Details of the Drug

General Information of Drug (ID: DM8MYKL)

Drug Name
SR-1001
Synonyms TH17 cell inhibitor (multiple sclerosis), Scripps
Indication
Disease Entry ICD 11 Status REF
Diabetic retinopathy 9B71.0 Preclinical [1]
Multiple sclerosis 8A40 Investigative [2]
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C15H13F6N3O4S2
Canonical SMILES
CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
InChI
InChI=1S/C15H13F6N3O4S2/c1-7-11(29-12(22-7)23-8(2)25)30(27,28)24-10-5-3-9(4-6-10)13(26,14(16,17)18)15(19,20)21/h3-6,24,26H,1-2H3,(H,22,23,25)
InChIKey
OZBSSKGBKHOLGA-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
44241473
ChEBI ID
CHEMBL3094388
TTD ID
D0O1WJ
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References

1 RORt Inhibitor-SR1001 Halts Retinal Inflammation, Capillary Degeneration, and the Progression of Diabetic Retinopathy. Int J Mol Sci. 2020 May 17;21(10):3547.
2 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.