18.571
IGROV-1 GDSC1 0.7123 2.9517 -1.7972 2.176
OVCAR-8 GDSC1 0.8443 3.2943 -1.8747 2.4374
OVISE GDSC1 0.8832 2.1789 -1.4207 0.2964
OAW42 GDSC1 0.8933 1.8776 -1.3138 0.0812
OV56 GDSC1 0.8978 1.9554 -1.3383 0.1156
TOV-21G GDSC1 0.9354 3.6049 -1.9598 2.8065
OC 314 GDSC1 1.1059 2.4875 -1.4468 0.2713
TYK-nu GDSC1 1.1178 2.9439 -1.608 0.7823
EFO-27 GDSC1 1.1802 2.9645 -1.5901 0.6701
OVCAR-5 GDSC1 1.1985 3.0982 -1.6326 0.818
OVCAR-3 GDSC1 1.2179 3.2084 -1.6663 0.9387
FU-OV-1 GDSC1 1.2254 3.0767 -1.6135 0.7251
DOV13 GDSC1 1.2662 3.0129 -1.5737 0.5584
Caov-4 GDSC1 1.2788 3.5828 -1.7849 1.4121
OVKATE GDSC1 1.3211 3.1265 -1.5936 0.5918
JHOS-4 GDSC1 1.3311 3.1429 -1.5956 0.5927
Kuramochi GDSC1 1.3447 3.3874 -1.681 0.8974
ES-2 GDSC1 1.3506 2.7692 -1.4559 0.2089
OVK18 GDSC1 1.4749 2.9965 -1.4896 0.2394
EFO-21 GDSC1 1.4877 3.109 -1.524 0.3114
OVTOKO GDSC1 1.5798 3.5428 -1.6438 0.6052
OV-90 GDSC1 1.6089 3.3718 -1.5715 0.3809
OVCAR-4 GDSC1 1.665 4.0567 -1.8006 1.1273
A2780 GDSC1 1.8776 3.5939 -1.5512 0.2422
SK-OV-3 GDSC1 1.9019 3.4584 -1.4969 0.146
OAW28 GDSC1 1.9608 4.4452 -1.8242 0.9938
RMG-I GDSC1 1.9718 4.4329 -1.8151 0.9521
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-3 GDSC1 -0.2397 1.962 -1.9053 4.8085
Hs 766T GDSC1 0.2462 2.8407 -2.0079 4.4023
Capan-2 GDSC1 0.2645 4.3027 -2.6859 9.206
HuP-T3 GDSC1 0.3134 3.1949 -2.1301 5.1149
MZ-PC-1 GDSC1 0.3245 3.2012 -2.1262 5.0624
MIA PaCa-2 GDSC1 0.5005 3.6522 -2.2264 5.3745
SUIT-2 GDSC1 0.8059 2.4263 -1.5424 0.7639
SU.86.86 GDSC1 0.9143 2.6962 -1.5995 0.9142
AsPC-1 GDSC1 0.9227 3.7203 -2.0159 3.1698
KP-2 GDSC1 0.9397 2.1293 -1.3828 0.1856
KP-4 GDSC1 0.9401 2.5763 -1.5432 0.6634
YAPC GDSC1 0.9674 2.0984 -1.3624 0.1392
Panc 10.05 GDSC1 1.197 3.0758 -1.6248 0.7887
Panc 02.03 GDSC1 1.228 2.9636 -1.5707 0.5713
PSN1 GDSC1 1.2765 2.8667 -1.5171 0.3812
QGP-1 GDSC1 1.3338 2.679 -1.4311 0.1673
PL4 GDSC1 1.3354 3.0176 -1.5486 0.4427
Panc 08.13 GDSC1 1.3602 2.9846 -1.5275 0.3719
PaTu 8902 GDSC1 1.4254 2.5386 -1.3533 0.0526
PaTu 8988t GDSC1 1.4419 2.7958 -1.4329 0.145
HPAF-II GDSC1 1.4486 3.7076 -1.759 1.1352
BxPC-3 GDSC1 1.4517 3.5006 -1.6794 0.8116
SW1990 GDSC1 1.5422 3.5079 -1.6458 0.6338
Panc 03.27 GDSC1 1.5695 3.1272 -1.5008 0.2332
KP-1N GDSC1 1.6083 3.5853 -1.6481 0.6031
CFPAC-1 GDSC1 1.676 3.3632 -1.5439 0.2898
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 1.3366 3.0437 -1.5575 0.4684
NCI-H2452 GDSC1 1.392 3.2115 -1.5967 0.5606
IST-Mes1 GDSC1 1.5566 3.4689 -1.626 0.5616
NCI-H28 GDSC1 1.7503 3.4939 -1.5623 0.3052
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1 -0.838 1.3411 -2.0385 7.6187
22Rv1 GDSC1 0.8965 3.985 -2.1458 4.0379
DU145 GDSC1 1.3595 3.5332 -1.7303 1.089
LNCaP clone FGC GDSC1 1.6188 3.5711 -1.6389 0.5681
PC-3 GDSC1 2.0258 4.086 -1.6683 0.4559
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 1.6522 3.5881 -1.6322 0.5298
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 783 GDSC1 -1.7285 -0.4909 -1.9748 10.8126
SK-MEL-5 GDSC1 -0.8856 1.4506 -2.1314 8.5107
WM278 GDSC1 0.3096 3.8774 -2.4527 7.4261
SK-MEL-28 GDSC1 0.5159 1.5614 -1.3396 0.241
UACC-62 GDSC1 0.6396 2.0517 -1.47 0.6031
COLO 800 GDSC1 0.6449 4.5907 -2.5723 7.4512
LB2518-MEL GDSC1 0.7498 2.0602 -1.429 0.3863
LB373-MEL-D GDSC1 0.7535 2.2112 -1.4831 0.57
SK-MEL-31 GDSC1 0.762 2.3488 -1.5314 0.7545
M14 GDSC1 0.854 2.8585 -1.6903 1.404
SK-MEL-30 GDSC1 0.8838 2.2256 -1.4371 0.3415
WM115 GDSC1 0.9029 2.3211 -1.4641 0.4124
SK-MEL-2 GDSC1 0.9461 2.1105 -1.374 0.1663
LOX-IMVI GDSC1 0.9528 2.8076 -1.6259 0.9953
UACC-257 GDSC1 0.9537 2.6461 -1.5638 0.7335
WT2-iPS GDSC1 0.9565 2.2826 -1.43 0.2893
A101D GDSC1 0.965 4.2253 -2.2138 4.3523
SK-MEL-3 GDSC1 0.9783 2.599 -1.5361 0.6102
SH-4 GDSC1 1.0162 10.3897 -5.1145 20.9693
COLO 679 GDSC1 1.0228 2.8981 -1.6306 0.9533
Mel Ho GDSC1 1.0236 2.4811 -1.4753 0.3835
CP66-MEL GDSC1 1.0582 2.7908 -1.575 0.6992
G-mel GDSC1 1.0605 2.7598 -1.5626 0.651
Mel JuSo GDSC1 1.0629 2.6767 -1.5309 0.5374
MZ-MEL-7 GDSC1 1.0886 2.848 -1.584 0.7113
IGR-37 GDSC1 1.0957 2.3472 -1.4019 0.1774
Hs 938.T GDSC1 1.1137 2.907 -1.5958 0.7381
MeWo GDSC1 1.114 2.7567 -1.54 0.5371
RVH-421 GDSC1 1.1245 2.7223 -1.5234 0.4767
SK-MEL-1 GDSC1 1.1275 2.7457 -1.5307 0.4985
IPC-298 GDSC1 1.1278 2.5276 -1.4527 0.2772
GAK GDSC1 1.1506 2.5746 -1.4608 0.2881
A-375 GDSC1 1.1643 2.8471 -1.5532 0.5512
CHL-1 GDSC1 1.1749 2.9991 -1.6052 0.7294
WM793 GDSC1 1.2024 2.813 -1.526 0.4433
Hs 940.T GDSC1 1.2635 3.1436 -1.6229 0.7334
COLO 829 GDSC1 1.2757 3.1644 -1.6258 0.7354
MMAc-SF GDSC1 1.2768 2.5384 -1.4034 0.1348
CP50-MEL-B GDSC1 1.2837 2.9385 -1.54 0.4433
VMRC-MELG GDSC1 1.2844 2.9819 -1.5553 0.4894
G-361 GDSC1 1.3175 2.7872 -1.474 0.2576
WM35 GDSC1 1.3629 3.7395 -1.8089 1.4407
451Lu GDSC1 1.4206 3.2196 -1.5885 0.5187
COLO 792 GDSC1 1.4723 3.1018 -1.5272 0.3248
WM1552C GDSC1 1.4916 3.1594 -1.5403 0.3497
IST-MEL1 GDSC1 1.5062 3.8428 -1.7863 1.2025
HT-144 GDSC1 1.5238 2.8804 -1.4331 0.1284
A-431 GDSC1 1.599 3.482 -1.6144 0.504
SK-MEL-24 GDSC1 1.6361 3.4951 -1.605 0.4588
A-388 GDSC1 1.6413 3.5183 -1.6113 0.4743
DJM-1 GDSC1 1.6507 3.4741 -1.592 0.4167
HMV-II GDSC1 1.8065 3.9076 -1.6879 0.6187
MZ-MEL-2 GDSC1 2.036 4.0182 -1.6408 0.383
EquiPSC Line K2 GDSC1 1.6447 4.3707 -1.9314 1.7357
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 1.1313 2.7393 -1.5269 0.4842
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh30 GDSC1 0.2423 6.2504 -3.6492 15.6579
SW982 GDSC1 0.2974 2.2094 -1.696 2.2088
HT-1080 GDSC1 0.3027 5.5043 -3.2408 12.8996
SW684 GDSC1 0.6229 2.6129 -1.7002 1.7445
GCT GDSC1 0.6242 3.8937 -2.2623 5.3554
Rh18 GDSC1 0.7352 2.3555 -1.5454 0.8372
MES-SA GDSC1 0.8002 2.396 -1.5332 0.731
Hs 633.T GDSC1 0.9097 2.597 -1.5636 0.7668
KYM-1 GDSC1 0.9251 2.1747 -1.4037 0.2368
RKN GDSC1 0.9298 2.494 -1.5167 0.5728
EW-8 GDSC1 1.0142 2.5718 -1.5118 0.5026
SK-LMS-1 GDSC1 1.03 3.2546 -1.7678 1.5984
SK-UT-1 GDSC1 1.1798 3.1091 -1.6446 0.8806
Rh41 GDSC1 1.3236 3.1383 -1.5969 0.6016
STS-0421 GDSC1 1.5379 3.7272 -1.7289 0.9387
MFH-ino GDSC1 1.5512 3.2651 -1.5553 0.3634
RD GDSC1 1.5677 3.836 -1.7576 1.0302
A-204 GDSC1 1.5801 4.4561 -1.9954 2.1288
VA-ES-BJ GDSC1 1.7057 3.2295 -1.4877 0.1735
SW872 GDSC1 1.755 3.8272 -1.6788 0.6184
G-401 GDSC1 2.161 4.3205 -1.7008 0.483
G-402 GDSC1 2.3856 4.3467 -1.6287 0.2485
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUM-1 GDSC1 -0.6096 1.9813 -2.1791 7.9655
SNU-16 GDSC1 0.2058 2.3148 -1.7931 3.0052
KATO III GDSC1 0.4235 3.165 -2.0498 4.3162
MKN45 GDSC1 0.4508 1.6397 -1.3933 0.4481
SCH GDSC1 0.6282 2.1017 -1.4938 0.7087
23132/87 GDSC1 0.8711 2.3105 -1.4727 0.4577
HGC-27 GDSC1 0.9127 2.5656 -1.5505 0.712
SNU-5 GDSC1 1.0298 2.5248 -1.4886 0.42
SNU-1 GDSC1 1.0449 2.7932 -1.5814 0.7334
MKN1 GDSC1 1.1165 2.6469 -1.4993 0.4073
Fu97 GDSC1 1.1622 2.6962 -1.4995 0.3857
NUGC-3 GDSC1 1.1849 2.996 -1.5999 0.7028
HSC-39 GDSC1 1.1913 3.1283 -1.647 0.8813
ECC10 GDSC1 1.3053 13.4139 -6.3876 24.9615
NCI-N87 GDSC1 1.3226 3.5858 -1.7666 1.2837
SK-GT-2 GDSC1 1.3791 3.5936 -1.745 1.1355
NUGC-4 GDSC1 1.3868 3.5638 -1.7303 1.0659
TGBC11TKB GDSC1 1.3975 3.3464 -1.644 0.7189
RF-48 GDSC1 1.4621 3.3908 -1.6346 0.6446
MKN7 GDSC1 1.4785 3.3137 -1.6001 0.5236
RERF-GC-1B GDSC1 1.6389 3.8253 -1.7242 0.8472
Hs 746.T GDSC1 1.6719 3.5449 -1.6092 0.454
TMK-1 GDSC1 1.9345 3.6488 -1.5498 0.2243
SNG-M GDSC1 1.601 3.2876 -1.5449 0.3186
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHT-101 GDSC1 -0.3177 1.8618 -1.9099 5.0473
CAL-62 GDSC1 0.7565 6.4561 -3.3852 12.5752
ASH-3 GDSC1 0.7955 2.4057 -1.5389 0.7581
CGTH-W-1 GDSC1 0.9194 2.6291 -1.5717 0.7921
B-CPAP GDSC1 1.024 2.6383 -1.5323 0.5664
K5 GDSC1 1.0338 2.8581 -1.6106 0.8594
WRO GDSC1 1.1386 3.0137 -1.6257 0.8367
TT GDSC1 1.154 3.0135 -1.6192 0.7989
IHH-4 GDSC1 1.1684 11.9096 -5.7489 23.1011
ML-1 [Human leukemia] GDSC1 1.2298 3.1816 -1.6511 0.8673
KMH-2 GDSC1 1.2583 2.9923 -1.5693 0.5485
FTC-133 GDSC1 1.3594 2.7101 -1.4327 0.1637
TT2609-C02 GDSC1 1.5165 3.3239 -1.5893 0.4715
8305C GDSC1 1.5561 3.0924 -1.4936 0.223
HTC-C3 GDSC1 1.7844 3.6064 -1.5891 0.3546
8505C GDSC1 1.8216 3.7115 -1.6122 0.3969
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-27 GDSC1 0.1522 8.9395 -5.0452 23.1373
PCI-30 GDSC1 0.3882 2.9645 -1.9797 3.9087
CAL-33 GDSC1 0.4028 2.5771 -1.7991 2.683
NCI-H3118 GDSC1 0.5319 5.9512 -3.2965 12.6187
OSC-20 GDSC1 0.5669 4.6811 -2.6649 8.2813
UPCI-SCC-090 GDSC1 0.7845 3.4161 -1.9581 3.0387
BICR 22 GDSC1 0.8671 2.2675 -1.4586 0.4146
HSC-2 GDSC1 0.8946 3.4527 -1.9161 2.6073
HO-1-u-1 GDSC1 0.9116 2.9807 -1.7126 1.4523
JHU-022 GDSC1 0.9462 3.8797 -2.0724 3.4824
Detroit 562 GDSC1 0.9517 2.7867 -1.6183 0.9628
HSC-4 GDSC1 1.0012 2.8056 -1.6044 0.8604
PCI-04B GDSC1 1.0564 4.3845 -2.2332 4.31
PCI-38 GDSC1 1.1084 3.0385 -1.6479 0.9533
SCC-4 GDSC1 1.1283 2.6374 -1.4914 0.3787
DOK GDSC1 1.1658 3.6681 -1.8714 1.9791
JHU-029 GDSC1 1.1725 4.3255 -2.1444 3.5524
BB49-HNC GDSC1 1.1968 3.3305 -1.7224 1.2022
BB30-HNC GDSC1 1.2151 3.8825 -1.9356 2.2655
HSC-3 GDSC1 1.2394 2.7864 -1.5025 0.3584
SCC-9 GDSC1 1.2403 2.9295 -1.5534 0.5076
Ca9-22 GDSC1 1.2635 3.3488 -1.7006 1.0448
OSC-19 GDSC1 1.2828 2.8778 -1.5186 0.3827
SKN-3 GDSC1 1.2899 3.2062 -1.6356 0.762
PCI-06A GDSC1 1.3451 3.315 -1.6536 0.7906
KON GDSC1 1.347 3.2675 -1.6352 0.7209
BICR 10 GDSC1 1.3475 2.9527 -1.521 0.3602
HO-1-N-1 GDSC1 1.4205 3.2824 -1.6114 0.5919
PE/CA-PJ15 GDSC1 1.4237 3.1185 -1.5511 0.4076
PCI-15A GDSC1 1.4735 3.3074 -1.5998 0.5252
BICR 78 GDSC1 1.5203 4.1685 -1.9076 1.7525
SAT [Human HNSCC] GDSC1 1.5422 4.3916 -1.9871 2.1308
SCC-25 GDSC1 1.6039 3.7018 -1.6925 0.7559
LB771-HNC GDSC1 1.6212 3.9748 -1.7879 1.1108
SCC-15 GDSC1 1.6803 3.4026 -1.556 0.3155
SAS GDSC1 1.8068 3.7347 -1.6259 0.4387
BHY GDSC1 1.8192 3.3314 -1.4827 0.1419
KOSC-2 GDSC1 1.8925 4.4284 -1.8461 1.1302
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC1 0.3322 2.327 -1.7283 2.3537
639V GDSC1 0.7559 2.0977 -1.4403 0.4189
SW1710 GDSC1 0.8009 3.6806 -2.0646 3.6864
KU-19-19 GDSC1 0.8669 2.1823 -1.4281 0.3238
CAL-29 GDSC1 0.96 2.4514 -1.4891 0.4599
RT-4 GDSC1 1.0499 2.641 -1.523 0.5186
HT-1197 GDSC1 1.1168 3.485 -1.8202 1.7677
RT-112 GDSC1 1.1348 2.9614 -1.6075 0.7678
HT-1376 GDSC1 1.1889 2.9353 -1.5758 0.6133
5637 GDSC1 1.1914 3.0928 -1.6335 0.8271
UM-UC-3 GDSC1 1.2921 4.5672 -2.1853 3.608
T24 GDSC1 1.3691 3.8778 -1.8609 1.6863
647V GDSC1 1.4935 2.9298 -1.4603 0.1782
TCCSUP GDSC1 1.5986 3.2277 -1.525 0.2744
J82 GDSC1 1.6308 3.3804 -1.5664 0.3592
SW780 GDSC1 1.6634 3.74 -1.6829 0.6851
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NT2-D1 GDSC1 0.2724 2.577 -1.8724 3.4106
HeLa GDSC1 0.3792 1.7424 -1.4627 0.7972
DSH1 GDSC1 0.7163 2.8701 -1.761 1.9609
SW954 GDSC1 0.8166 3.9015 -2.1536 4.2365
Ca Ski GDSC1 0.8268 3.4141 -1.9348 2.8259
JEG-3 GDSC1 0.913 3.0528 -1.7411 1.5973
BPH-1 GDSC1 1.0292 3.7693 -1.9813 2.7913
OV17R GDSC1 1.0514 3.6217 -1.908 2.3322
MS751 GDSC1 1.1072 2.6713 -1.5116 0.4493
OVCA433 GDSC1 1.1472 3.9591 -2.0013 2.7335
SiHa GDSC1 1.166 2.5475 -1.4457 0.2468
SKG-IIIa GDSC1 1.2156 2.8248 -1.5252 0.434
OVCA420 GDSC1 1.273 3.2156 -1.646 0.8143
LB831-BLC GDSC1 1.3014 3.8302 -1.8731 1.8247
JAR GDSC1 1.3193 2.9677 -1.5369 0.4166
OMC-1 [Human cervical carcinoma] GDSC1 1.3318 3.3951 -1.6893 0.9408
C-33 A GDSC1 1.3612 3.4089 -1.6823 0.8897
CAL-39 GDSC1 1.3901 3.6664 -1.7684 1.2283
TC-YIK GDSC1 1.3924 3.703 -1.7816 1.2854
SKN GDSC1 1.4073 4.1143 -1.9383 2.0377
SW962 GDSC1 1.4089 3.5271 -1.707 0.9515
JHOS-3 GDSC1 1.4542 3.4567 -1.662 0.746
HEC-1 GDSC1 1.5083 3.0771 -1.5055 0.2622
HT-3 GDSC1 1.5344 3.6196 -1.6901 0.7939
ME-180 GDSC1 1.5543 3.8447 -1.7666 1.0777
DoTc2 4510 GDSC1 1.5544 3.2893 -1.5627 0.381
UWB1.289 GDSC1 1.6125 4.1145 -1.8453 1.3661
SiSo GDSC1 1.6371 3.9777 -1.7823 1.0749
ACC-OV7 GDSC1 1.6821 4.224 -1.8575 1.3562
SW756 GDSC1 1.6873 3.1873 -1.4798 0.1649
OVMIU GDSC1 1.6884 3.9324 -1.744 0.8861
HEY GDSC1 1.7754 3.7779 -1.6532 0.5295
PWR-1E GDSC1 1.7834 3.9179 -1.7006 0.6726
KGN GDSC1 1.7902 3.7736 -1.646 0.5016
PEO1 GDSC1 1.8482 3.7051 -1.6002 0.357
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug

References

1 Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP. J Med Chem. 2013 Nov 14;56(21):8931-42.