Details of the Drug

General Information of Drug (ID: DM8E4HB)

Drug Name

INC-106

Synonyms

Angiotensin II mAb (restenosis), Inncardio/Queen Mary and Westfield College; Angiotensin II type I receptor monoclonal antibody (restenosis), Inncardio/Queen Mary Univeristy

Indication

Disease Entry	ICD 11	Status	REF
Artery stenosis	BD52	Investigative	[1]
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Drug Type

Antibody

Cross-matching ID

TTD ID: D0I6HJ

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Angiotensin II receptor type-1 (AGTR1)	TT8DBY3	AGTR1_HUMAN	Not Available	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Artery stenosis

ICD Disease Classification

BD52

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Angiotensin II receptor type-1 (AGTR1)	DTT	AGTR1	8.95E-01	1.34E-02	0.07

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 34).