Details of the Drug

General Information of Drug (ID: DM826SW)

Drug Name
PF-04236921
Indication
Disease Entry ICD 11 Status REF
Crohn disease DD70 Phase 2 [1]
Systemic lupus erythematosus 4A40.0 Phase 2 [2]
Cross-matching ID
TTD ID
D06NXG
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin (IL) TTF6I40 NOUNIPROTAC Inhibitor [3]
Interleukin-6 (IL6) TTT1V78 IL6_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Crohn disease
ICD Disease Classification DD70
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin-6 (IL6) DTT IL6 8.08E-01 -0.77 -1.15
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 ClinicalTrials.gov (NCT01405196) Subcutaneous Treatment In Randomized Subjects To Evaluate Safety And Efficacy In Generalized Lupus Erythematosus. U.S. National Institutes of Health.
3 US patent application no. 2010,0158,905, Combination therapy of arthritis with tranilast.