Details of the Drug

General Information of Drug (ID: DM82SJP)

Drug Name
BMS270394
Synonyms BMS 961; BMS-270394; BMS 270394
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 399.5
Logarithm of the Partition Coefficient (xlogp) 4.9
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C23H26FNO4
IUPAC Name
3-fluoro-4-[[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)acetyl]amino]benzoic acid
Canonical SMILES
CC1(CCC(C2=C1C=CC(=C2)[C@H](C(=O)NC3=C(C=C(C=C3)C(=O)O)F)O)(C)C)C
InChI
InChI=1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29)/t19-/m1/s1
InChIKey
AANFHDFOMFRLLR-LJQANCHMSA-N
Cross-matching ID
PubChem CID
445455
TTD ID
D0M3LK

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Retinoic acid receptor gamma (RARG) TT1Q3IE RARG_HUMAN Agonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Retinoic acid receptor gamma (RARG) DTT RARG 5.43E-04 -0.14 -0.37
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 147 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 5.7662 9.5063 4.0765 8.823
MEC1 CTRP2 5.8155 8.134 4.8032 5.6762
JM1 CTRP2 5.6155 8.6086 4.3894 7.8308
EoL-1 CTRP2 1.0563 3.8401 1.0078 33.3913
MV4-11 CTRP2 1.8843 4.6498 1.7952 28.0158
OCI-AML-3 CTRP2 2.3162 4.1047 2.2996 24.8934
SIG-M5 CTRP2 2.7536 4.3419 2.7385 21.9741
HuT 78 CTRP2 3.4877 6.5467 3.1025 18.4033
THP-1 CTRP2 4.008 8.9981 2.6531 18.6935
SK-MM-2 CTRP2 4.1051 14.2254 0.2434 26.6584
KMS-28BM CTRP2 4.1514 8.1813 3.1648 16.325
HH [Human lymphoma] CTRP2 4.3457 10.0381 2.501 18.4325
MOLM-13 CTRP2 4.5142 7.4971 3.8361 12.7319
OCI-AML-2 CTRP2 4.6105 7.5179 3.9266 12.1218
RPMI-8226 CTRP2 4.6277 7.5698 3.9217 12.0958
NU-DHL-1 CTRP2 4.7559 7.6155 4.0327 11.3233
KMS-34 CTRP2 4.812 7.8649 3.9771 11.4029
KMS-12-BM CTRP2 4.9353 6.7741 4.5786 8.7028
Pfeiffer CTRP2 5.0129 7.7632 4.2246 9.9047
JVM-3 CTRP2 5.034 9.7252 3.3064 13.5995
OCI-Ly3 CTRP2 5.1096 10.2801 3.1047 14.2481
GA-10 CTRP2 5.1367 8.4257 4.0328 10.3865
EM-2 CTRP2 5.2179 8.3351 4.1539 9.6995
NCO2 CTRP2 5.22 7.2834 4.6518 7.6667
MOLT-13 CTRP2 5.2429 9.3148 3.7012 11.5082
EB1 CTRP2 5.2742 8.6036 4.0774 9.8846
Ri-1 CTRP2 5.295 8.6632 4.0679 9.8762
L-540 CTRP2 5.302 6.7497 4.9728 6.1783
Mino CTRP2 5.3397 7.729 4.5611 7.743
Daudi CTRP2 5.4032 6.6055 5.1394 5.2553
SUP-M2 CTRP2 5.4659 7.1115 4.9758 5.7489
MOLM-6 CTRP2 5.4765 8.2709 4.4285 7.9741
MOLT-3 CTRP2 5.4994 6.1827 5.4068 3.9622
SU-DHL-6 CTRP2 5.5274 7.4307 4.8843 5.9755
RL CTRP2 5.5557 8.7271 4.2768 8.4299
BL-70 CTRP2 5.5625 6.4739 5.3609 3.9625
PF-382 CTRP2 5.5833 7.9064 4.7059 6.5843
ST486 CTRP2 5.6288 7.6131 4.8915 5.7128
OCI-M1 CTRP2 5.6405 7.1342 5.1348 4.6815
OPM-2 CTRP2 5.6658 7.3982 5.0308 5.0523
NALM-6 CTRP2 5.6737 7.1976 5.1358 4.6006
697 CTRP2 5.6798 7.9397 4.778 6.0712
BV-173 CTRP2 5.692 7.2001 5.1518 4.4925
SU-DHL-4 CTRP2 5.7274 6.9823 5.2908 3.8377
P12-Ichikawa CTRP2 5.7436 8.0613 4.7755 5.9439
DB CTRP2 5.802 6.9194 5.3915 3.2509
KE-37 CTRP2 5.8038 7.7261 4.9955 4.8964
Peer CTRP2 5.8083 7.6512 5.0367 4.7148
SU-DHL-8 CTRP2 5.8122 7.3796 5.1746 4.1302
M-07e CTRP2 5.8147 9.6266 4.0585 8.7996
HL-60 CTRP2 5.8615 9.8752 3.9745 9.0565
Ci-1 CTRP2 5.8661 7.8469 4.9906 4.7859
MJ CTRP2 5.8834 11.1123 3.3751 11.5038
HT CTRP2 5.887 9.8792 3.9943 8.9227
JURL-MK1 CTRP2 5.8911 9.1013 4.3863 7.2707
TALL-1 [Human adult T-ALL] CTRP2 5.9199 7.4171 5.2517 3.5804
SET-2 CTRP2 5.9298 6.8227 5.5561 2.2849
SUP-T1 CTRP2 5.9303 7.8501 5.0448 4.4273
NU-DUL-1 CTRP2 5.9555 8.5061 4.7387 5.6622
KMS-20 CTRP2 5.9643 7.5032 5.2473 3.5085
A4/Fukuda CTRP2 5.9666 11.4694 3.2668 11.7834
U-937 CTRP2 5.9833 8.2929 4.8688 5.0606
K-562 CTRP2 5.9916 7.501 5.2716 3.3516
RPMI-8402 CTRP2 6.008 7.1719 5.4501 2.5693
KMS-18 CTRP2 6.0202 8.8416 4.6256 6.0107
KMS-26 CTRP2 6.0212 10.3178 3.8883 9.1016
TF-1 CTRP2 6.0508 7.3355 5.4042 2.6787
RS4;11 CTRP2 6.0522 8.55 4.7981 5.2235
RCH-ACV CTRP2 6.058 9.7908 4.1826 7.798
CA46 CTRP2 6.0794 9.393 4.3992 6.8478
A3/Kawakami CTRP2 6.0911 7.0316 5.5891 1.8253
LP-1 CTRP2 6.0941 8.2756 4.9699 4.4213
Kasumi-2 CTRP2 6.111 8.6987 4.7724 5.2195
Namalwa CTRP2 6.1271 10.3693 3.9505 8.6379
Ki-JK CTRP2 6.137 9.544 4.3711 6.8562
HD-MY-Z CTRP2 6.152 8.1133 5.0982 3.7743
ALL-SIL CTRP2 6.1618 7.4983 5.4128 2.4368
SU-DHL-1 CTRP2 6.1643 8.7179 4.8062 4.9779
HEL 92.1.7 CTRP2 6.1791 7.4462 5.4523 2.2407
MOLT-16 CTRP2 6.1852 9.178 4.5933 5.8328
KMS-11 CTRP2 6.2112 7.6543 5.3739 2.5126
MC116 CTRP2 6.2863 7.3464 5.5823 1.5221
JeKo-1 CTRP2 6.3123 8.1769 5.1923 3.0965
SR CTRP2 6.3233 8.1039 5.2369 2.8925
MOTN-1 CTRP2 6.3267 7.7927 5.3929 2.2392
SUP-HD1 CTRP2 6.3979 10.4173 4.1451 7.324
NOMO-1 CTRP2 6.4213 13.3976 2.677 13.2779
Mono-Mac-1 CTRP2 6.4344 9.3632 4.6978 4.9509
SU-DHL-10 CTRP2 6.4394 7.4491 5.6377 1.0806
KMS-21-BM CTRP2 6.4473 8.2929 5.2357 2.6963
CMK CTRP2 6.4488 8.7663 5.004 3.6521
CML-T1 CTRP2 6.4911 9.0932 4.8744 4.1203
DEL CTRP2 6.5323 9.6834 4.6138 5.1346
KM-H2 CTRP2 6.5334 10.8429 4.0395 7.5245
KHM-1B CTRP2 6.5546 9.7658 4.5899 5.1968
LAMA-84 CTRP2 6.5681 9.2452 4.8567 4.068
SKM-1 CTRP2 6.5689 9.4071 4.7777 4.3936
HuNS1 CTRP2 6.5945 8.2636 5.353 2.0004
P31/FUJ CTRP2 6.5949 11.215 3.9024 7.9871
JJN-3 CTRP2 6.61 8.6246 5.1898 2.6362
F-36P CTRP2 6.6303 9.2135 4.9176 3.7182
L-428 CTRP2 6.6334 9.522 4.7687 4.3269
HDLM-2 CTRP2 6.638 10.3976 4.3405 6.0935
PL21 CTRP2 6.6617 11.9229 3.6024 9.1099
Ku812 CTRP2 6.6888 9.4053 4.866 3.8393
MOLM-16 CTRP2 6.6919 8.6092 5.2532 2.2638
HPB-ALL CTRP2 6.6949 8.7099 5.207 2.4446
REC-1 CTRP2 6.6972 10.2529 4.4563 5.5155
RPMI-6666 CTRP2 6.7152 9.3863 4.8941 3.6837
KE-97 CTRP2 6.7696 12.3168 3.4901 9.3827
KCL-22 CTRP2 6.7732 10.852 4.2177 6.3785
ME1 CTRP2 6.8561 9.6722 4.8543 3.636
SUP-T11 CTRP2 6.8656 9.65 4.8715 3.5523
KMS-27 CTRP2 6.8949 9.1687 5.1215 2.512
SUP-B15 CTRP2 6.9718 8.8215 5.3315 1.6092
NB4 CTRP2 6.9789 11.43 4.0852 6.5924
NCI-H929 CTRP2 7.0237 14.1845 2.7589 11.8715
Karpas-299 CTRP2 7.0552 10.2523 4.7116 3.9253
KMM-1 CTRP2 7.0898 10.3663 4.6804 4.0016
MHH-CALL-3 CTRP2 7.0988 9.7449 4.9818 2.7941
KO52 CTRP2 7.1011 12.9814 3.4123 9.1398
MOLP-8 CTRP2 7.1495 8.6259 5.5167 0.7903
KYO-1 CTRP2 7.1528 9.8583 4.9631 2.7983
MHH-CALL-4 CTRP2 7.179 9.8136 5.0006 2.6203
DND-41 CTRP2 7.1815 9.1105 5.3232 1.4155
OCI-AML-5 CTRP2 7.2082 11.3607 4.2825 5.4358
Jurkat CTRP2 7.2367 10.9972 4.4774 4.6089
MOLP-2 CTRP2 7.2545 9.9436 4.9873 2.579
MM1.S CTRP2 7.2814 8.922 5.4588 0.8684
Hs 611.T CTRP2 7.315 10.1366 4.9353 2.7044
Karpas-422 CTRP2 7.3291 9.0865 5.4135 0.9744
HEL CTRP2 7.3323 9.2544 5.343 1.2038
EHEB CTRP2 7.3417 14.8106 2.6899 11.5993
U266B1 CTRP2 7.4262 10.8543 4.6704 3.5892
P3HR-1 CTRP2 7.5461 9.2618 5.4481 0.7096
Reh CTRP2 7.6303 10.6203 4.904 2.4606
L-363 CTRP2 7.724 9.0088 5.6228 0.2143
GDM-1 CTRP2 7.7375 9.8608 5.2942 1.0295
AMO1 CTRP2 7.7663 8.8011 5.7119 0.08
AML-193 CTRP2 7.8022 8.9786 5.6633 0.1314
Kasumi-1 CTRP2 8.152 9.945 5.4485 0.396
EJM CTRP2 8.1607 19.7179 0.8812 16.6191
Karpas-620 CTRP2 8.186 9.5126 5.6173 0.1142
Granta-519 CTRP2 8.3289 21.8912 -0.065 19.1707
Toledo CTRP2 8.431 10.1667 5.4778 0.2505
OCI-Ly19 CTRP2 8.8106 17.5349 2.409 10.3955
OCI-Ly10 CTRP2 10.6155 22.9875 1.0124 12.6434
⏷ Show the Full List of 147 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 7.0128 11.8857 3.8863 7.3538
TE8 CTRP2 8.5058 19.2601 1.3586 14.5175
TE-11 CTRP2 6.4759 8.036 5.3813 2.0565
KYSE-70 CTRP2 6.4898 10.2517 3.5243 4.3685
TE-5 CTRP2 6.4927 9.0862 4.8791 4.0981
KYSE-180 CTRP2 6.5389 9.2665 4.8246 4.2483
KYSE-140 CTRP2 6.5504 9.9919 4.4748 5.6824
KYSE-150 CTRP2 6.9475 8.4831 5.4701 1.1298
EC-GI-10 CTRP2 6.9541 12.0146 3.7794 7.8872
KYSE-30 CTRP2 6.9713 8.3109 5.5586 0.8031
TE-9 CTRP2 7.0821 9.359 5.1513 2.1603
KYSE-520 CTRP2 7.1085 10.8697 4.4507 4.9014
TE-6 CTRP2 7.1677 10.7697 4.5397 4.4567
TE-14 CTRP2 7.1919 10.8972 4.4949 4.6023
OE21 CTRP2 7.5103 16.7489 1.8593 14.4058
TE-10 CTRP2 7.5923 9.6564 5.307 1.1016
COLO 680N CTRP2 7.5983 9.5466 5.3561 0.9444
TE-1 CTRP2 7.6636 9.3812 5.4548 0.6182
OE19 CTRP2 7.6726 8.8453 5.662 0.1644
KYSE-410 CTRP2 7.7078 9.6385 5.3715 0.8212
KYSE-510 CTRP2 7.7236 12.5687 4.0532 5.622
OE33 CTRP2 8.1396 10.285 5.3121 0.7197
TE-4 CTRP2 8.7063 18.0501 2.0891 11.6954
KYSE-450 CTRP2 9.3588 15.4929 3.713 4.9258
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 10.8876 18.5908 3.1995 5.1536
Panc 02.03 CTRP2 1.2175 2.8478 -2.4629 0.1481
KP-3 CTRP2 6.1454 13.1328 2.584 14.1691
YAPC CTRP2 6.361 9.115 3.9736 2.6832
KP-4 CTRP2 6.4568 8.6146 5.0847 3.3042
Panc 08.13 CTRP2 6.6322 8.4578 5.2854 2.2182
TCC-Pan2 CTRP2 6.8202 10.5092 3.6119 3.5709
Panc 03.27 CTRP2 6.8966 8.3895 5.4829 1.136
Panc 04.03 CTRP2 7.0961 8.9626 5.3406 1.4409
KP-2 CTRP2 7.1417 10.5923 4.6071 4.2226
BxPC-3 CTRP2 7.1795 10.092 4.8703 3.1259
MIA PaCa-2 CTRP2 7.2684 8.8394 5.4871 0.7903
PSN1 CTRP2 7.2825 8.7567 5.5283 0.6556
CFPAC-1 CTRP2 7.4174 9.489 5.287 1.316
Panc 05.04 CTRP2 7.4657 8.8903 4.5873 0.1092
HPAF-II CTRP2 7.5313 10.1482 5.0592 2.0017
AsPC-1 CTRP2 7.6072 10.2156 5.0722 1.8786
SU.86.86 CTRP2 7.6264 8.9033 5.6228 0.2465
Capan-1 CTRP2 7.6385 9.6356 5.3389 0.9668
DAN-G CTRP2 7.6571 9.1954 5.525 0.4442
QGP-1 CTRP2 7.7184 9.2631 5.5253 0.4142
SNU-213 CTRP2 7.7809 9.071 5.6223 0.1981
Capan-2 CTRP2 7.9132 13.0374 3.9558 5.7482
PaTu 8988t CTRP2 7.9353 9.1825 5.6409 0.1328
PK-59 CTRP2 7.9827 9.8804 5.4011 0.5798
L3.3 CTRP2 8.0878 9.2106 5.6855 0.0619
Hs 766T CTRP2 8.173 15.2593 3.0676 8.8466
PaTu 8902 CTRP2 8.2607 9.4632 5.6603 0.063
Panc 10.05 CTRP2 8.2747 10.0098 5.4739 0.3033
SUIT-2 CTRP2 8.288 9.7238 5.581 0.1383
HuP-T3 CTRP2 8.3304 9.9691 5.5103 0.2265
PK-45H CTRP2 8.3321 10.8794 5.1629 1.0052
HPAC CTRP2 8.3376 9.8628 5.5506 0.1669
HuP-T4 CTRP2 8.4548 10.3542 5.419 0.3439
SW1990 CTRP2 8.8759 10.689 5.4592 0.175
SNU-410 CTRP2 9.0579 10.8388 5.4728 0.1296
PaTu 8988s CTRP2 13.1835 49.2084 -9.9155 29.3425
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 9.8293 23.3372 0.313 15.8102
CJM [Human melanoma] CTRP2 6.363 7.4436 5.5892 1.3786
MeWo CTRP2 6.3937 9.7204 4.4888 5.8944
HMCB CTRP2 6.4663 7.6364 5.5666 1.3252
G-361 CTRP2 6.6559 11.2714 3.9214 7.8026
COLO 792 CTRP2 6.6673 8.6555 5.2144 2.4539
Hs 895.T CTRP2 6.8867 9.5475 4.9354 3.2647
UACC-257 CTRP2 6.8869 10.6975 4.3772 5.5383
SK-MEL-3 CTRP2 6.914 10.0885 4.6932 4.2043
Mel Ho CTRP2 7.0094 10.8573 4.3871 5.3085
IPC-298 CTRP2 7.0232 8.4162 5.5406 0.8175
SK-MEL-28 CTRP2 7.0273 7.7964 5.7914 0.1366
SK-MEL-5 CTRP2 7.1192 9.1626 5.2638 1.6959
WM115 CTRP2 7.1281 8.24 5.6647 0.3745
IGR-37 CTRP2 7.1589 9.1874 5.2758 1.6092
Hs 944.T CTRP2 7.1597 9.5481 5.1117 2.2185
WM266-4 CTRP2 7.1609 10.0678 4.8697 3.1526
MDA-MB-435S CTRP2 7.178 10.771 4.546 4.4165
COLO 829 CTRP2 7.2262 9.6608 5.1004 2.1833
Hs 839.T CTRP2 7.2828 8.9199 5.4604 0.8624
Hs 688(A).T CTRP2 7.3822 8.3501 5.7286 0.1376
WM1799 CTRP2 7.3957 9.3426 5.3387 1.1622
SK-MEL-2 CTRP2 7.3992 8.6236 5.6342 0.3128
COLO 800 CTRP2 7.4007 10.6638 4.7435 3.3373
Hs 936.T CTRP2 7.4338 9.9182 5.1062 1.9336
LOX-IMVI CTRP2 7.4531 11.7011 4.2864 5.0692
HT-144 CTRP2 7.4778 9.387 5.3624 1.0174
RVH-421 CTRP2 7.5417 9.0647 5.5251 0.504
A-375 CTRP2 7.6396 9.558 5.3716 0.8679
WT2-iPS CTRP2 7.6716 9.5671 5.3834 0.8114
SK-MEL-1 CTRP2 7.6902 8.8481 5.6677 0.1512
Hs 294T CTRP2 7.6983 8.7834 5.6935 0.1136
WM793 CTRP2 7.7951 9.437 5.4914 0.4565
A101D CTRP2 7.9218 8.9759 5.7071 0.0632
SK-MEL-24 CTRP2 7.9372 9.3827 5.5701 0.2401
A2058 CTRP2 7.9799 8.9242 5.7441 0.0315
WM88 CTRP2 8.0301 12.7522 4.1656 4.7811
K029AX CTRP2 8.0433 11.9464 4.546 3.3256
Mel JuSo CTRP2 8.0624 9.5192 5.5692 0.2057
RPMI-7951 CTRP2 8.2195 9.5477 5.6172 0.1087
SK-MEL-31 CTRP2 8.3522 9.7763 5.586 0.121
Hs 940.T CTRP2 8.3529 20.1828 0.7946 16.5812
SK-MEL-30 CTRP2 8.4508 13.301 4.1714 4.2564
IGR-39 CTRP2 8.6272 14.7455 3.6118 6.1491
Hs 852.T CTRP2 8.6638 10.1101 5.582 0.0812
WM983B CTRP2 10.4348 17.2509 3.5386 4.4537
UACC-62 CTRP2 11.0814 19.8741 2.7392 6.4877
IGR-1 CTRP2 13.1348 27.8286 0.3409 11.6442
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 6.8838 21.5172 -1.0041 24.1186
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-DZ CTRP2 3.7279 7.5976 2.9712 18.2133
NB1 CTRP2 4.838 7.123 4.3319 9.926
IMR-32 CTRP2 5.6963 6.8887 5.3059 3.8486
Kelly CTRP2 5.9501 9.7481 4.1134 8.2985
CHP-212 CTRP2 6.1266 10.5986 3.8354 9.1197
SK-N-FI CTRP2 6.8804 8.3473 5.4924 1.1183
NH-6 CTRP2 6.9982 16.2079 1.734 15.7464
SK-N-SH CTRP2 7.0572 8.7763 5.4016 1.2624
CHP-126 CTRP2 7.5848 11.0376 4.685 3.3353
SK-N-AS CTRP2 7.6523 11.1059 4.6951 3.216
KP-N-SI9s CTRP2 8.2425 9.5344 5.6299 0.0921
KP-N-YN CTRP2 8.6826 19.3426 1.4451 13.9566
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 5.4033 10.3852 3.319 12.7295
SNU-478 CTRP2 6.8217 9.0465 5.1313 2.5717
SNU-1196 CTRP2 6.9764 8.6608 5.407 1.3262
SNU-308 CTRP2 7.3496 11.1584 4.4763 4.4558
HuH-28 CTRP2 7.621 8.818 5.6519 0.1956
HuCC-T1 CTRP2 8.1275 9.574 5.5743 0.1815
SNU-869 CTRP2 8.1589 14.0221 3.6502 6.6103
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-292 clone A141B1 CTRP2 5.9472 11.5622 3.2041 12.0779
TC71 CTRP2 6.1187 7.0101 5.6219 1.6375
SK-ES-1 CTRP2 6.2926 9.2175 4.6596 5.3589
HOS CTRP2 6.3651 7.5785 5.5254 1.6348
A-673 CTRP2 6.7314 10.2371 4.4894 5.3232
SK-N-MC CTRP2 6.7848 10.129 4.5815 4.8587
Hs 822.T CTRP2 6.8873 15.791 1.8545 15.5159
Hs 888.T CTRP2 7.1928 15.1198 2.4246 12.8665
CADO-ES1 CTRP2 7.5068 9.1632 5.4695 0.6744
MHH-ES-1 CTRP2 7.5949 10.8417 4.7817 2.9557
SJSA-1 CTRP2 7.6013 9.7025 5.292 1.142
SaOS-2 CTRP2 7.9587 14.33 3.368 7.9914
CAL-78 CTRP2 8.0892 10.1456 5.3444 0.6647
SW1353 CTRP2 8.3049 9.8155 5.5552 0.1678
MG-63 CTRP2 10.4984 24.4578 0.2331 15.1177
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ZR-75-30 CTRP2 0.7073 2.7329 -2.608 0.7198
HCC1500 CTRP2 5.898 10.4943 3.6963 10.1448
KPL-1 CTRP2 6.2264 11.1201 3.6566 9.675
DU4475 CTRP2 6.2915 7.7755 5.3751 2.3709
SK-BR-3 CTRP2 6.3008 10.7217 3.9159 8.4574
Hs 578T CTRP2 6.3622 10.8641 3.894 8.4363
HCC1428 CTRP2 6.4321 13.9362 2.4167 14.2673
ZR-75-1 CTRP2 6.439 10.6483 3.3022 5.383
BT-20 CTRP2 6.8856 10.3668 4.5378 4.8815
AU565 CTRP2 6.9184 10.5734 4.4605 5.1474
HCC202 CTRP2 6.9188 10.9602 4.2717 5.9217
T-47D CTRP2 7.0246 10.8266 4.4128 5.1806
HCC1937 CTRP2 7.2109 11.2066 4.3589 5.1229
HCC1954 CTRP2 7.2235 8.8109 5.4762 0.8596
BT-549 CTRP2 7.3757 9.18 5.3978 0.9866
MDA-MB-415 CTRP2 7.4232 13.3724 3.4563 8.4465
Hs 578Bst CTRP2 7.475 9.7953 5.1843 1.6148
MDA-MB-231 CTRP2 7.5094 11.0872 4.6143 3.7013
HMC-1-8 CTRP2 7.6288 8.7957 5.663 0.1747
CAL-120 CTRP2 7.7029 9.0045 5.616 0.233
MDA-MB-361 CTRP2 7.7172 14.7369 3.0011 9.7876
MDA-MB-453 CTRP2 7.7757 11.9483 4.3803 4.2719
MDA-MB-157 CTRP2 7.7888 9.9947 5.2639 1.0841
CAL-148 CTRP2 7.8744 18.0641 1.4832 15.1093
BT-474 CTRP2 7.8756 9.138 5.6344 0.1548
HCC1143 CTRP2 7.8762 10.4334 5.123 1.4601
MCF-7 CTRP2 7.9425 9.9799 5.3437 0.7502
HCC38 CTRP2 7.9638 9.7599 5.4396 0.497
HCC1419 CTRP2 8.0019 9.5569 5.5319 0.2877
HCC1569 CTRP2 8.0222 11.6258 4.6788 2.8614
HCC1395 CTRP2 8.1506 9.9318 5.4529 0.3876
MDA-MB-468 CTRP2 8.1676 15.0306 3.174 8.4444
CAL-85-1 CTRP2 8.234 10.398 5.3098 0.6743
JIMT-1 CTRP2 8.3987 9.614 5.6571 0.0519
CAL-51 CTRP2 8.4357 9.9867 5.5433 0.1563
HDQ-P1 CTRP2 8.728 10.4679 5.4823 0.175
HCC1806 CTRP2 8.799 10.3334 5.5536 0.0892
CAMA-1 CTRP2 9.2876 26.4501 -1.5979 21.5801
BT164 CTRP2 6.4947 9.2046 4.822 4.3316
BT 428 CTRP2 6.5368 9.6602 4.6287 5.0653
BT 239 CTRP2 6.6758 9.5063 4.8073 4.1005
BT 231 CTRP2 6.8063 11.5875 3.8793 7.7214
BT 187 CTRP2 6.9834 8.8679 5.3173 1.649
BT 145 CTRP2 7.0042 10.9106 4.3574 5.4375
BT 228 CTRP2 7.0479 8.5946 5.4766 1.0102
BT 248 CTRP2 7.0654 12.0399 3.8491 7.4216
BT 216 CTRP2 7.1133 9.4784 5.1153 2.2602
BT 172 CTRP2 7.1366 8.7794 5.444 1.0396
BT 416 CTRP2 7.1373 8.8473 5.4148 1.1385
BT 498 CTRP2 7.2511 8.3671 5.6693 0.3007
BT147 CTRP2 7.2698 8.7964 5.5057 0.7324
BT 320 CTRP2 7.3291 8.4889 5.6558 0.2957
BT 440 CTRP2 7.354 14.8054 2.7016 11.5337
BT 224 CTRP2 7.3625 9.8274 5.1057 2.0114
BT 444 CTRP2 7.4614 8.8476 5.5746 0.4228
BT 422 CTRP2 7.4779 8.6716 5.6487 0.2499
BT 330 CTRP2 7.6356 8.7367 5.6867 0.1367
BT 232 CTRP2 7.7904 9.0612 5.6295 0.1838
BT 286 CTRP2 7.8038 9.3871 5.5142 0.4006
BT 340 CTRP2 7.8073 8.9933 5.6601 0.1346
BT 271 CTRP2 7.8676 9.0883 5.649 0.1365
BT 482 CTRP2 8.0125 9.5094 5.5535 0.2458
BT 131 CTRP2 8.078 9.4972 5.583 0.1808
BT 333 CTRP2 8.0909 9.2034 5.689 0.0587
BT 359 CTRP2 8.1665 9.5528 5.5962 0.143
BT 245 CTRP2 8.1723 9.6202 5.5747 0.1705
BT 328 CTRP2 8.293 9.3672 5.7031 0.0326
BT 112 CTRP2 8.5162 14.1893 3.8014 5.5691
BT 504 CTRP2 9.5456 21.2948 1.103 13.8056
BT 139 CTRP2 13.0996 36.0776 -3.5769 20.7086
BT 159 CTRP2 13.6071 29.892 -0.321 12.9045
BT 179 CTRP2 14.4677 35.5731 -2.429 16.9119
⏷ Show the Full List of 72 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.9584 8.9191 5.7386 0.0363
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 2.23 5.371 2.0443 26.0468
SF539 CTRP2 5.8077 13.4319 2.1515 16.5008
SNU-489 CTRP2 6.2051 7.4796 5.4559 2.1805
SNU-738 CTRP2 6.2431 7.2776 5.5846 1.5815
SNU-626 CTRP2 6.3226 7.593 5.488 1.8535
SNU-466 CTRP2 6.7066 13.7932 2.7071 12.6346
SW1783 CTRP2 6.7716 10.7932 4.2454 6.2667
Daoy CTRP2 6.8948 8.61 5.3819 1.5082
KNS-81 CTRP2 7.0203 8.3142 5.5826 0.6845
SF268 CTRP2 7.0306 12.2327 3.7288 7.9691
GB-1 CTRP2 7.0723 8.8654 5.3705 1.358
42-MG-BA CTRP2 7.1695 10.0233 4.8963 3.0371
CAS-1 CTRP2 7.1878 8.6358 5.5319 0.7133
8-MG-BA CTRP2 7.2135 10.5307 4.6848 3.8127
ONS-76 CTRP2 7.3742 10.8057 4.6598 3.6977
LN-18 CTRP2 7.3769 8.287 5.7491 0.1084
KNS-60 CTRP2 7.4005 8.3725 5.7276 0.1343
KG-1-C CTRP2 7.5012 8.7438 5.6313 0.2762
KALS-1 CTRP2 7.6014 10.026 5.1525 1.6046
GaMG CTRP2 7.6069 9.3884 5.4255 0.734
Hs 683 CTRP2 7.6853 9.0673 5.5857 0.2977
SNB-75 CTRP2 7.6861 10.4514 5.0119 2.0127
SNU-1105 CTRP2 7.6964 17.3261 1.7142 14.6061
DK-MG CTRP2 7.7742 8.9115 5.6765 0.1199
YKG-1 CTRP2 7.878 9.0363 5.6709 0.1068
SF126 CTRP2 7.9098 11.7555 4.5531 3.4505
KNS-42 CTRP2 8.0392 12.5639 4.2591 4.4111
TM-31 CTRP2 8.0538 11.3178 4.8341 2.2757
CCF-STTG1 CTRP2 8.0598 13.49 3.8374 6.0148
SW1088 CTRP2 8.0611 14.6096 3.3036 8.0948
U-118MG CTRP2 8.1324 9.5859 5.5719 0.1838
NMC-G1 CTRP2 8.3003 9.3852 5.6996 0.0339
SNU-201 CTRP2 8.4461 14.6341 3.5482 6.6227
LN-229 CTRP2 8.5089 9.8001 5.6326 0.0586
SF295 CTRP2 8.5101 9.9017 5.599 0.0851
Becker CTRP2 8.5689 15.9249 3.0166 8.4813
DBTRG-05MG CTRP2 8.5901 9.9728 5.6027 0.0728
M059K CTRP2 8.9287 14.2817 4.0088 4.3236
U-251MG CTRP2 9.4246 16.3644 3.3552 6.1424
A-172 CTRP2 9.5578 18.0819 2.6411 8.5582
YH-13 CTRP2 10.5424 18.9364 2.849 6.6816
GMS-10 CTRP2 10.6102 17.9772 3.3162 5.0302
U-87MG ATCC CTRP2 11.6381 23.3098 1.5082 9.8671
T98G CTRP2 11.98 26.2848 0.3398 12.9469
GOS-3 CTRP2 11.9969 23.287 1.7335 8.7732
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-50B CTRP2 6.4561 8.4188 5.1803 2.9104
AN3-CA CTRP2 6.6182 10.0391 4.5028 5.4527
HEC-151 CTRP2 6.7307 8.0271 5.5498 1.0688
JHUEM-1 CTRP2 6.8578 10.1042 4.646 4.4813
JHUEM-2 CTRP2 7.1162 9.1231 5.28 1.6397
MFE-296 CTRP2 7.1403 10.0398 4.8696 3.1802
ESS-1 CTRP2 7.2132 9.0239 5.379 1.1905
JHUEM-7 CTRP2 7.2342 9.8922 4.9985 2.5605
MFE-319 CTRP2 7.2764 12.2013 3.9225 6.793
EN CTRP2 7.346 11.2558 4.4274 4.6558
HEC-108 CTRP2 7.3628 8.6316 5.6154 0.3735
HEC-6 CTRP2 7.4225 10.8056 4.6909 3.5142
RL95-2 CTRP2 7.4725 15.1296 2.6301 11.6126
HEC-59 CTRP2 7.4827 9.757 5.2054 1.5343
HEC-265 CTRP2 7.6806 8.743 5.7011 0.1074
HEC-251 CTRP2 7.7263 9.2494 5.5339 0.391
EFE-184 CTRP2 7.8029 9.5228 5.4615 0.5243
HEC-1-B CTRP2 7.8375 9.7591 5.3836 0.7055
HEC-1-A CTRP2 8.0665 15.2605 2.9933 9.2879
JHUEM-3 CTRP2 8.6187 16.0633 2.9838 8.5365
KLE CTRP2 8.8876 10.7294 5.4494 0.1848
Ishikawa (Heraklio) 02 ER- CTRP2 7.4122 8.4433 5.7066 0.165
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 6.6618 9.8881 4.6097 4.9383
RCC10RGB CTRP2 6.9853 10.1449 4.7154 4.0098
TUHR10TKB CTRP2 7.034 8.7023 5.4214 1.2156
TUHR4TKB CTRP2 7.0983 8.2452 5.649 0.4337
VMRC-RCZ CTRP2 7.1545 9.738 5.0204 2.5738
786-O CTRP2 7.1891 10.0411 4.9005 2.9955
KMRC-1 CTRP2 7.5395 9.5739 5.3148 1.1192
A-498 CTRP2 7.5662 9.0319 5.5488 0.4322
VMRC-RCW CTRP2 7.7174 10.0079 5.222 1.2715
ACHN CTRP2 7.7995 12.8506 3.9694 5.8488
Caki-2 CTRP2 7.952 16.3918 2.3615 11.8534
KMRC-2 CTRP2 7.9558 12.3798 4.2926 4.3855
OS-RC-2 CTRP2 8.0667 10.4529 5.2104 1.0446
BFTC-909 CTRP2 8.1874 9.496 5.6235 0.1072
CAL-54 CTRP2 8.2389 10.2738 5.3601 0.5517
769-P CTRP2 8.248 9.6973 5.5756 0.1529
TUHR14TKB CTRP2 8.3024 16.6093 2.5049 10.7834
Caki-1 CTRP2 8.3694 10.5906 5.2942 0.6436
SNU-1272 CTRP2 8.473 9.7866 5.6249 0.068
KMRC-20 CTRP2 8.687 10.1908 5.5628 0.095
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
T84 CTRP2 5.5175 7.9418 4.6274 7.0579
SW1116 CTRP2 5.7903 10.6843 3.5094 11.1367
SW620 CTRP2 5.9714 7.4015 5.3041 3.2555
COLO 320 CTRP2 6.0436 8.1798 4.976 4.4923
HCT 15 CTRP2 6.0714 7.332 5.423 2.5603
LoVo CTRP2 6.1463 8.4427 4.9291 4.495
SNU-407 CTRP2 6.3824 7.9069 5.3776 2.2141
LS123 CTRP2 6.5142 8.7421 5.0642 3.2972
SNU-C5 CTRP2 6.5817 9.0149 4.9797 3.539
SNU-61 CTRP2 6.6416 11.9543 3.5712 9.2732
GP2d CTRP2 6.8311 17.6876 0.8647 18.9817
SNU-C1 CTRP2 6.9547 8.5134 5.4606 1.1561
RKO CTRP2 7.0259 8.9401 5.3097 1.6294
HCT 8 CTRP2 7.0629 10.3976 4.647 4.1743
HT115 CTRP2 7.1152 8.969 5.3486 1.3924
C2BBe1 CTRP2 7.2197 9.4489 5.1932 1.8458
SNU-175 CTRP2 7.2916 24.3749 -2.1034 25.8808
HT-55 CTRP2 7.2936 8.7487 5.537 0.6228
HT-29 CTRP2 7.3914 8.4961 5.679 0.2223
CW-2 CTRP2 7.4053 11.1794 4.5033 4.2731
MDST8 CTRP2 7.4608 10.638 4.7933 3.071
LS1034 CTRP2 7.4964 8.9404 5.5537 0.456
KM12 CTRP2 7.5169 9.1587 5.4762 0.6494
DLD-1 CTRP2 7.5488 8.3732 5.7809 0.0449
HCT 116 CTRP2 7.6159 8.8678 5.6317 0.2334
NCI-H716 CTRP2 7.6636 13.8845 3.3781 8.3884
SNU-C4 CTRP2 7.6838 8.9402 5.632 0.2107
RCM-1 [Human ESC] CTRP2 7.7563 9.0307 5.6274 0.1969
LS411N CTRP2 7.7706 8.852 5.6959 0.0969
COLO205 CTRP2 7.7874 8.9636 5.6631 0.1349
HCC-56 CTRP2 7.8176 8.9071 5.6938 0.0912
LS513 CTRP2 7.8382 9.2352 5.585 0.2449
CCK-81 CTRP2 7.9136 13.7631 3.6098 7.1073
OUMS-23 CTRP2 7.9484 8.9121 5.7376 0.0378
NCI-H508 CTRP2 7.9812 9.4857 5.5498 0.262
SK-CO-1 CTRP2 8.0573 9.487 5.5788 0.1922
COLO201 CTRP2 8.112 9.1514 5.7135 0.0396
LS180 CTRP2 8.1739 9.5224 5.6095 0.1253
SNU-C2A CTRP2 8.206 10.2061 5.372 0.5396
SW948 CTRP2 8.2367 9.473 5.6487 0.0754
SW48 CTRP2 8.3117 9.8809 5.5346 0.1949
CL-11 CTRP2 8.5734 10.3659 5.4608 0.2394
COLO 678 CTRP2 9.0149 18.8662 1.9084 11.8826
SNU-503 CTRP2 9.9532 20.5459 1.7352 11.1836
NCI-H747 CTRP2 10.0488 31.6011 -3.5696 24.5222
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 CTRP2 0.456 1.504 -2.2756 0.0443
SNU-886 CTRP2 6.1573 7.9563 3.4879 0.4818
SNU-878 CTRP2 6.4368 8.4465 5.1526 3.0556
JHH-4 CTRP2 6.5514 8.8748 5.0262 3.3949
SNU-423 CTRP2 6.5995 8.3391 5.3202 2.1246
Li-7 CTRP2 6.6957 8.5264 5.2952 2.0917
HuH-6 CTRP2 6.7133 9.0569 5.0526 3.0412
SK-HEP-1 CTRP2 6.7155 8.6915 5.2297 2.3252
SNU-398 CTRP2 6.9087 13.5142 3.003 11.1082
SNU-761 CTRP2 6.9527 9.2842 5.1045 2.5028
PLC/PRF/5 CTRP2 7.0197 10.8483 4.3987 5.2453
JHH-5 CTRP2 7.0381 11.1941 4.2433 5.8518
SNU-449 CTRP2 7.1257 13.243 3.3017 9.5449
Hep-G2 CTRP2 7.1511 8.2414 4.6969 0.0504
JHH-2 CTRP2 7.1511 11.8875 3.9859 6.7279
JHH-6 CTRP2 7.4277 8.5886 5.6592 0.2478
SNU-475 CTRP2 7.6972 9.5015 5.4221 0.686
HuH-1 CTRP2 7.7386 9.3158 5.5137 0.4313
Hep 3B2.1-7 CTRP2 7.9199 9.3802 5.5643 0.2558
SNU-182 CTRP2 8.6382 10.3632 5.4859 0.1887
SNU-387 CTRP2 10.1823 20.3855 1.9593 10.1373
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 143 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H446 CTRP2 2.9972 6.1847 2.6796 21.4141
NCI-H2171 CTRP2 4.5673 9.8467 2.8058 16.703
NCI-H1155 CTRP2 5.1971 8.73 3.9435 10.6132
NCI-H1693 CTRP2 5.4309 13.5918 1.748 18.7715
NCI-H1341 CTRP2 5.6883 14.2494 1.6415 18.6091
NCI-H1105 CTRP2 6.1704 10.0172 4.162 7.6704
NCI-H2081 CTRP2 6.1788 9.1031 4.6256 5.7092
COR-L279 CTRP2 6.1836 11.5341 3.4147 10.7556
DV-90 CTRP2 6.1872 12.21 3.0797 12.1163
DMS 53 CTRP2 6.189 9.1823 4.5942 5.8221
LK2 CTRP2 6.2214 7.4589 5.4786 2.0576
NCI-H520 CTRP2 6.2824 7.7232 5.3941 2.3069
NCI-H1581 CTRP2 6.3115 8.3577 5.1021 3.4744
RERF-LC-MS CTRP2 6.3386 7.706 5.4442 2.0088
DMS 454 CTRP2 6.3505 11.9751 3.3301 10.7889
NCI-H810 CTRP2 6.3528 9.5218 4.5555 5.6875
SHP-77 CTRP2 6.4061 7.9072 5.3946 2.1074
NCI-H2106 CTRP2 6.4382 9.5414 4.6123 5.3008
NCI-H1092 CTRP2 6.5988 8.63 5.1794 2.6949
NCI-H841 CTRP2 6.621 8.2323 5.3856 1.8338
NCI-H1755 CTRP2 6.6266 12.3284 3.3734 10.11
NCI-H1703 CTRP2 6.6328 15.7479 1.6739 16.6302
NCI-H1694 CTRP2 6.6334 10.2028 4.4333 5.7161
NCI-H1944 CTRP2 6.6485 8.5206 5.2664 2.2718
NCI-H526 CTRP2 6.6786 8.0388 5.5131 1.2649
EKVX CTRP2 6.6831 9.1927 4.9655 3.4405
NCI-H2029 CTRP2 6.6872 11.4962 3.8339 8.1108
DMS 273 CTRP2 6.7052 10.7076 4.238 6.4069
NCI-H2110 CTRP2 6.7286 9.6479 4.7761 4.1466
NCI-H226 CTRP2 6.7599 8.2984 5.4432 1.434
NCI-H1339 CTRP2 6.8342 8.6127 5.3436 1.7247
NCI-H1568 CTRP2 6.8581 8.9618 5.1953 2.2702
NCI-H661 CTRP2 6.8875 9.2417 5.082 2.6781
Sq-1 CTRP2 6.9042 9.0025 5.2058 2.1699
NCI-H2023 CTRP2 6.9142 10.0282 4.7226 4.0847
Lu-99 CTRP2 6.9267 10.197 4.6495 4.3633
HOP-62 CTRP2 6.9602 9.2589 5.1213 2.4277
NCI-H1395 CTRP2 6.9763 11.8603 3.8719 7.4718
RERF-LC-A1 CTRP2 6.9875 8.6732 5.4079 1.3115
NCI-H69 CTRP2 7.0163 10.3184 4.6531 4.217
Calu-6 CTRP2 7.0324 8.6119 5.4605 1.0802
COLO 668 CTRP2 7.0413 11.583 4.0556 6.615
HOP-92 CTRP2 7.0578 9.9651 4.8507 3.3654
NCI-H211 CTRP2 7.0863 9.6828 5.0029 2.7277
NCI-H1869 CTRP2 7.0919 10.9113 4.419 5.0545
VMRC-LCD CTRP2 7.1173 10.0974 4.8271 3.3785
BEN CTRP2 7.1396 7.9396 5.7831 0.117
DMS 114 CTRP2 7.1438 8.7651 5.4542 0.9991
NCI-H358 CTRP2 7.1644 9.5337 5.1213 2.1768
HCC2935 CTRP2 7.1816 10.9587 4.4582 4.7647
SW1573 CTRP2 7.1858 10.5811 4.6423 4.0202
NCI-H838 CTRP2 7.1978 10.4859 4.6957 3.7909
NCI-H2196 CTRP2 7.2075 8.8805 5.4382 0.9964
HCC1438 CTRP2 7.2474 8.8576 5.4687 0.8642
NCI-H2228 CTRP2 7.2553 20.1335 -0.0182 20.8612
RERF-LC-Ad1 CTRP2 7.2659 8.1331 5.762 0.1164
LOU-NH91 CTRP2 7.3185 11.1108 4.4782 4.4913
HCC1833 CTRP2 7.33 9.3722 5.2904 1.3855
A-549 CTRP2 7.3367 9.2931 5.3286 1.2484
NCI-H1838 CTRP2 7.3519 9.9951 5.0231 2.3291
NCI-H2126 CTRP2 7.3778 8.5754 5.6435 0.3016
NCI-H1915 CTRP2 7.3784 9.1841 5.3975 0.9856
EBC-1 CTRP2 7.3812 10.3179 4.8923 2.7891
NCI-H727 CTRP2 7.3837 9.5131 5.258 1.4463
NCI-H2087 CTRP2 7.3975 9.7527 5.1596 1.7795
NCI-H1793 CTRP2 7.3996 11.7589 4.2224 5.4005
COR-L88 CTRP2 7.3999 16.0432 2.1248 13.6315
NCI-H1650 CTRP2 7.4034 10.7806 4.6904 3.5405
HCC44 CTRP2 7.4319 9.6248 5.2355 1.4785
MOR/CPR CTRP2 7.4363 8.481 5.7022 0.1652
HCC15 CTRP2 7.4677 11.053 4.6036 3.7963
SBC-5 CTRP2 7.4828 8.4676 5.7248 0.1182
HCC827 CTRP2 7.5064 10.3524 4.9524 2.4182
NCI-H1435 CTRP2 7.5083 10.4771 4.8967 2.6237
T3M-10 CTRP2 7.5202 12.7302 3.8372 6.7716
LUDLU-1 CTRP2 7.5316 12.3287 4.0387 5.9481
NCI-H650 CTRP2 7.546 9.6248 5.2965 1.1728
PC-14 CTRP2 7.5732 9.7781 5.245 1.3183
NCI-H322 CTRP2 7.6084 9.7432 5.2784 1.1798
COR-L47 CTRP2 7.6643 17.0724 1.8153 14.3032
NCI-H1184 CTRP2 7.7119 9.9028 5.2637 1.1433
NCI-H1666 CTRP2 7.734 9.655 5.3773 0.7876
DMS 79 CTRP2 7.7418 15.5399 2.6262 11.1921
Calu-3 CTRP2 7.7475 10.7552 4.9113 2.3092
NCI-H460 CTRP2 7.7715 8.8412 5.7 0.0921
NCI-H522 CTRP2 7.7734 15.5909 2.6241 11.1499
HCC2108 CTRP2 7.7748 9.8118 5.3328 0.8881
SK-MES-1 CTRP2 7.789 12.0882 4.3232 4.4765
NCI-H2444 CTRP2 7.795 9.125 5.6083 0.2177
NCI-H2141 CTRP2 7.8395 21.968 -0.4753 21.1005
HCC4006 CTRP2 7.8498 9.3593 5.5438 0.3192
IA-LM CTRP2 7.858 9.3333 5.5568 0.2907
HCC2279 CTRP2 7.894 9.9615 5.3285 0.8218
HCC95 CTRP2 7.9052 9.7859 5.4037 0.6142
HARA [Human squamous cell lung carcinoma] CTRP2 7.9266 12.5221 4.2076 4.7495
Calu-1 CTRP2 7.9636 12.1246 4.4159 3.9051
NCI-H889 CTRP2 7.9647 9.836 5.4105 0.5661
NCI-H1373 CTRP2 7.9953 11.0764 4.9081 2.0752
SK-LU-1 CTRP2 8.0376 9.832 5.4435 0.4545
COR-L95 CTRP2 8.0393 9.4469 5.5863 0.1855
LCLC-103H CTRP2 8.0477 9.1339 5.6975 0.0567
HCC1195 CTRP2 8.0558 9.5605 5.5518 0.2357
HCC78 CTRP2 8.057 9.7589 5.4792 0.3703
NCI-H1734 CTRP2 8.071 9.9334 5.4189 0.4946
NCI-H1573 CTRP2 8.073 10.3302 5.2634 0.8896
NCI-H196 CTRP2 8.1001 14.2794 3.4884 7.3203
LXF 289 CTRP2 8.1111 13.4239 3.9021 5.6961
NCI-H1651 CTRP2 8.1179 14.3417 3.4707 7.3646
HCC1588 CTRP2 8.131 9.5289 5.5915 0.1567
NCI-H2286 CTRP2 8.1332 9.3492 5.6545 0.0837
SW1271 CTRP2 8.1333 14.5576 3.3777 7.7045
HCC1171 CTRP2 8.1545 10.2543 5.3309 0.6639
NCI-H2291 CTRP2 8.1774 10.3752 5.2935 0.7465
KNS-62 CTRP2 8.1983 14.9151 3.2503 8.1064
COLO 699 CTRP2 8.2086 11.8876 4.6684 2.706
NCI-H1623 CTRP2 8.2889 14.3479 3.5811 6.7034
LC-1/sq-SF CTRP2 8.2919 13.8941 3.7972 5.867
NCI-H2342 CTRP2 8.3354 14.6612 3.4631 7.096
NCI-H2172 CTRP2 8.3638 9.902 5.5465 0.1668
NCI-H1975 CTRP2 8.4016 10.0868 5.4953 0.231
CAL-12T CTRP2 8.4093 10.0188 5.5223 0.1896
NCI-H2030 CTRP2 8.422 9.8206 5.5956 0.1
NCI-H647 CTRP2 8.4293 10.412 5.3874 0.4132
LCLC-97TM1 CTRP2 8.4324 10.2097 5.4629 0.2743
NCI-H2122 CTRP2 8.4531 9.8697 5.5899 0.1012
NCI-H2009 CTRP2 8.5416 10.2656 5.4844 0.2124
NCI-H2170 CTRP2 8.581 15.818 3.0756 8.242
HCC366 CTRP2 8.5869 10.175 5.5327 0.1408
NCI-H1563 CTRP2 8.692 16.3015 2.9191 8.6789
NCI-H2405 CTRP2 8.7187 10.5935 5.4346 0.2422
NCI-H1355 CTRP2 8.7365 10.5664 5.4509 0.2147
NCI-H2085 CTRP2 8.7769 10.8422 5.3675 0.3331
Lu-65 CTRP2 8.7911 21.8177 0.3133 17.3502
NCI-H292 CTRP2 8.8493 15.0702 3.5997 5.9214
NCI-H441 CTRP2 8.8594 10.2144 5.6138 0.0426
ChaGo-K-1 CTRP2 8.9106 16.4971 2.9702 8.1942
NCI-H1792 CTRP2 9.0436 10.8572 5.4614 0.1434
NCI-H1299 CTRP2 9.0741 10.68 5.532 0.0765
COR-L51 CTRP2 9.4579 23.2937 0.0725 17.0389
NCI-H23 CTRP2 9.9776 20.7387 1.6598 11.4023
RERF-LC-Ad2 CTRP2 12.7931 22.75 2.4191 5.8931
COR-L105 CTRP2 13.2271 29.7464 -0.4894 13.751
Hs 888.Lu CTRP2 7.7931 12.5818 4.093 5.3711
⏷ Show the Full List of 143 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 6.5107 12.4917 3.2006 11.0219
P-STS CTRP2 8.0667 9.7766 5.4766 0.3719
SYO-1 CTRP2 8.3545 9.5713 5.6563 0.0565
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.5857 15.1923 1.9133 15.8597
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 7.8393 13.7258 3.5771 7.342
Aska-SS CTRP2 7.8434 9.2139 5.5949 0.226
GCT CTRP2 6.0137 8.1806 4.9506 4.6571
Rh41 CTRP2 6.2157 9.048 4.6828 5.4008
HT-1080 CTRP2 6.3734 7.9019 5.3735 2.245
A-204 CTRP2 6.6631 14.8507 2.1456 14.8607
MES-SA CTRP2 6.6746 8.0144 5.5219 1.2363
TE 441.T CTRP2 6.7622 8.211 5.4847 1.2748
KYM-1 CTRP2 6.7893 9.0825 5.0923 2.772
RKN CTRP2 6.8912 8.4172 5.4673 1.1977
SK-LMS-1 CTRP2 7.1326 11.2161 4.2998 5.4781
BT-12 CTRP2 7.1807 14.1227 2.9087 11.0165
G-401 CTRP2 7.623 15.6829 2.4691 11.978
TTC-709 CTRP2 7.7189 9.0996 5.5873 0.2817
TE 617.T CTRP2 7.7259 9.3333 5.5015 0.4663
BT-16 CTRP2 7.7358 8.9684 5.642 0.1789
Tm87-16 CTRP2 7.9965 9.3512 5.6041 0.1697
SW982 CTRP2 8.377 9.7602 5.6004 0.1018
Rh18 CTRP2 8.4098 9.8572 5.5788 0.1194
Hs 729.T CTRP2 9.1223 13.5412 4.4437 2.6235
G-402 CTRP2 11.4637 24.1843 0.9949 11.6456
SK-UT-1 CTRP2 12.9943 27.1762 0.5552 11.1989
RD CTRP2 14.2525 27.4844 1.1451 8.3011
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 8.6129 10.4654 5.4402 0.2608
SNU-119 CTRP2 5.6601 10.836 3.3213 12.1788
OV7 CTRP2 5.9212 7.8406 5.0416 4.459
ES2 CTRP2 6.3614 7.5394 5.5418 1.5736
A2780 CTRP2 6.3656 7.9608 5.3389 2.4
OV-90 CTRP2 6.4241 9.7443 4.5006 5.7918
SNU-8 CTRP2 6.62 7.7378 5.6157 0.9475
MCAS CTRP2 6.698 8.6139 5.2551 2.248
OC 314 CTRP2 6.8167 8.9505 5.1736 2.4105
TYK-nu CTRP2 6.9305 9.3408 5.0633 2.6945
OAW28 CTRP2 7.0988 10.9262 4.4166 5.0542
RMG-I CTRP2 7.1072 11.2927 4.2446 5.7408
HEY A8 CTRP2 7.1128 9.5193 5.0961 2.3342
EFO-27 CTRP2 7.189 9.2128 5.2818 1.5561
ONCO-DG-1 CTRP2 7.229 9.1489 5.3328 1.3352
DOV13 CTRP2 7.3628 11.453 4.3443 4.9645
COV434 CTRP2 7.378 9.8321 5.1127 1.9693
OAW42 CTRP2 7.3838 8.6706 5.6095 0.3774
JHOM-1 CTRP2 7.3903 11.8409 4.1767 5.5975
Caov-3 CTRP2 7.5254 9.1996 5.4636 0.6793
OVCAR-5 CTRP2 7.572 11.2371 4.5839 3.7404
OVK18 CTRP2 7.6213 9.2993 5.4681 0.6075
OV56 CTRP2 7.6495 8.6825 5.7108 0.1014
EFO-21 CTRP2 7.7679 9.6601 5.3912 0.7272
TOV-112D CTRP2 7.7821 9.6091 5.4181 0.6462
JHOC-5 CTRP2 7.8683 9.3243 5.5643 0.2729
SK-OV-3 CTRP2 7.88 11.327 4.7307 2.8248
COV362 CTRP2 7.8919 13.0844 3.9194 5.9198
JHOS-2 CTRP2 7.9481 11.6855 4.6082 3.2015
OVTOKO CTRP2 7.9634 10.2628 5.2386 1.0337
IGROV-1 CTRP2 8.043 9.963 5.3954 0.563
FU-OV-1 CTRP2 8.1163 10.2263 5.3248 0.7
SNU-840 CTRP2 8.1374 11.9898 4.5817 3.0914
OVCAR-8 CTRP2 8.2425 9.702 5.572 0.1588
OVISE CTRP2 8.2453 9.2852 5.7141 0.03
Kuramochi CTRP2 8.3111 10.1847 5.424 0.3848
OVSAHO CTRP2 8.4636 9.6328 5.6727 0.0374
OVCAR-4 CTRP2 8.5672 10.3013 5.4814 0.2108
COV644 CTRP2 12.2802 25.4948 0.8941 11.0055
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP2 6.3289 7.785 5.3983 2.2134
NCI-H2452 CTRP2 6.7486 10.4896 4.3779 5.7563
NCI-H2052 CTRP2 7.0124 9.534 5.0254 2.7356
ACC-MESO-1 CTRP2 7.1762 9.4224 5.1794 1.9449
MPP 89 CTRP2 7.5219 10.4926 4.8977 2.6042
IST-Mes1 CTRP2 8.6256 10.2318 5.5271 0.1405
JL-1 CTRP2 12.7794 23.2887 2.1772 6.6364
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 6.2868 9.586 4.4714 6.1584
PaCa-3 CTRP2 6.4789 7.7645 5.514 1.5172
DU145 CTRP2 7.0212 10.0238 4.7981 3.6259
NCI-H660 CTRP2 7.3195 14.336 2.9074 10.7906
VCaP CTRP2 8.1678 9.5196 5.6083 0.1279
22Rv1 CTRP2 8.6315 10.6505 5.3804 0.356
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 6.5382 9.0539 4.9287 3.8185
YD-15 CTRP2 9.4417 16.5765 3.2682 6.4377
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 CTRP2 3.8447 5.9755 3.6622 15.2912
HGC-27 CTRP2 5.01 17.2153 -0.4249 26.3824
SNU-16 CTRP2 5.1887 7.2047 4.656 7.7293
SNU-5 CTRP2 5.39 9.882 3.5563 11.7818
GSS CTRP2 6.1082 7.2087 5.5145 2.1071
SNU-1 CTRP2 6.1547 10.2547 4.0304 8.2512
NUGC-3 CTRP2 6.8161 8.4798 4.4839 0.4971
SNU-216 CTRP2 6.8828 8.9322 5.2251 2.1219
SNU-601 CTRP2 6.9327 10.6231 4.4465 5.1831
GSU CTRP2 7.0308 7.4898 5.8987 0.0123
SH-10-TC CTRP2 7.1029 16.137 1.8508 15.1424
SNU-620 CTRP2 7.1422 8.4122 5.602 0.5371
LMSU CTRP2 7.3049 12.0957 3.994 6.4604
Hs 746.T CTRP2 7.3414 8.7184 5.5717 0.4963
MKN45 CTRP2 7.5187 8.4919 5.7295 0.1039
ECC12 CTRP2 7.5357 8.6309 5.6865 0.1627
MKN74 CTRP2 7.704 9.5575 5.4027 0.7355
23132/87 CTRP2 7.8044 9.1654 5.5972 0.234
MKN1 CTRP2 7.8081 9.0596 5.6368 0.1678
SNU-668 CTRP2 7.8331 9.0781 5.6397 0.1573
KATO III CTRP2 7.9656 9.7053 5.4614 0.4465
NCI-N87 CTRP2 8.1578 9.9252 5.4583 0.3739
Fu97 CTRP2 8.2182 9.8186 5.5214 0.2393
AGS CTRP2 8.3408 10.0493 5.4854 0.2634
IM95 CTRP2 8.4403 10.7442 5.2656 0.677
NUGC-4 CTRP2 8.5972 10.1374 5.5494 0.1208
MKN7 CTRP2 8.7347 17.6366 2.3082 10.8689
SNU-719 CTRP2 8.9741 10.6626 5.5033 0.1119
KE-39 CTRP2 8.9909 13.969 4.1847 3.6308
HuG1-N CTRP2 11.4464 26.3993 -0.0597 14.7084
SNU-1077 CTRP2 6.9018 8.6438 5.3707 1.5422
SNU-685 CTRP2 7.2469 8.9795 5.4164 1.0344
SNG-M CTRP2 7.303 9.1534 5.3711 1.1357
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
B-CPAP CTRP2 5.3381 7.7581 4.5457 7.8099
FTC-238 CTRP2 6.1328 7.598 5.3399 2.7949
FTC-133 CTRP2 6.6229 9.7525 4.6476 4.8444
ML-1 [Human leukemia] CTRP2 6.9095 11.1296 4.1818 6.306
TT CTRP2 6.9833 9.4191 5.0607 2.635
SW579 CTRP2 7.0691 8.6401 5.4682 1.0191
CGTH-W-1 CTRP2 7.1696 12.5369 3.6814 7.9381
8505C CTRP2 7.3662 11.0747 4.5271 4.2314
TT2609-C02 CTRP2 7.608 11.49 4.4883 4.066
BHT-101 CTRP2 7.7213 9.0162 5.619 0.2218
CAL-62 CTRP2 7.9963 9.1722 5.6665 0.0917
8305C CTRP2 8.1667 9.8045 5.5064 0.2801
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 4.6546 35.7776 -9.9957 39.6028
HSC-2 CTRP2 6.2333 7.5793 5.4281 2.248
FaDu CTRP2 6.3886 7.4728 5.5927 1.3282
PE/CA-PJ34 (clone C12) CTRP2 6.6478 11.1779 3.9615 7.6504
PE/CA-PJ15 CTRP2 7.0332 9.1067 5.2378 1.8899
BICR 6 CTRP2 7.0814 8.6873 5.4543 1.0551
PE/CA-PJ41 (clone D2) CTRP2 7.1058 8.7881 5.4235 1.1382
BICR 16 CTRP2 7.1639 11.6763 4.0981 6.251
SCC-25 CTRP2 7.2677 10.3749 4.794 3.3102
HSC-3 CTRP2 7.3072 9.5305 5.2073 1.7013
BICR 56 CTRP2 7.3159 10.5554 4.7401 3.4588
SNU-1076 CTRP2 7.3963 11.4402 4.373 4.803
BICR 22 CTRP2 7.6134 10.4603 4.9664 2.2509
SNU-1214 CTRP2 7.6677 14.618 3.0236 9.7767
PE/CA-PJ49 CTRP2 7.8679 9.0741 5.6541 0.1296
BICR 31 CTRP2 7.9448 10.3422 5.1965 1.1736
SNU-1066 CTRP2 7.9613 11.8765 4.5287 3.4826
HSC-4 CTRP2 8.0588 13.1365 4.0038 5.3698
SNU-46 CTRP2 8.151 10.5445 5.2133 0.98
CAL-33 CTRP2 8.2725 16.1412 2.7107 10.0587
SCC-4 CTRP2 8.3652 9.7812 5.589 0.1156
SNU-899 CTRP2 8.447 9.7494 5.6284 0.068
BICR 18 CTRP2 8.4721 10.6233 5.3256 0.5247
BHY CTRP2 8.4765 9.8912 5.5908 0.097
Detroit 562 CTRP2 8.5331 10.19 5.5079 0.1819
CAL-27 CTRP2 8.7594 20.457 0.9564 15.4333
YD-8 CTRP2 8.7923 15.0207 3.5873 6.0371
SNU-1041 CTRP2 8.9943 14.3489 4.0167 4.225
SCC-9 CTRP2 10.169 18.803 2.6869 7.6572
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 CTRP2 6.2514 7.4567 5.5024 1.9085
253J CTRP2 6.344 8.1126 5.2481 2.8112
BC-3C CTRP2 6.5738 8.1435 5.3965 1.8549
SCaBER CTRP2 6.6983 8.5981 5.2628 2.2167
5637 CTRP2 6.7839 9.3181 4.9754 3.2509
JMSU-1 CTRP2 6.7886 8.8122 5.2207 2.2616
HT-1197 CTRP2 6.819 10.4138 4.4669 11.1328
TCCSUP CTRP2 6.8451 8.6442 5.3357 1.7416
T24 CTRP2 6.8893 8.6496 5.3604 1.5952
KMBC-2 CTRP2 6.9279 9.5326 4.9703 3.0673
VM-CUB-1 CTRP2 6.9907 9.129 5.2013 2.0795
KU-19-19 CTRP2 7.0351 8.4843 5.5176 0.8834
639V CTRP2 7.0752 8.1275 5.6853 0.3509
HT-1376 CTRP2 7.2483 9.4225 5.2218 1.7105
U-BLC1 CTRP2 7.2741 9.3705 5.2599 1.5472
RT-112 CTRP2 7.4386 9.5426 5.2751 1.337
BFTC-905 CTRP2 7.5854 8.8764 5.6162 0.2743
UM-UC-1 CTRP2 7.6146 12.9236 3.8092 6.7456
RT-4 CTRP2 7.6536 9.3847 5.4488 0.6402
647V CTRP2 7.6684 10.232 5.0989 1.7259
253J-BV CTRP2 7.7623 9.1664 5.5801 0.28
CAL-29 CTRP2 7.8428 9.2592 5.5781 0.256
SW1710 CTRP2 8.41 10.0327 5.5177 0.1959
J82 CTRP2 13.2298 25.1868 1.5904 7.9719
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.5411 8.3553 5.7843 0.0431

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2653).
2 Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6322-7.