Details of the Drug

General Information of Drug (ID: DM8LYSB)

Drug Name
Triazine
Synonyms
Anilazine; DYRENE; Zinochlor; Anilazin; Kemate; 101-05-3; Bortrysan; Triazin; Triasyn; Triasym; Direz; Dyrene 50W; Aniyaline; Dyrene Flussig; Triazine (pesticide); 4,6-Dichloro-N-(2-chlorophenyl)-1,3,5-triazin-2-amine; 2,4-Dichloro-6-(o-chloroanilino)-s-triazine; NCI-C08684; (o-Chloroanilino)dichlorotriazine; Triazine (VAN); NSC 3851; Caswell No. 302; 2,4-Dichloro-6-(2-chloroanilino)-1,3,5-triazine; Dairene; Anilazine [BSI:ISO]; ENT 26,058; 1,3,5-Triazin-2-amine, 4,6-dichloro-N-(2-chlorophenyl)-; UNII-C6E8Y03ZJN; B-622; CCRIS 43
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 81.08
Logarithm of the Partition Coefficient (xlogp) -0.7
Rotatable Bond Count (rotbonds) 0
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C3H3N3
IUPAC Name
triazine
Canonical SMILES
C1=CN=NN=C1
InChI
InChI=1S/C3H3N3/c1-2-4-6-5-3-1/h1-3H
InChIKey
JYEUMXHLPRZUAT-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
123047
ChEBI ID
CHEMBL38058
CAS Number
12654-97-6
TTD ID
D02TJY

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) TT3PQ2Y PYRD_PLAF7 Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid. Chem Biol Interact. 2000 Jan 3;124(1):61-76.